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Fusion gene ID: 12429 |
FusionGeneSummary for FAF1_HOOK1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FAF1_HOOK1 | Fusion gene ID: 12429 | Hgene | Tgene | Gene symbol | FAF1 | HOOK1 | Gene ID | 11124 | 51361 |
| Gene name | Fas associated factor 1 | hook microtubule tethering protein 1 | |
| Synonyms | CGI-03|HFAF1s|UBXD12|UBXN3A|hFAF1 | HK1 | |
| Cytomap | 1p32.3 | 1p32.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | FAS-associated factor 1Fas (TNFRSF6) associated factor 1TNFRSF6-associated factor 1UBX domain protein 3AUBX domain-containing protein 12UBX domain-containing protein 3A | protein Hook homolog 1h-hook1hHK1hook homolog 1 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9UNN5 | Q9UJC3 | |
| Ensembl transtripts involved in fusion gene | ENST00000396153, ENST00000371778, ENST00000545823, ENST00000472808, | ENST00000371208, ENST00000465876, ENST00000395561, | |
| Fusion gene scores | * DoF score | 15 X 10 X 8=1200 | 3 X 4 X 3=36 |
| # samples | 21 | 4 | |
| ** MAII score | log2(21/1200*10)=-2.51457317282976 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: FAF1 [Title/Abstract] AND HOOK1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | FAF1 | GO:0010942 | positive regulation of cell death | 15596450 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-EW-A3U0-01A | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000396153 | ENST00000371208 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| 5CDS-intron | ENST00000396153 | ENST00000465876 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| 5CDS-intron | ENST00000396153 | ENST00000395561 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| Frame-shift | ENST00000371778 | ENST00000371208 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| 5CDS-intron | ENST00000371778 | ENST00000465876 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| 5CDS-intron | ENST00000371778 | ENST00000395561 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| intron-3CDS | ENST00000545823 | ENST00000371208 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| intron-intron | ENST00000545823 | ENST00000465876 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| intron-intron | ENST00000545823 | ENST00000395561 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| intron-3CDS | ENST00000472808 | ENST00000371208 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| intron-intron | ENST00000472808 | ENST00000465876 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
| intron-intron | ENST00000472808 | ENST00000395561 | FAF1 | chr1 | 51210356 | - | HOOK1 | chr1 | 60330304 | + |
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FusionProtFeatures for FAF1_HOOK1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FAF1 | HOOK1 |
| Ubiquitin-binding protein (PubMed:19722279). Requiredfor the progression of DNA replication forks by targeting DNAreplication licensing factor CDT1 for degradation(PubMed:26842564). Potentiates but cannot initiate FAS-inducedapoptosis (By similarity). {ECO:0000250|UniProtKB:P54731,ECO:0000269|PubMed:19722279, ECO:0000269|PubMed:26842564}. | Required for spermatid differentiation. Probablyinvolved in the positioning of the microtubules of the manchetteand the flagellum in relation to the membrane skeleton (Bysimilarity). Component of the FTS/Hook/FHIP complex (FHF complex).The FHF complex may function to promote vesicle trafficking and/orfusion via the homotypic vesicular protein sorting complex (theHOPS complex) (PubMed:18799622). {ECO:0000250|UniProtKB:Q8BIL5,ECO:0000269|PubMed:18799622}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | FAF1 | chr1:51210356 | chr1:60330304 | ENST00000371778 | - | 6 | 20 | 1_57 | 153 | 651 | Domain | UBA |
| Hgene | FAF1 | chr1:51210356 | chr1:60330304 | ENST00000396153 | - | 5 | 19 | 1_57 | 153 | 651 | Domain | UBA |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >FAF1 | chr1:51210356 | chr1:60330304 | ENST00000371778 | - | 6 | 20 | 569_646 | 153 | 651 | Domain | UBX |
| Hgene | >FAF1 | chr1:51210356 | chr1:60330304 | ENST00000396153 | - | 5 | 19 | 569_646 | 153 | 651 | Domain | UBX |
| Tgene | HOOK1 | chr1:51210356 | chr1:60330304 | ENST00000371208 | + | 15 | 22 | 169_434 | 542 | 729 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | HOOK1 | chr1:51210356 | chr1:60330304 | ENST00000371208 | + | 15 | 22 | 477_658 | 542 | 729 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | HOOK1 | chr1:51210356 | chr1:60330304 | ENST00000371208 | + | 15 | 22 | 12_128 | 542 | 729 | Domain | Calponin-homology (CH) |
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FusionGeneSequence for FAF1_HOOK1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FAF1_ENST00000396153_chr1_51210356_-_HOOK1_ENST00000371208_chr1_60330304_+_340aa MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGETIPGPAFNPASHPASAPTSSSSSAFRPVMPS RQIVERQPRMLDFRVEYRDRNVDVVLEDTCTVGEIKQILENELQIPVSKMLLKGWKTGDVEDSSSKLKQKLEAHMEKLTEVHEELQKKQE LIEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRD |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FAF1_ENST00000396153_chr1_51210356_-_HOOK1_ENST00000371208_chr1_60330304_+_1020nt ATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGCTT GAACAAAATAATTGGGACTTAGTGGCAGCTATCAATGGTGTAATACCACAGGAAAATGGCATTCTACAAAGTGAATATGGAGGTGAGACC ATACCAGGACCTGCATTTAATCCAGCAAGTCATCCAGCTTCAGCTCCTACTTCCTCTTCTTCTTCAGCGTTTCGACCTGTAATGCCATCC AGGCAGATTGTAGAAAGGCAACCTCGGATGCTGGACTTCAGGGTTGAATACAGAGACAGAAATGTTGATGTGGTACTTGAAGACACCTGT ACTGTTGGAGAGATTAAACAGATTCTAGAAAATGAACTTCAGATACCTGTGTCCAAAATGCTGTTAAAAGGCTGGAAGACGGGAGATGTG GAAGACAGTTCCAGCAAATTAAAGCAGAAGTTGGAAGCTCATATGGAAAAACTCACAGAGGTCCATGAAGAATTACAGAAGAAACAAGAA CTCATTGAAGATCTTCAGCCAGATATAAATCAAAATGTACAAAAGATCAATGAACTTGAAGCTGCTCTTCAGAAGAAAGATGAAGATATG AAAGCAATGGAGGAAAGATATAAAATGTACTTGGAGAAAGCCAGAAATGTAATAAAAACTTTGGATCCCAAGTTAAATCCAGCATCAGCT GAAATAATGCTACTAAGAAAGCAGTTGGCAGAGAAAGAGAGAAGAATTGAGATTCTGGAGAGTGAATGCAAAGTAGCAAAATTCCGTGAT TATGAAGAAAAACTCATTGTTTCTGCGTGGTATAATAAGAGTCTAGCATTCCAGAAACTGGGGATGGAATCTAGACTTGTGAGCGGCGGT GGTGCCTGCAGTGACACTGGTGCGTGCACTCCTGCGCGGTCTTTCTTAGCGCAGCAACGGCACATCACCAACACCAGAAGAAATCTCTCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FAF1_ENST00000396153_chr1_51210356_-_HOOK1_ENST00000371208_chr1_60330304_+_4885nt AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGC TTGAACAAAATAATTGGGACTTAGTGGCAGCTATCAATGGTGTAATACCACAGGAAAATGGCATTCTACAAAGTGAATATGGAGGTGAGA CCATACCAGGACCTGCATTTAATCCAGCAAGTCATCCAGCTTCAGCTCCTACTTCCTCTTCTTCTTCAGCGTTTCGACCTGTAATGCCAT CCAGGCAGATTGTAGAAAGGCAACCTCGGATGCTGGACTTCAGGGTTGAATACAGAGACAGAAATGTTGATGTGGTACTTGAAGACACCT GTACTGTTGGAGAGATTAAACAGATTCTAGAAAATGAACTTCAGATACCTGTGTCCAAAATGCTGTTAAAAGGCTGGAAGACGGGAGATG TGGAAGACAGTTCCAGCAAATTAAAGCAGAAGTTGGAAGCTCATATGGAAAAACTCACAGAGGTCCATGAAGAATTACAGAAGAAACAAG AACTCATTGAAGATCTTCAGCCAGATATAAATCAAAATGTACAAAAGATCAATGAACTTGAAGCTGCTCTTCAGAAGAAAGATGAAGATA TGAAAGCAATGGAGGAAAGATATAAAATGTACTTGGAGAAAGCCAGAAATGTAATAAAAACTTTGGATCCCAAGTTAAATCCAGCATCAG CTGAAATAATGCTACTAAGAAAGCAGTTGGCAGAGAAAGAGAGAAGAATTGAGATTCTGGAGAGTGAATGCAAAGTAGCAAAATTCCGTG ATTATGAAGAAAAACTCATTGTTTCTGCGTGGTATAATAAGAGTCTAGCATTCCAGAAACTGGGGATGGAATCTAGACTTGTGAGCGGCG GTGGTGCCTGCAGTGACACTGGTGCGTGCACTCCTGCGCGGTCTTTCTTAGCGCAGCAACGGCACATCACCAACACCAGAAGAAATCTCT CTGTTAAAGTCCCTGCTACAACATCTGATTAAACTGCAAAAAAAACAAAACAAAACAAAAAAACCACATAAAATAGAAGTGTCCTTAAAA TATTTTGTACCTTTCAACTAACTACCAGATTGAAAAAGAGTTTATGATGCGGGATATCAGGTATTTTAAAATCAACATGCATCAAATTAA TTTTGCCAGTTGACTTTAAAAACAAATTATAGAATTAGCCATCTCTCTGAGGGAGCACATTTGAATAATTGGAGATGCAGTTATACACAC ATTTCAAACAAACATTTGTCTTTTGAGAGTATTATAATTTCAAATTGGCCTTGTATATTTTAGTTAAATGTTTTCAGTTGTATTAGTAAC TTAATTAATTTTCAATAGCTATTCAGTAATACTTAATCTTAGAACATTAATTGGATTTGTTTAATCTTTTTTTGTTTTTTGTTGATTTAT ATGAAAACAGTCTTGAGGCAGGGACATGGAGAACTATGCAAGGGTGATTTCTTTGACTTAATATATACAAGGCTTTACTTCTGTCCCCTA ATTCTTCCATTGAATGTGTACCTCTACCTTGTCATGTCATGGAAGATACAACATTTGGAAGATCTGACAATTGGAATGACTTTGGAATAA TAAAATTGACTAATTGGAAATTTTGCATATTCTGAAAATCTAATCTCATAGTTCTAATTTGTACCTATGGCAAATAAGGGCTTCTGGACA TCATGTTTAAAATGTTAAGCATAAGAAATAAACTGACATTTGTAATAGGTGACTTTCTGATGGAAAGCAAGCTATATATATATATATATA TATATATATATATATATATATACTTTTTGTGAAATGTCTATATACTTTTTAAGGTAATTAATGAAGATTTCAGTTATTGCTTTTAAGCAT AAAGTTGTATTTAGCTTCTGCTGAAAAATTGTATCATATAATAATTTTGCTTCATTGAAAAGGGATGTTGCAGTGATGAAACAAGGTGGG ATCAGTTTGATTTTGTTTACTTATTAAGGAGTTTATCTTGGGCTCAGTTTGTGGTATTCAGTTCGTTTCTGCCCAAAGCTCTTATTTTCA GAGGTGTTACTTTTGAACTTTTGGGGTCATTTTTAAAAGTTAGCACTTTTGAATTTTAGTTGTGTTAAATATGTGCTGTCGTATATCATA GCCATGAGCCATATATGACAATTTAAATTTAATTAATTATAAACTCAGTCTCTTGGTTGCACCAGCCACATTTCAGATGCTCAATAGCCA CATGTGGCTAGTGGGTACCATATTGGACAGGGCAGCTATAGAATATTTCCATCATTGCAGAAAGTTCTATTGGATAGTACCATAATCTTT TTATAGTAACTTGGAAATACTATTTGATATTAGATGTTAGACCACAAAAAGAAGAAAAATGTTAGGACTATTTCAGATATAAAAAGGAAC TGAATTGTGACATAATTAGCATCTTACATTCCATACAGTTGAATACCTTATGCTGTGACAACCATAGTTAATCATTTCAGTGCTGTTCAA CATACATACCTATCAGCAGTGTGTTTAGACCAGGGGTCTGCAAACTTTCTGTGAATGGACAAAGAGTAAATACTTTAGTAAATGTCTTAG GCTTTGTGGCCTACATGATCTTTGTTGCAAGTACTCAACTCTGCCATTATAGAGTTAAAGCAGCCATACACAATATATAAACAAAATGGG CATAGTTGTATTTCAGTAAAACTTTATTTACAAAGACAGGCGGTAGGCCAGATTTGGCTTGCATGCTGTAGAGCTGTGGTCTAAATTTTA TTCATAGACTTTCTTTGCAAATACAGTGTGAGTATTGTTCCATTTACAGTATTATTATTTTTTAGATACCTGGTTTTTAGATTCTTGCCT GGTAACTTTTTACTGAAAATACAAGAATTTCGTACTGCATTTGCATCTCCGAGATTAGGGAGCACCTGTCAGGATATGTTGTTCTATCAG GGTTACTTCTGTTGACTACCTCTTAGATTTTGATACAGTTATATTGTTGAGTTTCATTTTCATATATTCTTGTAGTGTCTGCTTGCCTGT GACTTCTGGTAAAATAAAATAAGCCTTTGAAAATATTTTAGCATGGTATTTAACATTTTCTAAATATTATGGCATTTTGACATATTTTAG TCAGCGAAGACATCTGCCCCTTTGGTGTTTCTACTTGCTTATGATTGAGATTTTACAAGCCCTTCAAACTCCGTTTTAAAGGAATTTATT GTAAAACATTAACTTTAATAAATTAGTGTTTTCACAGATCAGATCATTATACTTGGAACTTCTAAATCATGCAATTTCTGAATAAGGACA TAAGGCTAGATTCATTTTTCTTAATAGAGAAAAAGGAAATTTCTGATTTATCACTTTTCTAGTTGATAAGTAGGATTCAAAACGTTTGAT ATGTAAGTATTTATATAAGACTAATGTAATTTAAAGTTCTGTATTATTGTGATTAATCATACAGAAATTCAGGAACTGATCAGAAGTGAG ATTCTTTTCCACATCTGGTTAATGTAGTGAGTTGACACCCTGTGGGTGGTAAAGCATTATAAACATTTCATCTTGAACCATGATTTATAC ACATCTGTGTTATAAGGGAGGCTTGAGTACATATACCAATGAAGAGATATTCAGCATTTGTCTATTTGATAAGGAATTAAATGTCCTAGT GATTATAAAGTAAAACCACAGACCAATTTGCAAATGATCTTCAATGTTAAGCACTTGCTCTAAGATTAAAATTCCTTTTCTTTTTAAGGT TAAGGGTGTGTACGTATGGCAGTGATGTCTATGTTGAGATTAACTTATGTATTGAGGAAAATTTGAAGTTTATTTTTTCGATGAATAAGG CTGTCAAATGATTTAGTATAGATTAATGACATCTTTTTTAGAAATATTAAAGTGAGTATTCCTCATTATGTCATCATTTCTGATAATTAG AGTGCTAATTTGAATGTTAGATAATGTTTCCACATCTATACCTATTTCTTTCTAGGGCACTTCTGACCCTGGGGCTTGGGGATGGCCTTT AGGCCACAGTAGTGTCTGTGTTAAGTTCACTAAATGTGTATTTAATGAGAAACATTCCTATGTAAAAATGTGTGTATGTGAACGTATGCA TACATTTTTATTGTGCACCTGTACATTGTGAAGAAGTAGTTTGGAAATTTGTAAAGCACAAACCATAAAAGAGTGTGGAGTTATTAAATG ATGTAGCACAAATGTAATGTTTAGCTTATAAAAGGTCCTTTCTATTTTCTATGGCAAAGACTTTGACACTTGAAAAATAAAACCAATATT TGATTTATTTTTGTAAGTATTTAGGATATTATTTTAAATAAATGATTGTCCATTATCAATATAATAGTTGTGAAATGATTTAAGTAAATA |
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FusionGenePPI for FAF1_HOOK1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FAF1 | ASCC2, FAS, CSNK2B, G3BP1, RAE1, CASP8, CTNNB1, VCP, NPLOC4, UFD1L, CUL1, CUL2, CUL3, UBR1, HIF1A, ALPP, VCPIP1, SKP1, FBXW11, KLHL22, KBTBD7, WDR26, AMFR, UBR2, UBR4, PJA2, CDC73, TAF1D, RAP1B, UROD, TK1, ANXA1, DNAJB11, CDKN1A, TNNT1, SIRT6, HSD17B10, RCC1, NR1H2, ANXA7, TSC22D1, NR4A1, ITGB1BP1, IGF2, RAD23A, BTRC, NGLY1, UBC, HSPA4, RELA, HSPA8, FADD, IKBKB, NLRP3, NLRP2, NLRP7, NLRP12, NUDT21, SKIL, CARM1, CARS, FAM114A1, FARSB, GART, HIRIP3, HIST1H4A, HSPH1, ILK, PLOD2, PPM1G, PPP2R5C, PRMT3, PUF60, RANBP3, RPL24, SAMHD1, SEC23A, SET, SF1, SWAP70, TLN1, TROVE2, UGP2, XPO7, VAPA, VAPB, UBL4A, ASNA1, GET4, BAG6, RPN2, DDOST, FAF1, CD40, MAGIX, TCEAL1, CBX3, DNAJA1, ZC3H15, NTRK1, RAP1A, CDT1, IPO5, WDR24, YTHDF1, CDC5L, KCTD10, YTHDF3, WDR59, MMAB, NUP98, MYCBP2, USP11, NSFL1C, UBXN7, UBXN1, ASPSCR1, HSPA2, MIOS, UBXN6, BTBD9, KCTD13, TNFAIP1, UBXN2B, BHLHA15, CHCHD10, CLEC3A, PRCC, TRIM25, XIAP | HOOK1 | ZNF250, AKTIP, CDC5L, HOOK2, HOOK3, HOOK1, FAM160A2, VPS16, VPS18, VPS39, VPS41, VCP, CDK4, LMO2, USP2, TFIP11, TBC1D7, SYCE1, ZNF785, LRRC29, TRAK2, TNFSF13B, RABGGTB, HERC2, AARSD1, SELENBP1, NCAPH2, CDC16, C6orf141, ALOXE3, CRYL1, TRIP11 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FAF1_HOOK1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FAF1_HOOK1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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