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Fusion gene ID: 11870 |
FusionGeneSummary for EPS15_TTC39A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: EPS15_TTC39A | Fusion gene ID: 11870 | Hgene | Tgene | Gene symbol | EPS15 | TTC39A | Gene ID | 2060 | 22996 |
| Gene name | epidermal growth factor receptor pathway substrate 15 | tetratricopeptide repeat domain 39A | |
| Synonyms | AF-1P|AF1P|MLLT5 | C1orf34|DEME-6 | |
| Cytomap | 1p32.3 | 1p32.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | epidermal growth factor receptor substrate 15ALL1 fused gene from chromosome 1protein AF-1p | tetratricopeptide repeat protein 39ATPR repeat protein 39Adifferentially expressed in MCF7 with estradiol protein 6testicular tissue protein Li 213 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | P42566 | Q5SRH9 | |
| Ensembl transtripts involved in fusion gene | ENST00000371730, ENST00000371733, ENST00000396122, ENST00000493793, | ENST00000447632, ENST00000413473, ENST00000262675, ENST00000451380, ENST00000371750, ENST00000371747, ENST00000262676, ENST00000530004, ENST00000534098, | |
| Fusion gene scores | * DoF score | 10 X 7 X 8=560 | 5 X 4 X 3=60 |
| # samples | 10 | 5 | |
| ** MAII score | log2(10/560*10)=-2.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: EPS15 [Title/Abstract] AND TTC39A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | EPS15 | GO:0048268 | clathrin coat assembly | 12807910 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-25-1623-01A | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000371730 | ENST00000447632 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| In-frame | ENST00000371730 | ENST00000413473 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-5UTR | ENST00000371730 | ENST00000262675 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-5UTR | ENST00000371730 | ENST00000451380 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-5UTR | ENST00000371730 | ENST00000371750 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-5UTR | ENST00000371730 | ENST00000371747 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-5UTR | ENST00000371730 | ENST00000262676 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-intron | ENST00000371730 | ENST00000530004 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-intron | ENST00000371730 | ENST00000534098 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| In-frame | ENST00000371733 | ENST00000447632 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| In-frame | ENST00000371733 | ENST00000413473 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-5UTR | ENST00000371733 | ENST00000262675 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-5UTR | ENST00000371733 | ENST00000451380 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-5UTR | ENST00000371733 | ENST00000371750 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-5UTR | ENST00000371733 | ENST00000371747 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-5UTR | ENST00000371733 | ENST00000262676 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-intron | ENST00000371733 | ENST00000530004 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| 5CDS-intron | ENST00000371733 | ENST00000534098 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-3CDS | ENST00000396122 | ENST00000447632 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-3CDS | ENST00000396122 | ENST00000413473 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-5UTR | ENST00000396122 | ENST00000262675 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-5UTR | ENST00000396122 | ENST00000451380 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-5UTR | ENST00000396122 | ENST00000371750 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-5UTR | ENST00000396122 | ENST00000371747 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-5UTR | ENST00000396122 | ENST00000262676 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-intron | ENST00000396122 | ENST00000530004 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-intron | ENST00000396122 | ENST00000534098 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-3CDS | ENST00000493793 | ENST00000447632 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-3CDS | ENST00000493793 | ENST00000413473 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-5UTR | ENST00000493793 | ENST00000262675 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-5UTR | ENST00000493793 | ENST00000451380 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-5UTR | ENST00000493793 | ENST00000371750 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-5UTR | ENST00000493793 | ENST00000371747 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-5UTR | ENST00000493793 | ENST00000262676 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-intron | ENST00000493793 | ENST00000530004 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
| intron-intron | ENST00000493793 | ENST00000534098 | EPS15 | chr1 | 51912632 | - | TTC39A | chr1 | 51787497 | - |
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FusionProtFeatures for EPS15_TTC39A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| EPS15 | TTC39A |
| Involved in cell growth regulation. May be involved inthe regulation of mitogenic signals and control of cellproliferation. Involved in the internalization of ligand-induciblereceptors of the receptor tyrosine kinase (RTK) type, inparticular EGFR. Plays a role in the assembly of clathrin-coatedpits (CCPs). Acts as a clathrin adapter required for post-Golgitrafficking. Seems to be involved in CCPs maturation includinginvagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1as DAB2-dependent cargo but not TFR seems to require associationwith DAB2. {ECO:0000269|PubMed:16903783,ECO:0000269|PubMed:18362181, ECO:0000269|PubMed:19458185,ECO:0000269|PubMed:22648170}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 173_184 | 265 | 897 | Calcium binding | Note=1 |
| Hgene | EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 236_247 | 265 | 897 | Calcium binding | Note=2 |
| Hgene | EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 128_216 | 265 | 897 | Domain | EH 2 |
| Hgene | EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 15_104 | 265 | 897 | Domain | EH 1 |
| Hgene | EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 160_195 | 265 | 897 | Domain | EF-hand 1 |
| Hgene | EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 223_258 | 265 | 897 | Domain | EF-hand 2 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000262676 | - | 0 | 11 | 315_348 | 10 | 421 | Repeat | Note=TPR 1 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000262676 | - | 0 | 11 | 505_538 | 10 | 421 | Repeat | Note=TPR 2 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000262676 | - | 0 | 11 | 546_579 | 10 | 421 | Repeat | Note=TPR 3 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000413473 | - | 0 | 18 | 315_348 | 17 | 582 | Repeat | Note=TPR 1 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000413473 | - | 0 | 18 | 505_538 | 17 | 582 | Repeat | Note=TPR 2 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000413473 | - | 0 | 18 | 546_579 | 17 | 582 | Repeat | Note=TPR 3 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000447632 | - | 0 | 18 | 315_348 | 14 | 614 | Repeat | Note=TPR 1 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000447632 | - | 0 | 18 | 505_538 | 14 | 614 | Repeat | Note=TPR 2 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000447632 | - | 0 | 18 | 546_579 | 14 | 614 | Repeat | Note=TPR 3 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000451380 | - | 0 | 18 | 315_348 | 13 | 578 | Repeat | Note=TPR 1 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000451380 | - | 0 | 18 | 505_538 | 13 | 578 | Repeat | Note=TPR 2 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000451380 | - | 0 | 18 | 546_579 | 13 | 578 | Repeat | Note=TPR 3 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000530004 | - | 0 | 7 | 315_348 | -72 | 222 | Repeat | Note=TPR 1 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000530004 | - | 0 | 7 | 505_538 | -72 | 222 | Repeat | Note=TPR 2 |
| Tgene | >TTC39A | chr1:51912632 | chr1:51787497 | ENST00000530004 | - | 0 | 7 | 546_579 | -72 | 222 | Repeat | Note=TPR 3 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 768_850 | 265 | 897 | Compositional bias | Note=Pro-rich |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 224_314 | 265 | 897 | Domain | EH 3 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 851_870 | 265 | 897 | Domain | UIM 1 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 877_896 | 265 | 897 | Domain | UIM 2 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 768_774 | 265 | 897 | Motif | Note=SH3-binding |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 599_827 | 265 | 897 | Region | Note=15 X 3 AA repeats of D-P-F |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 599_601 | 265 | 897 | Repeat | Note=1 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 623_625 | 265 | 897 | Repeat | Note=2 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 629_631 | 265 | 897 | Repeat | Note=3 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 634_636 | 265 | 897 | Repeat | Note=4 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 640_642 | 265 | 897 | Repeat | Note=5 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 645_647 | 265 | 897 | Repeat | Note=6 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 651_653 | 265 | 897 | Repeat | Note=7 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 664_666 | 265 | 897 | Repeat | Note=8 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 672_674 | 265 | 897 | Repeat | Note=9 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 692_694 | 265 | 897 | Repeat | Note=10 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 709_711 | 265 | 897 | Repeat | Note=11 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 737_739 | 265 | 897 | Repeat | Note=12 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 798_800 | 265 | 897 | Repeat | Note=13 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 804_806 | 265 | 897 | Repeat | Note=14 |
| Hgene | >EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 825_827 | 265 | 897 | Repeat | Note=15 |
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FusionGeneSequence for EPS15_TTC39A |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_EPS15_ENST00000371730_chr1_51912632_-_TTC39A_ENST00000447632_chr1_51787497_-_865aa MAAAAQLSLTQLSSGNPVYEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS LSSLNLAVPPPRFHDTSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGML DRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWTPES SLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLV NRPTLGQFTEEEIHAEVCYAECLLQRAALTFLQGSSHGGAVRPRALHDPSHACSCPPGPGRQHLFLLQDENMVSFIKGGIKVRNSYQTYK ELDSLVQSSQYCKGENHPHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLTFV LGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLL SKENCWSKATYIYMKAAYLSMFGKEDHKPFGDDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPVPALEMMYIWNGYAV IGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQ >In-frame_EPS15_ENST00000371730_chr1_51912632_-_TTC39A_ENST00000413473_chr1_51787497_-_830aa MAAAAQLSLTQLSSGNPVYEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS LSSLNLAVPPPRFHDTSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGML DRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWTPES SLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLV NRPTLGQFTEEEIHAEVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCKGENHPHFEGGVKLGVGAFNLTL SMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRI EVIKGNIDAAIRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKAAYLSMFGKEDHKPFGDDEV ELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPVPALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDE CLVKLLKGLCLKYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQNYKNYSMESRTHFRIQAATL >In-frame_EPS15_ENST00000371733_chr1_51912632_-_TTC39A_ENST00000447632_chr1_51787497_-_865aa MAAAAQLSLTQLSSGNPVYEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS LSSLNLAVPPPRFHDTSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGML DRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWTPES SLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLV NRPTLGQFTEEEIHAEVCYAECLLQRAALTFLQGSSHGGAVRPRALHDPSHACSCPPGPGRQHLFLLQDENMVSFIKGGIKVRNSYQTYK ELDSLVQSSQYCKGENHPHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLTFV LGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLL SKENCWSKATYIYMKAAYLSMFGKEDHKPFGDDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPVPALEMMYIWNGYAV IGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQ >In-frame_EPS15_ENST00000371733_chr1_51912632_-_TTC39A_ENST00000413473_chr1_51787497_-_830aa MAAAAQLSLTQLSSGNPVYEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS LSSLNLAVPPPRFHDTSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGML DRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWTPES SLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLV NRPTLGQFTEEEIHAEVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCKGENHPHFEGGVKLGVGAFNLTL SMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRI EVIKGNIDAAIRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKAAYLSMFGKEDHKPFGDDEV ELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPVPALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDE CLVKLLKGLCLKYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQNYKNYSMESRTHFRIQAATL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_EPS15_ENST00000371730_chr1_51912632_-_TTC39A_ENST00000447632_chr1_51787497_-_2595nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATACAGGCAAT ACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGATTTAGCC GACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGAAGTTTCA CTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTCATGATACCAGTAGTCCTTTGCTAATCAGTGGAACCTCTGCAGCTGAGCTC CCATGGGCTGTAAAACCTGAAGATAAGGCCAAATATGATGCAATATTTGATAGTTTAAGCCCAGTGAATGGATTTCTGTCTGGTGATAAA GTGAAACCAGTGTTGCTCAACTCTAAGTTACCTGTGGATATCCTTGGAAGAGTTTGGGAGTTGAGTGATATTGACCATGATGGAATGCTT GACAGAGATGAGTTTGCAGTTGCCATGTTTTTGGTATACTGTGCACTGGAGAAAGAACCTGTGCCAATGTCCTTGCCTCCAGCCTTGGTG CCACCATCTAAGAGAAAAACGTGGGTTGTATCCCCTGCAGAAAAAGCTAAATATGATGAAATCTTCCTGAAAACTGATAAAGATATGGAC GGATTTGTGTCTGGATTGGAGGTCCGTGAAATATTCTTGAAAACAGGTTTACCTTCTACCTTACTAGCCCATATATGGACTCCTGAGAGC AGCCTCCATGAGGCCCTGGACCAGTGCATGACCGCCCTGGACCTCTTCCTCACCAACCAGTTCTCAGAAGCACTCAGCTACCTCAAGCCC AGAACCAAGGAAAGCATGTACCACTCACTGACATATGCCACCATCCTGGAGATGCAGGCCATGATGACCTTTGACCCTCAGGACATCCTG CTTGCCGGCAACATGATGAAGGAGGCACAGATGCTGTGTCAGAGGCACCGGAGGAAGTCTTCTGTAACAGATTCCTTCAGCAGCCTGGTG AACCGCCCCACGCTGGGCCAATTCACTGAAGAGGAAATCCACGCTGAGGTCTGCTATGCAGAGTGCCTGCTGCAGCGAGCAGCCCTGACC TTCCTGCAGGGTTCCTCACACGGAGGGGCAGTCAGGCCCAGAGCCTTGCATGATCCCTCTCACGCCTGCAGCTGCCCACCTGGGCCAGGC CGTCAGCATCTTTTCCTCCTGCAGGACGAGAACATGGTGAGCTTCATCAAAGGCGGCATCAAAGTTCGAAACAGCTACCAGACCTACAAG GAGCTGGACAGCCTTGTTCAGTCCTCACAATACTGCAAGGGTGAGAACCACCCGCACTTTGAAGGAGGAGTGAAGCTTGGTGTAGGGGCC TTCAACCTGACACTGTCCATGCTTCCTACTAGGATCCTGAGGCTGTTGGAGTTTGTGGGGTTTTCAGGAAACAAGGACTATGGGCTGCTG CAGCTGGAGGAGGGAGCGTCAGGGCACAGCTTCCGCTCTGTGCTCTGTGTCATGCTCCTGCTGTGCTACCACACCTTCCTCACCTTCGTG CTCGGTACTGGGAACGTCAACATCGAGGAGGCCGAGAAGCTCTTGAAGCCCTACCTGAACCGGTACCCTAAGGGTGCCATCTTCCTGTTC TTTGCAGGGAGGATTGAAGTCATTAAAGGCAACATTGATGCAGCCATCCGGCGTTTCGAGGAGTGCTGTGAGGCCCAGCAGCACTGGAAG CAGTTCCACCACATGTGCTACTGGGAGCTGATGTGGTGCTTCACCTACAAGGGCCAGTGGAAGATGTCCTACTTCTACGCCGACCTGCTC AGCAAGGAGAACTGCTGGTCCAAGGCCACCTACATTTACATGAAGGCCGCCTACCTCAGCATGTTTGGGAAGGAGGACCACAAGCCGTTC GGGGACGACGAAGTGGAATTATTTCGAGCTGTGCCAGGCCTGAAGCTCAAGATTGCTGGGAAATCTCTACCCACAGAGAAGTTTGCCATC CGGAAGTCCCGGCGCTACTTCTCCTCCAACCCTATCTCGCTGCCAGTGCCTGCTCTGGAAATGATGTACATCTGGAACGGCTACGCCGTG ATTGGGAAGCAGCCGAAACTCACGGATGGGATACTTGAGATTATCACTAAGGCTGAAGAGATGCTGGAGAAAGGCCCAGAGAACGAGTAC TCAGTGGATGACGAGTGCTTGGTGAAATTGTTGAAAGGCCTGTGTCTGAAATACCTGGGCCGTGTCCAGGAGGCCGAGGAGAATTTTAGG AGCATCTCTGCCAATGAAAAGAAGATTAAATATGACCACTACTTGATCCCAAACGCCCTGCTGGAGCTGGCCCTGCTGCTTATGGAGCAA GACAGAAACGAAGAGGCCATCAAACTTTTGGAATCTGCCAAGCAAAACTACAAGAATTACTCCATGGAGTCAAGGACACACTTTCGAATC >In-frame_EPS15_ENST00000371730_chr1_51912632_-_TTC39A_ENST00000413473_chr1_51787497_-_2490nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATACAGGCAAT ACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGATTTAGCC GACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGAAGTTTCA CTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTCATGATACCAGTAGTCCTTTGCTAATCAGTGGAACCTCTGCAGCTGAGCTC CCATGGGCTGTAAAACCTGAAGATAAGGCCAAATATGATGCAATATTTGATAGTTTAAGCCCAGTGAATGGATTTCTGTCTGGTGATAAA GTGAAACCAGTGTTGCTCAACTCTAAGTTACCTGTGGATATCCTTGGAAGAGTTTGGGAGTTGAGTGATATTGACCATGATGGAATGCTT GACAGAGATGAGTTTGCAGTTGCCATGTTTTTGGTATACTGTGCACTGGAGAAAGAACCTGTGCCAATGTCCTTGCCTCCAGCCTTGGTG CCACCATCTAAGAGAAAAACGTGGGTTGTATCCCCTGCAGAAAAAGCTAAATATGATGAAATCTTCCTGAAAACTGATAAAGATATGGAC GGATTTGTGTCTGGATTGGAGGTCCGTGAAATATTCTTGAAAACAGGTTTACCTTCTACCTTACTAGCCCATATATGGACTCCTGAGAGC AGCCTCCATGAGGCCCTGGACCAGTGCATGACCGCCCTGGACCTCTTCCTCACCAACCAGTTCTCAGAAGCACTCAGCTACCTCAAGCCC AGAACCAAGGAAAGCATGTACCACTCACTGACATATGCCACCATCCTGGAGATGCAGGCCATGATGACCTTTGACCCTCAGGACATCCTG CTTGCCGGCAACATGATGAAGGAGGCACAGATGCTGTGTCAGAGGCACCGGAGGAAGTCTTCTGTAACAGATTCCTTCAGCAGCCTGGTG AACCGCCCCACGCTGGGCCAATTCACTGAAGAGGAAATCCACGCTGAGGTCTGCTATGCAGAGTGCCTGCTGCAGCGAGCAGCCCTGACC TTCCTGCAGGACGAGAACATGGTGAGCTTCATCAAAGGCGGCATCAAAGTTCGAAACAGCTACCAGACCTACAAGGAGCTGGACAGCCTT GTTCAGTCCTCACAATACTGCAAGGGTGAGAACCACCCGCACTTTGAAGGAGGAGTGAAGCTTGGTGTAGGGGCCTTCAACCTGACACTG TCCATGCTTCCTACTAGGATCCTGAGGCTGTTGGAGTTTGTGGGGTTTTCAGGAAACAAGGACTATGGGCTGCTGCAGCTGGAGGAGGGA GCGTCAGGGCACAGCTTCCGCTCTGTGCTCTGTGTCATGCTCCTGCTGTGCTACCACACCTTCCTCACCTTCGTGCTCGGTACTGGGAAC GTCAACATCGAGGAGGCCGAGAAGCTCTTGAAGCCCTACCTGAACCGGTACCCTAAGGGTGCCATCTTCCTGTTCTTTGCAGGGAGGATT GAAGTCATTAAAGGCAACATTGATGCAGCCATCCGGCGTTTCGAGGAGTGCTGTGAGGCCCAGCAGCACTGGAAGCAGTTCCACCACATG TGCTACTGGGAGCTGATGTGGTGCTTCACCTACAAGGGCCAGTGGAAGATGTCCTACTTCTACGCCGACCTGCTCAGCAAGGAGAACTGC TGGTCCAAGGCCACCTACATTTACATGAAGGCCGCCTACCTCAGCATGTTTGGGAAGGAGGACCACAAGCCGTTCGGGGACGACGAAGTG GAATTATTTCGAGCTGTGCCAGGCCTGAAGCTCAAGATTGCTGGGAAATCTCTACCCACAGAGAAGTTTGCCATCCGGAAGTCCCGGCGC TACTTCTCCTCCAACCCTATCTCGCTGCCAGTGCCTGCTCTGGAAATGATGTACATCTGGAACGGCTACGCCGTGATTGGGAAGCAGCCG AAACTCACGGATGGGATACTTGAGATTATCACTAAGGCTGAAGAGATGCTGGAGAAAGGCCCAGAGAACGAGTACTCAGTGGATGACGAG TGCTTGGTGAAATTGTTGAAAGGCCTGTGTCTGAAATACCTGGGCCGTGTCCAGGAGGCCGAGGAGAATTTTAGGAGCATCTCTGCCAAT GAAAAGAAGATTAAATATGACCACTACTTGATCCCAAACGCCCTGCTGGAGCTGGCCCTGCTGCTTATGGAGCAAGACAGAAACGAAGAG GCCATCAAACTTTTGGAATCTGCCAAGCAAAACTACAAGAATTACTCCATGGAGTCAAGGACACACTTTCGAATCCAGGCAGCCACACTC >In-frame_EPS15_ENST00000371733_chr1_51912632_-_TTC39A_ENST00000447632_chr1_51787497_-_2595nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATACAGGCAAT ACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGATTTAGCC GACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGAAGTTTCA CTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTCATGATACCAGTAGTCCTTTGCTAATCAGTGGAACCTCTGCAGCTGAGCTC CCATGGGCTGTAAAACCTGAAGATAAGGCCAAATATGATGCAATATTTGATAGTTTAAGCCCAGTGAATGGATTTCTGTCTGGTGATAAA GTGAAACCAGTGTTGCTCAACTCTAAGTTACCTGTGGATATCCTTGGAAGAGTTTGGGAGTTGAGTGATATTGACCATGATGGAATGCTT GACAGAGATGAGTTTGCAGTTGCCATGTTTTTGGTATACTGTGCACTGGAGAAAGAACCTGTGCCAATGTCCTTGCCTCCAGCCTTGGTG CCACCATCTAAGAGAAAAACGTGGGTTGTATCCCCTGCAGAAAAAGCTAAATATGATGAAATCTTCCTGAAAACTGATAAAGATATGGAC GGATTTGTGTCTGGATTGGAGGTCCGTGAAATATTCTTGAAAACAGGTTTACCTTCTACCTTACTAGCCCATATATGGACTCCTGAGAGC AGCCTCCATGAGGCCCTGGACCAGTGCATGACCGCCCTGGACCTCTTCCTCACCAACCAGTTCTCAGAAGCACTCAGCTACCTCAAGCCC AGAACCAAGGAAAGCATGTACCACTCACTGACATATGCCACCATCCTGGAGATGCAGGCCATGATGACCTTTGACCCTCAGGACATCCTG CTTGCCGGCAACATGATGAAGGAGGCACAGATGCTGTGTCAGAGGCACCGGAGGAAGTCTTCTGTAACAGATTCCTTCAGCAGCCTGGTG AACCGCCCCACGCTGGGCCAATTCACTGAAGAGGAAATCCACGCTGAGGTCTGCTATGCAGAGTGCCTGCTGCAGCGAGCAGCCCTGACC TTCCTGCAGGGTTCCTCACACGGAGGGGCAGTCAGGCCCAGAGCCTTGCATGATCCCTCTCACGCCTGCAGCTGCCCACCTGGGCCAGGC CGTCAGCATCTTTTCCTCCTGCAGGACGAGAACATGGTGAGCTTCATCAAAGGCGGCATCAAAGTTCGAAACAGCTACCAGACCTACAAG GAGCTGGACAGCCTTGTTCAGTCCTCACAATACTGCAAGGGTGAGAACCACCCGCACTTTGAAGGAGGAGTGAAGCTTGGTGTAGGGGCC TTCAACCTGACACTGTCCATGCTTCCTACTAGGATCCTGAGGCTGTTGGAGTTTGTGGGGTTTTCAGGAAACAAGGACTATGGGCTGCTG CAGCTGGAGGAGGGAGCGTCAGGGCACAGCTTCCGCTCTGTGCTCTGTGTCATGCTCCTGCTGTGCTACCACACCTTCCTCACCTTCGTG CTCGGTACTGGGAACGTCAACATCGAGGAGGCCGAGAAGCTCTTGAAGCCCTACCTGAACCGGTACCCTAAGGGTGCCATCTTCCTGTTC TTTGCAGGGAGGATTGAAGTCATTAAAGGCAACATTGATGCAGCCATCCGGCGTTTCGAGGAGTGCTGTGAGGCCCAGCAGCACTGGAAG CAGTTCCACCACATGTGCTACTGGGAGCTGATGTGGTGCTTCACCTACAAGGGCCAGTGGAAGATGTCCTACTTCTACGCCGACCTGCTC AGCAAGGAGAACTGCTGGTCCAAGGCCACCTACATTTACATGAAGGCCGCCTACCTCAGCATGTTTGGGAAGGAGGACCACAAGCCGTTC GGGGACGACGAAGTGGAATTATTTCGAGCTGTGCCAGGCCTGAAGCTCAAGATTGCTGGGAAATCTCTACCCACAGAGAAGTTTGCCATC CGGAAGTCCCGGCGCTACTTCTCCTCCAACCCTATCTCGCTGCCAGTGCCTGCTCTGGAAATGATGTACATCTGGAACGGCTACGCCGTG ATTGGGAAGCAGCCGAAACTCACGGATGGGATACTTGAGATTATCACTAAGGCTGAAGAGATGCTGGAGAAAGGCCCAGAGAACGAGTAC TCAGTGGATGACGAGTGCTTGGTGAAATTGTTGAAAGGCCTGTGTCTGAAATACCTGGGCCGTGTCCAGGAGGCCGAGGAGAATTTTAGG AGCATCTCTGCCAATGAAAAGAAGATTAAATATGACCACTACTTGATCCCAAACGCCCTGCTGGAGCTGGCCCTGCTGCTTATGGAGCAA GACAGAAACGAAGAGGCCATCAAACTTTTGGAATCTGCCAAGCAAAACTACAAGAATTACTCCATGGAGTCAAGGACACACTTTCGAATC >In-frame_EPS15_ENST00000371733_chr1_51912632_-_TTC39A_ENST00000413473_chr1_51787497_-_2490nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATACAGGCAAT ACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGATTTAGCC GACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGAAGTTTCA CTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTCATGATACCAGTAGTCCTTTGCTAATCAGTGGAACCTCTGCAGCTGAGCTC CCATGGGCTGTAAAACCTGAAGATAAGGCCAAATATGATGCAATATTTGATAGTTTAAGCCCAGTGAATGGATTTCTGTCTGGTGATAAA GTGAAACCAGTGTTGCTCAACTCTAAGTTACCTGTGGATATCCTTGGAAGAGTTTGGGAGTTGAGTGATATTGACCATGATGGAATGCTT GACAGAGATGAGTTTGCAGTTGCCATGTTTTTGGTATACTGTGCACTGGAGAAAGAACCTGTGCCAATGTCCTTGCCTCCAGCCTTGGTG CCACCATCTAAGAGAAAAACGTGGGTTGTATCCCCTGCAGAAAAAGCTAAATATGATGAAATCTTCCTGAAAACTGATAAAGATATGGAC GGATTTGTGTCTGGATTGGAGGTCCGTGAAATATTCTTGAAAACAGGTTTACCTTCTACCTTACTAGCCCATATATGGACTCCTGAGAGC AGCCTCCATGAGGCCCTGGACCAGTGCATGACCGCCCTGGACCTCTTCCTCACCAACCAGTTCTCAGAAGCACTCAGCTACCTCAAGCCC AGAACCAAGGAAAGCATGTACCACTCACTGACATATGCCACCATCCTGGAGATGCAGGCCATGATGACCTTTGACCCTCAGGACATCCTG CTTGCCGGCAACATGATGAAGGAGGCACAGATGCTGTGTCAGAGGCACCGGAGGAAGTCTTCTGTAACAGATTCCTTCAGCAGCCTGGTG AACCGCCCCACGCTGGGCCAATTCACTGAAGAGGAAATCCACGCTGAGGTCTGCTATGCAGAGTGCCTGCTGCAGCGAGCAGCCCTGACC TTCCTGCAGGACGAGAACATGGTGAGCTTCATCAAAGGCGGCATCAAAGTTCGAAACAGCTACCAGACCTACAAGGAGCTGGACAGCCTT GTTCAGTCCTCACAATACTGCAAGGGTGAGAACCACCCGCACTTTGAAGGAGGAGTGAAGCTTGGTGTAGGGGCCTTCAACCTGACACTG TCCATGCTTCCTACTAGGATCCTGAGGCTGTTGGAGTTTGTGGGGTTTTCAGGAAACAAGGACTATGGGCTGCTGCAGCTGGAGGAGGGA GCGTCAGGGCACAGCTTCCGCTCTGTGCTCTGTGTCATGCTCCTGCTGTGCTACCACACCTTCCTCACCTTCGTGCTCGGTACTGGGAAC GTCAACATCGAGGAGGCCGAGAAGCTCTTGAAGCCCTACCTGAACCGGTACCCTAAGGGTGCCATCTTCCTGTTCTTTGCAGGGAGGATT GAAGTCATTAAAGGCAACATTGATGCAGCCATCCGGCGTTTCGAGGAGTGCTGTGAGGCCCAGCAGCACTGGAAGCAGTTCCACCACATG TGCTACTGGGAGCTGATGTGGTGCTTCACCTACAAGGGCCAGTGGAAGATGTCCTACTTCTACGCCGACCTGCTCAGCAAGGAGAACTGC TGGTCCAAGGCCACCTACATTTACATGAAGGCCGCCTACCTCAGCATGTTTGGGAAGGAGGACCACAAGCCGTTCGGGGACGACGAAGTG GAATTATTTCGAGCTGTGCCAGGCCTGAAGCTCAAGATTGCTGGGAAATCTCTACCCACAGAGAAGTTTGCCATCCGGAAGTCCCGGCGC TACTTCTCCTCCAACCCTATCTCGCTGCCAGTGCCTGCTCTGGAAATGATGTACATCTGGAACGGCTACGCCGTGATTGGGAAGCAGCCG AAACTCACGGATGGGATACTTGAGATTATCACTAAGGCTGAAGAGATGCTGGAGAAAGGCCCAGAGAACGAGTACTCAGTGGATGACGAG TGCTTGGTGAAATTGTTGAAAGGCCTGTGTCTGAAATACCTGGGCCGTGTCCAGGAGGCCGAGGAGAATTTTAGGAGCATCTCTGCCAAT GAAAAGAAGATTAAATATGACCACTACTTGATCCCAAACGCCCTGCTGGAGCTGGCCCTGCTGCTTATGGAGCAAGACAGAAACGAAGAG GCCATCAAACTTTTGGAATCTGCCAAGCAAAACTACAAGAATTACTCCATGGAGTCAAGGACACACTTTCGAATCCAGGCAGCCACACTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_EPS15_ENST00000371730_chr1_51912632_-_TTC39A_ENST00000447632_chr1_51787497_-_3504nt TGGAAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGA TACAGGCAATACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTG GGATTTAGCCGACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATT GGAAGTTTCACTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTCATGATACCAGTAGTCCTTTGCTAATCAGTGGAACCTCTGC AGCTGAGCTCCCATGGGCTGTAAAACCTGAAGATAAGGCCAAATATGATGCAATATTTGATAGTTTAAGCCCAGTGAATGGATTTCTGTC TGGTGATAAAGTGAAACCAGTGTTGCTCAACTCTAAGTTACCTGTGGATATCCTTGGAAGAGTTTGGGAGTTGAGTGATATTGACCATGA TGGAATGCTTGACAGAGATGAGTTTGCAGTTGCCATGTTTTTGGTATACTGTGCACTGGAGAAAGAACCTGTGCCAATGTCCTTGCCTCC AGCCTTGGTGCCACCATCTAAGAGAAAAACGTGGGTTGTATCCCCTGCAGAAAAAGCTAAATATGATGAAATCTTCCTGAAAACTGATAA AGATATGGACGGATTTGTGTCTGGATTGGAGGTCCGTGAAATATTCTTGAAAACAGGTTTACCTTCTACCTTACTAGCCCATATATGGAC TCCTGAGAGCAGCCTCCATGAGGCCCTGGACCAGTGCATGACCGCCCTGGACCTCTTCCTCACCAACCAGTTCTCAGAAGCACTCAGCTA CCTCAAGCCCAGAACCAAGGAAAGCATGTACCACTCACTGACATATGCCACCATCCTGGAGATGCAGGCCATGATGACCTTTGACCCTCA GGACATCCTGCTTGCCGGCAACATGATGAAGGAGGCACAGATGCTGTGTCAGAGGCACCGGAGGAAGTCTTCTGTAACAGATTCCTTCAG CAGCCTGGTGAACCGCCCCACGCTGGGCCAATTCACTGAAGAGGAAATCCACGCTGAGGTCTGCTATGCAGAGTGCCTGCTGCAGCGAGC AGCCCTGACCTTCCTGCAGGGTTCCTCACACGGAGGGGCAGTCAGGCCCAGAGCCTTGCATGATCCCTCTCACGCCTGCAGCTGCCCACC TGGGCCAGGCCGTCAGCATCTTTTCCTCCTGCAGGACGAGAACATGGTGAGCTTCATCAAAGGCGGCATCAAAGTTCGAAACAGCTACCA GACCTACAAGGAGCTGGACAGCCTTGTTCAGTCCTCACAATACTGCAAGGGTGAGAACCACCCGCACTTTGAAGGAGGAGTGAAGCTTGG TGTAGGGGCCTTCAACCTGACACTGTCCATGCTTCCTACTAGGATCCTGAGGCTGTTGGAGTTTGTGGGGTTTTCAGGAAACAAGGACTA TGGGCTGCTGCAGCTGGAGGAGGGAGCGTCAGGGCACAGCTTCCGCTCTGTGCTCTGTGTCATGCTCCTGCTGTGCTACCACACCTTCCT CACCTTCGTGCTCGGTACTGGGAACGTCAACATCGAGGAGGCCGAGAAGCTCTTGAAGCCCTACCTGAACCGGTACCCTAAGGGTGCCAT CTTCCTGTTCTTTGCAGGGAGGATTGAAGTCATTAAAGGCAACATTGATGCAGCCATCCGGCGTTTCGAGGAGTGCTGTGAGGCCCAGCA GCACTGGAAGCAGTTCCACCACATGTGCTACTGGGAGCTGATGTGGTGCTTCACCTACAAGGGCCAGTGGAAGATGTCCTACTTCTACGC CGACCTGCTCAGCAAGGAGAACTGCTGGTCCAAGGCCACCTACATTTACATGAAGGCCGCCTACCTCAGCATGTTTGGGAAGGAGGACCA CAAGCCGTTCGGGGACGACGAAGTGGAATTATTTCGAGCTGTGCCAGGCCTGAAGCTCAAGATTGCTGGGAAATCTCTACCCACAGAGAA GTTTGCCATCCGGAAGTCCCGGCGCTACTTCTCCTCCAACCCTATCTCGCTGCCAGTGCCTGCTCTGGAAATGATGTACATCTGGAACGG CTACGCCGTGATTGGGAAGCAGCCGAAACTCACGGATGGGATACTTGAGATTATCACTAAGGCTGAAGAGATGCTGGAGAAAGGCCCAGA GAACGAGTACTCAGTGGATGACGAGTGCTTGGTGAAATTGTTGAAAGGCCTGTGTCTGAAATACCTGGGCCGTGTCCAGGAGGCCGAGGA GAATTTTAGGAGCATCTCTGCCAATGAAAAGAAGATTAAATATGACCACTACTTGATCCCAAACGCCCTGCTGGAGCTGGCCCTGCTGCT TATGGAGCAAGACAGAAACGAAGAGGCCATCAAACTTTTGGAATCTGCCAAGCAAAACTACAAGAATTACTCCATGGAGTCAAGGACACA CTTTCGAATCCAGGCAGCCACACTCCAAGCCAAGTCTTCCCTAGAGAACAGCAGCAGATCCATGGTCTCATCAGTGTCCTTGTAGCTTTG TGCAGCAGTTCCGGGCTGGAAGACAGAGACAGCTGGACAGAGCTCCTGAAAACATTTCAAAATACCCCCTCCCCCTGCCCTGCCCTGCCT TTGGGGTCCACCGGCACTCCAGTTGGATGGCACAACATAGTGTATCCGTGCAGAAGCCGAGCTGGCATTTTCACCAGTGTAGCCAAGGGC CTTTGCCAAGGGCAGAGCAGGTGGAGCCCTCTGCCTGCCCTATCACACATACGGGTACTTGCTTTTCACTGTGATGTTTAAGAGAATGTA TGAACAGTTTACATTTTCCTTAGAAATACATTGATGGGATCACAGTTGGCTTTAAAAACCAACAACAATCAACCACCTGTAAGTCTTTGT CTTCACCTATTATCATCTGGAGGTAAATCTCTTTATATGATGATGCCAAAGGGCAAATTGCTTTTCAAATTCAGCAAGTTCTCAGCTTGT GTGACGGAAGGTCCTTCAGAGGACCTGAGGAATGCCTGGGAGAGGCTAAGCCTCAGGCTTCAATGCTTCTGGGGTTGGGCATGAGGATGT ACACAGACACCCACTACCTTACTACTCACACTTCATTTCACTCCTTTTGTAAATTTCCAATTTAAAAATCAAGCACGTCTTTTTAGTGAG ATAAAATCTGAGCTCTTCTGTAGAAAAATCAATCTCTACCAGTAGAAAATGCCAGGGCTTGATGGAAGAGCTGTGTAGCCCTTTCTATGC CAAAGCCAGGAAATTTGGGGGGCAGGAGGAGGTTCTCAGAATCCAGTCTGTATCTTTGCTGTATGCCAAACTGAAACCACTGGGAATAAT >In-frame_EPS15_ENST00000371730_chr1_51912632_-_TTC39A_ENST00000413473_chr1_51787497_-_3399nt TGGAAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGA TACAGGCAATACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTG GGATTTAGCCGACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATT GGAAGTTTCACTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTCATGATACCAGTAGTCCTTTGCTAATCAGTGGAACCTCTGC AGCTGAGCTCCCATGGGCTGTAAAACCTGAAGATAAGGCCAAATATGATGCAATATTTGATAGTTTAAGCCCAGTGAATGGATTTCTGTC TGGTGATAAAGTGAAACCAGTGTTGCTCAACTCTAAGTTACCTGTGGATATCCTTGGAAGAGTTTGGGAGTTGAGTGATATTGACCATGA TGGAATGCTTGACAGAGATGAGTTTGCAGTTGCCATGTTTTTGGTATACTGTGCACTGGAGAAAGAACCTGTGCCAATGTCCTTGCCTCC AGCCTTGGTGCCACCATCTAAGAGAAAAACGTGGGTTGTATCCCCTGCAGAAAAAGCTAAATATGATGAAATCTTCCTGAAAACTGATAA AGATATGGACGGATTTGTGTCTGGATTGGAGGTCCGTGAAATATTCTTGAAAACAGGTTTACCTTCTACCTTACTAGCCCATATATGGAC TCCTGAGAGCAGCCTCCATGAGGCCCTGGACCAGTGCATGACCGCCCTGGACCTCTTCCTCACCAACCAGTTCTCAGAAGCACTCAGCTA CCTCAAGCCCAGAACCAAGGAAAGCATGTACCACTCACTGACATATGCCACCATCCTGGAGATGCAGGCCATGATGACCTTTGACCCTCA GGACATCCTGCTTGCCGGCAACATGATGAAGGAGGCACAGATGCTGTGTCAGAGGCACCGGAGGAAGTCTTCTGTAACAGATTCCTTCAG CAGCCTGGTGAACCGCCCCACGCTGGGCCAATTCACTGAAGAGGAAATCCACGCTGAGGTCTGCTATGCAGAGTGCCTGCTGCAGCGAGC AGCCCTGACCTTCCTGCAGGACGAGAACATGGTGAGCTTCATCAAAGGCGGCATCAAAGTTCGAAACAGCTACCAGACCTACAAGGAGCT GGACAGCCTTGTTCAGTCCTCACAATACTGCAAGGGTGAGAACCACCCGCACTTTGAAGGAGGAGTGAAGCTTGGTGTAGGGGCCTTCAA CCTGACACTGTCCATGCTTCCTACTAGGATCCTGAGGCTGTTGGAGTTTGTGGGGTTTTCAGGAAACAAGGACTATGGGCTGCTGCAGCT GGAGGAGGGAGCGTCAGGGCACAGCTTCCGCTCTGTGCTCTGTGTCATGCTCCTGCTGTGCTACCACACCTTCCTCACCTTCGTGCTCGG TACTGGGAACGTCAACATCGAGGAGGCCGAGAAGCTCTTGAAGCCCTACCTGAACCGGTACCCTAAGGGTGCCATCTTCCTGTTCTTTGC AGGGAGGATTGAAGTCATTAAAGGCAACATTGATGCAGCCATCCGGCGTTTCGAGGAGTGCTGTGAGGCCCAGCAGCACTGGAAGCAGTT CCACCACATGTGCTACTGGGAGCTGATGTGGTGCTTCACCTACAAGGGCCAGTGGAAGATGTCCTACTTCTACGCCGACCTGCTCAGCAA GGAGAACTGCTGGTCCAAGGCCACCTACATTTACATGAAGGCCGCCTACCTCAGCATGTTTGGGAAGGAGGACCACAAGCCGTTCGGGGA CGACGAAGTGGAATTATTTCGAGCTGTGCCAGGCCTGAAGCTCAAGATTGCTGGGAAATCTCTACCCACAGAGAAGTTTGCCATCCGGAA GTCCCGGCGCTACTTCTCCTCCAACCCTATCTCGCTGCCAGTGCCTGCTCTGGAAATGATGTACATCTGGAACGGCTACGCCGTGATTGG GAAGCAGCCGAAACTCACGGATGGGATACTTGAGATTATCACTAAGGCTGAAGAGATGCTGGAGAAAGGCCCAGAGAACGAGTACTCAGT GGATGACGAGTGCTTGGTGAAATTGTTGAAAGGCCTGTGTCTGAAATACCTGGGCCGTGTCCAGGAGGCCGAGGAGAATTTTAGGAGCAT CTCTGCCAATGAAAAGAAGATTAAATATGACCACTACTTGATCCCAAACGCCCTGCTGGAGCTGGCCCTGCTGCTTATGGAGCAAGACAG AAACGAAGAGGCCATCAAACTTTTGGAATCTGCCAAGCAAAACTACAAGAATTACTCCATGGAGTCAAGGACACACTTTCGAATCCAGGC AGCCACACTCCAAGCCAAGTCTTCCCTAGAGAACAGCAGCAGATCCATGGTCTCATCAGTGTCCTTGTAGCTTTGTGCAGCAGTTCCGGG CTGGAAGACAGAGACAGCTGGACAGAGCTCCTGAAAACATTTCAAAATACCCCCTCCCCCTGCCCTGCCCTGCCTTTGGGGTCCACCGGC ACTCCAGTTGGATGGCACAACATAGTGTATCCGTGCAGAAGCCGAGCTGGCATTTTCACCAGTGTAGCCAAGGGCCTTTGCCAAGGGCAG AGCAGGTGGAGCCCTCTGCCTGCCCTATCACACATACGGGTACTTGCTTTTCACTGTGATGTTTAAGAGAATGTATGAACAGTTTACATT TTCCTTAGAAATACATTGATGGGATCACAGTTGGCTTTAAAAACCAACAACAATCAACCACCTGTAAGTCTTTGTCTTCACCTATTATCA TCTGGAGGTAAATCTCTTTATATGATGATGCCAAAGGGCAAATTGCTTTTCAAATTCAGCAAGTTCTCAGCTTGTGTGACGGAAGGTCCT TCAGAGGACCTGAGGAATGCCTGGGAGAGGCTAAGCCTCAGGCTTCAATGCTTCTGGGGTTGGGCATGAGGATGTACACAGACACCCACT ACCTTACTACTCACACTTCATTTCACTCCTTTTGTAAATTTCCAATTTAAAAATCAAGCACGTCTTTTTAGTGAGATAAAATCTGAGCTC TTCTGTAGAAAAATCAATCTCTACCAGTAGAAAATGCCAGGGCTTGATGGAAGAGCTGTGTAGCCCTTTCTATGCCAAAGCCAGGAAATT TGGGGGGCAGGAGGAGGTTCTCAGAATCCAGTCTGTATCTTTGCTGTATGCCAAACTGAAACCACTGGGAATAATTTATGAAACATAAAA >In-frame_EPS15_ENST00000371733_chr1_51912632_-_TTC39A_ENST00000447632_chr1_51787497_-_3591nt GCCCCGGCCTCGCCTGCGGCCGCTCCCTCCGCCTCCTCCCCGCCCCGAGCCCCAGTCAGCCCGTCTTCCTTCCCCTCCCTTGCATGATGG AAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATAC AGGCAATACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGA TTTAGCCGACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGA AGTTTCACTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTCATGATACCAGTAGTCCTTTGCTAATCAGTGGAACCTCTGCAGC TGAGCTCCCATGGGCTGTAAAACCTGAAGATAAGGCCAAATATGATGCAATATTTGATAGTTTAAGCCCAGTGAATGGATTTCTGTCTGG TGATAAAGTGAAACCAGTGTTGCTCAACTCTAAGTTACCTGTGGATATCCTTGGAAGAGTTTGGGAGTTGAGTGATATTGACCATGATGG AATGCTTGACAGAGATGAGTTTGCAGTTGCCATGTTTTTGGTATACTGTGCACTGGAGAAAGAACCTGTGCCAATGTCCTTGCCTCCAGC CTTGGTGCCACCATCTAAGAGAAAAACGTGGGTTGTATCCCCTGCAGAAAAAGCTAAATATGATGAAATCTTCCTGAAAACTGATAAAGA TATGGACGGATTTGTGTCTGGATTGGAGGTCCGTGAAATATTCTTGAAAACAGGTTTACCTTCTACCTTACTAGCCCATATATGGACTCC TGAGAGCAGCCTCCATGAGGCCCTGGACCAGTGCATGACCGCCCTGGACCTCTTCCTCACCAACCAGTTCTCAGAAGCACTCAGCTACCT CAAGCCCAGAACCAAGGAAAGCATGTACCACTCACTGACATATGCCACCATCCTGGAGATGCAGGCCATGATGACCTTTGACCCTCAGGA CATCCTGCTTGCCGGCAACATGATGAAGGAGGCACAGATGCTGTGTCAGAGGCACCGGAGGAAGTCTTCTGTAACAGATTCCTTCAGCAG CCTGGTGAACCGCCCCACGCTGGGCCAATTCACTGAAGAGGAAATCCACGCTGAGGTCTGCTATGCAGAGTGCCTGCTGCAGCGAGCAGC CCTGACCTTCCTGCAGGGTTCCTCACACGGAGGGGCAGTCAGGCCCAGAGCCTTGCATGATCCCTCTCACGCCTGCAGCTGCCCACCTGG GCCAGGCCGTCAGCATCTTTTCCTCCTGCAGGACGAGAACATGGTGAGCTTCATCAAAGGCGGCATCAAAGTTCGAAACAGCTACCAGAC CTACAAGGAGCTGGACAGCCTTGTTCAGTCCTCACAATACTGCAAGGGTGAGAACCACCCGCACTTTGAAGGAGGAGTGAAGCTTGGTGT AGGGGCCTTCAACCTGACACTGTCCATGCTTCCTACTAGGATCCTGAGGCTGTTGGAGTTTGTGGGGTTTTCAGGAAACAAGGACTATGG GCTGCTGCAGCTGGAGGAGGGAGCGTCAGGGCACAGCTTCCGCTCTGTGCTCTGTGTCATGCTCCTGCTGTGCTACCACACCTTCCTCAC CTTCGTGCTCGGTACTGGGAACGTCAACATCGAGGAGGCCGAGAAGCTCTTGAAGCCCTACCTGAACCGGTACCCTAAGGGTGCCATCTT CCTGTTCTTTGCAGGGAGGATTGAAGTCATTAAAGGCAACATTGATGCAGCCATCCGGCGTTTCGAGGAGTGCTGTGAGGCCCAGCAGCA CTGGAAGCAGTTCCACCACATGTGCTACTGGGAGCTGATGTGGTGCTTCACCTACAAGGGCCAGTGGAAGATGTCCTACTTCTACGCCGA CCTGCTCAGCAAGGAGAACTGCTGGTCCAAGGCCACCTACATTTACATGAAGGCCGCCTACCTCAGCATGTTTGGGAAGGAGGACCACAA GCCGTTCGGGGACGACGAAGTGGAATTATTTCGAGCTGTGCCAGGCCTGAAGCTCAAGATTGCTGGGAAATCTCTACCCACAGAGAAGTT TGCCATCCGGAAGTCCCGGCGCTACTTCTCCTCCAACCCTATCTCGCTGCCAGTGCCTGCTCTGGAAATGATGTACATCTGGAACGGCTA CGCCGTGATTGGGAAGCAGCCGAAACTCACGGATGGGATACTTGAGATTATCACTAAGGCTGAAGAGATGCTGGAGAAAGGCCCAGAGAA CGAGTACTCAGTGGATGACGAGTGCTTGGTGAAATTGTTGAAAGGCCTGTGTCTGAAATACCTGGGCCGTGTCCAGGAGGCCGAGGAGAA TTTTAGGAGCATCTCTGCCAATGAAAAGAAGATTAAATATGACCACTACTTGATCCCAAACGCCCTGCTGGAGCTGGCCCTGCTGCTTAT GGAGCAAGACAGAAACGAAGAGGCCATCAAACTTTTGGAATCTGCCAAGCAAAACTACAAGAATTACTCCATGGAGTCAAGGACACACTT TCGAATCCAGGCAGCCACACTCCAAGCCAAGTCTTCCCTAGAGAACAGCAGCAGATCCATGGTCTCATCAGTGTCCTTGTAGCTTTGTGC AGCAGTTCCGGGCTGGAAGACAGAGACAGCTGGACAGAGCTCCTGAAAACATTTCAAAATACCCCCTCCCCCTGCCCTGCCCTGCCTTTG GGGTCCACCGGCACTCCAGTTGGATGGCACAACATAGTGTATCCGTGCAGAAGCCGAGCTGGCATTTTCACCAGTGTAGCCAAGGGCCTT TGCCAAGGGCAGAGCAGGTGGAGCCCTCTGCCTGCCCTATCACACATACGGGTACTTGCTTTTCACTGTGATGTTTAAGAGAATGTATGA ACAGTTTACATTTTCCTTAGAAATACATTGATGGGATCACAGTTGGCTTTAAAAACCAACAACAATCAACCACCTGTAAGTCTTTGTCTT CACCTATTATCATCTGGAGGTAAATCTCTTTATATGATGATGCCAAAGGGCAAATTGCTTTTCAAATTCAGCAAGTTCTCAGCTTGTGTG ACGGAAGGTCCTTCAGAGGACCTGAGGAATGCCTGGGAGAGGCTAAGCCTCAGGCTTCAATGCTTCTGGGGTTGGGCATGAGGATGTACA CAGACACCCACTACCTTACTACTCACACTTCATTTCACTCCTTTTGTAAATTTCCAATTTAAAAATCAAGCACGTCTTTTTAGTGAGATA AAATCTGAGCTCTTCTGTAGAAAAATCAATCTCTACCAGTAGAAAATGCCAGGGCTTGATGGAAGAGCTGTGTAGCCCTTTCTATGCCAA AGCCAGGAAATTTGGGGGGCAGGAGGAGGTTCTCAGAATCCAGTCTGTATCTTTGCTGTATGCCAAACTGAAACCACTGGGAATAATTTA >In-frame_EPS15_ENST00000371733_chr1_51912632_-_TTC39A_ENST00000413473_chr1_51787497_-_3486nt GCCCCGGCCTCGCCTGCGGCCGCTCCCTCCGCCTCCTCCCCGCCCCGAGCCCCAGTCAGCCCGTCTTCCTTCCCCTCCCTTGCATGATGG AAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATAC AGGCAATACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGA TTTAGCCGACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGA AGTTTCACTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTCATGATACCAGTAGTCCTTTGCTAATCAGTGGAACCTCTGCAGC TGAGCTCCCATGGGCTGTAAAACCTGAAGATAAGGCCAAATATGATGCAATATTTGATAGTTTAAGCCCAGTGAATGGATTTCTGTCTGG TGATAAAGTGAAACCAGTGTTGCTCAACTCTAAGTTACCTGTGGATATCCTTGGAAGAGTTTGGGAGTTGAGTGATATTGACCATGATGG AATGCTTGACAGAGATGAGTTTGCAGTTGCCATGTTTTTGGTATACTGTGCACTGGAGAAAGAACCTGTGCCAATGTCCTTGCCTCCAGC CTTGGTGCCACCATCTAAGAGAAAAACGTGGGTTGTATCCCCTGCAGAAAAAGCTAAATATGATGAAATCTTCCTGAAAACTGATAAAGA TATGGACGGATTTGTGTCTGGATTGGAGGTCCGTGAAATATTCTTGAAAACAGGTTTACCTTCTACCTTACTAGCCCATATATGGACTCC TGAGAGCAGCCTCCATGAGGCCCTGGACCAGTGCATGACCGCCCTGGACCTCTTCCTCACCAACCAGTTCTCAGAAGCACTCAGCTACCT CAAGCCCAGAACCAAGGAAAGCATGTACCACTCACTGACATATGCCACCATCCTGGAGATGCAGGCCATGATGACCTTTGACCCTCAGGA CATCCTGCTTGCCGGCAACATGATGAAGGAGGCACAGATGCTGTGTCAGAGGCACCGGAGGAAGTCTTCTGTAACAGATTCCTTCAGCAG CCTGGTGAACCGCCCCACGCTGGGCCAATTCACTGAAGAGGAAATCCACGCTGAGGTCTGCTATGCAGAGTGCCTGCTGCAGCGAGCAGC CCTGACCTTCCTGCAGGACGAGAACATGGTGAGCTTCATCAAAGGCGGCATCAAAGTTCGAAACAGCTACCAGACCTACAAGGAGCTGGA CAGCCTTGTTCAGTCCTCACAATACTGCAAGGGTGAGAACCACCCGCACTTTGAAGGAGGAGTGAAGCTTGGTGTAGGGGCCTTCAACCT GACACTGTCCATGCTTCCTACTAGGATCCTGAGGCTGTTGGAGTTTGTGGGGTTTTCAGGAAACAAGGACTATGGGCTGCTGCAGCTGGA GGAGGGAGCGTCAGGGCACAGCTTCCGCTCTGTGCTCTGTGTCATGCTCCTGCTGTGCTACCACACCTTCCTCACCTTCGTGCTCGGTAC TGGGAACGTCAACATCGAGGAGGCCGAGAAGCTCTTGAAGCCCTACCTGAACCGGTACCCTAAGGGTGCCATCTTCCTGTTCTTTGCAGG GAGGATTGAAGTCATTAAAGGCAACATTGATGCAGCCATCCGGCGTTTCGAGGAGTGCTGTGAGGCCCAGCAGCACTGGAAGCAGTTCCA CCACATGTGCTACTGGGAGCTGATGTGGTGCTTCACCTACAAGGGCCAGTGGAAGATGTCCTACTTCTACGCCGACCTGCTCAGCAAGGA GAACTGCTGGTCCAAGGCCACCTACATTTACATGAAGGCCGCCTACCTCAGCATGTTTGGGAAGGAGGACCACAAGCCGTTCGGGGACGA CGAAGTGGAATTATTTCGAGCTGTGCCAGGCCTGAAGCTCAAGATTGCTGGGAAATCTCTACCCACAGAGAAGTTTGCCATCCGGAAGTC CCGGCGCTACTTCTCCTCCAACCCTATCTCGCTGCCAGTGCCTGCTCTGGAAATGATGTACATCTGGAACGGCTACGCCGTGATTGGGAA GCAGCCGAAACTCACGGATGGGATACTTGAGATTATCACTAAGGCTGAAGAGATGCTGGAGAAAGGCCCAGAGAACGAGTACTCAGTGGA TGACGAGTGCTTGGTGAAATTGTTGAAAGGCCTGTGTCTGAAATACCTGGGCCGTGTCCAGGAGGCCGAGGAGAATTTTAGGAGCATCTC TGCCAATGAAAAGAAGATTAAATATGACCACTACTTGATCCCAAACGCCCTGCTGGAGCTGGCCCTGCTGCTTATGGAGCAAGACAGAAA CGAAGAGGCCATCAAACTTTTGGAATCTGCCAAGCAAAACTACAAGAATTACTCCATGGAGTCAAGGACACACTTTCGAATCCAGGCAGC CACACTCCAAGCCAAGTCTTCCCTAGAGAACAGCAGCAGATCCATGGTCTCATCAGTGTCCTTGTAGCTTTGTGCAGCAGTTCCGGGCTG GAAGACAGAGACAGCTGGACAGAGCTCCTGAAAACATTTCAAAATACCCCCTCCCCCTGCCCTGCCCTGCCTTTGGGGTCCACCGGCACT CCAGTTGGATGGCACAACATAGTGTATCCGTGCAGAAGCCGAGCTGGCATTTTCACCAGTGTAGCCAAGGGCCTTTGCCAAGGGCAGAGC AGGTGGAGCCCTCTGCCTGCCCTATCACACATACGGGTACTTGCTTTTCACTGTGATGTTTAAGAGAATGTATGAACAGTTTACATTTTC CTTAGAAATACATTGATGGGATCACAGTTGGCTTTAAAAACCAACAACAATCAACCACCTGTAAGTCTTTGTCTTCACCTATTATCATCT GGAGGTAAATCTCTTTATATGATGATGCCAAAGGGCAAATTGCTTTTCAAATTCAGCAAGTTCTCAGCTTGTGTGACGGAAGGTCCTTCA GAGGACCTGAGGAATGCCTGGGAGAGGCTAAGCCTCAGGCTTCAATGCTTCTGGGGTTGGGCATGAGGATGTACACAGACACCCACTACC TTACTACTCACACTTCATTTCACTCCTTTTGTAAATTTCCAATTTAAAAATCAAGCACGTCTTTTTAGTGAGATAAAATCTGAGCTCTTC TGTAGAAAAATCAATCTCTACCAGTAGAAAATGCCAGGGCTTGATGGAAGAGCTGTGTAGCCCTTTCTATGCCAAAGCCAGGAAATTTGG GGGGCAGGAGGAGGTTCTCAGAATCCAGTCTGTATCTTTGCTGTATGCCAAACTGAAACCACTGGGAATAATTTATGAAACATAAAAATC |
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FusionGenePPI for EPS15_TTC39A |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| EPS15 | RNF11, SNAP91, AGFG1, NAGPA, STON2, HGS, AP2A2, DNM2, AP2A1, EGFR, CLINT1, EPN1, SCAMP1, STAM2, GRB2, CRK, RAB11FIP2, REPS2, UBE2D1, UBE2D2, UBE2D3, UBE2H, UBE2E1, SLC6A3, PARK2, USP8, CD4, EPS15, OCLN, UBQLN1, UBC, NEDD4, GJA1, TGFB1, FCHO2, ITSN1, ITSN2, ELAVL1, RAD23A, UBQLN2, EPN3, SH3BP4, AP1B1, NUMB, SPG20, TFAP2A, ABL1, AP2B1, IQGAP1, KRT85, KRT1, KRT10, KRT2, AP2M1, KRT14, KRT86, KRT5, KRT6A, KRT16, KRT9, HSPA8, KRT35, HSPA9, KRT17, KRT33B, KRT83, BMP2K, KRT34, KRT82, NONO, KRT38, KRT75, KRT79, PRDX1, KRT36, KRT32, MAP4, HSPA1L, HSPA1B, KRT37, HSPA5, KRT73, AP2S1, NECAP2, TRAF2, MCCC2, KRT4, ACTB, KRT3, VPRBP, TUBB, HIST4H4, PCCB, KRTAP9-3, NECAP1, VSIG8, CCT3, CRKL, FN1, VCAM1, LAPTM5, ITGA4, OPTN, RABL6, EPHA2, CORO7, AGFG2, SLC25A41, AURKA, SPC25, NTRK1, TMEM17, XPO1, CAPZA2, CLTB, CLTC, DBN1, FLNA, GAK, MYH9, PPP1CB, PICALM, PDLIM7, SYNPO, MAPRE1, LIMA1, GTSE1, ANLN, MYO19, MAPK14, AP1G1, MYO6, SPOPL, SGIP1, FCHO1, CDH1, RUNDC3A, LSR, STAMBPL1, CCDC172, OXCT1, MTNR1A, RNF26 | TTC39A | P2RY12 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | EPS15 | chr1:51912632 | chr1:51787497 | ENST00000371733 | - | 10 | 25 | 2_330 | 265 | 897 | DAB2 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for EPS15_TTC39A |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for EPS15_TTC39A |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | TTC39A | C0023903 | Liver neoplasms | 1 | CTD_human |
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