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Fusion gene ID: 11140 |
FusionGeneSummary for EHBP1_BCL11A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: EHBP1_BCL11A | Fusion gene ID: 11140 | Hgene | Tgene | Gene symbol | EHBP1 | BCL11A | Gene ID | 23301 | 53335 |
| Gene name | EH domain binding protein 1 | B cell CLL/lymphoma 11A | |
| Synonyms | HPC12|NACSIN | BCL11A-L|BCL11A-S|BCL11A-XL|BCL11a-M|CTIP1|DILOS|EVI9|HBFQTL5|ZNF856 | |
| Cytomap | 2p15 | 2p16.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | EH domain-binding protein 1NPF calponin-like proteintestis tissue sperm-binding protein Li 50e | B-cell lymphoma/leukemia 11AB-cell CLL/lymphoma 11A (zinc finger protein) isoform 2BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1C2H2-type zinc finger proteinCOUP-TF-interacting protein 1ecotropic viral integration site 9 homologecot | |
| Modification date | 20180519 | 20180527 | |
| UniProtAcc | Q8NDI1 | Q9H165 | |
| Ensembl transtripts involved in fusion gene | ENST00000405015, ENST00000431489, ENST00000354487, ENST00000263991, ENST00000405289, ENST00000496857, | ENST00000356842, ENST00000359629, ENST00000538214, ENST00000537768, ENST00000335712, ENST00000477659, ENST00000358510, | |
| Fusion gene scores | * DoF score | 6 X 9 X 8=432 | 9 X 8 X 3=216 |
| # samples | 12 | 8 | |
| ** MAII score | log2(12/432*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/216*10)=-1.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: EHBP1 [Title/Abstract] AND BCL11A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | BCL11A | GO:0000122 | negative regulation of transcription by RNA polymerase II | 19153051 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-D8-A147-01A | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000405015 | ENST00000356842 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000405015 | ENST00000359629 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000405015 | ENST00000538214 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| In-frame | ENST00000405015 | ENST00000537768 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000405015 | ENST00000335712 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000405015 | ENST00000477659 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000405015 | ENST00000358510 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000431489 | ENST00000356842 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000431489 | ENST00000359629 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000431489 | ENST00000538214 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| In-frame | ENST00000431489 | ENST00000537768 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000431489 | ENST00000335712 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000431489 | ENST00000477659 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000431489 | ENST00000358510 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000354487 | ENST00000356842 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000354487 | ENST00000359629 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000354487 | ENST00000538214 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| In-frame | ENST00000354487 | ENST00000537768 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000354487 | ENST00000335712 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000354487 | ENST00000477659 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000354487 | ENST00000358510 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000263991 | ENST00000356842 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000263991 | ENST00000359629 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000263991 | ENST00000538214 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| In-frame | ENST00000263991 | ENST00000537768 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000263991 | ENST00000335712 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000263991 | ENST00000477659 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000263991 | ENST00000358510 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000405289 | ENST00000356842 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000405289 | ENST00000359629 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| Frame-shift | ENST00000405289 | ENST00000538214 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| In-frame | ENST00000405289 | ENST00000537768 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000405289 | ENST00000335712 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000405289 | ENST00000477659 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| 5CDS-intron | ENST00000405289 | ENST00000358510 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| intron-3CDS | ENST00000496857 | ENST00000356842 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| intron-3CDS | ENST00000496857 | ENST00000359629 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| intron-3CDS | ENST00000496857 | ENST00000538214 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| intron-3CDS | ENST00000496857 | ENST00000537768 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| intron-intron | ENST00000496857 | ENST00000335712 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| intron-intron | ENST00000496857 | ENST00000477659 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
| intron-intron | ENST00000496857 | ENST00000358510 | EHBP1 | chr2 | 63101667 | + | BCL11A | chr2 | 60679801 | - |
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FusionProtFeatures for EHBP1_BCL11A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| EHBP1 | BCL11A |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for EHBP1_BCL11A |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_EHBP1_ENST00000405015_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_425aa MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKDPHA EEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQ ADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYN NSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETER >In-frame_EHBP1_ENST00000431489_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_425aa MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKDPHA EEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQ ADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYN NSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETER >In-frame_EHBP1_ENST00000354487_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_425aa MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKDPHA EEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQ ADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYN NSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETER >In-frame_EHBP1_ENST00000263991_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_460aa MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKDPHA EEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQ ADIGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPF DDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSK TEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKVLHTPPFGVVPRELKMCGSF >In-frame_EHBP1_ENST00000405289_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_425aa MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKDPHA EEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQ ADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYN NSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETER |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_EHBP1_ENST00000405015_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_1277nt ATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAG TGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCT GGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCG GAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT ACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCT GCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAAT AACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCT CCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAA TTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGG CGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTC TCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGA >In-frame_EHBP1_ENST00000431489_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_1277nt ATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAG TGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCT GGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCG GAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT ACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCT GCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAAT AACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCT CCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAA TTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGG CGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTC TCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGA >In-frame_EHBP1_ENST00000354487_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_1277nt ATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAG TGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCT GGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCG GAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT ACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCT GCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAAT AACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCT CCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAA TTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGG CGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTC TCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGA >In-frame_EHBP1_ENST00000263991_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_1382nt ATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAG TGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCT GGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCG GAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT ACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACTGCATAAAGCAAGCAAATATGCGTTCAGCTAAA TCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTT GATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAA GACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTG ACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAA ACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAA CTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCT GCAGGAAAAGATCTCTCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTT >In-frame_EHBP1_ENST00000405289_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_1277nt ATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAG TGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCT GGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCG GAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT ACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCT GCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAAT AACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCT CCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAA TTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGG CGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTC TCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_EHBP1_ENST00000405015_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_1880nt AACTGGGAGGCTCCCCAGTTTGTGGGTAACATCTGACTCTCCCTCCCCAAAGAGAGACTCCAGCGAGAGACTGGGGATTTGGAGGTCCAA GTCATGGCAGAACTGGGTTGCTTGCTAGGACACAAGGTTAGCATGCCCCTGTAGCAGCAATGTGAGAATCAGAAAAGGTGACTGTGCATC TCAAGAAGCCGAATCAAAAAGCCAAGCCAACCACCTAACCAGTGATTTTCAAGCCCTCCAGAATACCCATCATATAGCCCCTGAGGTGGC ATGGTGATGTCTCCATGAGGGAACCCCTTCCCACTCATCCTGTCACGTATATCATAGTGTTCTTGACTGGGCCATTCATCTAAGATGGGA TTTACCCTGTGAAACAGGGAGAAGACTTATGGACCCCAAGCATCATTTCGAGTTGTAGTTGAGTTTTTAAAAGACATACATGCAAAGTTC CTTTGCTTTGGACCCTCTGCATTATTAAAGCTGCTGTATTGCTAACCCAGAACTGCTCCAGTGTCTTGACTGATCATCATGGCTTCAGTT TGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAGTGTACGAAGAAA TGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCTGGAATAAAAAAT CCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCGGAAGAATTTGAA GACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTAT GCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTA TCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGC AATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATC AACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAAT CCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAAT CCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCT ACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCA AATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGA AAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCT AAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGAGAGCCCTTAAGT >In-frame_EHBP1_ENST00000431489_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_1958nt GATGATGGTGGCGGAGGAGAAAGGCGGGGGAGGGGGTGCTGGGCGCTGAGCGGTGGCTCTGGCAGGGCTTGGTAGGGTGGGGGACGGTCG CGGGGCGATCTGTCAGGGAGGGGGTGGGCGTGAGGGGCGCCGTCCGCCTGAGGGGCTGCAGATCCCGGCTACCGCGAGCGCCGTGGCTGG CTTGGCTGTTCCATGTGGCTCCGGCGGGGATGGAGGACTCGGTGGCGGCGGCGGCTGCTGCTGCGGCGGCGACGGAGGAGCGGCTATGAG AAGGGAACGGGGCCAGACTCAGCCCGACAGCGGGATTAGAGCCCTCCAGAATACCCATCATATAGCCCCTGAGGTGGCATGGTGATGTCT CCATGAGGGAACCCCTTCCCACTCATCCTGTCACGTATATCATAGTGTTCTTGACTGGGCCATTCATCTAAGATGGGATTTACCCTGTGA AACAGGGAGAAGACTTATGGACCCCAAGCATCATTTCGAGTTGTAGTTGAGTTTTTAAAAGACATACATGCAAAGTTCCTTTGCTTTGGA CCCTCTGCATTATTAAAGCTGCTGTATTGCTAACCCAGAACTGCTCCAGTGTCTTGACTGATCATCATGGCTTCAGTTTGGAAGAGACTG CAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAGTGTACGAAGAAATGGCAACCAGAT AAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCTGGAATAAAAAATCCCTATCGTGGT GTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCGGAAGAATTTGAAGACAAAGAGTGG ACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATG CCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTT CTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGAC TTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAAC TTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGAT CCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAG GTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAA AATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTAT GAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCT CCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGGTTCTTCAC ACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGAGAGCCCTTAAGTTCTGAGAAAATT >In-frame_EHBP1_ENST00000354487_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_1834nt GGGCGCCGTCCGCCTGAGGGGCTGCAGATCCCGGCTACCGCGAGCGCCGTGGCTGGCTTGGCTGTTCCATGTGGCTCCGGCGGGGATGGA GGACTCGGTGGCGGCGGCGGCTGCTGCTGCGGCGGCGACGGAGGAGCGGCTATGAGAAGGGAACGGGGCCAGACTCAGCCCGACAGCGGG ATTAGAGCCCTCCAGAATACCCATCATATAGCCCCTGAGGTGGCATGGTGATGTCTCCATGAGGGAACCCCTTCCCACTCATCCTGTCAC GTATATCATAGTGTTCTTGACTGGGCCATTCATCTAAGATGGGATTTACCCTGTGAAACAGGGAGAAGACTTATGGACCCCAAGCATCAT TTCGAGTTGTAGTTGAGTTTTTAAAAGACATACATGCAAAGTTCCTTTGCTTTGGACCCTCTGCATTATTAAAGCTGCTGTATTGCTAAC CCAGAACTGCTCCAGTGTCTTGACTGATCATCATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGT TTGTGGCCTCCTACCAGGAGCTCATGGTTGAGTGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAA GGAAGTCTTCTAAGGCACATAGCTGGCAACCTGGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAA TCACTGTAACACTTTTTAAGGATCCTCATGCGGAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTC GAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGC CATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGC AAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACA GAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCG TGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTT CACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATG AGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCT ATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGG TAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAA ATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCA AGATGTGTGGCAGTTTTCGGATGGAAGCTCGAGAGCCCTTAAGTTCTGAGAAAATTTGAAGCCCCCAGGGGTGGGGTGGACGCGTGCCGC >In-frame_EHBP1_ENST00000263991_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_1939nt GGGCGCCGTCCGCCTGAGGGGCTGCAGATCCCGGCTACCGCGAGCGCCGTGGCTGGCTTGGCTGTTCCATGTGGCTCCGGCGGGGATGGA GGACTCGGTGGCGGCGGCGGCTGCTGCTGCGGCGGCGACGGAGGAGCGGCTATGAGAAGGGAACGGGGCCAGACTCAGCCCGACAGCGGG ATTAGAGCCCTCCAGAATACCCATCATATAGCCCCTGAGGTGGCATGGTGATGTCTCCATGAGGGAACCCCTTCCCACTCATCCTGTCAC GTATATCATAGTGTTCTTGACTGGGCCATTCATCTAAGATGGGATTTACCCTGTGAAACAGGGAGAAGACTTATGGACCCCAAGCATCAT TTCGAGTTGTAGTTGAGTTTTTAAAAGACATACATGCAAAGTTCCTTTGCTTTGGACCCTCTGCATTATTAAAGCTGCTGTATTGCTAAC CCAGAACTGCTCCAGTGTCTTGACTGATCATCATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGT TTGTGGCCTCCTACCAGGAGCTCATGGTTGAGTGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAA GGAAGTCTTCTAAGGCACATAGCTGGCAACCTGGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAA TCACTGTAACACTTTTTAAGGATCCTCATGCGGAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTC GAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGC CATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGC AAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACA GAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACT GCATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAA AGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTA TCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATT TGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATA TGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTC CTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAA AAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAG TACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGAGAGCCCTTAAGTTCTGAGAAAATTTGAAGCCCCCAGGGGTGGG >In-frame_EHBP1_ENST00000405289_chr2_63101667_+_BCL11A_ENST00000537768_chr2_60679801_-_1352nt ATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAG TGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCT GGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCG GAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT ACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCT GCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAAT AACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCT CCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAA TTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGG CGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTC TCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGA GAGCCCTTAAGTTCTGAGAAAATTTGAAGCCCCCAGGGGTGGGGTGGACGCGTGCCGCCCAGTCGACGTCAGCGTGGTCTGTCATCCTGC |
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FusionGenePPI for EHBP1_BCL11A |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| EHBP1 | EHD2, KHDRBS2, RPAP2, PACSIN1, COPS5, COPS6, IFT57, OFD1, TMEM17, XPO1, CDH1, SOAT1, NDUFS1, ACAP2, TRIM25 | BCL11A | NR2F1, CHD4, MTA2, MTA1, HDAC1, MBD3, SIRT1, BCL6, BCL11A, APP, CDK4, CDK6, HDAC2, YME1L1, CDCA3, ACTC1, NR2F2, NR2E1, NR2E3, NR2F6, LMO1, NCK2, ZBTB24, GMCL1P1, UBE2I, PIAS3, PHF20L1, RBBP7, UBXN4, MBD3L1, FGFR2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for EHBP1_BCL11A |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for EHBP1_BCL11A |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | EHBP1 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Tgene | BCL11A | C0003635 | Apraxias | 1 | CTD_human |
| Tgene | BCL11A | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human |
| Tgene | BCL11A | C0023014 | Language Development Disorders | 1 | CTD_human |
| Tgene | BCL11A | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human |
| Tgene | BCL11A | C0036095 | Salivary Gland Neoplasms | 1 | CTD_human |
| Tgene | BCL11A | C0036341 | Schizophrenia | 1 | PSYGENET |
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