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Fusion gene ID: 11587 |
FusionGeneSummary for ENAH_LIN9 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ENAH_LIN9 | Fusion gene ID: 11587 | Hgene | Tgene | Gene symbol | ENAH | LIN9 | Gene ID | 55740 | 286826 |
| Gene name | ENAH, actin regulator | lin-9 DREAM MuvB core complex component | |
| Synonyms | ENA|MENA|NDPP1 | BARA|BARPsv|Lin-9|TGS|TGS1|TGS2 | |
| Cytomap | 1q42.12 | 1q42.12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein enabled homologenabled homologmammalian enabled variant 11amammalian enabled variant pan | protein lin-9 homologTUDOR gene similar proteinbeta subunit-associated regulator of apoptosislin-9 homologpRB-associated proteinrb related pathway actortype I interferon receptor beta chain-associated protein | |
| Modification date | 20180520 | 20180523 | |
| UniProtAcc | Q8N8S7 | Q5TKA1 | |
| Ensembl transtripts involved in fusion gene | ENST00000366844, ENST00000366843, ENST00000284563, ENST00000391874, | ENST00000328205, ENST00000366801, ENST00000481685, | |
| Fusion gene scores | * DoF score | 7 X 7 X 5=245 | 3 X 1 X 3=9 |
| # samples | 10 | 3 | |
| ** MAII score | log2(10/245*10)=-1.29278174922785 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: ENAH [Title/Abstract] AND LIN9 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-FR-A7U8-06A | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000366844 | ENST00000328205 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| In-frame | ENST00000366844 | ENST00000366801 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| In-frame | ENST00000366844 | ENST00000481685 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| In-frame | ENST00000366843 | ENST00000328205 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| In-frame | ENST00000366843 | ENST00000366801 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| In-frame | ENST00000366843 | ENST00000481685 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| In-frame | ENST00000284563 | ENST00000328205 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| In-frame | ENST00000284563 | ENST00000366801 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| In-frame | ENST00000284563 | ENST00000481685 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| intron-3CDS | ENST00000391874 | ENST00000328205 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| intron-3CDS | ENST00000391874 | ENST00000366801 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
| intron-3CDS | ENST00000391874 | ENST00000481685 | ENAH | chr1 | 225840388 | - | LIN9 | chr1 | 226438620 | - |
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FusionProtFeatures for ENAH_LIN9 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ENAH | LIN9 |
| Ena/VASP proteins are actin-associated proteins involvedin a range of processes dependent on cytoskeleton remodeling andcell polarity such as axon guidance and lamellipodial andfilopodial dynamics in migrating cells. ENAH induces the formationof F-actin rich outgrowths in fibroblasts. Acts synergisticallywith BAIAP2-alpha and downstream of NTN1 to promote filipodiaformation (By similarity). {ECO:0000250,ECO:0000269|PubMed:11696321, ECO:0000269|PubMed:18158903}. | Acts as a tumor suppressor. Inhibits DNA synthesis. Itsability to inhibit oncogenic transformation is mediated throughits association with RB1. Plays a role in the expression of genesrequired for the G1/S transition. {ECO:0000269|PubMed:15538385,ECO:0000269|PubMed:16730350}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >LIN9 | chr1:225840388 | chr1:226438620 | ENST00000366801 | - | 8 | 14 | 354_413 | 311 | 508 | Coiled coil | Ontology_term=ECO:0000255 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 135_265 | 1 | 571 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 557_587 | 1 | 571 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 135_265 | 1 | 592 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 557_587 | 1 | 592 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 310_373 | 1 | 571 | Compositional bias | Note=Pro-rich |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 310_373 | 1 | 592 | Compositional bias | Note=Pro-rich |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 1_111 | 1 | 571 | Domain | WH1 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 1_111 | 1 | 592 | Domain | WH1 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 400_403 | 1 | 571 | Motif | Note=KLKR |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 400_403 | 1 | 592 | Motif | Note=KLKR |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 156_200 | 1 | 571 | Region | Note=9 X 5 AA tandem repeats of [LMQ]-E-[QR]-E-[QR] |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 391_411 | 1 | 571 | Region | Note=EVH2 block A |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 391_588 | 1 | 571 | Region | Note=EVH2 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 442_459 | 1 | 571 | Region | Note=EVH2 block B |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 554_588 | 1 | 571 | Region | Note=EVH2 block C |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 156_200 | 1 | 592 | Region | Note=9 X 5 AA tandem repeats of [LMQ]-E-[QR]-E-[QR] |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 391_411 | 1 | 592 | Region | Note=EVH2 block A |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 391_588 | 1 | 592 | Region | Note=EVH2 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 442_459 | 1 | 592 | Region | Note=EVH2 block B |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 554_588 | 1 | 592 | Region | Note=EVH2 block C |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 156_160 | 1 | 571 | Repeat | Note=1 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 161_165 | 1 | 571 | Repeat | Note=2 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 166_170 | 1 | 571 | Repeat | Note=3 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 171_175 | 1 | 571 | Repeat | Note=4 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 176_180 | 1 | 571 | Repeat | Note=5 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 181_185 | 1 | 571 | Repeat | Note=6 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 186_190 | 1 | 571 | Repeat | Note=7 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 191_195 | 1 | 571 | Repeat | Note=8 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366843 | - | 1 | 14 | 196_200 | 1 | 571 | Repeat | Note=9 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 156_160 | 1 | 592 | Repeat | Note=1 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 161_165 | 1 | 592 | Repeat | Note=2 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 166_170 | 1 | 592 | Repeat | Note=3 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 171_175 | 1 | 592 | Repeat | Note=4 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 176_180 | 1 | 592 | Repeat | Note=5 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 181_185 | 1 | 592 | Repeat | Note=6 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 186_190 | 1 | 592 | Repeat | Note=7 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 191_195 | 1 | 592 | Repeat | Note=8 |
| Hgene | >ENAH | chr1:225840388 | chr1:226438620 | ENST00000366844 | - | 1 | 15 | 196_200 | 1 | 592 | Repeat | Note=9 |
| Tgene | LIN9 | chr1:225840388 | chr1:226438620 | ENST00000328205 | - | 9 | 15 | 354_413 | 362 | 559 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for ENAH_LIN9 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ENAH_ENST00000366844_chr1_225840388_-_LIN9_ENST00000328205_chr1_226438620_-_198aa MRPDYQKFSXLKRNISRNXGKXTQKQKNXNHIPCPSALNFSGDMQQLFWSLNSXTRTXTKFCIKFNSIAMSLLQTRGSSLQISQQIXDAG VRKKHRKLFGMQIPQQDSPALKMKIXQTXFPGLQLFCYKLSVXQKEETXIPLNSNHLQTHXMISRVQXTLLISVAFRIMXKSMLHIFRVA >In-frame_ENAH_ENST00000366844_chr1_225840388_-_LIN9_ENST00000366801_chr1_226438620_-_198aa MRPDYQKFSXLKRNISRNXGKXTQKQKNXNHIPCPSALNFSGDMQQLFWSLNSXTRTXTKFCIKFNSIAMSLLQTRGSSLQISQQIXDAG VRKKHRKLFGMQIPQQDSPALKMKIXQTXFPGLQLFCYKLSVXQKEETXIPLNSNHLQTHXMISRVQXTLLISVAFRIMXKSMLHIFRVA >In-frame_ENAH_ENST00000366844_chr1_225840388_-_LIN9_ENST00000481685_chr1_226438620_-_164aa MRPDYQKFSXLKRNISRNXGKXTQKQKNXNHIPCPSALNFSGDMQQLFWSLNSXTRTXTKFCIKFNSIAMSLLQTRGSSLQISQQIXDAG >In-frame_ENAH_ENST00000366843_chr1_225840388_-_LIN9_ENST00000328205_chr1_226438620_-_198aa MRPDYQKFSXLKRNISRNXGKXTQKQKNXNHIPCPSALNFSGDMQQLFWSLNSXTRTXTKFCIKFNSIAMSLLQTRGSSLQISQQIXDAG VRKKHRKLFGMQIPQQDSPALKMKIXQTXFPGLQLFCYKLSVXQKEETXIPLNSNHLQTHXMISRVQXTLLISVAFRIMXKSMLHIFRVA >In-frame_ENAH_ENST00000366843_chr1_225840388_-_LIN9_ENST00000366801_chr1_226438620_-_198aa MRPDYQKFSXLKRNISRNXGKXTQKQKNXNHIPCPSALNFSGDMQQLFWSLNSXTRTXTKFCIKFNSIAMSLLQTRGSSLQISQQIXDAG VRKKHRKLFGMQIPQQDSPALKMKIXQTXFPGLQLFCYKLSVXQKEETXIPLNSNHLQTHXMISRVQXTLLISVAFRIMXKSMLHIFRVA >In-frame_ENAH_ENST00000366843_chr1_225840388_-_LIN9_ENST00000481685_chr1_226438620_-_164aa MRPDYQKFSXLKRNISRNXGKXTQKQKNXNHIPCPSALNFSGDMQQLFWSLNSXTRTXTKFCIKFNSIAMSLLQTRGSSLQISQQIXDAG >In-frame_ENAH_ENST00000284563_chr1_225840388_-_LIN9_ENST00000328205_chr1_226438620_-_198aa MRPDYQKFSXLKRNISRNXGKXTQKQKNXNHIPCPSALNFSGDMQQLFWSLNSXTRTXTKFCIKFNSIAMSLLQTRGSSLQISQQIXDAG VRKKHRKLFGMQIPQQDSPALKMKIXQTXFPGLQLFCYKLSVXQKEETXIPLNSNHLQTHXMISRVQXTLLISVAFRIMXKSMLHIFRVA >In-frame_ENAH_ENST00000284563_chr1_225840388_-_LIN9_ENST00000366801_chr1_226438620_-_198aa MRPDYQKFSXLKRNISRNXGKXTQKQKNXNHIPCPSALNFSGDMQQLFWSLNSXTRTXTKFCIKFNSIAMSLLQTRGSSLQISQQIXDAG VRKKHRKLFGMQIPQQDSPALKMKIXQTXFPGLQLFCYKLSVXQKEETXIPLNSNHLQTHXMISRVQXTLLISVAFRIMXKSMLHIFRVA >In-frame_ENAH_ENST00000284563_chr1_225840388_-_LIN9_ENST00000481685_chr1_226438620_-_164aa MRPDYQKFSXLKRNISRNXGKXTQKQKNXNHIPCPSALNFSGDMQQLFWSLNSXTRTXTKFCIKFNSIAMSLLQTRGSSLQISQQIXDAG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ENAH_ENST00000366844_chr1_225840388_-_LIN9_ENST00000328205_chr1_226438620_-_596nt ATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAAT CATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAG TTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGT GTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTT CCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCAT TAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAATCCATGTTGCACATATTCAGAGTGGCC >In-frame_ENAH_ENST00000366844_chr1_225840388_-_LIN9_ENST00000366801_chr1_226438620_-_596nt ATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAAT CATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAG TTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGT GTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTT CCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCAT TAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAATCCATGTTGCACATATTCAGAGTGGCC >In-frame_ENAH_ENST00000366844_chr1_225840388_-_LIN9_ENST00000481685_chr1_226438620_-_494nt ATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAAT CATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAG TTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGT GTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTT CCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCAT >In-frame_ENAH_ENST00000366843_chr1_225840388_-_LIN9_ENST00000328205_chr1_226438620_-_596nt ATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAAT CATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAG TTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGT GTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTT CCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCAT TAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAATCCATGTTGCACATATTCAGAGTGGCC >In-frame_ENAH_ENST00000366843_chr1_225840388_-_LIN9_ENST00000366801_chr1_226438620_-_596nt ATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAAT CATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAG TTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGT GTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTT CCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCAT TAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAATCCATGTTGCACATATTCAGAGTGGCC >In-frame_ENAH_ENST00000366843_chr1_225840388_-_LIN9_ENST00000481685_chr1_226438620_-_494nt ATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAAT CATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAG TTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGT GTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTT CCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCAT >In-frame_ENAH_ENST00000284563_chr1_225840388_-_LIN9_ENST00000328205_chr1_226438620_-_596nt ATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAAT CATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAG TTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGT GTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTT CCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCAT TAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAATCCATGTTGCACATATTCAGAGTGGCC >In-frame_ENAH_ENST00000284563_chr1_225840388_-_LIN9_ENST00000366801_chr1_226438620_-_596nt ATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAAT CATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAG TTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGT GTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTT CCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCAT TAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAATCCATGTTGCACATATTCAGAGTGGCC >In-frame_ENAH_ENST00000284563_chr1_225840388_-_LIN9_ENST00000481685_chr1_226438620_-_494nt ATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAAT CATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAG TTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGT GTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTT CCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ENAH_ENST00000366844_chr1_225840388_-_LIN9_ENST00000328205_chr1_226438620_-_2392nt GGTTCCTCGCGGCGATCCCGACTCTCCTCCCGCGGCTGCAGCAGCTGCCGGTTGCACACGGCCTCGGCGGCGGCGCGGCGAGCGCGGGCC TGTGGAGCGGCGGCCGGGCGCGCGGCCCCGGCGGGCACCCCTCAGAGGGCGGCCGAGGAAGCTCCGGGAGGAGGAGCAGGACCACGAGGA GGTGGGAGGCGGCGGCCGCCTGGGGACCAGCTCCGCGCCTCGGCCTCTCCGCCCCCTCCCCAGCCTTTCTCTCGCCCTCTTCTCCCACAC TCCCGGCCGGCGCCTCGGCTTTGTGCGAGGAGATGGTGTAGCCCCCTGGCCGCCGAAGGAGGAGCCGGACACTTGTCTCCCGTCTCCGAG CTGCTCCCCACCCCTGGAGGAGAGACCCCCCCCTCGGCTCGGCGCCTTCTGCGTCTCCCGGCTGGTGGGGAAGCCTCTGCGCCGCCGGCA CCATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAA ATCATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAA AGTTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAG GTGTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAAT TTCCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTC ATTAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAATCCATGTTGCACATATTCAGAGTGG CCTGAGCCAGATGGGAAACTTACATGCCTTTGCAGCAAATAACACCAACAGAGACTGAGTAAAGATTTCATTATTCCAACTGCACGGGAC ATTGTTTTTGAGAAGTTCTTTTCCTTTATATAGGCTTCCAACACCAAATAACCTAACTGCTGGAAAACAAGGGAAATTTAAATCTCCAAA TAAGGCATTTTAATAGACTGTACTGCTTCTTAAACCAGCATTGCTGACCAGCATTATATTTATTTTTCTTTTATTATTCAGATGCAGTAG CATTGCTTATGTTACATATGTTTATATTCACAAATATTTTTAAACTGAAATATCTGAACATAATATAATTTCGTGGAAGAATACATTGAC CATTTTTTTTAATGTGCATGAATTCACCGCAACACATGCAGACAACTGCTGCAATGGAGAGTATGAAGAAACCTGGTCTTTTTATTCATG TCGGTGGCAGTGTGGAAATTCCATCCAGAAAATTACAACTCCACTTGATTTAGTTGATCACCATCTCAGTCTTCAAAAGATAACATCATG AGGTGTGGGAAGTCCTAGTTTTAAGGAAACCACTGAAATATAGATGGGAAATGTGGACTTTACAAGTATATGTTATATATACTTGCAATG TGACATGGTTCTGTAGATCATTTTATAATAATAAATATTTTAATTTATCATAACATATAAAAGAAACCTTTGTTGTTTGTTGAAAGAAAA TGAAGGAACAGGGGGAAAAAAGGTGCAAAATGCTAAATTTCTAAAAATGGATTTGGCATGTCTTCCCATCAGTTCAGGTCAAAAGTGCAT TGTTGTGAGATTTATTAAAAAAAAAATGATAACACACTATTTTCATATTTTTTTGTTTATTTGCACAACTTTTAAACCAGATTACTGGTT AAAATCCAACAGTACACAATTTATAAAGTAAAAAGATTTTATAAGGAAAACAAATATAATAACCAGTGCTGTGAAATGCAGAAGAAAGGC TTGTTTTGGTTGTTTTTCTTTTTTAGGAAAACGCTGCCTAAAATGTTAATCTTGTAAAAAGTATGTATTTGGAATTTTCTTCGTTTTAAT AGAATATTATAAACTCAAAATATAAATTTTTTTCAAATTTGGAGTTTAAGATATAGCTGTAGAGGTGGTTTTAATTCCTTTAGATGTCTC ATAAAATGAGACTTTTTATATGTTAATGTATAATAAAACTGAAACAAGATTATTTTCCATTTGAAATTTTTGTATAGTTTAAAAAGGCTT CCGTATTCTTTGTTGGTATTGTGCCACTGCAGAACTTTAGTGCAGAGTTTATATTTAGCTAAACTGTTATGTTAATTAAGAAATGCATAA >In-frame_ENAH_ENST00000366844_chr1_225840388_-_LIN9_ENST00000366801_chr1_226438620_-_2385nt GGTTCCTCGCGGCGATCCCGACTCTCCTCCCGCGGCTGCAGCAGCTGCCGGTTGCACACGGCCTCGGCGGCGGCGCGGCGAGCGCGGGCC TGTGGAGCGGCGGCCGGGCGCGCGGCCCCGGCGGGCACCCCTCAGAGGGCGGCCGAGGAAGCTCCGGGAGGAGGAGCAGGACCACGAGGA GGTGGGAGGCGGCGGCCGCCTGGGGACCAGCTCCGCGCCTCGGCCTCTCCGCCCCCTCCCCAGCCTTTCTCTCGCCCTCTTCTCCCACAC TCCCGGCCGGCGCCTCGGCTTTGTGCGAGGAGATGGTGTAGCCCCCTGGCCGCCGAAGGAGGAGCCGGACACTTGTCTCCCGTCTCCGAG CTGCTCCCCACCCCTGGAGGAGAGACCCCCCCCTCGGCTCGGCGCCTTCTGCGTCTCCCGGCTGGTGGGGAAGCCTCTGCGCCGCCGGCA CCATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAA ATCATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAA AGTTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAG GTGTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAAT TTCCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTC ATTAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAATCCATGTTGCACATATTCAGAGTGG CCTGAGCCAGATGGGAAACTTACATGCCTTTGCAGCAAATAACACCAACAGAGACTGAGTAAAGATTTCATTATTCCAACTGCACGGGAC ATTGTTTTTGAGAAGTTCTTTTCCTTTATATAGGCTTCCAACACCAAATAACCTAACTGCTGGAAAACAAGGGAAATTTAAATCTCCAAA TAAGGCATTTTAATAGACTGTACTGCTTCTTAAACCAGCATTGCTGACCAGCATTATATTTATTTTTCTTTTATTATTCAGATGCAGTAG CATTGCTTATGTTACATATGTTTATATTCACAAATATTTTTAAACTGAAATATCTGAACATAATATAATTTCGTGGAAGAATACATTGAC CATTTTTTTTAATGTGCATGAATTCACCGCAACACATGCAGACAACTGCTGCAATGGAGAGTATGAAGAAACCTGGTCTTTTTATTCATG TCGGTGGCAGTGTGGAAATTCCATCCAGAAAATTACAACTCCACTTGATTTAGTTGATCACCATCTCAGTCTTCAAAAGATAACATCATG AGGTGTGGGAAGTCCTAGTTTTAAGGAAACCACTGAAATATAGATGGGAAATGTGGACTTTACAAGTATATGTTATATATACTTGCAATG TGACATGGTTCTGTAGATCATTTTATAATAATAAATATTTTAATTTATCATAACATATAAAAGAAACCTTTGTTGTTTGTTGAAAGAAAA TGAAGGAACAGGGGGAAAAAAGGTGCAAAATGCTAAATTTCTAAAAATGGATTTGGCATGTCTTCCCATCAGTTCAGGTCAAAAGTGCAT TGTTGTGAGATTTATTAAAAAAAAAATGATAACACACTATTTTCATATTTTTTTGTTTATTTGCACAACTTTTAAACCAGATTACTGGTT AAAATCCAACAGTACACAATTTATAAAGTAAAAAGATTTTATAAGGAAAACAAATATAATAACCAGTGCTGTGAAATGCAGAAGAAAGGC TTGTTTTGGTTGTTTTTCTTTTTTAGGAAAACGCTGCCTAAAATGTTAATCTTGTAAAAAGTATGTATTTGGAATTTTCTTCGTTTTAAT AGAATATTATAAACTCAAAATATAAATTTTTTTCAAATTTGGAGTTTAAGATATAGCTGTAGAGGTGGTTTTAATTCCTTTAGATGTCTC ATAAAATGAGACTTTTTATATGTTAATGTATAATAAAACTGAAACAAGATTATTTTCCATTTGAAATTTTTGTATAGTTTAAAAAGGCTT CCGTATTCTTTGTTGGTATTGTGCCACTGCAGAACTTTAGTGCAGAGTTTATATTTAGCTAAACTGTTATGTTAATTAAGAAATGCATAA >In-frame_ENAH_ENST00000366844_chr1_225840388_-_LIN9_ENST00000481685_chr1_226438620_-_1325nt GGTTCCTCGCGGCGATCCCGACTCTCCTCCCGCGGCTGCAGCAGCTGCCGGTTGCACACGGCCTCGGCGGCGGCGCGGCGAGCGCGGGCC TGTGGAGCGGCGGCCGGGCGCGCGGCCCCGGCGGGCACCCCTCAGAGGGCGGCCGAGGAAGCTCCGGGAGGAGGAGCAGGACCACGAGGA GGTGGGAGGCGGCGGCCGCCTGGGGACCAGCTCCGCGCCTCGGCCTCTCCGCCCCCTCCCCAGCCTTTCTCTCGCCCTCTTCTCCCACAC TCCCGGCCGGCGCCTCGGCTTTGTGCGAGGAGATGGTGTAGCCCCCTGGCCGCCGAAGGAGGAGCCGGACACTTGTCTCCCGTCTCCGAG CTGCTCCCCACCCCTGGAGGAGAGACCCCCCCCTCGGCTCGGCGCCTTCTGCGTCTCCCGGCTGGTGGGGAAGCCTCTGCGCCGCCGGCA CCATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAA ATCATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAA AGTTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAG GTGTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAAT TTCCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTC ATTAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGGTAATTCGTTAGGTATACTCTAATCATTTTAATGTGAAGTTCATAGTA ATTTTCAGTCCAGGTTTTAAGAATTATGCATATTTGTGAAGTACTCATATATTATTATCCGTTAAATATATTTGTAAGAGCTTTTCACTT ATATCCAGCCTATGGACAGAATAGAAATTTCACATGGATTTTGTATATAAAGAAATCAGGACATATATTTAGGTTTGGGGTCAGCATGGA GGTTGAGCTTAGAGGTAGAGCTTCCCCAGTCAGTGAGAGACTCATCTTCTCCTTCCAGCCCCCCGTGGCTCCTTTGCTTCTTTAGAGCAT >In-frame_ENAH_ENST00000366843_chr1_225840388_-_LIN9_ENST00000328205_chr1_226438620_-_2295nt CGGCGGCCGGGCGCGCGGCCCCGGCGGGCACCCCTCAGAGGGCGGCCGAGGAAGCTCCGGGAGGAGGAGCAGGACCACGAGGAGGTGGGA GGCGGCGGCCGCCTGGGGACCAGCTCCGCGCCTCGGCCTCTCCGCCCCCTCCCCAGCCTTTCTCTCGCCCTCTTCTCCCACACTCCCGGC CGGCGCCTCGGCTTTGTGCGAGGAGATGGTGTAGCCCCCTGGCCGCCGAAGGAGGAGCCGGACACTTGTCTCCCGTCTCCGAGCTGCTCC CCACCCCTGGAGGAGAGACCCCCCCCTCGGCTCGGCGCCTTCTGCGTCTCCCGGCTGGTGGGGAAGCCTCTGCGCCGCCGGCACCATGAG ACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAATCATAT TCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAGTTTTG CATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGTGTGAG GAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTTCCAGG CTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCATTAAAT GATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAATCCATGTTGCACATATTCAGAGTGGCCTGAGC CAGATGGGAAACTTACATGCCTTTGCAGCAAATAACACCAACAGAGACTGAGTAAAGATTTCATTATTCCAACTGCACGGGACATTGTTT TTGAGAAGTTCTTTTCCTTTATATAGGCTTCCAACACCAAATAACCTAACTGCTGGAAAACAAGGGAAATTTAAATCTCCAAATAAGGCA TTTTAATAGACTGTACTGCTTCTTAAACCAGCATTGCTGACCAGCATTATATTTATTTTTCTTTTATTATTCAGATGCAGTAGCATTGCT TATGTTACATATGTTTATATTCACAAATATTTTTAAACTGAAATATCTGAACATAATATAATTTCGTGGAAGAATACATTGACCATTTTT TTTAATGTGCATGAATTCACCGCAACACATGCAGACAACTGCTGCAATGGAGAGTATGAAGAAACCTGGTCTTTTTATTCATGTCGGTGG CAGTGTGGAAATTCCATCCAGAAAATTACAACTCCACTTGATTTAGTTGATCACCATCTCAGTCTTCAAAAGATAACATCATGAGGTGTG GGAAGTCCTAGTTTTAAGGAAACCACTGAAATATAGATGGGAAATGTGGACTTTACAAGTATATGTTATATATACTTGCAATGTGACATG GTTCTGTAGATCATTTTATAATAATAAATATTTTAATTTATCATAACATATAAAAGAAACCTTTGTTGTTTGTTGAAAGAAAATGAAGGA ACAGGGGGAAAAAAGGTGCAAAATGCTAAATTTCTAAAAATGGATTTGGCATGTCTTCCCATCAGTTCAGGTCAAAAGTGCATTGTTGTG AGATTTATTAAAAAAAAAATGATAACACACTATTTTCATATTTTTTTGTTTATTTGCACAACTTTTAAACCAGATTACTGGTTAAAATCC AACAGTACACAATTTATAAAGTAAAAAGATTTTATAAGGAAAACAAATATAATAACCAGTGCTGTGAAATGCAGAAGAAAGGCTTGTTTT GGTTGTTTTTCTTTTTTAGGAAAACGCTGCCTAAAATGTTAATCTTGTAAAAAGTATGTATTTGGAATTTTCTTCGTTTTAATAGAATAT TATAAACTCAAAATATAAATTTTTTTCAAATTTGGAGTTTAAGATATAGCTGTAGAGGTGGTTTTAATTCCTTTAGATGTCTCATAAAAT GAGACTTTTTATATGTTAATGTATAATAAAACTGAAACAAGATTATTTTCCATTTGAAATTTTTGTATAGTTTAAAAAGGCTTCCGTATT CTTTGTTGGTATTGTGCCACTGCAGAACTTTAGTGCAGAGTTTATATTTAGCTAAACTGTTATGTTAATTAAGAAATGCATAAATCTTCT >In-frame_ENAH_ENST00000366843_chr1_225840388_-_LIN9_ENST00000366801_chr1_226438620_-_2288nt CGGCGGCCGGGCGCGCGGCCCCGGCGGGCACCCCTCAGAGGGCGGCCGAGGAAGCTCCGGGAGGAGGAGCAGGACCACGAGGAGGTGGGA GGCGGCGGCCGCCTGGGGACCAGCTCCGCGCCTCGGCCTCTCCGCCCCCTCCCCAGCCTTTCTCTCGCCCTCTTCTCCCACACTCCCGGC CGGCGCCTCGGCTTTGTGCGAGGAGATGGTGTAGCCCCCTGGCCGCCGAAGGAGGAGCCGGACACTTGTCTCCCGTCTCCGAGCTGCTCC CCACCCCTGGAGGAGAGACCCCCCCCTCGGCTCGGCGCCTTCTGCGTCTCCCGGCTGGTGGGGAAGCCTCTGCGCCGCCGGCACCATGAG ACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAATCATAT TCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAGTTTTG CATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGTGTGAG GAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTTCCAGG CTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCATTAAAT GATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAATCCATGTTGCACATATTCAGAGTGGCCTGAGC CAGATGGGAAACTTACATGCCTTTGCAGCAAATAACACCAACAGAGACTGAGTAAAGATTTCATTATTCCAACTGCACGGGACATTGTTT TTGAGAAGTTCTTTTCCTTTATATAGGCTTCCAACACCAAATAACCTAACTGCTGGAAAACAAGGGAAATTTAAATCTCCAAATAAGGCA TTTTAATAGACTGTACTGCTTCTTAAACCAGCATTGCTGACCAGCATTATATTTATTTTTCTTTTATTATTCAGATGCAGTAGCATTGCT TATGTTACATATGTTTATATTCACAAATATTTTTAAACTGAAATATCTGAACATAATATAATTTCGTGGAAGAATACATTGACCATTTTT TTTAATGTGCATGAATTCACCGCAACACATGCAGACAACTGCTGCAATGGAGAGTATGAAGAAACCTGGTCTTTTTATTCATGTCGGTGG CAGTGTGGAAATTCCATCCAGAAAATTACAACTCCACTTGATTTAGTTGATCACCATCTCAGTCTTCAAAAGATAACATCATGAGGTGTG GGAAGTCCTAGTTTTAAGGAAACCACTGAAATATAGATGGGAAATGTGGACTTTACAAGTATATGTTATATATACTTGCAATGTGACATG GTTCTGTAGATCATTTTATAATAATAAATATTTTAATTTATCATAACATATAAAAGAAACCTTTGTTGTTTGTTGAAAGAAAATGAAGGA ACAGGGGGAAAAAAGGTGCAAAATGCTAAATTTCTAAAAATGGATTTGGCATGTCTTCCCATCAGTTCAGGTCAAAAGTGCATTGTTGTG AGATTTATTAAAAAAAAAATGATAACACACTATTTTCATATTTTTTTGTTTATTTGCACAACTTTTAAACCAGATTACTGGTTAAAATCC AACAGTACACAATTTATAAAGTAAAAAGATTTTATAAGGAAAACAAATATAATAACCAGTGCTGTGAAATGCAGAAGAAAGGCTTGTTTT GGTTGTTTTTCTTTTTTAGGAAAACGCTGCCTAAAATGTTAATCTTGTAAAAAGTATGTATTTGGAATTTTCTTCGTTTTAATAGAATAT TATAAACTCAAAATATAAATTTTTTTCAAATTTGGAGTTTAAGATATAGCTGTAGAGGTGGTTTTAATTCCTTTAGATGTCTCATAAAAT GAGACTTTTTATATGTTAATGTATAATAAAACTGAAACAAGATTATTTTCCATTTGAAATTTTTGTATAGTTTAAAAAGGCTTCCGTATT CTTTGTTGGTATTGTGCCACTGCAGAACTTTAGTGCAGAGTTTATATTTAGCTAAACTGTTATGTTAATTAAGAAATGCATAAATCTTCT >In-frame_ENAH_ENST00000366843_chr1_225840388_-_LIN9_ENST00000481685_chr1_226438620_-_1228nt CGGCGGCCGGGCGCGCGGCCCCGGCGGGCACCCCTCAGAGGGCGGCCGAGGAAGCTCCGGGAGGAGGAGCAGGACCACGAGGAGGTGGGA GGCGGCGGCCGCCTGGGGACCAGCTCCGCGCCTCGGCCTCTCCGCCCCCTCCCCAGCCTTTCTCTCGCCCTCTTCTCCCACACTCCCGGC CGGCGCCTCGGCTTTGTGCGAGGAGATGGTGTAGCCCCCTGGCCGCCGAAGGAGGAGCCGGACACTTGTCTCCCGTCTCCGAGCTGCTCC CCACCCCTGGAGGAGAGACCCCCCCCTCGGCTCGGCGCCTTCTGCGTCTCCCGGCTGGTGGGGAAGCCTCTGCGCCGCCGGCACCATGAG ACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAATGAACACAGAAGCAGAAAAATTGAAATCATAT TCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGAACAGCTGAACAAGGACCTAAACAAAGTTTTG CATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGATCAGCCAACAGATATGAGACGCAGGTGTGAG GAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGAAAATGAAAATCTGACAGACTTAATTTCCAGG CTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTTTGAATTCAAATCACTTACAGACTCATTAAAT GATATCAAGAGTACAATAGACGCTTCTAATATCAGGTAATTCGTTAGGTATACTCTAATCATTTTAATGTGAAGTTCATAGTAATTTTCA GTCCAGGTTTTAAGAATTATGCATATTTGTGAAGTACTCATATATTATTATCCGTTAAATATATTTGTAAGAGCTTTTCACTTATATCCA GCCTATGGACAGAATAGAAATTTCACATGGATTTTGTATATAAAGAAATCAGGACATATATTTAGGTTTGGGGTCAGCATGGAGGTTGAG CTTAGAGGTAGAGCTTCCCCAGTCAGTGAGAGACTCATCTTCTCCTTCCAGCCCCCCGTGGCTCCTTTGCTTCTTTAGAGCATATTTGTT >In-frame_ENAH_ENST00000284563_chr1_225840388_-_LIN9_ENST00000328205_chr1_226438620_-_1966nt GGGGAAGCCTCTGCGCCGCCGGCACCATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAAT GAACACAGAAGCAGAAAAATTGAAATCATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGA ACAGCTGAACAAGGACCTAAACAAAGTTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGA TCAGCCAACAGATATGAGACGCAGGTGTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGA AAATGAAAATCTGACAGACTTAATTTCCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTT TGAATTCAAATCACTTACAGACTCATTAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAAT CCATGTTGCACATATTCAGAGTGGCCTGAGCCAGATGGGAAACTTACATGCCTTTGCAGCAAATAACACCAACAGAGACTGAGTAAAGAT TTCATTATTCCAACTGCACGGGACATTGTTTTTGAGAAGTTCTTTTCCTTTATATAGGCTTCCAACACCAAATAACCTAACTGCTGGAAA ACAAGGGAAATTTAAATCTCCAAATAAGGCATTTTAATAGACTGTACTGCTTCTTAAACCAGCATTGCTGACCAGCATTATATTTATTTT TCTTTTATTATTCAGATGCAGTAGCATTGCTTATGTTACATATGTTTATATTCACAAATATTTTTAAACTGAAATATCTGAACATAATAT AATTTCGTGGAAGAATACATTGACCATTTTTTTTAATGTGCATGAATTCACCGCAACACATGCAGACAACTGCTGCAATGGAGAGTATGA AGAAACCTGGTCTTTTTATTCATGTCGGTGGCAGTGTGGAAATTCCATCCAGAAAATTACAACTCCACTTGATTTAGTTGATCACCATCT CAGTCTTCAAAAGATAACATCATGAGGTGTGGGAAGTCCTAGTTTTAAGGAAACCACTGAAATATAGATGGGAAATGTGGACTTTACAAG TATATGTTATATATACTTGCAATGTGACATGGTTCTGTAGATCATTTTATAATAATAAATATTTTAATTTATCATAACATATAAAAGAAA CCTTTGTTGTTTGTTGAAAGAAAATGAAGGAACAGGGGGAAAAAAGGTGCAAAATGCTAAATTTCTAAAAATGGATTTGGCATGTCTTCC CATCAGTTCAGGTCAAAAGTGCATTGTTGTGAGATTTATTAAAAAAAAAATGATAACACACTATTTTCATATTTTTTTGTTTATTTGCAC AACTTTTAAACCAGATTACTGGTTAAAATCCAACAGTACACAATTTATAAAGTAAAAAGATTTTATAAGGAAAACAAATATAATAACCAG TGCTGTGAAATGCAGAAGAAAGGCTTGTTTTGGTTGTTTTTCTTTTTTAGGAAAACGCTGCCTAAAATGTTAATCTTGTAAAAAGTATGT ATTTGGAATTTTCTTCGTTTTAATAGAATATTATAAACTCAAAATATAAATTTTTTTCAAATTTGGAGTTTAAGATATAGCTGTAGAGGT GGTTTTAATTCCTTTAGATGTCTCATAAAATGAGACTTTTTATATGTTAATGTATAATAAAACTGAAACAAGATTATTTTCCATTTGAAA TTTTTGTATAGTTTAAAAAGGCTTCCGTATTCTTTGTTGGTATTGTGCCACTGCAGAACTTTAGTGCAGAGTTTATATTTAGCTAAACTG >In-frame_ENAH_ENST00000284563_chr1_225840388_-_LIN9_ENST00000366801_chr1_226438620_-_1959nt GGGGAAGCCTCTGCGCCGCCGGCACCATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAAT GAACACAGAAGCAGAAAAATTGAAATCATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGA ACAGCTGAACAAGGACCTAAACAAAGTTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGA TCAGCCAACAGATATGAGACGCAGGTGTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGA AAATGAAAATCTGACAGACTTAATTTCCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTT TGAATTCAAATCACTTACAGACTCATTAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGTTGCTTTCAGAATAATGTAGAAAT CCATGTTGCACATATTCAGAGTGGCCTGAGCCAGATGGGAAACTTACATGCCTTTGCAGCAAATAACACCAACAGAGACTGAGTAAAGAT TTCATTATTCCAACTGCACGGGACATTGTTTTTGAGAAGTTCTTTTCCTTTATATAGGCTTCCAACACCAAATAACCTAACTGCTGGAAA ACAAGGGAAATTTAAATCTCCAAATAAGGCATTTTAATAGACTGTACTGCTTCTTAAACCAGCATTGCTGACCAGCATTATATTTATTTT TCTTTTATTATTCAGATGCAGTAGCATTGCTTATGTTACATATGTTTATATTCACAAATATTTTTAAACTGAAATATCTGAACATAATAT AATTTCGTGGAAGAATACATTGACCATTTTTTTTAATGTGCATGAATTCACCGCAACACATGCAGACAACTGCTGCAATGGAGAGTATGA AGAAACCTGGTCTTTTTATTCATGTCGGTGGCAGTGTGGAAATTCCATCCAGAAAATTACAACTCCACTTGATTTAGTTGATCACCATCT CAGTCTTCAAAAGATAACATCATGAGGTGTGGGAAGTCCTAGTTTTAAGGAAACCACTGAAATATAGATGGGAAATGTGGACTTTACAAG TATATGTTATATATACTTGCAATGTGACATGGTTCTGTAGATCATTTTATAATAATAAATATTTTAATTTATCATAACATATAAAAGAAA CCTTTGTTGTTTGTTGAAAGAAAATGAAGGAACAGGGGGAAAAAAGGTGCAAAATGCTAAATTTCTAAAAATGGATTTGGCATGTCTTCC CATCAGTTCAGGTCAAAAGTGCATTGTTGTGAGATTTATTAAAAAAAAAATGATAACACACTATTTTCATATTTTTTTGTTTATTTGCAC AACTTTTAAACCAGATTACTGGTTAAAATCCAACAGTACACAATTTATAAAGTAAAAAGATTTTATAAGGAAAACAAATATAATAACCAG TGCTGTGAAATGCAGAAGAAAGGCTTGTTTTGGTTGTTTTTCTTTTTTAGGAAAACGCTGCCTAAAATGTTAATCTTGTAAAAAGTATGT ATTTGGAATTTTCTTCGTTTTAATAGAATATTATAAACTCAAAATATAAATTTTTTTCAAATTTGGAGTTTAAGATATAGCTGTAGAGGT GGTTTTAATTCCTTTAGATGTCTCATAAAATGAGACTTTTTATATGTTAATGTATAATAAAACTGAAACAAGATTATTTTCCATTTGAAA TTTTTGTATAGTTTAAAAAGGCTTCCGTATTCTTTGTTGGTATTGTGCCACTGCAGAACTTTAGTGCAGAGTTTATATTTAGCTAAACTG >In-frame_ENAH_ENST00000284563_chr1_225840388_-_LIN9_ENST00000481685_chr1_226438620_-_899nt GGGGAAGCCTCTGCGCCGCCGGCACCATGAGACCAGATTATCAAAAATTCTCATGATTAAAAAGGAACATATCAAGAAATTAAGGGAAAT GAACACAGAAGCAGAAAAATTGAAATCATATTCCATGCCCATCAGCATTGAATTTCAGCGGAGATATGCAACAATTGTTCTGGAGCTTGA ACAGCTGAACAAGGACCTAAACAAAGTTTTGCATAAAGTTCAACAGTATTGCTATGAGCTTGCTCCAGACCAGGGGCTCCAGCCTGCAGA TCAGCCAACAGATATGAGACGCAGGTGTGAGGAAGAAGCACAGGAAATTGTTCGGCATGCAAATTCCTCAACAGGACAGCCCTGCGTTGA AAATGAAAATCTGACAGACTTAATTTCCAGGCTTACAGCTATTTTGTTACAAATTAAGTGTCTAGCAGAAGGAGGAGACCTGAATTCCTT TGAATTCAAATCACTTACAGACTCATTAAATGATATCAAGAGTACAATAGACGCTTCTAATATCAGGTAATTCGTTAGGTATACTCTAAT CATTTTAATGTGAAGTTCATAGTAATTTTCAGTCCAGGTTTTAAGAATTATGCATATTTGTGAAGTACTCATATATTATTATCCGTTAAA TATATTTGTAAGAGCTTTTCACTTATATCCAGCCTATGGACAGAATAGAAATTTCACATGGATTTTGTATATAAAGAAATCAGGACATAT ATTTAGGTTTGGGGTCAGCATGGAGGTTGAGCTTAGAGGTAGAGCTTCCCCAGTCAGTGAGAGACTCATCTTCTCCTTCCAGCCCCCCGT |
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FusionGenePPI for ENAH_LIN9 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ENAH | ABI1, RAPH1, XPO6, DNMBP, TES, ZYX, BAIAP2, PFN1, ELAVL1, TERF2IP, MAPK1, DYRK1B, HECW2, APBB1, SEPT7, COPS4, PPP6R3, TRIM28, WWOX, SMURF2, XIRP1, LGALS3BP, TP53, ABI2, ABI3, PRMT6, PARL, VASP, PVRL4, EVL, NTRK1, FGFR1OP, XPO1, PRPF4, TACC3, SNW1, CDC5L, ATOH1, RAC1, YAP1, GPHN, PPM1K, TPTE, PFN2, TMOD3, BCHE, DCAF7, TRIM25 | LIN9 | RB1, LIN54, LIN37, LIN52, MYBL2, E2F4, RBL2, TFDP1, TFDP2, LIN9, MYBL1, RBBP4, RBL1, SHMT2, MOV10, NXF1, PHF20L1, RBBP7, HIST1H2BG, XPO1, TEAD2, FOXM1, DIS3L, FAM167A, RGS13, SLMAP, RPN2, COL1A1, TCF19, HBS1L, MOCS3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ENAH_LIN9 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ENAH_LIN9 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ENAH | C0023467 | Leukemia, Myelocytic, Acute | 1 | CTD_human |
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