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Fusion gene ID: 12447 |
FusionGeneSummary for FAIM_SLAIN1 |
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Fusion gene information | Fusion gene name: FAIM_SLAIN1 | Fusion gene ID: 12447 | Hgene | Tgene | Gene symbol | FAIM | SLAIN1 | Gene ID | 55179 | 122060 |
Gene name | Fas apoptotic inhibitory molecule | SLAIN motif family member 1 | |
Synonyms | FAIM1 | C13orf32 | |
Cytomap | 3q22.3 | 13q22.3 | |
Type of gene | protein-coding | protein-coding | |
Description | fas apoptotic inhibitory molecule 1 | SLAIN motif-containing protein 1 | |
Modification date | 20180519 | 20180519 | |
UniProtAcc | Q9NVQ4 | Q8ND83 | |
Ensembl transtripts involved in fusion gene | ENST00000338446, ENST00000360570, ENST00000393035, ENST00000393034, ENST00000464668, | ENST00000466548, ENST00000418532, ENST00000488699, ENST00000267219, ENST00000351546, ENST00000465831, ENST00000314070, ENST00000358679, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 4 X 4 X 2=32 |
# samples | 1 | 4 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: FAIM [Title/Abstract] AND SLAIN1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | W07321 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
3UTR-3CDS | ENST00000338446 | ENST00000466548 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000338446 | ENST00000418532 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000338446 | ENST00000488699 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000338446 | ENST00000267219 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000338446 | ENST00000351546 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3UTR | ENST00000338446 | ENST00000465831 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-intron | ENST00000338446 | ENST00000314070 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-intron | ENST00000338446 | ENST00000358679 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000360570 | ENST00000466548 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000360570 | ENST00000418532 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000360570 | ENST00000488699 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000360570 | ENST00000267219 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000360570 | ENST00000351546 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3UTR | ENST00000360570 | ENST00000465831 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-intron | ENST00000360570 | ENST00000314070 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-intron | ENST00000360570 | ENST00000358679 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000393035 | ENST00000466548 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000393035 | ENST00000418532 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000393035 | ENST00000488699 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000393035 | ENST00000267219 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000393035 | ENST00000351546 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3UTR | ENST00000393035 | ENST00000465831 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-intron | ENST00000393035 | ENST00000314070 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-intron | ENST00000393035 | ENST00000358679 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000393034 | ENST00000466548 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000393034 | ENST00000418532 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000393034 | ENST00000488699 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000393034 | ENST00000267219 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3CDS | ENST00000393034 | ENST00000351546 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-3UTR | ENST00000393034 | ENST00000465831 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-intron | ENST00000393034 | ENST00000314070 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
3UTR-intron | ENST00000393034 | ENST00000358679 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
intron-3CDS | ENST00000464668 | ENST00000466548 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
intron-3CDS | ENST00000464668 | ENST00000418532 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
intron-3CDS | ENST00000464668 | ENST00000488699 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
intron-3CDS | ENST00000464668 | ENST00000267219 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
intron-3CDS | ENST00000464668 | ENST00000351546 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
intron-3UTR | ENST00000464668 | ENST00000465831 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
intron-intron | ENST00000464668 | ENST00000314070 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
intron-intron | ENST00000464668 | ENST00000358679 | FAIM | chr3 | 138352063 | - | SLAIN1 | chr13 | 78320728 | - |
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FusionProtFeatures for FAIM_SLAIN1 |
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Hgene | Tgene |
FAIM | SLAIN1 |
Plays a role as an inducible effector molecule thatmediates Fas resistance produced by surface Ig engagement in Bcells. {ECO:0000250}. | Microtubule plus-end tracking protein that might beinvolved in the regulation of cytoplasmic microtubule dynamics,microtubule organization and microtubule elongation.{ECO:0000269|PubMed:21646404}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for FAIM_SLAIN1 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for FAIM_SLAIN1 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FAIM_SLAIN1 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FAIM_SLAIN1 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |