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Fusion gene ID: 10460 |
FusionGeneSummary for DPEP1_TCF25 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DPEP1_TCF25 | Fusion gene ID: 10460 | Hgene | Tgene | Gene symbol | DPEP1 | TCF25 | Gene ID | 1800 | 22980 |
| Gene name | dipeptidase 1 | transcription factor 25 | |
| Synonyms | MBD1|MDP|RDP | FKSG26|Hulp1|NULP1|PRO2620|hKIAA1049 | |
| Cytomap | 16q24.3 | 16q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | dipeptidase 1dehydropeptidase-Idipeptidase 1 (renal)hRDPmicrosomal dipeptidaserenal dipeptidasetesticular tissue protein Li 57 | transcription factor 25TCF-25nuclear localized protein 1transcription factor 25 (basic helix-loop-helix) | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P16444 | Q9BQ70 | |
| Ensembl transtripts involved in fusion gene | ENST00000421184, ENST00000393092, ENST00000261615, | ENST00000263346, ENST00000563406, ENST00000263347, | |
| Fusion gene scores | * DoF score | 1 X 2 X 2=4 | 5 X 6 X 3=90 |
| # samples | 8 | 13 | |
| ** MAII score | log2(8/4*10)=4.32192809488736 | log2(13/90*10)=0.53051471669878 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: DPEP1 [Title/Abstract] AND TCF25 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DPEP1 | GO:0016999 | antibiotic metabolic process | 8737157 |
| Hgene | DPEP1 | GO:0035690 | cellular response to drug | 20435919 |
| Hgene | DPEP1 | GO:0050667 | homocysteine metabolic process | 20031578 |
| Tgene | TCF25 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 16574069 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | COAD | TCGA-AY-A54L-01A | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| TCGA | LD | COAD | TCGA-CK-4947-01B | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
| TCGA | LD | COAD | TCGA-CK-6751-01A | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| TCGA | LD | COAD | TCGA-CM-6680-01A | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| TCGA | LD | COAD | TCGA-G4-6627-01A | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| TCGA | LD | READ | TCGA-CI-6622-01A | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
| TCGA | LD | READ | TCGA-F5-6861-01A | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| TCGA | LD | READ | TCGA-G5-6572-01A | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000421184 | ENST00000263346 | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| intron-intron | ENST00000421184 | ENST00000563406 | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| intron-intron | ENST00000421184 | ENST00000263347 | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| intron-3CDS | ENST00000393092 | ENST00000263346 | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| intron-intron | ENST00000393092 | ENST00000563406 | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| intron-intron | ENST00000393092 | ENST00000263347 | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| intron-3CDS | ENST00000261615 | ENST00000263346 | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| intron-intron | ENST00000261615 | ENST00000563406 | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| intron-intron | ENST00000261615 | ENST00000263347 | DPEP1 | chr16 | 89680127 | + | TCF25 | chr16 | 89976999 | + |
| In-frame | ENST00000421184 | ENST00000263346 | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
| 5CDS-intron | ENST00000421184 | ENST00000563406 | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
| 5CDS-intron | ENST00000421184 | ENST00000263347 | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
| In-frame | ENST00000393092 | ENST00000263346 | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
| 5CDS-intron | ENST00000393092 | ENST00000563406 | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
| 5CDS-intron | ENST00000393092 | ENST00000263347 | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
| In-frame | ENST00000261615 | ENST00000263346 | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
| 5CDS-intron | ENST00000261615 | ENST00000563406 | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
| 5CDS-intron | ENST00000261615 | ENST00000263347 | DPEP1 | chr16 | 89696922 | + | TCF25 | chr16 | 89976999 | + |
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FusionProtFeatures for DPEP1_TCF25 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DPEP1 | TCF25 |
| Hydrolyzes a wide range of dipeptides. Implicated in therenal metabolism of glutathione and its conjugates. Convertsleukotriene D4 to leukotriene E4; it may play an important role inthe regulation of leukotriene activity. | May play a role in cell death control. Acts as atranscriptional repressor. Has been shown to repress transcriptionof SRF in vitro and so may play a role in heart development.{ECO:0000269|PubMed:16574069}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for DPEP1_TCF25 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_DPEP1_ENST00000421184_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_112aa MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMAN >In-frame_DPEP1_ENST00000393092_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_112aa MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMAN >In-frame_DPEP1_ENST00000261615_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_112aa MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMAN >In-frame_DPEP1_ENST00000421184_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_112aa MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMAN >In-frame_DPEP1_ENST00000393092_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_112aa MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMAN >In-frame_DPEP1_ENST00000261615_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_112aa MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMAN |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_DPEP1_ENST00000421184_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_336nt ATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTCGGGACGAGGCAGAGAGGATCATGAGGGACTCC CCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCCGGTCACTGTTGCCAAACTATACCATGGAGGGG GAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGCTGATGCTGGCTGTGCGCGACATGATGGCCAAC >In-frame_DPEP1_ENST00000393092_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_336nt ATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTCGGGACGAGGCAGAGAGGATCATGAGGGACTCC CCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCCGGTCACTGTTGCCAAACTATACCATGGAGGGG GAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGCTGATGCTGGCTGTGCGCGACATGATGGCCAAC >In-frame_DPEP1_ENST00000261615_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_336nt ATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTCGGGACGAGGCAGAGAGGATCATGAGGGACTCC CCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCCGGTCACTGTTGCCAAACTATACCATGGAGGGG GAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGCTGATGCTGGCTGTGCGCGACATGATGGCCAAC >In-frame_DPEP1_ENST00000421184_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_336nt ATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTCGGGACGAGGCAGAGAGGATCATGAGGGACTCC CCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCCGGTCACTGTTGCCAAACTATACCATGGAGGGG GAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGCTGATGCTGGCTGTGCGCGACATGATGGCCAAC >In-frame_DPEP1_ENST00000393092_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_336nt ATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTCGGGACGAGGCAGAGAGGATCATGAGGGACTCC CCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCCGGTCACTGTTGCCAAACTATACCATGGAGGGG GAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGCTGATGCTGGCTGTGCGCGACATGATGGCCAAC >In-frame_DPEP1_ENST00000261615_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_336nt ATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTCGGGACGAGGCAGAGAGGATCATGAGGGACTCC CCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCCGGTCACTGTTGCCAAACTATACCATGGAGGGG GAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGCTGATGCTGGCTGTGCGCGACATGATGGCCAAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_DPEP1_ENST00000421184_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_685nt GGCACATCCACACATGAGGGAAAAACACTGCCAGGACATCTCAGGGCACTCTCAGGAAATGAGGAAGCTGCTGGAGAAGTTTCTAGCCTT GGGGGAGGCAGAGTGGCTCCTCACAGCCTGAAGCTCATCCTTCTGCACGGGCCAGCCAGGCCAGCACAGAGGCACCAGGGCAGCAGTGCA CACAGGTCCCCGGGGACCCCACCATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTCGGGACGAGG CAGAGAGGATCATGAGGGACTCCCCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCCGGTCACTGT TGCCAAACTATACCATGGAGGGGGAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGCTGATGCTGG CTGTGCGCGACATGATGGCCAACTTCCACCTCAACGACCTGGAGGCGCCGCACGAGGACGACGCTGAGGGGGAGGGGGAGTGGGACTGAG CGTCCGCAGAGGTGACCGAAAAGCCGTATGATGATGTTCCCGATTTCTCTGTTGGTCGGAGTCGGCCAGTTGCCTGAAGTAGGGAAGCTG >In-frame_DPEP1_ENST00000393092_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_773nt GGGGTACTGTGCGAGCCCTCAAGGAGGTGGCTGTTCTGTAGCTGGAGAGCTCCGTGGGTGGCAGGACTGAACTTGAACACCAGAAACAAC CCCCAAGCCTTGTGACCTGGGAGGCAGGAGGCGGGTCTGTCTCCCTGGGACTTGGGTGGCTGAGCCGAGGTACTCGGGACCCTGTCCCGC GCATGGCAGAGTGGCTCCTCACAGCCTGAAGCTCATCCTTCTGCACGGGCCAGCCAGGCCAGCACAGAGGCACCAGGGCAGCAGTGCACA CAGGTCCCCGGGGACCCCACCATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTCGGGACGAGGCA GAGAGGATCATGAGGGACTCCCCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCCGGTCACTGTTG CCAAACTATACCATGGAGGGGGAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGCTGATGCTGGCT GTGCGCGACATGATGGCCAACTTCCACCTCAACGACCTGGAGGCGCCGCACGAGGACGACGCTGAGGGGGAGGGGGAGTGGGACTGAGCG TCCGCAGAGGTGACCGAAAAGCCGTATGATGATGTTCCCGATTTCTCTGTTGGTCGGAGTCGGCCAGTTGCCTGAAGTAGGGAAGCTGAG >In-frame_DPEP1_ENST00000261615_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_604nt GTGCCTCTCCTGGCAGGCAGAGTGGCTCCTCACAGCCTGAAGCTCATCCTTCTGCACGGGCCAGCCAGGCCAGCACAGAGGCACCAGGGC AGCAGTGCACACAGGTCCCCGGGGACCCCACCATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTC GGGACGAGGCAGAGAGGATCATGAGGGACTCCCCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCC GGTCACTGTTGCCAAACTATACCATGGAGGGGGAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGC TGATGCTGGCTGTGCGCGACATGATGGCCAACTTCCACCTCAACGACCTGGAGGCGCCGCACGAGGACGACGCTGAGGGGGAGGGGGAGT GGGACTGAGCGTCCGCAGAGGTGACCGAAAAGCCGTATGATGATGTTCCCGATTTCTCTGTTGGTCGGAGTCGGCCAGTTGCCTGAAGTA >In-frame_DPEP1_ENST00000421184_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_685nt GGCACATCCACACATGAGGGAAAAACACTGCCAGGACATCTCAGGGCACTCTCAGGAAATGAGGAAGCTGCTGGAGAAGTTTCTAGCCTT GGGGGAGGCAGAGTGGCTCCTCACAGCCTGAAGCTCATCCTTCTGCACGGGCCAGCCAGGCCAGCACAGAGGCACCAGGGCAGCAGTGCA CACAGGTCCCCGGGGACCCCACCATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTCGGGACGAGG CAGAGAGGATCATGAGGGACTCCCCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCCGGTCACTGT TGCCAAACTATACCATGGAGGGGGAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGCTGATGCTGG CTGTGCGCGACATGATGGCCAACTTCCACCTCAACGACCTGGAGGCGCCGCACGAGGACGACGCTGAGGGGGAGGGGGAGTGGGACTGAG CGTCCGCAGAGGTGACCGAAAAGCCGTATGATGATGTTCCCGATTTCTCTGTTGGTCGGAGTCGGCCAGTTGCCTGAAGTAGGGAAGCTG >In-frame_DPEP1_ENST00000393092_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_773nt GGGGTACTGTGCGAGCCCTCAAGGAGGTGGCTGTTCTGTAGCTGGAGAGCTCCGTGGGTGGCAGGACTGAACTTGAACACCAGAAACAAC CCCCAAGCCTTGTGACCTGGGAGGCAGGAGGCGGGTCTGTCTCCCTGGGACTTGGGTGGCTGAGCCGAGGTACTCGGGACCCTGTCCCGC GCATGGCAGAGTGGCTCCTCACAGCCTGAAGCTCATCCTTCTGCACGGGCCAGCCAGGCCAGCACAGAGGCACCAGGGCAGCAGTGCACA CAGGTCCCCGGGGACCCCACCATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTCGGGACGAGGCA GAGAGGATCATGAGGGACTCCCCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCCGGTCACTGTTG CCAAACTATACCATGGAGGGGGAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGCTGATGCTGGCT GTGCGCGACATGATGGCCAACTTCCACCTCAACGACCTGGAGGCGCCGCACGAGGACGACGCTGAGGGGGAGGGGGAGTGGGACTGAGCG TCCGCAGAGGTGACCGAAAAGCCGTATGATGATGTTCCCGATTTCTCTGTTGGTCGGAGTCGGCCAGTTGCCTGAAGTAGGGAAGCTGAG >In-frame_DPEP1_ENST00000261615_chr16_89696922_+_TCF25_ENST00000263346_chr16_89976999_+_604nt GTGCCTCTCCTGGCAGGCAGAGTGGCTCCTCACAGCCTGAAGCTCATCCTTCTGCACGGGCCAGCCAGGCCAGCACAGAGGCACCAGGGC AGCAGTGCACACAGGTCCCCGGGGACCCCACCATGTGGAGCGGATGGTGGCTGTGGCCCCTTGTGGCCGTCTGCACTGCAGACTTCTTTC GGGACGAGGCAGAGAGGATCATGAGGGACTCCCCTGTCATTGATGGGCTAAGTCCTATCAGCCATGGAAACACCATTGCTCTCTTCTTCC GGTCACTGTTGCCAAACTATACCATGGAGGGGGAGAGGCCCGAGGAAGGAGTGGCTGGGGGTCTGAACCGCAACCAGGGCCTGAACAGGC TGATGCTGGCTGTGCGCGACATGATGGCCAACTTCCACCTCAACGACCTGGAGGCGCCGCACGAGGACGACGCTGAGGGGGAGGGGGAGT GGGACTGAGCGTCCGCAGAGGTGACCGAAAAGCCGTATGATGATGTTCCCGATTTCTCTGTTGGTCGGAGTCGGCCAGTTGCCTGAAGTA |
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FusionGenePPI for DPEP1_TCF25 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| DPEP1 | KIAA1279, DPEP1, APPBP2, TMUB2, FANCG, ORC5, SUN1, FLCN, STEAP3, NCAPD2, PIGA, NCAPG, C1GALT1, PICK1, ILVBL, VMP1, STEAP2, ALG10, HYAL2, ACADS, MDN1, GJA1, NCAPH, TMEM214, LMBR1, HPCAL1, ENDOD1, ZDHHC21, TMEM56, ALG8, ELOVL5, PIGQ, TBL2, TMEM181, GHITM, OSTC, SLC30A5, ABCB6, NDUFB3, ASIC1, RER1, FASTKD2, INTS2, UXS1, RDH11, GPAA1, PRAF2, NT5C3A, NDC1, SMC2, ALG6, TMEM120B, ATL2, GPR137, MTOR | TCF25 | SAT1, MAGEA11, NEK2, RPS10, XIAP, HSP90AA1, AGO1, GPRASP2, APPBP2, DERL1, CCDC155, CTSG, RPS2, FGL1, MRPL4, AAMP, XPO1, TSNAX, BCKDHB, DCAF5, SHPK, USP7, KLHL2, KIAA1683, PPAN, AMD1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DPEP1_TCF25 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DPEP1_TCF25 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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