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Fusion gene ID: 11384 |
FusionGeneSummary for ELAC2_COX10 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ELAC2_COX10 | Fusion gene ID: 11384 | Hgene | Tgene | Gene symbol | ELAC2 | COX10 | Gene ID | 60528 | 1352 |
| Gene name | elaC ribonuclease Z 2 | COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor | |
| Synonyms | COXPD17|ELC2|HPC2 | - | |
| Cytomap | 17p12 | 17p12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc phosphodiesterase ELAC protein 2RNase Z 2elaC homolog 2elaC homolog protein 2elaC-like protein 2heredity prostate cancer protein 2putative prostate cancer susceptibility protein HPC2/ELAC2ribonuclease Z 2tRNA 3 endonuclease 2tRNase Z (long f | protoheme IX farnesyltransferase, mitochondrialCOX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferasecytochrome c oxidase assembly homolog 10cytochrome c oxidase assembly proteincytochrome c oxidase subunit Xheme A: farnesy | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9BQ52 | Q12887 | |
| Ensembl transtripts involved in fusion gene | ENST00000338034, ENST00000395962, ENST00000426905, ENST00000609345, ENST00000578071, | ENST00000261643, ENST00000536205, ENST00000537334, ENST00000429152, | |
| Fusion gene scores | * DoF score | 2 X 3 X 2=12 | 1 X 1 X 1=1 |
| # samples | 2 | 1 | |
| ** MAII score | log2(2/12*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ELAC2 [Title/Abstract] AND COX10 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-HC-7213-01A | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000338034 | ENST00000261643 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| In-frame | ENST00000338034 | ENST00000536205 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5CDS-5UTR | ENST00000338034 | ENST00000537334 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5CDS-intron | ENST00000338034 | ENST00000429152 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| In-frame | ENST00000395962 | ENST00000261643 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| In-frame | ENST00000395962 | ENST00000536205 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5CDS-5UTR | ENST00000395962 | ENST00000537334 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5CDS-intron | ENST00000395962 | ENST00000429152 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| In-frame | ENST00000426905 | ENST00000261643 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| In-frame | ENST00000426905 | ENST00000536205 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5CDS-5UTR | ENST00000426905 | ENST00000537334 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5CDS-intron | ENST00000426905 | ENST00000429152 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5UTR-3CDS | ENST00000609345 | ENST00000261643 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5UTR-3CDS | ENST00000609345 | ENST00000536205 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5UTR-5UTR | ENST00000609345 | ENST00000537334 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5UTR-intron | ENST00000609345 | ENST00000429152 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| Frame-shift | ENST00000578071 | ENST00000261643 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| Frame-shift | ENST00000578071 | ENST00000536205 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5CDS-5UTR | ENST00000578071 | ENST00000537334 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
| 5CDS-intron | ENST00000578071 | ENST00000429152 | ELAC2 | chr17 | 12919085 | - | COX10 | chr17 | 14063194 | + |
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FusionProtFeatures for ELAC2_COX10 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ELAC2 | COX10 |
| Zinc phosphodiesterase, which displays mitochondrialtRNA 3'-processing endonuclease activity. Involved in tRNAmaturation, by removing a 3'-trailer from precursor tRNA.{ECO:0000269|PubMed:21593607}. | Converts protoheme IX and farnesyl diphosphate to hemeO. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >COX10 | chr17:12919085 | chr17:14063194 | ENST00000261643 | + | 3 | 7 | 235_255 | 208 | 444 | Transmembrane | Helical |
| Tgene | >COX10 | chr17:12919085 | chr17:14063194 | ENST00000261643 | + | 3 | 7 | 257_277 | 208 | 444 | Transmembrane | Helical |
| Tgene | >COX10 | chr17:12919085 | chr17:14063194 | ENST00000261643 | + | 3 | 7 | 280_300 | 208 | 444 | Transmembrane | Helical |
| Tgene | >COX10 | chr17:12919085 | chr17:14063194 | ENST00000261643 | + | 3 | 7 | 309_329 | 208 | 444 | Transmembrane | Helical |
| Tgene | >COX10 | chr17:12919085 | chr17:14063194 | ENST00000261643 | + | 3 | 7 | 364_384 | 208 | 444 | Transmembrane | Helical |
| Tgene | >COX10 | chr17:12919085 | chr17:14063194 | ENST00000261643 | + | 3 | 7 | 411_431 | 208 | 444 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | COX10 | chr17:12919085 | chr17:14063194 | ENST00000261643 | + | 3 | 7 | 174_194 | 208 | 444 | Transmembrane | Helical |
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FusionGeneSequence for ELAC2_COX10 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ELAC2_ENST00000338034_chr17_12919085_-_COX10_ENST00000261643_chr17_14063194_+_380aa MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL >In-frame_ELAC2_ENST00000338034_chr17_12919085_-_COX10_ENST00000536205_chr17_14063194_+_380aa MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL >In-frame_ELAC2_ENST00000395962_chr17_12919085_-_COX10_ENST00000261643_chr17_14063194_+_361aa MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGVQRLMQEHKLKVARLDNIF LTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGVNPLTGALG LFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLC RRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLLLMLTCKRPSGGGDAGPPPS >In-frame_ELAC2_ENST00000395962_chr17_12919085_-_COX10_ENST00000536205_chr17_14063194_+_361aa MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGVQRLMQEHKLKVARLDNIF LTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCAVPGVAILTLGVNPLTGALG LFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLC RRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLLLMLTCKRPSGGGDAGPPPS >In-frame_ELAC2_ENST00000426905_chr17_12919085_-_COX10_ENST00000261643_chr17_14063194_+_380aa MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL >In-frame_ELAC2_ENST00000426905_chr17_12919085_-_COX10_ENST00000536205_chr17_14063194_+_380aa MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEG VQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFATCCA VPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLR EDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ELAC2_ENST00000338034_chr17_12919085_-_COX10_ENST00000261643_chr17_14063194_+_1140nt ATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAG CGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTG CAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGC GTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGC TTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTT GACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCT GTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTAC ACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACG GGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGT GAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTG CTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTAC CTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTG >In-frame_ELAC2_ENST00000338034_chr17_12919085_-_COX10_ENST00000536205_chr17_14063194_+_1140nt ATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAG CGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTG CAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGC GTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGC TTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTT GACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCT GTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTAC ACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACG GGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGT GAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTG CTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTAC CTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTG >In-frame_ELAC2_ENST00000395962_chr17_12919085_-_COX10_ENST00000261643_chr17_14063194_+_1083nt ATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAG CGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTG CAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTC CTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCT GGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCA TTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGG CTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCC ATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTT CCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGC CGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATC ATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTC TGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGACGCAGGGCCCCCTCCCAGC >In-frame_ELAC2_ENST00000395962_chr17_12919085_-_COX10_ENST00000536205_chr17_14063194_+_1083nt ATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAG CGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTG CAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTC CTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCT GGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCA TTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGG CTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCC ATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTT CCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGC CGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATC ATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTC TGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGACGCAGGGCCCCCTCCCAGC >In-frame_ELAC2_ENST00000426905_chr17_12919085_-_COX10_ENST00000261643_chr17_14063194_+_1140nt ATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAG CGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTG CAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGC GTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGC TTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTT GACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCT GTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTAC ACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACG GGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGT GAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTG CTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTAC CTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTG >In-frame_ELAC2_ENST00000426905_chr17_12919085_-_COX10_ENST00000536205_chr17_14063194_+_1140nt ATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAG CGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTG CAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGC GTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGC TTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTT GACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCT GTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTAC ACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACG GGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGT GAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTG CTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTAC CTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ELAC2_ENST00000338034_chr17_12919085_-_COX10_ENST00000261643_chr17_14063194_+_2844nt AGAACTAGGGGCGGGGCCGCTTGAGACGCTCTAGTATTCCTCTACTCTATGGCCACTGTCAATTGACAAGTCCCGAGCGGTAAAGCTCCT TTCTATTGGATGAGCAGCCTCGCGTAGGCGGGAAGCTCGGTGCACGGCGCGCTGATTGGCTGGATCCGCCATGCGGAGCGGCTAGGTGGT GCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCC GCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTG CGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCG GGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTA AAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAA ACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGA CCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGG GTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAAC ACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTG GGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATG ATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTG GACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGAC CGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGA GGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAAT TCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTT TTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTC TTTATACATCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTTCCTCCTCACATGGGGGTACACATACACAGCTTCCTCTTTTGGTTCCA TCCTTACCACCACACCACACGCACACTCCACATGCCCAGCAGAGTGGCACTTGGTGGCCAGAAAGTGTGAGCCTCATGATCTGCTGTCTG TAGTTCTGTGAGCTCAGGTCCCTCAAAGGCCTCGGAGCACCCCCTTCCTGGTGACTGAGCCAGGGCCTGCATTTTTGGTTTTCCCCACCC CACACATTCTCAACCATAGTCCTTCTAACAATACCAATAGCTAGGACCCGGCTGCTGTGCACTGGGACTGGGGATTCCACATGTTTGCCT TGGGAGTCTCAAGCTGGACTGCCAGCCCCTGTCCTCCCTTCACCCCCATTGCGTATGAGCATTTCAGAACTCCAAGGAGTCACAGGCATC TTTATAGTTCACGTTAACATATAGACACTGTTGGAAGCAGTTCCTTCTAAAAGGGTAGCCCTGGACTTAATACCAGCCGGATACCTCTGG CCCCCACCCCATTACTGTACCTCTGGAGTCACTACTGTGGGTCGCCACTCCTCTGCTACACAGCACGGCTTTTTCAAGGCTGTATTGAGA AGGGAAGTTAGGAAGAAGGGTGTGCTGGGCTAACCAGCCCACAGAGCTCACATTCCTGTCCCTTGGGTGAAAAATACATGTCCATCCTGA TATCTCCTGAATTCAGAAATTAGCCTCCACATGTGCAATGGCTTTAAGAGCCAGAAGCAGGGTTCTGGGAATTTTGCAAGTTATCCTGTG GCCAGGTGTGGTCTCGGTTACCAAATACGGTTACCTGCAGCTTTTTAGTCCTTTGTGCTCCCACGGGTCTGCAGAGTCCCATCTGCCCAA AGGTCTTGAAGCTTGACAGGATGTTTTCATTACTCAGTCTCCCAGGGCACTGCTGGTCCGTAGGGATTCATTGGTCGGGGTGGGAGAGTT AAACAACATTTAAACAGAGTTCTCTCAAAAATGTCTAAAGGGATTGTAGGTAGATAACATCCAATCACTGTTTGCACTTATCTGAAATCT TCCCTCTTGGCTGCCCCCAGGTATTTACTGTGGAGAACATTGCATAGGAATGTCTGGAAAAAGCCTCTACAACTTGTTACAGCCTTCACA >In-frame_ELAC2_ENST00000338034_chr17_12919085_-_COX10_ENST00000536205_chr17_14063194_+_1680nt AGAACTAGGGGCGGGGCCGCTTGAGACGCTCTAGTATTCCTCTACTCTATGGCCACTGTCAATTGACAAGTCCCGAGCGGTAAAGCTCCT TTCTATTGGATGAGCAGCCTCGCGTAGGCGGGAAGCTCGGTGCACGGCGCGCTGATTGGCTGGATCCGCCATGCGGAGCGGCTAGGTGGT GCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCC GCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTG CGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCG GGCGCCGCGCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTA AAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAA ACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGA CCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGG GTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAAC ACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTG GGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATG ATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTG GACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGAC CGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGA GGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAAT TCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTT TTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTC >In-frame_ELAC2_ENST00000395962_chr17_12919085_-_COX10_ENST00000261643_chr17_14063194_+_2621nt AGCGGCTAGGTGGTGCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCT CGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACC CGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGG GTAGCCGGGACTCGGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACT GGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGT TTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCT TTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCC TGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGG GCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCC TGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGC GCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCA ATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACC TGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACG CCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATT ATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAG CTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACATCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTT CCTCCTCACATGGGGGTACACATACACAGCTTCCTCTTTTGGTTCCATCCTTACCACCACACCACACGCACACTCCACATGCCCAGCAGA GTGGCACTTGGTGGCCAGAAAGTGTGAGCCTCATGATCTGCTGTCTGTAGTTCTGTGAGCTCAGGTCCCTCAAAGGCCTCGGAGCACCCC CTTCCTGGTGACTGAGCCAGGGCCTGCATTTTTGGTTTTCCCCACCCCACACATTCTCAACCATAGTCCTTCTAACAATACCAATAGCTA GGACCCGGCTGCTGTGCACTGGGACTGGGGATTCCACATGTTTGCCTTGGGAGTCTCAAGCTGGACTGCCAGCCCCTGTCCTCCCTTCAC CCCCATTGCGTATGAGCATTTCAGAACTCCAAGGAGTCACAGGCATCTTTATAGTTCACGTTAACATATAGACACTGTTGGAAGCAGTTC CTTCTAAAAGGGTAGCCCTGGACTTAATACCAGCCGGATACCTCTGGCCCCCACCCCATTACTGTACCTCTGGAGTCACTACTGTGGGTC GCCACTCCTCTGCTACACAGCACGGCTTTTTCAAGGCTGTATTGAGAAGGGAAGTTAGGAAGAAGGGTGTGCTGGGCTAACCAGCCCACA GAGCTCACATTCCTGTCCCTTGGGTGAAAAATACATGTCCATCCTGATATCTCCTGAATTCAGAAATTAGCCTCCACATGTGCAATGGCT TTAAGAGCCAGAAGCAGGGTTCTGGGAATTTTGCAAGTTATCCTGTGGCCAGGTGTGGTCTCGGTTACCAAATACGGTTACCTGCAGCTT TTTAGTCCTTTGTGCTCCCACGGGTCTGCAGAGTCCCATCTGCCCAAAGGTCTTGAAGCTTGACAGGATGTTTTCATTACTCAGTCTCCC AGGGCACTGCTGGTCCGTAGGGATTCATTGGTCGGGGTGGGAGAGTTAAACAACATTTAAACAGAGTTCTCTCAAAAATGTCTAAAGGGA TTGTAGGTAGATAACATCCAATCACTGTTTGCACTTATCTGAAATCTTCCCTCTTGGCTGCCCCCAGGTATTTACTGTGGAGAACATTGC ATAGGAATGTCTGGAAAAAGCCTCTACAACTTGTTACAGCCTTCACATTTGTACAATTCATTGATTCTCTTTTCCTTCCACAATAAAATG >In-frame_ELAC2_ENST00000395962_chr17_12919085_-_COX10_ENST00000536205_chr17_14063194_+_1457nt AGCGGCTAGGTGGTGCACGGGAAACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCT CGCTGCTGCGGTCCGCGGCCGGACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACC CGCTGCGGCACCTGCGCACGCGAGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGG GTAGCCGGGACTCGGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGCTCGCCTGGACAACATATTCCTGACACGAATGCACT GGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCTTCCAAAGTGTGTACTTTCTGGACCTCCACAACTGT TTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGTTCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCT TTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCCACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCC TGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGTCGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGG GCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAATCCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCC TGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGTCACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGC GCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCACCACATGGACCTTCCCCATCATGGCCCTTCCCATCA ATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAGCTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACC TGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGACGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACG CCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAACACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATT ATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATATTACCCAAAATGCTCCCCAAATAAGAAATGCATCAG CTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACATCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTT >In-frame_ELAC2_ENST00000426905_chr17_12919085_-_COX10_ENST00000261643_chr17_14063194_+_2656nt AACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGG ACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCG AGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGC GCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGC TCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCT TCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT TCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCC ACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGT CGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAAT CCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGT CACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCAC CACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAG CTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGA CGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAAC ACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATAT TACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACA TCTCTCCTCCAACCCCACCCTCTATTCTGTTTCTTCCTCCTCACATGGGGGTACACATACACAGCTTCCTCTTTTGGTTCCATCCTTACC ACCACACCACACGCACACTCCACATGCCCAGCAGAGTGGCACTTGGTGGCCAGAAAGTGTGAGCCTCATGATCTGCTGTCTGTAGTTCTG TGAGCTCAGGTCCCTCAAAGGCCTCGGAGCACCCCCTTCCTGGTGACTGAGCCAGGGCCTGCATTTTTGGTTTTCCCCACCCCACACATT CTCAACCATAGTCCTTCTAACAATACCAATAGCTAGGACCCGGCTGCTGTGCACTGGGACTGGGGATTCCACATGTTTGCCTTGGGAGTC TCAAGCTGGACTGCCAGCCCCTGTCCTCCCTTCACCCCCATTGCGTATGAGCATTTCAGAACTCCAAGGAGTCACAGGCATCTTTATAGT TCACGTTAACATATAGACACTGTTGGAAGCAGTTCCTTCTAAAAGGGTAGCCCTGGACTTAATACCAGCCGGATACCTCTGGCCCCCACC CCATTACTGTACCTCTGGAGTCACTACTGTGGGTCGCCACTCCTCTGCTACACAGCACGGCTTTTTCAAGGCTGTATTGAGAAGGGAAGT TAGGAAGAAGGGTGTGCTGGGCTAACCAGCCCACAGAGCTCACATTCCTGTCCCTTGGGTGAAAAATACATGTCCATCCTGATATCTCCT GAATTCAGAAATTAGCCTCCACATGTGCAATGGCTTTAAGAGCCAGAAGCAGGGTTCTGGGAATTTTGCAAGTTATCCTGTGGCCAGGTG TGGTCTCGGTTACCAAATACGGTTACCTGCAGCTTTTTAGTCCTTTGTGCTCCCACGGGTCTGCAGAGTCCCATCTGCCCAAAGGTCTTG AAGCTTGACAGGATGTTTTCATTACTCAGTCTCCCAGGGCACTGCTGGTCCGTAGGGATTCATTGGTCGGGGTGGGAGAGTTAAACAACA TTTAAACAGAGTTCTCTCAAAAATGTCTAAAGGGATTGTAGGTAGATAACATCCAATCACTGTTTGCACTTATCTGAAATCTTCCCTCTT GGCTGCCCCCAGGTATTTACTGTGGAGAACATTGCATAGGAATGTCTGGAAAAAGCCTCTACAACTTGTTACAGCCTTCACATTTGTACA >In-frame_ELAC2_ENST00000426905_chr17_12919085_-_COX10_ENST00000536205_chr17_14063194_+_1492nt AACGCGGGCGTAGGTGACCGGCGGCTTTCTCAGTTTTGGTGGAGACGGGCGCATGTGGGCGCTTTGCTCGCTGCTGCGGTCCGCGGCCGG ACGCACCATGTCGCAGGGACGCACCATATCGCAGGCACCCGCCCGCCGCGAGCGGCCGCGCAAGGACCCGCTGCGGCACCTGCGCACGCG AGAGAAGCGCGGACCGTCGGGGTGCTCCGGCGGCCCAAACACCGTGTACCTGCAGGTGGTGGCAGCGGGTAGCCGGGACTCGGGCGCCGC GCTCTACGTCTTCTCCGAGTTCAACCGGTATCTCTTCAACTGTGGAGAAGGCGTTCAGAGACTCATGCAGGAGCACAAGTTAAAGGTTGC TCGCCTGGACAACATATTCCTGACACGAATGCACTGGTCTAATGTTGGGGGCTTAAGTGGAATGATTCTTACTTTAAAGGAAACCGGGCT TCCAAAGTGTGTACTTTCTGGACCTCCACAACTGTTTTTTGAGGTGCCATTTGACTCAAACATGAATAGGACAAAGAACAGACCGCTGGT TCGTGGACAGATCAGCCCATTGCTAGCTGTGTCCTTTGCCACTTGTTGTGCTGTTCCGGGAGTTGCCATTCTGACCTTGGGGGTGAATCC ACTCACAGGAGCCCTGGGGCTCTTCAACATTTTCCTGTATACCTGCTGCTACACACCACTGAAAAGGATCAGCATTGCCAACACATGGGT CGGAGCTGTGGTTGGGGCCATCCCGCCTGTCATGGGCTGGACAGCGGCCACGGGCAGCCTCGATGCTGGCGCATTTCTCCTGGGAGGAAT CCTCTACTCCTGGCAGTTTCCTCATTTCAACGCCCTGAGCTGGGGCCTCCGTGAAGACTACTCCCGGGGCGGCTACTGCATGATGTCGGT CACCCACCCGGGCCTGTGCCGGCGCGTGGCGCTGCGCCACTGCCTGGCCCTGCTCGTGCTGTCCGCAGCAGCCCCTGTGCTGGACATCAC CACATGGACCTTCCCCATCATGGCCCTTCCCATCAATGCGTACATCTCCTACCTCGGCTTCCGCTTCTACGTGGACGCAGACCGCAGGAG CTCGCGGAGACTGTTCTTCTGCAGCCTGTGGCACCTGCCGCTGCTGCTGCTGCTCATGCTCACCTGCAAGCGGCCGAGCGGAGGCGGGGA CGCAGGGCCCCCTCCCAGCTGAGAGCACTGGGACGCCCACCGCCCCTTTCCCTCCGCTGCCAGGCGAGCATGTTGTGGTAATTCTGGAAC ACAAGAAGAGAAATTGCTGGGTTTAGAACAAGATTATAAACGAATTCGGTGCTCAGTGATCACTTGACAGTTTTTTTTTTTTTTAAATAT TACCCAAAATGCTCCCCAAATAAGAAATGCATCAGCTCAGTCAGTGAATACAAAAAAGGAATTATTTTTCCCTTTGAGGGTCTTTATACA |
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FusionGenePPI for ELAC2_COX10 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ELAC2 | PUF60, ASCC2, CUX1, COPS5, SMAD2, SMAD3, FOXH1, ARIH1, XPO5, FEN1, HARS, IPO7, NRD1, PFDN1, PPP2CB, SARS, SNX5, TNPO3, TSN, WDR4, MRPS30, C12orf10, CKAP5, DDX5, DNAJC17, EIF2D, EIF6, ATIC, FERMT2, GLRX5, GORASP2, HNRNPF, HNRNPH1, HNRNPK, HSD17B10, KIF2C, PFKM, PFKP, ZNHIT2, NTRK1, HIST1H2BG, CEP19, CAMKK1, SENP3, UBAC1, RNF123, YBEY, TRMT10C, MRPL21 | COX10 | FAM136A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ELAC2_COX10 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ELAC2_COX10 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ELAC2 | C3539120 | PROSTATE CANCER, HEREDITARY, 2 | 10 | UNIPROT |
| Hgene | ELAC2 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | ELAC2 | C3809526 | COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 17 | 1 | ORPHANET;UNIPROT |
| Tgene | COX10 | C0268237 | Cytochrome-c Oxidase Deficiency | 3 | ORPHANET;UNIPROT |
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