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Fusion gene ID: 1060 |
FusionGeneSummary for AGAP1_RINT1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AGAP1_RINT1 | Fusion gene ID: 1060 | Hgene | Tgene | Gene symbol | AGAP1 | RINT1 | Gene ID | 116987 | 60561 |
| Gene name | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | RAD50 interactor 1 | |
| Synonyms | AGAP-1|CENTG2|GGAP1|cnt-g2 | RINT-1 | |
| Cytomap | 2q37.2 | 7q22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1GTP-binding and GTPase-activating protein 1centaurin, gamma 2 | RAD50-interacting protein 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9UPQ3 | Q6NUQ1 | |
| Ensembl transtripts involved in fusion gene | ENST00000336665, ENST00000304032, ENST00000409538, ENST00000428334, ENST00000409457, | ENST00000257700, ENST00000477285, | |
| Fusion gene scores | * DoF score | 25 X 11 X 14=3850 | 4 X 4 X 3=48 |
| # samples | 26 | 4 | |
| ** MAII score | log2(26/3850*10)=-3.88827491744117 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: AGAP1 [Title/Abstract] AND RINT1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A7-A0DA-01A | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000336665 | ENST00000257700 | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
| 5CDS-intron | ENST00000336665 | ENST00000477285 | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
| In-frame | ENST00000304032 | ENST00000257700 | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
| 5CDS-intron | ENST00000304032 | ENST00000477285 | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
| In-frame | ENST00000409538 | ENST00000257700 | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
| 5CDS-intron | ENST00000409538 | ENST00000477285 | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
| In-frame | ENST00000428334 | ENST00000257700 | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
| 5CDS-intron | ENST00000428334 | ENST00000477285 | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
| intron-3CDS | ENST00000409457 | ENST00000257700 | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
| intron-intron | ENST00000409457 | ENST00000477285 | AGAP1 | chr2 | 236792093 | + | RINT1 | chr7 | 105204180 | + |
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FusionProtFeatures for AGAP1_RINT1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AGAP1 | RINT1 |
| GTPase-activating protein for ARF1 and, to a lesserextent, ARF5. Directly and specifically regulates the adapterprotein 3 (AP-3)-dependent trafficking of proteins in theendosomal-lysosomal system. {ECO:0000269|PubMed:12640130}. | Involved in regulation of membrane traffic between theGolgi and the endoplasmic reticulum (ER); the function is proposedto depend on its association in the NRZ complex which is believedto play a role in SNARE assembly at the ER. May play a role incell cycle checkpoint control (PubMed:11096100). Essential fortelomere length control (PubMed:16600870).{ECO:0000269|PubMed:11096100, ECO:0000269|PubMed:16600870,ECO:0000305}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000304032 | + | 10 | 18 | 122_126 | 385 | 858 | Nucleotide binding | GTP |
| Hgene | AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000304032 | + | 10 | 18 | 178_181 | 385 | 858 | Nucleotide binding | GTP |
| Hgene | AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000304032 | + | 10 | 18 | 78_85 | 385 | 858 | Nucleotide binding | GTP |
| Hgene | AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000336665 | + | 10 | 17 | 122_126 | 385 | 805 | Nucleotide binding | GTP |
| Hgene | AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000336665 | + | 10 | 17 | 178_181 | 385 | 805 | Nucleotide binding | GTP |
| Hgene | AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000336665 | + | 10 | 17 | 78_85 | 385 | 805 | Nucleotide binding | GTP |
| Hgene | AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000304032 | + | 10 | 18 | 66_276 | 385 | 858 | Region | Note=Small GTPase-like |
| Hgene | AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000336665 | + | 10 | 17 | 66_276 | 385 | 805 | Region | Note=Small GTPase-like |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000304032 | + | 10 | 18 | 346_588 | 385 | 858 | Domain | PH |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000304032 | + | 10 | 18 | 609_729 | 385 | 858 | Domain | Arf-GAP |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000336665 | + | 10 | 17 | 346_588 | 385 | 805 | Domain | PH |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000336665 | + | 10 | 17 | 609_729 | 385 | 805 | Domain | Arf-GAP |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000409457 | + | 1 | 10 | 346_588 | -200 | 406 | Domain | PH |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000409457 | + | 1 | 10 | 609_729 | -200 | 406 | Domain | Arf-GAP |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000409457 | + | 1 | 10 | 122_126 | -200 | 406 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000409457 | + | 1 | 10 | 178_181 | -200 | 406 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000409457 | + | 1 | 10 | 78_85 | -200 | 406 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000409457 | + | 1 | 10 | 66_276 | -200 | 406 | Region | Note=Small GTPase-like |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000304032 | + | 10 | 18 | 768_797 | 385 | 858 | Repeat | Note=ANK 1 |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000304032 | + | 10 | 18 | 801_830 | 385 | 858 | Repeat | Note=ANK 2 |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000336665 | + | 10 | 17 | 768_797 | 385 | 805 | Repeat | Note=ANK 1 |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000336665 | + | 10 | 17 | 801_830 | 385 | 805 | Repeat | Note=ANK 2 |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000409457 | + | 1 | 10 | 768_797 | -200 | 406 | Repeat | Note=ANK 1 |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000409457 | + | 1 | 10 | 801_830 | -200 | 406 | Repeat | Note=ANK 2 |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000304032 | + | 10 | 18 | 624_647 | 385 | 858 | Zinc finger | C4-type |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000336665 | + | 10 | 17 | 624_647 | 385 | 805 | Zinc finger | C4-type |
| Hgene | >AGAP1 | chr2:236792093 | chr7:105204180 | ENST00000409457 | + | 1 | 10 | 624_647 | -200 | 406 | Zinc finger | C4-type |
| Tgene | RINT1 | chr2:236792093 | chr7:105204180 | ENST00000257700 | + | 10 | 15 | 103_124 | 557 | 793 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | RINT1 | chr2:236792093 | chr7:105204180 | ENST00000257700 | + | 10 | 15 | 220_792 | 557 | 793 | Domain | RINT1/TIP20 |
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FusionGeneSequence for AGAP1_RINT1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_AGAP1_ENST00000336665_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_621aa MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHR YLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSN GGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS LNKEWKKKYVTLCDNGVLTYHPSLHFFLQLQQAALEVFAENNTLSKLQLGQLASMESSVFDDMINLLERLKHDMLTRQVDHVFREVKDAA KLYKKERWLSLPSQSEQAVMSLSSSACPLLLTLRDHLLQLEQQLCFSLFKIFWQMLVEKLDVYIYQEIILANHFNEGGAAQLQFDMTRNL >In-frame_AGAP1_ENST00000304032_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_621aa MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHR YLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSN GGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS LNKEWKKKYVTLCDNGVLTYHPSLHFFLQLQQAALEVFAENNTLSKLQLGQLASMESSVFDDMINLLERLKHDMLTRQVDHVFREVKDAA KLYKKERWLSLPSQSEQAVMSLSSSACPLLLTLRDHLLQLEQQLCFSLFKIFWQMLVEKLDVYIYQEIILANHFNEGGAAQLQFDMTRNL >In-frame_AGAP1_ENST00000409538_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_886aa MYLLDGSGEPASPPADAMPRGTPPRKTVYRISVTMVRKEQLAAPGSGGPDPRPVRRPRPARSPDAPGRLEEEAEEAEGAEEPEGPRPRAW DFRTFRTRSTGQLELGRLRPCARGLEPADLAGSAPAEEEGRGSPASGSPDVEGARAAPLRRSLSFRHWSGPEAPQGRTLGGGRRHSSSGS LAWAPCDEAAAGTTLEPATATQPASEKRNTLDVGEVLSKNDALSDLERWERSKSKNRTLDNSDLQRLERARAAAGAGAASEHRLLRFFSG IFARRDGGPGGGPSPRSGASRPRGYFSLRRAPAEAHSSSAESIDGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGT YVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSA NPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSL SDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEW KKKYVTLCDNGVLTYHPSLHFFLQLQQAALEVFAENNTLSKLQLGQLASMESSVFDDMINLLERLKHDMLTRQVDHVFREVKDAAKLYKK ERWLSLPSQSEQAVMSLSSSACPLLLTLRDHLLQLEQQLCFSLFKIFWQMLVEKLDVYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFS >In-frame_AGAP1_ENST00000428334_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_460aa MANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPS HSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIG SGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHFFLQLQQAALEVFAENNTLSKLQLGQLASMESSVFDDMINLLERLK HDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQSEQAVMSLSSSACPLLLTLRDHLLQLEQQLCFSLFKIFWQMLVEKLDVYIYQEIILA NHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHIKEACIVLNLNVGSALLLKDVLQSASGQLPATAALNEVGIYKLAQQDVEILLNL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_AGAP1_ENST00000336665_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_1863nt ATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATC TACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGC CAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGG TACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTG CTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATA AGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGAT GCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACG TGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATA GGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAAT GGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACT GCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAG AAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCG TTGAATAAAGAGTGGAAAAAGAAATATGTCACCCTGTGTGACAATGGCGTGCTGACCTATCATCCCAGTTTACATTTCTTTCTACAACTT CAACAGGCTGCACTGGAGGTGTTTGCAGAGAATAATACTCTGAGTAAATTGCAGCTAGGACAGCTAGCCTCTATGGAGAGCTCTGTCTTT GATGACATGATTAACCTCTTAGAACGTTTAAAGCATGATATGTTGACCCGTCAAGTAGACCACGTTTTTAGAGAAGTTAAAGATGCTGCA AAATTGTATAAAAAAGAAAGATGGTTGTCCTTGCCATCTCAGTCAGAGCAGGCAGTGATGTCCCTGTCCAGTTCGGCTTGCCCGTTGCTG CTGACGTTACGAGACCATTTACTTCAGTTGGAGCAGCAGCTTTGTTTCTCCTTATTTAAAATTTTCTGGCAAATGCTTGTAGAGAAGCTG GATGTATACATCTACCAAGAAATAATTCTTGCTAATCACTTCAATGAAGGAGGAGCAGCCCAGCTGCAGTTTGATATGACTCGGAATCTT TTCCCTTTGTTTTCTCACTATTGCAAGAGACCAGAAAATTATTTTAAACATATAAAAGAAGCCTGTATTGTTTTGAATTTGAACGTCGGT TCTGCACTACTGCTGAAAGATGTACTGCAGTCAGCTTCAGGGCAGCTTCCTGCCACAGCAGCATTAAATGAAGTTGGAATTTACAAACTG >In-frame_AGAP1_ENST00000304032_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_1863nt ATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATC TACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGC CAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGG TACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTG CTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATA AGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGAT GCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACG TGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATA GGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAAT GGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACT GCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAG AAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCG TTGAATAAAGAGTGGAAAAAGAAATATGTCACCCTGTGTGACAATGGCGTGCTGACCTATCATCCCAGTTTACATTTCTTTCTACAACTT CAACAGGCTGCACTGGAGGTGTTTGCAGAGAATAATACTCTGAGTAAATTGCAGCTAGGACAGCTAGCCTCTATGGAGAGCTCTGTCTTT GATGACATGATTAACCTCTTAGAACGTTTAAAGCATGATATGTTGACCCGTCAAGTAGACCACGTTTTTAGAGAAGTTAAAGATGCTGCA AAATTGTATAAAAAAGAAAGATGGTTGTCCTTGCCATCTCAGTCAGAGCAGGCAGTGATGTCCCTGTCCAGTTCGGCTTGCCCGTTGCTG CTGACGTTACGAGACCATTTACTTCAGTTGGAGCAGCAGCTTTGTTTCTCCTTATTTAAAATTTTCTGGCAAATGCTTGTAGAGAAGCTG GATGTATACATCTACCAAGAAATAATTCTTGCTAATCACTTCAATGAAGGAGGAGCAGCCCAGCTGCAGTTTGATATGACTCGGAATCTT TTCCCTTTGTTTTCTCACTATTGCAAGAGACCAGAAAATTATTTTAAACATATAAAAGAAGCCTGTATTGTTTTGAATTTGAACGTCGGT TCTGCACTACTGCTGAAAGATGTACTGCAGTCAGCTTCAGGGCAGCTTCCTGCCACAGCAGCATTAAATGAAGTTGGAATTTACAAACTG >In-frame_AGAP1_ENST00000409538_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_2658nt ATGTACTTGTTGGACGGCAGTGGCGAGCCCGCGTCGCCACCCGCGGACGCGATGCCGCGCGGGACGCCCCCCAGAAAGACTGTCTACCGC ATCTCCGTGACCATGGTCAGGAAGGAGCAGCTGGCCGCGCCGGGCTCCGGCGGCCCGGACCCACGCCCGGTTCGGCGGCCCCGGCCCGCG CGCTCCCCGGACGCGCCCGGGAGGCTTGAGGAGGAGGCCGAGGAGGCGGAGGGCGCCGAGGAACCGGAGGGTCCCCGGCCGCGCGCTTGG GATTTCCGCACCTTCCGCACCCGCAGCACCGGGCAGCTGGAACTGGGGCGGCTCCGGCCGTGCGCACGCGGCCTGGAACCCGCGGACCTG GCCGGCAGCGCCCCGGCCGAGGAGGAGGGACGCGGCTCGCCCGCGTCCGGCAGCCCCGACGTGGAGGGGGCCCGGGCCGCGCCCCTGCGG CGGAGCCTGAGCTTCAGGCACTGGAGCGGGCCTGAGGCGCCGCAAGGCCGGACACTGGGCGGCGGAAGGCGCCACAGCAGCTCCGGGAGC CTGGCCTGGGCGCCGTGCGACGAGGCCGCGGCCGGGACCACCCTGGAGCCCGCGACCGCCACGCAGCCCGCCTCGGAGAAGCGCAACACC CTGGACGTGGGCGAGGTGCTCAGCAAGAACGACGCGCTCTCGGACCTGGAGCGTTGGGAACGCAGTAAGAGCAAGAACCGCACGCTGGAC AACAGCGACCTGCAGCGGCTGGAGCGCGCGCGGGCGGCGGCCGGGGCCGGCGCGGCCTCGGAGCACCGGCTGCTGCGCTTCTTCAGCGGC ATCTTCGCGCGCAGGGACGGGGGCCCGGGCGGCGGGCCCTCGCCACGGAGCGGAGCCTCGCGGCCACGCGGCTACTTCAGCCTGCGGCGG GCCCCGGCCGAAGCGCACTCGTCCAGCGCCGAGAGCATCGACGGCTCCCCGCGCAGAGATGCCTTCGTGAACAGCCAGGAATGGACGCTG AGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACA TATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAA GGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTT TACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCT AACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGG CTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCG CTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTA AGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACG CCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGT CGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCGTTGAATAAAGAGTGG AAAAAGAAATATGTCACCCTGTGTGACAATGGCGTGCTGACCTATCATCCCAGTTTACATTTCTTTCTACAACTTCAACAGGCTGCACTG GAGGTGTTTGCAGAGAATAATACTCTGAGTAAATTGCAGCTAGGACAGCTAGCCTCTATGGAGAGCTCTGTCTTTGATGACATGATTAAC CTCTTAGAACGTTTAAAGCATGATATGTTGACCCGTCAAGTAGACCACGTTTTTAGAGAAGTTAAAGATGCTGCAAAATTGTATAAAAAA GAAAGATGGTTGTCCTTGCCATCTCAGTCAGAGCAGGCAGTGATGTCCCTGTCCAGTTCGGCTTGCCCGTTGCTGCTGACGTTACGAGAC CATTTACTTCAGTTGGAGCAGCAGCTTTGTTTCTCCTTATTTAAAATTTTCTGGCAAATGCTTGTAGAGAAGCTGGATGTATACATCTAC CAAGAAATAATTCTTGCTAATCACTTCAATGAAGGAGGAGCAGCCCAGCTGCAGTTTGATATGACTCGGAATCTTTTCCCTTTGTTTTCT CACTATTGCAAGAGACCAGAAAATTATTTTAAACATATAAAAGAAGCCTGTATTGTTTTGAATTTGAACGTCGGTTCTGCACTACTGCTG AAAGATGTACTGCAGTCAGCTTCAGGGCAGCTTCCTGCCACAGCAGCATTAAATGAAGTTGGAATTTACAAACTGGCTCAACAAGATGTT >In-frame_AGAP1_ENST00000428334_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_1380nt ATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGAT GACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTC TTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGC CATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCC GTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCT AAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGG AGCGGCCGAGCCATCCCAATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCGTTGAATAAAGAGTGGAAAAAGAAATATGTCACC CTGTGTGACAATGGCGTGCTGACCTATCATCCCAGTTTACATTTCTTTCTACAACTTCAACAGGCTGCACTGGAGGTGTTTGCAGAGAAT AATACTCTGAGTAAATTGCAGCTAGGACAGCTAGCCTCTATGGAGAGCTCTGTCTTTGATGACATGATTAACCTCTTAGAACGTTTAAAG CATGATATGTTGACCCGTCAAGTAGACCACGTTTTTAGAGAAGTTAAAGATGCTGCAAAATTGTATAAAAAAGAAAGATGGTTGTCCTTG CCATCTCAGTCAGAGCAGGCAGTGATGTCCCTGTCCAGTTCGGCTTGCCCGTTGCTGCTGACGTTACGAGACCATTTACTTCAGTTGGAG CAGCAGCTTTGTTTCTCCTTATTTAAAATTTTCTGGCAAATGCTTGTAGAGAAGCTGGATGTATACATCTACCAAGAAATAATTCTTGCT AATCACTTCAATGAAGGAGGAGCAGCCCAGCTGCAGTTTGATATGACTCGGAATCTTTTCCCTTTGTTTTCTCACTATTGCAAGAGACCA GAAAATTATTTTAAACATATAAAAGAAGCCTGTATTGTTTTGAATTTGAACGTCGGTTCTGCACTACTGCTGAAAGATGTACTGCAGTCA GCTTCAGGGCAGCTTCCTGCCACAGCAGCATTAAATGAAGTTGGAATTTACAAACTGGCTCAACAAGATGTTGAGATTCTACTTAATTTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_AGAP1_ENST00000336665_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_2809nt CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCA GAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTC CGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAG CACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCT GTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCC AATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCGTTGAATAAAGAGTGGAAAAAGAAATATGTCACCCTGTGTGACAATGGCGT GCTGACCTATCATCCCAGTTTACATTTCTTTCTACAACTTCAACAGGCTGCACTGGAGGTGTTTGCAGAGAATAATACTCTGAGTAAATT GCAGCTAGGACAGCTAGCCTCTATGGAGAGCTCTGTCTTTGATGACATGATTAACCTCTTAGAACGTTTAAAGCATGATATGTTGACCCG TCAAGTAGACCACGTTTTTAGAGAAGTTAAAGATGCTGCAAAATTGTATAAAAAAGAAAGATGGTTGTCCTTGCCATCTCAGTCAGAGCA GGCAGTGATGTCCCTGTCCAGTTCGGCTTGCCCGTTGCTGCTGACGTTACGAGACCATTTACTTCAGTTGGAGCAGCAGCTTTGTTTCTC CTTATTTAAAATTTTCTGGCAAATGCTTGTAGAGAAGCTGGATGTATACATCTACCAAGAAATAATTCTTGCTAATCACTTCAATGAAGG AGGAGCAGCCCAGCTGCAGTTTGATATGACTCGGAATCTTTTCCCTTTGTTTTCTCACTATTGCAAGAGACCAGAAAATTATTTTAAACA TATAAAAGAAGCCTGTATTGTTTTGAATTTGAACGTCGGTTCTGCACTACTGCTGAAAGATGTACTGCAGTCAGCTTCAGGGCAGCTTCC TGCCACAGCAGCATTAAATGAAGTTGGAATTTACAAACTGGCTCAACAAGATGTTGAGATTCTACTTAATTTGAGGACAAATTGGCCTAA TACTGGAAAATAATGTCTTTCAGAAAAAGGTTTCTTTGGTTTTTGTTTCTAAGAAAGAGGAAGCCAATTGGATTTCAAGTTATATGATGA AATTCTGAATTAATGAAACTGGAAAACTTTATAGAATTACTTATTATCTTGGATTTATGGTGTTATTAAAATGCTGACCATATTTCCTTC ATCCTCTTGTTCCTAAGGAAACAAAAACAGAAAACGAAACAATGAAAACTCAATTCTATTTACAAGTATAAATGCTGAGTATGTCTGTTG AAGACGAGCAGAGATATTAAATTATAACCAACTTTCAATTTCCTGTGCTAATTAAGGGAAATTCTGTTGTGGATAATCAAACATAGCCAA >In-frame_AGAP1_ENST00000304032_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_2809nt CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCA GAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTC CGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAG CACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCT GTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCC AATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCGTTGAATAAAGAGTGGAAAAAGAAATATGTCACCCTGTGTGACAATGGCGT GCTGACCTATCATCCCAGTTTACATTTCTTTCTACAACTTCAACAGGCTGCACTGGAGGTGTTTGCAGAGAATAATACTCTGAGTAAATT GCAGCTAGGACAGCTAGCCTCTATGGAGAGCTCTGTCTTTGATGACATGATTAACCTCTTAGAACGTTTAAAGCATGATATGTTGACCCG TCAAGTAGACCACGTTTTTAGAGAAGTTAAAGATGCTGCAAAATTGTATAAAAAAGAAAGATGGTTGTCCTTGCCATCTCAGTCAGAGCA GGCAGTGATGTCCCTGTCCAGTTCGGCTTGCCCGTTGCTGCTGACGTTACGAGACCATTTACTTCAGTTGGAGCAGCAGCTTTGTTTCTC CTTATTTAAAATTTTCTGGCAAATGCTTGTAGAGAAGCTGGATGTATACATCTACCAAGAAATAATTCTTGCTAATCACTTCAATGAAGG AGGAGCAGCCCAGCTGCAGTTTGATATGACTCGGAATCTTTTCCCTTTGTTTTCTCACTATTGCAAGAGACCAGAAAATTATTTTAAACA TATAAAAGAAGCCTGTATTGTTTTGAATTTGAACGTCGGTTCTGCACTACTGCTGAAAGATGTACTGCAGTCAGCTTCAGGGCAGCTTCC TGCCACAGCAGCATTAAATGAAGTTGGAATTTACAAACTGGCTCAACAAGATGTTGAGATTCTACTTAATTTGAGGACAAATTGGCCTAA TACTGGAAAATAATGTCTTTCAGAAAAAGGTTTCTTTGGTTTTTGTTTCTAAGAAAGAGGAAGCCAATTGGATTTCAAGTTATATGATGA AATTCTGAATTAATGAAACTGGAAAACTTTATAGAATTACTTATTATCTTGGATTTATGGTGTTATTAAAATGCTGACCATATTTCCTTC ATCCTCTTGTTCCTAAGGAAACAAAAACAGAAAACGAAACAATGAAAACTCAATTCTATTTACAAGTATAAATGCTGAGTATGTCTGTTG AAGACGAGCAGAGATATTAAATTATAACCAACTTTCAATTTCCTGTGCTAATTAAGGGAAATTCTGTTGTGGATAATCAAACATAGCCAA >In-frame_AGAP1_ENST00000409538_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_3520nt GCGCGTTTCCATTTTAAACCGCCGCCCGCCGCCCGCCACCCGCCACCCTTCGGCCGCAGCCGGTGCAGCTGTCCGCGCGTCCCGGAGCCC AGGGAGTGGCGGAGGCTGCGGAACCGCCGAGCTGTGCAGCCGGAGCGGGAGGATGCGCACGGGCCCCGCGTCGTAGACAATGAAGCCGCG GGCGCCGCCGCCTGCCCTGGGCCCTGCGCACCGCGGCCGCACCTGCCGGCGAGAGCGCTCTAGCGCCTGACCGGCCGCCTCGCTTGGCCC CGCCGGCCCATGGCTCGGCGCCCCGGGCCCGGACCCCGGCACTCGGGCGGCGCGGCGCACGGGCCGGCGGGTGCCAGGGGCGCCGTCCCC GCAGCCTGAGTGCGGCCCTCGCGGTCAGCGGGGGGCGTGGGCCACACTCCCGGCCCGCCTGCCCTCCCCGCTTGGCCCGGCGCCCTCCCG GCCCGCGGGCTCGCTGGATGCGGCGGGGCCCCAGCGCGCGGGCGACATGTACTTGTTGGACGGCAGTGGCGAGCCCGCGTCGCCACCCGC GGACGCGATGCCGCGCGGGACGCCCCCCAGAAAGACTGTCTACCGCATCTCCGTGACCATGGTCAGGAAGGAGCAGCTGGCCGCGCCGGG CTCCGGCGGCCCGGACCCACGCCCGGTTCGGCGGCCCCGGCCCGCGCGCTCCCCGGACGCGCCCGGGAGGCTTGAGGAGGAGGCCGAGGA GGCGGAGGGCGCCGAGGAACCGGAGGGTCCCCGGCCGCGCGCTTGGGATTTCCGCACCTTCCGCACCCGCAGCACCGGGCAGCTGGAACT GGGGCGGCTCCGGCCGTGCGCACGCGGCCTGGAACCCGCGGACCTGGCCGGCAGCGCCCCGGCCGAGGAGGAGGGACGCGGCTCGCCCGC GTCCGGCAGCCCCGACGTGGAGGGGGCCCGGGCCGCGCCCCTGCGGCGGAGCCTGAGCTTCAGGCACTGGAGCGGGCCTGAGGCGCCGCA AGGCCGGACACTGGGCGGCGGAAGGCGCCACAGCAGCTCCGGGAGCCTGGCCTGGGCGCCGTGCGACGAGGCCGCGGCCGGGACCACCCT GGAGCCCGCGACCGCCACGCAGCCCGCCTCGGAGAAGCGCAACACCCTGGACGTGGGCGAGGTGCTCAGCAAGAACGACGCGCTCTCGGA CCTGGAGCGTTGGGAACGCAGTAAGAGCAAGAACCGCACGCTGGACAACAGCGACCTGCAGCGGCTGGAGCGCGCGCGGGCGGCGGCCGG GGCCGGCGCGGCCTCGGAGCACCGGCTGCTGCGCTTCTTCAGCGGCATCTTCGCGCGCAGGGACGGGGGCCCGGGCGGCGGGCCCTCGCC ACGGAGCGGAGCCTCGCGGCCACGCGGCTACTTCAGCCTGCGGCGGGCCCCGGCCGAAGCGCACTCGTCCAGCGCCGAGAGCATCGACGG CTCCCCGCGCAGAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTT GGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGA GATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGT TATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGA GATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAA CGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGT TGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGT GTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCA GAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTC TCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACA GGGCATGCTGTTGAAGCGAAGTGGCAAATCGTTGAATAAAGAGTGGAAAAAGAAATATGTCACCCTGTGTGACAATGGCGTGCTGACCTA TCATCCCAGTTTACATTTCTTTCTACAACTTCAACAGGCTGCACTGGAGGTGTTTGCAGAGAATAATACTCTGAGTAAATTGCAGCTAGG ACAGCTAGCCTCTATGGAGAGCTCTGTCTTTGATGACATGATTAACCTCTTAGAACGTTTAAAGCATGATATGTTGACCCGTCAAGTAGA CCACGTTTTTAGAGAAGTTAAAGATGCTGCAAAATTGTATAAAAAAGAAAGATGGTTGTCCTTGCCATCTCAGTCAGAGCAGGCAGTGAT GTCCCTGTCCAGTTCGGCTTGCCCGTTGCTGCTGACGTTACGAGACCATTTACTTCAGTTGGAGCAGCAGCTTTGTTTCTCCTTATTTAA AATTTTCTGGCAAATGCTTGTAGAGAAGCTGGATGTATACATCTACCAAGAAATAATTCTTGCTAATCACTTCAATGAAGGAGGAGCAGC CCAGCTGCAGTTTGATATGACTCGGAATCTTTTCCCTTTGTTTTCTCACTATTGCAAGAGACCAGAAAATTATTTTAAACATATAAAAGA AGCCTGTATTGTTTTGAATTTGAACGTCGGTTCTGCACTACTGCTGAAAGATGTACTGCAGTCAGCTTCAGGGCAGCTTCCTGCCACAGC AGCATTAAATGAAGTTGGAATTTACAAACTGGCTCAACAAGATGTTGAGATTCTACTTAATTTGAGGACAAATTGGCCTAATACTGGAAA ATAATGTCTTTCAGAAAAAGGTTTCTTTGGTTTTTGTTTCTAAGAAAGAGGAAGCCAATTGGATTTCAAGTTATATGATGAAATTCTGAA TTAATGAAACTGGAAAACTTTATAGAATTACTTATTATCTTGGATTTATGGTGTTATTAAAATGCTGACCATATTTCCTTCATCCTCTTG TTCCTAAGGAAACAAAAACAGAAAACGAAACAATGAAAACTCAATTCTATTTACAAGTATAAATGCTGAGTATGTCTGTTGAAGACGAGC AGAGATATTAAATTATAACCAACTTTCAATTTCCTGTGCTAATTAAGGGAAATTCTGTTGTGGATAATCAAACATAGCCAATAAATTTTT >In-frame_AGAP1_ENST00000428334_chr2_236792093_+_RINT1_ENST00000257700_chr7_105204180_+_1767nt GTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCT GCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATAC GGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAG TCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGT TTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCC ACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAG AGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCGTTGAATAAAGAG TGGAAAAAGAAATATGTCACCCTGTGTGACAATGGCGTGCTGACCTATCATCCCAGTTTACATTTCTTTCTACAACTTCAACAGGCTGCA CTGGAGGTGTTTGCAGAGAATAATACTCTGAGTAAATTGCAGCTAGGACAGCTAGCCTCTATGGAGAGCTCTGTCTTTGATGACATGATT AACCTCTTAGAACGTTTAAAGCATGATATGTTGACCCGTCAAGTAGACCACGTTTTTAGAGAAGTTAAAGATGCTGCAAAATTGTATAAA AAAGAAAGATGGTTGTCCTTGCCATCTCAGTCAGAGCAGGCAGTGATGTCCCTGTCCAGTTCGGCTTGCCCGTTGCTGCTGACGTTACGA GACCATTTACTTCAGTTGGAGCAGCAGCTTTGTTTCTCCTTATTTAAAATTTTCTGGCAAATGCTTGTAGAGAAGCTGGATGTATACATC TACCAAGAAATAATTCTTGCTAATCACTTCAATGAAGGAGGAGCAGCCCAGCTGCAGTTTGATATGACTCGGAATCTTTTCCCTTTGTTT TCTCACTATTGCAAGAGACCAGAAAATTATTTTAAACATATAAAAGAAGCCTGTATTGTTTTGAATTTGAACGTCGGTTCTGCACTACTG CTGAAAGATGTACTGCAGTCAGCTTCAGGGCAGCTTCCTGCCACAGCAGCATTAAATGAAGTTGGAATTTACAAACTGGCTCAACAAGAT GTTGAGATTCTACTTAATTTGAGGACAAATTGGCCTAATACTGGAAAATAATGTCTTTCAGAAAAAGGTTTCTTTGGTTTTTGTTTCTAA GAAAGAGGAAGCCAATTGGATTTCAAGTTATATGATGAAATTCTGAATTAATGAAACTGGAAAACTTTATAGAATTACTTATTATCTTGG ATTTATGGTGTTATTAAAATGCTGACCATATTTCCTTCATCCTCTTGTTCCTAAGGAAACAAAAACAGAAAACGAAACAATGAAAACTCA ATTCTATTTACAAGTATAAATGCTGAGTATGTCTGTTGAAGACGAGCAGAGATATTAAATTATAACCAACTTTCAATTTCCTGTGCTAAT |
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FusionGenePPI for AGAP1_RINT1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| AGAP1 | GRB7, TK1, SMN1, APP, SQSTM1, CBWD1, MIER2, XPO1, PRPF4, RHOA, ARF1, ARF6, RAC1, CDC42, P4HA3, PCDHA12, LZTS2, FLCN, PCDH20, PCDHA10, EPHA7, KCTD3, KIF13B, ZBTB21, KSR1, GIGYF1, LRFN1, DENND1A, SH3PXD2A, SRGAP2, EIF4E2, SIPA1L1, LIMA1, MAGI1, TESK2, DCLK1, ZNF638, SRSF12, SYDE1, CDC25B, CDK16, FAM110B, USP21, FAM53C, ANKRD34A, FAM110A, TBC1D25, PPM1H, MAPKAP1, MAST3, RTKN, DENND4C, HDAC4, RAB3IP, TIAM1, PHLDB2, NADK, GAB2, KIAA1804, NF1, CBY1, CGN, RASAL2, MELK, PLEKHA7, MLLT4, DEPDC1B, KIF1C, SH3BP4, CAMSAP2, PLEKHA5, NAV1, EDC3, TRIM25 | RINT1 | STX18, ZW10, RAD50, GFI1B, YLPM1, RBL2, RBL1, RB1, ARNT2, DCX, LMO2, PIK3R2, SMARCE1, STRN, HDAC4, FAM107A, SNW1, C1orf109, VPS37C, FAM90A1, RBM41, CCDC146, SH2D4A, RSRC2, SCNM1, ZNF655, CCDC121, FAM124B, CSPP1, EPC1, FAM110A, FAM161A, ZNF697, CCDC101, SFR1, CWF19L2, FAM81B, RIBC1, TXLNA, RTP5, CEP57L1, LSP1P3, USE1, BSG, CD274, GNAI2, F2RL1, NTRK1, SCLT1, SSX2IP, FOXL1, PTPRJ, SCFD2, NBAS, C19orf25, SPAG5, SEC22B, BNIP1, VIPR2, FZD10, APLNR, VAMP3, EPHA1, HTR2C, SIGLECL1, CHRM4, NAPA, OPRM1, TMEM206, PTPRN, SMARCB1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for AGAP1_RINT1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for AGAP1_RINT1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | AGAP1 | C0004352 | Autistic Disorder | 1 | CTD_human |
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