![]() |
||||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Fusion gene ID: 10977 |
FusionGeneSummary for EEF1G_EEF1G |
![]() |
Fusion gene information | Fusion gene name: EEF1G_EEF1G | Fusion gene ID: 10977 | Hgene | Tgene | Gene symbol | EEF1G | EEF1G | Gene ID | 1937 | 1937 |
Gene name | eukaryotic translation elongation factor 1 gamma | eukaryotic translation elongation factor 1 gamma | |
Synonyms | EF1G|GIG35 | EF1G|GIG35 | |
Cytomap | 11q12.3 | 11q12.3 | |
Type of gene | protein-coding | protein-coding | |
Description | elongation factor 1-gammaEF-1-gammaPRO1608eEF-1B gammapancreatic tumor-related proteintranslation elongation factor eEF-1 gamma chain | elongation factor 1-gammaEF-1-gammaPRO1608eEF-1B gammapancreatic tumor-related proteintranslation elongation factor eEF-1 gamma chain | |
Modification date | 20180523 | 20180523 | |
UniProtAcc | P26641 | P26641 | |
Ensembl transtripts involved in fusion gene | ENST00000329251, ENST00000378019, ENST00000532986, | ENST00000329251, ENST00000378019, ENST00000532986, | |
Fusion gene scores | * DoF score | 4 X 3 X 3=36 | 3 X 4 X 4=48 |
# samples | 4 | 4 | |
** MAII score | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: EEF1G [Title/Abstract] AND EEF1G [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
![]() |
Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BI046948 | EEF1G | chr11 | 62334929 | - | EEF1G | chr11 | 62339115 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3CDS | ENST00000329251 | ENST00000329251 | EEF1G | chr11 | 62334929 | - | EEF1G | chr11 | 62339115 | - |
intron-3CDS | ENST00000329251 | ENST00000378019 | EEF1G | chr11 | 62334929 | - | EEF1G | chr11 | 62339115 | - |
intron-5UTR | ENST00000329251 | ENST00000532986 | EEF1G | chr11 | 62334929 | - | EEF1G | chr11 | 62339115 | - |
intron-3CDS | ENST00000378019 | ENST00000329251 | EEF1G | chr11 | 62334929 | - | EEF1G | chr11 | 62339115 | - |
intron-3CDS | ENST00000378019 | ENST00000378019 | EEF1G | chr11 | 62334929 | - | EEF1G | chr11 | 62339115 | - |
intron-5UTR | ENST00000378019 | ENST00000532986 | EEF1G | chr11 | 62334929 | - | EEF1G | chr11 | 62339115 | - |
intron-3CDS | ENST00000532986 | ENST00000329251 | EEF1G | chr11 | 62334929 | - | EEF1G | chr11 | 62339115 | - |
intron-3CDS | ENST00000532986 | ENST00000378019 | EEF1G | chr11 | 62334929 | - | EEF1G | chr11 | 62339115 | - |
intron-5UTR | ENST00000532986 | ENST00000532986 | EEF1G | chr11 | 62334929 | - | EEF1G | chr11 | 62339115 | - |
Top |
FusionProtFeatures for EEF1G_EEF1G |
![]() |
Hgene | Tgene |
EEF1G | EEF1G |
Probably plays a role in anchoring the complex to othercellular components. | Probably plays a role in anchoring the complex to othercellular components. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for EEF1G_EEF1G |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
Top |
FusionGenePPI for EEF1G_EEF1G |
![]() |
![]() |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for EEF1G_EEF1G |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for EEF1G_EEF1G |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |