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Fusion gene ID: 11298 |
FusionGeneSummary for EIF3M_UEVLD |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: EIF3M_UEVLD | Fusion gene ID: 11298 | Hgene | Tgene | Gene symbol | EIF3M | UEVLD | Gene ID | 10480 | 55293 |
| Gene name | eukaryotic translation initiation factor 3 subunit M | UEV and lactate/malate dehyrogenase domains | |
| Synonyms | B5|GA17|PCID1|TANGO7|hfl-B5 | ATTP|UEV3 | |
| Cytomap | 11p13 | 11p15.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | eukaryotic translation initiation factor 3 subunit MB5 receptorPCI domain containing 1 (herpesvirus entry mediator)PCI domain-containing protein 1dendritic cell proteinfetal lung protein B5transport and golgi organization 7 homolog | ubiquitin-conjugating enzyme E2 variant 3EV and lactate/malate dehydrogenase domain-containing proteinUEV-3signaling molecule ATTP | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q7L2H7 | Q8IX04 | |
| Ensembl transtripts involved in fusion gene | ENST00000531120, ENST00000524896, ENST00000532054, | ENST00000396197, ENST00000543987, ENST00000540666, ENST00000535484, ENST00000320750, ENST00000379387, ENST00000541984, ENST00000300038, | |
| Fusion gene scores | * DoF score | 6 X 7 X 3=126 | 2 X 2 X 2=8 |
| # samples | 7 | 2 | |
| ** MAII score | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: EIF3M [Title/Abstract] AND UEVLD [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A1KU-01A | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000531120 | ENST00000396197 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| In-frame | ENST00000531120 | ENST00000543987 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000531120 | ENST00000540666 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000531120 | ENST00000535484 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000531120 | ENST00000320750 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000531120 | ENST00000379387 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000531120 | ENST00000541984 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000531120 | ENST00000300038 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| In-frame | ENST00000524896 | ENST00000396197 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| In-frame | ENST00000524896 | ENST00000543987 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000524896 | ENST00000540666 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000524896 | ENST00000535484 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000524896 | ENST00000320750 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000524896 | ENST00000379387 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000524896 | ENST00000541984 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| 5CDS-intron | ENST00000524896 | ENST00000300038 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| intron-3CDS | ENST00000532054 | ENST00000396197 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| intron-3CDS | ENST00000532054 | ENST00000543987 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| intron-intron | ENST00000532054 | ENST00000540666 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| intron-intron | ENST00000532054 | ENST00000535484 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| intron-intron | ENST00000532054 | ENST00000320750 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| intron-intron | ENST00000532054 | ENST00000379387 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| intron-intron | ENST00000532054 | ENST00000541984 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
| intron-intron | ENST00000532054 | ENST00000300038 | EIF3M | chr11 | 32617593 | + | UEVLD | chr11 | 18591924 | - |
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FusionProtFeatures for EIF3M_UEVLD |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| EIF3M | UEVLD |
| Component of the eukaryotic translation initiationfactor 3 (eIF-3) complex, which is required for several steps inthe initiation of protein synthesis (PubMed:17403899,PubMed:25849773, PubMed:27462815). The eIF-3 complex associateswith the 40S ribosome and facilitates the recruitment of eIF-1,eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNArecruitment to the 43S PIC and scanning of the mRNA for AUGrecognition. The eIF-3 complex is also required for disassemblyand recycling of post-termination ribosomal complexes andsubsequently prevents premature joining of the 40S and 60Sribosomal subunits prior to initiation (PubMed:17403899). The eIF-3 complex specifically targets and initiates translation of asubset of mRNAs involved in cell proliferation, including cellcycling, differentiation and apoptosis, and uses different modesof RNA stem-loop binding to exert either translational activationor repression (PubMed:25849773). {ECO:0000255|HAMAP-Rule:MF_03012,ECO:0000269|PubMed:17403899, ECO:0000269|PubMed:25849773,ECO:0000269|PubMed:27462815}. (Microbial infection) May favor virus entry in case ofinfection with herpes simplex virus 1 (HSV1) or herpes simplexvirus 2 (HSV2). {ECO:0000269|PubMed:15919898}. | Possible negative regulator of polyubiquitination.{ECO:0000269|PubMed:12427560}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >UEVLD | chr11:32617593 | chr11:18591924 | ENST00000541984 | - | 0 | 7 | 2_145 | -21 | 200 | Domain | UEV |
| Tgene | >UEVLD | chr11:32617593 | chr11:18591924 | ENST00000300038 | - | 2 | 7 | 191_219 | 64 | 216 | Nucleotide binding | NAD |
| Tgene | >UEVLD | chr11:32617593 | chr11:18591924 | ENST00000320750 | - | 1 | 10 | 191_219 | 42 | 358 | Nucleotide binding | NAD |
| Tgene | >UEVLD | chr11:32617593 | chr11:18591924 | ENST00000379387 | - | 1 | 11 | 191_219 | 42 | 450 | Nucleotide binding | NAD |
| Tgene | >UEVLD | chr11:32617593 | chr11:18591924 | ENST00000396197 | - | 2 | 12 | 191_219 | 64 | 472 | Nucleotide binding | NAD |
| Tgene | >UEVLD | chr11:32617593 | chr11:18591924 | ENST00000535484 | - | 2 | 11 | 191_219 | 26 | 342 | Nucleotide binding | NAD |
| Tgene | >UEVLD | chr11:32617593 | chr11:18591924 | ENST00000541984 | - | 0 | 7 | 191_219 | -21 | 200 | Nucleotide binding | NAD |
| Tgene | >UEVLD | chr11:32617593 | chr11:18591924 | ENST00000543987 | - | 2 | 11 | 191_219 | 64 | 380 | Nucleotide binding | NAD |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >EIF3M | chr11:32617593 | chr11:18591924 | ENST00000531120 | + | 8 | 11 | 180_339 | 266 | 375 | Domain | PCI |
| Tgene | UEVLD | chr11:32617593 | chr11:18591924 | ENST00000300038 | - | 2 | 7 | 2_145 | 64 | 216 | Domain | UEV |
| Tgene | UEVLD | chr11:32617593 | chr11:18591924 | ENST00000320750 | - | 1 | 10 | 2_145 | 42 | 358 | Domain | UEV |
| Tgene | UEVLD | chr11:32617593 | chr11:18591924 | ENST00000379387 | - | 1 | 11 | 2_145 | 42 | 450 | Domain | UEV |
| Tgene | UEVLD | chr11:32617593 | chr11:18591924 | ENST00000396197 | - | 2 | 12 | 2_145 | 64 | 472 | Domain | UEV |
| Tgene | UEVLD | chr11:32617593 | chr11:18591924 | ENST00000535484 | - | 2 | 11 | 2_145 | 26 | 342 | Domain | UEV |
| Tgene | UEVLD | chr11:32617593 | chr11:18591924 | ENST00000543987 | - | 2 | 11 | 2_145 | 64 | 380 | Domain | UEV |
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FusionGeneSequence for EIF3M_UEVLD |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_EIF3M_ENST00000531120_chr11_32617593_+_UEVLD_ENST00000396197_chr11_18591924_-_674aa MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKL VKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDA ASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGNTY NIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHPKSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAY IAKITEGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSASAHSKV VIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQT SGKEVWVIGEQGEDKVLTWSGQEEVVSHTSQVQLSNRAMELLRVKGQRSWSVGLSVADMVDSIVNNKKKVHSVSALAKGYYDINSEVFLS >In-frame_EIF3M_ENST00000531120_chr11_32617593_+_UEVLD_ENST00000543987_chr11_18591924_-_582aa MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKL VKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDA ASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGNTY NIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHPKSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAY IAKITEGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSASAHSKV VIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQT >In-frame_EIF3M_ENST00000524896_chr11_32617593_+_UEVLD_ENST00000396197_chr11_18591924_-_542aa MSVPAFIDISEEDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDH LLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIY LPYLQNWSHPKSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLA ISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLL VASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQEEVVSHTSQVQLSNRAMELL RVKGQRSWSVGLSVADMVDSIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSASSIHSLQQQLK >In-frame_EIF3M_ENST00000524896_chr11_32617593_+_UEVLD_ENST00000543987_chr11_18591924_-_450aa MSVPAFIDISEEDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDH LLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIY LPYLQNWSHPKSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLA ISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLL VASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQEEVVSHTSQVQLSNRDIMIX |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_EIF3M_ENST00000531120_chr11_32617593_+_UEVLD_ENST00000396197_chr11_18591924_-_2022nt ATGAGCGTCCCGGCCTTCATCGACATCAGTGAAGAAGATCAGGCTGCTGAGCTTCGTGCTTATCTGAAATCTAAAGGAGCTGAGATTTCA GAAGAGAACTCGGAAGGTGGACTTCATGTTGATTTAGCTCAAATTATTGAAGCCTGTGATGTGTGTCTGAAGGAGGATGATAAAGATGTT GAAAGTGTGATGAACAGTGTGGTATCCCTACTCTTGATCCTGGAACCAGACAAGCAAGAAGCTTTGATTGAAAGCCTATGTGAAAAGCTG GTCAAATTTCGCGAAGGTGAACGCCCGTCTCTGAGACTGCAGTTGTTAAGCAACCTTTTCCACGGGATGGATAAGAATACTCCTGTAAGA TACACAGTGTATTGCAGCCTTATTAAAGTGGCAGCATCTTGTGGGGCCATCCAGTACATCCCAACTGAGCTGGATCAAGTTAGAAAATGG ATTTCTGACTGGAATCTCACCACTGAAAAAAAGCACACCCTTTTAAGACTACTTTATGAGGCACTTGTGGATTGTAAGAAGAGTGATGCT GCTTCAAAAGTCATGGTGGAATTGCTCGGAAGTTACACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCCCACAGGTGTATTGTACGA GCATTGAAAGATCCAAATGCATTTCTTTTTGACCACCTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGCGAGCTTATTCATGATCTT TTAACCATTTTTGTGAGTGCTAAATTGGCATCATATGTCAAGTTTTATCAGAATAATAAAGACTTCATTGATTCACTTGGTAATACATAT AACATACCAATTCGTTTCTGGATTTTGGATTCTCACCCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACTGCAAATATGGGAATCTTA GTCGGAAAACATGTGGATGCTCAAGGCAGAATATATTTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCTGTCATTGTTGGATTAATT AAAGAAATGATTGCCAAGTTTCAAGAGGAACTTCCCATGTATTCTCTATCATCATCTGATGAGGCACGGCAGGTAGACTTGCTAGCCTAT ATTGCAAAAATCACTGAAGGTGTTTCAGATACAAATTCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTCAATAAAATTACTGTGGTT GGAGGTGGAGAACTCGGTATTGCCTGCACATTAGCAATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTCTTAGACCTCTCAGAAGGG ACTAAAGGAGCCACGATGGACCTTGAAATCTTCAACCTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCCTCTGCTCATTCCAAGGTG GTGATCTTCACAGTCAACTCTTTGGGTAGTTCTCAGTCGTACCTTGATGTGGTACAGAGCAATGTGGATATGTTCAGAGCCCTTGTCCCA GCTCTGGGACATTATAGTCAACACAGTGTCCTGCTCGTTGCATCTCAACCAGTGGAAATCATGACCTATGTAACATGGAAACTGAGTACA TTTCCTGCAAATCGAGTGATCGGAATTGGATGTAATCTGGATTCACAGAGATTACAGTATATTATTACAAATGTTTTGAAGGCACAGACT TCAGGCAAAGAAGTATGGGTTATTGGCGAGCAAGGAGAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAAGTAGTGAGTCATACCTCT CAAGTGCAGCTGTCCAACAGAGCCATGGAACTGCTAAGAGTAAAAGGTCAAAGATCCTGGTCTGTTGGACTATCAGTAGCTGACATGGTT GACAGTATTGTAAACAATAAGAAGAAAGTGCATTCTGTATCAGCTTTAGCAAAGGGATATTATGATATAAATAGTGAAGTGTTTTTAAGT TTGCCTTGCATCCTTGGAACCAATGGAGTATCTGAAGTTATCAAAACCACACTGAAAGAAGATACAGTTACTGAGAAACTCCAAAGCAGT >In-frame_EIF3M_ENST00000531120_chr11_32617593_+_UEVLD_ENST00000543987_chr11_18591924_-_1746nt ATGAGCGTCCCGGCCTTCATCGACATCAGTGAAGAAGATCAGGCTGCTGAGCTTCGTGCTTATCTGAAATCTAAAGGAGCTGAGATTTCA GAAGAGAACTCGGAAGGTGGACTTCATGTTGATTTAGCTCAAATTATTGAAGCCTGTGATGTGTGTCTGAAGGAGGATGATAAAGATGTT GAAAGTGTGATGAACAGTGTGGTATCCCTACTCTTGATCCTGGAACCAGACAAGCAAGAAGCTTTGATTGAAAGCCTATGTGAAAAGCTG GTCAAATTTCGCGAAGGTGAACGCCCGTCTCTGAGACTGCAGTTGTTAAGCAACCTTTTCCACGGGATGGATAAGAATACTCCTGTAAGA TACACAGTGTATTGCAGCCTTATTAAAGTGGCAGCATCTTGTGGGGCCATCCAGTACATCCCAACTGAGCTGGATCAAGTTAGAAAATGG ATTTCTGACTGGAATCTCACCACTGAAAAAAAGCACACCCTTTTAAGACTACTTTATGAGGCACTTGTGGATTGTAAGAAGAGTGATGCT GCTTCAAAAGTCATGGTGGAATTGCTCGGAAGTTACACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCCCACAGGTGTATTGTACGA GCATTGAAAGATCCAAATGCATTTCTTTTTGACCACCTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGCGAGCTTATTCATGATCTT TTAACCATTTTTGTGAGTGCTAAATTGGCATCATATGTCAAGTTTTATCAGAATAATAAAGACTTCATTGATTCACTTGGTAATACATAT AACATACCAATTCGTTTCTGGATTTTGGATTCTCACCCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACTGCAAATATGGGAATCTTA GTCGGAAAACATGTGGATGCTCAAGGCAGAATATATTTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCTGTCATTGTTGGATTAATT AAAGAAATGATTGCCAAGTTTCAAGAGGAACTTCCCATGTATTCTCTATCATCATCTGATGAGGCACGGCAGGTAGACTTGCTAGCCTAT ATTGCAAAAATCACTGAAGGTGTTTCAGATACAAATTCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTCAATAAAATTACTGTGGTT GGAGGTGGAGAACTCGGTATTGCCTGCACATTAGCAATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTCTTAGACCTCTCAGAAGGG ACTAAAGGAGCCACGATGGACCTTGAAATCTTCAACCTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCCTCTGCTCATTCCAAGGTG GTGATCTTCACAGTCAACTCTTTGGGTAGTTCTCAGTCGTACCTTGATGTGGTACAGAGCAATGTGGATATGTTCAGAGCCCTTGTCCCA GCTCTGGGACATTATAGTCAACACAGTGTCCTGCTCGTTGCATCTCAACCAGTGGAAATCATGACCTATGTAACATGGAAACTGAGTACA TTTCCTGCAAATCGAGTGATCGGAATTGGATGTAATCTGGATTCACAGAGATTACAGTATATTATTACAAATGTTTTGAAGGCACAGACT TCAGGCAAAGAAGTATGGGTTATTGGCGAGCAAGGAGAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAAGTAGTGAGTCATACCTCT >In-frame_EIF3M_ENST00000524896_chr11_32617593_+_UEVLD_ENST00000396197_chr11_18591924_-_1626nt ATGAGCGTCCCGGCCTTCATCGACATCAGTGAAGAAGATCAGGTTAGAAAATGGATTTCTGACTGGAATCTCACCACTGAAAAAAAGCAC ACCCTTTTAAGACTACTTTATGAGGCACTTGTGGATTGTAAGAAGAGTGATGCTGCTTCAAAAGTCATGGTGGAATTGCTCGGAAGTTAC ACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCCCACAGGTGTATTGTACGAGCATTGAAAGATCCAAATGCATTTCTTTTTGACCAC CTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGCGAGCTTATTCATGATCTTTTAACCATTTTTGTGAGTGCTAAATTGGCATCATAT GTCAAGTTTTATCAGAATAATAAAGACTTCATTGATTCACTTGGTAATACATATAACATACCAATTCGTTTCTGGATTTTGGATTCTCAC CCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACTGCAAATATGGGAATCTTAGTCGGAAAACATGTGGATGCTCAAGGCAGAATATAT TTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCTGTCATTGTTGGATTAATTAAAGAAATGATTGCCAAGTTTCAAGAGGAACTTCCC ATGTATTCTCTATCATCATCTGATGAGGCACGGCAGGTAGACTTGCTAGCCTATATTGCAAAAATCACTGAAGGTGTTTCAGATACAAAT TCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTCAATAAAATTACTGTGGTTGGAGGTGGAGAACTCGGTATTGCCTGCACATTAGCA ATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTCTTAGACCTCTCAGAAGGGACTAAAGGAGCCACGATGGACCTTGAAATCTTCAAC CTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCCTCTGCTCATTCCAAGGTGGTGATCTTCACAGTCAACTCTTTGGGTAGTTCTCAG TCGTACCTTGATGTGGTACAGAGCAATGTGGATATGTTCAGAGCCCTTGTCCCAGCTCTGGGACATTATAGTCAACACAGTGTCCTGCTC GTTGCATCTCAACCAGTGGAAATCATGACCTATGTAACATGGAAACTGAGTACATTTCCTGCAAATCGAGTGATCGGAATTGGATGTAAT CTGGATTCACAGAGATTACAGTATATTATTACAAATGTTTTGAAGGCACAGACTTCAGGCAAAGAAGTATGGGTTATTGGCGAGCAAGGA GAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAAGTAGTGAGTCATACCTCTCAAGTGCAGCTGTCCAACAGAGCCATGGAACTGCTA AGAGTAAAAGGTCAAAGATCCTGGTCTGTTGGACTATCAGTAGCTGACATGGTTGACAGTATTGTAAACAATAAGAAGAAAGTGCATTCT GTATCAGCTTTAGCAAAGGGATATTATGATATAAATAGTGAAGTGTTTTTAAGTTTGCCTTGCATCCTTGGAACCAATGGAGTATCTGAA GTTATCAAAACCACACTGAAAGAAGATACAGTTACTGAGAAACTCCAAAGCAGTGCATCCTCAATCCACAGTCTCCAACAACAGTTAAAA >In-frame_EIF3M_ENST00000524896_chr11_32617593_+_UEVLD_ENST00000543987_chr11_18591924_-_1350nt ATGAGCGTCCCGGCCTTCATCGACATCAGTGAAGAAGATCAGGTTAGAAAATGGATTTCTGACTGGAATCTCACCACTGAAAAAAAGCAC ACCCTTTTAAGACTACTTTATGAGGCACTTGTGGATTGTAAGAAGAGTGATGCTGCTTCAAAAGTCATGGTGGAATTGCTCGGAAGTTAC ACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCCCACAGGTGTATTGTACGAGCATTGAAAGATCCAAATGCATTTCTTTTTGACCAC CTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGCGAGCTTATTCATGATCTTTTAACCATTTTTGTGAGTGCTAAATTGGCATCATAT GTCAAGTTTTATCAGAATAATAAAGACTTCATTGATTCACTTGGTAATACATATAACATACCAATTCGTTTCTGGATTTTGGATTCTCAC CCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACTGCAAATATGGGAATCTTAGTCGGAAAACATGTGGATGCTCAAGGCAGAATATAT TTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCTGTCATTGTTGGATTAATTAAAGAAATGATTGCCAAGTTTCAAGAGGAACTTCCC ATGTATTCTCTATCATCATCTGATGAGGCACGGCAGGTAGACTTGCTAGCCTATATTGCAAAAATCACTGAAGGTGTTTCAGATACAAAT TCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTCAATAAAATTACTGTGGTTGGAGGTGGAGAACTCGGTATTGCCTGCACATTAGCA ATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTCTTAGACCTCTCAGAAGGGACTAAAGGAGCCACGATGGACCTTGAAATCTTCAAC CTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCCTCTGCTCATTCCAAGGTGGTGATCTTCACAGTCAACTCTTTGGGTAGTTCTCAG TCGTACCTTGATGTGGTACAGAGCAATGTGGATATGTTCAGAGCCCTTGTCCCAGCTCTGGGACATTATAGTCAACACAGTGTCCTGCTC GTTGCATCTCAACCAGTGGAAATCATGACCTATGTAACATGGAAACTGAGTACATTTCCTGCAAATCGAGTGATCGGAATTGGATGTAAT CTGGATTCACAGAGATTACAGTATATTATTACAAATGTTTTGAAGGCACAGACTTCAGGCAAAGAAGTATGGGTTATTGGCGAGCAAGGA GAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAAGTAGTGAGTCATACCTCTCAAGTGCAGCTGTCCAACAGGGATATTATGATATAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_EIF3M_ENST00000531120_chr11_32617593_+_UEVLD_ENST00000396197_chr11_18591924_-_4796nt AGTTCCCTTTTCCGGTCGGCGTGGTCTTGCGAGTGGAGTGTCCGCTGTGCCCGGGCCTGCACCATGAGCGTCCCGGCCTTCATCGACATC AGTGAAGAAGATCAGGCTGCTGAGCTTCGTGCTTATCTGAAATCTAAAGGAGCTGAGATTTCAGAAGAGAACTCGGAAGGTGGACTTCAT GTTGATTTAGCTCAAATTATTGAAGCCTGTGATGTGTGTCTGAAGGAGGATGATAAAGATGTTGAAAGTGTGATGAACAGTGTGGTATCC CTACTCTTGATCCTGGAACCAGACAAGCAAGAAGCTTTGATTGAAAGCCTATGTGAAAAGCTGGTCAAATTTCGCGAAGGTGAACGCCCG TCTCTGAGACTGCAGTTGTTAAGCAACCTTTTCCACGGGATGGATAAGAATACTCCTGTAAGATACACAGTGTATTGCAGCCTTATTAAA GTGGCAGCATCTTGTGGGGCCATCCAGTACATCCCAACTGAGCTGGATCAAGTTAGAAAATGGATTTCTGACTGGAATCTCACCACTGAA AAAAAGCACACCCTTTTAAGACTACTTTATGAGGCACTTGTGGATTGTAAGAAGAGTGATGCTGCTTCAAAAGTCATGGTGGAATTGCTC GGAAGTTACACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCCCACAGGTGTATTGTACGAGCATTGAAAGATCCAAATGCATTTCTT TTTGACCACCTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGCGAGCTTATTCATGATCTTTTAACCATTTTTGTGAGTGCTAAATTG GCATCATATGTCAAGTTTTATCAGAATAATAAAGACTTCATTGATTCACTTGGTAATACATATAACATACCAATTCGTTTCTGGATTTTG GATTCTCACCCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACTGCAAATATGGGAATCTTAGTCGGAAAACATGTGGATGCTCAAGGC AGAATATATTTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCTGTCATTGTTGGATTAATTAAAGAAATGATTGCCAAGTTTCAAGAG GAACTTCCCATGTATTCTCTATCATCATCTGATGAGGCACGGCAGGTAGACTTGCTAGCCTATATTGCAAAAATCACTGAAGGTGTTTCA GATACAAATTCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTCAATAAAATTACTGTGGTTGGAGGTGGAGAACTCGGTATTGCCTGC ACATTAGCAATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTCTTAGACCTCTCAGAAGGGACTAAAGGAGCCACGATGGACCTTGAA ATCTTCAACCTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCCTCTGCTCATTCCAAGGTGGTGATCTTCACAGTCAACTCTTTGGGT AGTTCTCAGTCGTACCTTGATGTGGTACAGAGCAATGTGGATATGTTCAGAGCCCTTGTCCCAGCTCTGGGACATTATAGTCAACACAGT GTCCTGCTCGTTGCATCTCAACCAGTGGAAATCATGACCTATGTAACATGGAAACTGAGTACATTTCCTGCAAATCGAGTGATCGGAATT GGATGTAATCTGGATTCACAGAGATTACAGTATATTATTACAAATGTTTTGAAGGCACAGACTTCAGGCAAAGAAGTATGGGTTATTGGC GAGCAAGGAGAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAAGTAGTGAGTCATACCTCTCAAGTGCAGCTGTCCAACAGAGCCATG GAACTGCTAAGAGTAAAAGGTCAAAGATCCTGGTCTGTTGGACTATCAGTAGCTGACATGGTTGACAGTATTGTAAACAATAAGAAGAAA GTGCATTCTGTATCAGCTTTAGCAAAGGGATATTATGATATAAATAGTGAAGTGTTTTTAAGTTTGCCTTGCATCCTTGGAACCAATGGA GTATCTGAAGTTATCAAAACCACACTGAAAGAAGATACAGTTACTGAGAAACTCCAAAGCAGTGCATCCTCAATCCACAGTCTCCAACAA CAGTTAAAACTTTGATTCTCAAATGCAATTTGAGAGGCTGGACTTCTACCTAAAGGGAAAAGTCATTTAATTTTACCTATATATAGGTTT GAGGATTTCTGTATCCTGCTACTTACTTTTACAAACTGCTTGGTTAAAGTAGAGGGTTTCTTGATTAGCTTTGTGATGTAAATCCTTAAG GAGTTATACAAGGAGGGGAAAAATTAATTTTATTTGGGGTTCTTGAGATATCTATGCTGTTCTTTAAATCTACAGCAGGGGTAAACATTC ATCTGCAGTGTGCATCAATTTAAATCATATATCCTAAACTAAAAGCACAATTCATACTTCGGGAATATTTTATAAGTAATATATCTTTAA AAGAAAATTACCCTTTGACTTTTATAATCAACATAAGTTCCAGGCCCAGTATGGATTTACAAAATCTGTGTCAGTTGTACATTCACAGGA TCCACAGCTTAAGTTACTAATGTTTCTTGTGTAAAATCCTGTTGGTAGTAATAGTAAAGCATTGTATTTCCCTTCTTCAAATTAATTACC TACCAAAAAATGGAAAAGAATTTTACATGCACTTTAAAATAGTAAAATGGAAAGTGAATTTTTAAAATATATGCATTAAAAGTTTACTTT AATTTCCAGTGGGACTTCCTTTATGAAATTTTCCATAACCTCTTCCTGGAGTATTACAAGATCTCCAACATCTCATAAACTAATTGTGAT ATTAGTGGAACCATAAGCAAATATATATTTTTAGTGGAAATAGATTATGAATGAAAGCCAAGCACCTTACTTTAAAGCCAAAATATGAGA TTTTCATTAAAAACATTGGTCATAATAGGGAGAGGTTTTTTATTTGTTCTGAGCAAATCCTTTAACCTCTCCTGATGATACAGTTCAGAG TACACACACTTTGGTGATGGATCAAGAGCAATATTTTCTTATGTGAAAGATAGCTTATTATTACTATTGTGACATACAACTAATAGTAAC AGTTAACATCAACACTTCATATATACCAGGCAGCATGATAAGCACTTTATTATTTTACTGAATCCTCACAACAGACCACTGAGGTAGGGA CTATTGCCATCATCATTTTATAAAAGGAAATTGAGGTTTAGTCCTCAAGAAGTCTTGGCTATTAAGGGGCACTTATCCATACAACCTCTA CTTTTTCTAGGCACTAAAAGGGGGAAAAGGCTTAATAGCCAAAATAGTTATCAAAAGACCCTAAAGCTGGGGTCCTGTACACCATGAAAG GATTACTTTCATTCTCATGTAAGGGCATGCTTTTATAAAAAACAAACATGGGCTAGGCGCAGTGACTCACGCCTGTAATCCCAGCACCTT GGGAGGCTGAGGCGGGCAGATCACGAGGTCAGGAGATTGAGATCATCCTGGCTAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAA AGTTAGCCAGGCGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCGGAAGGCTGAGGCAAGAGAATGGCGTGAACCCGGTAGGTGGAGCTT GCAGTGAGCAGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAGTTTAAAAATTA GCCAGGTGTGGTGATGTGCACCTGTAGTTCCAGCTACTCAGGAGGGTGAGGCAGGAGGATCACTTGAGCCCAGAAGTTCAAGATTGCAAT GAGCTATGATCATGCTACTGCACTCCAGCCTAGGCAACAGAGTGAGACCCTGTCTCTAAAAAAATAAAAATAAAGCAAGCATATAATAGG TTAATCCAGATGGAGTTAGGAGGGTTTATAAGGGCAGACACATCCTAGTAAAGAGGAAATAGGCAAACTAATGCTGTTTTAGTGTAATAA GGAATGCTTATAATGATGAACTTTAGTCATAAAGAAAAGGTGAAATTATATTCAGTAACCCATGTTAGGAAAGCAGAAAACTATTTAATA TGCTTGGAAAGATTCCAACCAGAGTTAACTGAATAAAAACCTTGGACATTTGAAGAGAAAAGCATTTAGTTCTATCTAATTTCAATATGC ACGTGAATTAGTTCATGTTACTCTAACAATGTATTCTTACTGTCCTTTTTTATGAAATAGGAAAGTAAAACTGAAAGAACTATTTCTTGT GTTTTTAAAACTAGCCTTTTCTAATATTTGATATCTAATTAAAGTTAGATAATATGTAATATGCTTTTGAACAATAATCTAACCAGAAAA TATTGTATAATAAATTACCAAGAAATCATTACATTAATTATAAAAGGAACATGTCAATACAACAAATGTTTATTTAACACCTACTGTTAC TCCAAATACTGTGTTAGAATTTGACTATTCGAAGATGAATAATAGTCTTTGCCCTCTGGAAGGCCACAATGTAGAAGTAATTCTCTGTAT CAGATATTTCCTTGAGTGTTAAGTGTATTAGTAATCATGTTGTAAATCCCAGTGTAAGTCAAGAAGCAATATCACCACCACCACCTCCCT ATGATTTTGTGATAATTTGGCATTTTCAATGCTTGTTAACTTTCATGTTTTCATTTTTATGAAATCATGCAGAGCTTGTTATAATTTTTA GTGGGGTTTGGATTAAAATGCTTTTTTGATGTAGCAGAAGATACATTTTTTCCCATTTTACATTGTTTTCCTTAAATATTAAGAATAATG >In-frame_EIF3M_ENST00000531120_chr11_32617593_+_UEVLD_ENST00000543987_chr11_18591924_-_3080nt AGTTCCCTTTTCCGGTCGGCGTGGTCTTGCGAGTGGAGTGTCCGCTGTGCCCGGGCCTGCACCATGAGCGTCCCGGCCTTCATCGACATC AGTGAAGAAGATCAGGCTGCTGAGCTTCGTGCTTATCTGAAATCTAAAGGAGCTGAGATTTCAGAAGAGAACTCGGAAGGTGGACTTCAT GTTGATTTAGCTCAAATTATTGAAGCCTGTGATGTGTGTCTGAAGGAGGATGATAAAGATGTTGAAAGTGTGATGAACAGTGTGGTATCC CTACTCTTGATCCTGGAACCAGACAAGCAAGAAGCTTTGATTGAAAGCCTATGTGAAAAGCTGGTCAAATTTCGCGAAGGTGAACGCCCG TCTCTGAGACTGCAGTTGTTAAGCAACCTTTTCCACGGGATGGATAAGAATACTCCTGTAAGATACACAGTGTATTGCAGCCTTATTAAA GTGGCAGCATCTTGTGGGGCCATCCAGTACATCCCAACTGAGCTGGATCAAGTTAGAAAATGGATTTCTGACTGGAATCTCACCACTGAA AAAAAGCACACCCTTTTAAGACTACTTTATGAGGCACTTGTGGATTGTAAGAAGAGTGATGCTGCTTCAAAAGTCATGGTGGAATTGCTC GGAAGTTACACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCCCACAGGTGTATTGTACGAGCATTGAAAGATCCAAATGCATTTCTT TTTGACCACCTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGCGAGCTTATTCATGATCTTTTAACCATTTTTGTGAGTGCTAAATTG GCATCATATGTCAAGTTTTATCAGAATAATAAAGACTTCATTGATTCACTTGGTAATACATATAACATACCAATTCGTTTCTGGATTTTG GATTCTCACCCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACTGCAAATATGGGAATCTTAGTCGGAAAACATGTGGATGCTCAAGGC AGAATATATTTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCTGTCATTGTTGGATTAATTAAAGAAATGATTGCCAAGTTTCAAGAG GAACTTCCCATGTATTCTCTATCATCATCTGATGAGGCACGGCAGGTAGACTTGCTAGCCTATATTGCAAAAATCACTGAAGGTGTTTCA GATACAAATTCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTCAATAAAATTACTGTGGTTGGAGGTGGAGAACTCGGTATTGCCTGC ACATTAGCAATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTCTTAGACCTCTCAGAAGGGACTAAAGGAGCCACGATGGACCTTGAA ATCTTCAACCTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCCTCTGCTCATTCCAAGGTGGTGATCTTCACAGTCAACTCTTTGGGT AGTTCTCAGTCGTACCTTGATGTGGTACAGAGCAATGTGGATATGTTCAGAGCCCTTGTCCCAGCTCTGGGACATTATAGTCAACACAGT GTCCTGCTCGTTGCATCTCAACCAGTGGAAATCATGACCTATGTAACATGGAAACTGAGTACATTTCCTGCAAATCGAGTGATCGGAATT GGATGTAATCTGGATTCACAGAGATTACAGTATATTATTACAAATGTTTTGAAGGCACAGACTTCAGGCAAAGAAGTATGGGTTATTGGC GAGCAAGGAGAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAAGTAGTGAGTCATACCTCTCAAGTGCAGCTGTCCAACAGGGATATT ATGATATAAATAGTGAAGTGTTTTTAAGTTTGCCTTGCATCCTTGGAACCAATGGAGTATCTGAAGTTATCAAAACCACACTGAAAGAAG ATACAGTTACTGAGAAACTCCAAAGCAGTGCATCCTCAATCCACAGTCTCCAACAACAGTTAAAACTTTGATTCTCAAATGCAATTTGAG AGGCTGGACTTCTACCTAAAGGGAAAAGTCATTTAATTTTACCTATATATAGGTTTGAGGATTTCTGTATCCTGCTACTTACTTTTACAA ACTGCTTGGTTAAAGTAGAGGGTTTCTTGATTAGCTTTGTGATGTAAATCCTTAAGGAGTTATACAAGGAGGGGAAAAATTAATTTTATT TGGGGTTCTTGAGATATCTATGCTGTTCTTTAAATCTACAGCAGGGGTAAACATTCATCTGCAGTGTGCATCAATTTAAATCATATATCC TAAACTAAAAGCACAATTCATACTTCGGGAATATTTTATAAGTAATATATCTTTAAAAGAAAATTACCCTTTGACTTTTATAATCAACAT AAGTTCCAGGCCCAGTATGGATTTACAAAATCTGTGTCAGTTGTACATTCACAGGATCCACAGCTTAAGTTACTAATGTTTCTTGTGTAA AATCCTGTTGGTAGTAATAGTAAAGCATTGTATTTCCCTTCTTCAAATTAATTACCTACCAAAAAATGGAAAAGAATTTTACATGCACTT TAAAATAGTAAAATGGAAAGTGAATTTTTAAAATATATGCATTAAAAGTTTACTTTAATTTCCAGTGGGACTTCCTTTATGAAATTTTCC ATAACCTCTTCCTGGAGTATTACAAGATCTCCAACATCTCATAAACTAATTGTGATATTAGTGGAACCATAAGCAAATATATATTTTTAG TGGAAATAGATTATGAATGAAAGCCAAGCACCTTACTTTAAAGCCAAAATATGAGATTTTCATTAAAAACATTGGTCATAATAGGGAGAG GTTTTTTATTTGTTCTGAGCAAATCCTTTAACCTCTCCTGATGATACAGTTCAGAGTACACACACTTTGGTGATGGATCAAGAGCAATAT TTTCTTATGTGAAAGATAGCTTATTATTACTATTGTGACATACAACTAATAGTAACAGTTAACATCAACACTTCATATATACCAGGCAGC ATGATAAGCACTTTATTATTTTACTGAATCCTCACAACAGACCACTGAGGTAGGGACTATTGCCATCATCATTTTATAAAAGGAAATTGA >In-frame_EIF3M_ENST00000524896_chr11_32617593_+_UEVLD_ENST00000396197_chr11_18591924_-_4391nt TTCCGGTCGGCGTGGTCTTGCGAGTGGAGTGTCCGCTGTGCCCGGGCCTGCACCATGAGCGTCCCGGCCTTCATCGACATCAGTGAAGAA GATCAGGTTAGAAAATGGATTTCTGACTGGAATCTCACCACTGAAAAAAAGCACACCCTTTTAAGACTACTTTATGAGGCACTTGTGGAT TGTAAGAAGAGTGATGCTGCTTCAAAAGTCATGGTGGAATTGCTCGGAAGTTACACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCC CACAGGTGTATTGTACGAGCATTGAAAGATCCAAATGCATTTCTTTTTGACCACCTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGC GAGCTTATTCATGATCTTTTAACCATTTTTGTGAGTGCTAAATTGGCATCATATGTCAAGTTTTATCAGAATAATAAAGACTTCATTGAT TCACTTGGTAATACATATAACATACCAATTCGTTTCTGGATTTTGGATTCTCACCCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACT GCAAATATGGGAATCTTAGTCGGAAAACATGTGGATGCTCAAGGCAGAATATATTTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCT GTCATTGTTGGATTAATTAAAGAAATGATTGCCAAGTTTCAAGAGGAACTTCCCATGTATTCTCTATCATCATCTGATGAGGCACGGCAG GTAGACTTGCTAGCCTATATTGCAAAAATCACTGAAGGTGTTTCAGATACAAATTCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTC AATAAAATTACTGTGGTTGGAGGTGGAGAACTCGGTATTGCCTGCACATTAGCAATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTC TTAGACCTCTCAGAAGGGACTAAAGGAGCCACGATGGACCTTGAAATCTTCAACCTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCC TCTGCTCATTCCAAGGTGGTGATCTTCACAGTCAACTCTTTGGGTAGTTCTCAGTCGTACCTTGATGTGGTACAGAGCAATGTGGATATG TTCAGAGCCCTTGTCCCAGCTCTGGGACATTATAGTCAACACAGTGTCCTGCTCGTTGCATCTCAACCAGTGGAAATCATGACCTATGTA ACATGGAAACTGAGTACATTTCCTGCAAATCGAGTGATCGGAATTGGATGTAATCTGGATTCACAGAGATTACAGTATATTATTACAAAT GTTTTGAAGGCACAGACTTCAGGCAAAGAAGTATGGGTTATTGGCGAGCAAGGAGAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAA GTAGTGAGTCATACCTCTCAAGTGCAGCTGTCCAACAGAGCCATGGAACTGCTAAGAGTAAAAGGTCAAAGATCCTGGTCTGTTGGACTA TCAGTAGCTGACATGGTTGACAGTATTGTAAACAATAAGAAGAAAGTGCATTCTGTATCAGCTTTAGCAAAGGGATATTATGATATAAAT AGTGAAGTGTTTTTAAGTTTGCCTTGCATCCTTGGAACCAATGGAGTATCTGAAGTTATCAAAACCACACTGAAAGAAGATACAGTTACT GAGAAACTCCAAAGCAGTGCATCCTCAATCCACAGTCTCCAACAACAGTTAAAACTTTGATTCTCAAATGCAATTTGAGAGGCTGGACTT CTACCTAAAGGGAAAAGTCATTTAATTTTACCTATATATAGGTTTGAGGATTTCTGTATCCTGCTACTTACTTTTACAAACTGCTTGGTT AAAGTAGAGGGTTTCTTGATTAGCTTTGTGATGTAAATCCTTAAGGAGTTATACAAGGAGGGGAAAAATTAATTTTATTTGGGGTTCTTG AGATATCTATGCTGTTCTTTAAATCTACAGCAGGGGTAAACATTCATCTGCAGTGTGCATCAATTTAAATCATATATCCTAAACTAAAAG CACAATTCATACTTCGGGAATATTTTATAAGTAATATATCTTTAAAAGAAAATTACCCTTTGACTTTTATAATCAACATAAGTTCCAGGC CCAGTATGGATTTACAAAATCTGTGTCAGTTGTACATTCACAGGATCCACAGCTTAAGTTACTAATGTTTCTTGTGTAAAATCCTGTTGG TAGTAATAGTAAAGCATTGTATTTCCCTTCTTCAAATTAATTACCTACCAAAAAATGGAAAAGAATTTTACATGCACTTTAAAATAGTAA AATGGAAAGTGAATTTTTAAAATATATGCATTAAAAGTTTACTTTAATTTCCAGTGGGACTTCCTTTATGAAATTTTCCATAACCTCTTC CTGGAGTATTACAAGATCTCCAACATCTCATAAACTAATTGTGATATTAGTGGAACCATAAGCAAATATATATTTTTAGTGGAAATAGAT TATGAATGAAAGCCAAGCACCTTACTTTAAAGCCAAAATATGAGATTTTCATTAAAAACATTGGTCATAATAGGGAGAGGTTTTTTATTT GTTCTGAGCAAATCCTTTAACCTCTCCTGATGATACAGTTCAGAGTACACACACTTTGGTGATGGATCAAGAGCAATATTTTCTTATGTG AAAGATAGCTTATTATTACTATTGTGACATACAACTAATAGTAACAGTTAACATCAACACTTCATATATACCAGGCAGCATGATAAGCAC TTTATTATTTTACTGAATCCTCACAACAGACCACTGAGGTAGGGACTATTGCCATCATCATTTTATAAAAGGAAATTGAGGTTTAGTCCT CAAGAAGTCTTGGCTATTAAGGGGCACTTATCCATACAACCTCTACTTTTTCTAGGCACTAAAAGGGGGAAAAGGCTTAATAGCCAAAAT AGTTATCAAAAGACCCTAAAGCTGGGGTCCTGTACACCATGAAAGGATTACTTTCATTCTCATGTAAGGGCATGCTTTTATAAAAAACAA ACATGGGCTAGGCGCAGTGACTCACGCCTGTAATCCCAGCACCTTGGGAGGCTGAGGCGGGCAGATCACGAGGTCAGGAGATTGAGATCA TCCTGGCTAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAGTTAGCCAGGCGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCG GAAGGCTGAGGCAAGAGAATGGCGTGAACCCGGTAGGTGGAGCTTGCAGTGAGCAGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAG AGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAGTTTAAAAATTAGCCAGGTGTGGTGATGTGCACCTGTAGTTCCAGCTACTCAGGAGG GTGAGGCAGGAGGATCACTTGAGCCCAGAAGTTCAAGATTGCAATGAGCTATGATCATGCTACTGCACTCCAGCCTAGGCAACAGAGTGA GACCCTGTCTCTAAAAAAATAAAAATAAAGCAAGCATATAATAGGTTAATCCAGATGGAGTTAGGAGGGTTTATAAGGGCAGACACATCC TAGTAAAGAGGAAATAGGCAAACTAATGCTGTTTTAGTGTAATAAGGAATGCTTATAATGATGAACTTTAGTCATAAAGAAAAGGTGAAA TTATATTCAGTAACCCATGTTAGGAAAGCAGAAAACTATTTAATATGCTTGGAAAGATTCCAACCAGAGTTAACTGAATAAAAACCTTGG ACATTTGAAGAGAAAAGCATTTAGTTCTATCTAATTTCAATATGCACGTGAATTAGTTCATGTTACTCTAACAATGTATTCTTACTGTCC TTTTTTATGAAATAGGAAAGTAAAACTGAAAGAACTATTTCTTGTGTTTTTAAAACTAGCCTTTTCTAATATTTGATATCTAATTAAAGT TAGATAATATGTAATATGCTTTTGAACAATAATCTAACCAGAAAATATTGTATAATAAATTACCAAGAAATCATTACATTAATTATAAAA GGAACATGTCAATACAACAAATGTTTATTTAACACCTACTGTTACTCCAAATACTGTGTTAGAATTTGACTATTCGAAGATGAATAATAG TCTTTGCCCTCTGGAAGGCCACAATGTAGAAGTAATTCTCTGTATCAGATATTTCCTTGAGTGTTAAGTGTATTAGTAATCATGTTGTAA ATCCCAGTGTAAGTCAAGAAGCAATATCACCACCACCACCTCCCTATGATTTTGTGATAATTTGGCATTTTCAATGCTTGTTAACTTTCA TGTTTTCATTTTTATGAAATCATGCAGAGCTTGTTATAATTTTTAGTGGGGTTTGGATTAAAATGCTTTTTTGATGTAGCAGAAGATACA >In-frame_EIF3M_ENST00000524896_chr11_32617593_+_UEVLD_ENST00000543987_chr11_18591924_-_2675nt TTCCGGTCGGCGTGGTCTTGCGAGTGGAGTGTCCGCTGTGCCCGGGCCTGCACCATGAGCGTCCCGGCCTTCATCGACATCAGTGAAGAA GATCAGGTTAGAAAATGGATTTCTGACTGGAATCTCACCACTGAAAAAAAGCACACCCTTTTAAGACTACTTTATGAGGCACTTGTGGAT TGTAAGAAGAGTGATGCTGCTTCAAAAGTCATGGTGGAATTGCTCGGAAGTTACACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCC CACAGGTGTATTGTACGAGCATTGAAAGATCCAAATGCATTTCTTTTTGACCACCTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGC GAGCTTATTCATGATCTTTTAACCATTTTTGTGAGTGCTAAATTGGCATCATATGTCAAGTTTTATCAGAATAATAAAGACTTCATTGAT TCACTTGGTAATACATATAACATACCAATTCGTTTCTGGATTTTGGATTCTCACCCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACT GCAAATATGGGAATCTTAGTCGGAAAACATGTGGATGCTCAAGGCAGAATATATTTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCT GTCATTGTTGGATTAATTAAAGAAATGATTGCCAAGTTTCAAGAGGAACTTCCCATGTATTCTCTATCATCATCTGATGAGGCACGGCAG GTAGACTTGCTAGCCTATATTGCAAAAATCACTGAAGGTGTTTCAGATACAAATTCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTC AATAAAATTACTGTGGTTGGAGGTGGAGAACTCGGTATTGCCTGCACATTAGCAATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTC TTAGACCTCTCAGAAGGGACTAAAGGAGCCACGATGGACCTTGAAATCTTCAACCTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCC TCTGCTCATTCCAAGGTGGTGATCTTCACAGTCAACTCTTTGGGTAGTTCTCAGTCGTACCTTGATGTGGTACAGAGCAATGTGGATATG TTCAGAGCCCTTGTCCCAGCTCTGGGACATTATAGTCAACACAGTGTCCTGCTCGTTGCATCTCAACCAGTGGAAATCATGACCTATGTA ACATGGAAACTGAGTACATTTCCTGCAAATCGAGTGATCGGAATTGGATGTAATCTGGATTCACAGAGATTACAGTATATTATTACAAAT GTTTTGAAGGCACAGACTTCAGGCAAAGAAGTATGGGTTATTGGCGAGCAAGGAGAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAA GTAGTGAGTCATACCTCTCAAGTGCAGCTGTCCAACAGGGATATTATGATATAAATAGTGAAGTGTTTTTAAGTTTGCCTTGCATCCTTG GAACCAATGGAGTATCTGAAGTTATCAAAACCACACTGAAAGAAGATACAGTTACTGAGAAACTCCAAAGCAGTGCATCCTCAATCCACA GTCTCCAACAACAGTTAAAACTTTGATTCTCAAATGCAATTTGAGAGGCTGGACTTCTACCTAAAGGGAAAAGTCATTTAATTTTACCTA TATATAGGTTTGAGGATTTCTGTATCCTGCTACTTACTTTTACAAACTGCTTGGTTAAAGTAGAGGGTTTCTTGATTAGCTTTGTGATGT AAATCCTTAAGGAGTTATACAAGGAGGGGAAAAATTAATTTTATTTGGGGTTCTTGAGATATCTATGCTGTTCTTTAAATCTACAGCAGG GGTAAACATTCATCTGCAGTGTGCATCAATTTAAATCATATATCCTAAACTAAAAGCACAATTCATACTTCGGGAATATTTTATAAGTAA TATATCTTTAAAAGAAAATTACCCTTTGACTTTTATAATCAACATAAGTTCCAGGCCCAGTATGGATTTACAAAATCTGTGTCAGTTGTA CATTCACAGGATCCACAGCTTAAGTTACTAATGTTTCTTGTGTAAAATCCTGTTGGTAGTAATAGTAAAGCATTGTATTTCCCTTCTTCA AATTAATTACCTACCAAAAAATGGAAAAGAATTTTACATGCACTTTAAAATAGTAAAATGGAAAGTGAATTTTTAAAATATATGCATTAA AAGTTTACTTTAATTTCCAGTGGGACTTCCTTTATGAAATTTTCCATAACCTCTTCCTGGAGTATTACAAGATCTCCAACATCTCATAAA CTAATTGTGATATTAGTGGAACCATAAGCAAATATATATTTTTAGTGGAAATAGATTATGAATGAAAGCCAAGCACCTTACTTTAAAGCC AAAATATGAGATTTTCATTAAAAACATTGGTCATAATAGGGAGAGGTTTTTTATTTGTTCTGAGCAAATCCTTTAACCTCTCCTGATGAT ACAGTTCAGAGTACACACACTTTGGTGATGGATCAAGAGCAATATTTTCTTATGTGAAAGATAGCTTATTATTACTATTGTGACATACAA CTAATAGTAACAGTTAACATCAACACTTCATATATACCAGGCAGCATGATAAGCACTTTATTATTTTACTGAATCCTCACAACAGACCAC |
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FusionGenePPI for EIF3M_UEVLD |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| EIF3M | EIF1B, EIF4A2, EIF3A, EIF3F, EIF3H, TADA2A, EIF3B, APP, EIF3C, EIF3E, EIF3D, EIF3I, EIF3K, EIF3L, EIF3G, MMS19, NPM1, EXOSC10, SRPK1, FAM96B, HUWE1, EGFR, EIF3CL, USP34, HSPB1, AHCYL1, COPS4, RPN1, EIF3J, NTRK1, MED4, HERC2, NF2, PTP4A1, PSMD12, EIF4A1, GPBP1L1, UBE2N, CYLD, DLD, TRIM25, G3BP1, BRCA1 | UEVLD | RNF4, RNF114, TRAF6, DTX3, LRSAM1, UBC, WDR59 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | EIF3M | chr11:32617593 | chr11:18591924 | ENST00000531120 | + | 8 | 11 | 344_374 | 266 | 375 | HSV-1 and HSV-2 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for EIF3M_UEVLD |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for EIF3M_UEVLD |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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