|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 12114 |
FusionGeneSummary for ESYT1_MED14 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ESYT1_MED14 | Fusion gene ID: 12114 | Hgene | Tgene | Gene symbol | ESYT1 | MED14 | Gene ID | 23344 | 9282 |
| Gene name | extended synaptotagmin 1 | mediator complex subunit 14 | |
| Synonyms | FAM62A|MBC2 | CRSP150|CRSP2|CSRP|CXorf4|DRIP150|EXLM1|RGR1|TRAP170 | |
| Cytomap | 12q13.2 | Xp11.4 | |
| Type of gene | protein-coding | protein-coding | |
| Description | extended synaptotagmin-1extended synaptotagmin like protein 1extended synaptotagmin protein 1family with sequence similarity 62 (C2 domain containing), member Amembrane-bound C2 domain-containing protein | mediator of RNA polymerase II transcription subunit 14ARC150CRSP complex subunit 2RGR1 homologactivator-recruited cofactor 150 kDa componentcofactor required for Sp1 transcriptional activation, subunit 2 (150kD)hRGR1human homolog of yeast RGR1thyr | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9BSJ8 | O60244 | |
| Ensembl transtripts involved in fusion gene | ENST00000394048, ENST00000267113, ENST00000541590, ENST00000550878, | ENST00000324817, ENST00000496531, | |
| Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 1 X 1 X 1=1 |
| # samples | 3 | 1 | |
| ** MAII score | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ESYT1 [Title/Abstract] AND MED14 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | MED14 | GO:0006367 | transcription initiation from RNA polymerase II promoter | 12218053 |
| Tgene | MED14 | GO:0030518 | intracellular steroid hormone receptor signaling pathway | 11867769 |
| Tgene | MED14 | GO:0030521 | androgen receptor signaling pathway | 12218053 |
| Tgene | MED14 | GO:0045893 | positive regulation of transcription, DNA-templated | 10198638 |
| Tgene | MED14 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 12037571 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-86-7954-01A | ESYT1 | chr12 | 56532797 | + | MED14 | chrX | 40514312 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000394048 | ENST00000324817 | ESYT1 | chr12 | 56532797 | + | MED14 | chrX | 40514312 | - |
| 5CDS-intron | ENST00000394048 | ENST00000496531 | ESYT1 | chr12 | 56532797 | + | MED14 | chrX | 40514312 | - |
| In-frame | ENST00000267113 | ENST00000324817 | ESYT1 | chr12 | 56532797 | + | MED14 | chrX | 40514312 | - |
| 5CDS-intron | ENST00000267113 | ENST00000496531 | ESYT1 | chr12 | 56532797 | + | MED14 | chrX | 40514312 | - |
| In-frame | ENST00000541590 | ENST00000324817 | ESYT1 | chr12 | 56532797 | + | MED14 | chrX | 40514312 | - |
| 5CDS-intron | ENST00000541590 | ENST00000496531 | ESYT1 | chr12 | 56532797 | + | MED14 | chrX | 40514312 | - |
| 3UTR-3CDS | ENST00000550878 | ENST00000324817 | ESYT1 | chr12 | 56532797 | + | MED14 | chrX | 40514312 | - |
| 3UTR-intron | ENST00000550878 | ENST00000496531 | ESYT1 | chr12 | 56532797 | + | MED14 | chrX | 40514312 | - |
Top |
FusionProtFeatures for ESYT1_MED14 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ESYT1 | MED14 |
| Binds glycerophospholipids in a barrel-like domain andmay play a role in cellular lipid transport (By similarity). Bindscalcium (via the C2 domains) and translocates to sites of contactbetween the endoplasmic reticulum and the cell membrane inresponse to increased cytosolic calcium levels. Helps tether theendoplasmic reticulum to the cell membrane and promotes theformation of appositions between the endoplasmic reticulum and thecell membrane. {ECO:0000250, ECO:0000269|PubMed:23791178,ECO:0000269|PubMed:24183667}. | Component of the Mediator complex, a coactivatorinvolved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge toconvey information from gene-specific regulatory proteins to thebasal RNA polymerase II transcription machinery. Mediator isrecruited to promoters by direct interactions with regulatoryproteins and serves as a scaffold for the assembly of a functionalpreinitiation complex with RNA polymerase II and the generaltranscription factors. {ECO:0000269|PubMed:15340088,ECO:0000269|PubMed:15625066, ECO:0000269|PubMed:16595664}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 91_116 | 874 | 1115 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 91_116 | 864 | 1105 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 91_116 | 874 | 975 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 135_313 | 874 | 1115 | Domain | SMP-LTD |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 316_417 | 874 | 1115 | Domain | C2 1 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 465_558 | 874 | 1115 | Domain | C2 2 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 634_735 | 874 | 1115 | Domain | C2 3 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 785_877 | 874 | 1115 | Domain | C2 4 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 135_313 | 864 | 1105 | Domain | SMP-LTD |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 316_417 | 864 | 1105 | Domain | C2 1 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 465_558 | 864 | 1105 | Domain | C2 2 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 634_735 | 864 | 1105 | Domain | C2 3 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 135_313 | 874 | 975 | Domain | SMP-LTD |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 316_417 | 874 | 975 | Domain | C2 1 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 465_558 | 874 | 975 | Domain | C2 2 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 634_735 | 874 | 975 | Domain | C2 3 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 785_877 | 874 | 975 | Domain | C2 4 |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 1_38 | 874 | 1115 | Topological domain | Cytoplasmic |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 60_62 | 874 | 1115 | Topological domain | Lumenal |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 1_38 | 864 | 1105 | Topological domain | Cytoplasmic |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 60_62 | 864 | 1105 | Topological domain | Lumenal |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 1_38 | 874 | 975 | Topological domain | Cytoplasmic |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 60_62 | 874 | 975 | Topological domain | Lumenal |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 39_59 | 874 | 1115 | Transmembrane | Helical |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 63_83 | 874 | 1115 | Transmembrane | Helical |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 39_59 | 864 | 1105 | Transmembrane | Helical |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 63_83 | 864 | 1105 | Transmembrane | Helical |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 39_59 | 874 | 975 | Transmembrane | Helical |
| Hgene | ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 63_83 | 874 | 975 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 1012_1015 | 874 | 1115 | Compositional bias | Note=Poly-Leu |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 924_935 | 874 | 1115 | Compositional bias | Note=Poly-Ser |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 1012_1015 | 864 | 1105 | Compositional bias | Note=Poly-Leu |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 924_935 | 864 | 1105 | Compositional bias | Note=Poly-Ser |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 1012_1015 | 874 | 975 | Compositional bias | Note=Poly-Leu |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 924_935 | 874 | 975 | Compositional bias | Note=Poly-Ser |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 972_1077 | 874 | 1115 | Domain | C2 5 |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 785_877 | 864 | 1105 | Domain | C2 4 |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 972_1077 | 864 | 1105 | Domain | C2 5 |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 972_1077 | 874 | 975 | Domain | C2 5 |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 1018_1025 | 874 | 1115 | Region | Required for phosphatidylinositol 4%2C5-bisphosphate-dependent location at the cell membrane |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 1018_1025 | 864 | 1105 | Region | Required for phosphatidylinositol 4%2C5-bisphosphate-dependent location at the cell membrane |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 1018_1025 | 874 | 975 | Region | Required for phosphatidylinositol 4%2C5-bisphosphate-dependent location at the cell membrane |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000267113 | + | 24 | 31 | 84_1104 | 874 | 1115 | Topological domain | Cytoplasmic |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000394048 | + | 24 | 31 | 84_1104 | 864 | 1105 | Topological domain | Cytoplasmic |
| Hgene | >ESYT1 | chr12:56532797 | chrX:40514312 | ENST00000541590 | + | 24 | 32 | 84_1104 | 874 | 975 | Topological domain | Cytoplasmic |
| Tgene | MED14 | chr12:56532797 | chrX:40514312 | ENST00000324817 | - | 27 | 31 | 1002_1165 | 1324 | 1455 | Compositional bias | Note=Pro-rich |
| Tgene | MED14 | chr12:56532797 | chrX:40514312 | ENST00000324817 | - | 27 | 31 | 1182_1186 | 1324 | 1455 | Motif | Note=LXXLL motif 2 |
| Tgene | MED14 | chr12:56532797 | chrX:40514312 | ENST00000324817 | - | 27 | 31 | 69_73 | 1324 | 1455 | Motif | Note=LXXLL motif 1 |
Top |
FusionGeneSequence for ESYT1_MED14 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ESYT1_ENST00000394048_chr12_56532797_+_MED14_ENST00000324817_chrX_40514312_-_995aa MERSPGEGPSPSPMDQPSAPSDPTDQPPAAHAKPDPGSGGQPAGPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYLG WRRVRDEKERSLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGSNPHLQTFT FTRVELGEKPLRIIGVKVHPGQRKEQILLDLNISYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPFVGAVSMFFIRRPTL DINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYA LVRLGTQTFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQASVLDDWFPLQGGQGQVHLRLEWLS LLSDAEKLEQVLQWNWGVSSRPDPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFRFFLQDPQSQE LDVQVKDDSRALTLGALTLPLARLLTAPELILDQWFQLSSSGPNSRLYMKLVMRILYLDSSEICFPTVPGCPGAWDVDSENPQRGSSVDA PPRPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEVEV FDKDLDKDDFLGRCKVRLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSIYMERAEDL PLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASFLIRKPHTESLELQFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLK SKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPP >In-frame_ESYT1_ENST00000267113_chr12_56532797_+_MED14_ENST00000324817_chrX_40514312_-_1005aa MERSPGEGPSPSPMDQPSAPSDPTDQPPAAHAKPDPGSGGQPAGPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYLG WRRVRDEKERSLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGSNPHLQTFT FTRVELGEKPLRIIGVKVHPGQRKEQILLDLNISYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPFVGAVSMFFIRRPTL DINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYA LVRLGTQTFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQASVLDDWFPLQGGQGQVHLRLEWLS LLSDAEKLEQVLQWNWGVSSRPDPPSAAILVVYLDRAQDLPMVTSELYPPQLKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFR FFLQDPQSQELDVQVKDDSRALTLGALTLPLARLLTAPELILDQWFQLSSSGPNSRLYMKLVMRILYLDSSEICFPTVPGCPGAWDVDSE NPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTS VPGQELEVEVFDKDLDKDDFLGRCKVRLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALL SIYMERAEDLPLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASFLIRKPHTESLELQFPDQATQLKWNVQFCLTIPPSAPPIA PPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVR >In-frame_ESYT1_ENST00000541590_chr12_56532797_+_MED14_ENST00000324817_chrX_40514312_-_1005aa MERSPGEGPSPSPMDQPSAPSDPTDQPPAAHAKPDPGSGGQPAGPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYLG WRRVRDEKERSLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGSNPHLQTFT FTRVELGEKPLRIIGVKVHPGQRKEQILLDLNISYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPFVGAVSMFFIRRPTL DINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYA LVRLGTQTFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQASVLDDWFPLQGGQGQVHLRLEWLS LLSDAEKLEQVLQWNWGVSSRPDPPSAAILVVYLDRAQDLPMVTSELYPPQLKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFR FFLQDPQSQELDVQVKDDSRALTLGALTLPLARLLTAPELILDQWFQLSSSGPNSRLYMKLVMRILYLDSSEICFPTVPGCPGAWDVDSE NPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTS VPGQELEVEVFDKDLDKDDFLGRCKVRLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALL SIYMERAEDLPLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASFLIRKPHTESLELQFPDQATQLKWNVQFCLTIPPSAPPIA PPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ESYT1_ENST00000394048_chr12_56532797_+_MED14_ENST00000324817_chrX_40514312_-_2985nt ATGGAGCGATCTCCAGGAGAGGGCCCCAGCCCCAGCCCCATGGACCAGCCCTCTGCTCCCTCCGACCCCACTGACCAGCCCCCCGCTGCT CACGCAAAGCCAGACCCAGGTTCTGGGGGCCAACCTGCTGGCCCTGGCGCGGCGGGTGAGGCCCTGGCGGTGCTGACTTCATTCGGGAGG CGGTTGCTGGTGCTGATACCTGTGTATTTGGCCGGGGCAGTGGGACTCAGCGTGGGTTTCGTGCTCTTCGGCCTCGCCCTCTACCTGGGC TGGCGCCGGGTCCGCGACGAGAAAGAACGGAGCCTTCGAGCAGCGAGGCAGCTACTGGACGACGAGGAGCAGCTCACTGCGAAAACTCTC TATATGAGTCATCGAGAGCTACCTGCCTGGGTCAGCTTCCCAGACGTGGAAAAGGCTGAATGGCTCAATAAGATTGTGGCCCAGGTCTGG CCCTTCCTGGGCCAGTATATGGAGAAGCTTCTGGCTGAAACTGTGGCTCCGGCTGTTAGGGGATCTAACCCCCATCTGCAAACATTTACA TTTACACGAGTGGAACTGGGTGAAAAGCCATTGCGCATCATTGGAGTCAAGGTTCACCCAGGTCAGAGAAAAGAGCAGATCCTGCTGGAC TTGAACATCAGCTATGTAGGTGATGTGCAGATTGATGTGGAAGTGAAGAAATATTTTTGCAAAGCAGGAGTCAAGGGCATGCAGCTACAT GGCGTTTTGCGGGTGATACTGGAGCCACTCATTGGGGACCTTCCCTTCGTGGGGGCTGTGTCAATGTTCTTCATCCGACGCCCGACCCTA GACATCAACTGGACAGGGATGACCAACCTGCTGGATATCCCAGGACTTAGCTCACTCTCTGACACCATGATCATGGACTCCATTGCTGCC TTCCTCGTGTTGCCCAACCGATTACTGGTGCCCCTTGTGCCTGACCTTCAAGATGTGGCTCAGTTGCGTTCCCCTCTGCCCAGGGGCATT ATTCGAATTCACCTGCTGGCTGCTCGAGGGCTGAGTTCCAAGGACAAATATGTGAAGGGCCTGATTGAGGGCAAGTCAGACCCATATGCA CTTGTGCGTTTGGGTACCCAGACATTCTGCAGTCGTGTCATTGATGAAGAACTCAACCCACAGTGGGGAGAGACTTATGAGGTGATGGTA CACGAGGTCCCAGGGCAGGAGATTGAAGTGGAGGTGTTCGACAAGGATCCAGATAAAGATGACTTTCTGGGCAGAATGAAGCTGGATGTA GGGAAGGTGTTACAGGCTAGCGTTCTGGATGATTGGTTCCCTCTACAAGGTGGGCAAGGCCAAGTTCACTTGAGGCTAGAATGGCTGTCA CTTTTGTCAGATGCAGAGAAACTGGAGCAGGTTCTACAGTGGAATTGGGGAGTCTCCTCTCGACCAGATCCCCCGTCAGCTGCCATCTTA GTTGTCTACCTGGATCGGGCCCAGGATCTTCCTCTGAAGAAGGGGAACAAGGAACCCAACCCTATGGTACAACTGTCAATTCAGGATGTG ACTCAGGAGAGCAAGGCTGTCTACAGTACCAACTGCCCAGTGTGGGAGGAAGCGTTCCGGTTCTTCCTACAAGACCCTCAAAGCCAGGAG CTCGATGTGCAAGTGAAGGATGATTCCAGGGCCCTGACTTTAGGAGCACTGACGCTGCCTCTGGCCCGCCTGCTGACTGCCCCAGAACTC ATCCTGGACCAGTGGTTCCAGCTCAGCAGCTCTGGTCCAAACTCCAGACTCTATATGAAACTAGTCATGAGGATCCTGTACTTGGATTCA TCAGAAATATGCTTCCCCACGGTGCCTGGTTGTCCTGGTGCTTGGGACGTGGACAGTGAGAATCCCCAGAGAGGCAGCAGTGTGGATGCC CCACCTCGACCCTGTCACACGACTCCTGATAGCCAGTTTGGGACTGAGCATGTGCTTCGGATCCATGTATTAGAGGCCCAGGACCTGATT GCCAAAGACCGTTTCTTGGGGGGACTGGTGAAGGGCAAGTCAGACCCCTATGTCAAACTAAAGTTGGCAGGACGAAGCTTCCGGAGCCAT GTTGTTCGGGAAGATCTCAATCCCCGCTGGAATGAGGTTTTTGAGGTGATCGTCACATCAGTTCCAGGCCAAGAGCTAGAGGTTGAAGTC TTTGACAAGGACTTGGACAAGGATGATTTTCTGGGCAGGTGTAAAGTGCGTCTCACCACAGTCTTAAACAGTGGCTTCCTTGATGAGTGG CTGACCCTGGAGGATGTCCCATCTGGCCGCCTGCACTTGCGCCTGGAGCGTCTCACCCCCCGTCCCACTGCTGCTGAGTTAGAGGAGGTG CTGCAGGTGAATAGTTTGATCCAGACTCAGAAGAGTGCGGAGCTGGCTGCGGCCCTGCTATCCATCTATATGGAGCGGGCAGAGGACCTC CCGCTGCGAAAAGGCACCAAGCACCTCAGCCCTTATGCTACTCTCACTGTGGGAGATAGTTCTCATAAAACCAAGACTATTTCGCAAACT TCAGCCCCTGTCTGGGATGAGAGTGCCTCCTTTCTCATCAGGAAACCACACACTGAGAGCCTAGAGTTGCAGTTCCCTGACCAAGCAACA CAGCTAAAATGGAATGTTCAGTTTTGCCTGACGATCCCTCCCAGCGCGCCGCCGATTGCACCTCCTGGGACGCCTGCTGTGGTGCTGAAA TCCAAAATGCTATTTTTTCTTCAACTAACTCAGAAAACATCGGTCCCTCCCCAAGAACCTGTTAGTATTATAGTTCCAATCATTTATGAC ATGGCTTCAGGTACAACCCAGCAGGCAGACATTCCCAGACAGCAGAACTCTTCTGTTGCTGCTCCCATGATGGTCAGCAACATTCTGAAG AGGTTTGCAGAGATGAATCCACCACGACAAGGTGAATGCACAATATTTGCAGCTGTTCGTGATTTAATGGCTAATCTTACACTGCCCCCT >In-frame_ESYT1_ENST00000267113_chr12_56532797_+_MED14_ENST00000324817_chrX_40514312_-_3015nt ATGGAGCGATCTCCAGGAGAGGGCCCCAGCCCCAGCCCCATGGACCAGCCCTCTGCTCCCTCCGACCCCACTGACCAGCCCCCCGCTGCT CACGCAAAGCCAGACCCAGGTTCTGGGGGCCAACCTGCTGGCCCTGGCGCGGCGGGTGAGGCCCTGGCGGTGCTGACTTCATTCGGGAGG CGGTTGCTGGTGCTGATACCTGTGTATTTGGCCGGGGCAGTGGGACTCAGCGTGGGTTTCGTGCTCTTCGGCCTCGCCCTCTACCTGGGC TGGCGCCGGGTCCGCGACGAGAAAGAACGGAGCCTTCGAGCAGCGAGGCAGCTACTGGACGACGAGGAGCAGCTCACTGCGAAAACTCTC TATATGAGTCATCGAGAGCTACCTGCCTGGGTCAGCTTCCCAGACGTGGAAAAGGCTGAATGGCTCAATAAGATTGTGGCCCAGGTCTGG CCCTTCCTGGGCCAGTATATGGAGAAGCTTCTGGCTGAAACTGTGGCTCCGGCTGTTAGGGGATCTAACCCCCATCTGCAAACATTTACA TTTACACGAGTGGAACTGGGTGAAAAGCCATTGCGCATCATTGGAGTCAAGGTTCACCCAGGTCAGAGAAAAGAGCAGATCCTGCTGGAC TTGAACATCAGCTATGTAGGTGATGTGCAGATTGATGTGGAAGTGAAGAAATATTTTTGCAAAGCAGGAGTCAAGGGCATGCAGCTACAT GGCGTTTTGCGGGTGATACTGGAGCCACTCATTGGGGACCTTCCCTTCGTGGGGGCTGTGTCAATGTTCTTCATCCGACGCCCGACCCTA GACATCAACTGGACAGGGATGACCAACCTGCTGGATATCCCAGGACTTAGCTCACTCTCTGACACCATGATCATGGACTCCATTGCTGCC TTCCTCGTGTTGCCCAACCGATTACTGGTGCCCCTTGTGCCTGACCTTCAAGATGTGGCTCAGTTGCGTTCCCCTCTGCCCAGGGGCATT ATTCGAATTCACCTGCTGGCTGCTCGAGGGCTGAGTTCCAAGGACAAATATGTGAAGGGCCTGATTGAGGGCAAGTCAGACCCATATGCA CTTGTGCGTTTGGGTACCCAGACATTCTGCAGTCGTGTCATTGATGAAGAACTCAACCCACAGTGGGGAGAGACTTATGAGGTGATGGTA CACGAGGTCCCAGGGCAGGAGATTGAAGTGGAGGTGTTCGACAAGGATCCAGATAAAGATGACTTTCTGGGCAGAATGAAGCTGGATGTA GGGAAGGTGTTACAGGCTAGCGTTCTGGATGATTGGTTCCCTCTACAAGGTGGGCAAGGCCAAGTTCACTTGAGGCTAGAATGGCTGTCA CTTTTGTCAGATGCAGAGAAACTGGAGCAGGTTCTACAGTGGAATTGGGGAGTCTCCTCTCGACCAGATCCCCCGTCAGCTGCCATCTTA GTTGTCTACCTGGATCGGGCCCAGGATCTTCCTATGGTGACCTCTGAATTGTACCCACCACAGCTGAAGAAGGGGAACAAGGAACCCAAC CCTATGGTACAACTGTCAATTCAGGATGTGACTCAGGAGAGCAAGGCTGTCTACAGTACCAACTGCCCAGTGTGGGAGGAAGCGTTCCGG TTCTTCCTACAAGACCCTCAAAGCCAGGAGCTCGATGTGCAAGTGAAGGATGATTCCAGGGCCCTGACTTTAGGAGCACTGACGCTGCCT CTGGCCCGCCTGCTGACTGCCCCAGAACTCATCCTGGACCAGTGGTTCCAGCTCAGCAGCTCTGGTCCAAACTCCAGACTCTATATGAAA CTAGTCATGAGGATCCTGTACTTGGATTCATCAGAAATATGCTTCCCCACGGTGCCTGGTTGTCCTGGTGCTTGGGACGTGGACAGTGAG AATCCCCAGAGAGGCAGCAGTGTGGATGCCCCACCTCGACCCTGTCACACGACTCCTGATAGCCAGTTTGGGACTGAGCATGTGCTTCGG ATCCATGTATTAGAGGCCCAGGACCTGATTGCCAAAGACCGTTTCTTGGGGGGACTGGTGAAGGGCAAGTCAGACCCCTATGTCAAACTA AAGTTGGCAGGACGAAGCTTCCGGAGCCATGTTGTTCGGGAAGATCTCAATCCCCGCTGGAATGAGGTTTTTGAGGTGATCGTCACATCA GTTCCAGGCCAAGAGCTAGAGGTTGAAGTCTTTGACAAGGACTTGGACAAGGATGATTTTCTGGGCAGGTGTAAAGTGCGTCTCACCACA GTCTTAAACAGTGGCTTCCTTGATGAGTGGCTGACCCTGGAGGATGTCCCATCTGGCCGCCTGCACTTGCGCCTGGAGCGTCTCACCCCC CGTCCCACTGCTGCTGAGTTAGAGGAGGTGCTGCAGGTGAATAGTTTGATCCAGACTCAGAAGAGTGCGGAGCTGGCTGCGGCCCTGCTA TCCATCTATATGGAGCGGGCAGAGGACCTCCCGCTGCGAAAAGGCACCAAGCACCTCAGCCCTTATGCTACTCTCACTGTGGGAGATAGT TCTCATAAAACCAAGACTATTTCGCAAACTTCAGCCCCTGTCTGGGATGAGAGTGCCTCCTTTCTCATCAGGAAACCACACACTGAGAGC CTAGAGTTGCAGTTCCCTGACCAAGCAACACAGCTAAAATGGAATGTTCAGTTTTGCCTGACGATCCCTCCCAGCGCGCCGCCGATTGCA CCTCCTGGGACGCCTGCTGTGGTGCTGAAATCCAAAATGCTATTTTTTCTTCAACTAACTCAGAAAACATCGGTCCCTCCCCAAGAACCT GTTAGTATTATAGTTCCAATCATTTATGACATGGCTTCAGGTACAACCCAGCAGGCAGACATTCCCAGACAGCAGAACTCTTCTGTTGCT GCTCCCATGATGGTCAGCAACATTCTGAAGAGGTTTGCAGAGATGAATCCACCACGACAAGGTGAATGCACAATATTTGCAGCTGTTCGT >In-frame_ESYT1_ENST00000541590_chr12_56532797_+_MED14_ENST00000324817_chrX_40514312_-_3015nt ATGGAGCGATCTCCAGGAGAGGGCCCCAGCCCCAGCCCCATGGACCAGCCCTCTGCTCCCTCCGACCCCACTGACCAGCCCCCCGCTGCT CACGCAAAGCCAGACCCAGGTTCTGGGGGCCAACCTGCTGGCCCTGGCGCGGCGGGTGAGGCCCTGGCGGTGCTGACTTCATTCGGGAGG CGGTTGCTGGTGCTGATACCTGTGTATTTGGCCGGGGCAGTGGGACTCAGCGTGGGTTTCGTGCTCTTCGGCCTCGCCCTCTACCTGGGC TGGCGCCGGGTCCGCGACGAGAAAGAACGGAGCCTTCGAGCAGCGAGGCAGCTACTGGACGACGAGGAGCAGCTCACTGCGAAAACTCTC TATATGAGTCATCGAGAGCTACCTGCCTGGGTCAGCTTCCCAGACGTGGAAAAGGCTGAATGGCTCAATAAGATTGTGGCCCAGGTCTGG CCCTTCCTGGGCCAGTATATGGAGAAGCTTCTGGCTGAAACTGTGGCTCCGGCTGTTAGGGGATCTAACCCCCATCTGCAAACATTTACA TTTACACGAGTGGAACTGGGTGAAAAGCCATTGCGCATCATTGGAGTCAAGGTTCACCCAGGTCAGAGAAAAGAGCAGATCCTGCTGGAC TTGAACATCAGCTATGTAGGTGATGTGCAGATTGATGTGGAAGTGAAGAAATATTTTTGCAAAGCAGGAGTCAAGGGCATGCAGCTACAT GGCGTTTTGCGGGTGATACTGGAGCCACTCATTGGGGACCTTCCCTTCGTGGGGGCTGTGTCAATGTTCTTCATCCGACGCCCGACCCTA GACATCAACTGGACAGGGATGACCAACCTGCTGGATATCCCAGGACTTAGCTCACTCTCTGACACCATGATCATGGACTCCATTGCTGCC TTCCTCGTGTTGCCCAACCGATTACTGGTGCCCCTTGTGCCTGACCTTCAAGATGTGGCTCAGTTGCGTTCCCCTCTGCCCAGGGGCATT ATTCGAATTCACCTGCTGGCTGCTCGAGGGCTGAGTTCCAAGGACAAATATGTGAAGGGCCTGATTGAGGGCAAGTCAGACCCATATGCA CTTGTGCGTTTGGGTACCCAGACATTCTGCAGTCGTGTCATTGATGAAGAACTCAACCCACAGTGGGGAGAGACTTATGAGGTGATGGTA CACGAGGTCCCAGGGCAGGAGATTGAAGTGGAGGTGTTCGACAAGGATCCAGATAAAGATGACTTTCTGGGCAGAATGAAGCTGGATGTA GGGAAGGTGTTACAGGCTAGCGTTCTGGATGATTGGTTCCCTCTACAAGGTGGGCAAGGCCAAGTTCACTTGAGGCTAGAATGGCTGTCA CTTTTGTCAGATGCAGAGAAACTGGAGCAGGTTCTACAGTGGAATTGGGGAGTCTCCTCTCGACCAGATCCCCCGTCAGCTGCCATCTTA GTTGTCTACCTGGATCGGGCCCAGGATCTTCCTATGGTGACCTCTGAATTGTACCCACCACAGCTGAAGAAGGGGAACAAGGAACCCAAC CCTATGGTACAACTGTCAATTCAGGATGTGACTCAGGAGAGCAAGGCTGTCTACAGTACCAACTGCCCAGTGTGGGAGGAAGCGTTCCGG TTCTTCCTACAAGACCCTCAAAGCCAGGAGCTCGATGTGCAAGTGAAGGATGATTCCAGGGCCCTGACTTTAGGAGCACTGACGCTGCCT CTGGCCCGCCTGCTGACTGCCCCAGAACTCATCCTGGACCAGTGGTTCCAGCTCAGCAGCTCTGGTCCAAACTCCAGACTCTATATGAAA CTAGTCATGAGGATCCTGTACTTGGATTCATCAGAAATATGCTTCCCCACGGTGCCTGGTTGTCCTGGTGCTTGGGACGTGGACAGTGAG AATCCCCAGAGAGGCAGCAGTGTGGATGCCCCACCTCGACCCTGTCACACGACTCCTGATAGCCAGTTTGGGACTGAGCATGTGCTTCGG ATCCATGTATTAGAGGCCCAGGACCTGATTGCCAAAGACCGTTTCTTGGGGGGACTGGTGAAGGGCAAGTCAGACCCCTATGTCAAACTA AAGTTGGCAGGACGAAGCTTCCGGAGCCATGTTGTTCGGGAAGATCTCAATCCCCGCTGGAATGAGGTTTTTGAGGTGATCGTCACATCA GTTCCAGGCCAAGAGCTAGAGGTTGAAGTCTTTGACAAGGACTTGGACAAGGATGATTTTCTGGGCAGGTGTAAAGTGCGTCTCACCACA GTCTTAAACAGTGGCTTCCTTGATGAGTGGCTGACCCTGGAGGATGTCCCATCTGGCCGCCTGCACTTGCGCCTGGAGCGTCTCACCCCC CGTCCCACTGCTGCTGAGTTAGAGGAGGTGCTGCAGGTGAATAGTTTGATCCAGACTCAGAAGAGTGCGGAGCTGGCTGCGGCCCTGCTA TCCATCTATATGGAGCGGGCAGAGGACCTCCCGCTGCGAAAAGGCACCAAGCACCTCAGCCCTTATGCTACTCTCACTGTGGGAGATAGT TCTCATAAAACCAAGACTATTTCGCAAACTTCAGCCCCTGTCTGGGATGAGAGTGCCTCCTTTCTCATCAGGAAACCACACACTGAGAGC CTAGAGTTGCAGTTCCCTGACCAAGCAACACAGCTAAAATGGAATGTTCAGTTTTGCCTGACGATCCCTCCCAGCGCGCCGCCGATTGCA CCTCCTGGGACGCCTGCTGTGGTGCTGAAATCCAAAATGCTATTTTTTCTTCAACTAACTCAGAAAACATCGGTCCCTCCCCAAGAACCT GTTAGTATTATAGTTCCAATCATTTATGACATGGCTTCAGGTACAACCCAGCAGGCAGACATTCCCAGACAGCAGAACTCTTCTGTTGCT GCTCCCATGATGGTCAGCAACATTCTGAAGAGGTTTGCAGAGATGAATCCACCACGACAAGGTGAATGCACAATATTTGCAGCTGTTCGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ESYT1_ENST00000394048_chr12_56532797_+_MED14_ENST00000324817_chrX_40514312_-_6749nt ATCTTGGCCTTCGGGCCCAATCAGGGAGGCCCTACCTATCCGAAACCCGGTCCGTTCCCCGCGGAAGAGGGGTGGAGTTTCAACCTTTTA ACTCCACCTTGGTCTGTGCAGCGCGGACCAACCCAAATCGCCAGAAAGGAGGGGCGTGGCTTGAAGTCCCCTCCTCCATCCCGGGGATCA CGTTTTGCCTGGGGGAGCTGATCGCAAGACTAGGCAACCTCCAGCCAGTCCCTGGGTCGGGCGGATCCTCCCAGAGGTGGCACAATGGAG CGATCTCCAGGAGAGGGCCCCAGCCCCAGCCCCATGGACCAGCCCTCTGCTCCCTCCGACCCCACTGACCAGCCCCCCGCTGCTCACGCA AAGCCAGACCCAGGTTCTGGGGGCCAACCTGCTGGCCCTGGCGCGGCGGGTGAGGCCCTGGCGGTGCTGACTTCATTCGGGAGGCGGTTG CTGGTGCTGATACCTGTGTATTTGGCCGGGGCAGTGGGACTCAGCGTGGGTTTCGTGCTCTTCGGCCTCGCCCTCTACCTGGGCTGGCGC CGGGTCCGCGACGAGAAAGAACGGAGCCTTCGAGCAGCGAGGCAGCTACTGGACGACGAGGAGCAGCTCACTGCGAAAACTCTCTATATG AGTCATCGAGAGCTACCTGCCTGGGTCAGCTTCCCAGACGTGGAAAAGGCTGAATGGCTCAATAAGATTGTGGCCCAGGTCTGGCCCTTC CTGGGCCAGTATATGGAGAAGCTTCTGGCTGAAACTGTGGCTCCGGCTGTTAGGGGATCTAACCCCCATCTGCAAACATTTACATTTACA CGAGTGGAACTGGGTGAAAAGCCATTGCGCATCATTGGAGTCAAGGTTCACCCAGGTCAGAGAAAAGAGCAGATCCTGCTGGACTTGAAC ATCAGCTATGTAGGTGATGTGCAGATTGATGTGGAAGTGAAGAAATATTTTTGCAAAGCAGGAGTCAAGGGCATGCAGCTACATGGCGTT TTGCGGGTGATACTGGAGCCACTCATTGGGGACCTTCCCTTCGTGGGGGCTGTGTCAATGTTCTTCATCCGACGCCCGACCCTAGACATC AACTGGACAGGGATGACCAACCTGCTGGATATCCCAGGACTTAGCTCACTCTCTGACACCATGATCATGGACTCCATTGCTGCCTTCCTC GTGTTGCCCAACCGATTACTGGTGCCCCTTGTGCCTGACCTTCAAGATGTGGCTCAGTTGCGTTCCCCTCTGCCCAGGGGCATTATTCGA ATTCACCTGCTGGCTGCTCGAGGGCTGAGTTCCAAGGACAAATATGTGAAGGGCCTGATTGAGGGCAAGTCAGACCCATATGCACTTGTG CGTTTGGGTACCCAGACATTCTGCAGTCGTGTCATTGATGAAGAACTCAACCCACAGTGGGGAGAGACTTATGAGGTGATGGTACACGAG GTCCCAGGGCAGGAGATTGAAGTGGAGGTGTTCGACAAGGATCCAGATAAAGATGACTTTCTGGGCAGAATGAAGCTGGATGTAGGGAAG GTGTTACAGGCTAGCGTTCTGGATGATTGGTTCCCTCTACAAGGTGGGCAAGGCCAAGTTCACTTGAGGCTAGAATGGCTGTCACTTTTG TCAGATGCAGAGAAACTGGAGCAGGTTCTACAGTGGAATTGGGGAGTCTCCTCTCGACCAGATCCCCCGTCAGCTGCCATCTTAGTTGTC TACCTGGATCGGGCCCAGGATCTTCCTCTGAAGAAGGGGAACAAGGAACCCAACCCTATGGTACAACTGTCAATTCAGGATGTGACTCAG GAGAGCAAGGCTGTCTACAGTACCAACTGCCCAGTGTGGGAGGAAGCGTTCCGGTTCTTCCTACAAGACCCTCAAAGCCAGGAGCTCGAT GTGCAAGTGAAGGATGATTCCAGGGCCCTGACTTTAGGAGCACTGACGCTGCCTCTGGCCCGCCTGCTGACTGCCCCAGAACTCATCCTG GACCAGTGGTTCCAGCTCAGCAGCTCTGGTCCAAACTCCAGACTCTATATGAAACTAGTCATGAGGATCCTGTACTTGGATTCATCAGAA ATATGCTTCCCCACGGTGCCTGGTTGTCCTGGTGCTTGGGACGTGGACAGTGAGAATCCCCAGAGAGGCAGCAGTGTGGATGCCCCACCT CGACCCTGTCACACGACTCCTGATAGCCAGTTTGGGACTGAGCATGTGCTTCGGATCCATGTATTAGAGGCCCAGGACCTGATTGCCAAA GACCGTTTCTTGGGGGGACTGGTGAAGGGCAAGTCAGACCCCTATGTCAAACTAAAGTTGGCAGGACGAAGCTTCCGGAGCCATGTTGTT CGGGAAGATCTCAATCCCCGCTGGAATGAGGTTTTTGAGGTGATCGTCACATCAGTTCCAGGCCAAGAGCTAGAGGTTGAAGTCTTTGAC AAGGACTTGGACAAGGATGATTTTCTGGGCAGGTGTAAAGTGCGTCTCACCACAGTCTTAAACAGTGGCTTCCTTGATGAGTGGCTGACC CTGGAGGATGTCCCATCTGGCCGCCTGCACTTGCGCCTGGAGCGTCTCACCCCCCGTCCCACTGCTGCTGAGTTAGAGGAGGTGCTGCAG GTGAATAGTTTGATCCAGACTCAGAAGAGTGCGGAGCTGGCTGCGGCCCTGCTATCCATCTATATGGAGCGGGCAGAGGACCTCCCGCTG CGAAAAGGCACCAAGCACCTCAGCCCTTATGCTACTCTCACTGTGGGAGATAGTTCTCATAAAACCAAGACTATTTCGCAAACTTCAGCC CCTGTCTGGGATGAGAGTGCCTCCTTTCTCATCAGGAAACCACACACTGAGAGCCTAGAGTTGCAGTTCCCTGACCAAGCAACACAGCTA AAATGGAATGTTCAGTTTTGCCTGACGATCCCTCCCAGCGCGCCGCCGATTGCACCTCCTGGGACGCCTGCTGTGGTGCTGAAATCCAAA ATGCTATTTTTTCTTCAACTAACTCAGAAAACATCGGTCCCTCCCCAAGAACCTGTTAGTATTATAGTTCCAATCATTTATGACATGGCT TCAGGTACAACCCAGCAGGCAGACATTCCCAGACAGCAGAACTCTTCTGTTGCTGCTCCCATGATGGTCAGCAACATTCTGAAGAGGTTT GCAGAGATGAATCCACCACGACAAGGTGAATGCACAATATTTGCAGCTGTTCGTGATTTAATGGCTAATCTTACACTGCCCCCTGGTGGG CGTCCATAGACACTATTGTTTTTAAACCAGGAAGGCTGACAGATGAGACAACAAAAAAAATCTGAATTCAGCCTTCAGTTTAAAAAAGGA AAAGGACTTTTTTTTTAAACTTTAAGAGCTAAATATTCTAAACTGGCAAAAATTTTCAGGGTGCACTTCTTTCATCAAAATGATCATCCA TCTTTTGTATAATGAACTTGTATAGTGTGTTTAAATGGGACACATTTCAAAGGAAATAAATCAGTGTCCGTTTGCCAGTAATAAATTTAA TATTCTGTTTTATACTATAAAGTTATGAAAATGCCAAACTTGTTTATTTAATTGTTTTCTTATGTTTTGGGTGTAATAGTCCTTTTTTGG TTTTTGTTTTGTTTTTTAAGGCAGGTCTGTCATTTTTGAATACTGTAAAACTGTGATAAACTTTATATTGAAGCTGTATTTTAATATGAC CGCTTTGAATCCTTACATGAAATGTTCTGGGAGTTGTTATAAACACACCCCAAGGAAGCAATATTTAATAAAACTAGGTCAAAAACAAAA CAAAACAGTGACACTCACTTGTGTGTATATAAACTCTAGAGACATCTTAGGCCCTCCCTTCATCTTTAACCTGGTGGATGGAGCCAGTTA TTAATTTATAATAATACATGTCTGAAATTTGACCAAAAACATCTTCTTTATGTCAAGGTTAATATATTTTCTTCAGACATTCCTAACTTG ACTAGTGGTTAACATTTAGCACCTTGGTTGTCTTTCAATATATAGGATTTGGGTGAAAAATAAGGAACTTAGTCTTTGAGAAGGGACAGT ATGTGGTTCGTATTGATCAAGGATCCCAAATAATGCAATCATTCTCATCTGTTGAGGATGTGGGAACTTTTCTGTCAGGAAAATTTAGTT TACAGAATACTTCTGCATACAACATTAATTAGGAAACAAAGAACTTTAATGCTGTACCTCTGCATGAAGTTTCTGTGAGCTTTCTTTATC TTGCTTAACTTATCCTCCTTTCCTTCCCCACCAAAATTGGGATTGTTCTAAACAATTTCAATTTAATTCATTGTCAACAAAACGATAGAA TGTTTTGCTTGGAAGAAACCTGGTCCATTCCCCTCATTGTGAAGAATCCCGAATCCTGGGCCTGTCCAGGGTCAAATGGAGTTTTTGGTA TTAATACATCTCTGCAGGGTTTCTTTTTGGAGCACTGTGCTGTCTTTCCTAGTCAGTCAGGGACTTTTTTAAGCTTCAAAGAACATGGTC TGATGCAAAGGTCTTCTACCGACTTCATGGTATTTAGGAAAAATTTTTAAGTGATAATACCATGCCGAGTTACCTGGTCACTGTAATACT GGTTCTCCATTAAAATGTAGATGCTTTGTCTAATTCCACTTCAAGATGATTTAATTGAGCTTCTATAACTATCAACTATCAAATTCTAGT TTCAAGTATCTCACTGTACCTATATCATATCTGTTCTCAACTTTGTTTGATTCTCCACTCATTTTCAATCAGAGTTGAAGCCTTCTTTGC CTTTCTTCTTTGTCTTATTTCTGCCTTCATCTCCCACTTCTCACCCAACTCTGCCACTGTTCAGGAGCAGTTGACTAAACTTTTATCCTT CCTTTAACTTAATCTTTTTATCCTTCTGTTTTTAGTTCTTACAGTGGTAATCACATCAGTTTGGCAATCTAAGATGTCTTTATCAAGGGT CAGCCCTTTTCTATTTGGAGCTGAATCTTTTCTTTCATGTAGAAATCTACATGTATATACAAGAAATGTATTTTTATCTGCAGGATAATA TTGTTTCAAATAATTTTATTAAGAGTTAACTTTTTAGGTATTTTCCCTTTTAATGTGGTTTTGAAATGTTAATTGCATTTTTACACATGA TGCATTCAGTGGACACTCTTTTTTCCTAATTATAACTCATCTCTGAATGCATTGTGCCAATCAAGAGTAAGATAGGATTCAGTGCGCAAA ATTTGCTTTTGATGCTTATTAAGAGTAAACCCATGAATTTGAATTTTTATATTATGCTTGGTACTTGGAATTGATATATACCTTATTAAA GCTTGAAAACATTTAGCATTTGAATAGTAAGTTTCATCACAAATCATGTCTTTTGCCTCTTTTGTTACCCAGGTTCGATCAAGGGGACTG GATGCCCAAGTGATTTTCTCTAATAATCGGGTTGGGACTTAACTTTAAGGTGTTTTCAATGTGATTTTAGTATTTACAGTAATAAATAAA ATTTATACAAAGTTTCAGAGAACTACCAACTCTCTAGTTAATTTTGATGAAGATGTTTTCATTAATAGTCTGGTTTAGTATTAATTTAAC CTTGAAATAAGAAATTGGTCCTGATTTGCCACCTTCATTTTTCCATCTGCTGAAATGCCATTTCAGAATGTATAAAAGTACTTTCAGAAT TAGAAGAAAAGTGAGAGCTTCAGCAGAACGTGTCAAGTCGCTAATAACAGGAGTCGAACCTTATGTTTGAAAATTAACTGAGTGAGTTAA GTGCAAGCATAAACTAAAATTTATATGACTTTGAATTTAAGAACCACTAATAACTGTGTTCTAATTAACACAGTAATCTGTTCAGCCAAA GGATACTAACAGCCATTCTTTGGACTGTGGTTAATTTGATAACTTCAAGAAGTTATAACTTTGCTACCCTGGATTCTGATGCAATTTCAA TATAAAAAGTTGTTCCTTTCATAGTTTTTCCCCCCAAAAGAAGTGCCTATTACATTTTACCTTAATGTTTATTTATCATCCAAGTGTTCT TGATATAAAATCAGTATACAGAAAATTTTAAGAGAACTTACATTCAAGGGACATAGAGGGAAAATGTTAATGTGTATTTCATTGTTTCTT GTGGAATTTTTTTTTCATTCGGTTTGAGAATGGACAGTGTGTCTAAGGATGTGATTTAAATTTACTTAGGATGGATTTAGCATTGAGGTT ATTAAGACAAAGTTAGCAGAGGCCAGCCAGCACTGTGCTGCACAACTCCAGGAACTCCATGGTATGCTCACAATTTTCTGCAAGTTGCCT CCACTTCCAAGTGGCCAGTGATTTGTTAAAATACCTTGCCCAAGAATATAACTGATTGATGAAAGGGCATATTTAGGTCAATATAAAATA ATAGCAAGTATTTACTGAGAGCTTACTGTGTGCTAGGCATTTTCTTAATATTTCAATGTGTATTTAATCCTCACAACAACCCAATGTGGT AGGTTATTGATATCCTCTTCTTAAAAATGAGTAAATGGAGGCCCAGAGAAATGTAATTTGCCTGAGATCAAATTAAGGTTGCTTAAGATC AAACTGCTAAGAAGGGGCAGTTTGAGTCTGAGCTAGTGCTCCTAAACACTGGACATTTTTGCTGTGAACCACAGTCGGGAAGGTTTAATG >In-frame_ESYT1_ENST00000267113_chr12_56532797_+_MED14_ENST00000324817_chrX_40514312_-_6568nt AGGCAACCTCCAGCCAGTCCCTGGGTCGGGCGGATCCTCCCAGAGGTGGCACAATGGAGCGATCTCCAGGAGAGGGCCCCAGCCCCAGCC CCATGGACCAGCCCTCTGCTCCCTCCGACCCCACTGACCAGCCCCCCGCTGCTCACGCAAAGCCAGACCCAGGTTCTGGGGGCCAACCTG CTGGCCCTGGCGCGGCGGGTGAGGCCCTGGCGGTGCTGACTTCATTCGGGAGGCGGTTGCTGGTGCTGATACCTGTGTATTTGGCCGGGG CAGTGGGACTCAGCGTGGGTTTCGTGCTCTTCGGCCTCGCCCTCTACCTGGGCTGGCGCCGGGTCCGCGACGAGAAAGAACGGAGCCTTC GAGCAGCGAGGCAGCTACTGGACGACGAGGAGCAGCTCACTGCGAAAACTCTCTATATGAGTCATCGAGAGCTACCTGCCTGGGTCAGCT TCCCAGACGTGGAAAAGGCTGAATGGCTCAATAAGATTGTGGCCCAGGTCTGGCCCTTCCTGGGCCAGTATATGGAGAAGCTTCTGGCTG AAACTGTGGCTCCGGCTGTTAGGGGATCTAACCCCCATCTGCAAACATTTACATTTACACGAGTGGAACTGGGTGAAAAGCCATTGCGCA TCATTGGAGTCAAGGTTCACCCAGGTCAGAGAAAAGAGCAGATCCTGCTGGACTTGAACATCAGCTATGTAGGTGATGTGCAGATTGATG TGGAAGTGAAGAAATATTTTTGCAAAGCAGGAGTCAAGGGCATGCAGCTACATGGCGTTTTGCGGGTGATACTGGAGCCACTCATTGGGG ACCTTCCCTTCGTGGGGGCTGTGTCAATGTTCTTCATCCGACGCCCGACCCTAGACATCAACTGGACAGGGATGACCAACCTGCTGGATA TCCCAGGACTTAGCTCACTCTCTGACACCATGATCATGGACTCCATTGCTGCCTTCCTCGTGTTGCCCAACCGATTACTGGTGCCCCTTG TGCCTGACCTTCAAGATGTGGCTCAGTTGCGTTCCCCTCTGCCCAGGGGCATTATTCGAATTCACCTGCTGGCTGCTCGAGGGCTGAGTT CCAAGGACAAATATGTGAAGGGCCTGATTGAGGGCAAGTCAGACCCATATGCACTTGTGCGTTTGGGTACCCAGACATTCTGCAGTCGTG TCATTGATGAAGAACTCAACCCACAGTGGGGAGAGACTTATGAGGTGATGGTACACGAGGTCCCAGGGCAGGAGATTGAAGTGGAGGTGT TCGACAAGGATCCAGATAAAGATGACTTTCTGGGCAGAATGAAGCTGGATGTAGGGAAGGTGTTACAGGCTAGCGTTCTGGATGATTGGT TCCCTCTACAAGGTGGGCAAGGCCAAGTTCACTTGAGGCTAGAATGGCTGTCACTTTTGTCAGATGCAGAGAAACTGGAGCAGGTTCTAC AGTGGAATTGGGGAGTCTCCTCTCGACCAGATCCCCCGTCAGCTGCCATCTTAGTTGTCTACCTGGATCGGGCCCAGGATCTTCCTATGG TGACCTCTGAATTGTACCCACCACAGCTGAAGAAGGGGAACAAGGAACCCAACCCTATGGTACAACTGTCAATTCAGGATGTGACTCAGG AGAGCAAGGCTGTCTACAGTACCAACTGCCCAGTGTGGGAGGAAGCGTTCCGGTTCTTCCTACAAGACCCTCAAAGCCAGGAGCTCGATG TGCAAGTGAAGGATGATTCCAGGGCCCTGACTTTAGGAGCACTGACGCTGCCTCTGGCCCGCCTGCTGACTGCCCCAGAACTCATCCTGG ACCAGTGGTTCCAGCTCAGCAGCTCTGGTCCAAACTCCAGACTCTATATGAAACTAGTCATGAGGATCCTGTACTTGGATTCATCAGAAA TATGCTTCCCCACGGTGCCTGGTTGTCCTGGTGCTTGGGACGTGGACAGTGAGAATCCCCAGAGAGGCAGCAGTGTGGATGCCCCACCTC GACCCTGTCACACGACTCCTGATAGCCAGTTTGGGACTGAGCATGTGCTTCGGATCCATGTATTAGAGGCCCAGGACCTGATTGCCAAAG ACCGTTTCTTGGGGGGACTGGTGAAGGGCAAGTCAGACCCCTATGTCAAACTAAAGTTGGCAGGACGAAGCTTCCGGAGCCATGTTGTTC GGGAAGATCTCAATCCCCGCTGGAATGAGGTTTTTGAGGTGATCGTCACATCAGTTCCAGGCCAAGAGCTAGAGGTTGAAGTCTTTGACA AGGACTTGGACAAGGATGATTTTCTGGGCAGGTGTAAAGTGCGTCTCACCACAGTCTTAAACAGTGGCTTCCTTGATGAGTGGCTGACCC TGGAGGATGTCCCATCTGGCCGCCTGCACTTGCGCCTGGAGCGTCTCACCCCCCGTCCCACTGCTGCTGAGTTAGAGGAGGTGCTGCAGG TGAATAGTTTGATCCAGACTCAGAAGAGTGCGGAGCTGGCTGCGGCCCTGCTATCCATCTATATGGAGCGGGCAGAGGACCTCCCGCTGC GAAAAGGCACCAAGCACCTCAGCCCTTATGCTACTCTCACTGTGGGAGATAGTTCTCATAAAACCAAGACTATTTCGCAAACTTCAGCCC CTGTCTGGGATGAGAGTGCCTCCTTTCTCATCAGGAAACCACACACTGAGAGCCTAGAGTTGCAGTTCCCTGACCAAGCAACACAGCTAA AATGGAATGTTCAGTTTTGCCTGACGATCCCTCCCAGCGCGCCGCCGATTGCACCTCCTGGGACGCCTGCTGTGGTGCTGAAATCCAAAA TGCTATTTTTTCTTCAACTAACTCAGAAAACATCGGTCCCTCCCCAAGAACCTGTTAGTATTATAGTTCCAATCATTTATGACATGGCTT CAGGTACAACCCAGCAGGCAGACATTCCCAGACAGCAGAACTCTTCTGTTGCTGCTCCCATGATGGTCAGCAACATTCTGAAGAGGTTTG CAGAGATGAATCCACCACGACAAGGTGAATGCACAATATTTGCAGCTGTTCGTGATTTAATGGCTAATCTTACACTGCCCCCTGGTGGGC GTCCATAGACACTATTGTTTTTAAACCAGGAAGGCTGACAGATGAGACAACAAAAAAAATCTGAATTCAGCCTTCAGTTTAAAAAAGGAA AAGGACTTTTTTTTTAAACTTTAAGAGCTAAATATTCTAAACTGGCAAAAATTTTCAGGGTGCACTTCTTTCATCAAAATGATCATCCAT CTTTTGTATAATGAACTTGTATAGTGTGTTTAAATGGGACACATTTCAAAGGAAATAAATCAGTGTCCGTTTGCCAGTAATAAATTTAAT ATTCTGTTTTATACTATAAAGTTATGAAAATGCCAAACTTGTTTATTTAATTGTTTTCTTATGTTTTGGGTGTAATAGTCCTTTTTTGGT TTTTGTTTTGTTTTTTAAGGCAGGTCTGTCATTTTTGAATACTGTAAAACTGTGATAAACTTTATATTGAAGCTGTATTTTAATATGACC GCTTTGAATCCTTACATGAAATGTTCTGGGAGTTGTTATAAACACACCCCAAGGAAGCAATATTTAATAAAACTAGGTCAAAAACAAAAC AAAACAGTGACACTCACTTGTGTGTATATAAACTCTAGAGACATCTTAGGCCCTCCCTTCATCTTTAACCTGGTGGATGGAGCCAGTTAT TAATTTATAATAATACATGTCTGAAATTTGACCAAAAACATCTTCTTTATGTCAAGGTTAATATATTTTCTTCAGACATTCCTAACTTGA CTAGTGGTTAACATTTAGCACCTTGGTTGTCTTTCAATATATAGGATTTGGGTGAAAAATAAGGAACTTAGTCTTTGAGAAGGGACAGTA TGTGGTTCGTATTGATCAAGGATCCCAAATAATGCAATCATTCTCATCTGTTGAGGATGTGGGAACTTTTCTGTCAGGAAAATTTAGTTT ACAGAATACTTCTGCATACAACATTAATTAGGAAACAAAGAACTTTAATGCTGTACCTCTGCATGAAGTTTCTGTGAGCTTTCTTTATCT TGCTTAACTTATCCTCCTTTCCTTCCCCACCAAAATTGGGATTGTTCTAAACAATTTCAATTTAATTCATTGTCAACAAAACGATAGAAT GTTTTGCTTGGAAGAAACCTGGTCCATTCCCCTCATTGTGAAGAATCCCGAATCCTGGGCCTGTCCAGGGTCAAATGGAGTTTTTGGTAT TAATACATCTCTGCAGGGTTTCTTTTTGGAGCACTGTGCTGTCTTTCCTAGTCAGTCAGGGACTTTTTTAAGCTTCAAAGAACATGGTCT GATGCAAAGGTCTTCTACCGACTTCATGGTATTTAGGAAAAATTTTTAAGTGATAATACCATGCCGAGTTACCTGGTCACTGTAATACTG GTTCTCCATTAAAATGTAGATGCTTTGTCTAATTCCACTTCAAGATGATTTAATTGAGCTTCTATAACTATCAACTATCAAATTCTAGTT TCAAGTATCTCACTGTACCTATATCATATCTGTTCTCAACTTTGTTTGATTCTCCACTCATTTTCAATCAGAGTTGAAGCCTTCTTTGCC TTTCTTCTTTGTCTTATTTCTGCCTTCATCTCCCACTTCTCACCCAACTCTGCCACTGTTCAGGAGCAGTTGACTAAACTTTTATCCTTC CTTTAACTTAATCTTTTTATCCTTCTGTTTTTAGTTCTTACAGTGGTAATCACATCAGTTTGGCAATCTAAGATGTCTTTATCAAGGGTC AGCCCTTTTCTATTTGGAGCTGAATCTTTTCTTTCATGTAGAAATCTACATGTATATACAAGAAATGTATTTTTATCTGCAGGATAATAT TGTTTCAAATAATTTTATTAAGAGTTAACTTTTTAGGTATTTTCCCTTTTAATGTGGTTTTGAAATGTTAATTGCATTTTTACACATGAT GCATTCAGTGGACACTCTTTTTTCCTAATTATAACTCATCTCTGAATGCATTGTGCCAATCAAGAGTAAGATAGGATTCAGTGCGCAAAA TTTGCTTTTGATGCTTATTAAGAGTAAACCCATGAATTTGAATTTTTATATTATGCTTGGTACTTGGAATTGATATATACCTTATTAAAG CTTGAAAACATTTAGCATTTGAATAGTAAGTTTCATCACAAATCATGTCTTTTGCCTCTTTTGTTACCCAGGTTCGATCAAGGGGACTGG ATGCCCAAGTGATTTTCTCTAATAATCGGGTTGGGACTTAACTTTAAGGTGTTTTCAATGTGATTTTAGTATTTACAGTAATAAATAAAA TTTATACAAAGTTTCAGAGAACTACCAACTCTCTAGTTAATTTTGATGAAGATGTTTTCATTAATAGTCTGGTTTAGTATTAATTTAACC TTGAAATAAGAAATTGGTCCTGATTTGCCACCTTCATTTTTCCATCTGCTGAAATGCCATTTCAGAATGTATAAAAGTACTTTCAGAATT AGAAGAAAAGTGAGAGCTTCAGCAGAACGTGTCAAGTCGCTAATAACAGGAGTCGAACCTTATGTTTGAAAATTAACTGAGTGAGTTAAG TGCAAGCATAAACTAAAATTTATATGACTTTGAATTTAAGAACCACTAATAACTGTGTTCTAATTAACACAGTAATCTGTTCAGCCAAAG GATACTAACAGCCATTCTTTGGACTGTGGTTAATTTGATAACTTCAAGAAGTTATAACTTTGCTACCCTGGATTCTGATGCAATTTCAAT ATAAAAAGTTGTTCCTTTCATAGTTTTTCCCCCCAAAAGAAGTGCCTATTACATTTTACCTTAATGTTTATTTATCATCCAAGTGTTCTT GATATAAAATCAGTATACAGAAAATTTTAAGAGAACTTACATTCAAGGGACATAGAGGGAAAATGTTAATGTGTATTTCATTGTTTCTTG TGGAATTTTTTTTTCATTCGGTTTGAGAATGGACAGTGTGTCTAAGGATGTGATTTAAATTTACTTAGGATGGATTTAGCATTGAGGTTA TTAAGACAAAGTTAGCAGAGGCCAGCCAGCACTGTGCTGCACAACTCCAGGAACTCCATGGTATGCTCACAATTTTCTGCAAGTTGCCTC CACTTCCAAGTGGCCAGTGATTTGTTAAAATACCTTGCCCAAGAATATAACTGATTGATGAAAGGGCATATTTAGGTCAATATAAAATAA TAGCAAGTATTTACTGAGAGCTTACTGTGTGCTAGGCATTTTCTTAATATTTCAATGTGTATTTAATCCTCACAACAACCCAATGTGGTA GGTTATTGATATCCTCTTCTTAAAAATGAGTAAATGGAGGCCCAGAGAAATGTAATTTGCCTGAGATCAAATTAAGGTTGCTTAAGATCA AACTGCTAAGAAGGGGCAGTTTGAGTCTGAGCTAGTGCTCCTAAACACTGGACATTTTTGCTGTGAACCACAGTCGGGAAGGTTTAATGT >In-frame_ESYT1_ENST00000541590_chr12_56532797_+_MED14_ENST00000324817_chrX_40514312_-_6568nt AGGCAACCTCCAGCCAGTCCCTGGGTCGGGCGGATCCTCCCAGAGGTGGCACAATGGAGCGATCTCCAGGAGAGGGCCCCAGCCCCAGCC CCATGGACCAGCCCTCTGCTCCCTCCGACCCCACTGACCAGCCCCCCGCTGCTCACGCAAAGCCAGACCCAGGTTCTGGGGGCCAACCTG CTGGCCCTGGCGCGGCGGGTGAGGCCCTGGCGGTGCTGACTTCATTCGGGAGGCGGTTGCTGGTGCTGATACCTGTGTATTTGGCCGGGG CAGTGGGACTCAGCGTGGGTTTCGTGCTCTTCGGCCTCGCCCTCTACCTGGGCTGGCGCCGGGTCCGCGACGAGAAAGAACGGAGCCTTC GAGCAGCGAGGCAGCTACTGGACGACGAGGAGCAGCTCACTGCGAAAACTCTCTATATGAGTCATCGAGAGCTACCTGCCTGGGTCAGCT TCCCAGACGTGGAAAAGGCTGAATGGCTCAATAAGATTGTGGCCCAGGTCTGGCCCTTCCTGGGCCAGTATATGGAGAAGCTTCTGGCTG AAACTGTGGCTCCGGCTGTTAGGGGATCTAACCCCCATCTGCAAACATTTACATTTACACGAGTGGAACTGGGTGAAAAGCCATTGCGCA TCATTGGAGTCAAGGTTCACCCAGGTCAGAGAAAAGAGCAGATCCTGCTGGACTTGAACATCAGCTATGTAGGTGATGTGCAGATTGATG TGGAAGTGAAGAAATATTTTTGCAAAGCAGGAGTCAAGGGCATGCAGCTACATGGCGTTTTGCGGGTGATACTGGAGCCACTCATTGGGG ACCTTCCCTTCGTGGGGGCTGTGTCAATGTTCTTCATCCGACGCCCGACCCTAGACATCAACTGGACAGGGATGACCAACCTGCTGGATA TCCCAGGACTTAGCTCACTCTCTGACACCATGATCATGGACTCCATTGCTGCCTTCCTCGTGTTGCCCAACCGATTACTGGTGCCCCTTG TGCCTGACCTTCAAGATGTGGCTCAGTTGCGTTCCCCTCTGCCCAGGGGCATTATTCGAATTCACCTGCTGGCTGCTCGAGGGCTGAGTT CCAAGGACAAATATGTGAAGGGCCTGATTGAGGGCAAGTCAGACCCATATGCACTTGTGCGTTTGGGTACCCAGACATTCTGCAGTCGTG TCATTGATGAAGAACTCAACCCACAGTGGGGAGAGACTTATGAGGTGATGGTACACGAGGTCCCAGGGCAGGAGATTGAAGTGGAGGTGT TCGACAAGGATCCAGATAAAGATGACTTTCTGGGCAGAATGAAGCTGGATGTAGGGAAGGTGTTACAGGCTAGCGTTCTGGATGATTGGT TCCCTCTACAAGGTGGGCAAGGCCAAGTTCACTTGAGGCTAGAATGGCTGTCACTTTTGTCAGATGCAGAGAAACTGGAGCAGGTTCTAC AGTGGAATTGGGGAGTCTCCTCTCGACCAGATCCCCCGTCAGCTGCCATCTTAGTTGTCTACCTGGATCGGGCCCAGGATCTTCCTATGG TGACCTCTGAATTGTACCCACCACAGCTGAAGAAGGGGAACAAGGAACCCAACCCTATGGTACAACTGTCAATTCAGGATGTGACTCAGG AGAGCAAGGCTGTCTACAGTACCAACTGCCCAGTGTGGGAGGAAGCGTTCCGGTTCTTCCTACAAGACCCTCAAAGCCAGGAGCTCGATG TGCAAGTGAAGGATGATTCCAGGGCCCTGACTTTAGGAGCACTGACGCTGCCTCTGGCCCGCCTGCTGACTGCCCCAGAACTCATCCTGG ACCAGTGGTTCCAGCTCAGCAGCTCTGGTCCAAACTCCAGACTCTATATGAAACTAGTCATGAGGATCCTGTACTTGGATTCATCAGAAA TATGCTTCCCCACGGTGCCTGGTTGTCCTGGTGCTTGGGACGTGGACAGTGAGAATCCCCAGAGAGGCAGCAGTGTGGATGCCCCACCTC GACCCTGTCACACGACTCCTGATAGCCAGTTTGGGACTGAGCATGTGCTTCGGATCCATGTATTAGAGGCCCAGGACCTGATTGCCAAAG ACCGTTTCTTGGGGGGACTGGTGAAGGGCAAGTCAGACCCCTATGTCAAACTAAAGTTGGCAGGACGAAGCTTCCGGAGCCATGTTGTTC GGGAAGATCTCAATCCCCGCTGGAATGAGGTTTTTGAGGTGATCGTCACATCAGTTCCAGGCCAAGAGCTAGAGGTTGAAGTCTTTGACA AGGACTTGGACAAGGATGATTTTCTGGGCAGGTGTAAAGTGCGTCTCACCACAGTCTTAAACAGTGGCTTCCTTGATGAGTGGCTGACCC TGGAGGATGTCCCATCTGGCCGCCTGCACTTGCGCCTGGAGCGTCTCACCCCCCGTCCCACTGCTGCTGAGTTAGAGGAGGTGCTGCAGG TGAATAGTTTGATCCAGACTCAGAAGAGTGCGGAGCTGGCTGCGGCCCTGCTATCCATCTATATGGAGCGGGCAGAGGACCTCCCGCTGC GAAAAGGCACCAAGCACCTCAGCCCTTATGCTACTCTCACTGTGGGAGATAGTTCTCATAAAACCAAGACTATTTCGCAAACTTCAGCCC CTGTCTGGGATGAGAGTGCCTCCTTTCTCATCAGGAAACCACACACTGAGAGCCTAGAGTTGCAGTTCCCTGACCAAGCAACACAGCTAA AATGGAATGTTCAGTTTTGCCTGACGATCCCTCCCAGCGCGCCGCCGATTGCACCTCCTGGGACGCCTGCTGTGGTGCTGAAATCCAAAA TGCTATTTTTTCTTCAACTAACTCAGAAAACATCGGTCCCTCCCCAAGAACCTGTTAGTATTATAGTTCCAATCATTTATGACATGGCTT CAGGTACAACCCAGCAGGCAGACATTCCCAGACAGCAGAACTCTTCTGTTGCTGCTCCCATGATGGTCAGCAACATTCTGAAGAGGTTTG CAGAGATGAATCCACCACGACAAGGTGAATGCACAATATTTGCAGCTGTTCGTGATTTAATGGCTAATCTTACACTGCCCCCTGGTGGGC GTCCATAGACACTATTGTTTTTAAACCAGGAAGGCTGACAGATGAGACAACAAAAAAAATCTGAATTCAGCCTTCAGTTTAAAAAAGGAA AAGGACTTTTTTTTTAAACTTTAAGAGCTAAATATTCTAAACTGGCAAAAATTTTCAGGGTGCACTTCTTTCATCAAAATGATCATCCAT CTTTTGTATAATGAACTTGTATAGTGTGTTTAAATGGGACACATTTCAAAGGAAATAAATCAGTGTCCGTTTGCCAGTAATAAATTTAAT ATTCTGTTTTATACTATAAAGTTATGAAAATGCCAAACTTGTTTATTTAATTGTTTTCTTATGTTTTGGGTGTAATAGTCCTTTTTTGGT TTTTGTTTTGTTTTTTAAGGCAGGTCTGTCATTTTTGAATACTGTAAAACTGTGATAAACTTTATATTGAAGCTGTATTTTAATATGACC GCTTTGAATCCTTACATGAAATGTTCTGGGAGTTGTTATAAACACACCCCAAGGAAGCAATATTTAATAAAACTAGGTCAAAAACAAAAC AAAACAGTGACACTCACTTGTGTGTATATAAACTCTAGAGACATCTTAGGCCCTCCCTTCATCTTTAACCTGGTGGATGGAGCCAGTTAT TAATTTATAATAATACATGTCTGAAATTTGACCAAAAACATCTTCTTTATGTCAAGGTTAATATATTTTCTTCAGACATTCCTAACTTGA CTAGTGGTTAACATTTAGCACCTTGGTTGTCTTTCAATATATAGGATTTGGGTGAAAAATAAGGAACTTAGTCTTTGAGAAGGGACAGTA TGTGGTTCGTATTGATCAAGGATCCCAAATAATGCAATCATTCTCATCTGTTGAGGATGTGGGAACTTTTCTGTCAGGAAAATTTAGTTT ACAGAATACTTCTGCATACAACATTAATTAGGAAACAAAGAACTTTAATGCTGTACCTCTGCATGAAGTTTCTGTGAGCTTTCTTTATCT TGCTTAACTTATCCTCCTTTCCTTCCCCACCAAAATTGGGATTGTTCTAAACAATTTCAATTTAATTCATTGTCAACAAAACGATAGAAT GTTTTGCTTGGAAGAAACCTGGTCCATTCCCCTCATTGTGAAGAATCCCGAATCCTGGGCCTGTCCAGGGTCAAATGGAGTTTTTGGTAT TAATACATCTCTGCAGGGTTTCTTTTTGGAGCACTGTGCTGTCTTTCCTAGTCAGTCAGGGACTTTTTTAAGCTTCAAAGAACATGGTCT GATGCAAAGGTCTTCTACCGACTTCATGGTATTTAGGAAAAATTTTTAAGTGATAATACCATGCCGAGTTACCTGGTCACTGTAATACTG GTTCTCCATTAAAATGTAGATGCTTTGTCTAATTCCACTTCAAGATGATTTAATTGAGCTTCTATAACTATCAACTATCAAATTCTAGTT TCAAGTATCTCACTGTACCTATATCATATCTGTTCTCAACTTTGTTTGATTCTCCACTCATTTTCAATCAGAGTTGAAGCCTTCTTTGCC TTTCTTCTTTGTCTTATTTCTGCCTTCATCTCCCACTTCTCACCCAACTCTGCCACTGTTCAGGAGCAGTTGACTAAACTTTTATCCTTC CTTTAACTTAATCTTTTTATCCTTCTGTTTTTAGTTCTTACAGTGGTAATCACATCAGTTTGGCAATCTAAGATGTCTTTATCAAGGGTC AGCCCTTTTCTATTTGGAGCTGAATCTTTTCTTTCATGTAGAAATCTACATGTATATACAAGAAATGTATTTTTATCTGCAGGATAATAT TGTTTCAAATAATTTTATTAAGAGTTAACTTTTTAGGTATTTTCCCTTTTAATGTGGTTTTGAAATGTTAATTGCATTTTTACACATGAT GCATTCAGTGGACACTCTTTTTTCCTAATTATAACTCATCTCTGAATGCATTGTGCCAATCAAGAGTAAGATAGGATTCAGTGCGCAAAA TTTGCTTTTGATGCTTATTAAGAGTAAACCCATGAATTTGAATTTTTATATTATGCTTGGTACTTGGAATTGATATATACCTTATTAAAG CTTGAAAACATTTAGCATTTGAATAGTAAGTTTCATCACAAATCATGTCTTTTGCCTCTTTTGTTACCCAGGTTCGATCAAGGGGACTGG ATGCCCAAGTGATTTTCTCTAATAATCGGGTTGGGACTTAACTTTAAGGTGTTTTCAATGTGATTTTAGTATTTACAGTAATAAATAAAA TTTATACAAAGTTTCAGAGAACTACCAACTCTCTAGTTAATTTTGATGAAGATGTTTTCATTAATAGTCTGGTTTAGTATTAATTTAACC TTGAAATAAGAAATTGGTCCTGATTTGCCACCTTCATTTTTCCATCTGCTGAAATGCCATTTCAGAATGTATAAAAGTACTTTCAGAATT AGAAGAAAAGTGAGAGCTTCAGCAGAACGTGTCAAGTCGCTAATAACAGGAGTCGAACCTTATGTTTGAAAATTAACTGAGTGAGTTAAG TGCAAGCATAAACTAAAATTTATATGACTTTGAATTTAAGAACCACTAATAACTGTGTTCTAATTAACACAGTAATCTGTTCAGCCAAAG GATACTAACAGCCATTCTTTGGACTGTGGTTAATTTGATAACTTCAAGAAGTTATAACTTTGCTACCCTGGATTCTGATGCAATTTCAAT ATAAAAAGTTGTTCCTTTCATAGTTTTTCCCCCCAAAAGAAGTGCCTATTACATTTTACCTTAATGTTTATTTATCATCCAAGTGTTCTT GATATAAAATCAGTATACAGAAAATTTTAAGAGAACTTACATTCAAGGGACATAGAGGGAAAATGTTAATGTGTATTTCATTGTTTCTTG TGGAATTTTTTTTTCATTCGGTTTGAGAATGGACAGTGTGTCTAAGGATGTGATTTAAATTTACTTAGGATGGATTTAGCATTGAGGTTA TTAAGACAAAGTTAGCAGAGGCCAGCCAGCACTGTGCTGCACAACTCCAGGAACTCCATGGTATGCTCACAATTTTCTGCAAGTTGCCTC CACTTCCAAGTGGCCAGTGATTTGTTAAAATACCTTGCCCAAGAATATAACTGATTGATGAAAGGGCATATTTAGGTCAATATAAAATAA TAGCAAGTATTTACTGAGAGCTTACTGTGTGCTAGGCATTTTCTTAATATTTCAATGTGTATTTAATCCTCACAACAACCCAATGTGGTA GGTTATTGATATCCTCTTCTTAAAAATGAGTAAATGGAGGCCCAGAGAAATGTAATTTGCCTGAGATCAAATTAAGGTTGCTTAAGATCA AACTGCTAAGAAGGGGCAGTTTGAGTCTGAGCTAGTGCTCCTAAACACTGGACATTTTTGCTGTGAACCACAGTCGGGAAGGTTTAATGT |
Top |
FusionGenePPI for ESYT1_MED14 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ESYT1 | CDK2, MYH10, SFXN3, VCAM1, FN1, ITGA4, CFTR, RPA3, RPA2, RPA1, MDM2, DERL1, DERL2, SYNJ2BP, ESYT2, ARL6IP5, YIF1B, FAF2, EDEM1, SCGN, BTN2A1, TREML2, NTRK1, NUP35, TCTN2, TCTN3, EVC2, TMEM17, TMEM216, ATL3, FOXL1, RHOU, U2AF2, CDH1, TSPAN11, UGT1A9, KCNC4, HCCS, COMT, RDH11, DCAKD, TMX1, GBA, NCDN | MED14 | MED10, MED9, MED29, MED19, MED28, MED26, PPARGC1A, NR3C1, CDK8, MED21, MED6, VDR, HNF4A, STAT2, ESR1, ESR2, MED1, BRD4, GATA1, PARP1, TRRAP, SREBF1, MED12, MED18, ZC3H13, OBFC1, QKI, TADA2A, MED25, MED15, TRA, MED23, MED7, MED24, CRSP5, MED17, MED27, ACTN1, ACTN2, DCTN1, UACA, NECAB2, CTDP1, MED16, MED4, MED13, MED8, MED11, PPP6R1, FBXW7, EPAS1, PPARG, CDK19, HECW2, CCNC, NR1I3, TCL1B, HIF1A, UNK, NTRK1, ACTL6B, MED20, KIF11, LAMB3, POLR2G, SUPT5H, EMC2, BIRC5, LMO2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | MED14 | chr12:56532797 | chrX:40514312 | ENST00000324817 | - | 27 | 31 | 500_824 | 1324 | 1455 | SREBF1 |
| Tgene | MED14 | chr12:56532797 | chrX:40514312 | ENST00000324817 | - | 27 | 31 | 188_566 | 1324 | 1455 | STAT2 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for ESYT1_MED14 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ESYT1_MED14 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | MED14 | C0014175 | Endometriosis | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|