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Fusion gene ID: 11026 |
FusionGeneSummary for EFCAB14_EFCAB14 |
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Fusion gene information | Fusion gene name: EFCAB14_EFCAB14 | Fusion gene ID: 11026 | Hgene | Tgene | Gene symbol | EFCAB14 | EFCAB14 | Gene ID | 9813 | 9813 |
Gene name | EF-hand calcium binding domain 14 | EF-hand calcium binding domain 14 | |
Synonyms | KIAA0494 | KIAA0494 | |
Cytomap | 1p33 | 1p33 | |
Type of gene | protein-coding | protein-coding | |
Description | EF-hand calcium-binding domain-containing protein 14 | EF-hand calcium-binding domain-containing protein 14 | |
Modification date | 20180522 | 20180522 | |
UniProtAcc | O75071 | O75071 | |
Ensembl transtripts involved in fusion gene | ENST00000544071, ENST00000371933, ENST00000484461, | ENST00000544071, ENST00000371933, ENST00000484461, | |
Fusion gene scores | * DoF score | 1 X 2 X 1=2 | 5 X 5 X 2=50 |
# samples | 2 | 5 | |
** MAII score | log2(2/2*10)=3.32192809488736 | log2(5/50*10)=0 | |
Context | PubMed: EFCAB14 [Title/Abstract] AND EFCAB14 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AA252565 | EFCAB14 | chr1 | 47142118 | + | EFCAB14 | chr1 | 47142091 | - | ||
ChiTaRS3.1 | CB242814 | EFCAB14 | chr1 | 47140961 | + | EFCAB14 | chr1 | 47141209 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000544071 | ENST00000544071 | EFCAB14 | chr1 | 47142118 | + | EFCAB14 | chr1 | 47142091 | - |
intron-3UTR | ENST00000544071 | ENST00000371933 | EFCAB14 | chr1 | 47142118 | + | EFCAB14 | chr1 | 47142091 | - |
intron-intron | ENST00000544071 | ENST00000484461 | EFCAB14 | chr1 | 47142118 | + | EFCAB14 | chr1 | 47142091 | - |
intron-intron | ENST00000371933 | ENST00000544071 | EFCAB14 | chr1 | 47142118 | + | EFCAB14 | chr1 | 47142091 | - |
intron-3UTR | ENST00000371933 | ENST00000371933 | EFCAB14 | chr1 | 47142118 | + | EFCAB14 | chr1 | 47142091 | - |
intron-intron | ENST00000371933 | ENST00000484461 | EFCAB14 | chr1 | 47142118 | + | EFCAB14 | chr1 | 47142091 | - |
intron-intron | ENST00000484461 | ENST00000544071 | EFCAB14 | chr1 | 47142118 | + | EFCAB14 | chr1 | 47142091 | - |
intron-3UTR | ENST00000484461 | ENST00000371933 | EFCAB14 | chr1 | 47142118 | + | EFCAB14 | chr1 | 47142091 | - |
intron-intron | ENST00000484461 | ENST00000484461 | EFCAB14 | chr1 | 47142118 | + | EFCAB14 | chr1 | 47142091 | - |
intron-intron | ENST00000544071 | ENST00000544071 | EFCAB14 | chr1 | 47140961 | + | EFCAB14 | chr1 | 47141209 | - |
intron-3UTR | ENST00000544071 | ENST00000371933 | EFCAB14 | chr1 | 47140961 | + | EFCAB14 | chr1 | 47141209 | - |
intron-intron | ENST00000544071 | ENST00000484461 | EFCAB14 | chr1 | 47140961 | + | EFCAB14 | chr1 | 47141209 | - |
intron-intron | ENST00000371933 | ENST00000544071 | EFCAB14 | chr1 | 47140961 | + | EFCAB14 | chr1 | 47141209 | - |
intron-3UTR | ENST00000371933 | ENST00000371933 | EFCAB14 | chr1 | 47140961 | + | EFCAB14 | chr1 | 47141209 | - |
intron-intron | ENST00000371933 | ENST00000484461 | EFCAB14 | chr1 | 47140961 | + | EFCAB14 | chr1 | 47141209 | - |
intron-intron | ENST00000484461 | ENST00000544071 | EFCAB14 | chr1 | 47140961 | + | EFCAB14 | chr1 | 47141209 | - |
intron-3UTR | ENST00000484461 | ENST00000371933 | EFCAB14 | chr1 | 47140961 | + | EFCAB14 | chr1 | 47141209 | - |
intron-intron | ENST00000484461 | ENST00000484461 | EFCAB14 | chr1 | 47140961 | + | EFCAB14 | chr1 | 47141209 | - |
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FusionProtFeatures for EFCAB14_EFCAB14 |
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Hgene | Tgene |
EFCAB14 | EFCAB14 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for EFCAB14_EFCAB14 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for EFCAB14_EFCAB14 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for EFCAB14_EFCAB14 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for EFCAB14_EFCAB14 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |