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Fusion gene ID: 11864 |
FusionGeneSummary for EPS15_CCDC18 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: EPS15_CCDC18 | Fusion gene ID: 11864 | Hgene | Tgene | Gene symbol | EPS15 | CCDC18 | Gene ID | 2060 | 343099 |
| Gene name | epidermal growth factor receptor pathway substrate 15 | coiled-coil domain containing 18 | |
| Synonyms | AF-1P|AF1P|MLLT5 | NY-SAR-41 | |
| Cytomap | 1p32.3 | 1p22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | epidermal growth factor receptor substrate 15ALL1 fused gene from chromosome 1protein AF-1p | coiled-coil domain-containing protein 18sarcoma antigen NY-SAR-24sarcoma antigen NY-SAR-41 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | P42566 | Q5T9S5 | |
| Ensembl transtripts involved in fusion gene | ENST00000371730, ENST00000371733, ENST00000396122, ENST00000493793, | ENST00000343253, ENST00000401026, ENST00000338949, ENST00000334652, ENST00000557479, ENST00000421014, | |
| Fusion gene scores | * DoF score | 10 X 7 X 8=560 | 6 X 8 X 5=240 |
| # samples | 10 | 7 | |
| ** MAII score | log2(10/560*10)=-2.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/240*10)=-1.77760757866355 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: EPS15 [Title/Abstract] AND CCDC18 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | EPS15 | GO:0048268 | clathrin coat assembly | 12807910 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BLCA | TCGA-UY-A78N-01A | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| TCGA | LD | BLCA | TCGA-UY-A78N-01A | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000371730 | ENST00000343253 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| In-frame | ENST00000371730 | ENST00000401026 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| In-frame | ENST00000371730 | ENST00000338949 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| 5CDS-5UTR | ENST00000371730 | ENST00000334652 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| 5CDS-5UTR | ENST00000371730 | ENST00000557479 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| 5CDS-intron | ENST00000371730 | ENST00000421014 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| In-frame | ENST00000371733 | ENST00000343253 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| In-frame | ENST00000371733 | ENST00000401026 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| In-frame | ENST00000371733 | ENST00000338949 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| 5CDS-5UTR | ENST00000371733 | ENST00000334652 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| 5CDS-5UTR | ENST00000371733 | ENST00000557479 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| 5CDS-intron | ENST00000371733 | ENST00000421014 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-3CDS | ENST00000396122 | ENST00000343253 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-3CDS | ENST00000396122 | ENST00000401026 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-3CDS | ENST00000396122 | ENST00000338949 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-5UTR | ENST00000396122 | ENST00000334652 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-5UTR | ENST00000396122 | ENST00000557479 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-intron | ENST00000396122 | ENST00000421014 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-3CDS | ENST00000493793 | ENST00000343253 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-3CDS | ENST00000493793 | ENST00000401026 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-3CDS | ENST00000493793 | ENST00000338949 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-5UTR | ENST00000493793 | ENST00000334652 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-5UTR | ENST00000493793 | ENST00000557479 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| intron-intron | ENST00000493793 | ENST00000421014 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93676359 | + |
| Frame-shit | ENST00000371730 | ENST00000343253 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| Frame-shit | ENST00000371730 | ENST00000401026 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| Frame-shit | ENST00000371730 | ENST00000338949 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| 5CDS-5UTR | ENST00000371730 | ENST00000334652 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| 5CDS-5UTR | ENST00000371730 | ENST00000557479 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| 5CDS-intron | ENST00000371730 | ENST00000421014 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| Frame-shit | ENST00000371733 | ENST00000343253 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| Frame-shit | ENST00000371733 | ENST00000401026 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| Frame-shit | ENST00000371733 | ENST00000338949 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| 5CDS-5UTR | ENST00000371733 | ENST00000334652 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| 5CDS-5UTR | ENST00000371733 | ENST00000557479 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| 5CDS-intron | ENST00000371733 | ENST00000421014 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-3CDS | ENST00000396122 | ENST00000343253 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-3CDS | ENST00000396122 | ENST00000401026 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-3CDS | ENST00000396122 | ENST00000338949 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-5UTR | ENST00000396122 | ENST00000334652 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-5UTR | ENST00000396122 | ENST00000557479 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-intron | ENST00000396122 | ENST00000421014 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-3CDS | ENST00000493793 | ENST00000343253 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-3CDS | ENST00000493793 | ENST00000401026 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-3CDS | ENST00000493793 | ENST00000338949 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-5UTR | ENST00000493793 | ENST00000334652 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-5UTR | ENST00000493793 | ENST00000557479 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
| intron-intron | ENST00000493793 | ENST00000421014 | EPS15 | chr1 | 51934145 | - | CCDC18 | chr1 | 93680303 | + |
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FusionProtFeatures for EPS15_CCDC18 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| EPS15 | CCDC18 |
| Involved in cell growth regulation. May be involved inthe regulation of mitogenic signals and control of cellproliferation. Involved in the internalization of ligand-induciblereceptors of the receptor tyrosine kinase (RTK) type, inparticular EGFR. Plays a role in the assembly of clathrin-coatedpits (CCPs). Acts as a clathrin adapter required for post-Golgitrafficking. Seems to be involved in CCPs maturation includinginvagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1as DAB2-dependent cargo but not TFR seems to require associationwith DAB2. {ECO:0000269|PubMed:16903783,ECO:0000269|PubMed:18362181, ECO:0000269|PubMed:19458185,ECO:0000269|PubMed:22648170}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 15_104 | 103 | 897 | Domain | EH 1 |
| Tgene | >CCDC18 | chr1:51934145 | chr1:93676359 | ENST00000343253 | + | 8 | 29 | 438_464 | 403 | 1455 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >CCDC18 | chr1:51934145 | chr1:93676359 | ENST00000343253 | + | 8 | 29 | 508_1309 | 403 | 1455 | Coiled coil | Ontology_term=ECO:0000255 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 173_184 | 103 | 897 | Calcium binding | Note=1 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 236_247 | 103 | 897 | Calcium binding | Note=2 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 768_850 | 103 | 897 | Compositional bias | Note=Pro-rich |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 128_216 | 103 | 897 | Domain | EH 2 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 160_195 | 103 | 897 | Domain | EF-hand 1 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 223_258 | 103 | 897 | Domain | EF-hand 2 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 224_314 | 103 | 897 | Domain | EH 3 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 851_870 | 103 | 897 | Domain | UIM 1 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 877_896 | 103 | 897 | Domain | UIM 2 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 768_774 | 103 | 897 | Motif | Note=SH3-binding |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 599_827 | 103 | 897 | Region | Note=15 X 3 AA repeats of D-P-F |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 599_601 | 103 | 897 | Repeat | Note=1 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 623_625 | 103 | 897 | Repeat | Note=2 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 629_631 | 103 | 897 | Repeat | Note=3 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 634_636 | 103 | 897 | Repeat | Note=4 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 640_642 | 103 | 897 | Repeat | Note=5 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 645_647 | 103 | 897 | Repeat | Note=6 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 651_653 | 103 | 897 | Repeat | Note=7 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 664_666 | 103 | 897 | Repeat | Note=8 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 672_674 | 103 | 897 | Repeat | Note=9 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 692_694 | 103 | 897 | Repeat | Note=10 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 709_711 | 103 | 897 | Repeat | Note=11 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 737_739 | 103 | 897 | Repeat | Note=12 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 798_800 | 103 | 897 | Repeat | Note=13 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 804_806 | 103 | 897 | Repeat | Note=14 |
| Hgene | >EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 825_827 | 103 | 897 | Repeat | Note=15 |
| Tgene | CCDC18 | chr1:51934145 | chr1:93676359 | ENST00000343253 | + | 8 | 29 | 107_138 | 403 | 1455 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CCDC18 | chr1:51934145 | chr1:93676359 | ENST00000343253 | + | 8 | 29 | 170_402 | 403 | 1455 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for EPS15_CCDC18 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_EPS15_ENST00000371730_chr1_51934145_-_CCDC18_ENST00000343253_chr1_93676359_+_1155aa MAAAAQLSLTQLSSGNPVTEKYTRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS LSSLNLAVPPPRFLKRELFGFKSTLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQES SKLSSLETEPVKLGGHQVESVKDQNQHTMNKQTEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLE SEMTKKCSQLLTLEKQLEEKIVATSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEK KDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNK EKFEKQLKKKSEEVTCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRK MEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQH STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL KQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKE MESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREA HLEARMQAEIKKLSAEVESLKEATHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEA LLTKESELTRLQAKISGHEKAEDIKFLPAPFTSPTEIMPDVQDPKFAKCFHTSFSKCTKLRRSISASDLTFKIHGDEDLSEELLQDLKKM >In-frame_EPS15_ENST00000371730_chr1_51934145_-_CCDC18_ENST00000401026_chr1_93676359_+_1000aa MAAAAQLSLTQLSSGNPVTEKYTRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS LSSLNLAVPPPRFLKRELFGFKSTLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQES SKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQTEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKL ESEMTKKCSQLLTLEKQLEEKIVATSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLE KKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGN KEKFEKQLKKKSEEVTCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLR KMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQ HSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWE LKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMK EMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVRE AHLEARMQAEIKKLSAEVESLKEATHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANE >In-frame_EPS15_ENST00000371730_chr1_51934145_-_CCDC18_ENST00000338949_chr1_93676359_+_704aa MAAAAQLSLTQLSSGNPVTEKYTRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS LSSLNLAVPPPRFLKRELFGFKSTLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQES SKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQTEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKL ESEMTKKCSQLLTLEKQLEEKIVATSSIAAKNAELEQELMLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKE NMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVTCLQKELKIKNHSLQETSEQNVILQHTLQ QQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKM EKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQK >In-frame_EPS15_ENST00000371733_chr1_51934145_-_CCDC18_ENST00000343253_chr1_93676359_+_1155aa MAAAAQLSLTQLSSGNPVTEKYTRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS LSSLNLAVPPPRFLKRELFGFKSTLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQES SKLSSLETEPVKLGGHQVESVKDQNQHTMNKQTEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLE SEMTKKCSQLLTLEKQLEEKIVATSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEK KDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNK EKFEKQLKKKSEEVTCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRK MEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQH STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL KQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKE MESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREA HLEARMQAEIKKLSAEVESLKEATHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEA LLTKESELTRLQAKISGHEKAEDIKFLPAPFTSPTEIMPDVQDPKFAKCFHTSFSKCTKLRRSISASDLTFKIHGDEDLSEELLQDLKKM >In-frame_EPS15_ENST00000371733_chr1_51934145_-_CCDC18_ENST00000401026_chr1_93676359_+_1000aa MAAAAQLSLTQLSSGNPVTEKYTRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS LSSLNLAVPPPRFLKRELFGFKSTLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQES SKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQTEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKL ESEMTKKCSQLLTLEKQLEEKIVATSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLE KKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGN KEKFEKQLKKKSEEVTCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLR KMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQ HSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWE LKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMK EMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVRE AHLEARMQAEIKKLSAEVESLKEATHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANE >In-frame_EPS15_ENST00000371733_chr1_51934145_-_CCDC18_ENST00000338949_chr1_93676359_+_704aa MAAAAQLSLTQLSSGNPVTEKYTRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS LSSLNLAVPPPRFLKRELFGFKSTLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQES SKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQTEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKL ESEMTKKCSQLLTLEKQLEEKIVATSSIAAKNAELEQELMLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKE NMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVTCLQKELKIKNHSLQETSEQNVILQHTLQ QQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKM EKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_EPS15_ENST00000371730_chr1_51934145_-_CCDC18_ENST00000343253_chr1_93676359_+_3465nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATACAGGCAAT ACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGATTTAGCC GACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGAAGTTTCA CTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAAATACCAGATG AGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAAGCTTGCAATA AAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAGCCAAGAAAGT AGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGAAAGCGTAAAAGATCAAAATCAACATACTATGAAC AAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGCTGAAAATTCTGAT TTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAAACTGGAA AGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGCTGCAAAA AATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATAAGGAGTCTAGAAACCAATATTAATACAGAGCATGAGAAAATTTGT TTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAAGAAATGGAAAAGCAGATTGAAAGACTTGAAGCTCAACTAGAGAAA AAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCACTAGAT AGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCTGAA GAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAATAAG GAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAAGAG ACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTAGAA GATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGAAAA ATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTAAAG ATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATGCAC CTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAGCAC AGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGTACT TTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTCACAGCT GAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAACTA AAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTAGAAGGT ACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAACAGCTT CGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATGAAAGAA ATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTGACCCGG GAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCTAGTGAA CTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGTGAAGCT CATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATGATTTCA CATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAGGCAAAA TTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAATGAAGCA TTACTTACTAAAGAATCAGAATTAACCAGATTACAGGCCAAAATTTCTGGACATGAAAAGGCAGAAGACATCAAGTTTCTGCCAGCCCCA TTTACATCTCCAACAGAAATTATGCCTGATGTTCAAGATCCAAAATTTGCTAAATGTTTTCACACATCTTTTTCCAAGTGTACAAAATTA CGTCGCTCTATTAGTGCCAGTGATCTTACTTTCAAAATTCATGGTGATGAAGATCTTTCTGAAGAATTACTACAGGACTTAAAGAAAATG CAATTAGAACAGCCTTCAACATTAGAAGAAAGCCATAAGAATCTGACTTACACCCAGCCAGACTCATTTAAACCTCTCACATATAACCTA GAAGCTGATAGTTCTGAGAATAATGACTTTAACACGCTTAGTGGGATGCTAAGATACATAAACAAAGAAGTAAGACTATTAAAAAAGTCT >In-frame_EPS15_ENST00000371730_chr1_51934145_-_CCDC18_ENST00000401026_chr1_93676359_+_3000nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATACAGGCAAT ACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGATTTAGCC GACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGAAGTTTCA CTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAAATACCAGATG AGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAAGCTTGCAATA AAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAGCCAAGAAAGT AGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGCAGAAAGCGTAAAAGATCAAAATCAACATACTATG AACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGCTGAAAATTCT GATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAAACTG GAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGCTGCA AAAAATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATAAGGAGTCTAGAAACCAATATTAATACAGAGCATGAGAAAATT TGTTTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAAGAAATGGAAAAGCAGATTGAAAGACTTGAAGCTCAACTAGAG AAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCACTA GATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCT GAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAAT AAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAA GAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTA GAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGA AAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTA AAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATG CACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAG CACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGT ACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTCACA GCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAA CTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTAGAA GGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAACAG CTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATGAAA GAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTGACC CGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCTAGT GAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGTGAA GCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATGATT TCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAGGCA AAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAATGAA >In-frame_EPS15_ENST00000371730_chr1_51934145_-_CCDC18_ENST00000338949_chr1_93676359_+_2112nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATACAGGCAAT ACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGATTTAGCC GACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGAAGTTTCA CTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAAATACCAGATG AGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAAGCTTGCAATA AAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAGCCAAGAAAGT AGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGCAGAAAGCGTAAAAGATCAAAATCAACATACTATG AACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGCTGAAAATTCT GATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAAACTG GAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGCTGCA AAAAATGCAGAACTAGAACAGGAGCTTATGCTTGAAGCTCAACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCC ATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAA AATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAA ATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAG GTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAG CAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTG GAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGAT TTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATG GAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACA GAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGG GAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAG GCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAG CAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACT >In-frame_EPS15_ENST00000371733_chr1_51934145_-_CCDC18_ENST00000343253_chr1_93676359_+_3465nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATACAGGCAAT ACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGATTTAGCC GACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGAAGTTTCA CTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAAATACCAGATG AGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAAGCTTGCAATA AAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAGCCAAGAAAGT AGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGAAAGCGTAAAAGATCAAAATCAACATACTATGAAC AAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGCTGAAAATTCTGAT TTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAAACTGGAA AGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGCTGCAAAA AATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATAAGGAGTCTAGAAACCAATATTAATACAGAGCATGAGAAAATTTGT TTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAAGAAATGGAAAAGCAGATTGAAAGACTTGAAGCTCAACTAGAGAAA AAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCACTAGAT AGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCTGAA GAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAATAAG GAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAAGAG ACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTAGAA GATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGAAAA ATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTAAAG ATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATGCAC CTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAGCAC AGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGTACT TTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTCACAGCT GAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAACTA AAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTAGAAGGT ACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAACAGCTT CGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATGAAAGAA ATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTGACCCGG GAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCTAGTGAA CTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGTGAAGCT CATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATGATTTCA CATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAGGCAAAA TTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAATGAAGCA TTACTTACTAAAGAATCAGAATTAACCAGATTACAGGCCAAAATTTCTGGACATGAAAAGGCAGAAGACATCAAGTTTCTGCCAGCCCCA TTTACATCTCCAACAGAAATTATGCCTGATGTTCAAGATCCAAAATTTGCTAAATGTTTTCACACATCTTTTTCCAAGTGTACAAAATTA CGTCGCTCTATTAGTGCCAGTGATCTTACTTTCAAAATTCATGGTGATGAAGATCTTTCTGAAGAATTACTACAGGACTTAAAGAAAATG CAATTAGAACAGCCTTCAACATTAGAAGAAAGCCATAAGAATCTGACTTACACCCAGCCAGACTCATTTAAACCTCTCACATATAACCTA GAAGCTGATAGTTCTGAGAATAATGACTTTAACACGCTTAGTGGGATGCTAAGATACATAAACAAAGAAGTAAGACTATTAAAAAAGTCT >In-frame_EPS15_ENST00000371733_chr1_51934145_-_CCDC18_ENST00000401026_chr1_93676359_+_3000nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATACAGGCAAT ACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGATTTAGCC GACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGAAGTTTCA CTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAAATACCAGATG AGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAAGCTTGCAATA AAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAGCCAAGAAAGT AGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGCAGAAAGCGTAAAAGATCAAAATCAACATACTATG AACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGCTGAAAATTCT GATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAAACTG GAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGCTGCA AAAAATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATAAGGAGTCTAGAAACCAATATTAATACAGAGCATGAGAAAATT TGTTTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAAGAAATGGAAAAGCAGATTGAAAGACTTGAAGCTCAACTAGAG AAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCACTA GATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCT GAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAAT AAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAA GAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTA GAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGA AAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTA AAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATG CACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAG CACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGT ACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTCACA GCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAA CTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTAGAA GGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAACAG CTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATGAAA GAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTGACC CGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCTAGT GAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGTGAA GCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATGATT TCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAGGCA AAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAATGAA >In-frame_EPS15_ENST00000371733_chr1_51934145_-_CCDC18_ENST00000338949_chr1_93676359_+_2112nt ATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATACAGGCAAT ACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGATTTAGCC GACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGAAGTTTCA CTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAAATACCAGATG AGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAAGCTTGCAATA AAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAGCCAAGAAAGT AGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGCAGAAAGCGTAAAAGATCAAAATCAACATACTATG AACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGCTGAAAATTCT GATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAAACTG GAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGCTGCA AAAAATGCAGAACTAGAACAGGAGCTTATGCTTGAAGCTCAACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCC ATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAA AATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAA ATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAG GTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAG CAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTG GAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGAT TTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATG GAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACA GAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGG GAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAG GCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAG CAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_EPS15_ENST00000371730_chr1_51934145_-_CCDC18_ENST00000343253_chr1_93676359_+_3475nt TGGAAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGA TACAGGCAATACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTG GGATTTAGCCGACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATT GGAAGTTTCACTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAA ATACCAGATGAGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAA GCTTGCAATAAAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAG CCAAGAAAGTAGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGAAAGCGTAAAAGATCAAAATCAACA TACTATGAACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGCTGA AAATTCTGATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAG CAAACTGGAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTAT TGCTGCAAAAAATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATAAGGAGTCTAGAAACCAATATTAATACAGAGCATGA GAAAATTTGTTTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAAGAAATGGAAAAGCAGATTGAAAGACTTGAAGCTCA ACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGA ATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCA AGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGA AGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAG TCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGG AGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAA GTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAG GCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAA AGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAA GTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATT AAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGA TCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAA TTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAA ATTAGAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAA AGAACAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAG GATGAAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAG GCTGACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCT CTCTAGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGT ACGTGAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGA GATGATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGA GAAGGCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGC AAATGAAGCATTACTTACTAAAGAATCAGAATTAACCAGATTACAGGCCAAAATTTCTGGACATGAAAAGGCAGAAGACATCAAGTTTCT GCCAGCCCCATTTACATCTCCAACAGAAATTATGCCTGATGTTCAAGATCCAAAATTTGCTAAATGTTTTCACACATCTTTTTCCAAGTG TACAAAATTACGTCGCTCTATTAGTGCCAGTGATCTTACTTTCAAAATTCATGGTGATGAAGATCTTTCTGAAGAATTACTACAGGACTT AAAGAAAATGCAATTAGAACAGCCTTCAACATTAGAAGAAAGCCATAAGAATCTGACTTACACCCAGCCAGACTCATTTAAACCTCTCAC ATATAACCTAGAAGCTGATAGTTCTGAGAATAATGACTTTAACACGCTTAGTGGGATGCTAAGATACATAAACAAAGAAGTAAGACTATT >In-frame_EPS15_ENST00000371730_chr1_51934145_-_CCDC18_ENST00000401026_chr1_93676359_+_3140nt TGGAAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGA TACAGGCAATACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTG GGATTTAGCCGACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATT GGAAGTTTCACTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAA ATACCAGATGAGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAA GCTTGCAATAAAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAG CCAAGAAAGTAGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGCAGAAAGCGTAAAAGATCAAAATCA ACATACTATGAACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGC TGAAAATTCTGATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTC CAGCAAACTGGAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTC TATTGCTGCAAAAAATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATAAGGAGTCTAGAAACCAATATTAATACAGAGCA TGAGAAAATTTGTTTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAAGAAATGGAAAAGCAGATTGAAAGACTTGAAGC TCAACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCT TGAATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAA CCAAGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATT GGAAGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCA CAGTCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAA TGGAGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGA AAAGTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGC CAGGCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAA TAAAGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGA AAAGTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGA ATTAAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAA GGATCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAG AAATTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAAT TAAATTAGAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGC TAAAGAACAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACA AAGGATGAAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATT GAGGCTGACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAG GCTCTCTAGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAA AGTACGTGAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATAT GGAGATGATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTT AGAGAAGGCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGC TGCAAATGAAGCATTACTTACTAAAGGAGAAAATGTGTAATTCAAAGAAGATACTGATGTGTTGAAAAAATGGAATTTTTGGTACTGTGC >In-frame_EPS15_ENST00000371730_chr1_51934145_-_CCDC18_ENST00000338949_chr1_93676359_+_3114nt TGGAAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGA TACAGGCAATACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTG GGATTTAGCCGACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATT GGAAGTTTCACTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAA ATACCAGATGAGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAA GCTTGCAATAAAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAG CCAAGAAAGTAGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGCAGAAAGCGTAAAAGATCAAAATCA ACATACTATGAACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGC TGAAAATTCTGATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTC CAGCAAACTGGAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTC TATTGCTGCAAAAAATGCAGAACTAGAACAGGAGCTTATGCTTGAAGCTCAACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAA GACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAAT GAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTC AGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAA ATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCA TACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGT GTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACA TGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCT GTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCA GACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTT GCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGT ACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGA AGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTT GGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTAGAAGGTACTCTGGAGAAATCAGAATTGGAACTTAA AGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAACAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAA TGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATGAAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACA GTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTGACCCGGGAGCAGGTGCAGAACTCTCATACAGAATT GGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCTAGTGAACTGGAGGATATGAAGCAACTCTCTAAAGA GAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGTGAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAAT CAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATGATTTCACATCAAGAGAACCATGCAAAGTGGAAGAT TTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAGGCAAAATTGGAATTAGAAGAAGCTCAGGATACTGT AAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAATGAAGCATTACTTACTAAAGGAGAAAATGTGTAATT CAAAGAAGATACTGATGTGTTGAAAAAATGGAATTTTTGGTACTGTGCTGTTTACTTATTATATGTAGCTCATACTTCATAGAAGCTGTT ATTTTGCTTTTGAATAAATTTTATATTTCAATATTTTAAAAGAAAGCCCTTCTAAAACTTAATTATATTTTTAAAGAAAATTTATTATTT >In-frame_EPS15_ENST00000371733_chr1_51934145_-_CCDC18_ENST00000343253_chr1_93676359_+_3562nt GCCCCGGCCTCGCCTGCGGCCGCTCCCTCCGCCTCCTCCCCGCCCCGAGCCCCAGTCAGCCCGTCTTCCTTCCCCTCCCTTGCATGATGG AAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATAC AGGCAATACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGA TTTAGCCGACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGA AGTTTCACTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAAATA CCAGATGAGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAAGCT TGCAATAAAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAGCCA AGAAAGTAGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGAAAGCGTAAAAGATCAAAATCAACATAC TATGAACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGCTGAAAA TTCTGATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAGCAA ACTGGAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTATTGC TGCAAAAAATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATAAGGAGTCTAGAAACCAATATTAATACAGAGCATGAGAA AATTTGTTTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAAGAAATGGAAAAGCAGATTGAAAGACTTGAAGCTCAACT AGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATC ACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGT ATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGG AAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCT TCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGA GCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTT GAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCA AGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGC AATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTT ACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAA AAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCT CACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTG GGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATT AGAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGA ACAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGAT GAAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCT GACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTC TAGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACG TGAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGAT GATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAA GGCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAA TGAAGCATTACTTACTAAAGAATCAGAATTAACCAGATTACAGGCCAAAATTTCTGGACATGAAAAGGCAGAAGACATCAAGTTTCTGCC AGCCCCATTTACATCTCCAACAGAAATTATGCCTGATGTTCAAGATCCAAAATTTGCTAAATGTTTTCACACATCTTTTTCCAAGTGTAC AAAATTACGTCGCTCTATTAGTGCCAGTGATCTTACTTTCAAAATTCATGGTGATGAAGATCTTTCTGAAGAATTACTACAGGACTTAAA GAAAATGCAATTAGAACAGCCTTCAACATTAGAAGAAAGCCATAAGAATCTGACTTACACCCAGCCAGACTCATTTAAACCTCTCACATA TAACCTAGAAGCTGATAGTTCTGAGAATAATGACTTTAACACGCTTAGTGGGATGCTAAGATACATAAACAAAGAAGTAAGACTATTAAA >In-frame_EPS15_ENST00000371733_chr1_51934145_-_CCDC18_ENST00000401026_chr1_93676359_+_3227nt GCCCCGGCCTCGCCTGCGGCCGCTCCCTCCGCCTCCTCCCCGCCCCGAGCCCCAGTCAGCCCGTCTTCCTTCCCCTCCCTTGCATGATGG AAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATAC AGGCAATACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGA TTTAGCCGACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGA AGTTTCACTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAAATA CCAGATGAGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAAGCT TGCAATAAAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAGCCA AGAAAGTAGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGCAGAAAGCGTAAAAGATCAAAATCAACA TACTATGAACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGCTGA AAATTCTGATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAG CAAACTGGAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTAT TGCTGCAAAAAATGCAGAACTAGAACAGGAGCTTATGGAAAAGAATGAAAAGATAAGGAGTCTAGAAACCAATATTAATACAGAGCATGA GAAAATTTGTTTAGCCTTTGAAAAAGCAAAGAAAATTCACTTGGAACAGCATAAAGAAATGGAAAAGCAGATTGAAAGACTTGAAGCTCA ACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGACTATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGA ATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAAAAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCA AGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGCATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGA AGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATCTGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAG TCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATACTCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGG AGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTCAAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAA GTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGAAGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAG GCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTCTAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAA AGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCAGACAAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAA GTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCAAAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATT AAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACTACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGA TCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGACAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAA TTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGATATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAA ATTAGAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGAATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAA AGAACAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGAACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAG GATGAAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTACATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAG GCTGACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGCAGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCT CTCTAGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAAAGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGT ACGTGAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAAGAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGA GATGATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTCTGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGA GAAGGCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAGCAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGC AAATGAAGCATTACTTACTAAAGGAGAAAATGTGTAATTCAAAGAAGATACTGATGTGTTGAAAAAATGGAATTTTTGGTACTGTGCTGT >In-frame_EPS15_ENST00000371733_chr1_51934145_-_CCDC18_ENST00000338949_chr1_93676359_+_3201nt GCCCCGGCCTCGCCTGCGGCCGCTCCCTCCGCCTCCTCCCCGCCCCGAGCCCCAGTCAGCCCGTCTTCCTTCCCCTCCCTTGCATGATGG AAACACCATGGCTGCGGCGGCCCAGCTCTCTCTGACACAGTTATCAAGTGGGAATCCTGTATATGAAAAATACTATAGACAGGTTGATAC AGGCAATACTGGAAGGGTGTTGGCTTCTGATGCTGCTGCTTTCCTGAAAAAATCAGGGCTTCCAGACTTGATACTTGGAAAGATTTGGGA TTTAGCCGACACAGATGGCAAAGGTATCCTGAACAAACAAGAATTCTTTGTTGCTTTGCGTCTTGTGGCATGTGCCCAGAATGGATTGGA AGTTTCACTAAGTAGTTTGAACCTGGCTGTTCCTCCACCAAGATTTTTAAAAAGAGAATTATTTGGCTTTAAATCATATCTTTCTAAATA CCAGATGAGTAGCTTCTCAAACAAGGAAGACCGTTGCATTGGCTGCTGTGAGGCAAATAAATTGGTGATTTCGGAATTGAGAATTAAGCT TGCAATAAAAGAGGCAGAAATTCAAAAGCTTCATGCAAACCTGACTGCAAATCAGTTATCTCAGAGTCTTATTACTTGTAATGACAGCCA AGAAAGTAGCAAATTAAGTAGTTTAGAAACAGAACCTGTAAAGCTAGGTGGTCATCAAGTAGCAGAAAGCGTAAAAGATCAAAATCAACA TACTATGAACAAGCAATATGAAAAAGAGAGGCAAAGACTTGTTACTGGAATAGAAGAACTACGTACTAAGCTGATACAAATAGAAGCTGA AAATTCTGATTTGAAGGTTAACATGGCTCACAGAACTAGTCAGTTTCAGCTGATTCAAGAGGAGCTGCTAGAGAAAGCTTCAAACTCCAG CAAACTGGAAAGTGAAATGACAAAGAAATGTTCTCAACTTTTAACTCTTGAGAAACAGCTGGAAGAAAAGATAGTTGCTTATTCCTCTAT TGCTGCAAAAAATGCAGAACTAGAACAGGAGCTTATGCTTGAAGCTCAACTAGAGAAAAAGGACCAACAATTTAAAGAACAAGAAAAGAC TATGTCCATGTTGCAACAAGATATAATATGCAAACAACATCATCTTGAATCACTAGATAGACTCTTGACGGAAAGCAAAGGGGAAATGAA AAAGGAAAATATGAAGAAAGATGAAGCTTTAAAAGCATTACAGAACCAAGTATCTGAAGAAACAATCAAGGTTAGGCAACTAGATTCAGC ATTGGAAATTTGTAAGGAAGAACTTGTCTTGCATTTGAATCAATTGGAAGGAAATAAGGAAAAGTTTGAAAAACAGTTAAAGAAGAAATC TGAAGAGGTATATTGTTTACAGAAAGAGCTAAAGATAAAAAATCACAGTCTTCAAGAGACTTCTGAGCAAAACGTTATTCTACAGCATAC TCTTCAGCAACAGCAGCAAATGTTACAACAAGAGACAATTAGAAATGGAGAGCTAGAAGATACTCAAACTAAACTTGAAAAACAGGTGTC AAAACTGGAACAAGAACTTCAAAAACAAAGGGAAAGTTCAGCTGAAAAGTTGAGAAAAATGGAGGAGAAATGTGAATCAGCTGCACATGA AGCAGATTTGAAAAGGCAAAAAGTGATTGAGCTTACTGGCACTGCCAGGCAAGTAAAGATTGAGATGGATCAGTACAAAGAAGAGCTGTC TAAAATGGAAAAGGAAATAATGCACCTAAAACGAGATGGAGAAAATAAAGCAATGCACCTCTCTCAATTAGATATGATCTTAGATCAGAC AAAGACAGAGCTAGAAAAGAAAACAAATGCTGTAAAGGAGTTAGAAAAGTTACAGCACAGTACTGAAACTGAACTAACAGAAGCCTTGCA AAAACGGGAAGTACTTGAGACTGAACTACAAAATGCTCATGGAGAATTAAAAAGTACTTTAAGACAACTCCAGGAATTGAGAGATGTACT ACAGAAGGCTCAATTATCATTAGAGGAAAAATACACTACTATAAAGGATCTCACAGCTGAACTTAGAGAATGCAAGATGGAGATTGAAGA CAAAAAGCAGGAGCTCCTTGAAATGGATCAGGCACTTAAAGAGAGAAATTGGGAACTAAAGCAAAGAGCAGCTCAGGTTACACATTTGGA TATGACTATTCGTGAGCACAGAGGAGAAATGGAACAAAAAATAATTAAATTAGAAGGTACTCTGGAGAAATCAGAATTGGAACTTAAAGA ATGTAACAAACAGATAGAAAGTCTGAATGACAAATTACAAAATGCTAAAGAACAGCTTCGAGAAAAAGAGTTTATAATGCTACAAAATGA ACAGGAGATAAGTCAACTGAAAAAAGAAATTGAAAGAACACAACAAAGGATGAAAGAAATGGAGAGTGTTATGAAAGAGCAAGAACAGTA CATTGCCACTCAGTACAAGGAGGCCATAGATTTGGGGCAAGAATTGAGGCTGACCCGGGAGCAGGTGCAGAACTCTCATACAGAATTGGC AGAGGCTCGTCATCAGCAAGTCCAAGCACAGAGAGAAATAGAAAGGCTCTCTAGTGAACTGGAGGATATGAAGCAACTCTCTAAAGAGAA AGATGCTCATGGAAACCATTTAGCTGAAGAACTGGGGGCTTCTAAAGTACGTGAAGCTCATTTAGAAGCAAGAATGCAAGCAGAAATCAA GAAATTGTCAGCAGAAGTAGAATCTCTCAAAGAAGCTTATCATATGGAGATGATTTCACATCAAGAGAACCATGCAAAGTGGAAGATTTC TGCTGACTCTCAAAAGTCTTCTGTTCAGCAACTAAACGAACAGTTAGAGAAGGCAAAATTGGAATTAGAAGAAGCTCAGGATACTGTAAG CAATTTGCATCAACAAGTCCAAGATAGGAATGAAGTAATTGAAGCTGCAAATGAAGCATTACTTACTAAAGGAGAAAATGTGTAATTCAA AGAAGATACTGATGTGTTGAAAAAATGGAATTTTTGGTACTGTGCTGTTTACTTATTATATGTAGCTCATACTTCATAGAAGCTGTTATT TTGCTTTTGAATAAATTTTATATTTCAATATTTTAAAAGAAAGCCCTTCTAAAACTTAATTATATTTTTAAAGAAAATTTATTATTTTAT |
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FusionGenePPI for EPS15_CCDC18 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| EPS15 | RNF11, SNAP91, AGFG1, NAGPA, STON2, HGS, AP2A2, DNM2, AP2A1, EGFR, CLINT1, EPN1, SCAMP1, STAM2, GRB2, CRK, RAB11FIP2, REPS2, UBE2D1, UBE2D2, UBE2D3, UBE2H, UBE2E1, SLC6A3, PARK2, USP8, CD4, EPS15, OCLN, UBQLN1, UBC, NEDD4, GJA1, TGFB1, FCHO2, ITSN1, ITSN2, ELAVL1, RAD23A, UBQLN2, EPN3, SH3BP4, AP1B1, NUMB, SPG20, TFAP2A, ABL1, AP2B1, IQGAP1, KRT85, KRT1, KRT10, KRT2, AP2M1, KRT14, KRT86, KRT5, KRT6A, KRT16, KRT9, HSPA8, KRT35, HSPA9, KRT17, KRT33B, KRT83, BMP2K, KRT34, KRT82, NONO, KRT38, KRT75, KRT79, PRDX1, KRT36, KRT32, MAP4, HSPA1L, HSPA1B, KRT37, HSPA5, KRT73, AP2S1, NECAP2, TRAF2, MCCC2, KRT4, ACTB, KRT3, VPRBP, TUBB, HIST4H4, PCCB, KRTAP9-3, NECAP1, VSIG8, CCT3, CRKL, FN1, VCAM1, LAPTM5, ITGA4, OPTN, RABL6, EPHA2, CORO7, AGFG2, SLC25A41, AURKA, SPC25, NTRK1, TMEM17, XPO1, CAPZA2, CLTB, CLTC, DBN1, FLNA, GAK, MYH9, PPP1CB, PICALM, PDLIM7, SYNPO, MAPRE1, LIMA1, GTSE1, ANLN, MYO19, MAPK14, AP1G1, MYO6, SPOPL, SGIP1, FCHO1, CDH1, RUNDC3A, LSR, STAMBPL1, CCDC172, OXCT1, MTNR1A, RNF26 | CCDC18 | COG3, MED4, OFD1, PCM1, CEP128, CEP135, CEP63, ODF2, POC5, DYNLL1, FGFR1OP, CCDC14, KIF7, EYA2, TPTE2, EMILIN1, FAM167A, CDR2, PRPF19, NDEL1, GALK2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | EPS15 | chr1:51934145 | chr1:93676359 | ENST00000371733 | - | 5 | 25 | 2_330 | 103 | 897 | DAB2 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for EPS15_CCDC18 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for EPS15_CCDC18 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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