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Fusion gene ID: 11961 |
FusionGeneSummary for ERC1_TACC3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ERC1_TACC3 | Fusion gene ID: 11961 | Hgene | Tgene | Gene symbol | ERC1 | TACC3 | Gene ID | 23085 | 10460 |
| Gene name | ELKS/RAB6-interacting/CAST family member 1 | transforming acidic coiled-coil containing protein 3 | |
| Synonyms | Cast2|ELKS|ERC-1|RAB6IP2 | ERIC-1|ERIC1 | |
| Cytomap | 12p13.33 | 4p16.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ELKS/Rab6-interacting/CAST family member 1RAB6 interacting protein 2 | transforming acidic coiled-coil-containing protein 3 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q8IUD2 | Q9Y6A5 | |
| Ensembl transtripts involved in fusion gene | ENST00000543086, ENST00000546231, ENST00000397203, ENST00000360905, ENST00000589028, ENST00000355446, ENST00000536573, | ENST00000313288, | |
| Fusion gene scores | * DoF score | 20 X 16 X 12=3840 | 6 X 10 X 13=780 |
| # samples | 23 | 42 | |
| ** MAII score | log2(23/3840*10)=-4.06140054466414 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(42/780*10)=-0.893084796083488 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ERC1 [Title/Abstract] AND TACC3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ERC1 | GO:0007252 | I-kappaB phosphorylation | 15218148 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-E2-A9RU-01A | ERC1 | chr12 | 1192746 | + | TACC3 | chr4 | 1741429 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000543086 | ENST00000313288 | ERC1 | chr12 | 1192746 | + | TACC3 | chr4 | 1741429 | + |
| In-frame | ENST00000546231 | ENST00000313288 | ERC1 | chr12 | 1192746 | + | TACC3 | chr4 | 1741429 | + |
| In-frame | ENST00000397203 | ENST00000313288 | ERC1 | chr12 | 1192746 | + | TACC3 | chr4 | 1741429 | + |
| In-frame | ENST00000360905 | ENST00000313288 | ERC1 | chr12 | 1192746 | + | TACC3 | chr4 | 1741429 | + |
| In-frame | ENST00000589028 | ENST00000313288 | ERC1 | chr12 | 1192746 | + | TACC3 | chr4 | 1741429 | + |
| In-frame | ENST00000355446 | ENST00000313288 | ERC1 | chr12 | 1192746 | + | TACC3 | chr4 | 1741429 | + |
| 3UTR-3CDS | ENST00000536573 | ENST00000313288 | ERC1 | chr12 | 1192746 | + | TACC3 | chr4 | 1741429 | + |
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FusionProtFeatures for ERC1_TACC3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ERC1 | TACC3 |
| Plays a role in the microtubule-dependent coupling ofthe nucleus and the centrosome. Involved in the processes thatregulate centrosome-mediated interkinetic nuclear migration (INM)of neural progenitors (By similarity). Acts as component of theTACC3/ch-TOG/clathrin complex proposed to contribute tostabilization of kinetochore fibers of the mitotic spindle byacting as inter-microtubule bridge. The TACC3/ch-TOG/clathrincomplex is required for the maintenance of kinetochore fibertension (PubMed:21297582, PubMed:23532825). May be involved in thecontrol of cell growth and differentiation. May contribute tocancer (PubMed:14767476). {ECO:0000250|UniProtKB:Q9JJ11,ECO:0000269|PubMed:14767476, ECO:0000269|PubMed:21297582,ECO:0000269|PubMed:23532825}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000360905 | + | 3 | 19 | 1060_1100 | 362 | 1117 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000360905 | + | 3 | 19 | 144_988 | 362 | 1117 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000397203 | + | 3 | 19 | 1060_1100 | 362 | 1117 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000397203 | + | 3 | 19 | 144_988 | 362 | 1117 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000543086 | + | 3 | 18 | 1060_1100 | 362 | 1089 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000543086 | + | 3 | 18 | 144_988 | 362 | 1089 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000589028 | + | 2 | 18 | 1060_1100 | 362 | 1117 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000589028 | + | 2 | 18 | 144_988 | 362 | 1117 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000360905 | + | 3 | 19 | 1046_1108 | 362 | 1117 | Domain | FIP-RBD |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000397203 | + | 3 | 19 | 1046_1108 | 362 | 1117 | Domain | FIP-RBD |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000543086 | + | 3 | 18 | 1046_1108 | 362 | 1089 | Domain | FIP-RBD |
| Hgene | >ERC1 | chr12:1192746 | chr4:1741429 | ENST00000589028 | + | 2 | 18 | 1046_1108 | 362 | 1117 | Domain | FIP-RBD |
| Tgene | TACC3 | chr12:1192746 | chr4:1741429 | ENST00000313288 | + | 9 | 16 | 637_837 | 647 | 839 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | TACC3 | chr12:1192746 | chr4:1741429 | ENST00000313288 | + | 9 | 16 | 155_160 | 647 | 839 | Compositional bias | Note=Poly-Ser |
| Tgene | TACC3 | chr12:1192746 | chr4:1741429 | ENST00000313288 | + | 9 | 16 | 522_577 | 647 | 839 | Region | Necessary but not sufficient for spindle localization |
| Tgene | TACC3 | chr12:1192746 | chr4:1741429 | ENST00000313288 | + | 9 | 16 | 594_838 | 647 | 839 | Region | Necessary but not sufficient for spindle localization |
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FusionGeneSequence for ERC1_TACC3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ERC1_ENST00000543086_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_554aa MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML REVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEV IEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELT >In-frame_ERC1_ENST00000546231_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_554aa MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML REVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEV IEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELT >In-frame_ERC1_ENST00000397203_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_554aa MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML REVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEV IEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELT >In-frame_ERC1_ENST00000360905_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_554aa MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML REVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEV IEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELT >In-frame_ERC1_ENST00000589028_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_554aa MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML REVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEV IEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELT >In-frame_ERC1_ENST00000355446_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_554aa MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMT LGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRL HAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML REVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEV IEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ERC1_ENST00000543086_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_1662nt ATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTG GGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAA TCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACA CTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGT GACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACA ATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGT TCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATT TGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGG GACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTT CATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAG ACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCAT GAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTG AGAGAGGTAAAGGCGACACAGGAGGAGAACCGGGAGCTGAGGAGCAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGATC ATGGACAGGTTCGAAGAGGTTGTGTACCAGGCCATGGAGGAAGTTCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCTA AAAGAAAAAGACCAACTTACCACAGATCTGAACTCCATGGAGAAGTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGTG ATCGAGGGCTACCGCAAGAACGAAGAGTCACTGAAGAAGTGCGTGGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCAA GCCCTGAAGGCCCACGCGGAGGAGAAGCTGCAGCTGGCAAACGAGGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGCC CTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCTGGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACC >In-frame_ERC1_ENST00000546231_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_1662nt ATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTG GGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAA TCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACA CTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGT GACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACA ATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGT TCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATT TGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGG GACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTT CATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAG ACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCAT GAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTG AGAGAGGTAAAGGCGACACAGGAGGAGAACCGGGAGCTGAGGAGCAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGATC ATGGACAGGTTCGAAGAGGTTGTGTACCAGGCCATGGAGGAAGTTCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCTA AAAGAAAAAGACCAACTTACCACAGATCTGAACTCCATGGAGAAGTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGTG ATCGAGGGCTACCGCAAGAACGAAGAGTCACTGAAGAAGTGCGTGGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCAA GCCCTGAAGGCCCACGCGGAGGAGAAGCTGCAGCTGGCAAACGAGGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGCC CTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCTGGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACC >In-frame_ERC1_ENST00000397203_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_1662nt ATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTG GGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAA TCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACA CTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGT GACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACA ATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGT TCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATT TGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGG GACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTT CATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAG ACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCAT GAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTG AGAGAGGTAAAGGCGACACAGGAGGAGAACCGGGAGCTGAGGAGCAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGATC ATGGACAGGTTCGAAGAGGTTGTGTACCAGGCCATGGAGGAAGTTCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCTA AAAGAAAAAGACCAACTTACCACAGATCTGAACTCCATGGAGAAGTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGTG ATCGAGGGCTACCGCAAGAACGAAGAGTCACTGAAGAAGTGCGTGGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCAA GCCCTGAAGGCCCACGCGGAGGAGAAGCTGCAGCTGGCAAACGAGGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGCC CTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCTGGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACC >In-frame_ERC1_ENST00000360905_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_1662nt ATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTG GGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAA TCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACA CTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGT GACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACA ATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGT TCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATT TGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGG GACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTT CATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAG ACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCAT GAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTG AGAGAGGTAAAGGCGACACAGGAGGAGAACCGGGAGCTGAGGAGCAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGATC ATGGACAGGTTCGAAGAGGTTGTGTACCAGGCCATGGAGGAAGTTCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCTA AAAGAAAAAGACCAACTTACCACAGATCTGAACTCCATGGAGAAGTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGTG ATCGAGGGCTACCGCAAGAACGAAGAGTCACTGAAGAAGTGCGTGGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCAA GCCCTGAAGGCCCACGCGGAGGAGAAGCTGCAGCTGGCAAACGAGGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGCC CTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCTGGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACC >In-frame_ERC1_ENST00000589028_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_1662nt ATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTG GGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAA TCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACA CTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGT GACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACA ATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGT TCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATT TGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGG GACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTT CATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAG ACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCAT GAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTG AGAGAGGTAAAGGCGACACAGGAGGAGAACCGGGAGCTGAGGAGCAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGATC ATGGACAGGTTCGAAGAGGTTGTGTACCAGGCCATGGAGGAAGTTCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCTA AAAGAAAAAGACCAACTTACCACAGATCTGAACTCCATGGAGAAGTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGTG ATCGAGGGCTACCGCAAGAACGAAGAGTCACTGAAGAAGTGCGTGGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCAA GCCCTGAAGGCCCACGCGGAGGAGAAGCTGCAGCTGGCAAACGAGGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGCC CTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCTGGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACC >In-frame_ERC1_ENST00000355446_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_1662nt ATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTG GGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAA TCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACA CTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGT GACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACA ATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGT TCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATT TGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGG GACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTT CATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAG ACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCAT GAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTG AGAGAGGTAAAGGCGACACAGGAGGAGAACCGGGAGCTGAGGAGCAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGATC ATGGACAGGTTCGAAGAGGTTGTGTACCAGGCCATGGAGGAAGTTCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCTA AAAGAAAAAGACCAACTTACCACAGATCTGAACTCCATGGAGAAGTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGTG ATCGAGGGCTACCGCAAGAACGAAGAGTCACTGAAGAAGTGCGTGGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCAA GCCCTGAAGGCCCACGCGGAGGAGAAGCTGCAGCTGGCAAACGAGGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGCC CTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCTGGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ERC1_ENST00000543086_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_2091nt GGGCGCGGTGACGTCGCGGGCGCCTGGGCCGTGCTGTGGCGGCGGCGGCGGCGGTAGTGGCGGCGGCGGCGGTGCCTGGGCGGCAGCAGC AGCAGTAGCGGCAGCCCTGAGGACGATATGGTGTAAGATACTTCTTCAAGATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACC AACTTGTAGCCATAGAGACACCTCACAAGGTTCCCATTTTTGTTGTTGTTGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAAC CATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTT GGGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACA ATCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGAC ACTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAG TGACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACAC AATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAG TTCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCAT TTGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAG GGACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCT TCATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCA GACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCA TGAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTT GAGAGAGGTAAAGGCGACACAGGAGGAGAACCGGGAGCTGAGGAGCAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGAT CATGGACAGGTTCGAAGAGGTTGTGTACCAGGCCATGGAGGAAGTTCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCT AAAAGAAAAAGACCAACTTACCACAGATCTGAACTCCATGGAGAAGTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGT GATCGAGGGCTACCGCAAGAACGAAGAGTCACTGAAGAAGTGCGTGGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCA AGCCCTGAAGGCCCACGCGGAGGAGAAGCTGCAGCTGGCAAACGAGGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGC CCTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCTGGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGAC CAGGATCTGCGACGACCTCATCTCCAAGATGGAGAAGATCTGACCTCCACGGAGCCGCTGTCCCCGCCCCCCTGCTCCCGTCTGTCTGTC CTGTCTGATTCTCTTAGGTGTCATGTTCTTTTTTCTGTCTTGTCTTCAACTTTTTTAAAAACTAGATTGCTTTGAAAACATGACTCAATA >In-frame_ERC1_ENST00000546231_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_2348nt GGGCCGTGCTGTGGCGGCGGCGGCGGCGGTAGTGGCGGCGGCGGCGGTGCCTGGGCGGCAGCAGCAGCAGTAGCGGCAGCCCTGAGGACG GTGAGACGGCCGCGGCGGCGGCGACAGCGCGGAAGTCGCGCGGGACCCAGAGCTTCCCCCCTGTCGCTAGTGCTGAGGCTTTCGCCTTTC CTACCCAGCTTCTTGCTCACGGCCCGGGCTGGGCTGGGCAGGGCAACGCGCCCCCGGGGAGGGGCGGAGCTGTAGGTTGGTCTTGAACTC CTGGCCTCAAGCGATCTTCCTACCTTGGCCTCCCAGAGCGCTGGGATTATAGGCATGAGCCATTGCACTTGGCACTTTTTTTGTTTGTTT TCCAGTTGCATGATATGGTGTAAGATACTTCTTCAAGATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACCAACTTGTAGCCAT AGAGACACCTCACAAGGTTCCCATTTTTGTTGTTGTTGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAACCATGTATGGAAGT GCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTGGGTCACCGTCGA ACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAATCTTTAAATGCT GCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACACTTGGCCGTTCT GGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGTGACACCATAGCA TTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACAATCATGGATCTG CAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGTTCTTCAATGAAT AGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATTTGGAAGGAACAG TACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGGGACCTGAATCAG CTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTTCATGCTGAGCAT GAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAGACCCTAAATGCT CGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCATGAGAGAACAAGA CGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTGAGAGAGGTAAAG GCGACACAGGAGGAGAACCGGGAGCTGAGGAGCAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGATCATGGACAGGTTC GAAGAGGTTGTGTACCAGGCCATGGAGGAAGTTCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCTAAAAGAAAAAGAC CAACTTACCACAGATCTGAACTCCATGGAGAAGTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGTGATCGAGGGCTAC CGCAAGAACGAAGAGTCACTGAAGAAGTGCGTGGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCAAGCCCTGAAGGCC CACGCGGAGGAGAAGCTGCAGCTGGCAAACGAGGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGCCCTCCAGGCCAGC CTGAGGAAGGAGCAGATGCGCATCCAGTCGCTGGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACCAGGATCTGCGAC GACCTCATCTCCAAGATGGAGAAGATCTGACCTCCACGGAGCCGCTGTCCCCGCCCCCCTGCTCCCGTCTGTCTGTCCTGTCTGATTCTC TTAGGTGTCATGTTCTTTTTTCTGTCTTGTCTTCAACTTTTTTAAAAACTAGATTGCTTTGAAAACATGACTCAATAAAAGTTTCCTTTC >In-frame_ERC1_ENST00000397203_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_2226nt GTGCTGTGGCGGCGGCGGCGGCGGTAGTGGCGGCGGCGGCGGTGCCTGGGCGGCAGCAGCAGCAGTAGCGGCAGCCCTGAGGACGGTGAG ACGGCCGCGGCGGCGGCGACAGCGCGGAAGTCGCGCGGGACCCAGAGCTTCCCCCCTGTCGCTAGTGCTGAGGCTTTCGCCTTTCCTACC CAGCTTCTTGCTCACGGCCCGGGCTGGGCTGGGCAGGGCAACGCGCCCCCGGGGAGGGGCGGAGCTGTAGATATGGTGTAAGATACTTCT TCAAGATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACCAACTTGTAGCCATAGAGACACCTCACAAGGTTCCCATTTTTGTTG TTGTTGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAACCATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAG CCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTGGGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAG TGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAATCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAG TGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACACTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGAC TGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGTGACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTAT GGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACAATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAA TGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGTTCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAA GAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATTTGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACAT GCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGGGACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGG CGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTTCATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCG AAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAGACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAAT GTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCATGAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCA CCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTGAGAGAGGTAAAGGCGACACAGGAGGAGAACCGGGAGCTGAGGAG CAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGATCATGGACAGGTTCGAAGAGGTTGTGTACCAGGCCATGGAGGAAGT TCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCTAAAAGAAAAAGACCAACTTACCACAGATCTGAACTCCATGGAGAA GTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGTGATCGAGGGCTACCGCAAGAACGAAGAGTCACTGAAGAAGTGCGT GGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCAAGCCCTGAAGGCCCACGCGGAGGAGAAGCTGCAGCTGGCAAACGA GGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGCCCTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCT GGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACCAGGATCTGCGACGACCTCATCTCCAAGATGGAGAAGATCTGACC TCCACGGAGCCGCTGTCCCCGCCCCCCTGCTCCCGTCTGTCTGTCCTGTCTGATTCTCTTAGGTGTCATGTTCTTTTTTCTGTCTTGTCT >In-frame_ERC1_ENST00000360905_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_2001nt AGCAGTAGCGGCAGCCCTGAGGACGATATGGTGTAAGATACTTCTTCAAGATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACC AACTTGTAGCCATAGAGACACCTCACAAGGTTCCCATTTTTGTTGTTGTTGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAAC CATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTT GGGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACA ATCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGAC ACTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAG TGACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACAC AATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAG TTCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCAT TTGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAG GGACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCT TCATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCA GACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCA TGAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTT GAGAGAGGTAAAGGCGACACAGGAGGAGAACCGGGAGCTGAGGAGCAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGAT CATGGACAGGTTCGAAGAGGTTGTGTACCAGGCCATGGAGGAAGTTCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCT AAAAGAAAAAGACCAACTTACCACAGATCTGAACTCCATGGAGAAGTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGT GATCGAGGGCTACCGCAAGAACGAAGAGTCACTGAAGAAGTGCGTGGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCA AGCCCTGAAGGCCCACGCGGAGGAGAAGCTGCAGCTGGCAAACGAGGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGC CCTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCTGGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGAC CAGGATCTGCGACGACCTCATCTCCAAGATGGAGAAGATCTGACCTCCACGGAGCCGCTGTCCCCGCCCCCCTGCTCCCGTCTGTCTGTC CTGTCTGATTCTCTTAGGTGTCATGTTCTTTTTTCTGTCTTGTCTTCAACTTTTTTAAAAACTAGATTGCTTTGAAAACATGACTCAATA >In-frame_ERC1_ENST00000589028_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_1977nt GATATGGTGTAAGATACTTCTTCAAGATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACCAACTTGTAGCCATAGAGACACCTC ACAAGGTTCCCATTTTTGTTGTTGTTGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAACCATGTATGGAAGTGCCCGCTCTGT TGGGAAGGTGGAGCCGAGCAGCCAGAGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTGGGTCACCGTCGAACCAACAGTAC GGGAGGGAGTTCGGGAAGCAGTGTTGGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAATCTTTAAATGCTGCCTATGCCAC CTCTGGCCCTATGTATCTAAGTGACCATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACACTTGGCCGTTCTGGGGGACGTCT GCCTTACGGTGTTCGGATGACTGCTATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGTGACACCATAGCATTTGGAGAGCA TCACCTCCCTCCTGTGAGTATGGCATCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACAATCATGGATCTGCAGACACAGCT GAAGGAAGTATTAAGAGAAAATGATCTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGTTCTTCAATGAATAGCATCAAGAC CTTCTGGAGCCCAGAGCTGAAGAAGGAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATTTGGAAGGAACAGTACAGAGTTGT ACAGGAGGAAAACCAGCACATGCAGATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGGGACCTGAATCAGCTGTTTCAGCA GGATAGTAGCAGCAGGACTGGCGAACCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTTCATGCTGAGCATGAGCGGCAGGC CAAAGAGCTGTTTCTTCTTCGAAAGACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAGACCCTAAATGCTCGGGATGAATC CATTAAGAAGCTTCTGGAAATGTTGCAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCATGAGAGAACAAGACGACTGGCAGA GGCAGAGATGCACGTTCATCACCTAGAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTGAGAGAGGTAAAGGCGACACAGGA GGAGAACCGGGAGCTGAGGAGCAGGTGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGATCATGGACAGGTTCGAAGAGGTTGT GTACCAGGCCATGGAGGAAGTTCAGAAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCTAAAAGAAAAAGACCAACTTACCAC AGATCTGAACTCCATGGAGAAGTCCTTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGTGATCGAGGGCTACCGCAAGAACGA AGAGTCACTGAAGAAGTGCGTGGAGGATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCAAGCCCTGAAGGCCCACGCGGAGGA GAAGCTGCAGCTGGCAAACGAGGAGATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGCCCTCCAGGCCAGCCTGAGGAAGGA GCAGATGCGCATCCAGTCGCTGGAGAAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACCAGGATCTGCGACGACCTCATCTC CAAGATGGAGAAGATCTGACCTCCACGGAGCCGCTGTCCCCGCCCCCCTGCTCCCGTCTGTCTGTCCTGTCTGATTCTCTTAGGTGTCAT >In-frame_ERC1_ENST00000355446_chr12_1192746_+_TACC3_ENST00000313288_chr4_1741429_+_1952nt GATTGGACAGCTGGGGACCTTCTTCTGATTAACCTTAAACCAACTTGTAGCCATAGAGACACCTCACAAGGTTCCCATTTTTGTTGTTGT TGTTGTTGATTTTCTGCTCACACCTTTCCTGACCTTGCAACCATGTATGGAAGTGCCCGCTCTGTTGGGAAGGTGGAGCCGAGCAGCCAG AGCCCTGGGCGTTCACCCAGGCTTCCACGTTCCCCTCGCTTGGGTCACCGTCGAACCAACAGTACGGGAGGGAGTTCGGGAAGCAGTGTT GGAGGTGGCAGTGGGAAAACCCTTTCAATGGAAAATATACAATCTTTAAATGCTGCCTATGCCACCTCTGGCCCTATGTATCTAAGTGAC CATGAAAATGTGGGTTCAGAAACACCTAAAAGCACCATGACACTTGGCCGTTCTGGGGGACGTCTGCCTTACGGTGTTCGGATGACTGCT ATGGGTAGTAGCCCCAATATAGCTAGCAGTGGGGTTGCTAGTGACACCATAGCATTTGGAGAGCATCACCTCCCTCCTGTGAGTATGGCA TCCACTGTACCTCACTCCCTTCGTCAGGCGAGAGATAACACAATCATGGATCTGCAGACACAGCTGAAGGAAGTATTAAGAGAAAATGAT CTCTTGCGGAAGGATGTGGAAGTAAAGGAGAGCAAATTGAGTTCTTCAATGAATAGCATCAAGACCTTCTGGAGCCCAGAGCTGAAGAAG GAACGAGCCCTGAGAAAAGATGAAGCTTCCAAAATCACCATTTGGAAGGAACAGTACAGAGTTGTACAGGAGGAAAACCAGCACATGCAG ATGACAATCCAGGCTCTCCAGGATGAATTGCGGATCCAGAGGGACCTGAATCAGCTGTTTCAGCAGGATAGTAGCAGCAGGACTGGCGAA CCTTGTGTAGCAGAGCTGACAGAGGAGAACTTTCAGAGGCTTCATGCTGAGCATGAGCGGCAGGCCAAAGAGCTGTTTCTTCTTCGAAAG ACATTGGAGGAAATGGAGCTGCGTATTGAGACTCAAAAGCAGACCCTAAATGCTCGGGATGAATCCATTAAGAAGCTTCTGGAAATGTTG CAGAGCAAAGGACTTTCTGCCAAGGCTACCGAGGAAGACCATGAGAGAACAAGACGACTGGCAGAGGCAGAGATGCACGTTCATCACCTA GAAAGCCTTTTGGAGCAGAAGGAAAAAGAGAACAGTATGTTGAGAGAGGTAAAGGCGACACAGGAGGAGAACCGGGAGCTGAGGAGCAGG TGTGAGGAGCTCCACGGGAAGAACCTGGAACTGGGGAAGATCATGGACAGGTTCGAAGAGGTTGTGTACCAGGCCATGGAGGAAGTTCAG AAGCAGAAGGAACTTTCCAAAGCTGAAATCCAGAAAGTTCTAAAAGAAAAAGACCAACTTACCACAGATCTGAACTCCATGGAGAAGTCC TTCTCCGACCTCTTCAAGCGTTTTGAGAAACAGAAAGAGGTGATCGAGGGCTACCGCAAGAACGAAGAGTCACTGAAGAAGTGCGTGGAG GATTACCTGGCAAGGATCACCCAGGAGGGCCAGAGGTACCAAGCCCTGAAGGCCCACGCGGAGGAGAAGCTGCAGCTGGCAAACGAGGAG ATCGCCCAGGTCCGGAGCAAGGCCCAGGCGGAAGCGTTGGCCCTCCAGGCCAGCCTGAGGAAGGAGCAGATGCGCATCCAGTCGCTGGAG AAGACAGTGGAGCAGAAGACTAAAGAGAACGAGGAGCTGACCAGGATCTGCGACGACCTCATCTCCAAGATGGAGAAGATCTGACCTCCA CGGAGCCGCTGTCCCCGCCCCCCTGCTCCCGTCTGTCTGTCCTGTCTGATTCTCTTAGGTGTCATGTTCTTTTTTCTGTCTTGTCTTCAA |
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FusionGenePPI for ERC1_TACC3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ERC1 | YWHAG, TWF2, RAB6A, RAB6B, KBTBD7, IKBKB, MAP3K7, IKBKG, XIAP, ITSN2, RAD23A, SH3KBP1, CHUK, NFKBIA, CUL3, APP, ATP6V0D1, NCBP1, WDR4, ERC2, MYC, PAN2, CDK19, MAPK4, CDK20, LATS2, STK4, GFOD1, ADPRHL2, SNX2, MED4, EWSR1, SRPK2, OFD1, PCM1, CEP104, CEP162, CEP152, CEP128, CEP135, CEP89, CNTRL, FBF1, NINL, NIN, SCLT1, SASS6, DVL2, SLC16A6, KIF23, MAPRE1, RACGAP1, CHST15, PPP1R21, MACROD1, PCGF1, NANOG, POU5F1, NHLRC2, CDH1, EYA4, TSHB, SPERT, TRIM25, BRCA1 | TACC3 | AKAP9, TTF2, NDEL1, MBD2, CKAP5, KAT2A, KAT2B, RAE1, AHCYL1, SRXN1, SEC23A, RAD23B, CPLX1, UBA2, RAD23A, RAB14, SSSCA1, PAICS, SEC24A, AURKA, ARNT2, VPS37C, TBC1D22B, KIZ, ASPSCR1, CIB3, SNX20, FZR1, SNAP29, PLEKHO2, C17orf59, MRE11A, NTRK1, ADAR, CALD1, CUX1, KIF11, PCDH7, VASP, SLBP, NFS1, XPR1, DHRS2, ZER1, SLAIN2, ARX, BOD1L1, ORC3, ENAH, METTL14, RNF123, PDF, PANK2, RNF135, KIAA1804, PRMT9, DEPDC7, RNF168, WDR90, C2orf69, PRR14L, FRYL, FAM111B, MIA3, CRISP2, CORO6, SPERT, EVL, HSPA8, MVK, HSPBP1, OIP5, GTF2E2, ZFC3H1, CDC27 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ERC1_TACC3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ERC1_TACC3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | TACC3 | C0005695 | Bladder Neoplasm | 1 | CTD_human |
| Tgene | TACC3 | C0007138 | Carcinoma, Transitional Cell | 1 | CTD_human |
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