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Fusion gene ID: 10902 |
FusionGeneSummary for ECHDC3_ECHDC3 |
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Fusion gene information | Fusion gene name: ECHDC3_ECHDC3 | Fusion gene ID: 10902 | Hgene | Tgene | Gene symbol | ECHDC3 | ECHDC3 | Gene ID | 79746 | 79746 |
Gene name | enoyl-CoA hydratase domain containing 3 | enoyl-CoA hydratase domain containing 3 | |
Synonyms | - | - | |
Cytomap | 10p14 | 10p14 | |
Type of gene | protein-coding | protein-coding | |
Description | enoyl-CoA hydratase domain-containing protein 3, mitochondrialenoyl Coenzyme A hydratase domain containing 3testis tissue sperm-binding protein Li 76m | enoyl-CoA hydratase domain-containing protein 3, mitochondrialenoyl Coenzyme A hydratase domain containing 3testis tissue sperm-binding protein Li 76m | |
Modification date | 20180522 | 20180522 | |
UniProtAcc | Q96DC8 | Q96DC8 | |
Ensembl transtripts involved in fusion gene | ENST00000496136, ENST00000379215, | ENST00000496136, ENST00000379215, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 3 X 2 X 3=18 |
# samples | 1 | 3 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: ECHDC3 [Title/Abstract] AND ECHDC3 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BI254560 | ECHDC3 | chr10 | 11805882 | - | ECHDC3 | chr10 | 11805925 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
3UTR-3UTR | ENST00000496136 | ENST00000496136 | ECHDC3 | chr10 | 11805882 | - | ECHDC3 | chr10 | 11805925 | + |
3UTR-3UTR | ENST00000496136 | ENST00000379215 | ECHDC3 | chr10 | 11805882 | - | ECHDC3 | chr10 | 11805925 | + |
3UTR-3UTR | ENST00000379215 | ENST00000496136 | ECHDC3 | chr10 | 11805882 | - | ECHDC3 | chr10 | 11805925 | + |
3UTR-3UTR | ENST00000379215 | ENST00000379215 | ECHDC3 | chr10 | 11805882 | - | ECHDC3 | chr10 | 11805925 | + |
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FusionProtFeatures for ECHDC3_ECHDC3 |
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Hgene | Tgene |
ECHDC3 | ECHDC3 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ECHDC3_ECHDC3 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for ECHDC3_ECHDC3 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ECHDC3_ECHDC3 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ECHDC3_ECHDC3 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |