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Fusion gene ID: 11106 |
FusionGeneSummary for EGFR_ERP44 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: EGFR_ERP44 | Fusion gene ID: 11106 | Hgene | Tgene | Gene symbol | EGFR | ERP44 | Gene ID | 1956 | 23071 |
| Gene name | epidermal growth factor receptor | endoplasmic reticulum protein 44 | |
| Synonyms | ERBB|ERBB1|HER1|NISBD2|PIG61|mENA | PDIA10|TXNDC4 | |
| Cytomap | 7p11.2 | 9q31.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | epidermal growth factor receptoravian erythroblastic leukemia viral (v-erb-b) oncogene homologcell growth inhibiting protein 40cell proliferation-inducing protein 61epidermal growth factor receptor tyrosine kinase domainerb-b2 receptor tyrosine kinas | endoplasmic reticulum resident protein 44ER protein 44endoplasmic reticulum resident protein 44 kDaprotein disulfide isomerase family A, member 10thioredoxin domain containing 4 (endoplasmic reticulum)thioredoxin domain-containing protein 4 | |
| Modification date | 20180527 | 20180522 | |
| UniProtAcc | P00533 | Q9BS26 | |
| Ensembl transtripts involved in fusion gene | ENST00000455089, ENST00000342916, ENST00000344576, ENST00000420316, ENST00000275493, ENST00000442591, ENST00000463948, ENST00000454757, | ENST00000262455, | |
| Fusion gene scores | * DoF score | 18 X 8 X 8=1152 | 3 X 3 X 2=18 |
| # samples | 17 | 2 | |
| ** MAII score | log2(17/1152*10)=-2.76053406530461 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/18*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: EGFR [Title/Abstract] AND ERP44 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | EGFR | GO:0001934 | positive regulation of protein phosphorylation | 20551055 |
| Hgene | EGFR | GO:0007165 | signal transduction | 10572067 |
| Hgene | EGFR | GO:0007166 | cell surface receptor signaling pathway | 7736574 |
| Hgene | EGFR | GO:0007173 | epidermal growth factor receptor signaling pathway | 7736574|12435727 |
| Hgene | EGFR | GO:0008283 | cell proliferation | 17115032 |
| Hgene | EGFR | GO:0008284 | positive regulation of cell proliferation | 7736574 |
| Hgene | EGFR | GO:0010750 | positive regulation of nitric oxide mediated signal transduction | 12828935 |
| Hgene | EGFR | GO:0018108 | peptidyl-tyrosine phosphorylation | 22732145 |
| Hgene | EGFR | GO:0030307 | positive regulation of cell growth | 15467833 |
| Hgene | EGFR | GO:0031659 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | 18483258 |
| Hgene | EGFR | GO:0042177 | negative regulation of protein catabolic process | 17115032 |
| Hgene | EGFR | GO:0042327 | positive regulation of phosphorylation | 15082764 |
| Hgene | EGFR | GO:0043406 | positive regulation of MAP kinase activity | 10572067 |
| Hgene | EGFR | GO:0045739 | positive regulation of DNA repair | 17115032 |
| Hgene | EGFR | GO:0045740 | positive regulation of DNA replication | 17115032 |
| Hgene | EGFR | GO:0045944 | positive regulation of transcription by RNA polymerase II | 20551055 |
| Hgene | EGFR | GO:0050679 | positive regulation of epithelial cell proliferation | 10572067 |
| Hgene | EGFR | GO:0050999 | regulation of nitric-oxide synthase activity | 12828935 |
| Hgene | EGFR | GO:0070141 | response to UV-A | 18483258 |
| Hgene | EGFR | GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 20551055 |
| Hgene | EGFR | GO:0071392 | cellular response to estradiol stimulus | 20551055 |
| Hgene | EGFR | GO:1900020 | positive regulation of protein kinase C activity | 22732145 |
| Hgene | EGFR | GO:1903078 | positive regulation of protein localization to plasma membrane | 22732145 |
| Tgene | ERP44 | GO:0006457 | protein folding | 11847130 |
| Tgene | ERP44 | GO:0006986 | response to unfolded protein | 11847130 |
| Tgene | ERP44 | GO:0009100 | glycoprotein metabolic process | 11847130 |
| Tgene | ERP44 | GO:0034976 | response to endoplasmic reticulum stress | 11847130 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | GBM | TCGA-06-0744-01A | EGFR | chr7 | 55087058 | + | ERP44 | chr9 | 102784508 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000455089 | ENST00000262455 | EGFR | chr7 | 55087058 | + | ERP44 | chr9 | 102784508 | - |
| In-frame | ENST00000342916 | ENST00000262455 | EGFR | chr7 | 55087058 | + | ERP44 | chr9 | 102784508 | - |
| In-frame | ENST00000344576 | ENST00000262455 | EGFR | chr7 | 55087058 | + | ERP44 | chr9 | 102784508 | - |
| In-frame | ENST00000420316 | ENST00000262455 | EGFR | chr7 | 55087058 | + | ERP44 | chr9 | 102784508 | - |
| In-frame | ENST00000275493 | ENST00000262455 | EGFR | chr7 | 55087058 | + | ERP44 | chr9 | 102784508 | - |
| In-frame | ENST00000442591 | ENST00000262455 | EGFR | chr7 | 55087058 | + | ERP44 | chr9 | 102784508 | - |
| 3UTR-3CDS | ENST00000463948 | ENST00000262455 | EGFR | chr7 | 55087058 | + | ERP44 | chr9 | 102784508 | - |
| intron-3CDS | ENST00000454757 | ENST00000262455 | EGFR | chr7 | 55087058 | + | ERP44 | chr9 | 102784508 | - |
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FusionProtFeatures for EGFR_ERP44 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| EGFR | ERP44 |
| Mediates thiol-dependent retention in the earlysecretory pathway, forming mixed disulfides with substrateproteins through its conserved CRFS motif. Inhibits the calciumchannel activity of ITPR1. May have a role in the control ofoxidative protein folding in the endoplasmic reticulum. Requiredto retain ERO1A and ERO1B in the endoplasmic reticulum.{ECO:0000269|PubMed:11847130, ECO:0000269|PubMed:14517240}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >ERP44 | chr7:55087058 | chr9:102784508 | ENST00000262455 | - | 3 | 12 | 403_406 | 95 | 407 | Motif | Prevents secretion from ER |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000275493 | + | 1 | 28 | 712_979 | 29 | 1211 | Domain | Protein kinase |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000342916 | + | 1 | 16 | 712_979 | 29 | 629 | Domain | Protein kinase |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000344576 | + | 1 | 16 | 712_979 | 29 | 706 | Domain | Protein kinase |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000420316 | + | 1 | 10 | 712_979 | 29 | 406 | Domain | Protein kinase |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000275493 | + | 1 | 28 | 718_726 | 29 | 1211 | Nucleotide binding | ATP |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000275493 | + | 1 | 28 | 790_791 | 29 | 1211 | Nucleotide binding | ATP |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000342916 | + | 1 | 16 | 718_726 | 29 | 629 | Nucleotide binding | ATP |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000342916 | + | 1 | 16 | 790_791 | 29 | 629 | Nucleotide binding | ATP |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000344576 | + | 1 | 16 | 718_726 | 29 | 706 | Nucleotide binding | ATP |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000344576 | + | 1 | 16 | 790_791 | 29 | 706 | Nucleotide binding | ATP |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000420316 | + | 1 | 10 | 718_726 | 29 | 406 | Nucleotide binding | ATP |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000420316 | + | 1 | 10 | 790_791 | 29 | 406 | Nucleotide binding | ATP |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000275493 | + | 1 | 28 | 688_704 | 29 | 1211 | Region | Note=Important for dimerization%2C phosphorylation and activation |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000342916 | + | 1 | 16 | 688_704 | 29 | 629 | Region | Note=Important for dimerization%2C phosphorylation and activation |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000344576 | + | 1 | 16 | 688_704 | 29 | 706 | Region | Note=Important for dimerization%2C phosphorylation and activation |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000420316 | + | 1 | 10 | 688_704 | 29 | 406 | Region | Note=Important for dimerization%2C phosphorylation and activation |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000275493 | + | 1 | 28 | 390_600 | 29 | 1211 | Repeat | Note=Approximate |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000275493 | + | 1 | 28 | 75_300 | 29 | 1211 | Repeat | Note=Approximate |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000342916 | + | 1 | 16 | 390_600 | 29 | 629 | Repeat | Note=Approximate |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000342916 | + | 1 | 16 | 75_300 | 29 | 629 | Repeat | Note=Approximate |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000344576 | + | 1 | 16 | 390_600 | 29 | 706 | Repeat | Note=Approximate |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000344576 | + | 1 | 16 | 75_300 | 29 | 706 | Repeat | Note=Approximate |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000420316 | + | 1 | 10 | 390_600 | 29 | 406 | Repeat | Note=Approximate |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000420316 | + | 1 | 10 | 75_300 | 29 | 406 | Repeat | Note=Approximate |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000275493 | + | 1 | 28 | 25_645 | 29 | 1211 | Topological domain | Extracellular |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000275493 | + | 1 | 28 | 669_1210 | 29 | 1211 | Topological domain | Cytoplasmic |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000342916 | + | 1 | 16 | 25_645 | 29 | 629 | Topological domain | Extracellular |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000342916 | + | 1 | 16 | 669_1210 | 29 | 629 | Topological domain | Cytoplasmic |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000344576 | + | 1 | 16 | 25_645 | 29 | 706 | Topological domain | Extracellular |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000344576 | + | 1 | 16 | 669_1210 | 29 | 706 | Topological domain | Cytoplasmic |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000420316 | + | 1 | 10 | 25_645 | 29 | 406 | Topological domain | Extracellular |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000420316 | + | 1 | 10 | 669_1210 | 29 | 406 | Topological domain | Cytoplasmic |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000275493 | + | 1 | 28 | 646_668 | 29 | 1211 | Transmembrane | Helical |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000342916 | + | 1 | 16 | 646_668 | 29 | 629 | Transmembrane | Helical |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000344576 | + | 1 | 16 | 646_668 | 29 | 706 | Transmembrane | Helical |
| Hgene | >EGFR | chr7:55087058 | chr9:102784508 | ENST00000420316 | + | 1 | 10 | 646_668 | 29 | 406 | Transmembrane | Helical |
| Tgene | ERP44 | chr7:55087058 | chr9:102784508 | ENST00000262455 | - | 3 | 12 | 30_138 | 95 | 407 | Domain | Thioredoxin |
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FusionGeneSequence for EGFR_ERP44 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_EGFR_ENST00000455089_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_341aa MRPSGTAGAALLALLAALCPASRALEEKKADIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTL DRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVR EITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFK >In-frame_EGFR_ENST00000342916_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_341aa MRPSGTAGAALLALLAALCPASRALEEKKADIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTL DRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVR EITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFK >In-frame_EGFR_ENST00000344576_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_341aa MRPSGTAGAALLALLAALCPASRALEEKKADIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTL DRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVR EITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFK >In-frame_EGFR_ENST00000420316_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_341aa MRPSGTAGAALLALLAALCPASRALEEKKADIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTL DRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVR EITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFK >In-frame_EGFR_ENST00000275493_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_341aa MRPSGTAGAALLALLAALCPASRALEEKKADIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTL DRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVR EITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFK >In-frame_EGFR_ENST00000442591_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_341aa MRPSGTAGAALLALLAALCPASRALEEKKADIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTL DRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVR EITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_EGFR_ENST00000455089_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_1023nt ATGCGACCCTCCGGGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCT GACATAGCCCAGAGATACAGGATAAGCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAG CGATCAGTGAAAGCATTGGCAGATTACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTT GATCGCAGCAAAAGAAATATCATTGGATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCAT GATGACTGTGCCTTTCTTTCTGCATTTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCAT TCTGCTCCGGATATGGTGTACTTGGGAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGA GAAATAACATTTGAAAATGGAGAGGAATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTA GAAATATTCCAGAATGAAGTAGCTCGGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACAT CCTCTTCTGCACATACAGAAAACTCCAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAA GATGTATTAATTCCTGGAAAACTCAAGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCA ACTGATACAGCCCCAGGAGAGCAAGCCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGG >In-frame_EGFR_ENST00000342916_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_1023nt ATGCGACCCTCCGGGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCT GACATAGCCCAGAGATACAGGATAAGCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAG CGATCAGTGAAAGCATTGGCAGATTACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTT GATCGCAGCAAAAGAAATATCATTGGATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCAT GATGACTGTGCCTTTCTTTCTGCATTTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCAT TCTGCTCCGGATATGGTGTACTTGGGAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGA GAAATAACATTTGAAAATGGAGAGGAATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTA GAAATATTCCAGAATGAAGTAGCTCGGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACAT CCTCTTCTGCACATACAGAAAACTCCAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAA GATGTATTAATTCCTGGAAAACTCAAGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCA ACTGATACAGCCCCAGGAGAGCAAGCCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGG >In-frame_EGFR_ENST00000344576_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_1023nt ATGCGACCCTCCGGGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCT GACATAGCCCAGAGATACAGGATAAGCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAG CGATCAGTGAAAGCATTGGCAGATTACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTT GATCGCAGCAAAAGAAATATCATTGGATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCAT GATGACTGTGCCTTTCTTTCTGCATTTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCAT TCTGCTCCGGATATGGTGTACTTGGGAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGA GAAATAACATTTGAAAATGGAGAGGAATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTA GAAATATTCCAGAATGAAGTAGCTCGGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACAT CCTCTTCTGCACATACAGAAAACTCCAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAA GATGTATTAATTCCTGGAAAACTCAAGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCA ACTGATACAGCCCCAGGAGAGCAAGCCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGG >In-frame_EGFR_ENST00000420316_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_1023nt ATGCGACCCTCCGGGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCT GACATAGCCCAGAGATACAGGATAAGCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAG CGATCAGTGAAAGCATTGGCAGATTACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTT GATCGCAGCAAAAGAAATATCATTGGATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCAT GATGACTGTGCCTTTCTTTCTGCATTTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCAT TCTGCTCCGGATATGGTGTACTTGGGAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGA GAAATAACATTTGAAAATGGAGAGGAATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTA GAAATATTCCAGAATGAAGTAGCTCGGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACAT CCTCTTCTGCACATACAGAAAACTCCAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAA GATGTATTAATTCCTGGAAAACTCAAGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCA ACTGATACAGCCCCAGGAGAGCAAGCCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGG >In-frame_EGFR_ENST00000275493_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_1023nt ATGCGACCCTCCGGGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCT GACATAGCCCAGAGATACAGGATAAGCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAG CGATCAGTGAAAGCATTGGCAGATTACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTT GATCGCAGCAAAAGAAATATCATTGGATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCAT GATGACTGTGCCTTTCTTTCTGCATTTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCAT TCTGCTCCGGATATGGTGTACTTGGGAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGA GAAATAACATTTGAAAATGGAGAGGAATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTA GAAATATTCCAGAATGAAGTAGCTCGGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACAT CCTCTTCTGCACATACAGAAAACTCCAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAA GATGTATTAATTCCTGGAAAACTCAAGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCA ACTGATACAGCCCCAGGAGAGCAAGCCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGG >In-frame_EGFR_ENST00000442591_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_1023nt ATGCGACCCTCCGGGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCT GACATAGCCCAGAGATACAGGATAAGCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAG CGATCAGTGAAAGCATTGGCAGATTACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTT GATCGCAGCAAAAGAAATATCATTGGATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCAT GATGACTGTGCCTTTCTTTCTGCATTTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCAT TCTGCTCCGGATATGGTGTACTTGGGAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGA GAAATAACATTTGAAAATGGAGAGGAATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTA GAAATATTCCAGAATGAAGTAGCTCGGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACAT CCTCTTCTGCACATACAGAAAACTCCAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAA GATGTATTAATTCCTGGAAAACTCAAGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCA ACTGATACAGCCCCAGGAGAGCAAGCCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_EGFR_ENST00000455089_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_4713nt GTCCGGGCAGCCCCCGGCGCAGCGCGGCCGCAGCAGCCTCCGCCCCCCGCACGGTGTGAGCGCCCGACGCGGCCGAGGCGGCCGGAGTCC CGAGCTAGCCCCGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCC ACAACCACCGCGCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCG GGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCTGACATAGCCCAGA GATACAGGATAAGCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAGCGATCAGTGAAAG CATTGGCAGATTACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTTGATCGCAGCAAAA GAAATATCATTGGATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCATGATGACTGTGCCT TTCTTTCTGCATTTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCATTCTGCTCCGGATA TGGTGTACTTGGGAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGAGAAATAACATTTG AAAATGGAGAGGAATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTAGAAATATTCCAGA ATGAAGTAGCTCGGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACATCCTCTTCTGCACA TACAGAAAACTCCAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAAGATGTATTAATTC CTGGAAAACTCAAGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCAACTGATACAGCCC CAGGAGAGCAAGCCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGGTATACTCTATTGA GGGATCGAGATGAGCTTTAAAAACTTGAAAAACAGTTTGTAAGCCTTTCAACAGCAGCATCAACCTACGTGGTGGAAATAGTAAACCTAT ATTTTCATAATTCTATGTGTATTTTTATTTTGAATAAACAGAAAGAAATTTTGGGTTTTTAATTTTTTTCTCCCCGACTCAAAATGCATT GTCATTTAATATAGTAGCCTCTTAAAAAAAAAAAACCTGCTAGGATTTAAAAATAAAAATCAGAGGCCTATCTCCACTTTAAATCTGTCC TGTAAAAGTTTTATAAATCAAATGAAAGGTGACATTGCCAGAAACTTACCATTAACTTGCACTACTAGGGTAGGGAGGACTTAGGGATGT TTCCTGTGTCGTATGTGCTTTTCTTTCTTTCATATGATCAATTCTGTTGGTATTTTCAGTATCTCATTTCTCAAAGCTAAAGAGATATAC ATTCTGGATACTTGGGAGGGGAATAAATTAAAGTTTTCACACTGTGTACTGTGTTTTACTGATTGGTTGGATATTGCTTATGAAAATTCC ATAGTGGTATTTTTTTGGATTCTTAATGTGTAACTTAAACATACTTTGAAGTGGAGGAGAGTCATAAGACAGAACATTTGGCAGGAATTG TCCTTATGAAACAAGAAAAAGAAAATGAAAAGTATTATTAAGCTTCTGTGTTTGTCTAAAAATGTGGCATATGGATGGCATTTAAAACTT TGAATGAATTATACCTAAATCTGGGACAGGGAGGTGACAGTGGAACAGGCTACCAATCAGAACTAGATGACTTTTAAGGCTCCTCCTATT ATGAGACTTCAATTTCCAAAGAGAAGAACTAGCAGAGAAATTGTATTTCAGTAATTTTAAGCTCCTTCTGTCTTGTAGAGTCTTGTTATA GTTGTATAAATCAAAAACACAGAATAAGGAACATATTTAACTTTTTTTCATTATAAAATGGTTAGAGGACCCTACCCCCTCTAGATTCCC TGATTTCCCCAGGCCTGCAGCATACAGTAAGATGGGTCCCTGTGCCAGGCCTCAATACTGCCAGGGAATAAAACCAGAGGGAGAGGACCC TCAGTGTCATATCAGGAAGCCCAGTGCCAGAGGACAGACAGGTTCAAAACTGGCTTTTCCTCTGGGCCTGGGTTGGTGCTATAGGCCAAG GGTCATTTTATACTTGGGTATAAATCAATCCCAGTTTGGGAAAAGATTATTTTTAAGCTTAAAAGGCTGACATGTGCCATTATATGTAGT ATGTAATATATGTAACATCTTCCAATTCTTTTAAAATAAAATTAATATTTATAATGGATATTTAATGATTGTTATTTTTAAAAACCAGCT TATAATTCCTCGTTATGCATGATTTATCCAAAGTTTCCATAGTTTTATTCAAAATAATAAATGTTAATAAGGTGATAAGGGGTATATTTA ATGTATTGTATCAAATTGTGAATAAGAAAGTAGGATGGAGCTTTCTAGAGGTTGGGCCTTAGTTCTGTTATCCTCATTGCTTTTAACCAA TAAGTTAAATGAAGTTAGAGTTATGGTCTTCAGGTTAGATTATGGACCAGATCTGTGAGGGTCAGCATGGAAATTCACATTCAACAAGGT AGCACACAGGACCAAGAGCAGCACATGCAATCAACTGGAATAATATAGTAATCCTGTAACTGGGTTTGAAAAAATAATCAACAAAAGATA CAATTCAAGGGTTAGGTTGCAGAGAGCTGGCTTGAGAGTAGTTATTATGAAAAAGGCCTCAAGGAGTACGTGTTCAGTATGCTCTAAGAT GATAAAGTGGCTGTTAAAAAGGGAGTTGATTTGAGGAAGTATTACTTAGCATTCATGCATATTGGGCTTAGGCTCTAGCCCTGCCACTAT CATTGTCTTCTCTGGACTGTGAAGTCACTGAGGACAAGGAAACTAAATTTAATGTCTGTATCACTAGTGCCTAGAATTTCTGGACACTTA GTAGTCACCATCAGGCGTTTATTTAATGAATGAGAAGCAAAGTGACCTTGGTTACTTTTTTACCCTGAGGGGCTCAGCACTCATTAGGAC TTGGTGCCTAATTTTATAAAAAGTCACTAAGCTCAAGTGCTTGGATGAAAGGACAGCGTGGATAAAAAGGTTTTTAAAACATGGATGTTA AGGCTGTTTTGCTTGGAGAAGACTTGGGACTGGGACAGTCTTTAGATATTATTTGAAATGCTGGCACTGTCTATCTGGATCCCAGGGCTT GAACTAGGATTTGAGGAAGTCACAGGGAAGCAGATTTCAGTCTGACATTTATTCAGTGCAAGTTTTTTGGTGCTGTAGTATATGATGAAA GATGTAAAGCTGAATAAAGCATTATTTCTGCCCTAGAGTTGTTCACAGCCTAGTCAGGCATATGGATATGTAAACAATGACTGTAACGTG TTATAGATGTAAAGACAAAATAAAGGTTAAAGAGGGCATAAAGGAGCACTCAATTGCAGAGATTTGAGGACATTATTTTTATTTTGAGCT TTAAAAAGATGAATAGGTGTTCTCAGGAGGTAGGGATCTGGCTGAGAGGGAATAATCTGAGCAAAGGTATGAAACAGCCTAATGCATTAG AGAAAAAAGTTCTTTTAGTAAGGCATTTGGGGTTGGGGAAGCTAGAAAAAGAAATGGGAGCTGGTCACACAGGGCCTTGTGTGCCAGACT AAGGGGTTTGTAGTATATATTGTAGGCAGAAGAGATCCATCAACAGATTGCAAGCAAGGAAGTATGTTCACTTTAAAGTTTGAGAAAGAA TAGTGTGGAAGCACGTCTCAAATTTAGACTTGTTCCCCCTCTGAACCGTGAATCAGACCATTTCAGGTAGAAGTCTTCCCCGGTTTATCT GATCTACTCGGGGCCTCAGGCTTCTCAGCTGGGAAGAGAGGATGCAAGACCAGACTGAAGAACACGGTTGAGTCCCCAGAACCAAAAGGG GGCCTTTCTGCTTCTTAGCCAGCTACCTCTTCGAGTTTTTCAAATTGTGAGGGGGACCATAAAAGGATGGAAACTTTTAGATGACATTCT ACAAATTATTTTTTTCTTTAAATTAAAAGAACCTAGCCAATAAGATAGAGAATGGGCATCTAAGGCATCTCAGAGCTCTCTGATGAAGCC AGGTTGTCAAAGATCATTTGCAAAAGAAGGGAAAACTGGCATGACAAAAGCTACAGAGAGGAGAGTGAAATATAGAAGTGTTTGAAATGT TCAAGCTCACAATAAGCTTAAATTTATAGAAAATGCTAAGGTTGTCAAGAAGGCTTTTTTTTTTTTCTTTTTTAAACCTGAGGGCAAAAA GGAATGGATAAAGTAGTGTAATGGATTGACAATCAGGAAGAACAGAATAACTCAGTTTTTTTTCTCCTACAAGGAGATATGGCTGGACCA >In-frame_EGFR_ENST00000342916_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_4702nt CCCCGGCGCAGCGCGGCCGCAGCAGCCTCCGCCCCCCGCACGGTGTGAGCGCCCGACGCGGCCGAGGCGGCCGGAGTCCCGAGCTAGCCC CGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCCACAACCACCGC GCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCGGGACGGCCGGG GCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCTGACATAGCCCAGAGATACAGGATA AGCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAGCGATCAGTGAAAGCATTGGCAGAT TACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTTGATCGCAGCAAAAGAAATATCATT GGATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCATGATGACTGTGCCTTTCTTTCTGCA TTTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCATTCTGCTCCGGATATGGTGTACTTG GGAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGAGAAATAACATTTGAAAATGGAGAG GAATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTAGAAATATTCCAGAATGAAGTAGCT CGGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACATCCTCTTCTGCACATACAGAAAACT CCAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAAGATGTATTAATTCCTGGAAAACTC AAGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCAACTGATACAGCCCCAGGAGAGCAA GCCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGGTATACTCTATTGAGGGATCGAGAT GAGCTTTAAAAACTTGAAAAACAGTTTGTAAGCCTTTCAACAGCAGCATCAACCTACGTGGTGGAAATAGTAAACCTATATTTTCATAAT TCTATGTGTATTTTTATTTTGAATAAACAGAAAGAAATTTTGGGTTTTTAATTTTTTTCTCCCCGACTCAAAATGCATTGTCATTTAATA TAGTAGCCTCTTAAAAAAAAAAAACCTGCTAGGATTTAAAAATAAAAATCAGAGGCCTATCTCCACTTTAAATCTGTCCTGTAAAAGTTT TATAAATCAAATGAAAGGTGACATTGCCAGAAACTTACCATTAACTTGCACTACTAGGGTAGGGAGGACTTAGGGATGTTTCCTGTGTCG TATGTGCTTTTCTTTCTTTCATATGATCAATTCTGTTGGTATTTTCAGTATCTCATTTCTCAAAGCTAAAGAGATATACATTCTGGATAC TTGGGAGGGGAATAAATTAAAGTTTTCACACTGTGTACTGTGTTTTACTGATTGGTTGGATATTGCTTATGAAAATTCCATAGTGGTATT TTTTTGGATTCTTAATGTGTAACTTAAACATACTTTGAAGTGGAGGAGAGTCATAAGACAGAACATTTGGCAGGAATTGTCCTTATGAAA CAAGAAAAAGAAAATGAAAAGTATTATTAAGCTTCTGTGTTTGTCTAAAAATGTGGCATATGGATGGCATTTAAAACTTTGAATGAATTA TACCTAAATCTGGGACAGGGAGGTGACAGTGGAACAGGCTACCAATCAGAACTAGATGACTTTTAAGGCTCCTCCTATTATGAGACTTCA ATTTCCAAAGAGAAGAACTAGCAGAGAAATTGTATTTCAGTAATTTTAAGCTCCTTCTGTCTTGTAGAGTCTTGTTATAGTTGTATAAAT CAAAAACACAGAATAAGGAACATATTTAACTTTTTTTCATTATAAAATGGTTAGAGGACCCTACCCCCTCTAGATTCCCTGATTTCCCCA GGCCTGCAGCATACAGTAAGATGGGTCCCTGTGCCAGGCCTCAATACTGCCAGGGAATAAAACCAGAGGGAGAGGACCCTCAGTGTCATA TCAGGAAGCCCAGTGCCAGAGGACAGACAGGTTCAAAACTGGCTTTTCCTCTGGGCCTGGGTTGGTGCTATAGGCCAAGGGTCATTTTAT ACTTGGGTATAAATCAATCCCAGTTTGGGAAAAGATTATTTTTAAGCTTAAAAGGCTGACATGTGCCATTATATGTAGTATGTAATATAT GTAACATCTTCCAATTCTTTTAAAATAAAATTAATATTTATAATGGATATTTAATGATTGTTATTTTTAAAAACCAGCTTATAATTCCTC GTTATGCATGATTTATCCAAAGTTTCCATAGTTTTATTCAAAATAATAAATGTTAATAAGGTGATAAGGGGTATATTTAATGTATTGTAT CAAATTGTGAATAAGAAAGTAGGATGGAGCTTTCTAGAGGTTGGGCCTTAGTTCTGTTATCCTCATTGCTTTTAACCAATAAGTTAAATG AAGTTAGAGTTATGGTCTTCAGGTTAGATTATGGACCAGATCTGTGAGGGTCAGCATGGAAATTCACATTCAACAAGGTAGCACACAGGA CCAAGAGCAGCACATGCAATCAACTGGAATAATATAGTAATCCTGTAACTGGGTTTGAAAAAATAATCAACAAAAGATACAATTCAAGGG TTAGGTTGCAGAGAGCTGGCTTGAGAGTAGTTATTATGAAAAAGGCCTCAAGGAGTACGTGTTCAGTATGCTCTAAGATGATAAAGTGGC TGTTAAAAAGGGAGTTGATTTGAGGAAGTATTACTTAGCATTCATGCATATTGGGCTTAGGCTCTAGCCCTGCCACTATCATTGTCTTCT CTGGACTGTGAAGTCACTGAGGACAAGGAAACTAAATTTAATGTCTGTATCACTAGTGCCTAGAATTTCTGGACACTTAGTAGTCACCAT CAGGCGTTTATTTAATGAATGAGAAGCAAAGTGACCTTGGTTACTTTTTTACCCTGAGGGGCTCAGCACTCATTAGGACTTGGTGCCTAA TTTTATAAAAAGTCACTAAGCTCAAGTGCTTGGATGAAAGGACAGCGTGGATAAAAAGGTTTTTAAAACATGGATGTTAAGGCTGTTTTG CTTGGAGAAGACTTGGGACTGGGACAGTCTTTAGATATTATTTGAAATGCTGGCACTGTCTATCTGGATCCCAGGGCTTGAACTAGGATT TGAGGAAGTCACAGGGAAGCAGATTTCAGTCTGACATTTATTCAGTGCAAGTTTTTTGGTGCTGTAGTATATGATGAAAGATGTAAAGCT GAATAAAGCATTATTTCTGCCCTAGAGTTGTTCACAGCCTAGTCAGGCATATGGATATGTAAACAATGACTGTAACGTGTTATAGATGTA AAGACAAAATAAAGGTTAAAGAGGGCATAAAGGAGCACTCAATTGCAGAGATTTGAGGACATTATTTTTATTTTGAGCTTTAAAAAGATG AATAGGTGTTCTCAGGAGGTAGGGATCTGGCTGAGAGGGAATAATCTGAGCAAAGGTATGAAACAGCCTAATGCATTAGAGAAAAAAGTT CTTTTAGTAAGGCATTTGGGGTTGGGGAAGCTAGAAAAAGAAATGGGAGCTGGTCACACAGGGCCTTGTGTGCCAGACTAAGGGGTTTGT AGTATATATTGTAGGCAGAAGAGATCCATCAACAGATTGCAAGCAAGGAAGTATGTTCACTTTAAAGTTTGAGAAAGAATAGTGTGGAAG CACGTCTCAAATTTAGACTTGTTCCCCCTCTGAACCGTGAATCAGACCATTTCAGGTAGAAGTCTTCCCCGGTTTATCTGATCTACTCGG GGCCTCAGGCTTCTCAGCTGGGAAGAGAGGATGCAAGACCAGACTGAAGAACACGGTTGAGTCCCCAGAACCAAAAGGGGGCCTTTCTGC TTCTTAGCCAGCTACCTCTTCGAGTTTTTCAAATTGTGAGGGGGACCATAAAAGGATGGAAACTTTTAGATGACATTCTACAAATTATTT TTTTCTTTAAATTAAAAGAACCTAGCCAATAAGATAGAGAATGGGCATCTAAGGCATCTCAGAGCTCTCTGATGAAGCCAGGTTGTCAAA GATCATTTGCAAAAGAAGGGAAAACTGGCATGACAAAAGCTACAGAGAGGAGAGTGAAATATAGAAGTGTTTGAAATGTTCAAGCTCACA ATAAGCTTAAATTTATAGAAAATGCTAAGGTTGTCAAGAAGGCTTTTTTTTTTTTCTTTTTTAAACCTGAGGGCAAAAAGGAATGGATAA AGTAGTGTAATGGATTGACAATCAGGAAGAACAGAATAACTCAGTTTTTTTTCTCCTACAAGGAGATATGGCTGGACCAAAATAAAATGA >In-frame_EGFR_ENST00000344576_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_4701nt CCCGGCGCAGCGCGGCCGCAGCAGCCTCCGCCCCCCGCACGGTGTGAGCGCCCGACGCGGCCGAGGCGGCCGGAGTCCCGAGCTAGCCCC GGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCCACAACCACCGCG CACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCGGGACGGCCGGGG CAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCTGACATAGCCCAGAGATACAGGATAA GCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAGCGATCAGTGAAAGCATTGGCAGATT ACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTTGATCGCAGCAAAAGAAATATCATTG GATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCATGATGACTGTGCCTTTCTTTCTGCAT TTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCATTCTGCTCCGGATATGGTGTACTTGG GAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGAGAAATAACATTTGAAAATGGAGAGG AATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTAGAAATATTCCAGAATGAAGTAGCTC GGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACATCCTCTTCTGCACATACAGAAAACTC CAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAAGATGTATTAATTCCTGGAAAACTCA AGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCAACTGATACAGCCCCAGGAGAGCAAG CCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGGTATACTCTATTGAGGGATCGAGATG AGCTTTAAAAACTTGAAAAACAGTTTGTAAGCCTTTCAACAGCAGCATCAACCTACGTGGTGGAAATAGTAAACCTATATTTTCATAATT CTATGTGTATTTTTATTTTGAATAAACAGAAAGAAATTTTGGGTTTTTAATTTTTTTCTCCCCGACTCAAAATGCATTGTCATTTAATAT AGTAGCCTCTTAAAAAAAAAAAACCTGCTAGGATTTAAAAATAAAAATCAGAGGCCTATCTCCACTTTAAATCTGTCCTGTAAAAGTTTT ATAAATCAAATGAAAGGTGACATTGCCAGAAACTTACCATTAACTTGCACTACTAGGGTAGGGAGGACTTAGGGATGTTTCCTGTGTCGT ATGTGCTTTTCTTTCTTTCATATGATCAATTCTGTTGGTATTTTCAGTATCTCATTTCTCAAAGCTAAAGAGATATACATTCTGGATACT TGGGAGGGGAATAAATTAAAGTTTTCACACTGTGTACTGTGTTTTACTGATTGGTTGGATATTGCTTATGAAAATTCCATAGTGGTATTT TTTTGGATTCTTAATGTGTAACTTAAACATACTTTGAAGTGGAGGAGAGTCATAAGACAGAACATTTGGCAGGAATTGTCCTTATGAAAC AAGAAAAAGAAAATGAAAAGTATTATTAAGCTTCTGTGTTTGTCTAAAAATGTGGCATATGGATGGCATTTAAAACTTTGAATGAATTAT ACCTAAATCTGGGACAGGGAGGTGACAGTGGAACAGGCTACCAATCAGAACTAGATGACTTTTAAGGCTCCTCCTATTATGAGACTTCAA TTTCCAAAGAGAAGAACTAGCAGAGAAATTGTATTTCAGTAATTTTAAGCTCCTTCTGTCTTGTAGAGTCTTGTTATAGTTGTATAAATC AAAAACACAGAATAAGGAACATATTTAACTTTTTTTCATTATAAAATGGTTAGAGGACCCTACCCCCTCTAGATTCCCTGATTTCCCCAG GCCTGCAGCATACAGTAAGATGGGTCCCTGTGCCAGGCCTCAATACTGCCAGGGAATAAAACCAGAGGGAGAGGACCCTCAGTGTCATAT CAGGAAGCCCAGTGCCAGAGGACAGACAGGTTCAAAACTGGCTTTTCCTCTGGGCCTGGGTTGGTGCTATAGGCCAAGGGTCATTTTATA CTTGGGTATAAATCAATCCCAGTTTGGGAAAAGATTATTTTTAAGCTTAAAAGGCTGACATGTGCCATTATATGTAGTATGTAATATATG TAACATCTTCCAATTCTTTTAAAATAAAATTAATATTTATAATGGATATTTAATGATTGTTATTTTTAAAAACCAGCTTATAATTCCTCG TTATGCATGATTTATCCAAAGTTTCCATAGTTTTATTCAAAATAATAAATGTTAATAAGGTGATAAGGGGTATATTTAATGTATTGTATC AAATTGTGAATAAGAAAGTAGGATGGAGCTTTCTAGAGGTTGGGCCTTAGTTCTGTTATCCTCATTGCTTTTAACCAATAAGTTAAATGA AGTTAGAGTTATGGTCTTCAGGTTAGATTATGGACCAGATCTGTGAGGGTCAGCATGGAAATTCACATTCAACAAGGTAGCACACAGGAC CAAGAGCAGCACATGCAATCAACTGGAATAATATAGTAATCCTGTAACTGGGTTTGAAAAAATAATCAACAAAAGATACAATTCAAGGGT TAGGTTGCAGAGAGCTGGCTTGAGAGTAGTTATTATGAAAAAGGCCTCAAGGAGTACGTGTTCAGTATGCTCTAAGATGATAAAGTGGCT GTTAAAAAGGGAGTTGATTTGAGGAAGTATTACTTAGCATTCATGCATATTGGGCTTAGGCTCTAGCCCTGCCACTATCATTGTCTTCTC TGGACTGTGAAGTCACTGAGGACAAGGAAACTAAATTTAATGTCTGTATCACTAGTGCCTAGAATTTCTGGACACTTAGTAGTCACCATC AGGCGTTTATTTAATGAATGAGAAGCAAAGTGACCTTGGTTACTTTTTTACCCTGAGGGGCTCAGCACTCATTAGGACTTGGTGCCTAAT TTTATAAAAAGTCACTAAGCTCAAGTGCTTGGATGAAAGGACAGCGTGGATAAAAAGGTTTTTAAAACATGGATGTTAAGGCTGTTTTGC TTGGAGAAGACTTGGGACTGGGACAGTCTTTAGATATTATTTGAAATGCTGGCACTGTCTATCTGGATCCCAGGGCTTGAACTAGGATTT GAGGAAGTCACAGGGAAGCAGATTTCAGTCTGACATTTATTCAGTGCAAGTTTTTTGGTGCTGTAGTATATGATGAAAGATGTAAAGCTG AATAAAGCATTATTTCTGCCCTAGAGTTGTTCACAGCCTAGTCAGGCATATGGATATGTAAACAATGACTGTAACGTGTTATAGATGTAA AGACAAAATAAAGGTTAAAGAGGGCATAAAGGAGCACTCAATTGCAGAGATTTGAGGACATTATTTTTATTTTGAGCTTTAAAAAGATGA ATAGGTGTTCTCAGGAGGTAGGGATCTGGCTGAGAGGGAATAATCTGAGCAAAGGTATGAAACAGCCTAATGCATTAGAGAAAAAAGTTC TTTTAGTAAGGCATTTGGGGTTGGGGAAGCTAGAAAAAGAAATGGGAGCTGGTCACACAGGGCCTTGTGTGCCAGACTAAGGGGTTTGTA GTATATATTGTAGGCAGAAGAGATCCATCAACAGATTGCAAGCAAGGAAGTATGTTCACTTTAAAGTTTGAGAAAGAATAGTGTGGAAGC ACGTCTCAAATTTAGACTTGTTCCCCCTCTGAACCGTGAATCAGACCATTTCAGGTAGAAGTCTTCCCCGGTTTATCTGATCTACTCGGG GCCTCAGGCTTCTCAGCTGGGAAGAGAGGATGCAAGACCAGACTGAAGAACACGGTTGAGTCCCCAGAACCAAAAGGGGGCCTTTCTGCT TCTTAGCCAGCTACCTCTTCGAGTTTTTCAAATTGTGAGGGGGACCATAAAAGGATGGAAACTTTTAGATGACATTCTACAAATTATTTT TTTCTTTAAATTAAAAGAACCTAGCCAATAAGATAGAGAATGGGCATCTAAGGCATCTCAGAGCTCTCTGATGAAGCCAGGTTGTCAAAG ATCATTTGCAAAAGAAGGGAAAACTGGCATGACAAAAGCTACAGAGAGGAGAGTGAAATATAGAAGTGTTTGAAATGTTCAAGCTCACAA TAAGCTTAAATTTATAGAAAATGCTAAGGTTGTCAAGAAGGCTTTTTTTTTTTTCTTTTTTAAACCTGAGGGCAAAAAGGAATGGATAAA GTAGTGTAATGGATTGACAATCAGGAAGAACAGAATAACTCAGTTTTTTTTCTCCTACAAGGAGATATGGCTGGACCAAAATAAAATGAC >In-frame_EGFR_ENST00000420316_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_4700nt CCGGCGCAGCGCGGCCGCAGCAGCCTCCGCCCCCCGCACGGTGTGAGCGCCCGACGCGGCCGAGGCGGCCGGAGTCCCGAGCTAGCCCCG GCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCCACAACCACCGCGC ACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCGGGACGGCCGGGGC AGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCTGACATAGCCCAGAGATACAGGATAAG CAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAGCGATCAGTGAAAGCATTGGCAGATTA CATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTTGATCGCAGCAAAAGAAATATCATTGG ATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCATGATGACTGTGCCTTTCTTTCTGCATT TGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCATTCTGCTCCGGATATGGTGTACTTGGG AGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGAGAAATAACATTTGAAAATGGAGAGGA ATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTAGAAATATTCCAGAATGAAGTAGCTCG GCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACATCCTCTTCTGCACATACAGAAAACTCC AGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAAGATGTATTAATTCCTGGAAAACTCAA GCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCAACTGATACAGCCCCAGGAGAGCAAGC CCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGGTATACTCTATTGAGGGATCGAGATGA GCTTTAAAAACTTGAAAAACAGTTTGTAAGCCTTTCAACAGCAGCATCAACCTACGTGGTGGAAATAGTAAACCTATATTTTCATAATTC TATGTGTATTTTTATTTTGAATAAACAGAAAGAAATTTTGGGTTTTTAATTTTTTTCTCCCCGACTCAAAATGCATTGTCATTTAATATA GTAGCCTCTTAAAAAAAAAAAACCTGCTAGGATTTAAAAATAAAAATCAGAGGCCTATCTCCACTTTAAATCTGTCCTGTAAAAGTTTTA TAAATCAAATGAAAGGTGACATTGCCAGAAACTTACCATTAACTTGCACTACTAGGGTAGGGAGGACTTAGGGATGTTTCCTGTGTCGTA TGTGCTTTTCTTTCTTTCATATGATCAATTCTGTTGGTATTTTCAGTATCTCATTTCTCAAAGCTAAAGAGATATACATTCTGGATACTT GGGAGGGGAATAAATTAAAGTTTTCACACTGTGTACTGTGTTTTACTGATTGGTTGGATATTGCTTATGAAAATTCCATAGTGGTATTTT TTTGGATTCTTAATGTGTAACTTAAACATACTTTGAAGTGGAGGAGAGTCATAAGACAGAACATTTGGCAGGAATTGTCCTTATGAAACA AGAAAAAGAAAATGAAAAGTATTATTAAGCTTCTGTGTTTGTCTAAAAATGTGGCATATGGATGGCATTTAAAACTTTGAATGAATTATA CCTAAATCTGGGACAGGGAGGTGACAGTGGAACAGGCTACCAATCAGAACTAGATGACTTTTAAGGCTCCTCCTATTATGAGACTTCAAT TTCCAAAGAGAAGAACTAGCAGAGAAATTGTATTTCAGTAATTTTAAGCTCCTTCTGTCTTGTAGAGTCTTGTTATAGTTGTATAAATCA AAAACACAGAATAAGGAACATATTTAACTTTTTTTCATTATAAAATGGTTAGAGGACCCTACCCCCTCTAGATTCCCTGATTTCCCCAGG CCTGCAGCATACAGTAAGATGGGTCCCTGTGCCAGGCCTCAATACTGCCAGGGAATAAAACCAGAGGGAGAGGACCCTCAGTGTCATATC AGGAAGCCCAGTGCCAGAGGACAGACAGGTTCAAAACTGGCTTTTCCTCTGGGCCTGGGTTGGTGCTATAGGCCAAGGGTCATTTTATAC TTGGGTATAAATCAATCCCAGTTTGGGAAAAGATTATTTTTAAGCTTAAAAGGCTGACATGTGCCATTATATGTAGTATGTAATATATGT AACATCTTCCAATTCTTTTAAAATAAAATTAATATTTATAATGGATATTTAATGATTGTTATTTTTAAAAACCAGCTTATAATTCCTCGT TATGCATGATTTATCCAAAGTTTCCATAGTTTTATTCAAAATAATAAATGTTAATAAGGTGATAAGGGGTATATTTAATGTATTGTATCA AATTGTGAATAAGAAAGTAGGATGGAGCTTTCTAGAGGTTGGGCCTTAGTTCTGTTATCCTCATTGCTTTTAACCAATAAGTTAAATGAA GTTAGAGTTATGGTCTTCAGGTTAGATTATGGACCAGATCTGTGAGGGTCAGCATGGAAATTCACATTCAACAAGGTAGCACACAGGACC AAGAGCAGCACATGCAATCAACTGGAATAATATAGTAATCCTGTAACTGGGTTTGAAAAAATAATCAACAAAAGATACAATTCAAGGGTT AGGTTGCAGAGAGCTGGCTTGAGAGTAGTTATTATGAAAAAGGCCTCAAGGAGTACGTGTTCAGTATGCTCTAAGATGATAAAGTGGCTG TTAAAAAGGGAGTTGATTTGAGGAAGTATTACTTAGCATTCATGCATATTGGGCTTAGGCTCTAGCCCTGCCACTATCATTGTCTTCTCT GGACTGTGAAGTCACTGAGGACAAGGAAACTAAATTTAATGTCTGTATCACTAGTGCCTAGAATTTCTGGACACTTAGTAGTCACCATCA GGCGTTTATTTAATGAATGAGAAGCAAAGTGACCTTGGTTACTTTTTTACCCTGAGGGGCTCAGCACTCATTAGGACTTGGTGCCTAATT TTATAAAAAGTCACTAAGCTCAAGTGCTTGGATGAAAGGACAGCGTGGATAAAAAGGTTTTTAAAACATGGATGTTAAGGCTGTTTTGCT TGGAGAAGACTTGGGACTGGGACAGTCTTTAGATATTATTTGAAATGCTGGCACTGTCTATCTGGATCCCAGGGCTTGAACTAGGATTTG AGGAAGTCACAGGGAAGCAGATTTCAGTCTGACATTTATTCAGTGCAAGTTTTTTGGTGCTGTAGTATATGATGAAAGATGTAAAGCTGA ATAAAGCATTATTTCTGCCCTAGAGTTGTTCACAGCCTAGTCAGGCATATGGATATGTAAACAATGACTGTAACGTGTTATAGATGTAAA GACAAAATAAAGGTTAAAGAGGGCATAAAGGAGCACTCAATTGCAGAGATTTGAGGACATTATTTTTATTTTGAGCTTTAAAAAGATGAA TAGGTGTTCTCAGGAGGTAGGGATCTGGCTGAGAGGGAATAATCTGAGCAAAGGTATGAAACAGCCTAATGCATTAGAGAAAAAAGTTCT TTTAGTAAGGCATTTGGGGTTGGGGAAGCTAGAAAAAGAAATGGGAGCTGGTCACACAGGGCCTTGTGTGCCAGACTAAGGGGTTTGTAG TATATATTGTAGGCAGAAGAGATCCATCAACAGATTGCAAGCAAGGAAGTATGTTCACTTTAAAGTTTGAGAAAGAATAGTGTGGAAGCA CGTCTCAAATTTAGACTTGTTCCCCCTCTGAACCGTGAATCAGACCATTTCAGGTAGAAGTCTTCCCCGGTTTATCTGATCTACTCGGGG CCTCAGGCTTCTCAGCTGGGAAGAGAGGATGCAAGACCAGACTGAAGAACACGGTTGAGTCCCCAGAACCAAAAGGGGGCCTTTCTGCTT CTTAGCCAGCTACCTCTTCGAGTTTTTCAAATTGTGAGGGGGACCATAAAAGGATGGAAACTTTTAGATGACATTCTACAAATTATTTTT TTCTTTAAATTAAAAGAACCTAGCCAATAAGATAGAGAATGGGCATCTAAGGCATCTCAGAGCTCTCTGATGAAGCCAGGTTGTCAAAGA TCATTTGCAAAAGAAGGGAAAACTGGCATGACAAAAGCTACAGAGAGGAGAGTGAAATATAGAAGTGTTTGAAATGTTCAAGCTCACAAT AAGCTTAAATTTATAGAAAATGCTAAGGTTGTCAAGAAGGCTTTTTTTTTTTTCTTTTTTAAACCTGAGGGCAAAAAGGAATGGATAAAG TAGTGTAATGGATTGACAATCAGGAAGAACAGAATAACTCAGTTTTTTTTCTCCTACAAGGAGATATGGCTGGACCAAAATAAAATGACA >In-frame_EGFR_ENST00000275493_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_4633nt GCCGGAGTCCCGAGCTAGCCCCGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGC CGCCAACGCCACAACCACCGCGCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATG CGACCCTCCGGGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCTGAC ATAGCCCAGAGATACAGGATAAGCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAGCGA TCAGTGAAAGCATTGGCAGATTACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTTGAT CGCAGCAAAAGAAATATCATTGGATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCATGAT GACTGTGCCTTTCTTTCTGCATTTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCATTCT GCTCCGGATATGGTGTACTTGGGAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGAGAA ATAACATTTGAAAATGGAGAGGAATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTAGAA ATATTCCAGAATGAAGTAGCTCGGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACATCCT CTTCTGCACATACAGAAAACTCCAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAAGAT GTATTAATTCCTGGAAAACTCAAGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCAACT GATACAGCCCCAGGAGAGCAAGCCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGGTAT ACTCTATTGAGGGATCGAGATGAGCTTTAAAAACTTGAAAAACAGTTTGTAAGCCTTTCAACAGCAGCATCAACCTACGTGGTGGAAATA GTAAACCTATATTTTCATAATTCTATGTGTATTTTTATTTTGAATAAACAGAAAGAAATTTTGGGTTTTTAATTTTTTTCTCCCCGACTC AAAATGCATTGTCATTTAATATAGTAGCCTCTTAAAAAAAAAAAACCTGCTAGGATTTAAAAATAAAAATCAGAGGCCTATCTCCACTTT AAATCTGTCCTGTAAAAGTTTTATAAATCAAATGAAAGGTGACATTGCCAGAAACTTACCATTAACTTGCACTACTAGGGTAGGGAGGAC TTAGGGATGTTTCCTGTGTCGTATGTGCTTTTCTTTCTTTCATATGATCAATTCTGTTGGTATTTTCAGTATCTCATTTCTCAAAGCTAA AGAGATATACATTCTGGATACTTGGGAGGGGAATAAATTAAAGTTTTCACACTGTGTACTGTGTTTTACTGATTGGTTGGATATTGCTTA TGAAAATTCCATAGTGGTATTTTTTTGGATTCTTAATGTGTAACTTAAACATACTTTGAAGTGGAGGAGAGTCATAAGACAGAACATTTG GCAGGAATTGTCCTTATGAAACAAGAAAAAGAAAATGAAAAGTATTATTAAGCTTCTGTGTTTGTCTAAAAATGTGGCATATGGATGGCA TTTAAAACTTTGAATGAATTATACCTAAATCTGGGACAGGGAGGTGACAGTGGAACAGGCTACCAATCAGAACTAGATGACTTTTAAGGC TCCTCCTATTATGAGACTTCAATTTCCAAAGAGAAGAACTAGCAGAGAAATTGTATTTCAGTAATTTTAAGCTCCTTCTGTCTTGTAGAG TCTTGTTATAGTTGTATAAATCAAAAACACAGAATAAGGAACATATTTAACTTTTTTTCATTATAAAATGGTTAGAGGACCCTACCCCCT CTAGATTCCCTGATTTCCCCAGGCCTGCAGCATACAGTAAGATGGGTCCCTGTGCCAGGCCTCAATACTGCCAGGGAATAAAACCAGAGG GAGAGGACCCTCAGTGTCATATCAGGAAGCCCAGTGCCAGAGGACAGACAGGTTCAAAACTGGCTTTTCCTCTGGGCCTGGGTTGGTGCT ATAGGCCAAGGGTCATTTTATACTTGGGTATAAATCAATCCCAGTTTGGGAAAAGATTATTTTTAAGCTTAAAAGGCTGACATGTGCCAT TATATGTAGTATGTAATATATGTAACATCTTCCAATTCTTTTAAAATAAAATTAATATTTATAATGGATATTTAATGATTGTTATTTTTA AAAACCAGCTTATAATTCCTCGTTATGCATGATTTATCCAAAGTTTCCATAGTTTTATTCAAAATAATAAATGTTAATAAGGTGATAAGG GGTATATTTAATGTATTGTATCAAATTGTGAATAAGAAAGTAGGATGGAGCTTTCTAGAGGTTGGGCCTTAGTTCTGTTATCCTCATTGC TTTTAACCAATAAGTTAAATGAAGTTAGAGTTATGGTCTTCAGGTTAGATTATGGACCAGATCTGTGAGGGTCAGCATGGAAATTCACAT TCAACAAGGTAGCACACAGGACCAAGAGCAGCACATGCAATCAACTGGAATAATATAGTAATCCTGTAACTGGGTTTGAAAAAATAATCA ACAAAAGATACAATTCAAGGGTTAGGTTGCAGAGAGCTGGCTTGAGAGTAGTTATTATGAAAAAGGCCTCAAGGAGTACGTGTTCAGTAT GCTCTAAGATGATAAAGTGGCTGTTAAAAAGGGAGTTGATTTGAGGAAGTATTACTTAGCATTCATGCATATTGGGCTTAGGCTCTAGCC CTGCCACTATCATTGTCTTCTCTGGACTGTGAAGTCACTGAGGACAAGGAAACTAAATTTAATGTCTGTATCACTAGTGCCTAGAATTTC TGGACACTTAGTAGTCACCATCAGGCGTTTATTTAATGAATGAGAAGCAAAGTGACCTTGGTTACTTTTTTACCCTGAGGGGCTCAGCAC TCATTAGGACTTGGTGCCTAATTTTATAAAAAGTCACTAAGCTCAAGTGCTTGGATGAAAGGACAGCGTGGATAAAAAGGTTTTTAAAAC ATGGATGTTAAGGCTGTTTTGCTTGGAGAAGACTTGGGACTGGGACAGTCTTTAGATATTATTTGAAATGCTGGCACTGTCTATCTGGAT CCCAGGGCTTGAACTAGGATTTGAGGAAGTCACAGGGAAGCAGATTTCAGTCTGACATTTATTCAGTGCAAGTTTTTTGGTGCTGTAGTA TATGATGAAAGATGTAAAGCTGAATAAAGCATTATTTCTGCCCTAGAGTTGTTCACAGCCTAGTCAGGCATATGGATATGTAAACAATGA CTGTAACGTGTTATAGATGTAAAGACAAAATAAAGGTTAAAGAGGGCATAAAGGAGCACTCAATTGCAGAGATTTGAGGACATTATTTTT ATTTTGAGCTTTAAAAAGATGAATAGGTGTTCTCAGGAGGTAGGGATCTGGCTGAGAGGGAATAATCTGAGCAAAGGTATGAAACAGCCT AATGCATTAGAGAAAAAAGTTCTTTTAGTAAGGCATTTGGGGTTGGGGAAGCTAGAAAAAGAAATGGGAGCTGGTCACACAGGGCCTTGT GTGCCAGACTAAGGGGTTTGTAGTATATATTGTAGGCAGAAGAGATCCATCAACAGATTGCAAGCAAGGAAGTATGTTCACTTTAAAGTT TGAGAAAGAATAGTGTGGAAGCACGTCTCAAATTTAGACTTGTTCCCCCTCTGAACCGTGAATCAGACCATTTCAGGTAGAAGTCTTCCC CGGTTTATCTGATCTACTCGGGGCCTCAGGCTTCTCAGCTGGGAAGAGAGGATGCAAGACCAGACTGAAGAACACGGTTGAGTCCCCAGA ACCAAAAGGGGGCCTTTCTGCTTCTTAGCCAGCTACCTCTTCGAGTTTTTCAAATTGTGAGGGGGACCATAAAAGGATGGAAACTTTTAG ATGACATTCTACAAATTATTTTTTTCTTTAAATTAAAAGAACCTAGCCAATAAGATAGAGAATGGGCATCTAAGGCATCTCAGAGCTCTC TGATGAAGCCAGGTTGTCAAAGATCATTTGCAAAAGAAGGGAAAACTGGCATGACAAAAGCTACAGAGAGGAGAGTGAAATATAGAAGTG TTTGAAATGTTCAAGCTCACAATAAGCTTAAATTTATAGAAAATGCTAAGGTTGTCAAGAAGGCTTTTTTTTTTTTCTTTTTTAAACCTG AGGGCAAAAAGGAATGGATAAAGTAGTGTAATGGATTGACAATCAGGAAGAACAGAATAACTCAGTTTTTTTTCTCCTACAAGGAGATAT >In-frame_EGFR_ENST00000442591_chr7_55087058_+_ERP44_ENST00000262455_chr9_102784508_-_4616nt GCCCCGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCCACAACCA CCGCGCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCGGGACGGC CGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGCTGACATAGCCCAGAGATACAG GATAAGCAAATACCCAACCCTCAAATTGTTTCGTAATGGGATGATGATGAAGAGAGAATACAGGGGTCAGCGATCAGTGAAAGCATTGGC AGATTACATCAGGCAACAAAAAAGTGACCCCATTCAAGAAATTCGGGACTTAGCAGAAATCACCACTCTTGATCGCAGCAAAAGAAATAT CATTGGATATTTTGAGCAAAAGGACTCGGACAACTATAGAGTTTTTGAACGAGTAGCGAATATTTTGCATGATGACTGTGCCTTTCTTTC TGCATTTGGGGATGTTTCAAAACCGGAAAGATATAGTGGCGACAACATAATCTACAAACCACCAGGGCATTCTGCTCCGGATATGGTGTA CTTGGGAGCTATGACAAATTTTGATGTGACTTACAATTGGATTCAAGATAAATGTGTTCCTCTTGTCCGAGAAATAACATTTGAAAATGG AGAGGAATTGACAGAAGAAGGACTGCCTTTTCTCATACTCTTTCACATGAAAGAAGATACAGAAAGTTTAGAAATATTCCAGAATGAAGT AGCTCGGCAATTAATAAGTGAAAAAGGTACAATAAACTTTTTACATGCCGATTGTGACAAATTTAGACATCCTCTTCTGCACATACAGAA AACTCCAGCAGATTGTCCTGTAATCGCTATTGACAGCTTTAGGCATATGTATGTGTTTGGAGACTTCAAAGATGTATTAATTCCTGGAAA ACTCAAGCAATTCGTATTTGACTTACATTCTGGAAAACTGCACAGAGAATTCCATCATGGACCTGACCCAACTGATACAGCCCCAGGAGA GCAAGCCCAAGATGTAGCAAGCAGTCCACCTGAGAGCTCCTTCCAGAAACTAGCACCCAGTGAATATAGGTATACTCTATTGAGGGATCG AGATGAGCTTTAAAAACTTGAAAAACAGTTTGTAAGCCTTTCAACAGCAGCATCAACCTACGTGGTGGAAATAGTAAACCTATATTTTCA TAATTCTATGTGTATTTTTATTTTGAATAAACAGAAAGAAATTTTGGGTTTTTAATTTTTTTCTCCCCGACTCAAAATGCATTGTCATTT AATATAGTAGCCTCTTAAAAAAAAAAAACCTGCTAGGATTTAAAAATAAAAATCAGAGGCCTATCTCCACTTTAAATCTGTCCTGTAAAA GTTTTATAAATCAAATGAAAGGTGACATTGCCAGAAACTTACCATTAACTTGCACTACTAGGGTAGGGAGGACTTAGGGATGTTTCCTGT GTCGTATGTGCTTTTCTTTCTTTCATATGATCAATTCTGTTGGTATTTTCAGTATCTCATTTCTCAAAGCTAAAGAGATATACATTCTGG ATACTTGGGAGGGGAATAAATTAAAGTTTTCACACTGTGTACTGTGTTTTACTGATTGGTTGGATATTGCTTATGAAAATTCCATAGTGG TATTTTTTTGGATTCTTAATGTGTAACTTAAACATACTTTGAAGTGGAGGAGAGTCATAAGACAGAACATTTGGCAGGAATTGTCCTTAT GAAACAAGAAAAAGAAAATGAAAAGTATTATTAAGCTTCTGTGTTTGTCTAAAAATGTGGCATATGGATGGCATTTAAAACTTTGAATGA ATTATACCTAAATCTGGGACAGGGAGGTGACAGTGGAACAGGCTACCAATCAGAACTAGATGACTTTTAAGGCTCCTCCTATTATGAGAC TTCAATTTCCAAAGAGAAGAACTAGCAGAGAAATTGTATTTCAGTAATTTTAAGCTCCTTCTGTCTTGTAGAGTCTTGTTATAGTTGTAT AAATCAAAAACACAGAATAAGGAACATATTTAACTTTTTTTCATTATAAAATGGTTAGAGGACCCTACCCCCTCTAGATTCCCTGATTTC CCCAGGCCTGCAGCATACAGTAAGATGGGTCCCTGTGCCAGGCCTCAATACTGCCAGGGAATAAAACCAGAGGGAGAGGACCCTCAGTGT CATATCAGGAAGCCCAGTGCCAGAGGACAGACAGGTTCAAAACTGGCTTTTCCTCTGGGCCTGGGTTGGTGCTATAGGCCAAGGGTCATT TTATACTTGGGTATAAATCAATCCCAGTTTGGGAAAAGATTATTTTTAAGCTTAAAAGGCTGACATGTGCCATTATATGTAGTATGTAAT ATATGTAACATCTTCCAATTCTTTTAAAATAAAATTAATATTTATAATGGATATTTAATGATTGTTATTTTTAAAAACCAGCTTATAATT CCTCGTTATGCATGATTTATCCAAAGTTTCCATAGTTTTATTCAAAATAATAAATGTTAATAAGGTGATAAGGGGTATATTTAATGTATT GTATCAAATTGTGAATAAGAAAGTAGGATGGAGCTTTCTAGAGGTTGGGCCTTAGTTCTGTTATCCTCATTGCTTTTAACCAATAAGTTA AATGAAGTTAGAGTTATGGTCTTCAGGTTAGATTATGGACCAGATCTGTGAGGGTCAGCATGGAAATTCACATTCAACAAGGTAGCACAC AGGACCAAGAGCAGCACATGCAATCAACTGGAATAATATAGTAATCCTGTAACTGGGTTTGAAAAAATAATCAACAAAAGATACAATTCA AGGGTTAGGTTGCAGAGAGCTGGCTTGAGAGTAGTTATTATGAAAAAGGCCTCAAGGAGTACGTGTTCAGTATGCTCTAAGATGATAAAG TGGCTGTTAAAAAGGGAGTTGATTTGAGGAAGTATTACTTAGCATTCATGCATATTGGGCTTAGGCTCTAGCCCTGCCACTATCATTGTC TTCTCTGGACTGTGAAGTCACTGAGGACAAGGAAACTAAATTTAATGTCTGTATCACTAGTGCCTAGAATTTCTGGACACTTAGTAGTCA CCATCAGGCGTTTATTTAATGAATGAGAAGCAAAGTGACCTTGGTTACTTTTTTACCCTGAGGGGCTCAGCACTCATTAGGACTTGGTGC CTAATTTTATAAAAAGTCACTAAGCTCAAGTGCTTGGATGAAAGGACAGCGTGGATAAAAAGGTTTTTAAAACATGGATGTTAAGGCTGT TTTGCTTGGAGAAGACTTGGGACTGGGACAGTCTTTAGATATTATTTGAAATGCTGGCACTGTCTATCTGGATCCCAGGGCTTGAACTAG GATTTGAGGAAGTCACAGGGAAGCAGATTTCAGTCTGACATTTATTCAGTGCAAGTTTTTTGGTGCTGTAGTATATGATGAAAGATGTAA AGCTGAATAAAGCATTATTTCTGCCCTAGAGTTGTTCACAGCCTAGTCAGGCATATGGATATGTAAACAATGACTGTAACGTGTTATAGA TGTAAAGACAAAATAAAGGTTAAAGAGGGCATAAAGGAGCACTCAATTGCAGAGATTTGAGGACATTATTTTTATTTTGAGCTTTAAAAA GATGAATAGGTGTTCTCAGGAGGTAGGGATCTGGCTGAGAGGGAATAATCTGAGCAAAGGTATGAAACAGCCTAATGCATTAGAGAAAAA AGTTCTTTTAGTAAGGCATTTGGGGTTGGGGAAGCTAGAAAAAGAAATGGGAGCTGGTCACACAGGGCCTTGTGTGCCAGACTAAGGGGT TTGTAGTATATATTGTAGGCAGAAGAGATCCATCAACAGATTGCAAGCAAGGAAGTATGTTCACTTTAAAGTTTGAGAAAGAATAGTGTG GAAGCACGTCTCAAATTTAGACTTGTTCCCCCTCTGAACCGTGAATCAGACCATTTCAGGTAGAAGTCTTCCCCGGTTTATCTGATCTAC TCGGGGCCTCAGGCTTCTCAGCTGGGAAGAGAGGATGCAAGACCAGACTGAAGAACACGGTTGAGTCCCCAGAACCAAAAGGGGGCCTTT CTGCTTCTTAGCCAGCTACCTCTTCGAGTTTTTCAAATTGTGAGGGGGACCATAAAAGGATGGAAACTTTTAGATGACATTCTACAAATT ATTTTTTTCTTTAAATTAAAAGAACCTAGCCAATAAGATAGAGAATGGGCATCTAAGGCATCTCAGAGCTCTCTGATGAAGCCAGGTTGT CAAAGATCATTTGCAAAAGAAGGGAAAACTGGCATGACAAAAGCTACAGAGAGGAGAGTGAAATATAGAAGTGTTTGAAATGTTCAAGCT CACAATAAGCTTAAATTTATAGAAAATGCTAAGGTTGTCAAGAAGGCTTTTTTTTTTTTCTTTTTTAAACCTGAGGGCAAAAAGGAATGG ATAAAGTAGTGTAATGGATTGACAATCAGGAAGAACAGAATAACTCAGTTTTTTTTCTCCTACAAGGAGATATGGCTGGACCAAAATAAA |
Top |
FusionGenePPI for EGFR_ERP44 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| EGFR | DCN, SHC1, SH3BGRL, STAT5A, PTPN11, CRK, CSK, CBLB, GRB2, STAT3, CTNNB1, CTNND1, JUP, AR, EGFR, CAMLG, PRKCA, HBEGF, TJP1, ATP5C1, SGSM2, WAS, EGF, INPPL1, DUSP3, AREG, PTK2, CBL, CBLC, CDH1, MAPK14, VAV1, VAV2, VAV3, STAT1, SRC, JAK2, HTT, PTK6, PTK2B, DOK2, SOS1, SOS2, CDC25A, NCK1, IGF1R, PRKAR1A, PRKACA, PLD2, ARF4, MAP4K1, NCK2, EPS15, PTPN6, SH2D3A, PLSCR1, GRB14, RASA1, GRB10, PTPN1, NRG1, CD44, PLCG1, SH3KBP1, PIK3C2B, SOCS1, SOCS3, CAV1, CAV3, ERBB3, CD82, SNX6, SNX1, SNX2, SNX4, STAT5B, RGS16, CEBPB, MUC1, GAB1, RIPK1, MAP3K14, PDGFRB, SHC3, CASP1, EREG, FER, ERBB2, HGS, NCAM1, HDAC6, AIP, PSMA7, MEGF6, SORBS2, HEXIM1, AHSA1, ALDOA, UROD, UCHL1, HSP90B1, CBR1, FAH, GOT1, RAB3A, CSRP1, CFL1, EEF1G, PRKAR1B, ATIC, STIP1, HSPA4, MDH1, PTGDS, MATR3, SEPP1, OAZ1, PSMD4, TPI1, GABARAPL2, ARF6, CNTN2, FKBP4, AKAP12, PTPN12, PRDX1, AHNAK, MAP3K12, GPM6B, DCTN2, COL9A3, DYNC1H1, FKBP8, SPCS2, PDK3, UBE2V2, ADRM1, RAP1GDS1, HSPA8, PPP5C, HSPA1A, FN1, TPM1, KCTD9P2, TMCO3, CEND1, RUSC2, SPARCL1, MGARP, PRCC, AP2M1, NDN, OLFM1, DNAJC4, VAPA, STUB1, PIN4, MAST1, MOB4, CCDC50, USP8, PCNA, EPN1, PDCD6IP, SH3GL2, LRIG1, UBASH3A, UBASH3B, HSP90AA1, TNK2, NDFIP1, NDFIP2, LGALS1, LGALS3, NEDD4, ZFYVE28, UBC, PIK3R2, SNRPD2, ACTA2, PIK3R1, ERRFI1, MTCO2P1, YWHAZ, SMURF2, OTUD7B, CALM1, USP2, YAP1, ATXN2, CD2AP, PRKCB, H2AFX, PPP2R3A, RABGEF1, PTPRJ, SOCS4, EPS8, STAM2, RIN1, SEC61B, EMD, TOM1L1, RBM10, TRAF2, HNRNPH1, BCLAF1, C11orf84, DOCK4, MYCBP, CRKL, TAB1, RIOK1, JAK1, CDK1, DDX60, ODF3L2, HCFC1, IRS2, RBM41, PICALM, MPV17, CALU, TRPV1, ESR1, ERBB4, HSP90AB1, HSPA5, CDC37, CTGF, RNF115, RNF126, APBB1, IRS4, SH2D1A, APBB3, APBA3, ABL1, FES, PLCG2, IRS1, ABL2, ZAP70, SYK, NUMB, BLK, BMX, SHC2, SLA, MAPK8IP2, DOK6, ANKS1B, CLNK, TNS4, DOK4, RIN2, PIK3R3, ANKS1A, APBB2, SH2D2A, SH2B1, CISH, DOK5, APPL1, MAPK8IP1, SH2B3, TLN1, NUMBL, ANKRD13A, ANKRD13B, ANKRD13D, MAP1LC3A, PTPN23, CHMP4A, DNAJA3, FBXO25, IGKC, IGHG1, TUBB, TUBA4A, TUBB4B, TUBB4A, TUBB2A, TUBB3, IGHG3, TUBB6, HBA1, CSE1L, EEF1A1, KRT86, AP1S1, IPO9, ATXN10, KPNB1, SNRPD1, HSPA2, XPO1, KIAA1524, AP1M2, IPO7, XPOT, PTRF, TNPO1, IPO5, PPP2R1A, DNAJA1, BAG2, HSD17B12, SGPL1, EXOC7, XPO4, PPP2R2A, GCN1L1, EIF2B2, PHGDH, FBXO6, LANCL2, SAAL1, SPTLC1, GEMIN6, DNAJA2, HOOK2, RANBP1, PEX19, ARL1, PPP6C, TNPO3, AP1G2, AP2A1, PPP2R1B, TNPO2, PPP2R5E, AP2B1, RPN1, LTN1, THADA, SEC61A1, EXOC5, TRAPPC3, PDIA3, COG7, IQGAP3, PIK3CB, GAPDH, MMS19, STRAP, MON2, EIF2B3, DARS, DFNA5, EXOC4, COG5, BZW2, DNAAF5, RCN2, COG6, THEM6, SLC39A11, COG4, PFKP, TECR, BUB3, TIMM50, AP1M1, ATP6V1H, OS9, XPO7, DNAJB12, P4HB, IPO4, PPP6R1, SEL1L, USP9X, EPRS, NCDN, EXOC8, PFKL, XPO5, TTC27, AP2A2, ITIH2, PRKDC, PHLDA1, HEATR3, DDX20, IPO11, LGALS8, PSMD2, IPO13, TPP1, EXOC6B, MARS, TBRG4, ZW10, ARHGEF5, AP1G1, IPO8, FDPS, COG1, ATP2A2, NUP85, XPO6, GEMIN4, ALDH3A2, NUP93, RANGAP1, ARFGEF1, EXOC6, ARMC8, TELO2, EIF2B5, PPARGC1A, IARS, EXOC3, NLRP10, KIAA1244, MTOR, DOPEY2, NCAPG2, TTI1, GBF1, SMC2, RNF213, ATR, NBEAL2, FDFT1, RARS, ACOT9, TOR4A, PLAA, TTI2, WDR26, NCAPH2, VAC14, CD59, BIRC3, BIRC2, RQCD1, CAV2, CLTA, CLTCL1, HOXC10, LYN, S100A7, S100A9, SEC13, SFN, SLC3A2, ATP1A1, ATP1B1, ALCAM, ICAM1, TUBA1A, RPA3, RPA2, RPA1, PANK4, HUWE1, OXSR1, PRKAG1, RPS6KA3, PLK1, PFKFB3, EPHA2, DNM1L, UBA2, MAP2K2, HK2, MAP2K4, AP3D1, DNM2, UBR4, RIOK2, SLC12A2, MAP2K3, HK1, ATP5L, PTPRF, ARHGAP1, ITCH, PDK1, TBK1, PLD3, STK26, PPP2R5C, UBE2G2, AP3M1, YES1, PFKM, PRKAA1, AP1S2, AP1B1, CSNK1A1, ACP1, CSNK2A1, AP2S1, CDK5, EIF2AK2, UCK2, UBE2S, AP3S1, VRK1, AKT2, SOCS5, DERL1, PML, DCBLD2, LRSAM1, DSG2, SSBP1, MYO1B, NGLY1, CANX, DPM1, DNAJB11, HSD17B10, DYNC1LI1, FAF2, YARS, IDH2, KIAA0368, SULT1A1, TFRC, CLPX, SRPR, VARS, LRRC40, MRTO4, EIF3M, TRMT10C, TIMM23, SSR4, EHD4, RPRD1A, MYO1D, FBL, HADHB, AFG3L2, CCDC47, SMC1A, SMC3, NDUFA9, UMPS, ITPA, SLFN11, CLPP, CPVL, TM9SF3, LONP1, RPL38, SNRPA1, COPA, APRT, NSF, NSUN5, ATAD1, AIFM1, POLDIP2, WDR6, SCFD1, NDUFS1, OAT, SAMHD1, MGST1, NDUFS3, SNRPF, CNP, ACADSB, ORC5, EIF2B4, PUS1, SDF2L1, IMMT, TARS, DDX47, ACTR2, EIF2B1, HLA-A, VPS4B, EHD1, PYCR2, MYO1C, CUL4B, DHRS7B, RFC5, OSBP, YBEY, EEF1B2, GCLM, GSTK1, TTC37, AK4, CARS2, MINOS1, PELO, MRPL10, FAR1, CTBP1, ABCF2, MPC2, LIMA1, ILVBL, NCAPG, TARS2, COX2, PNO1, IFIT5, EIF3K, CHCHD3, PUM1, TOR1AIP1, GNAS, EIF3F, CMSS1, RPS15A, TMEM97, ETF1, NCAPH, RFC3, TOMM22, STT3A, TUBGCP2, ASNS, HELLS, LARP4, PON2, ABCD3, CDIPT, SDF2, DIMT1, BCCIP, PTGES3, PC, SRPRB, SCAMP3, NAA10, UTP15, GNB2, TRMT2A, ADCK3, CTTN, RER1, IDH3B, LRWD1, C6orf120, BZW1, SLC1A5, TRMT1L, NSUN2, SFXN3, UFL1, SUGP2, IKBKAP, PDS5A, TNFRSF10B, ACACA, HYOU1, ATP5F1, FLOT2, NTPCR, CERS2, SCD, UQCRC2, ATP2B1, EIF4G2, SAMM50, NUBP2, DNAJC11, NCLN, SKIV2L, DIS3, LSR, ATXN7L3B, EMC3, CALR, PRIM1, RNMTL1, AAMP, ATAD3B, RAB18, RPL23, PRMT3, PDXDC1, AAAS, SUCLA2, CTBP2, KIF1A, TRAPPC5, ARMC6, SLC25A13, TBL3, CLU, ARHGEF2, ATP5A1, RPL22, FAM98A, IDH3A, DHCR24, FADS2, CKAP2, FARSA, CEBPZ, ADAR, NUP153, LRPPRC, OPA1, STOM, RFC4, TUBG1, LANCL1, TAF4, PSPC1, EWSR1, AAMDC, GRN, PSMD1, FN3KRP, TPM3, THOP1, CAP2, RPL4, BLM, PLS3, TPM4, NT5DC2, XRCC5, H1FX, MRPL9, LAT, PDGFRA, TNFRSF1A, IKBKG, SNCA, YWHAQ, YWHAB, PRKCE, MAPT, SHC4, DOK1, RAF1, BAIAP2, FGR, ACTN4, AKT1, HCK, RAPGEF1, SH3GL3, MAPK8, NR3C1, PTPN22, FRK, STAP2, ARRB1, LCP2, ITGB2, TGFA, ARRB2, PRKCZ, HDAC7, RET, SH2D3C, SLA2, CDH5, ITK, CDC25C, ITSN2, MAP3K3, PIM1, GRAP2, S100A4, SNX9, NTRK2, PTPN18, PAK1, MAPK9, WASL, TNS3, WASF3, ARHGEF7, SOCS6, APP, LRP1, STAT2, TLR2, RGS4, TMEM25, PTCH1, PTPRK, AKTIP, NTRK1, PIGS, TP53, ARHGAP32, PARK2, CTNNA1, FOS, HSPA1B, EZR, TXN, PPARG, KEAP1, NELL1, SUSD1, CSTA, HSPA9, ANO5, ANXA1, COL17A1, CTNNA2, HIST1H2AA, HSPB1, RPS15, RBM25, RPS26P11, SPRR1A, SERPINB4, SERAC1, SFPQ, PTPRD, MET, ITGB4, XRN2, GSTT1, DBR1, SLC7A5, VPS13A, YTHDF1, RPL17, ATP2B4, APOB, ESRRB, OSMR, HBA2, ACTB, MYH9, IQGAP1, PTPRU, PTPRB, FAM129B, LRIG2, KRAS, BBC3, GSTP1, L1CAM, RRAD, MIF, HIP1, ERCC1, ERCC4, CLCN5, MCM4, APEX1, NCL, NPM1, PARP1, LMNA, FUS, ERCC2, TRIM28, MCM3, MCM6, FEN1, ILF2, ILF3, DHX9, BRE, TOP1, BRAF, LTK, IGFBP2, CDH2, ITGB1, CCDC88A, PDP1, PTPRR, PTPN7, PTPRA, PTPRH, PTPRT, PPM1A, PPM1F, DUSP14, DUSP18, MPZL2, SSH1, FAM186A, SRRM4, CD300LB, SMTNL1, KRTAP16-1, MYO9A, BTBD18, IGLL5, RASA4B, PGRMC1, SUPT5H, ACACB, TRAFD1, EIF1AY, SEC16A, ZBTB22, PMM2, EPB41L2, FOXO3, HTATSF1, DYRK3, ZBTB14, DHX16, CEP104, EIF5B, NPHP4, DNAJC13, SPAG7, TOMM70A, SLITRK3, OR2F2, LUC7L3, LCA5L, ABCA1, HERC2, PAK4, DHFR, HLA-B, COL1A1, AHSG, MAS1, KRT1, HMGN2, RPLP2, SSB, CTSD, COL1A2, KRT16, HMGB1, FAM66E, ZCCHC18, CKMT1A, DRD2, GLUL, HMGA1, DDX5, TCP1, RPL7, CD58, NF1, IGHV1-2, PPIB, RPS3, EIF4B, TNC, PSMA3, PSMA4, U2AF2, CNTF, HMGB2, DPP4, MAP4, HSD11B1, POLR2A, GABRA3, KRT9, TRIM23, RPL3, RPS27, GRIK4, TUFM, ALDH7A1, RPL14, IDH3G, IRAK1, KCNQ1, HDGF, BTAF1, SUB1, MFAP1, EIF3B, SESN2, KRTAP10-9, RPS20, S100A10, HNRNPK, CNBP, RAB1A, TRA2B, YBX1, NTHL1, XIAP, SRSF2, AKAP17A, RPL6, SRSF11, SLC3A1, SSRP1, RASGEF1B, MIR22HG, C5orf28, BPTF, CSTF3, G3BP1, TCOF1, PDAP1, TCIRG1, HDAC1, CDK13, CIRBP, LRP8, PDE1C, UBAP2L, CAPRIN1, RBM39, DIP2A, CBX2, GRM4, STIL, DIXDC1, HERC1, E2F4, MICB, MRGPRG-AS1, P3H1, LRRK1, KRTAP15-1, PTPN20B, AASDH, ARHGAP29, FBLN7, SLC45A4, PAGE3, DOPEY1, CEP170, EYS, SWT1, KIAA1217, ATF7IP2, ZMYM4, CES4A, WWC2, HIST2H2AA3, NADSYN1, PLEKHA7, ADAM5, MAST2, ARMCX5, XRRA1, SCYL2, GIGYF2, EML6, LOC400499, USP34, USP31, CYS1, SMIM5, RSRC2, ZC3HAV1, PID1, SETX, OR2W3, PRSS42, NEK8, LRRTM4, HEATR4, ZNF573, SLC13A5, HRNR, CCDC60, FAM126B, SRRM1, CCDC146, ZZZ3, CENPL, MIER1, UNC80, EFCAB3, TRIML2, C2orf61, MRPL43, TOPAZ1, ZNF114, SERBP1, LSM14A, CTCFL, BBS10, MAPK15, CHD6, TRAF3IP1, HEXDC, LMBR1, KBTBD7, MUC16, DNAH7, TTN, ROBO4, SLC39A7, EDEM1, ZNF516, DHX38, DAZL, TMBIM1, TMEM159, DOCK10, MTBP, ELP4, MTMR8, RNF125, DNAH8, SCYL1, ZFR, PRICKLE1, RUNDC3B, SERPINB12, SMG1, PCNX, SPEN, TSG101, SPAG8, NABP2, ZFYVE21, SYT17, CNPY3, MTG1, C2orf49, PRR14, PLVAP, API5, NXF2, KATNBL1, SPATC1L, NUCKS1, RWDD1, DPEP3, REEP4, NOL6, RPF1, SNX29, TRPM3, IL1RAPL2, MLXIPL, INCENP, EXOSC3, SERTAD4, RLIM, GPATCH2, RCC2, HECW2, CRCT1, TMEM2, TEKT2, SLCO3A1, HN1, TNIK, GPATCH8, TRHDE, BAG5, GRID1, SLC45A2, MAGED2, ING4, ZC3H4, AGTPBP1, SHANK2, SRRM2, RUVBL2, COA3, NOSIP, CBY1, WIPI2, PCDHGA3, KRT3, KRT10, KRT2, KRT5, GOLGB1, GPR149, NF2, CTDSPL, SCGB1D4, DEFA1, ST8SIA4, HTR3A, PCDHB11, RAB31, PPP3CB, PPM1B, ILKAP, DUSP19, STYX, WBP2, PTEN, LINC01139, GPNMB, RGS2, PTPN2, HPN, UBE2J2 | ERP44 | CD40, ERO1L, ERO1LB, USP46, USP32, UIMC1, RASSF5, ELAVL1, CKB, CNN2, FERMT2, G6PD, FHL2, ISOC1, LARS, NUDCD1, OSGEP, PAK2, PDCD10, PFAS, PLD3, TBCB, UBFD1, VCL, YWHAZ, FUS, CUL7, YAP1, PNPO, SNX2, NTRK1, ALDH7A1, NRD1, PIAS1, FAM13A, PACSIN2, ID1, EPB41L4B, KMT2C, COPS7B, TMEM189, MCM2, MCM5, IL12B, CDC73, DUSP8, ZFPM1, MEX3A, STXBP4, PXDN, FAM73A, TGFB1, DCP1B, ZNF212, DAPK1, BCOR, ZNF777, ZMYM1, TNIP1, ITPKC, GNL3L, RPIA, RBBP8, UBE2Q1, HOXA5, POLD2, SUMF1, FIGN, FN1, CASP3, BTD, PRIM2, PTPRN, PTPRO, EDEM3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | ERP44 | chr7:55087058 | chr9:102784508 | ENST00000262455 | - | 3 | 12 | 236_285 | 95 | 407 | ITPR1 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for EGFR_ERP44 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | EGFR | P00533 | DB00002 | Cetuximab | Epidermal growth factor receptor | biotech | approved |
| Hgene | EGFR | P00533 | DB05294 | Vandetanib | Epidermal growth factor receptor | small molecule | approved |
| Hgene | EGFR | P00533 | DB08916 | Afatinib | Epidermal growth factor receptor | small molecule | approved |
| Hgene | EGFR | P00533 | DB00072 | Trastuzumab | Epidermal growth factor receptor | biotech | approved|investigational |
| Hgene | EGFR | P00533 | DB00317 | Gefitinib | Epidermal growth factor receptor | small molecule | approved|investigational |
| Hgene | EGFR | P00533 | DB00530 | Erlotinib | Epidermal growth factor receptor | small molecule | approved|investigational |
| Hgene | EGFR | P00533 | DB01259 | Lapatinib | Epidermal growth factor receptor | small molecule | approved|investigational |
| Hgene | EGFR | P00533 | DB01269 | Panitumumab | Epidermal growth factor receptor | biotech | approved|investigational |
| Hgene | EGFR | P00533 | DB09559 | Necitumumab | Epidermal growth factor receptor | biotech | approved|investigational |
| Hgene | EGFR | P00533 | DB00281 | Lidocaine | Epidermal growth factor receptor | small molecule | approved|vet_approved |
Top |
RelatedDiseases for EGFR_ERP44 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | EGFR | C0007131 | Non-Small Cell Lung Carcinoma | 16 | CTD_human |
| Hgene | EGFR | C1458155 | Mammary Neoplasms | 6 | CTD_human |
| Hgene | EGFR | C0024121 | Lung Neoplasms | 5 | CTD_human |
| Hgene | EGFR | C0001418 | Adenocarcinoma | 4 | CTD_human |
| Hgene | EGFR | C0007137 | Squamous cell carcinoma | 3 | CTD_human |
| Hgene | EGFR | C0007873 | Uterine Cervical Neoplasm | 3 | CTD_human |
| Hgene | EGFR | C0014859 | Esophageal Neoplasms | 3 | CTD_human |
| Hgene | EGFR | C0017636 | Glioblastoma | 3 | CTD_human |
| Hgene | EGFR | C0018671 | Head and Neck Neoplasms | 3 | CTD_human |
| Hgene | EGFR | C0027627 | Neoplasm Metastasis | 3 | CTD_human |
| Hgene | EGFR | C0033578 | Prostatic Neoplasms | 3 | CTD_human |
| Hgene | EGFR | C0038356 | Stomach Neoplasms | 3 | CTD_human |
| Hgene | EGFR | C0005695 | Bladder Neoplasm | 2 | CTD_human |
| Hgene | EGFR | C0009375 | Colonic Neoplasms | 2 | CTD_human |
| Hgene | EGFR | C0009404 | Colorectal Neoplasms | 2 | CTD_human |
| Hgene | EGFR | C0024668 | Mammary Neoplasms, Experimental | 2 | CTD_human |
| Hgene | EGFR | C0027626 | Neoplasm Invasiveness | 2 | CTD_human |
| Hgene | EGFR | C0027643 | Neoplasm Recurrence, Local | 2 | CTD_human |
| Hgene | EGFR | C0152013 | Adenocarcinoma of lung (disorder) | 2 | CTD_human |
| Hgene | EGFR | C0919267 | ovarian neoplasm | 2 | CTD_human |
| Hgene | EGFR | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
| Hgene | EGFR | C0005396 | Bile Duct Neoplasms | 1 | CTD_human |
| Hgene | EGFR | C0007193 | Cardiomyopathy, Dilated | 1 | CTD_human |
| Hgene | EGFR | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 1 | CTD_human |
| Hgene | EGFR | C0014175 | Endometriosis | 1 | CTD_human |
| Hgene | EGFR | C0016978 | gallbladder neoplasm | 1 | CTD_human |
| Hgene | EGFR | C0021655 | Insulin Resistance | 1 | CTD_human |
| Hgene | EGFR | C0024667 | Animal Mammary Neoplasms | 1 | CTD_human |
| Hgene | EGFR | C0024809 | Marijuana Abuse | 1 | PSYGENET |
| Hgene | EGFR | C0025500 | Mesothelioma | 1 | CTD_human |
| Hgene | EGFR | C0027439 | Nasopharyngeal Neoplasms | 1 | CTD_human |
| Hgene | EGFR | C0029463 | Osteosarcoma | 1 | CTD_human |
| Hgene | EGFR | C0030354 | Papilloma | 1 | CTD_human |
| Hgene | EGFR | C0032580 | Adenomatous Polyposis Coli | 1 | CTD_human |
| Hgene | EGFR | C0034885 | Rectal Neoplasms | 1 | CTD_human |
| Hgene | EGFR | C0041696 | Unipolar Depression | 1 | PSYGENET |
| Hgene | EGFR | C0085548 | Autosomal Recessive Polycystic Kidney Disease | 1 | CTD_human |
| Hgene | EGFR | C0085762 | Alcohol abuse | 1 | PSYGENET |
| Hgene | EGFR | C0149925 | Small cell carcinoma of lung | 1 | CTD_human |
| Hgene | EGFR | C0206686 | Adrenocortical carcinoma | 1 | CTD_human |
| Hgene | EGFR | C0206698 | Cholangiocarcinoma | 1 | CTD_human |
| Hgene | EGFR | C0263454 | Chloracne | 1 | CTD_human |
| Hgene | EGFR | C0279626 | Squamous cell carcinoma of esophagus | 1 | CTD_human |
| Hgene | EGFR | C0345967 | Malignant mesothelioma | 1 | CTD_human |
| Hgene | EGFR | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| Hgene | EGFR | C0993582 | Arthritis, Experimental | 1 | CTD_human |
| Hgene | EGFR | C1269683 | Major Depressive Disorder | 1 | PSYGENET |
| Hgene | EGFR | C2239176 | Liver carcinoma | 1 | CTD_human |
| Hgene | EGFR | C2609414 | Acute kidney injury | 1 | CTD_human |
| Hgene | EGFR | C4015130 | INFLAMMATORY SKIN AND BOWEL DISEASE, NEONATAL, 2 | 1 | UNIPROT |
| Tgene | ERP44 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
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