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Fusion gene ID: 11869 |
FusionGeneSummary for EPS15_TRABD2B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: EPS15_TRABD2B | Fusion gene ID: 11869 | Hgene | Tgene | Gene symbol | EPS15 | TRABD2B | Gene ID | 2060 | 388630 |
| Gene name | epidermal growth factor receptor pathway substrate 15 | TraB domain containing 2B | |
| Synonyms | AF-1P|AF1P|MLLT5 | TIKI2 | |
| Cytomap | 1p32.3 | 1p33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | epidermal growth factor receptor substrate 15ALL1 fused gene from chromosome 1protein AF-1p | metalloprotease TIKI2TRAB domain-containing protein 2BUPF0632 protein Aheart, kidney and adipose-enriched transmembrane protein homolog | |
| Modification date | 20180522 | 20180403 | |
| UniProtAcc | P42566 | A6NFA1 | |
| Ensembl transtripts involved in fusion gene | ENST00000371730, ENST00000371733, ENST00000396122, ENST00000493793, | ENST00000606738, ENST00000435576, | |
| Fusion gene scores | * DoF score | 10 X 7 X 8=560 | 4 X 2 X 4=32 |
| # samples | 10 | 4 | |
| ** MAII score | log2(10/560*10)=-2.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: EPS15 [Title/Abstract] AND TRABD2B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | EPS15 | GO:0048268 | clathrin coat assembly | 12807910 |
| Tgene | TRABD2B | GO:0006508 | proteolysis | 22726442 |
| Tgene | TRABD2B | GO:0030178 | negative regulation of Wnt signaling pathway | 22726442 |
| Tgene | TRABD2B | GO:0032461 | positive regulation of protein oligomerization | 22726442 |
| Tgene | TRABD2B | GO:1904808 | positive regulation of protein oxidation | 22726442 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | GBM | TCGA-16-1045-01B | EPS15 | chr1 | 51984871 | - | TRABD2B | chr1 | 48267291 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000371730 | ENST00000606738 | EPS15 | chr1 | 51984871 | - | TRABD2B | chr1 | 48267291 | - |
| 5CDS-5UTR | ENST00000371730 | ENST00000435576 | EPS15 | chr1 | 51984871 | - | TRABD2B | chr1 | 48267291 | - |
| In-frame | ENST00000371733 | ENST00000606738 | EPS15 | chr1 | 51984871 | - | TRABD2B | chr1 | 48267291 | - |
| 5CDS-5UTR | ENST00000371733 | ENST00000435576 | EPS15 | chr1 | 51984871 | - | TRABD2B | chr1 | 48267291 | - |
| intron-3CDS | ENST00000396122 | ENST00000606738 | EPS15 | chr1 | 51984871 | - | TRABD2B | chr1 | 48267291 | - |
| intron-5UTR | ENST00000396122 | ENST00000435576 | EPS15 | chr1 | 51984871 | - | TRABD2B | chr1 | 48267291 | - |
| intron-3CDS | ENST00000493793 | ENST00000606738 | EPS15 | chr1 | 51984871 | - | TRABD2B | chr1 | 48267291 | - |
| intron-5UTR | ENST00000493793 | ENST00000435576 | EPS15 | chr1 | 51984871 | - | TRABD2B | chr1 | 48267291 | - |
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FusionProtFeatures for EPS15_TRABD2B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| EPS15 | TRABD2B |
| Involved in cell growth regulation. May be involved inthe regulation of mitogenic signals and control of cellproliferation. Involved in the internalization of ligand-induciblereceptors of the receptor tyrosine kinase (RTK) type, inparticular EGFR. Plays a role in the assembly of clathrin-coatedpits (CCPs). Acts as a clathrin adapter required for post-Golgitrafficking. Seems to be involved in CCPs maturation includinginvagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1as DAB2-dependent cargo but not TFR seems to require associationwith DAB2. {ECO:0000269|PubMed:16903783,ECO:0000269|PubMed:18362181, ECO:0000269|PubMed:19458185,ECO:0000269|PubMed:22648170}. | Metalloprotease that acts as a negative regulator of theWnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage,Wnt proteins become oxidized and form large disulfide-bondoligomers, leading to their inactivation. Able to cleave WNT3A,WNT5, but not WNT11. Required for head formation.{ECO:0000269|PubMed:22726442}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >TRABD2B | chr1:51984871 | chr1:48267291 | ENST00000606738 | - | 1 | 7 | 516_517 | 222 | 518 | Topological domain | Cytoplasmic |
| Tgene | >TRABD2B | chr1:51984871 | chr1:48267291 | ENST00000606738 | - | 1 | 7 | 495_515 | 222 | 518 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 173_184 | 11 | 897 | Calcium binding | Note=1 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 236_247 | 11 | 897 | Calcium binding | Note=2 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 768_850 | 11 | 897 | Compositional bias | Note=Pro-rich |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 128_216 | 11 | 897 | Domain | EH 2 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 15_104 | 11 | 897 | Domain | EH 1 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 160_195 | 11 | 897 | Domain | EF-hand 1 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 223_258 | 11 | 897 | Domain | EF-hand 2 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 224_314 | 11 | 897 | Domain | EH 3 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 851_870 | 11 | 897 | Domain | UIM 1 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 877_896 | 11 | 897 | Domain | UIM 2 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 768_774 | 11 | 897 | Motif | Note=SH3-binding |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 599_827 | 11 | 897 | Region | Note=15 X 3 AA repeats of D-P-F |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 599_601 | 11 | 897 | Repeat | Note=1 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 623_625 | 11 | 897 | Repeat | Note=2 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 629_631 | 11 | 897 | Repeat | Note=3 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 634_636 | 11 | 897 | Repeat | Note=4 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 640_642 | 11 | 897 | Repeat | Note=5 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 645_647 | 11 | 897 | Repeat | Note=6 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 651_653 | 11 | 897 | Repeat | Note=7 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 664_666 | 11 | 897 | Repeat | Note=8 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 672_674 | 11 | 897 | Repeat | Note=9 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 692_694 | 11 | 897 | Repeat | Note=10 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 709_711 | 11 | 897 | Repeat | Note=11 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 737_739 | 11 | 897 | Repeat | Note=12 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 798_800 | 11 | 897 | Repeat | Note=13 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 804_806 | 11 | 897 | Repeat | Note=14 |
| Hgene | >EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 825_827 | 11 | 897 | Repeat | Note=15 |
| Tgene | TRABD2B | chr1:51984871 | chr1:48267291 | ENST00000606738 | - | 1 | 7 | 20_494 | 222 | 518 | Topological domain | Extracellular |
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FusionGeneSequence for EPS15_TRABD2B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_EPS15_ENST00000371730_chr1_51984871_-_TRABD2B_ENST00000606738_chr1_48267291_-_307aa MAAAAQLSLTQVLFALNQTLLQQESVRAGSLQASYTTEDLIKHYNCGDLSAVIFNHDTSQLPNFINTTLPPHEQVTAQEIDSYFRQELIY KRNERMGKRVMALLRENEDKICFFAFGAGHFLGNNTVIDILRQAGLEVDHTPAGQAIHSPAPQSPAPSPEGTSTSPAPVTPAAAVPEAPS VTPTAPPEDEDPALSPHLLLPDSLSQLEEFGRQRKWHKRQSTHQRPRQFNDLWVRIEDSTTASPPPLPLQPTHSSGTAKPPFQLSDQLQQ >In-frame_EPS15_ENST00000371733_chr1_51984871_-_TRABD2B_ENST00000606738_chr1_48267291_-_307aa MAAAAQLSLTQVLFALNQTLLQQESVRAGSLQASYTTEDLIKHYNCGDLSAVIFNHDTSQLPNFINTTLPPHEQVTAQEIDSYFRQELIY KRNERMGKRVMALLRENEDKICFFAFGAGHFLGNNTVIDILRQAGLEVDHTPAGQAIHSPAPQSPAPSPEGTSTSPAPVTPAAAVPEAPS VTPTAPPEDEDPALSPHLLLPDSLSQLEEFGRQRKWHKRQSTHQRPRQFNDLWVRIEDSTTASPPPLPLQPTHSSGTAKPPFQLSDQLQQ |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_EPS15_ENST00000371730_chr1_51984871_-_TRABD2B_ENST00000606738_chr1_48267291_-_921nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGGTGCTGTTTGCCCTGAACCAAACCCTGCTGCAGCAGGAGAGTGTGCGGGCCGGGAGC CTGCAGGCCTCCTACACCACGGAGGACCTCATCAAGCACTACAACTGCGGAGACCTCAGCGCAGTCATCTTCAACCACGACACATCCCAG CTGCCCAACTTTATCAACACCACCCTCCCGCCACACGAGCAGGTGACGGCCCAGGAGATTGACAGCTACTTCCGCCAGGAGCTCATCTAC AAGAGGAATGAGCGCATGGGGAAGAGGGTCATGGCGCTTCTACGGGAGAACGAGGACAAGATCTGCTTCTTTGCCTTCGGAGCAGGTCAC TTTCTGGGGAACAACACAGTCATCGACATCCTGCGGCAGGCAGGGCTGGAGGTGGACCACACACCCGCCGGGCAGGCCATACACAGCCCT GCCCCCCAGAGCCCAGCGCCCTCTCCTGAGGGGACCTCGACGAGCCCGGCCCCAGTGACCCCAGCTGCCGCTGTCCCCGAAGCACCCTCT GTGACCCCCACCGCCCCACCAGAGGATGAGGATCCAGCCCTGTCCCCACACCTCCTGCTCCCCGACAGCCTCAGCCAGCTGGAGGAGTTT GGCCGGCAGAGGAAGTGGCACAAGAGGCAGAGCACACACCAGCGGCCGCGGCAGTTCAATGACCTCTGGGTCCGCATCGAGGACAGCACC ACCGCCTCACCACCCCCGCTGCCCCTGCAGCCCACCCACAGCTCGGGGACCGCCAAGCCCCCCTTCCAGCTTTCAGACCAGCTACAACAG CAGGACCCGCCAGGGCCCGCCAGCAGCTCGGCACCCACCCTGGGCCTTCTCCCCGCCATCGCCACCACCATCGCTGTCTGCTTCCTGCTG >In-frame_EPS15_ENST00000371733_chr1_51984871_-_TRABD2B_ENST00000606738_chr1_48267291_-_921nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGGTGCTGTTTGCCCTGAACCAAACCCTGCTGCAGCAGGAGAGTGTGCGGGCCGGGAGC CTGCAGGCCTCCTACACCACGGAGGACCTCATCAAGCACTACAACTGCGGAGACCTCAGCGCAGTCATCTTCAACCACGACACATCCCAG CTGCCCAACTTTATCAACACCACCCTCCCGCCACACGAGCAGGTGACGGCCCAGGAGATTGACAGCTACTTCCGCCAGGAGCTCATCTAC AAGAGGAATGAGCGCATGGGGAAGAGGGTCATGGCGCTTCTACGGGAGAACGAGGACAAGATCTGCTTCTTTGCCTTCGGAGCAGGTCAC TTTCTGGGGAACAACACAGTCATCGACATCCTGCGGCAGGCAGGGCTGGAGGTGGACCACACACCCGCCGGGCAGGCCATACACAGCCCT GCCCCCCAGAGCCCAGCGCCCTCTCCTGAGGGGACCTCGACGAGCCCGGCCCCAGTGACCCCAGCTGCCGCTGTCCCCGAAGCACCCTCT GTGACCCCCACCGCCCCACCAGAGGATGAGGATCCAGCCCTGTCCCCACACCTCCTGCTCCCCGACAGCCTCAGCCAGCTGGAGGAGTTT GGCCGGCAGAGGAAGTGGCACAAGAGGCAGAGCACACACCAGCGGCCGCGGCAGTTCAATGACCTCTGGGTCCGCATCGAGGACAGCACC ACCGCCTCACCACCCCCGCTGCCCCTGCAGCCCACCCACAGCTCGGGGACCGCCAAGCCCCCCTTCCAGCTTTCAGACCAGCTACAACAG CAGGACCCGCCAGGGCCCGCCAGCAGCTCGGCACCCACCCTGGGCCTTCTCCCCGCCATCGCCACCACCATCGCTGTCTGCTTCCTGCTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_EPS15_ENST00000371730_chr1_51984871_-_TRABD2B_ENST00000606738_chr1_48267291_-_6305nt TGGAAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGGTGCTGTTTGCCCTGAACCAAACCCTGCTGCAGCAGGAGAGTGTGCG GGCCGGGAGCCTGCAGGCCTCCTACACCACGGAGGACCTCATCAAGCACTACAACTGCGGAGACCTCAGCGCAGTCATCTTCAACCACGA CACATCCCAGCTGCCCAACTTTATCAACACCACCCTCCCGCCACACGAGCAGGTGACGGCCCAGGAGATTGACAGCTACTTCCGCCAGGA GCTCATCTACAAGAGGAATGAGCGCATGGGGAAGAGGGTCATGGCGCTTCTACGGGAGAACGAGGACAAGATCTGCTTCTTTGCCTTCGG AGCAGGTCACTTTCTGGGGAACAACACAGTCATCGACATCCTGCGGCAGGCAGGGCTGGAGGTGGACCACACACCCGCCGGGCAGGCCAT ACACAGCCCTGCCCCCCAGAGCCCAGCGCCCTCTCCTGAGGGGACCTCGACGAGCCCGGCCCCAGTGACCCCAGCTGCCGCTGTCCCCGA AGCACCCTCTGTGACCCCCACCGCCCCACCAGAGGATGAGGATCCAGCCCTGTCCCCACACCTCCTGCTCCCCGACAGCCTCAGCCAGCT GGAGGAGTTTGGCCGGCAGAGGAAGTGGCACAAGAGGCAGAGCACACACCAGCGGCCGCGGCAGTTCAATGACCTCTGGGTCCGCATCGA GGACAGCACCACCGCCTCACCACCCCCGCTGCCCCTGCAGCCCACCCACAGCTCGGGGACCGCCAAGCCCCCCTTCCAGCTTTCAGACCA GCTACAACAGCAGGACCCGCCAGGGCCCGCCAGCAGCTCGGCACCCACCCTGGGCCTTCTCCCCGCCATCGCCACCACCATCGCTGTCTG CTTCCTGCTGCATAGCCTTGGGCCCTCCTGACCTCGGCCACCCCAAGTGGAGAAGCCAGAGAAATGACACAGGGGTCTTCGGCCACACCC AACTGCTCCTGCCACCACCTCCAGGGGGTGCCCAACACGTCGAGGGCAGTCCACATGGGATTGGCTAGACACTCTAGAGCTTTACTGTAC CCAAGTTACATCTTCTTTTTTGTAGAAGGATCTTAATTTCCCATAGTGCTATGGGGCTCTTTTGTAAAATACGTGTCCATATTAAAAAAG AAAAATGTATTTATTCTACCGATAAAACTATTCTTATGTGGCCTGTGTTATAACCCCCTAGCCCTAGTGCTGGCCCGGGAGGGGAACCCG GGACATCAGTGACCTCCTGTGGACTGTGGCTCTGGACTGGCTTGCTCTTGGATCACCGAAGCCTCCTGGGTCTGGGTTTGGCTTCTCCGA CTGTGGGGCCCTCAGCAGGAGGGGCAGGCAGGCAGGCTTAGCCTTTGTGAAGCTGGATTTGGGAGCCAGAGGTGTGAACGTTGGCCATCC TCCCCTCTGCTGGATGCACCCGCGGCCTGGGAAGATAATTTAGGAAAGAGAATGCTGCTATTGTGAAACCCCTGAGTGTCTATCTGGCCC TCCAGAGCTCTTGGTAAGTGTTTTCAACCAAAGCGCTGGGGTGGGGTGGGAGGTGGGATACTGGTGCTGAGGAAAGCAGTCCCCACCCCA CAGAACAAATGAATAAACTGAGATCCAGAGAGAACCAGGTGGGTAGCCCAAGGTCACACGGCAAGTGGGAGAGTGAGGACATAAATCCAG ACCTCTCTGTTCTGGTGTCATGAATCCAGCTTGGGTTAAAGGAGAGGCTGTTGAAGTCCTGGCTAAATGGATTGAGCTGGGCCGAGGGAC TGGAGTGGGCACAGGAGGGCAGTTTTAGAGACAGGGGCTTAGGCCTCACATGATGTTAATAGTAATGAGAGCTGCCATTTTTCCAAAGCC TGCAGCGTGGCAAGCACTTTGCACACTTGCTTCACTGATTCTTGCGCTAGTTCTGTGAGATGTGACTATCCCCATTTCACAGATGAGGAA ACTGAGCCCCCCAAAGAGGCGAAGGGACTTGCTGAAGATCCCCCAGCCAGGATGTGGCCCCAGATCAGTGTGATGCAAAACAATTCCTGC CTCCTGTTCCCTGTTCTGCCACGTTCTCTCTGCAAGGGAGCAGATCTCACCCAAACTGGGGCCAGCACAAGCTTTCACTCCACCAAGAAA CCTTTTGGCCGGCTGCTTATGTTGACCCCTCTGGCCAAAGGGCTCTGGCAACTGCATGTGCCATGTGTCGCATGTCCTGACTTGCCAGAT CTTGGAGCCCACGAGAAGCTTTCCTGCCAAATCAAAGGCTGAGAGGTGGGCACAGCTGTGGGGCACCTGGGGAGGCACAGCAGCCAAGTG GGGAGGCAGGTGACAGGGACTCCGAGAGACTTTAGCCCCTCGGCTCCTCAAGGTGGTGGTTGAGGAGACAGAGGACCCAGGTGGGCTAAC TCCCACCTGGGAGGCCTGAAACCCTATGGGGCAGGTGCCTCAGTAATTACAGAGTCCTGGAACCTGACAGCAGAAAGGACCCTTCACTTG ATGGATAATAGTAACAGTAGGAGGAATAATAAGGCCCACAGAGAGGAGACACTTCTCCAAGGCTGCACAGCCGGGTGGGCCTGCTGACTC CCAGCCCAGTGCACCCCAACTTTATAGCTTCGTGGGTTTCCCTGGCAGGCTTGATGGCAGCTAATTGGCCCCAGTGCCATCTTGCCCAGC TTGGCAGCTATCTCCCTTCTGAGACGGCAAGTTCTGGGCAGCTCATGGGATGGTCAGGAGTCCCACGGGCATCTTGGCAGGCAGCTGAAT TCTTTACAGCTCAGCCCTGATGGACGTGTTTGAGCTTGAGACCTGGCAGGAGACTGGAGCTCTGCCTTAGAGGGCCCAGCCAGCCCTGTG GGCACCATGCTCTAAACTGAACTTGACCTCAATCCAGGCTGGAGTTGGTTTATCCTTGGCAAAAATGTGACTTCCTATTTCTGAGCGGGA AGGGGCTTAGCTGACTTATAAAGCAGGCTCAGAAGTTGGACATCAAACGGATCGTGCAGTGCACTATTTGGATGAGATAAGTGTAAAGGA ATTAGAAGCACACAGGCCAGATTCCTCTCTGTTTGGGGCAGAGTATGGCGTGAGACGTATTGAGATGGAGCTTGAGGTTAATTAAAGATG AAGCATTTGGGTAAACAGTCCAGGCACCTGACCGTGTGCCCAGATCTGTGCCAGGCACTGAGCCAAGAAGGTAAATTAATGCAGCTTGTA ATTACTGAGCACATGCAATGCCAGGCTCTGTATTAGAGCTGAATCTAACCACTCTCCTTGGCCCAGAGGAACTCATTATCAAGATGGGAC AAGCAGTGCAATGCTAGATTACGTCGTCCTGGCCCCTAACTTCAGGAAGATTCAGCCTTAGTCTTTCCCAGATCCCTCCTCTGGGCATAT TAGGGGATCCTAAACTCTCCCTTACCCTAATTCAAGTGTTTAAAGAAAGATGGCTAGACTAACCGATGGAGTAGACATGTACCTACAGGA GAGCAAGAGCCAATGTGGTCAGACATCTGTTGCCAAAGTTCACTGATCTCTGAGGACCACCAGCTGGCCAGGGTCTGAAATGAACTCAAC TTGCTGACTTATGACCCAAAAGACTTGAGGCACATATGCAGGAATCTGCATGTCTGGGGCACTTGAATTCTCTCATCCTGGGCCAGAGAA CCACCATTCCATAAGCAGCAACCCACACCTTTGACACGATCTATCCACCACTAACTGACATTTCTTCCAGAAACGTTCTTTGTGCCCAGC CTCATAAAATGCTCCTGTTGCTCTGAGAAATTTGTGTGCACTTCTTAGACTTTTCTGTTTGACTGTGAGGCAGGCAGGAAAGATGAAAGG TCTGAGACCCAGCAGGTAAAGTGATCTGCTTAAGGTCGGGCAGCATGTTATTGTGGCCCTGGGTCCTCTACCTCTCACGAAAGCTGACTG TGTGATGAAGGGCTCTCTGGGGCATGTTGGAATGGCCATGTCCCCAGGTCTTCCTCCAGTGGTGGGTCTGATGCACCAGCAGCCAGATGA AGACAGGGAGAGCCCTGTCATCCACAGTGGAGGGAGAAGAATCAGGCTGCCAGGGAGCTGCAAAGGGCTGCTGAGGATGCCTCCAGTCCT GAGAGTCAAAGATCTGGGATCTAGGAAGCATGGAACCTTGTGCTGGTTATGAACAAATTTGTCCTTGCATTGAAAGACCCTAAGCATATT TTCTTCATGCTAAATAATGTGTTATCTACAACTTCCTGGCCTCGGCTAGACCTGGACAAGCCTAGGTGCTCAGGCCCCTTGTCCCACTTG CCTAATCTCCAGCCCAGGGCCATTGTCACAGTGGATCCCAAAGAGGAGGGAAAGTCCTTCTACCAAAAGGAAAGTCTATTGAAAATGCTG TGAAGGACAAGAGAAGTTCTCCAGGGAATTGCAGCTTTGATGGCATCCTGTGTGGCAGACAGCAGAATTGGGGCTGGTGATAGTTTTTCA GTGACTGTGAGATAAGAACCAGAGTCCTCAGCCTCACCCTGAAGTGTCCGCTAGACCCTTCGTGACCCAACCCTGCTGACCAGCCACGTC TCTCATGTCTCTTACCCTGTGCCTGGCCAGCGTGATGTGCAGTCATCTCTAGAATAGACAGGATGTTTCACACATGCTGCTCCCTACCCC TGGAAACTCCCTTCTCTCCCCTGTAACTGCTCATCCATTGAGGATCAACACAGATAGCACTTCCTCCAGGAAGCCCCCTCCCATTCCTTT GTGCTTTCTTAGCATCTATCACAATACCCACTGCCCAGTGTTGTGACTATCTAGTGTGTATCTGCTCCTCTCGGACTGTGAGCAGCTTAA TGGCAGGGGTCATGTAAATTTGTTTTTGTACCCTCATCTGACACAAAGGTGGTGCTCAACAGATGTGTAGAGAGAGAAAGGAAGGGAAGG AAGCTGAAGGAAGGGGAGGAAGAAAGGAATGAAGGCAGAAAAGAAGGAGAGAGGCAGACCTTAGTTCCACCAGTGGCATAATTTCCACCA AGCCAAAGCTGTCTGGGGATGGCCCGGAGCCCCCAAGGGTGGCAGGTTTCCCATCGGGAGAGGTGTTTGAGCAGGGGCAGTGTGCCCACT GGCTGAAGAAGTGGTAGGAGAGTTGACATCTTGCCAAGGGCCTGGTGTAGATGACATTGAGGGTCCCTCCTGGCTCTGCAATGATCAAGT TCTATGAACATTGTTATTTTTCCAGAAATTCATCTGAGCAGCCAAAAAAAATCACCCCGCTGGCTGTCTAAACCAGTAAGGTTCAGGAAT AAGTCCAGCCTCCCCACTCCACCCACAACCACCACCACCCCTCACAGCGCCCCCTTCAATGACCCAGCTGGGCTTGACTGCTGCCTTTGG GTGGGGGAACTTCTGAAAGGTGGAGGAGGAGTGAACTGGAACCCAGGCCTGCAGCCCAGCCCAGAGCTCCTTCCCGCTCTGCCCCACTCC CTGACCCCAGGGGAGGAAAGGGTTCACGAGAACTGATTGACCCCCTACTTGGCTCTTTCCAGGGAGCATCGGCTATCCTCACCCTTTCTC CAAGTGGGAGCTGGGCTCTTCCTTTCCGGAGATACTCTGGATACTCCTTCACTTTGCTGGATGACCTTGGGCAAGTTCCTGTCCCTCTCT GAGCCTTCACTTCCTCATCTGTCAAATGAAGACCTTGATTCCTGCCTGGGCAGTTCTAGGGCTGGAGGGCAGGGGTGACATGGACAATCT TGGGCCTCCATGGAGATGAGGTGCTTGGCTTTCTTCCCAGGACCCACAGGCTGCCATGGGATTGAAAGCATGTGGAGGTGGGAAAGGTGA CAGAGTAGCATGCCTCCAAGGCCCCCTTCATCCCAGTCCTGCTGTGGGGAAAGTGGGCTTTGAACGGGATCCAAGTCTAAGATGTTTCCG GTGAGCTGCCAGGGACAAAGGGCTCTCAGACATCTTGGGTCCCCAGTGGCTGGGGTGGGCAGGGGCTGATTCAGCCAAAGGAGGCTCTAG CCCAGAACAGAGGAAGCCAGAGCCCCTGCCCCATTCTTGAGCCTCACAGAGCTTGTCCCCGAGTTGATTCACTGTGCAACACAGGCTTCA GATTCATGTATTTGAAAGGTATTCATGATGTTGTTCTCTTATCACCTCTGCCCCTCACCTCTGTGAATTATCATGAAGAGTCCTTTAAGA GTATAAATAGAAGACAAAGAAAGATGCTATTAATGTTATTTTGCCAAAAATATTTTTGTAGCATAATATATTAATAAAAGATATTATGAA >In-frame_EPS15_ENST00000371733_chr1_51984871_-_TRABD2B_ENST00000606738_chr1_48267291_-_6392nt GCCCCGGCCTCGCCTGCGGCCGCTCCCTCCGCCTCCTCCCCGCCCCGAGCCCCAGTCAGCCCGTCTTCCTTCCCCTCCCTTGCATGATGG AAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGGTGCTGTTTGCCCTGAACCAAACCCTGCTGCAGCAGGAGAGTGTGCGGGC CGGGAGCCTGCAGGCCTCCTACACCACGGAGGACCTCATCAAGCACTACAACTGCGGAGACCTCAGCGCAGTCATCTTCAACCACGACAC ATCCCAGCTGCCCAACTTTATCAACACCACCCTCCCGCCACACGAGCAGGTGACGGCCCAGGAGATTGACAGCTACTTCCGCCAGGAGCT CATCTACAAGAGGAATGAGCGCATGGGGAAGAGGGTCATGGCGCTTCTACGGGAGAACGAGGACAAGATCTGCTTCTTTGCCTTCGGAGC AGGTCACTTTCTGGGGAACAACACAGTCATCGACATCCTGCGGCAGGCAGGGCTGGAGGTGGACCACACACCCGCCGGGCAGGCCATACA CAGCCCTGCCCCCCAGAGCCCAGCGCCCTCTCCTGAGGGGACCTCGACGAGCCCGGCCCCAGTGACCCCAGCTGCCGCTGTCCCCGAAGC ACCCTCTGTGACCCCCACCGCCCCACCAGAGGATGAGGATCCAGCCCTGTCCCCACACCTCCTGCTCCCCGACAGCCTCAGCCAGCTGGA GGAGTTTGGCCGGCAGAGGAAGTGGCACAAGAGGCAGAGCACACACCAGCGGCCGCGGCAGTTCAATGACCTCTGGGTCCGCATCGAGGA CAGCACCACCGCCTCACCACCCCCGCTGCCCCTGCAGCCCACCCACAGCTCGGGGACCGCCAAGCCCCCCTTCCAGCTTTCAGACCAGCT ACAACAGCAGGACCCGCCAGGGCCCGCCAGCAGCTCGGCACCCACCCTGGGCCTTCTCCCCGCCATCGCCACCACCATCGCTGTCTGCTT CCTGCTGCATAGCCTTGGGCCCTCCTGACCTCGGCCACCCCAAGTGGAGAAGCCAGAGAAATGACACAGGGGTCTTCGGCCACACCCAAC TGCTCCTGCCACCACCTCCAGGGGGTGCCCAACACGTCGAGGGCAGTCCACATGGGATTGGCTAGACACTCTAGAGCTTTACTGTACCCA AGTTACATCTTCTTTTTTGTAGAAGGATCTTAATTTCCCATAGTGCTATGGGGCTCTTTTGTAAAATACGTGTCCATATTAAAAAAGAAA AATGTATTTATTCTACCGATAAAACTATTCTTATGTGGCCTGTGTTATAACCCCCTAGCCCTAGTGCTGGCCCGGGAGGGGAACCCGGGA CATCAGTGACCTCCTGTGGACTGTGGCTCTGGACTGGCTTGCTCTTGGATCACCGAAGCCTCCTGGGTCTGGGTTTGGCTTCTCCGACTG TGGGGCCCTCAGCAGGAGGGGCAGGCAGGCAGGCTTAGCCTTTGTGAAGCTGGATTTGGGAGCCAGAGGTGTGAACGTTGGCCATCCTCC CCTCTGCTGGATGCACCCGCGGCCTGGGAAGATAATTTAGGAAAGAGAATGCTGCTATTGTGAAACCCCTGAGTGTCTATCTGGCCCTCC AGAGCTCTTGGTAAGTGTTTTCAACCAAAGCGCTGGGGTGGGGTGGGAGGTGGGATACTGGTGCTGAGGAAAGCAGTCCCCACCCCACAG AACAAATGAATAAACTGAGATCCAGAGAGAACCAGGTGGGTAGCCCAAGGTCACACGGCAAGTGGGAGAGTGAGGACATAAATCCAGACC TCTCTGTTCTGGTGTCATGAATCCAGCTTGGGTTAAAGGAGAGGCTGTTGAAGTCCTGGCTAAATGGATTGAGCTGGGCCGAGGGACTGG AGTGGGCACAGGAGGGCAGTTTTAGAGACAGGGGCTTAGGCCTCACATGATGTTAATAGTAATGAGAGCTGCCATTTTTCCAAAGCCTGC AGCGTGGCAAGCACTTTGCACACTTGCTTCACTGATTCTTGCGCTAGTTCTGTGAGATGTGACTATCCCCATTTCACAGATGAGGAAACT GAGCCCCCCAAAGAGGCGAAGGGACTTGCTGAAGATCCCCCAGCCAGGATGTGGCCCCAGATCAGTGTGATGCAAAACAATTCCTGCCTC CTGTTCCCTGTTCTGCCACGTTCTCTCTGCAAGGGAGCAGATCTCACCCAAACTGGGGCCAGCACAAGCTTTCACTCCACCAAGAAACCT TTTGGCCGGCTGCTTATGTTGACCCCTCTGGCCAAAGGGCTCTGGCAACTGCATGTGCCATGTGTCGCATGTCCTGACTTGCCAGATCTT GGAGCCCACGAGAAGCTTTCCTGCCAAATCAAAGGCTGAGAGGTGGGCACAGCTGTGGGGCACCTGGGGAGGCACAGCAGCCAAGTGGGG AGGCAGGTGACAGGGACTCCGAGAGACTTTAGCCCCTCGGCTCCTCAAGGTGGTGGTTGAGGAGACAGAGGACCCAGGTGGGCTAACTCC CACCTGGGAGGCCTGAAACCCTATGGGGCAGGTGCCTCAGTAATTACAGAGTCCTGGAACCTGACAGCAGAAAGGACCCTTCACTTGATG GATAATAGTAACAGTAGGAGGAATAATAAGGCCCACAGAGAGGAGACACTTCTCCAAGGCTGCACAGCCGGGTGGGCCTGCTGACTCCCA GCCCAGTGCACCCCAACTTTATAGCTTCGTGGGTTTCCCTGGCAGGCTTGATGGCAGCTAATTGGCCCCAGTGCCATCTTGCCCAGCTTG GCAGCTATCTCCCTTCTGAGACGGCAAGTTCTGGGCAGCTCATGGGATGGTCAGGAGTCCCACGGGCATCTTGGCAGGCAGCTGAATTCT TTACAGCTCAGCCCTGATGGACGTGTTTGAGCTTGAGACCTGGCAGGAGACTGGAGCTCTGCCTTAGAGGGCCCAGCCAGCCCTGTGGGC ACCATGCTCTAAACTGAACTTGACCTCAATCCAGGCTGGAGTTGGTTTATCCTTGGCAAAAATGTGACTTCCTATTTCTGAGCGGGAAGG GGCTTAGCTGACTTATAAAGCAGGCTCAGAAGTTGGACATCAAACGGATCGTGCAGTGCACTATTTGGATGAGATAAGTGTAAAGGAATT AGAAGCACACAGGCCAGATTCCTCTCTGTTTGGGGCAGAGTATGGCGTGAGACGTATTGAGATGGAGCTTGAGGTTAATTAAAGATGAAG CATTTGGGTAAACAGTCCAGGCACCTGACCGTGTGCCCAGATCTGTGCCAGGCACTGAGCCAAGAAGGTAAATTAATGCAGCTTGTAATT ACTGAGCACATGCAATGCCAGGCTCTGTATTAGAGCTGAATCTAACCACTCTCCTTGGCCCAGAGGAACTCATTATCAAGATGGGACAAG CAGTGCAATGCTAGATTACGTCGTCCTGGCCCCTAACTTCAGGAAGATTCAGCCTTAGTCTTTCCCAGATCCCTCCTCTGGGCATATTAG GGGATCCTAAACTCTCCCTTACCCTAATTCAAGTGTTTAAAGAAAGATGGCTAGACTAACCGATGGAGTAGACATGTACCTACAGGAGAG CAAGAGCCAATGTGGTCAGACATCTGTTGCCAAAGTTCACTGATCTCTGAGGACCACCAGCTGGCCAGGGTCTGAAATGAACTCAACTTG CTGACTTATGACCCAAAAGACTTGAGGCACATATGCAGGAATCTGCATGTCTGGGGCACTTGAATTCTCTCATCCTGGGCCAGAGAACCA CCATTCCATAAGCAGCAACCCACACCTTTGACACGATCTATCCACCACTAACTGACATTTCTTCCAGAAACGTTCTTTGTGCCCAGCCTC ATAAAATGCTCCTGTTGCTCTGAGAAATTTGTGTGCACTTCTTAGACTTTTCTGTTTGACTGTGAGGCAGGCAGGAAAGATGAAAGGTCT GAGACCCAGCAGGTAAAGTGATCTGCTTAAGGTCGGGCAGCATGTTATTGTGGCCCTGGGTCCTCTACCTCTCACGAAAGCTGACTGTGT GATGAAGGGCTCTCTGGGGCATGTTGGAATGGCCATGTCCCCAGGTCTTCCTCCAGTGGTGGGTCTGATGCACCAGCAGCCAGATGAAGA CAGGGAGAGCCCTGTCATCCACAGTGGAGGGAGAAGAATCAGGCTGCCAGGGAGCTGCAAAGGGCTGCTGAGGATGCCTCCAGTCCTGAG AGTCAAAGATCTGGGATCTAGGAAGCATGGAACCTTGTGCTGGTTATGAACAAATTTGTCCTTGCATTGAAAGACCCTAAGCATATTTTC TTCATGCTAAATAATGTGTTATCTACAACTTCCTGGCCTCGGCTAGACCTGGACAAGCCTAGGTGCTCAGGCCCCTTGTCCCACTTGCCT AATCTCCAGCCCAGGGCCATTGTCACAGTGGATCCCAAAGAGGAGGGAAAGTCCTTCTACCAAAAGGAAAGTCTATTGAAAATGCTGTGA AGGACAAGAGAAGTTCTCCAGGGAATTGCAGCTTTGATGGCATCCTGTGTGGCAGACAGCAGAATTGGGGCTGGTGATAGTTTTTCAGTG ACTGTGAGATAAGAACCAGAGTCCTCAGCCTCACCCTGAAGTGTCCGCTAGACCCTTCGTGACCCAACCCTGCTGACCAGCCACGTCTCT CATGTCTCTTACCCTGTGCCTGGCCAGCGTGATGTGCAGTCATCTCTAGAATAGACAGGATGTTTCACACATGCTGCTCCCTACCCCTGG AAACTCCCTTCTCTCCCCTGTAACTGCTCATCCATTGAGGATCAACACAGATAGCACTTCCTCCAGGAAGCCCCCTCCCATTCCTTTGTG CTTTCTTAGCATCTATCACAATACCCACTGCCCAGTGTTGTGACTATCTAGTGTGTATCTGCTCCTCTCGGACTGTGAGCAGCTTAATGG CAGGGGTCATGTAAATTTGTTTTTGTACCCTCATCTGACACAAAGGTGGTGCTCAACAGATGTGTAGAGAGAGAAAGGAAGGGAAGGAAG CTGAAGGAAGGGGAGGAAGAAAGGAATGAAGGCAGAAAAGAAGGAGAGAGGCAGACCTTAGTTCCACCAGTGGCATAATTTCCACCAAGC CAAAGCTGTCTGGGGATGGCCCGGAGCCCCCAAGGGTGGCAGGTTTCCCATCGGGAGAGGTGTTTGAGCAGGGGCAGTGTGCCCACTGGC TGAAGAAGTGGTAGGAGAGTTGACATCTTGCCAAGGGCCTGGTGTAGATGACATTGAGGGTCCCTCCTGGCTCTGCAATGATCAAGTTCT ATGAACATTGTTATTTTTCCAGAAATTCATCTGAGCAGCCAAAAAAAATCACCCCGCTGGCTGTCTAAACCAGTAAGGTTCAGGAATAAG TCCAGCCTCCCCACTCCACCCACAACCACCACCACCCCTCACAGCGCCCCCTTCAATGACCCAGCTGGGCTTGACTGCTGCCTTTGGGTG GGGGAACTTCTGAAAGGTGGAGGAGGAGTGAACTGGAACCCAGGCCTGCAGCCCAGCCCAGAGCTCCTTCCCGCTCTGCCCCACTCCCTG ACCCCAGGGGAGGAAAGGGTTCACGAGAACTGATTGACCCCCTACTTGGCTCTTTCCAGGGAGCATCGGCTATCCTCACCCTTTCTCCAA GTGGGAGCTGGGCTCTTCCTTTCCGGAGATACTCTGGATACTCCTTCACTTTGCTGGATGACCTTGGGCAAGTTCCTGTCCCTCTCTGAG CCTTCACTTCCTCATCTGTCAAATGAAGACCTTGATTCCTGCCTGGGCAGTTCTAGGGCTGGAGGGCAGGGGTGACATGGACAATCTTGG GCCTCCATGGAGATGAGGTGCTTGGCTTTCTTCCCAGGACCCACAGGCTGCCATGGGATTGAAAGCATGTGGAGGTGGGAAAGGTGACAG AGTAGCATGCCTCCAAGGCCCCCTTCATCCCAGTCCTGCTGTGGGGAAAGTGGGCTTTGAACGGGATCCAAGTCTAAGATGTTTCCGGTG AGCTGCCAGGGACAAAGGGCTCTCAGACATCTTGGGTCCCCAGTGGCTGGGGTGGGCAGGGGCTGATTCAGCCAAAGGAGGCTCTAGCCC AGAACAGAGGAAGCCAGAGCCCCTGCCCCATTCTTGAGCCTCACAGAGCTTGTCCCCGAGTTGATTCACTGTGCAACACAGGCTTCAGAT TCATGTATTTGAAAGGTATTCATGATGTTGTTCTCTTATCACCTCTGCCCCTCACCTCTGTGAATTATCATGAAGAGTCCTTTAAGAGTA TAAATAGAAGACAAAGAAAGATGCTATTAATGTTATTTTGCCAAAAATATTTTTGTAGCATAATATATTAATAAAAGATATTATGAATTC |
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FusionGenePPI for EPS15_TRABD2B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| EPS15 | RNF11, SNAP91, AGFG1, NAGPA, STON2, HGS, AP2A2, DNM2, AP2A1, EGFR, CLINT1, EPN1, SCAMP1, STAM2, GRB2, CRK, RAB11FIP2, REPS2, UBE2D1, UBE2D2, UBE2D3, UBE2H, UBE2E1, SLC6A3, PARK2, USP8, CD4, EPS15, OCLN, UBQLN1, UBC, NEDD4, GJA1, TGFB1, FCHO2, ITSN1, ITSN2, ELAVL1, RAD23A, UBQLN2, EPN3, SH3BP4, AP1B1, NUMB, SPG20, TFAP2A, ABL1, AP2B1, IQGAP1, KRT85, KRT1, KRT10, KRT2, AP2M1, KRT14, KRT86, KRT5, KRT6A, KRT16, KRT9, HSPA8, KRT35, HSPA9, KRT17, KRT33B, KRT83, BMP2K, KRT34, KRT82, NONO, KRT38, KRT75, KRT79, PRDX1, KRT36, KRT32, MAP4, HSPA1L, HSPA1B, KRT37, HSPA5, KRT73, AP2S1, NECAP2, TRAF2, MCCC2, KRT4, ACTB, KRT3, VPRBP, TUBB, HIST4H4, PCCB, KRTAP9-3, NECAP1, VSIG8, CCT3, CRKL, FN1, VCAM1, LAPTM5, ITGA4, OPTN, RABL6, EPHA2, CORO7, AGFG2, SLC25A41, AURKA, SPC25, NTRK1, TMEM17, XPO1, CAPZA2, CLTB, CLTC, DBN1, FLNA, GAK, MYH9, PPP1CB, PICALM, PDLIM7, SYNPO, MAPRE1, LIMA1, GTSE1, ANLN, MYO19, MAPK14, AP1G1, MYO6, SPOPL, SGIP1, FCHO1, CDH1, RUNDC3A, LSR, STAMBPL1, CCDC172, OXCT1, MTNR1A, RNF26 | TRABD2B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | EPS15 | chr1:51984871 | chr1:48267291 | ENST00000371733 | - | 1 | 25 | 2_330 | 11 | 897 | DAB2 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for EPS15_TRABD2B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for EPS15_TRABD2B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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