FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 11680

FusionGeneSummary for EP300_BCOR

check button Fusion gene summary
Fusion gene informationFusion gene name: EP300_BCOR
Fusion gene ID: 11680
HgeneTgene
Gene symbol

EP300

BCOR

Gene ID

2033

54880

Gene nameE1A binding protein p300BCL6 corepressor
SynonymsKAT3B|RSTS2|p300ANOP2|MAA2|MCOPS2
Cytomap

22q13.2

Xp11.4

Type of geneprotein-codingprotein-coding
Descriptionhistone acetyltransferase p300E1A-associated protein p300E1A-binding protein, 300kDhistone butyryltransferase p300histone crotonyltransferase p300p300 HATprotein propionyltransferase p300BCL-6 corepressorBCL-6 interacting corepressor
Modification date2018052720180527
UniProtAcc

Q09472

Q6W2J9

Ensembl transtripts involved in fusion geneENST00000263253, ENST00000378455, 
ENST00000342274, ENST00000378463, 
ENST00000397354, ENST00000378444, 
Fusion gene scores* DoF score16 X 11 X 11=19361 X 1 X 1=1
# samples 172
** MAII scorelog2(17/1936*10)=-3.50947230113689
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/1*10)=4.32192809488736
Context

PubMed: EP300 [Title/Abstract] AND BCOR [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneEP300

GO:0000122

negative regulation of transcription by RNA polymerase II

10733570

HgeneEP300

GO:0001666

response to hypoxia

9887100|15261140

HgeneEP300

GO:0006355

regulation of transcription, DNA-templated

15261140

HgeneEP300

GO:0006473

protein acetylation

21030595|24939902

HgeneEP300

GO:0006475

internal protein amino acid acetylation

18722353

HgeneEP300

GO:0010742

macrophage derived foam cell differentiation

26504087

HgeneEP300

GO:0016573

histone acetylation

25818647

HgeneEP300

GO:0018076

N-terminal peptidyl-lysine acetylation

12435739

HgeneEP300

GO:0018393

internal peptidyl-lysine acetylation

17403783

HgeneEP300

GO:0018394

peptidyl-lysine acetylation

23962722

HgeneEP300

GO:0032460

negative regulation of protein oligomerization

23962722

HgeneEP300

GO:0034644

cellular response to UV

24939902

HgeneEP300

GO:0042771

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

17403783

HgeneEP300

GO:0043627

response to estrogen

11581164

HgeneEP300

GO:0043923

positive regulation by host of viral transcription

16687403

HgeneEP300

GO:0043969

histone H2B acetylation

23415232

HgeneEP300

GO:0045815

positive regulation of gene expression, epigenetic

25818647

HgeneEP300

GO:0045944

positive regulation of transcription by RNA polymerase II

12586840|18722353

HgeneEP300

GO:0051091

positive regulation of DNA binding transcription factor activity

10518217|25818647

HgeneEP300

GO:0060765

regulation of androgen receptor signaling pathway

18487222

HgeneEP300

GO:0061921

peptidyl-lysine propionylation

17267393

HgeneEP300

GO:0090043

regulation of tubulin deacetylation

18722353

HgeneEP300

GO:0140066

peptidyl-lysine crotonylation

25818647

HgeneEP300

GO:0140067

peptidyl-lysine butyrylation

17267393

TgeneBCOR

GO:0035518

histone H2A monoubiquitination

16943429

TgeneBCOR

GO:0045892

negative regulation of transcription, DNA-templated

10898795


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLGGTCGA-DU-6404-01AEP300chr22

41572532

+BCORchrX

39930412

-
TCGARVLGGTCGA-DU-6404-02BEP300chr22

41572532

+BCORchrX

39930412

-
TCGALDLGGTCGA-DU-6404-01AEP300chr22

41573820

+BCORchrX

39930412

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000263253ENST00000378455EP300chr22

41572532

+BCORchrX

39930412

-
In-frameENST00000263253ENST00000342274EP300chr22

41572532

+BCORchrX

39930412

-
5CDS-intronENST00000263253ENST00000378463EP300chr22

41572532

+BCORchrX

39930412

-
5CDS-intronENST00000263253ENST00000397354EP300chr22

41572532

+BCORchrX

39930412

-
5CDS-intronENST00000263253ENST00000378444EP300chr22

41572532

+BCORchrX

39930412

-
Frame-shiftENST00000263253ENST00000378455EP300chr22

41573820

+BCORchrX

39930412

-
Frame-shiftENST00000263253ENST00000342274EP300chr22

41573820

+BCORchrX

39930412

-
5CDS-intronENST00000263253ENST00000378463EP300chr22

41573820

+BCORchrX

39930412

-
5CDS-intronENST00000263253ENST00000397354EP300chr22

41573820

+BCORchrX

39930412

-
5CDS-intronENST00000263253ENST00000378444EP300chr22

41573820

+BCORchrX

39930412

-

Top

FusionProtFeatures for EP300_BCOR


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EP300

Q09472

BCOR

Q6W2J9

Functions as histone acetyltransferase and regulatestranscription via chromatin remodeling (PubMed:23415232,PubMed:23934153, PubMed:8945521). Acetylates all four corehistones in nucleosomes. Histone acetylation gives an epigenetictag for transcriptional activation (PubMed:23415232,PubMed:23934153, PubMed:8945521). Mediates cAMP-gene regulation bybinding specifically to phosphorylated CREB protein. Mediatesacetylation of histone H3 at 'Lys-122' (H3K122ac), a modificationthat localizes at the surface of the histone octamer andstimulates transcription, possibly by promoting nucleosomeinstability. Mediates acetylation of histone H3 at 'Lys-27'(H3K27ac) (PubMed:23911289). Also functions as acetyltransferasefor nonhistone targets. Acetylates 'Lys-131' of ALX1 and acts asits coactivator (PubMed:12929931). Acetylates SIRT2 and isproposed to indirectly increase the transcriptional activity ofTP53 through acetylation and subsequent attenuation of SIRT2deacetylase function (PubMed:18722353). Acetylates HDAC1 leadingto its inactivation and modulation of transcription(PubMed:16762839). Acts as a TFAP2A-mediated transcriptionalcoactivator in presence of CITED2 (PubMed:12586840). Plays a roleas a coactivator of NEUROD1-dependent transcription of thesecretin and p21 genes and controls terminal differentiation ofcells in the intestinal epithelium. Promotes cardiac myocyteenlargement. Can also mediate transcriptional repression.Acetylates FOXO1 and enhances its transcriptional activity(PubMed:15890677). Acetylates BCL6 wich disrupts its ability torecruit histone deacetylases and hinders its transcriptionalrepressor activity (PubMed:12402037). Participates in CLOCK orNPAS2-regulated rhythmic gene transcription; exhibits a circadianassociation with CLOCK or NPAS2, correlating with increase inPER1/2 mRNA and histone H3 acetylation on the PER1/2 promoter(PubMed:14645221). Acetylates MTA1 at 'Lys-626' which is essentialfor its transcriptional coactivator activity (PubMed:16617102).Acetylates XBP1 isoform 2; acetylation increases protein stabilityof XBP1 isoform 2 and enhances its transcriptional activity(PubMed:20955178). Acetylates PCNA; acetylation promotes removalof chromatin-bound PCNA and its degradation during nucleotideexcision repair (NER) (PubMed:24939902). Acetylates MEF2D(PubMed:21030595). Acetylates and stabilizes ZBTB7B protein byantagonizing ubiquitin conjugation and degragation, this mechanismmay be involved in CD4/CD8 lineage differentiation(PubMed:20810990). In addition to protein acetyltransferase, canuse different acyl-CoA substrates, such as (2E)-butenoyl-CoA(crotonyl-CoA), butanoyl-CoA (butyryl-CoA) or propanoyl-CoA(propionyl-CoA), and is able to mediate protein crotonylation,butyrylation or propionylation, respectively (PubMed:25818647,PubMed:17267393). Acts as a histone crotonyltransferase;crotonylation marks active promoters and enhancers and confersresistance to transcriptional repressors (PubMed:25818647).Histone crotonyltransferase activity is dependent on theconcentration of (2E)-butenoyl-CoA (crotonyl-CoA) substrate andsuch activity is weak when (E)-but-2-enoyl-CoA (crotonyl-CoA)concentration is low (PubMed:25818647). Also acts as a histonebutyryltransferase; butyrylation marks active promoters(PubMed:17267393). {ECO:0000250|UniProtKB:B2RWS6,ECO:0000269|PubMed:10733570, ECO:0000269|PubMed:11430825,ECO:0000269|PubMed:11701890, ECO:0000269|PubMed:12402037,ECO:0000269|PubMed:12586840, ECO:0000269|PubMed:12929931,ECO:0000269|PubMed:14645221, ECO:0000269|PubMed:15186775,ECO:0000269|PubMed:15890677, ECO:0000269|PubMed:16617102,ECO:0000269|PubMed:16762839, ECO:0000269|PubMed:17267393,ECO:0000269|PubMed:18722353, ECO:0000269|PubMed:18995842,ECO:0000269|PubMed:20810990, ECO:0000269|PubMed:21030595,ECO:0000269|PubMed:23415232, ECO:0000269|PubMed:23911289,ECO:0000269|PubMed:23934153, ECO:0000269|PubMed:24939902,ECO:0000269|PubMed:25818647, ECO:0000269|PubMed:8945521,ECO:0000305|PubMed:20955178}. (Microbial infection) In case of HIV-1 infection, it isrecruited by the viral protein Tat. Regulates Tat'stransactivating activity and may help inducing chromatinremodeling of proviral genes. Binds to and may be involved in thetransforming capacity of the adenovirus E1A protein.{ECO:0000269|PubMed:10545121, ECO:0000269|PubMed:11080476}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30311519_152616872415Compositional biasNote=Poly-Glu
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+3031797_80016872415Compositional biasNote=Poly-Ser
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30311067_113916872415DomainBromo
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30311287_166316872415DomainCBP/p300-type HAT
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+3031566_64516872415DomainKIX
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+303111_1716872415MotifNuclear localization signal
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30311017_102916872415RegionNote=CRD1%3B mediates transcriptional repression
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30311398_140016872415RegionAcetyl-CoA binding
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30311410_141116872415RegionAcetyl-CoA binding
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+3031331_41716872415Zinc fingerTAZ-type 1
TgeneBCORchr22:41572532chrX:39930412ENST00000342274-4151625_163110171722Compositional biasNote=Poly-Asp
TgeneBCORchr22:41572532chrX:39930412ENST00000378444-4151625_163110171756Compositional biasNote=Poly-Asp
TgeneBCORchr22:41572532chrX:39930412ENST00000378455-3141625_16319991704Compositional biasNote=Poly-Asp
TgeneBCORchr22:41572532chrX:39930412ENST00000397354-4151625_163110171722Compositional biasNote=Poly-Asp
TgeneBCORchr22:41572532chrX:39930412ENST00000342274-4151462_149510171722RepeatNote=ANK 1
TgeneBCORchr22:41572532chrX:39930412ENST00000342274-4151496_152510171722RepeatNote=ANK 2
TgeneBCORchr22:41572532chrX:39930412ENST00000342274-4151529_155810171722RepeatNote=ANK 3
TgeneBCORchr22:41572532chrX:39930412ENST00000378444-4151462_149510171756RepeatNote=ANK 1
TgeneBCORchr22:41572532chrX:39930412ENST00000378444-4151496_152510171756RepeatNote=ANK 2
TgeneBCORchr22:41572532chrX:39930412ENST00000378444-4151529_155810171756RepeatNote=ANK 3
TgeneBCORchr22:41572532chrX:39930412ENST00000378455-3141462_14959991704RepeatNote=ANK 1
TgeneBCORchr22:41572532chrX:39930412ENST00000378455-3141496_15259991704RepeatNote=ANK 2
TgeneBCORchr22:41572532chrX:39930412ENST00000378455-3141529_15589991704RepeatNote=ANK 3
TgeneBCORchr22:41572532chrX:39930412ENST00000397354-4151462_149510171722RepeatNote=ANK 1
TgeneBCORchr22:41572532chrX:39930412ENST00000397354-4151496_152510171722RepeatNote=ANK 2
TgeneBCORchr22:41572532chrX:39930412ENST00000397354-4151529_155810171722RepeatNote=ANK 3

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30312066_206916872415Compositional biasNote=Poly-Gln
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30312190_219516872415Compositional biasNote=Poly-Gln
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30311572_181816872415RegionNote=Binding region for E1A adenovirus
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30311664_170716872415Zinc fingerZZ-type
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30311728_180916872415Zinc fingerTAZ-type 2
TgeneBCORchr22:41572532chrX:39930412ENST00000342274-415634_71110171722Compositional biasNote=Pro-rich
TgeneBCORchr22:41572532chrX:39930412ENST00000378444-415634_71110171756Compositional biasNote=Pro-rich
TgeneBCORchr22:41572532chrX:39930412ENST00000378455-314634_7119991704Compositional biasNote=Pro-rich
TgeneBCORchr22:41572532chrX:39930412ENST00000397354-415634_71110171722Compositional biasNote=Pro-rich


Top

FusionGeneSequence for EP300_BCOR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_EP300_ENST00000263253_chr22_41572532_+_BCOR_ENST00000378455_chrX_39930412_-_2392aa
MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGDINQLQTSLGMVQDAASKHKQLSELLRSGSS
PNLNMGVGGPGQVMASQAQQSSPGLGLINSMVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAA
GNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGASGL
GLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE
VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPSSLGVGQQSA
PNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ
NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYY
HLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM
AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPP
GSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPS
LPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPA
DTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVD
PQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEF
SPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVL
HHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMA
ESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPP
SEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKRE
ENTSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIP
CDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCERAMMRFSELEMKEREGGHPATKD
SEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERCEYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTL
RVDRKRKVSGDSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITE
EKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAA
SLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQL
PCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN
CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGY
DVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSAS

>In-frame_EP300_ENST00000263253_chr22_41572532_+_BCOR_ENST00000342274_chrX_39930412_-_2392aa
MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGDINQLQTSLGMVQDAASKHKQLSELLRSGSS
PNLNMGVGGPGQVMASQAQQSSPGLGLINSMVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAA
GNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGASGL
GLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE
VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPSSLGVGQQSA
PNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ
NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYY
HLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM
AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPP
GSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPS
LPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPA
DTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVD
PQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEF
SPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVL
HHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMA
ESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPP
SEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKRE
ENTSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIP
CDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCERAMMRFSELEMKEREGGHPATKD
SEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERCEYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTL
RVDRKRKVSGDSSHTETTAEEVPEDPLLKAKRRRVSKGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITE
EKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAA
SLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQL
PCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN
CSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGY
DVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSAS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_EP300_ENST00000263253_chr22_41572532_+_BCOR_ENST00000378455_chrX_39930412_-_7176nt
ATGGCCGAGAATGTGGTGGAACCGGGGCCGCCTTCAGCCAAGCGGCCTAAACTCTCATCTCCGGCCCTCTCGGCGTCCGCCAGCGATGGC
ACAGATTTTGGCTCTCTATTTGACTTGGAGCACGACTTACCAGATGAATTAATCAACTCTACAGAATTGGGACTAACCAATGGTGGTGAT
ATTAATCAGCTTCAGACAAGTCTTGGCATGGTACAAGATGCAGCTTCTAAACATAAACAGCTGTCAGAATTGCTGCGATCTGGTAGTTCC
CCTAACCTCAATATGGGAGTTGGTGGCCCAGGTCAAGTCATGGCCAGCCAGGCCCAACAGAGCAGTCCTGGATTAGGTTTGATAAATAGC
ATGGTCAAAAGCCCAATGACACAGGCAGGCTTGACTTCTCCCAACATGGGGATGGGCACTAGTGGACCAAATCAGGGTCCTACGCAGTCA
ACAGGTATGATGAACAGTCCAGTAAATCAGCCTGCCATGGGAATGAACACAGGGATGAATGCGGGCATGAATCCTGGAATGTTGGCTGCA
GGCAATGGACAAGGGATAATGCCTAATCAAGTCATGAACGGTTCAATTGGAGCAGGCCGAGGGCGACAGAATATGCAGTACCCAAACCCA
GGCATGGGAAGTGCTGGCAACTTACTGACTGAGCCTCTTCAGCAGGGCTCTCCCCAGATGGGAGGACAAACAGGATTGAGAGGCCCCCAG
CCTCTTAAGATGGGAATGATGAACAACCCCAATCCTTATGGTTCACCATATACTCAGAATCCTGGACAGCAGATTGGAGCCAGTGGCCTT
GGTCTCCAGATTCAGACAAAAACTGTACTATCAAATAACTTATCTCCATTTGCTATGGACAAAAAGGCAGTTCCTGGTGGAGGAATGCCC
AACATGGGTCAACAGCCAGCCCCGCAGGTCCAGCAGCCAGGCCTGGTGACTCCAGTTGCCCAAGGGATGGGTTCTGGAGCACATACAGCT
GATCCAGAGAAGCGCAAGCTCATCCAGCAGCAGCTTGTTCTCCTTTTGCATGCTCACAAGTGCCAGCGCCGGGAACAGGCCAATGGGGAA
GTGAGGCAGTGCAACCTTCCCCACTGTCGCACAATGAAGAATGTCCTAAACCACATGACACACTGCCAGTCAGGCAAGTCTTGCCAAGTG
GCACACTGTGCATCTTCTCGACAAATCATTTCACACTGGAAGAATTGTACAAGACATGATTGTCCTGTGTGTCTCCCCCTCAAAAATGCT
GGTGATAAGAGAAATCAACAGCCAATTTTGACTGGAGCACCCGTTGGACTTGGAAATCCTAGCTCTCTAGGGGTGGGTCAACAGTCTGCC
CCCAACCTAAGCACTGTTAGTCAGATTGATCCCAGCTCCATAGAAAGAGCCTATGCAGCTCTTGGACTACCCTATCAAGTAAATCAGATG
CCGACACAACCCCAGGTGCAAGCAAAGAACCAGCAGAATCAGCAGCCTGGGCAGTCTCCCCAAGGCATGCGGCCCATGAGCAACATGAGT
GCTAGTCCTATGGGAGTAAATGGAGGTGTAGGAGTTCAAACGCCGAGTCTTCTTTCTGACTCAATGTTGCATTCAGCCATAAATTCTCAA
AACCCAATGATGAGTGAAAATGCCAGTGTGCCCTCCCTGGGTCCTATGCCAACAGCAGCTCAACCATCCACTACTGGAATTCGGAAACAG
TGGCACGAAGATATTACTCAGGATCTTCGAAATCATCTTGTTCACAAACTCGTCCAAGCCATATTTCCTACGCCGGATCCTGCTGCTTTA
AAAGACAGACGGATGGAAAACCTAGTTGCATATGCTCGGAAAGTTGAAGGGGACATGTATGAATCTGCAAACAATCGAGCGGAATACTAC
CACCTTCTAGCTGAGAAAATCTATAAGATCCAGAAAGAACTAGAAGAAAAACGAAGGACCAGACTACAGAAGCAGAACATGCTACCAAAT
GCTGCAGGCATGGTTCCAGTTTCCATGAATCCAGGGCCTAACATGGGACAGCCGCAACCAGGAATGACTTCTAATGGCCCTCTACCTGAC
CCAAGTATGATCCGTGGCAGTGTGCCAAACCAGATGATGCCTCGAATAACTCCACAATCTGGTTTGAATCAATTTGGCCAGATGAGCATG
GCCCAGCCCCCTATTGTACCCCGGCAAACCCCTCCTCTTCAGCACCATGGACAGTTGGCTCAACCTGGAGCTCTCAACCCGCCTATGGGC
TATGGGCCTCGTATGCAACAGCCTTCCAACCAGGGCCAGTTCCTTCCTCAGACTCAGTTCCCATCACAGGGAATGAATGTAACAAATATC
CCTTTGGCTCCGTCCAGCGGTCAAGCTCCAGTGTCTCAAGCACAAATGTCTAGTTCTTCCTGCCCGGTGAACTCTCCTATAATGCCTCCA
GGGTCTCAGGGGAGCCACATTCACTGTCCCCAGCTTCCTCAACCAGCTCTTCATCAGAATTCACCCTCGCCTGTACCTAGTCGTACCCCC
ACCCCTCACCATACTCCCCCAAGCATAGGGGCTCAGCAGCCACCAGCAACAACAATTCCAGCCCCTGTTCCTACACCTCCTGCCATGCCA
CCTGGGCCACAGTCCCAGGCTCTACATCCCCCTCCAAGGCAGACACCTACACCACCAACAACACAACTTCCCCAACAAGTGCAGCCTTCA
CTTCCTGCTGCACCTTCTGCTGACCAGCCCCAGCAGCAGCCTCGCTCACAGCAGAGCACAGCAGCGTCTGTTCCTACCCCAACAGCACCG
CTGCTTCCTCCGCAGCCTGCAACTCCACTTTCCCAGCCAGCTGTAAGCATTGAAGGACAGGTATCAAATCCTCCATCTACTAGTAGCACA
GAAGTGAATTCTCAGGCCATTGCTGAGAAGCAGCCTTCCCAGGAAGTGAAGATGGAGGCCAAAATGGAAGTGGATCAACCAGAACCAGCA
GATACTCAGCCGGAGGATATTTCAGAGTCTAAAGTGGAAGACTGTAAAATGGAATCTACCGAAACAGAAGAGAGAAGCACTGAGTTAAAA
ACTGAAATAAAAGAGGAGGAAGACCAGCCAAGTACTTCAGCTACCCAGTCATCTCCGGCTCCAGGACAGTCAAAGAAAAAGATTTTCAAA
CCAGAAGAACTACGACAGGCACTGATGCCAACTTTGGAGGCACTTTACCGTCAGGATCCAGAATCCCTTCCCTTTCGTCAACCTGTGGAC
CCTCAGCTTTTAGGAATCCCTGATTACTTTGATATTGTGAAGAGCCCCATGGATCTTTCTACCATTAAGAGGAAGTTAGACACTGGACAG
TATCAGGAGCCCTGGCAGTATGTCGATGATATTTGGCTTATGTTCAATAATGCCTGGTTATATAACCGGAAAACATCACGGGTATACAAA
TACTGCTCCAAGCTCTCTGAGGTCTTTGAACAAGAAATTGACCCAGTGATGCAAAGCCTTGGATACTGTTGTGGCAGAAAGTTGGAGTTC
TCTCCACAGACACTGTGTTGCTACGGCAAACAGTTGTGCACAATACCTCGTGATGCCACTTATTACAGTTACCAGAACAGGTATCATTTC
TGTGAGAAGTGTTTCAATGAGATCCAAGGGGAGAGCGTTTCTTTGGGGGATGACCCTTCCCAGCCTCAAACTACAATAAATAAAGAACAA
TTTTCCAAGAGAAAAAATGACACACTGGATCCTGAACTGTTTGTTGAATGTACAGAGTGCGGAAGAAAGATGCATCAGATCTGTGTCCTT
CACCATGAGATCATCTGGCCTGCTGGATTCGTCTGTGATGGCTGTTTAAAGAAAAGTGCACGAACTAGGAAAGAAAATAAGTTTTCTGCT
AAAAGGTTGCCATCTACCAGACTTGGCACCTTTCTAGAGAATCGTGTGAATGACTTTCTGAGGCGACAGAATCACCCTGAGTCAGGAGAG
GTCACTGTTAGAGTAGTTCATGCTTCTGACAAAACCGTGGAAGTAAAACCAGGCATGAAAGCAAGGTTTGTGGACAGTGGAGAGATGGCA
GAATCCTTTCCATACCGAACCAAAGCCCTCTTTGCCTTTGAAGAAATTGATGGTGTTGACCTGTGCTTCTTTGGCATGCATGTTCAAGAG
TATGGCTCTGACTGCCCTCCACCCAACCAGAGGAGAGTATACATATCTTACCTCGATAGTGTTCATTTCTTCCGTCCTAAATGCTTGAGG
ACTGCAGTCTATCATGAAATCCTAATTGGATATTTAGAATATGTCAAGAAATTAGGTTACACAACAGGGCATATTTGGGCATGTCCACCA
AGTGAGGGAGATGATTATATCTTCCATTGCCATCCTCCTGACCAGAAGATACCCAAGCCCAAGCGACTGCAGGAATGGTACAAAAAAATG
CTTGACAAGGCTGTATCAGAGCGTATTGTCCATGACTACAAGGATATTTTTAAACAAGCTACTGAAGATAGATTAACAAGTGCAAAGGAA
TTGCCTTATTTCGAGGGTGATTTCTGGCCCAATGTTCTGGAAGAAAGCATTAAGGAACTGGAACAGGAGGAAGAAGAGAGAAAACGAGAG
GAAAACACCAGCAATGAAAGCACAGATGTGACCAAGGGAGACAGCAAAAATGCTAAAAAGAAGAATAATAAGAAAACCAGCAAAAATAAG
AGCAGCCTGAGTAGGGGCAACAAGAAGAAACCCGGGATGCCCAATGTATCTAACGACCTCTCACAGAAACTATATGCCACCATGGAGAAG
CATAAAGAGGTCTTCTTTGTGATCCGCCTCATTGCTGGCCCTGCTGCCAACTCCCTGCCTCCCATTGTTGATCCTGATCCTCTCATCCCC
TGCGATCTGATGGATGGTCGGGATGCGTTTCTCACGCTGGCAAGGGACAAGCACCTGGAGTTCTCTTCACTCCGAAGAGCCCAGTGGTCC
ACCATGTGCATGCTGGTGGAGCTGCACACGCAGAGCCAGGACCGCTTTGTCTACACCTGCAATGAATGCAAGCACCATGTGGAGACACGC
TGGCACTGTACTGTCTGTGAGCGTGCAATGATGCGCTTCTCAGAGTTGGAGATGAAAGAAAGAGAAGGTGGCCACCCAGCAACCAAAGAC
TCCGAGATGTGCAAATTCAGCCCAGCCGACTGGGAAAGGTTGAAAGGAAATCAGGACAAAAAGCCAAAGTCGGTCACCCTGGAGGAGGCC
ATTGCAGAACAGAACGAAAGTGAGAGATGCGAGTATAGTGTTGGAAACAAGCACCGTGATCCCTTTGAAGCCCCAGAGGACAAAGATCTT
CCTGTGGAGAAGTACTTTGTGGAGAGGCAGCCTGTGAGCGAGCCTCCCGCAGACCAGGTGGCCTCGGACATGCCTCACAGCCCCACCCTC
CGGGTGGACAGGAAACGCAAAGTCTCAGGTGACAGCAGCCACACTGAGACCACTGCGGAGGAGGTGCCAGAGGACCCTCTGCTGAAAGCC
AAACGCCGACGAGTCTCTAAAGGGCTCCATCCTAAAAAACAACGCCACTTGCTGCACCTTAGAGAACGATGGGAGCAGCAGGTGTCGGCA
GCAGATGGCAAACCTGGCCGGCAAAGCAGGAAGGAAGTGACCCAGGCCACTCAGCCTGAGGCCATTCCTCAGGGGACTAACATCACTGAA
GAGAAACCTGGCAGGAAAAGGGCAGAGGCCAAAGGCAACAGAAGCTGGTCGGAAGAGTCTCTTAAACCCAGTGACAATGAACAAGGCTTG
CCTGTGTTCTCCGGCTCTCCGCCCATGAAGAGTCTTTCATCCACCAGTGCAGGCGGCAAAAAGCAGGCTCAGCCAAGCTGCGCACCAGCC
TCCAGGCCGCCTGCCAAACAGCAGAAAATTAAAGAAAACCAGAAGACAGATGTGCTGTGTGCAGACGAAGAAGAGGATTGCCAGGCTGCC
TCCCTGCTGCAGAAATACACCGACAACAGCGAGAAGCCATCCGGGAAGAGACTGTGCAAAACCAAACACTTGATCCCTCAGGAGTCCAGG
CGGGGATTGCCACTGACAGGGGAATACTACGTGGAGAATGCCGATGGCAAGGTGACTGTCCGGAGATTCAGAAAGCGGCCGGAGCCCAGT
TCGGACTATGATCTGTCACCAGCCAAGCAGGAGCCAAAGCCCTTCGACCGCTTGCAGCAACTGCTACCAGCCTCCCAGTCCACACAGCTG
CCATGCTCAAGTTCCCCTCAGGAGACCACCCAGTCTCGCCCTATGCCGCCGGAAGCACGGAGACTTATTGTCAATAAGAACGCTGGCGAG
ACCCTTCTGCAGCGGGCAGCCAGGCTTGGCTATGAGGAAGTGGTCCTGTACTGCTTAGAGAACAAGATTTGTGATGTAAATCATCGGGAC
AACGCAGGTTACTGCGCCCTGCATGAAGCTTGTGCTAGGGGCTGGCTCAACATTGTGCGACACCTCCTTGAATATGGCGCTGATGTCAAC
TGTAGTGCCCAGGATGGAACCAGGCCTCTGCACGATGCTGTTGAGAACGATCACTTGGAAATTGTCCGACTACTTCTCTCTTATGGTGCT
GACCCCACCTTGGCTACGTACTCAGGTAGAACCATCATGAAAATGACCCACAGTGAACTTATGGAAAAGTTCTTAACAGATTATTTAAAT
GACCTCCAGGGTCGCAATGATGATGACGCCAGTGGCACTTGGGACTTCTATGGCAGCTCTGTTTGTGAACCAGATGATGAAAGTGGCTAT
GATGTTTTAGCCAACCCCCCAGGACCAGAAGACCAGGATGATGATGACGATGCCTATAGCGATGTGTTTGAATTTGAATTTTCAGAGACC
CCCCTCTTACCGTGTTATAACATCCAAGTATCTGTGGCTCAGGGGCCACGAAACTGGCTACTGCTTTCGGATGTCCTTAAGAAATTGAAA
ATGTCCTCCCGCATATTTCGCTGCAATTTTCCAAACGTGGAAATTGTCACCATTGCAGAGGCAGAATTTTATCGGCAGGTTTCTGCAAGT
CTCTTGTTCTCTTGCTCCAAAGACCTGGAAGCCTTCAACCCTGAAAGTAAGGAGCTGTTAGATCTGGTGGAATTCACGAACGAAATTCAG

>In-frame_EP300_ENST00000263253_chr22_41572532_+_BCOR_ENST00000342274_chrX_39930412_-_7176nt
ATGGCCGAGAATGTGGTGGAACCGGGGCCGCCTTCAGCCAAGCGGCCTAAACTCTCATCTCCGGCCCTCTCGGCGTCCGCCAGCGATGGC
ACAGATTTTGGCTCTCTATTTGACTTGGAGCACGACTTACCAGATGAATTAATCAACTCTACAGAATTGGGACTAACCAATGGTGGTGAT
ATTAATCAGCTTCAGACAAGTCTTGGCATGGTACAAGATGCAGCTTCTAAACATAAACAGCTGTCAGAATTGCTGCGATCTGGTAGTTCC
CCTAACCTCAATATGGGAGTTGGTGGCCCAGGTCAAGTCATGGCCAGCCAGGCCCAACAGAGCAGTCCTGGATTAGGTTTGATAAATAGC
ATGGTCAAAAGCCCAATGACACAGGCAGGCTTGACTTCTCCCAACATGGGGATGGGCACTAGTGGACCAAATCAGGGTCCTACGCAGTCA
ACAGGTATGATGAACAGTCCAGTAAATCAGCCTGCCATGGGAATGAACACAGGGATGAATGCGGGCATGAATCCTGGAATGTTGGCTGCA
GGCAATGGACAAGGGATAATGCCTAATCAAGTCATGAACGGTTCAATTGGAGCAGGCCGAGGGCGACAGAATATGCAGTACCCAAACCCA
GGCATGGGAAGTGCTGGCAACTTACTGACTGAGCCTCTTCAGCAGGGCTCTCCCCAGATGGGAGGACAAACAGGATTGAGAGGCCCCCAG
CCTCTTAAGATGGGAATGATGAACAACCCCAATCCTTATGGTTCACCATATACTCAGAATCCTGGACAGCAGATTGGAGCCAGTGGCCTT
GGTCTCCAGATTCAGACAAAAACTGTACTATCAAATAACTTATCTCCATTTGCTATGGACAAAAAGGCAGTTCCTGGTGGAGGAATGCCC
AACATGGGTCAACAGCCAGCCCCGCAGGTCCAGCAGCCAGGCCTGGTGACTCCAGTTGCCCAAGGGATGGGTTCTGGAGCACATACAGCT
GATCCAGAGAAGCGCAAGCTCATCCAGCAGCAGCTTGTTCTCCTTTTGCATGCTCACAAGTGCCAGCGCCGGGAACAGGCCAATGGGGAA
GTGAGGCAGTGCAACCTTCCCCACTGTCGCACAATGAAGAATGTCCTAAACCACATGACACACTGCCAGTCAGGCAAGTCTTGCCAAGTG
GCACACTGTGCATCTTCTCGACAAATCATTTCACACTGGAAGAATTGTACAAGACATGATTGTCCTGTGTGTCTCCCCCTCAAAAATGCT
GGTGATAAGAGAAATCAACAGCCAATTTTGACTGGAGCACCCGTTGGACTTGGAAATCCTAGCTCTCTAGGGGTGGGTCAACAGTCTGCC
CCCAACCTAAGCACTGTTAGTCAGATTGATCCCAGCTCCATAGAAAGAGCCTATGCAGCTCTTGGACTACCCTATCAAGTAAATCAGATG
CCGACACAACCCCAGGTGCAAGCAAAGAACCAGCAGAATCAGCAGCCTGGGCAGTCTCCCCAAGGCATGCGGCCCATGAGCAACATGAGT
GCTAGTCCTATGGGAGTAAATGGAGGTGTAGGAGTTCAAACGCCGAGTCTTCTTTCTGACTCAATGTTGCATTCAGCCATAAATTCTCAA
AACCCAATGATGAGTGAAAATGCCAGTGTGCCCTCCCTGGGTCCTATGCCAACAGCAGCTCAACCATCCACTACTGGAATTCGGAAACAG
TGGCACGAAGATATTACTCAGGATCTTCGAAATCATCTTGTTCACAAACTCGTCCAAGCCATATTTCCTACGCCGGATCCTGCTGCTTTA
AAAGACAGACGGATGGAAAACCTAGTTGCATATGCTCGGAAAGTTGAAGGGGACATGTATGAATCTGCAAACAATCGAGCGGAATACTAC
CACCTTCTAGCTGAGAAAATCTATAAGATCCAGAAAGAACTAGAAGAAAAACGAAGGACCAGACTACAGAAGCAGAACATGCTACCAAAT
GCTGCAGGCATGGTTCCAGTTTCCATGAATCCAGGGCCTAACATGGGACAGCCGCAACCAGGAATGACTTCTAATGGCCCTCTACCTGAC
CCAAGTATGATCCGTGGCAGTGTGCCAAACCAGATGATGCCTCGAATAACTCCACAATCTGGTTTGAATCAATTTGGCCAGATGAGCATG
GCCCAGCCCCCTATTGTACCCCGGCAAACCCCTCCTCTTCAGCACCATGGACAGTTGGCTCAACCTGGAGCTCTCAACCCGCCTATGGGC
TATGGGCCTCGTATGCAACAGCCTTCCAACCAGGGCCAGTTCCTTCCTCAGACTCAGTTCCCATCACAGGGAATGAATGTAACAAATATC
CCTTTGGCTCCGTCCAGCGGTCAAGCTCCAGTGTCTCAAGCACAAATGTCTAGTTCTTCCTGCCCGGTGAACTCTCCTATAATGCCTCCA
GGGTCTCAGGGGAGCCACATTCACTGTCCCCAGCTTCCTCAACCAGCTCTTCATCAGAATTCACCCTCGCCTGTACCTAGTCGTACCCCC
ACCCCTCACCATACTCCCCCAAGCATAGGGGCTCAGCAGCCACCAGCAACAACAATTCCAGCCCCTGTTCCTACACCTCCTGCCATGCCA
CCTGGGCCACAGTCCCAGGCTCTACATCCCCCTCCAAGGCAGACACCTACACCACCAACAACACAACTTCCCCAACAAGTGCAGCCTTCA
CTTCCTGCTGCACCTTCTGCTGACCAGCCCCAGCAGCAGCCTCGCTCACAGCAGAGCACAGCAGCGTCTGTTCCTACCCCAACAGCACCG
CTGCTTCCTCCGCAGCCTGCAACTCCACTTTCCCAGCCAGCTGTAAGCATTGAAGGACAGGTATCAAATCCTCCATCTACTAGTAGCACA
GAAGTGAATTCTCAGGCCATTGCTGAGAAGCAGCCTTCCCAGGAAGTGAAGATGGAGGCCAAAATGGAAGTGGATCAACCAGAACCAGCA
GATACTCAGCCGGAGGATATTTCAGAGTCTAAAGTGGAAGACTGTAAAATGGAATCTACCGAAACAGAAGAGAGAAGCACTGAGTTAAAA
ACTGAAATAAAAGAGGAGGAAGACCAGCCAAGTACTTCAGCTACCCAGTCATCTCCGGCTCCAGGACAGTCAAAGAAAAAGATTTTCAAA
CCAGAAGAACTACGACAGGCACTGATGCCAACTTTGGAGGCACTTTACCGTCAGGATCCAGAATCCCTTCCCTTTCGTCAACCTGTGGAC
CCTCAGCTTTTAGGAATCCCTGATTACTTTGATATTGTGAAGAGCCCCATGGATCTTTCTACCATTAAGAGGAAGTTAGACACTGGACAG
TATCAGGAGCCCTGGCAGTATGTCGATGATATTTGGCTTATGTTCAATAATGCCTGGTTATATAACCGGAAAACATCACGGGTATACAAA
TACTGCTCCAAGCTCTCTGAGGTCTTTGAACAAGAAATTGACCCAGTGATGCAAAGCCTTGGATACTGTTGTGGCAGAAAGTTGGAGTTC
TCTCCACAGACACTGTGTTGCTACGGCAAACAGTTGTGCACAATACCTCGTGATGCCACTTATTACAGTTACCAGAACAGGTATCATTTC
TGTGAGAAGTGTTTCAATGAGATCCAAGGGGAGAGCGTTTCTTTGGGGGATGACCCTTCCCAGCCTCAAACTACAATAAATAAAGAACAA
TTTTCCAAGAGAAAAAATGACACACTGGATCCTGAACTGTTTGTTGAATGTACAGAGTGCGGAAGAAAGATGCATCAGATCTGTGTCCTT
CACCATGAGATCATCTGGCCTGCTGGATTCGTCTGTGATGGCTGTTTAAAGAAAAGTGCACGAACTAGGAAAGAAAATAAGTTTTCTGCT
AAAAGGTTGCCATCTACCAGACTTGGCACCTTTCTAGAGAATCGTGTGAATGACTTTCTGAGGCGACAGAATCACCCTGAGTCAGGAGAG
GTCACTGTTAGAGTAGTTCATGCTTCTGACAAAACCGTGGAAGTAAAACCAGGCATGAAAGCAAGGTTTGTGGACAGTGGAGAGATGGCA
GAATCCTTTCCATACCGAACCAAAGCCCTCTTTGCCTTTGAAGAAATTGATGGTGTTGACCTGTGCTTCTTTGGCATGCATGTTCAAGAG
TATGGCTCTGACTGCCCTCCACCCAACCAGAGGAGAGTATACATATCTTACCTCGATAGTGTTCATTTCTTCCGTCCTAAATGCTTGAGG
ACTGCAGTCTATCATGAAATCCTAATTGGATATTTAGAATATGTCAAGAAATTAGGTTACACAACAGGGCATATTTGGGCATGTCCACCA
AGTGAGGGAGATGATTATATCTTCCATTGCCATCCTCCTGACCAGAAGATACCCAAGCCCAAGCGACTGCAGGAATGGTACAAAAAAATG
CTTGACAAGGCTGTATCAGAGCGTATTGTCCATGACTACAAGGATATTTTTAAACAAGCTACTGAAGATAGATTAACAAGTGCAAAGGAA
TTGCCTTATTTCGAGGGTGATTTCTGGCCCAATGTTCTGGAAGAAAGCATTAAGGAACTGGAACAGGAGGAAGAAGAGAGAAAACGAGAG
GAAAACACCAGCAATGAAAGCACAGATGTGACCAAGGGAGACAGCAAAAATGCTAAAAAGAAGAATAATAAGAAAACCAGCAAAAATAAG
AGCAGCCTGAGTAGGGGCAACAAGAAGAAACCCGGGATGCCCAATGTATCTAACGACCTCTCACAGAAACTATATGCCACCATGGAGAAG
CATAAAGAGGTCTTCTTTGTGATCCGCCTCATTGCTGGCCCTGCTGCCAACTCCCTGCCTCCCATTGTTGATCCTGATCCTCTCATCCCC
TGCGATCTGATGGATGGTCGGGATGCGTTTCTCACGCTGGCAAGGGACAAGCACCTGGAGTTCTCTTCACTCCGAAGAGCCCAGTGGTCC
ACCATGTGCATGCTGGTGGAGCTGCACACGCAGAGCCAGGACCGCTTTGTCTACACCTGCAATGAATGCAAGCACCATGTGGAGACACGC
TGGCACTGTACTGTCTGTGAGCGTGCAATGATGCGCTTCTCAGAGTTGGAGATGAAAGAAAGAGAAGGTGGCCACCCAGCAACCAAAGAC
TCCGAGATGTGCAAATTCAGCCCAGCCGACTGGGAAAGGTTGAAAGGAAATCAGGACAAAAAGCCAAAGTCGGTCACCCTGGAGGAGGCC
ATTGCAGAACAGAACGAAAGTGAGAGATGCGAGTATAGTGTTGGAAACAAGCACCGTGATCCCTTTGAAGCCCCAGAGGACAAAGATCTT
CCTGTGGAGAAGTACTTTGTGGAGAGGCAGCCTGTGAGCGAGCCTCCCGCAGACCAGGTGGCCTCGGACATGCCTCACAGCCCCACCCTC
CGGGTGGACAGGAAACGCAAAGTCTCAGGTGACAGCAGCCACACTGAGACCACTGCGGAGGAGGTGCCAGAGGACCCTCTGCTGAAAGCC
AAACGCCGACGAGTCTCTAAAGGGCTCCATCCTAAAAAACAACGCCACTTGCTGCACCTTAGAGAACGATGGGAGCAGCAGGTGTCGGCA
GCAGATGGCAAACCTGGCCGGCAAAGCAGGAAGGAAGTGACCCAGGCCACTCAGCCTGAGGCCATTCCTCAGGGGACTAACATCACTGAA
GAGAAACCTGGCAGGAAAAGGGCAGAGGCCAAAGGCAACAGAAGCTGGTCGGAAGAGTCTCTTAAACCCAGTGACAATGAACAAGGCTTG
CCTGTGTTCTCCGGCTCTCCGCCCATGAAGAGTCTTTCATCCACCAGTGCAGGCGGCAAAAAGCAGGCTCAGCCAAGCTGCGCACCAGCC
TCCAGGCCGCCTGCCAAACAGCAGAAAATTAAAGAAAACCAGAAGACAGATGTGCTGTGTGCAGACGAAGAAGAGGATTGCCAGGCTGCC
TCCCTGCTGCAGAAATACACCGACAACAGCGAGAAGCCATCCGGGAAGAGACTGTGCAAAACCAAACACTTGATCCCTCAGGAGTCCAGG
CGGGGATTGCCACTGACAGGGGAATACTACGTGGAGAATGCCGATGGCAAGGTGACTGTCCGGAGATTCAGAAAGCGGCCGGAGCCCAGT
TCGGACTATGATCTGTCACCAGCCAAGCAGGAGCCAAAGCCCTTCGACCGCTTGCAGCAACTGCTACCAGCCTCCCAGTCCACACAGCTG
CCATGCTCAAGTTCCCCTCAGGAGACCACCCAGTCTCGCCCTATGCCGCCGGAAGCACGGAGACTTATTGTCAATAAGAACGCTGGCGAG
ACCCTTCTGCAGCGGGCAGCCAGGCTTGGCTATGAGGAAGTGGTCCTGTACTGCTTAGAGAACAAGATTTGTGATGTAAATCATCGGGAC
AACGCAGGTTACTGCGCCCTGCATGAAGCTTGTGCTAGGGGCTGGCTCAACATTGTGCGACACCTCCTTGAATATGGCGCTGATGTCAAC
TGTAGTGCCCAGGATGGAACCAGGCCTCTGCACGATGCTGTTGAGAACGATCACTTGGAAATTGTCCGACTACTTCTCTCTTATGGTGCT
GACCCCACCTTGGCTACGTACTCAGGTAGAACCATCATGAAAATGACCCACAGTGAACTTATGGAAAAGTTCTTAACAGATTATTTAAAT
GACCTCCAGGGTCGCAATGATGATGACGCCAGTGGCACTTGGGACTTCTATGGCAGCTCTGTTTGTGAACCAGATGATGAAAGTGGCTAT
GATGTTTTAGCCAACCCCCCAGGACCAGAAGACCAGGATGATGATGACGATGCCTATAGCGATGTGTTTGAATTTGAATTTTCAGAGACC
CCCCTCTTACCGTGTTATAACATCCAAGTATCTGTGGCTCAGGGGCCACGAAACTGGCTACTGCTTTCGGATGTCCTTAAGAAATTGAAA
ATGTCCTCCCGCATATTTCGCTGCAATTTTCCAAACGTGGAAATTGTCACCATTGCAGAGGCAGAATTTTATCGGCAGGTTTCTGCAAGT
CTCTTGTTCTCTTGCTCCAAAGACCTGGAAGCCTTCAACCCTGAAAGTAAGGAGCTGTTAGATCTGGTGGAATTCACGAACGAAATTCAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_EP300_ENST00000263253_chr22_41572532_+_BCOR_ENST00000378455_chrX_39930412_-_9258nt
CTTGTTTGTGTGCTAGGCTGGGGGGGAGAGAGGGCGAGAGAGAGCGGGCGAGAGTGGGCAAGCAGGACGCCGGGCTGAGTGCTAACTGCG
GGAGCCAGAGAGTGCGGAGGGGAGTCGGGTCGGAGAGAGGCGGCAGGGGCCGAGACAGTGGCAGGGGGCCCGGGGCGCACGGGCTGAGGC
GACCCCCAGCCCCCTCCCGTCCGCACACACCCCCACCGCGGTCCAGCAGCCGGGCCGGCGTCGACGCCTAGGGGGGACCATTACATAACC
CCGCGCCCCGCGGCGTCTTCTCCCGCCGCCGCGGGCGGCCCCGAACGGAGCCCCGGGGGGCGGGCGCTCCCAGCACCTGGCCGCCGGCGG
TGGGGGCCGTAGCAGCGGCCGTATTTATTTATTTTCCGCGGGAAAGGAAGGCGAAGGAGGGGAGCGCGGCGCGAGGAGGGGCCGCCTGCG
CCGCCGCCGGAGCGGGGCCTCCTCGGTGGGCTCCGCGTCGGCGCGGGCGTGCGGGCGGCGCTGCTCGGCCCGGCCCCCTCGGCCCTCTGG
TCCGGCCAGCTCCGCTCCCGGCGTCCTTGCCGCGCCTCCGCCGGCCGCCGCGCGATGTGAGGCGGCGGCGCCAGCCTGGCTCTCGGCTCG
GGCGAGTTCTCTGCGGCCATTAGGGGCCGGTGCGGCGGCGGCGGCGCGGAGCGCGGCGGCAGGAGGAGGGTTCGGAGGGTGGGGGCGCAG
GCCCGGGAGGGGGCACCGGGAGGAGGTGAGTGTCTCTTGTCGCCTCCTCCTCTCCCCCCTTTTCGCCCCCGCCTCCTTGTGGCGATGAGA
AGGAGGAGGACAGCGCCGAGGAGGAAGAGGTTGATGGCGGCGGCGGAGCTCCGAGAGACCTCGGCTGGGCAGGGGCCGGCCGTGGCGGGC
CGGGGACTGCGCCTCTAGAGCCGCGAGTTCTCGGGAATTCGCCGCAGCGGACGCGCTCGGCGAATTTGTGCTCTTGTGCCCTCCTCCGGG
CTTGGGCCCAGGCCCGGCCCCTCGCACTTGCCCTTACCTTTTCTATCGAGTCCGCATCCCTCTCCAGCCACTGCGACCCGGCGAAGAGAA
AAAGGAACTTCCCCCACCCCCTCGGGTGCCGTCGGAGCCCCCCAGCCCACCCCTGGGTGCGGCGCGGGGACCCCGGGCCGAAGAAGAGAT
TTCCTGAGGATTCTGGTTTTCCTCGCTTGTATCTCCGAAAGAATTAAAAATGGCCGAGAATGTGGTGGAACCGGGGCCGCCTTCAGCCAA
GCGGCCTAAACTCTCATCTCCGGCCCTCTCGGCGTCCGCCAGCGATGGCACAGATTTTGGCTCTCTATTTGACTTGGAGCACGACTTACC
AGATGAATTAATCAACTCTACAGAATTGGGACTAACCAATGGTGGTGATATTAATCAGCTTCAGACAAGTCTTGGCATGGTACAAGATGC
AGCTTCTAAACATAAACAGCTGTCAGAATTGCTGCGATCTGGTAGTTCCCCTAACCTCAATATGGGAGTTGGTGGCCCAGGTCAAGTCAT
GGCCAGCCAGGCCCAACAGAGCAGTCCTGGATTAGGTTTGATAAATAGCATGGTCAAAAGCCCAATGACACAGGCAGGCTTGACTTCTCC
CAACATGGGGATGGGCACTAGTGGACCAAATCAGGGTCCTACGCAGTCAACAGGTATGATGAACAGTCCAGTAAATCAGCCTGCCATGGG
AATGAACACAGGGATGAATGCGGGCATGAATCCTGGAATGTTGGCTGCAGGCAATGGACAAGGGATAATGCCTAATCAAGTCATGAACGG
TTCAATTGGAGCAGGCCGAGGGCGACAGAATATGCAGTACCCAAACCCAGGCATGGGAAGTGCTGGCAACTTACTGACTGAGCCTCTTCA
GCAGGGCTCTCCCCAGATGGGAGGACAAACAGGATTGAGAGGCCCCCAGCCTCTTAAGATGGGAATGATGAACAACCCCAATCCTTATGG
TTCACCATATACTCAGAATCCTGGACAGCAGATTGGAGCCAGTGGCCTTGGTCTCCAGATTCAGACAAAAACTGTACTATCAAATAACTT
ATCTCCATTTGCTATGGACAAAAAGGCAGTTCCTGGTGGAGGAATGCCCAACATGGGTCAACAGCCAGCCCCGCAGGTCCAGCAGCCAGG
CCTGGTGACTCCAGTTGCCCAAGGGATGGGTTCTGGAGCACATACAGCTGATCCAGAGAAGCGCAAGCTCATCCAGCAGCAGCTTGTTCT
CCTTTTGCATGCTCACAAGTGCCAGCGCCGGGAACAGGCCAATGGGGAAGTGAGGCAGTGCAACCTTCCCCACTGTCGCACAATGAAGAA
TGTCCTAAACCACATGACACACTGCCAGTCAGGCAAGTCTTGCCAAGTGGCACACTGTGCATCTTCTCGACAAATCATTTCACACTGGAA
GAATTGTACAAGACATGATTGTCCTGTGTGTCTCCCCCTCAAAAATGCTGGTGATAAGAGAAATCAACAGCCAATTTTGACTGGAGCACC
CGTTGGACTTGGAAATCCTAGCTCTCTAGGGGTGGGTCAACAGTCTGCCCCCAACCTAAGCACTGTTAGTCAGATTGATCCCAGCTCCAT
AGAAAGAGCCTATGCAGCTCTTGGACTACCCTATCAAGTAAATCAGATGCCGACACAACCCCAGGTGCAAGCAAAGAACCAGCAGAATCA
GCAGCCTGGGCAGTCTCCCCAAGGCATGCGGCCCATGAGCAACATGAGTGCTAGTCCTATGGGAGTAAATGGAGGTGTAGGAGTTCAAAC
GCCGAGTCTTCTTTCTGACTCAATGTTGCATTCAGCCATAAATTCTCAAAACCCAATGATGAGTGAAAATGCCAGTGTGCCCTCCCTGGG
TCCTATGCCAACAGCAGCTCAACCATCCACTACTGGAATTCGGAAACAGTGGCACGAAGATATTACTCAGGATCTTCGAAATCATCTTGT
TCACAAACTCGTCCAAGCCATATTTCCTACGCCGGATCCTGCTGCTTTAAAAGACAGACGGATGGAAAACCTAGTTGCATATGCTCGGAA
AGTTGAAGGGGACATGTATGAATCTGCAAACAATCGAGCGGAATACTACCACCTTCTAGCTGAGAAAATCTATAAGATCCAGAAAGAACT
AGAAGAAAAACGAAGGACCAGACTACAGAAGCAGAACATGCTACCAAATGCTGCAGGCATGGTTCCAGTTTCCATGAATCCAGGGCCTAA
CATGGGACAGCCGCAACCAGGAATGACTTCTAATGGCCCTCTACCTGACCCAAGTATGATCCGTGGCAGTGTGCCAAACCAGATGATGCC
TCGAATAACTCCACAATCTGGTTTGAATCAATTTGGCCAGATGAGCATGGCCCAGCCCCCTATTGTACCCCGGCAAACCCCTCCTCTTCA
GCACCATGGACAGTTGGCTCAACCTGGAGCTCTCAACCCGCCTATGGGCTATGGGCCTCGTATGCAACAGCCTTCCAACCAGGGCCAGTT
CCTTCCTCAGACTCAGTTCCCATCACAGGGAATGAATGTAACAAATATCCCTTTGGCTCCGTCCAGCGGTCAAGCTCCAGTGTCTCAAGC
ACAAATGTCTAGTTCTTCCTGCCCGGTGAACTCTCCTATAATGCCTCCAGGGTCTCAGGGGAGCCACATTCACTGTCCCCAGCTTCCTCA
ACCAGCTCTTCATCAGAATTCACCCTCGCCTGTACCTAGTCGTACCCCCACCCCTCACCATACTCCCCCAAGCATAGGGGCTCAGCAGCC
ACCAGCAACAACAATTCCAGCCCCTGTTCCTACACCTCCTGCCATGCCACCTGGGCCACAGTCCCAGGCTCTACATCCCCCTCCAAGGCA
GACACCTACACCACCAACAACACAACTTCCCCAACAAGTGCAGCCTTCACTTCCTGCTGCACCTTCTGCTGACCAGCCCCAGCAGCAGCC
TCGCTCACAGCAGAGCACAGCAGCGTCTGTTCCTACCCCAACAGCACCGCTGCTTCCTCCGCAGCCTGCAACTCCACTTTCCCAGCCAGC
TGTAAGCATTGAAGGACAGGTATCAAATCCTCCATCTACTAGTAGCACAGAAGTGAATTCTCAGGCCATTGCTGAGAAGCAGCCTTCCCA
GGAAGTGAAGATGGAGGCCAAAATGGAAGTGGATCAACCAGAACCAGCAGATACTCAGCCGGAGGATATTTCAGAGTCTAAAGTGGAAGA
CTGTAAAATGGAATCTACCGAAACAGAAGAGAGAAGCACTGAGTTAAAAACTGAAATAAAAGAGGAGGAAGACCAGCCAAGTACTTCAGC
TACCCAGTCATCTCCGGCTCCAGGACAGTCAAAGAAAAAGATTTTCAAACCAGAAGAACTACGACAGGCACTGATGCCAACTTTGGAGGC
ACTTTACCGTCAGGATCCAGAATCCCTTCCCTTTCGTCAACCTGTGGACCCTCAGCTTTTAGGAATCCCTGATTACTTTGATATTGTGAA
GAGCCCCATGGATCTTTCTACCATTAAGAGGAAGTTAGACACTGGACAGTATCAGGAGCCCTGGCAGTATGTCGATGATATTTGGCTTAT
GTTCAATAATGCCTGGTTATATAACCGGAAAACATCACGGGTATACAAATACTGCTCCAAGCTCTCTGAGGTCTTTGAACAAGAAATTGA
CCCAGTGATGCAAAGCCTTGGATACTGTTGTGGCAGAAAGTTGGAGTTCTCTCCACAGACACTGTGTTGCTACGGCAAACAGTTGTGCAC
AATACCTCGTGATGCCACTTATTACAGTTACCAGAACAGGTATCATTTCTGTGAGAAGTGTTTCAATGAGATCCAAGGGGAGAGCGTTTC
TTTGGGGGATGACCCTTCCCAGCCTCAAACTACAATAAATAAAGAACAATTTTCCAAGAGAAAAAATGACACACTGGATCCTGAACTGTT
TGTTGAATGTACAGAGTGCGGAAGAAAGATGCATCAGATCTGTGTCCTTCACCATGAGATCATCTGGCCTGCTGGATTCGTCTGTGATGG
CTGTTTAAAGAAAAGTGCACGAACTAGGAAAGAAAATAAGTTTTCTGCTAAAAGGTTGCCATCTACCAGACTTGGCACCTTTCTAGAGAA
TCGTGTGAATGACTTTCTGAGGCGACAGAATCACCCTGAGTCAGGAGAGGTCACTGTTAGAGTAGTTCATGCTTCTGACAAAACCGTGGA
AGTAAAACCAGGCATGAAAGCAAGGTTTGTGGACAGTGGAGAGATGGCAGAATCCTTTCCATACCGAACCAAAGCCCTCTTTGCCTTTGA
AGAAATTGATGGTGTTGACCTGTGCTTCTTTGGCATGCATGTTCAAGAGTATGGCTCTGACTGCCCTCCACCCAACCAGAGGAGAGTATA
CATATCTTACCTCGATAGTGTTCATTTCTTCCGTCCTAAATGCTTGAGGACTGCAGTCTATCATGAAATCCTAATTGGATATTTAGAATA
TGTCAAGAAATTAGGTTACACAACAGGGCATATTTGGGCATGTCCACCAAGTGAGGGAGATGATTATATCTTCCATTGCCATCCTCCTGA
CCAGAAGATACCCAAGCCCAAGCGACTGCAGGAATGGTACAAAAAAATGCTTGACAAGGCTGTATCAGAGCGTATTGTCCATGACTACAA
GGATATTTTTAAACAAGCTACTGAAGATAGATTAACAAGTGCAAAGGAATTGCCTTATTTCGAGGGTGATTTCTGGCCCAATGTTCTGGA
AGAAAGCATTAAGGAACTGGAACAGGAGGAAGAAGAGAGAAAACGAGAGGAAAACACCAGCAATGAAAGCACAGATGTGACCAAGGGAGA
CAGCAAAAATGCTAAAAAGAAGAATAATAAGAAAACCAGCAAAAATAAGAGCAGCCTGAGTAGGGGCAACAAGAAGAAACCCGGGATGCC
CAATGTATCTAACGACCTCTCACAGAAACTATATGCCACCATGGAGAAGCATAAAGAGGTCTTCTTTGTGATCCGCCTCATTGCTGGCCC
TGCTGCCAACTCCCTGCCTCCCATTGTTGATCCTGATCCTCTCATCCCCTGCGATCTGATGGATGGTCGGGATGCGTTTCTCACGCTGGC
AAGGGACAAGCACCTGGAGTTCTCTTCACTCCGAAGAGCCCAGTGGTCCACCATGTGCATGCTGGTGGAGCTGCACACGCAGAGCCAGGA
CCGCTTTGTCTACACCTGCAATGAATGCAAGCACCATGTGGAGACACGCTGGCACTGTACTGTCTGTGAGCGTGCAATGATGCGCTTCTC
AGAGTTGGAGATGAAAGAAAGAGAAGGTGGCCACCCAGCAACCAAAGACTCCGAGATGTGCAAATTCAGCCCAGCCGACTGGGAAAGGTT
GAAAGGAAATCAGGACAAAAAGCCAAAGTCGGTCACCCTGGAGGAGGCCATTGCAGAACAGAACGAAAGTGAGAGATGCGAGTATAGTGT
TGGAAACAAGCACCGTGATCCCTTTGAAGCCCCAGAGGACAAAGATCTTCCTGTGGAGAAGTACTTTGTGGAGAGGCAGCCTGTGAGCGA
GCCTCCCGCAGACCAGGTGGCCTCGGACATGCCTCACAGCCCCACCCTCCGGGTGGACAGGAAACGCAAAGTCTCAGGTGACAGCAGCCA
CACTGAGACCACTGCGGAGGAGGTGCCAGAGGACCCTCTGCTGAAAGCCAAACGCCGACGAGTCTCTAAAGGGCTCCATCCTAAAAAACA
ACGCCACTTGCTGCACCTTAGAGAACGATGGGAGCAGCAGGTGTCGGCAGCAGATGGCAAACCTGGCCGGCAAAGCAGGAAGGAAGTGAC
CCAGGCCACTCAGCCTGAGGCCATTCCTCAGGGGACTAACATCACTGAAGAGAAACCTGGCAGGAAAAGGGCAGAGGCCAAAGGCAACAG
AAGCTGGTCGGAAGAGTCTCTTAAACCCAGTGACAATGAACAAGGCTTGCCTGTGTTCTCCGGCTCTCCGCCCATGAAGAGTCTTTCATC
CACCAGTGCAGGCGGCAAAAAGCAGGCTCAGCCAAGCTGCGCACCAGCCTCCAGGCCGCCTGCCAAACAGCAGAAAATTAAAGAAAACCA
GAAGACAGATGTGCTGTGTGCAGACGAAGAAGAGGATTGCCAGGCTGCCTCCCTGCTGCAGAAATACACCGACAACAGCGAGAAGCCATC
CGGGAAGAGACTGTGCAAAACCAAACACTTGATCCCTCAGGAGTCCAGGCGGGGATTGCCACTGACAGGGGAATACTACGTGGAGAATGC
CGATGGCAAGGTGACTGTCCGGAGATTCAGAAAGCGGCCGGAGCCCAGTTCGGACTATGATCTGTCACCAGCCAAGCAGGAGCCAAAGCC
CTTCGACCGCTTGCAGCAACTGCTACCAGCCTCCCAGTCCACACAGCTGCCATGCTCAAGTTCCCCTCAGGAGACCACCCAGTCTCGCCC
TATGCCGCCGGAAGCACGGAGACTTATTGTCAATAAGAACGCTGGCGAGACCCTTCTGCAGCGGGCAGCCAGGCTTGGCTATGAGGAAGT
GGTCCTGTACTGCTTAGAGAACAAGATTTGTGATGTAAATCATCGGGACAACGCAGGTTACTGCGCCCTGCATGAAGCTTGTGCTAGGGG
CTGGCTCAACATTGTGCGACACCTCCTTGAATATGGCGCTGATGTCAACTGTAGTGCCCAGGATGGAACCAGGCCTCTGCACGATGCTGT
TGAGAACGATCACTTGGAAATTGTCCGACTACTTCTCTCTTATGGTGCTGACCCCACCTTGGCTACGTACTCAGGTAGAACCATCATGAA
AATGACCCACAGTGAACTTATGGAAAAGTTCTTAACAGATTATTTAAATGACCTCCAGGGTCGCAATGATGATGACGCCAGTGGCACTTG
GGACTTCTATGGCAGCTCTGTTTGTGAACCAGATGATGAAAGTGGCTATGATGTTTTAGCCAACCCCCCAGGACCAGAAGACCAGGATGA
TGATGACGATGCCTATAGCGATGTGTTTGAATTTGAATTTTCAGAGACCCCCCTCTTACCGTGTTATAACATCCAAGTATCTGTGGCTCA
GGGGCCACGAAACTGGCTACTGCTTTCGGATGTCCTTAAGAAATTGAAAATGTCCTCCCGCATATTTCGCTGCAATTTTCCAAACGTGGA
AATTGTCACCATTGCAGAGGCAGAATTTTATCGGCAGGTTTCTGCAAGTCTCTTGTTCTCTTGCTCCAAAGACCTGGAAGCCTTCAACCC
TGAAAGTAAGGAGCTGTTAGATCTGGTGGAATTCACGAACGAAATTCAGACTCTGCTGGGCTCCTCTGTAGAGTGGCTCCACCCCAGTGA
TCTGGCCTCAGACAACTACTGGTGAGCAAGCTGGACCCACCATGTACAGTGTGTTATAGTGTTAATCCTTGTGCATATGTGTCATAATAC
AACTATTTCTGTAAAGAAAGGACACTATTACATATGAAAATATCTCTTCTTTATATAAGAGAAATTACTCCAGTCAGAAGGACTTAGAAA
CATGTTTTTTTCCTTTTAAACTTTTAAGTCAGTTTTTATGAAGTTGTTATAATGTTTCTTTACTTTTCAATGCACACATGCTTTGGGATA
CGTTTGTTTTTACTTGGAACATTTGTTTCTTTTCTTTTTTAAGGAGAAAAAAAAATGAGTAAAAGGAGCTCCACACTTTGACTTAATTTC
ATACAAAGCTCTGATGACAGGCCATGACTGTAGAGTGGTCAGAACTGTGTGGTTGGTTTGAGGGAGCGAATTCGGGGAAGGCACTTGGTG
ATATAACTTTGTTTTGTTTACAGAGTACCTGCTCGGGCCAGGTAAATGCTATTGGATGTAATCCAGTAGTGTGTAATATAAATTCAAACC
ATATCCACACACAACAACTAATTGTATGAAACTTTTATATCCTAATTTAAAAGCTGTGAAATTAGTTTTCACGCATCAAACCGGATTGTT
TATATGTTTAAACATTTTATGCTCTTATTTAAAGAAGACTTTGAGCTATTTTTTTCTGTACCCTGTAAAATATTGAAAACTAACATAATA
TGTTGAGGTTGCTTGGAAATGTACATAAAACTAAAATTTTCTGAATCGTGTGTTTATGTTTGAAATCTGTGTTTTAACTTTGTAAGTAAA

>In-frame_EP300_ENST00000263253_chr22_41572532_+_BCOR_ENST00000342274_chrX_39930412_-_9256nt
CTTGTTTGTGTGCTAGGCTGGGGGGGAGAGAGGGCGAGAGAGAGCGGGCGAGAGTGGGCAAGCAGGACGCCGGGCTGAGTGCTAACTGCG
GGAGCCAGAGAGTGCGGAGGGGAGTCGGGTCGGAGAGAGGCGGCAGGGGCCGAGACAGTGGCAGGGGGCCCGGGGCGCACGGGCTGAGGC
GACCCCCAGCCCCCTCCCGTCCGCACACACCCCCACCGCGGTCCAGCAGCCGGGCCGGCGTCGACGCCTAGGGGGGACCATTACATAACC
CCGCGCCCCGCGGCGTCTTCTCCCGCCGCCGCGGGCGGCCCCGAACGGAGCCCCGGGGGGCGGGCGCTCCCAGCACCTGGCCGCCGGCGG
TGGGGGCCGTAGCAGCGGCCGTATTTATTTATTTTCCGCGGGAAAGGAAGGCGAAGGAGGGGAGCGCGGCGCGAGGAGGGGCCGCCTGCG
CCGCCGCCGGAGCGGGGCCTCCTCGGTGGGCTCCGCGTCGGCGCGGGCGTGCGGGCGGCGCTGCTCGGCCCGGCCCCCTCGGCCCTCTGG
TCCGGCCAGCTCCGCTCCCGGCGTCCTTGCCGCGCCTCCGCCGGCCGCCGCGCGATGTGAGGCGGCGGCGCCAGCCTGGCTCTCGGCTCG
GGCGAGTTCTCTGCGGCCATTAGGGGCCGGTGCGGCGGCGGCGGCGCGGAGCGCGGCGGCAGGAGGAGGGTTCGGAGGGTGGGGGCGCAG
GCCCGGGAGGGGGCACCGGGAGGAGGTGAGTGTCTCTTGTCGCCTCCTCCTCTCCCCCCTTTTCGCCCCCGCCTCCTTGTGGCGATGAGA
AGGAGGAGGACAGCGCCGAGGAGGAAGAGGTTGATGGCGGCGGCGGAGCTCCGAGAGACCTCGGCTGGGCAGGGGCCGGCCGTGGCGGGC
CGGGGACTGCGCCTCTAGAGCCGCGAGTTCTCGGGAATTCGCCGCAGCGGACGCGCTCGGCGAATTTGTGCTCTTGTGCCCTCCTCCGGG
CTTGGGCCCAGGCCCGGCCCCTCGCACTTGCCCTTACCTTTTCTATCGAGTCCGCATCCCTCTCCAGCCACTGCGACCCGGCGAAGAGAA
AAAGGAACTTCCCCCACCCCCTCGGGTGCCGTCGGAGCCCCCCAGCCCACCCCTGGGTGCGGCGCGGGGACCCCGGGCCGAAGAAGAGAT
TTCCTGAGGATTCTGGTTTTCCTCGCTTGTATCTCCGAAAGAATTAAAAATGGCCGAGAATGTGGTGGAACCGGGGCCGCCTTCAGCCAA
GCGGCCTAAACTCTCATCTCCGGCCCTCTCGGCGTCCGCCAGCGATGGCACAGATTTTGGCTCTCTATTTGACTTGGAGCACGACTTACC
AGATGAATTAATCAACTCTACAGAATTGGGACTAACCAATGGTGGTGATATTAATCAGCTTCAGACAAGTCTTGGCATGGTACAAGATGC
AGCTTCTAAACATAAACAGCTGTCAGAATTGCTGCGATCTGGTAGTTCCCCTAACCTCAATATGGGAGTTGGTGGCCCAGGTCAAGTCAT
GGCCAGCCAGGCCCAACAGAGCAGTCCTGGATTAGGTTTGATAAATAGCATGGTCAAAAGCCCAATGACACAGGCAGGCTTGACTTCTCC
CAACATGGGGATGGGCACTAGTGGACCAAATCAGGGTCCTACGCAGTCAACAGGTATGATGAACAGTCCAGTAAATCAGCCTGCCATGGG
AATGAACACAGGGATGAATGCGGGCATGAATCCTGGAATGTTGGCTGCAGGCAATGGACAAGGGATAATGCCTAATCAAGTCATGAACGG
TTCAATTGGAGCAGGCCGAGGGCGACAGAATATGCAGTACCCAAACCCAGGCATGGGAAGTGCTGGCAACTTACTGACTGAGCCTCTTCA
GCAGGGCTCTCCCCAGATGGGAGGACAAACAGGATTGAGAGGCCCCCAGCCTCTTAAGATGGGAATGATGAACAACCCCAATCCTTATGG
TTCACCATATACTCAGAATCCTGGACAGCAGATTGGAGCCAGTGGCCTTGGTCTCCAGATTCAGACAAAAACTGTACTATCAAATAACTT
ATCTCCATTTGCTATGGACAAAAAGGCAGTTCCTGGTGGAGGAATGCCCAACATGGGTCAACAGCCAGCCCCGCAGGTCCAGCAGCCAGG
CCTGGTGACTCCAGTTGCCCAAGGGATGGGTTCTGGAGCACATACAGCTGATCCAGAGAAGCGCAAGCTCATCCAGCAGCAGCTTGTTCT
CCTTTTGCATGCTCACAAGTGCCAGCGCCGGGAACAGGCCAATGGGGAAGTGAGGCAGTGCAACCTTCCCCACTGTCGCACAATGAAGAA
TGTCCTAAACCACATGACACACTGCCAGTCAGGCAAGTCTTGCCAAGTGGCACACTGTGCATCTTCTCGACAAATCATTTCACACTGGAA
GAATTGTACAAGACATGATTGTCCTGTGTGTCTCCCCCTCAAAAATGCTGGTGATAAGAGAAATCAACAGCCAATTTTGACTGGAGCACC
CGTTGGACTTGGAAATCCTAGCTCTCTAGGGGTGGGTCAACAGTCTGCCCCCAACCTAAGCACTGTTAGTCAGATTGATCCCAGCTCCAT
AGAAAGAGCCTATGCAGCTCTTGGACTACCCTATCAAGTAAATCAGATGCCGACACAACCCCAGGTGCAAGCAAAGAACCAGCAGAATCA
GCAGCCTGGGCAGTCTCCCCAAGGCATGCGGCCCATGAGCAACATGAGTGCTAGTCCTATGGGAGTAAATGGAGGTGTAGGAGTTCAAAC
GCCGAGTCTTCTTTCTGACTCAATGTTGCATTCAGCCATAAATTCTCAAAACCCAATGATGAGTGAAAATGCCAGTGTGCCCTCCCTGGG
TCCTATGCCAACAGCAGCTCAACCATCCACTACTGGAATTCGGAAACAGTGGCACGAAGATATTACTCAGGATCTTCGAAATCATCTTGT
TCACAAACTCGTCCAAGCCATATTTCCTACGCCGGATCCTGCTGCTTTAAAAGACAGACGGATGGAAAACCTAGTTGCATATGCTCGGAA
AGTTGAAGGGGACATGTATGAATCTGCAAACAATCGAGCGGAATACTACCACCTTCTAGCTGAGAAAATCTATAAGATCCAGAAAGAACT
AGAAGAAAAACGAAGGACCAGACTACAGAAGCAGAACATGCTACCAAATGCTGCAGGCATGGTTCCAGTTTCCATGAATCCAGGGCCTAA
CATGGGACAGCCGCAACCAGGAATGACTTCTAATGGCCCTCTACCTGACCCAAGTATGATCCGTGGCAGTGTGCCAAACCAGATGATGCC
TCGAATAACTCCACAATCTGGTTTGAATCAATTTGGCCAGATGAGCATGGCCCAGCCCCCTATTGTACCCCGGCAAACCCCTCCTCTTCA
GCACCATGGACAGTTGGCTCAACCTGGAGCTCTCAACCCGCCTATGGGCTATGGGCCTCGTATGCAACAGCCTTCCAACCAGGGCCAGTT
CCTTCCTCAGACTCAGTTCCCATCACAGGGAATGAATGTAACAAATATCCCTTTGGCTCCGTCCAGCGGTCAAGCTCCAGTGTCTCAAGC
ACAAATGTCTAGTTCTTCCTGCCCGGTGAACTCTCCTATAATGCCTCCAGGGTCTCAGGGGAGCCACATTCACTGTCCCCAGCTTCCTCA
ACCAGCTCTTCATCAGAATTCACCCTCGCCTGTACCTAGTCGTACCCCCACCCCTCACCATACTCCCCCAAGCATAGGGGCTCAGCAGCC
ACCAGCAACAACAATTCCAGCCCCTGTTCCTACACCTCCTGCCATGCCACCTGGGCCACAGTCCCAGGCTCTACATCCCCCTCCAAGGCA
GACACCTACACCACCAACAACACAACTTCCCCAACAAGTGCAGCCTTCACTTCCTGCTGCACCTTCTGCTGACCAGCCCCAGCAGCAGCC
TCGCTCACAGCAGAGCACAGCAGCGTCTGTTCCTACCCCAACAGCACCGCTGCTTCCTCCGCAGCCTGCAACTCCACTTTCCCAGCCAGC
TGTAAGCATTGAAGGACAGGTATCAAATCCTCCATCTACTAGTAGCACAGAAGTGAATTCTCAGGCCATTGCTGAGAAGCAGCCTTCCCA
GGAAGTGAAGATGGAGGCCAAAATGGAAGTGGATCAACCAGAACCAGCAGATACTCAGCCGGAGGATATTTCAGAGTCTAAAGTGGAAGA
CTGTAAAATGGAATCTACCGAAACAGAAGAGAGAAGCACTGAGTTAAAAACTGAAATAAAAGAGGAGGAAGACCAGCCAAGTACTTCAGC
TACCCAGTCATCTCCGGCTCCAGGACAGTCAAAGAAAAAGATTTTCAAACCAGAAGAACTACGACAGGCACTGATGCCAACTTTGGAGGC
ACTTTACCGTCAGGATCCAGAATCCCTTCCCTTTCGTCAACCTGTGGACCCTCAGCTTTTAGGAATCCCTGATTACTTTGATATTGTGAA
GAGCCCCATGGATCTTTCTACCATTAAGAGGAAGTTAGACACTGGACAGTATCAGGAGCCCTGGCAGTATGTCGATGATATTTGGCTTAT
GTTCAATAATGCCTGGTTATATAACCGGAAAACATCACGGGTATACAAATACTGCTCCAAGCTCTCTGAGGTCTTTGAACAAGAAATTGA
CCCAGTGATGCAAAGCCTTGGATACTGTTGTGGCAGAAAGTTGGAGTTCTCTCCACAGACACTGTGTTGCTACGGCAAACAGTTGTGCAC
AATACCTCGTGATGCCACTTATTACAGTTACCAGAACAGGTATCATTTCTGTGAGAAGTGTTTCAATGAGATCCAAGGGGAGAGCGTTTC
TTTGGGGGATGACCCTTCCCAGCCTCAAACTACAATAAATAAAGAACAATTTTCCAAGAGAAAAAATGACACACTGGATCCTGAACTGTT
TGTTGAATGTACAGAGTGCGGAAGAAAGATGCATCAGATCTGTGTCCTTCACCATGAGATCATCTGGCCTGCTGGATTCGTCTGTGATGG
CTGTTTAAAGAAAAGTGCACGAACTAGGAAAGAAAATAAGTTTTCTGCTAAAAGGTTGCCATCTACCAGACTTGGCACCTTTCTAGAGAA
TCGTGTGAATGACTTTCTGAGGCGACAGAATCACCCTGAGTCAGGAGAGGTCACTGTTAGAGTAGTTCATGCTTCTGACAAAACCGTGGA
AGTAAAACCAGGCATGAAAGCAAGGTTTGTGGACAGTGGAGAGATGGCAGAATCCTTTCCATACCGAACCAAAGCCCTCTTTGCCTTTGA
AGAAATTGATGGTGTTGACCTGTGCTTCTTTGGCATGCATGTTCAAGAGTATGGCTCTGACTGCCCTCCACCCAACCAGAGGAGAGTATA
CATATCTTACCTCGATAGTGTTCATTTCTTCCGTCCTAAATGCTTGAGGACTGCAGTCTATCATGAAATCCTAATTGGATATTTAGAATA
TGTCAAGAAATTAGGTTACACAACAGGGCATATTTGGGCATGTCCACCAAGTGAGGGAGATGATTATATCTTCCATTGCCATCCTCCTGA
CCAGAAGATACCCAAGCCCAAGCGACTGCAGGAATGGTACAAAAAAATGCTTGACAAGGCTGTATCAGAGCGTATTGTCCATGACTACAA
GGATATTTTTAAACAAGCTACTGAAGATAGATTAACAAGTGCAAAGGAATTGCCTTATTTCGAGGGTGATTTCTGGCCCAATGTTCTGGA
AGAAAGCATTAAGGAACTGGAACAGGAGGAAGAAGAGAGAAAACGAGAGGAAAACACCAGCAATGAAAGCACAGATGTGACCAAGGGAGA
CAGCAAAAATGCTAAAAAGAAGAATAATAAGAAAACCAGCAAAAATAAGAGCAGCCTGAGTAGGGGCAACAAGAAGAAACCCGGGATGCC
CAATGTATCTAACGACCTCTCACAGAAACTATATGCCACCATGGAGAAGCATAAAGAGGTCTTCTTTGTGATCCGCCTCATTGCTGGCCC
TGCTGCCAACTCCCTGCCTCCCATTGTTGATCCTGATCCTCTCATCCCCTGCGATCTGATGGATGGTCGGGATGCGTTTCTCACGCTGGC
AAGGGACAAGCACCTGGAGTTCTCTTCACTCCGAAGAGCCCAGTGGTCCACCATGTGCATGCTGGTGGAGCTGCACACGCAGAGCCAGGA
CCGCTTTGTCTACACCTGCAATGAATGCAAGCACCATGTGGAGACACGCTGGCACTGTACTGTCTGTGAGCGTGCAATGATGCGCTTCTC
AGAGTTGGAGATGAAAGAAAGAGAAGGTGGCCACCCAGCAACCAAAGACTCCGAGATGTGCAAATTCAGCCCAGCCGACTGGGAAAGGTT
GAAAGGAAATCAGGACAAAAAGCCAAAGTCGGTCACCCTGGAGGAGGCCATTGCAGAACAGAACGAAAGTGAGAGATGCGAGTATAGTGT
TGGAAACAAGCACCGTGATCCCTTTGAAGCCCCAGAGGACAAAGATCTTCCTGTGGAGAAGTACTTTGTGGAGAGGCAGCCTGTGAGCGA
GCCTCCCGCAGACCAGGTGGCCTCGGACATGCCTCACAGCCCCACCCTCCGGGTGGACAGGAAACGCAAAGTCTCAGGTGACAGCAGCCA
CACTGAGACCACTGCGGAGGAGGTGCCAGAGGACCCTCTGCTGAAAGCCAAACGCCGACGAGTCTCTAAAGGGCTCCATCCTAAAAAACA
ACGCCACTTGCTGCACCTTAGAGAACGATGGGAGCAGCAGGTGTCGGCAGCAGATGGCAAACCTGGCCGGCAAAGCAGGAAGGAAGTGAC
CCAGGCCACTCAGCCTGAGGCCATTCCTCAGGGGACTAACATCACTGAAGAGAAACCTGGCAGGAAAAGGGCAGAGGCCAAAGGCAACAG
AAGCTGGTCGGAAGAGTCTCTTAAACCCAGTGACAATGAACAAGGCTTGCCTGTGTTCTCCGGCTCTCCGCCCATGAAGAGTCTTTCATC
CACCAGTGCAGGCGGCAAAAAGCAGGCTCAGCCAAGCTGCGCACCAGCCTCCAGGCCGCCTGCCAAACAGCAGAAAATTAAAGAAAACCA
GAAGACAGATGTGCTGTGTGCAGACGAAGAAGAGGATTGCCAGGCTGCCTCCCTGCTGCAGAAATACACCGACAACAGCGAGAAGCCATC
CGGGAAGAGACTGTGCAAAACCAAACACTTGATCCCTCAGGAGTCCAGGCGGGGATTGCCACTGACAGGGGAATACTACGTGGAGAATGC
CGATGGCAAGGTGACTGTCCGGAGATTCAGAAAGCGGCCGGAGCCCAGTTCGGACTATGATCTGTCACCAGCCAAGCAGGAGCCAAAGCC
CTTCGACCGCTTGCAGCAACTGCTACCAGCCTCCCAGTCCACACAGCTGCCATGCTCAAGTTCCCCTCAGGAGACCACCCAGTCTCGCCC
TATGCCGCCGGAAGCACGGAGACTTATTGTCAATAAGAACGCTGGCGAGACCCTTCTGCAGCGGGCAGCCAGGCTTGGCTATGAGGAAGT
GGTCCTGTACTGCTTAGAGAACAAGATTTGTGATGTAAATCATCGGGACAACGCAGGTTACTGCGCCCTGCATGAAGCTTGTGCTAGGGG
CTGGCTCAACATTGTGCGACACCTCCTTGAATATGGCGCTGATGTCAACTGTAGTGCCCAGGATGGAACCAGGCCTCTGCACGATGCTGT
TGAGAACGATCACTTGGAAATTGTCCGACTACTTCTCTCTTATGGTGCTGACCCCACCTTGGCTACGTACTCAGGTAGAACCATCATGAA
AATGACCCACAGTGAACTTATGGAAAAGTTCTTAACAGATTATTTAAATGACCTCCAGGGTCGCAATGATGATGACGCCAGTGGCACTTG
GGACTTCTATGGCAGCTCTGTTTGTGAACCAGATGATGAAAGTGGCTATGATGTTTTAGCCAACCCCCCAGGACCAGAAGACCAGGATGA
TGATGACGATGCCTATAGCGATGTGTTTGAATTTGAATTTTCAGAGACCCCCCTCTTACCGTGTTATAACATCCAAGTATCTGTGGCTCA
GGGGCCACGAAACTGGCTACTGCTTTCGGATGTCCTTAAGAAATTGAAAATGTCCTCCCGCATATTTCGCTGCAATTTTCCAAACGTGGA
AATTGTCACCATTGCAGAGGCAGAATTTTATCGGCAGGTTTCTGCAAGTCTCTTGTTCTCTTGCTCCAAAGACCTGGAAGCCTTCAACCC
TGAAAGTAAGGAGCTGTTAGATCTGGTGGAATTCACGAACGAAATTCAGACTCTGCTGGGCTCCTCTGTAGAGTGGCTCCACCCCAGTGA
TCTGGCCTCAGACAACTACTGGTGAGCAAGCTGGACCCACCATGTACAGTGTGTTATAGTGTTAATCCTTGTGCATATGTGTCATAATAC
AACTATTTCTGTAAAGAAAGGACACTATTACATATGAAAATATCTCTTCTTTATATAAGAGAAATTACTCCAGTCAGAAGGACTTAGAAA
CATGTTTTTTTCCTTTTAAACTTTTAAGTCAGTTTTTATGAAGTTGTTATAATGTTTCTTTACTTTTCAATGCACACATGCTTTGGGATA
CGTTTGTTTTTACTTGGAACATTTGTTTCTTTTCTTTTTTAAGGAGAAAAAAAAATGAGTAAAAGGAGCTCCACACTTTGACTTAATTTC
ATACAAAGCTCTGATGACAGGCCATGACTGTAGAGTGGTCAGAACTGTGTGGTTGGTTTGAGGGAGCGAATTCGGGGAAGGCACTTGGTG
ATATAACTTTGTTTTGTTTACAGAGTACCTGCTCGGGCCAGGTAAATGCTATTGGATGTAATCCAGTAGTGTGTAATATAAATTCAAACC
ATATCCACACACAACAACTAATTGTATGAAACTTTTATATCCTAATTTAAAAGCTGTGAAATTAGTTTTCACGCATCAAACCGGATTGTT
TATATGTTTAAACATTTTATGCTCTTATTTAAAGAAGACTTTGAGCTATTTTTTTCTGTACCCTGTAAAATATTGAAAACTAACATAATA
TGTTGAGGTTGCTTGGAAATGTACATAAAACTAAAATTTTCTGAATCGTGTGTTTATGTTTGAAATCTGTGTTTTAACTTTGTAAGTAAA


Top

FusionGenePPI for EP300_BCOR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
EP300TFAP2A, EGR1, MAF, PROX1, CITED2, JMY, BRCA1, NCOA3, TP53, SS18L1, PIAS3, CLOCK, ARNTL, NPAS2, KLF5, ING4, ING5, N4BP2, MEF2D, PPARG, ESR1, KAT2B, RELA, YY1, SMAD2, ETS1, ETS2, ELK1, SS18, CDX2, PAX6, CREB1, USF2, FEN1, EP300, MEF2A, THRA, RORA, MYOD1, TSG101, MYBL2, ING1, SMAD1, TWIST1, NEUROD1, HAND2, DTX1, ASCL1, GPS2, HNRNPU, SMAD7, MAML1, EID1, RBM14, CITED4, HIF1A, MDM4, NCOA6, TADA3, GATA6, BCL3, TCF3, MGMT, DDX5, CITED1, PELP1, SREBF2, NFATC2, TRIP4, STAT2, STAT1, TDG, NUP98, TRERF1, TGS1, NEUROG1, SNIP1, SMAD4, IRF2, STAT3, NR4A1, HNF1A, LEF1, MEF2C, MDM2, CCND1, PPARA, PCNA, XPA, TAL1, PTMA, CEBPB, POLR2A, COPS6, SUB1, STAT6, ZBTB17, HIST3H3, HIST4H4, TAF1B, NAP1L1, NAP1L4, CREBBP, USF1, HDAC6, RECQL4, BTRC, ANAPC7, ANAPC5, CDC16, ANAPC2, CDH1, CDC20, HDAC3, CDT1, ATF4, REL, DDX17, MAX, SP1, MAP3K5, PAK2, GRB2, CHUK, NOTCH1, ELSPBP1, SOX9, HIST1H3A, CTBP2, KAT6A, TBX21, SIRT2, NCOR1, NCOR2, PARP1, PPARGC1A, CTTN, PPARD, CARM1, RUNX1, HIPK2, ESR2, SMAD3, PLAGL1, HDAC1, ING2, SP3, RUNX2, CALCOCO1, GTF3C1, GTF3C3, GTF3C2, GTF3C5, MTA1, SMAD5, VHL, RUNX3, HSP90AA2P, NFKB1, IRF1, HIST2H2AC, HIST1H4A, MYC, JUND, ETV1, KLF13, PGR, PTMS, JUN, BCL6, AR, ATXN3, CTBP1, MTF1, NPM1, GRIP1, RARA, HIST1H2AB, HIST1H2BB, SREBF1, DEK, ATXN7, YAP1, TP73, HIST1H1D, HIST2H2AB, VDR, MYB, SRCAP, PRMT1, CDKN1A, GATA4, NFYB, TCF12, JUNB, SRY, PRDM2, CTF1, KPNA2, HIST2H2BE, AKT1, XRCC6, GATA2, SNW1, NCOA1, KLF4, NR3C1, FOSL1, CTNNB1, NFATC1, MAPK1, PAX5, GABPA, KDM1A, ATR, NUTM1, BRD4, KLF8, TGFBR1, IRF5, ZBTB7B, MAPT, RPS6KB1, RPS6KB2, NR1H4, FOXO3, SOX4, HOXD10, HOXD4, SMARCA2, MDC1, DDX24, ACTA1, ANXA2, HERC1, TP53BP1, MSH6, RAD50, NBN, MRE11A, NEDD1, ACTA2, CRTC2, IRF3, ATF2, POU3F2, TBP, GTF2B, CDK2, CRX, HMGN1, HMGN2, AHR, ARNT, RPS6KA5, NUPR1, PAXIP1, CXCL8, MAGEA11, NCOA2, IRF7, PCK1, BAG6, SPHK1, NFYA, KLF16, KAT5, MAPK14, HBP1, TACC2, FOS, FOSB, FOSL2, RXRA, TCF4, PIN1, MAP9, STAT5A, KLF11, ZNF148, DDB2, DDB1, CD44, GAPDH, ERCC8, FBXO3, TNK2, ZBTB16, SKP2, HIST2H3C, HIST2H4A, ZNF76, EPAS1, HIST1H1A, PIK3R1, NABP2, PKM, APEX1, ASCL2, YBX1, CBX8, STRAP, TCL1A, ATG7, KLF1, MYBBP1A, RPS26, TNIP2, GOLGA2, CFH, DECR2, PLG, MAGED1, TINAGL1, KRT18, IMMT, MSTO1, WDR59, EWSR1, EPO, GAA, ITIH3, PCK2, PLSCR1, POLD2, RPL27, SEPP1, THPO, TRAF2, MCM3AP, NOXA1, HNRNPUL1, FBXL5, SERTAD1, UBQLN1, KCTD5, PLSCR2, VPS18, SAV1, HPS6, ZC3H12A, ARSF, C1R, CLTC, DAO, CNOT4, BCAS2, ATF5, ACSM5, ACTB, DYRK1B, DYRK1A, PTGS2, DDIT3, COPS2, ZBTB48, SIRT1, ZBTB8A, E2F1, AURKB, COMMD1, PRDM6, ELF3, FOXO1, KLF2, HSPA5, FBXW8, FBXW2, UBE2D1, SENP3, BANP, ASCC1, TERF2, TERF1, CEBPD, PRKCB, PRKCA, PRKCD, PAX8, ZEB1, FOXP3, FHL1, RB1, NANOG, BRMS1, PPP1R13B, TP53BP2, PPP1R13L, CCNB1, TP63, SATB1, UBC, MITF, EID2, CDK1, SPIB, MAPK8, CRTC1, MAML2, POLB, PPP2R5C, PPP2CA, DNA2, PDHX, FHL2, ASH2L, CXXC1, SETD1A, WDR82, WDR5, RBBP5, PRKAA1, NEIL2, MN1, DYNC1I1, BMI1, SUMO2, FLII, ILF2, CCNA2, C3orf62, BRD7, ZBTB33, RERE, KLF15, ZBTB49, ORC2, MCM2, PRKDC, MCM4, MCM3, ILF3, MCM5, EEF2, EEF1A1, MORF4L1, RUVBL2, AUTS2, TCF7L2, UBE2I, MED23, COBL, SDC1, PSMD10, SNAI1, ZNF350, SMC1A, HEMGN, GATA1, NR3C2, GCKR, CIITA, YWHAZ, ITGAV, MKL1, ZEB2, GLUL, CHD4, HSF1, RORC, SRC, HNRNPA2B1, CTGF, SPATA1, HSPA8, JUP, LAMP2, TRIM25, XRCC5, MTDH, PIAS1, ARHGDIA, RPTOR, MTORBCORMLLT3, BCL6, HDAC1, HDAC3, HDAC4, HDAC6, PCGF1, KDM2B, HSPA4, RING1, RNF2, RYBP, SKP1, ZBTB7A, SP1, MLLT1, BCOR, YAF2, NACC1, USP7, PCGF3, UBTD1, NCOR2, NAA10, PCGF5, EED, CBX7, QPRT, CARD8, DCAF15, CLEC11A, CTBP1, FBXW11, B9D2, HSPD1, TRIM27, TCF3, KCNAB2, NFS1, PTPN1, HMG20A, IPO8, DNAJC11, RNASEH2B, ACTL8, CCDC124, ESR1, ACACB, AK2, ANGEL2, ATG101, C10orf131, CCDC101, CDK2AP1, CS, DDB1, DYNC1LI1, EIF3D, ERCC8, IBTK, IDH3G, ING4, KDELR2, LETMD1, NAA50, NAP1L4, NCAPD2, NSF, OTX2, PCGF2, PCMT1, PQBP1, PRCP, SALL1, SATB2, SCAF11, SENP2, SMC4, TCEB1, TCP1, TIA1, TKT, TMTC1, TRPM1, USP42, EYA2, HAO2, ERP44, SIRT6, L3MBTL1, NCAPH2, CDC16, CELA1, IL17RA, CSN1S1, C6orf141, PRR20E, NR3C1, AR, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30312_13916872415ALX1
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30311397_139916872415histone
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30312_14916872415RORA


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30312003_221216872415HTLV-1 Tax
HgeneEP300chr22:41572532chrX:39930412ENST00000263253+30312041_224016872415NCOA2
TgeneBCORchr22:41572532chrX:39930412ENST00000342274-415498_51410171722BCL6
TgeneBCORchr22:41572532chrX:39930412ENST00000378444-415498_51410171756BCL6
TgeneBCORchr22:41572532chrX:39930412ENST00000378455-314498_5149991704BCL6
TgeneBCORchr22:41572532chrX:39930412ENST00000397354-415498_51410171722BCL6


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for EP300_BCOR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for EP300_BCOR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneEP300C0279626Squamous cell carcinoma of esophagus2CTD_human
HgeneEP300C0001973Alcoholic Intoxication, Chronic1PSYGENET
HgeneEP300C0005695Bladder Neoplasm1CTD_human
HgeneEP300C0007137Squamous cell carcinoma1CTD_human
HgeneEP300C0007138Carcinoma, Transitional Cell1CTD_human
HgeneEP300C0010606Adenoid Cystic Carcinoma1CTD_human
HgeneEP300C0014170Endometrial Neoplasms1CTD_human
HgeneEP300C0025202melanoma1CTD_human
HgeneEP300C0028754Obesity1CTD_human
HgeneEP300C0038325Stevens-Johnson Syndrome1CTD_human
HgeneEP300C0079772T-Cell Lymphoma1CTD_human
HgeneEP300C0149925Small cell carcinoma of lung1CTD_human
HgeneEP300C0152013Adenocarcinoma of lung (disorder)1CTD_human
HgeneEP300C0376634Craniofacial Abnormalities1CTD_human
HgeneEP300C1458155Mammary Neoplasms1CTD_human
TgeneBCORC1846265Microphthalmia, syndromic 22CTD_human;ORPHANET;UNIPROT
TgeneBCORC0010606Adenoid Cystic Carcinoma1CTD_human
TgeneBCORC0022665Kidney Neoplasm1CTD_human
TgeneBCORC0029463Osteosarcoma1CTD_human
TgeneBCORC0206651Sarcoma, Clear Cell1CTD_human