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Fusion gene ID: 10350 |
FusionGeneSummary for DNMT1_OLFM2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DNMT1_OLFM2 | Fusion gene ID: 10350 | Hgene | Tgene | Gene symbol | DNMT1 | OLFM2 | Gene ID | 1786 | 93145 |
| Gene name | DNA methyltransferase 1 | olfactomedin 2 | |
| Synonyms | ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT|m.HsaI | NOE2|NOELIN2|NOELIN2_V1|OlfC | |
| Cytomap | 19p13.2 | 19p13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | DNA (cytosine-5)-methyltransferase 1CXXC-type zinc finger protein 9DNA (cytosine-5-)-methyltransferase 1DNA MTase HsaIDNA methyltransferase HsaI | noelin-2neuronal olfactomedin related ER localized protein 2 | |
| Modification date | 20180527 | 20180519 | |
| UniProtAcc | P26358 | O95897 | |
| Ensembl transtripts involved in fusion gene | ENST00000340748, ENST00000540357, ENST00000359526, ENST00000589538, | ENST00000264833, ENST00000590841, | |
| Fusion gene scores | * DoF score | 10 X 9 X 9=810 | 6 X 4 X 6=144 |
| # samples | 12 | 7 | |
| ** MAII score | log2(12/810*10)=-2.75488750216347 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/144*10)=-1.04064198449735 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DNMT1 [Title/Abstract] AND OLFM2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DNMT1 | GO:0010216 | maintenance of DNA methylation | 18754681|21745816 |
| Tgene | OLFM2 | GO:0009306 | protein secretion | 21228389 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-B6-A0WY-01A | DNMT1 | chr19 | 10341880 | - | OLFM2 | chr19 | 9971470 | - |
| TCGA | LD | ESCA | TCGA-L5-A43I-01A | DNMT1 | chr19 | 10246412 | - | OLFM2 | chr19 | 9968537 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000340748 | ENST00000264833 | DNMT1 | chr19 | 10341880 | - | OLFM2 | chr19 | 9971470 | - |
| intron-intron | ENST00000340748 | ENST00000590841 | DNMT1 | chr19 | 10341880 | - | OLFM2 | chr19 | 9971470 | - |
| intron-3CDS | ENST00000540357 | ENST00000264833 | DNMT1 | chr19 | 10341880 | - | OLFM2 | chr19 | 9971470 | - |
| intron-intron | ENST00000540357 | ENST00000590841 | DNMT1 | chr19 | 10341880 | - | OLFM2 | chr19 | 9971470 | - |
| intron-3CDS | ENST00000359526 | ENST00000264833 | DNMT1 | chr19 | 10341880 | - | OLFM2 | chr19 | 9971470 | - |
| intron-intron | ENST00000359526 | ENST00000590841 | DNMT1 | chr19 | 10341880 | - | OLFM2 | chr19 | 9971470 | - |
| intron-3CDS | ENST00000589538 | ENST00000264833 | DNMT1 | chr19 | 10341880 | - | OLFM2 | chr19 | 9971470 | - |
| intron-intron | ENST00000589538 | ENST00000590841 | DNMT1 | chr19 | 10341880 | - | OLFM2 | chr19 | 9971470 | - |
| In-frame | ENST00000340748 | ENST00000264833 | DNMT1 | chr19 | 10246412 | - | OLFM2 | chr19 | 9968537 | - |
| 5CDS-5UTR | ENST00000340748 | ENST00000590841 | DNMT1 | chr19 | 10246412 | - | OLFM2 | chr19 | 9968537 | - |
| In-frame | ENST00000540357 | ENST00000264833 | DNMT1 | chr19 | 10246412 | - | OLFM2 | chr19 | 9968537 | - |
| 5CDS-5UTR | ENST00000540357 | ENST00000590841 | DNMT1 | chr19 | 10246412 | - | OLFM2 | chr19 | 9968537 | - |
| In-frame | ENST00000359526 | ENST00000264833 | DNMT1 | chr19 | 10246412 | - | OLFM2 | chr19 | 9968537 | - |
| 5CDS-5UTR | ENST00000359526 | ENST00000590841 | DNMT1 | chr19 | 10246412 | - | OLFM2 | chr19 | 9968537 | - |
| intron-3CDS | ENST00000589538 | ENST00000264833 | DNMT1 | chr19 | 10246412 | - | OLFM2 | chr19 | 9968537 | - |
| intron-5UTR | ENST00000589538 | ENST00000590841 | DNMT1 | chr19 | 10246412 | - | OLFM2 | chr19 | 9968537 | - |
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FusionProtFeatures for DNMT1_OLFM2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DNMT1 | OLFM2 |
| Methylates CpG residues. Preferentially methylateshemimethylated DNA. Associates with DNA replication sites in Sphase maintaining the methylation pattern in the newly synthesizedstrand, that is essential for epigenetic inheritance. Associateswith chromatin during G2 and M phases to maintain DNA methylationindependently of replication. It is responsible for maintainingmethylation patterns established in development. DNA methylationis coordinated with methylation of histones. Mediatestranscriptional repression by direct binding to HDAC2. Inassociation with DNMT3B and via the recruitment of CTCFL/BORIS,involved in activation of BAG1 gene expression by modulatingdimethylation of promoter histone H3 at H3K4 and H3K9. Probablyforms a corepressor complex required for activated KRAS-mediatedpromoter hypermethylation and transcriptional silencing of tumorsuppressor genes (TSGs) or other tumor-related genes in colorectalcancer (CRC) cells (PubMed:24623306). Also required to maintain atranscriptionally repressive state of genes in undifferentiatedembryonic stem cells (ESCs) (PubMed:24623306). Associates atpromoter regions of tumor suppressor genes (TSGs) leading to theirgene silencing (PubMed:24623306). Promotes tumor growth(PubMed:24623306). {ECO:0000269|PubMed:16357870,ECO:0000269|PubMed:18413740, ECO:0000269|PubMed:18754681,ECO:0000269|PubMed:24623306}. | Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expressionand translocation of OLFM2 to the nucleus where it binds to SRF,causing its dissociation from the transcriptional repressorHEY2/HERP1 and facilitating binding of SRF to target genes(PubMed:25298399). Plays a role in AMPAR complex organization (Bysimilarity). Is a regulator of vascular smooth-muscle cell (SMC)phenotypic switching, that acts by promoting RUNX2 and inhibitingMYOCD binding to SRF. SMC phenotypic switching is the processthrough which vascular SMCs undergo transition between a quiescentcontractile phenotype and a proliferative synthetic phenotype inresponse to pathological stimuli. SMC phenotypic plasticity isessential for vascular development and remodeling (By similarity).{ECO:0000250|UniProtKB:Q568Y7, ECO:0000250|UniProtKB:Q8BM13,ECO:0000269|PubMed:25298399}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 755_880 | 1575 | 1617 | Domain | BAH 1 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 972_1100 | 1575 | 1617 | Domain | BAH 2 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 755_880 | 1591 | 1633 | Domain | BAH 1 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 972_1100 | 1591 | 1633 | Domain | BAH 2 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 177_205 | 1575 | 1617 | Motif | Nuclear localization signal |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 177_205 | 1591 | 1633 | Motif | Nuclear localization signal |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1109_1120 | 1575 | 1617 | Region | Note=6 X 2 AA tandem repeats of K-G |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1150_1151 | 1575 | 1617 | Region | S-adenosyl-L-methionine binding |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1168_1169 | 1575 | 1617 | Region | S-adenosyl-L-methionine binding |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1190_1191 | 1575 | 1617 | Region | S-adenosyl-L-methionine binding |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 310_502 | 1575 | 1617 | Region | Note=Homodimerization |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 331_550 | 1575 | 1617 | Region | DNA replication foci-targeting sequence |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 651_697 | 1575 | 1617 | Region | Note=Required for activity |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 693_754 | 1575 | 1617 | Region | Note=Autoinhibitory linker |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1109_1120 | 1591 | 1633 | Region | Note=6 X 2 AA tandem repeats of K-G |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1150_1151 | 1591 | 1633 | Region | S-adenosyl-L-methionine binding |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1168_1169 | 1591 | 1633 | Region | S-adenosyl-L-methionine binding |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1190_1191 | 1591 | 1633 | Region | S-adenosyl-L-methionine binding |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 310_502 | 1591 | 1633 | Region | Note=Homodimerization |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 331_550 | 1591 | 1633 | Region | DNA replication foci-targeting sequence |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 651_697 | 1591 | 1633 | Region | Note=Required for activity |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 693_754 | 1591 | 1633 | Region | Note=Autoinhibitory linker |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1109_1110 | 1575 | 1617 | Repeat | Note=1 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1111_1112 | 1575 | 1617 | Repeat | Note=2 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1113_1114 | 1575 | 1617 | Repeat | Note=3 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1115_1116 | 1575 | 1617 | Repeat | Note=4 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1117_1118 | 1575 | 1617 | Repeat | Note=5 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1119_1120 | 1575 | 1617 | Repeat | Note=6%3B approximate |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1109_1110 | 1591 | 1633 | Repeat | Note=1 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1111_1112 | 1591 | 1633 | Repeat | Note=2 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1113_1114 | 1591 | 1633 | Repeat | Note=3 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1115_1116 | 1591 | 1633 | Repeat | Note=4 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1117_1118 | 1591 | 1633 | Repeat | Note=5 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1119_1120 | 1591 | 1633 | Repeat | Note=6%3B approximate |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 646_692 | 1575 | 1617 | Zinc finger | CXXC-type |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 646_692 | 1591 | 1633 | Zinc finger | CXXC-type |
| Tgene | >OLFM2 | chr19:10246412 | chr19:9968537 | ENST00000264833 | - | 1 | 6 | 136_193 | 71 | 455 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >OLFM2 | chr19:10246412 | chr19:9968537 | ENST00000264833 | - | 1 | 6 | 194_446 | 71 | 455 | Domain | Olfactomedin-like |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1139_1599 | 1575 | 1617 | Domain | SAM-dependent MTase C5-type |
| Hgene | >DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1139_1599 | 1591 | 1633 | Domain | SAM-dependent MTase C5-type |
| Hgene | >DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1139_1616 | 1575 | 1617 | Region | Note=Catalytic |
| Hgene | >DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1139_1616 | 1591 | 1633 | Region | Note=Catalytic |
| Tgene | OLFM2 | chr19:10246412 | chr19:9968537 | ENST00000264833 | - | 1 | 6 | 58_85 | 71 | 455 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for DNMT1_OLFM2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_DNMT1_ENST00000340748_chr19_10246412_-_OLFM2_ENST00000264833_chr19_9968537_-_1959aa MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDL SLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKP QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGV QADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYL DDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLE GGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGL NLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDT FFAEQIEKDDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQ GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSD PLELFLVDECEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLA EMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEP YRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGP NRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQACEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMW DPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRP RFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKF VSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLP NIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNP EPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADGSLSA KSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGSLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPIT VRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSR SVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVMRSWDTGYPKRSAGEAFMICGVLYVTNSH >In-frame_DNMT1_ENST00000540357_chr19_10246412_-_OLFM2_ENST00000264833_chr19_9968537_-_1962aa MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDL SLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKP QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGV QADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYL DDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLE GGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGL NLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDT FFAEQIEKDDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQ GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSD PLELFLVDECEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLA EMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEP YRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGP NRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQACEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMW DPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRP RFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKF VSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLP NIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEGGSSGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTV TNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADGS LSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGSLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSN PITVRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHF RSRSVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVMRSWDTGYPKRSAGEAFMICGVLYVT >In-frame_DNMT1_ENST00000359526_chr19_10246412_-_OLFM2_ENST00000264833_chr19_9968537_-_1975aa MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDL SLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQ TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTP KQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELF FSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQARRQTIRHSTREKDRG PTKATTTKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHA HWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLSSPVKRPRKEPVDEDLYPEHYR KYSDYIKGSNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQACEPSEPEIEIKLPKLRTLDVFSGCGGLSEG FHQAGISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVF APRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLY GRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVQNVSQSMEVLELRTYRDLQYVRGMETLM RSLDARLRAADGSLSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGSLAAIQEEMGAYGYEDLQQRVMALEARLHACA QKLGCGKLTGVSNPITVRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFY NKYQSNVVVKYHFRSRSVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVMRSWDTGYPKRSA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_DNMT1_ENST00000340748_chr19_10246412_-_OLFM2_ENST00000264833_chr19_9968537_-_5877nt ATGCCGGCGCGTACCGCCCCAGCCCGGGTGCCCACACTGGCCGTCCCGGCCATCTCGCTGCCCGACGATGTCCGCAGGCGGCTCAAAGAT TTGGAAAGAGACAGCTTAACAGAAAAGGAATGTGTGAAGGAGAAATTGAATCTCTTGCACGAATTTCTGCAAACAGAAATAAAGAATCAG TTATGTGACTTGGAAACCAAATTACGTAAAGAAGAATTATCCGAGGAGGGCTACCTGGCTAAAGTCAAATCCCTTTTAAATAAAGATTTG TCCTTGGAGAACGGTGCTCATGCTTACAACCGGGAAGTGAATGGACGTCTAGAAAACGGGAACCAAGCAAGAAGTGAAGCCCGTAGAGTG GGAATGGCAGATGCCAACAGCCCCCCCAAACCCCTTTCCAAACCTCGCACGCCCAGGAGGAGCAAGTCCGATGGAGAGGCTAAGCCTGAA CCTTCACCTAGCCCCAGGATTACAAGGAAAAGCACCAGGCAAACCACCATCACATCTCATTTTGCAAAGGGCCCTGCCAAACGGAAACCT CAGGAAGAGTCTGAAAGAGCCAAATCGGATGAGTCCATCAAGGAAGAAGACAAAGACCAGGATGAGAAGAGACGTAGAGTTACATCCAGA GAACGAGTTGCTAGACCGCTTCCTGCAGAAGAACCTGAAAGAGCAAAATCAGGAACGCGCACTGAAAAGGAAGAAGAAAGAGATGAAAAA GAAGAAAAGAGACTCCGAAGTCAAACCAAAGAACCAACACCCAAACAGAAACTGAAGGAGGAGCCGGACAGAGAAGCCAGGGCAGGCGTG CAGGCTGACGAGGACGAAGATGGAGACGAGAAAGATGAGAAGAAGCACAGAAGTCAACCCAAAGATCTAGCTGCCAAACGGAGGCCCGAA GAAAAAGAACCTGAAAAAGTAAATCCACAGATTTCTGATGAAAAAGACGAGGATGAAAAGGAGGAGAAGAGACGCAAAACGACCCCCAAA GAACCAACGGAGAAAAAAATGGCTCGCGCCAAAACAGTCATGAACTCCAAGACCCACCCTCCCAAGTGCATTCAGTGCGGGCAGTACCTG GACGACCCTGACCTCAAATATGGGCAGCACCCACCAGACGCGGTGGATGAGCCACAGATGCTGACAAATGAGAAGCTGTCCATCTTTGAT GCCAACGAGTCTGGCTTTGAGAGTTATGAGGCGCTTCCCCAGCACAAACTGACCTGCTTCAGTGTGTACTGTAAGCACGGTCACCTGTGT CCCATCGACACCGGCCTCATCGAGAAGAATATCGAACTCTTCTTTTCTGGTTCAGCAAAACCAATCTATGATGATGACCCATCTCTTGAA GGTGGTGTTAATGGCAAAAATCTTGGCCCCATAAATGAATGGTGGATCACTGGCTTTGATGGAGGTGAAAAGGCCCTCATCGGCTTCAGC ACCTCATTTGCCGAATACATTCTGATGGATCCCAGTCCCGAGTATGCGCCCATATTTGGGCTGATGCAGGAGAAGATCTACATCAGCAAG ATTGTGGTGGAGTTCCTGCAGAGCAATTCCGACTCGACCTATGAGGACCTGATCAACAAGATCGAGACCACGGTTCCTCCTTCTGGCCTC AACTTGAACCGCTTCACAGAGGACTCCCTCCTGCGACACGCGCAGTTTGTGGTGGAGCAGGTGGAGAGTTATGACGAGGCCGGGGACAGT GATGAGCAGCCCATCTTCCTGACACCCTGCATGCGGGACCTGATCAAGCTGGCTGGGGTCACGCTGGGACAGAGGCGAGCCCAGGCGAGG CGGCAGACCATCAGGCATTCTACCAGGGAGAAGGACAGGGGACCCACGAAAGCCACCACCACCAAGCTGGTCTACCAGATCTTCGATACT TTCTTCGCAGAGCAAATTGAAAAGGATGACAGAGAAGACAAGGAGAACGCCTTTAAGCGCCGGCGATGTGGCGTCTGTGAGGTGTGTCAG CAGCCTGAGTGTGGGAAATGTAAAGCCTGCAAGGACATGGTTAAATTTGGTGGCAGTGGACGGAGCAAGCAGGCTTGCCAAGAGCGGAGG TGTCCCAATATGGCCATGAAGGAGGCAGATGACGATGAGGAAGTCGATGATAACATCCCAGAGATGCCGTCACCCAAAAAAATGCACCAG GGGAAGAAGAAGAAACAGAACAAGAATCGCATCTCTTGGGTCGGAGAAGCCGTCAAGACTGATGGGAAGAAGAGTTACTATAAGAAGGTG TGCATTGATGCGGAAACCCTGGAAGTGGGGGACTGTGTCTCTGTTATTCCAGATGATTCCTCAAAACCGCTGTATCTAGCAAGGGTCACG GCGCTGTGGGAGGACAGCAGCAACGGGCAGATGTTTCACGCCCACTGGTTCTGCGCTGGGACAGACACAGTCCTCGGGGCCACGTCGGAC CCTCTGGAGCTGTTCTTGGTGGATGAATGTGAGGACATGCAGCTTTCATATATCCACAGCAAAGTGAAAGTCATCTACAAAGCCCCCTCC GAAAACTGGGCCATGGAGGGAGGCATGGATCCCGAGTCCCTGCTGGAGGGGGACGACGGGAAGACCTACTTCTACCAGCTGTGGTATGAT CAAGACTACGCGAGATTCGAGTCCCCTCCAAAAACCCAGCCAACAGAGGACAACAAGTTCAAATTCTGTGTGAGCTGTGCCCGTCTGGCT GAGATGAGGCAAAAAGAAATCCCCAGGGTCCTGGAGCAGCTCGAGGACCTGGATAGCCGGGTCCTCTACTACTCAGCCACCAAGAACGGC ATCCTGTACCGAGTTGGTGATGGTGTGTACCTGCCCCCTGAGGCCTTCACGTTCAACATCAAGCTGTCCAGTCCCGTGAAACGCCCACGG AAGGAGCCCGTGGATGAGGACCTGTACCCAGAGCACTACCGGAAATACTCCGACTACATCAAAGGCAGCAACCTGGATGCCCCTGAGCCC TACCGAATTGGCCGGATCAAAGAGATCTTCTGTCCCAAGAAGAGCAACGGCAGGCCCAATGAGACTGACATCAAAATCCGGGTCAACAAG TTCTACAGGCCTGAGAACACCCACAAGTCCACTCCAGCGAGCTACCACGCAGACATCAACCTGCTCTACTGGAGCGACGAGGAGGCCGTG GTGGACTTCAAGGCTGTGCAGGGCCGCTGCACCGTGGAGTATGGGGAGGACCTGCCCGAGTGCGTCCAGGTGTACTCCATGGGCGGCCCC AACCGCTTCTACTTCCTCGAGGCCTATAATGCAAAGAGCAAAAGCTTTGAAGATCCTCCCAACCATGCCCGTAGCCCTGGAAACAAAGGG AAGGGCAAGGGAAAAGGGAAGGGCAAGCCCAAGTCCCAAGCCTGTGAGCCGAGCGAGCCAGAGATAGAGATCAAGCTGCCCAAGCTGCGG ACCCTGGATGTGTTTTCTGGCTGCGGGGGGTTGTCGGAGGGATTCCACCAAGCAGGCATCTCTGACACGCTGTGGGCCATCGAGATGTGG GACCCTGCGGCCCAGGCGTTCCGGCTGAACAACCCCGGCTCCACAGTGTTCACAGAGGACTGCAACATCCTGCTGAAGCTGGTCATGGCT GGGGAGACCACCAACTCCCGCGGCCAGCGGCTGCCCCAGAAGGGAGACGTGGAGATGCTGTGCGGCGGGCCGCCCTGCCAGGGCTTCAGC GGCATGAACCGCTTCAATTCGCGCACCTACTCCAAGTTCAAAAACTCTCTGGTGGTTTCCTTCCTCAGCTACTGCGACTACTACCGGCCC CGGTTCTTCCTCCTGGAGAATGTCAGGAACTTTGTCTCCTTCAAGCGCTCCATGGTCCTGAAGCTCACCCTCCGCTGCCTGGTCCGCATG GGCTATCAGTGCACCTTCGGCGTGCTGCAGGCCGGTCAGTACGGCGTGGCCCAGACTAGGAGGCGGGCCATCATCCTGGCCGCGGCCCCT GGAGAGAAGCTCCCTCTGTTCCCGGAGCCACTGCACGTGTTTGCTCCCCGGGCCTGCCAGCTGAGCGTGGTGGTGGATGACAAGAAGTTT GTGAGCAACATAACCAGGTTGAGCTCGGGTCCTTTCCGGACCATCACGGTGCGAGACACGATGTCCGACCTGCCGGAGGTGCGGAATGGA GCCTCGGCACTGGAGATCTCCTACAACGGGGAGCCTCAGTCCTGGTTCCAGAGGCAGCTCCGGGGCGCACAGTACCAGCCCATCCTCAGG GACCACATCTGTAAGGACATGAGTGCATTGGTGGCTGCCCGCATGCGGCACATCCCCTTGGCCCCAGGGTCAGACTGGCGCGATCTGCCC AACATCGAGGTGCGGCTCTCAGACGGCACCATGGCCAGGAAGCTGCGGTATACCCACCATGACAGGAAGAACGGCCGCAGCAGCTCTGGG GCCCTCCGTGGGGTCTGCTCCTGCGTGGAAGCCGGCAAAGCCTGCGACCCCGCAGCCAGGCAGTTCAACACCCTCATCCCCTGGTGCCTG CCCCACACCGGGAACCGGCACAACCACTGGGCTGGCCTCTATGGAAGGCTCGAGTGGGACGGCTTCTTCAGCACAACCGTCACCAACCCC GAGCCCATGGGCAAGCAGGGCCGCGTGCTCCACCCAGAGCAGCACCGTGTGGTGAGCGTGCGGGAGTGTGCCCGCTCCCAGGGCTTCCCT GACACCTACCGGCTCTTCGGCAACATCCTGGACAAGCACCGGCAGGTCCAGAACGTCTCCCAGTCCATGGAGGTCCTTGAGTTGCGGACG TATCGCGACCTCCAGTATGTACGCGGCATGGAGACCCTCATGCGGAGCCTGGATGCGCGGCTCCGGGCAGCTGATGGGTCCCTCTCGGCC AAGAGCTTCCAGGAGCTGAAGGACAGGATGACGGAACTGTTGCCCCTGAGCTCGGTCCTGGAGCAGTACAAGGCAGACACGCGGACCATT GTACGCTTGCGGGAGGAGGTGAGGAATCTCTCCGGCAGTCTGGCGGCCATTCAGGAGGAGATGGGTGCCTACGGGTATGAGGACCTGCAG CAACGGGTGATGGCCCTGGAGGCCCGGCTCCACGCCTGCGCCCAGAAGCTGGGCTGTGGGAAGCTGACCGGGGTCAGTAACCCCATCACC GTTCGGGCCATGGGGTCCCGCTTCGGCTCCTGGATGACTGACACGATGGCCCCCAGTGCGGATAGCCGGGTCTGGTACATGGATGGCTAT TACAAAGGCCGCCGGGTCCTGGAGTTCCGTACCCTGGGAGACTTCATCAAAGGCCAGAACTTTATCCAGCACCTGCTGCCCCAGCCGTGG GCGGGCACGGGCCACGTGGTGTACAACGGCTCCCTGTTCTATAACAAGTACCAGAGCAACGTGGTGGTCAAATACCACTTCCGCTCGCGC TCTGTGCTGGTGCAGAGGAGCCTCCCGGGCGCCGGTTACAACAACACCTTCCCCTACTCCTGGGGCGGCTTCTCCGACATGGACTTCATG GTGGACGAGAGCGGGCTCTGGGCTGTGTACACCACCAACCAGAACGCGGGCAACATCGTGGTCAGCCGGCTGGACCCGCACACCCTCGAG GTCATGCGGTCCTGGGACACCGGCTACCCCAAGCGCAGCGCTGGCGAGGCCTTCATGATCTGCGGTGTGCTCTACGTGACCAACTCCCAC CTGGCTGGGGCCAAGGTCTACTTCGCCTATTTTACCAACACGTCCAGTTACGAGTACACGGACGTGCCCTTCCACAACCAGTATTCCCAC ATCTCGATGCTGGATTACAACCCCCGGGAGCGCGCCCTCTATACCTGGAACAACGGCCACCAGGTGCTCTACAATGTCACCCTGTTTCAC >In-frame_DNMT1_ENST00000540357_chr19_10246412_-_OLFM2_ENST00000264833_chr19_9968537_-_5886nt ATGCCGGCGCGTACCGCCCCAGCCCGGGTGCCCACACTGGCCGTCCCGGCCATCTCGCTGCCCGACGATGTCCGCAGGCGGCTCAAAGAT TTGGAAAGAGACAGCTTAACAGAAAAGGAATGTGTGAAGGAGAAATTGAATCTCTTGCACGAATTTCTGCAAACAGAAATAAAGAATCAG TTATGTGACTTGGAAACCAAATTACGTAAAGAAGAATTATCCGAGGAGGGCTACCTGGCTAAAGTCAAATCCCTTTTAAATAAAGATTTG TCCTTGGAGAACGGTGCTCATGCTTACAACCGGGAAGTGAATGGACGTCTAGAAAACGGGAACCAAGCAAGAAGTGAAGCCCGTAGAGTG GGAATGGCAGATGCCAACAGCCCCCCCAAACCCCTTTCCAAACCTCGCACGCCCAGGAGGAGCAAGTCCGATGGAGAGGCTAAGCCTGAA CCTTCACCTAGCCCCAGGATTACAAGGAAAAGCACCAGGCAAACCACCATCACATCTCATTTTGCAAAGGGCCCTGCCAAACGGAAACCT CAGGAAGAGTCTGAAAGAGCCAAATCGGATGAGTCCATCAAGGAAGAAGACAAAGACCAGGATGAGAAGAGACGTAGAGTTACATCCAGA GAACGAGTTGCTAGACCGCTTCCTGCAGAAGAACCTGAAAGAGCAAAATCAGGAACGCGCACTGAAAAGGAAGAAGAAAGAGATGAAAAA GAAGAAAAGAGACTCCGAAGTCAAACCAAAGAACCAACACCCAAACAGAAACTGAAGGAGGAGCCGGACAGAGAAGCCAGGGCAGGCGTG CAGGCTGACGAGGACGAAGATGGAGACGAGAAAGATGAGAAGAAGCACAGAAGTCAACCCAAAGATCTAGCTGCCAAACGGAGGCCCGAA GAAAAAGAACCTGAAAAAGTAAATCCACAGATTTCTGATGAAAAAGACGAGGATGAAAAGGAGGAGAAGAGACGCAAAACGACCCCCAAA GAACCAACGGAGAAAAAAATGGCTCGCGCCAAAACAGTCATGAACTCCAAGACCCACCCTCCCAAGTGCATTCAGTGCGGGCAGTACCTG GACGACCCTGACCTCAAATATGGGCAGCACCCACCAGACGCGGTGGATGAGCCACAGATGCTGACAAATGAGAAGCTGTCCATCTTTGAT GCCAACGAGTCTGGCTTTGAGAGTTATGAGGCGCTTCCCCAGCACAAACTGACCTGCTTCAGTGTGTACTGTAAGCACGGTCACCTGTGT CCCATCGACACCGGCCTCATCGAGAAGAATATCGAACTCTTCTTTTCTGGTTCAGCAAAACCAATCTATGATGATGACCCATCTCTTGAA GGTGGTGTTAATGGCAAAAATCTTGGCCCCATAAATGAATGGTGGATCACTGGCTTTGATGGAGGTGAAAAGGCCCTCATCGGCTTCAGC ACCTCATTTGCCGAATACATTCTGATGGATCCCAGTCCCGAGTATGCGCCCATATTTGGGCTGATGCAGGAGAAGATCTACATCAGCAAG ATTGTGGTGGAGTTCCTGCAGAGCAATTCCGACTCGACCTATGAGGACCTGATCAACAAGATCGAGACCACGGTTCCTCCTTCTGGCCTC AACTTGAACCGCTTCACAGAGGACTCCCTCCTGCGACACGCGCAGTTTGTGGTGGAGCAGGTGGAGAGTTATGACGAGGCCGGGGACAGT GATGAGCAGCCCATCTTCCTGACACCCTGCATGCGGGACCTGATCAAGCTGGCTGGGGTCACGCTGGGACAGAGGCGAGCCCAGGCGAGG CGGCAGACCATCAGGCATTCTACCAGGGAGAAGGACAGGGGACCCACGAAAGCCACCACCACCAAGCTGGTCTACCAGATCTTCGATACT TTCTTCGCAGAGCAAATTGAAAAGGATGACAGAGAAGACAAGGAGAACGCCTTTAAGCGCCGGCGATGTGGCGTCTGTGAGGTGTGTCAG CAGCCTGAGTGTGGGAAATGTAAAGCCTGCAAGGACATGGTTAAATTTGGTGGCAGTGGACGGAGCAAGCAGGCTTGCCAAGAGCGGAGG TGTCCCAATATGGCCATGAAGGAGGCAGATGACGATGAGGAAGTCGATGATAACATCCCAGAGATGCCGTCACCCAAAAAAATGCACCAG GGGAAGAAGAAGAAACAGAACAAGAATCGCATCTCTTGGGTCGGAGAAGCCGTCAAGACTGATGGGAAGAAGAGTTACTATAAGAAGGTG TGCATTGATGCGGAAACCCTGGAAGTGGGGGACTGTGTCTCTGTTATTCCAGATGATTCCTCAAAACCGCTGTATCTAGCAAGGGTCACG GCGCTGTGGGAGGACAGCAGCAACGGGCAGATGTTTCACGCCCACTGGTTCTGCGCTGGGACAGACACAGTCCTCGGGGCCACGTCGGAC CCTCTGGAGCTGTTCTTGGTGGATGAATGTGAGGACATGCAGCTTTCATATATCCACAGCAAAGTGAAAGTCATCTACAAAGCCCCCTCC GAAAACTGGGCCATGGAGGGAGGCATGGATCCCGAGTCCCTGCTGGAGGGGGACGACGGGAAGACCTACTTCTACCAGCTGTGGTATGAT CAAGACTACGCGAGATTCGAGTCCCCTCCAAAAACCCAGCCAACAGAGGACAACAAGTTCAAATTCTGTGTGAGCTGTGCCCGTCTGGCT GAGATGAGGCAAAAAGAAATCCCCAGGGTCCTGGAGCAGCTCGAGGACCTGGATAGCCGGGTCCTCTACTACTCAGCCACCAAGAACGGC ATCCTGTACCGAGTTGGTGATGGTGTGTACCTGCCCCCTGAGGCCTTCACGTTCAACATCAAGCTGTCCAGTCCCGTGAAACGCCCACGG AAGGAGCCCGTGGATGAGGACCTGTACCCAGAGCACTACCGGAAATACTCCGACTACATCAAAGGCAGCAACCTGGATGCCCCTGAGCCC TACCGAATTGGCCGGATCAAAGAGATCTTCTGTCCCAAGAAGAGCAACGGCAGGCCCAATGAGACTGACATCAAAATCCGGGTCAACAAG TTCTACAGGCCTGAGAACACCCACAAGTCCACTCCAGCGAGCTACCACGCAGACATCAACCTGCTCTACTGGAGCGACGAGGAGGCCGTG GTGGACTTCAAGGCTGTGCAGGGCCGCTGCACCGTGGAGTATGGGGAGGACCTGCCCGAGTGCGTCCAGGTGTACTCCATGGGCGGCCCC AACCGCTTCTACTTCCTCGAGGCCTATAATGCAAAGAGCAAAAGCTTTGAAGATCCTCCCAACCATGCCCGTAGCCCTGGAAACAAAGGG AAGGGCAAGGGAAAAGGGAAGGGCAAGCCCAAGTCCCAAGCCTGTGAGCCGAGCGAGCCAGAGATAGAGATCAAGCTGCCCAAGCTGCGG ACCCTGGATGTGTTTTCTGGCTGCGGGGGGTTGTCGGAGGGATTCCACCAAGCAGGCATCTCTGACACGCTGTGGGCCATCGAGATGTGG GACCCTGCGGCCCAGGCGTTCCGGCTGAACAACCCCGGCTCCACAGTGTTCACAGAGGACTGCAACATCCTGCTGAAGCTGGTCATGGCT GGGGAGACCACCAACTCCCGCGGCCAGCGGCTGCCCCAGAAGGGAGACGTGGAGATGCTGTGCGGCGGGCCGCCCTGCCAGGGCTTCAGC GGCATGAACCGCTTCAATTCGCGCACCTACTCCAAGTTCAAAAACTCTCTGGTGGTTTCCTTCCTCAGCTACTGCGACTACTACCGGCCC CGGTTCTTCCTCCTGGAGAATGTCAGGAACTTTGTCTCCTTCAAGCGCTCCATGGTCCTGAAGCTCACCCTCCGCTGCCTGGTCCGCATG GGCTATCAGTGCACCTTCGGCGTGCTGCAGGCCGGTCAGTACGGCGTGGCCCAGACTAGGAGGCGGGCCATCATCCTGGCCGCGGCCCCT GGAGAGAAGCTCCCTCTGTTCCCGGAGCCACTGCACGTGTTTGCTCCCCGGGCCTGCCAGCTGAGCGTGGTGGTGGATGACAAGAAGTTT GTGAGCAACATAACCAGGTTGAGCTCGGGTCCTTTCCGGACCATCACGGTGCGAGACACGATGTCCGACCTGCCGGAGGTGCGGAATGGA GCCTCGGCACTGGAGATCTCCTACAACGGGGAGCCTCAGTCCTGGTTCCAGAGGCAGCTCCGGGGCGCACAGTACCAGCCCATCCTCAGG GACCACATCTGTAAGGACATGAGTGCATTGGTGGCTGCCCGCATGCGGCACATCCCCTTGGCCCCAGGGTCAGACTGGCGCGATCTGCCC AACATCGAGGTGCGGCTCTCAGACGGCACCATGGCCAGGAAGCTGCGGTATACCCACCATGACAGGAAGAACGGCCGCAGCAGCTCTGGG GCCCTCCGTGGGGTCTGCTCCTGCGTGGAAGGTGGGTCCTCCGGCAAAGCCTGCGACCCCGCAGCCAGGCAGTTCAACACCCTCATCCCC TGGTGCCTGCCCCACACCGGGAACCGGCACAACCACTGGGCTGGCCTCTATGGAAGGCTCGAGTGGGACGGCTTCTTCAGCACAACCGTC ACCAACCCCGAGCCCATGGGCAAGCAGGGCCGCGTGCTCCACCCAGAGCAGCACCGTGTGGTGAGCGTGCGGGAGTGTGCCCGCTCCCAG GGCTTCCCTGACACCTACCGGCTCTTCGGCAACATCCTGGACAAGCACCGGCAGGTCCAGAACGTCTCCCAGTCCATGGAGGTCCTTGAG TTGCGGACGTATCGCGACCTCCAGTATGTACGCGGCATGGAGACCCTCATGCGGAGCCTGGATGCGCGGCTCCGGGCAGCTGATGGGTCC CTCTCGGCCAAGAGCTTCCAGGAGCTGAAGGACAGGATGACGGAACTGTTGCCCCTGAGCTCGGTCCTGGAGCAGTACAAGGCAGACACG CGGACCATTGTACGCTTGCGGGAGGAGGTGAGGAATCTCTCCGGCAGTCTGGCGGCCATTCAGGAGGAGATGGGTGCCTACGGGTATGAG GACCTGCAGCAACGGGTGATGGCCCTGGAGGCCCGGCTCCACGCCTGCGCCCAGAAGCTGGGCTGTGGGAAGCTGACCGGGGTCAGTAAC CCCATCACCGTTCGGGCCATGGGGTCCCGCTTCGGCTCCTGGATGACTGACACGATGGCCCCCAGTGCGGATAGCCGGGTCTGGTACATG GATGGCTATTACAAAGGCCGCCGGGTCCTGGAGTTCCGTACCCTGGGAGACTTCATCAAAGGCCAGAACTTTATCCAGCACCTGCTGCCC CAGCCGTGGGCGGGCACGGGCCACGTGGTGTACAACGGCTCCCTGTTCTATAACAAGTACCAGAGCAACGTGGTGGTCAAATACCACTTC CGCTCGCGCTCTGTGCTGGTGCAGAGGAGCCTCCCGGGCGCCGGTTACAACAACACCTTCCCCTACTCCTGGGGCGGCTTCTCCGACATG GACTTCATGGTGGACGAGAGCGGGCTCTGGGCTGTGTACACCACCAACCAGAACGCGGGCAACATCGTGGTCAGCCGGCTGGACCCGCAC ACCCTCGAGGTCATGCGGTCCTGGGACACCGGCTACCCCAAGCGCAGCGCTGGCGAGGCCTTCATGATCTGCGGTGTGCTCTACGTGACC AACTCCCACCTGGCTGGGGCCAAGGTCTACTTCGCCTATTTTACCAACACGTCCAGTTACGAGTACACGGACGTGCCCTTCCACAACCAG TATTCCCACATCTCGATGCTGGATTACAACCCCCGGGAGCGCGCCCTCTATACCTGGAACAACGGCCACCAGGTGCTCTACAATGTCACC >In-frame_DNMT1_ENST00000359526_chr19_10246412_-_OLFM2_ENST00000264833_chr19_9968537_-_5925nt ATGCCGGCGCGTACCGCCCCAGCCCGGGTGCCCACACTGGCCGTCCCGGCCATCTCGCTGCCCGACGATGTCCGCAGGCGGCTCAAAGAT TTGGAAAGAGACAGCTTAACAGAAAAGGAATGTGTGAAGGAGAAATTGAATCTCTTGCACGAATTTCTGCAAACAGAAATAAAGAATCAG TTATGTGACTTGGAAACCAAATTACGTAAAGAAGAATTATCCGAGGAGGGCTACCTGGCTAAAGTCAAATCCCTTTTAAATAAAGATTTG TCCTTGGAGAACGGTGCTCATGCTTACAACCGGGAAGTGAATGGACGTCTAGAAAACGGGAACCAAGCAAGAAGTGAAGCCCGTAGAGTG GGAATGGCAGATGCCAACAGCCCCCCCAAACCCCTTTCCAAACCTCGCACGCCCAGGAGGAGCAAGTCCGATGGAGAGGCTAAGCGTTCA AGAGACCCTCCTGCCTCAGCCTCCCAAGTAACTGGGATTAGAGCTGAACCTTCACCTAGCCCCAGGATTACAAGGAAAAGCACCAGGCAA ACCACCATCACATCTCATTTTGCAAAGGGCCCTGCCAAACGGAAACCTCAGGAAGAGTCTGAAAGAGCCAAATCGGATGAGTCCATCAAG GAAGAAGACAAAGACCAGGATGAGAAGAGACGTAGAGTTACATCCAGAGAACGAGTTGCTAGACCGCTTCCTGCAGAAGAACCTGAAAGA GCAAAATCAGGAACGCGCACTGAAAAGGAAGAAGAAAGAGATGAAAAAGAAGAAAAGAGACTCCGAAGTCAAACCAAAGAACCAACACCC AAACAGAAACTGAAGGAGGAGCCGGACAGAGAAGCCAGGGCAGGCGTGCAGGCTGACGAGGACGAAGATGGAGACGAGAAAGATGAGAAG AAGCACAGAAGTCAACCCAAAGATCTAGCTGCCAAACGGAGGCCCGAAGAAAAAGAACCTGAAAAAGTAAATCCACAGATTTCTGATGAA AAAGACGAGGATGAAAAGGAGGAGAAGAGACGCAAAACGACCCCCAAAGAACCAACGGAGAAAAAAATGGCTCGCGCCAAAACAGTCATG AACTCCAAGACCCACCCTCCCAAGTGCATTCAGTGCGGGCAGTACCTGGACGACCCTGACCTCAAATATGGGCAGCACCCACCAGACGCG GTGGATGAGCCACAGATGCTGACAAATGAGAAGCTGTCCATCTTTGATGCCAACGAGTCTGGCTTTGAGAGTTATGAGGCGCTTCCCCAG CACAAACTGACCTGCTTCAGTGTGTACTGTAAGCACGGTCACCTGTGTCCCATCGACACCGGCCTCATCGAGAAGAATATCGAACTCTTC TTTTCTGGTTCAGCAAAACCAATCTATGATGATGACCCATCTCTTGAAGGTGGTGTTAATGGCAAAAATCTTGGCCCCATAAATGAATGG TGGATCACTGGCTTTGATGGAGGTGAAAAGGCCCTCATCGGCTTCAGCACCTCATTTGCCGAATACATTCTGATGGATCCCAGTCCCGAG TATGCGCCCATATTTGGGCTGATGCAGGAGAAGATCTACATCAGCAAGATTGTGGTGGAGTTCCTGCAGAGCAATTCCGACTCGACCTAT GAGGACCTGATCAACAAGATCGAGACCACGGTTCCTCCTTCTGGCCTCAACTTGAACCGCTTCACAGAGGACTCCCTCCTGCGACACGCG CAGTTTGTGGTGGAGCAGGTGGAGAGTTATGACGAGGCCGGGGACAGTGATGAGCAGCCCATCTTCCTGACACCCTGCATGCGGGACCTG ATCAAGCTGGCTGGGGTCACGCTGGGACAGAGGCGAGCCCAGGCGAGGCGGCAGACCATCAGGCATTCTACCAGGGAGAAGGACAGGGGA CCCACGAAAGCCACCACCACCAAGCTGGTCTACCAGATCTTCGATACTTTCTTCGCAGAGCAAATTGAAAAGGATGACAGAGAAGACAAG GAGAACGCCTTTAAGCGCCGGCGATGTGGCGTCTGTGAGGTGTGTCAGCAGCCTGAGTGTGGGAAATGTAAAGCCTGCAAGGACATGGTT AAATTTGGTGGCAGTGGACGGAGCAAGCAGGCTTGCCAAGAGCGGAGGTGTCCCAATATGGCCATGAAGGAGGCAGATGACGATGAGGAA GTCGATGATAACATCCCAGAGATGCCGTCACCCAAAAAAATGCACCAGGGGAAGAAGAAGAAACAGAACAAGAATCGCATCTCTTGGGTC GGAGAAGCCGTCAAGACTGATGGGAAGAAGAGTTACTATAAGAAGGTGTGCATTGATGCGGAAACCCTGGAAGTGGGGGACTGTGTCTCT GTTATTCCAGATGATTCCTCAAAACCGCTGTATCTAGCAAGGGTCACGGCGCTGTGGGAGGACAGCAGCAACGGGCAGATGTTTCACGCC CACTGGTTCTGCGCTGGGACAGACACAGTCCTCGGGGCCACGTCGGACCCTCTGGAGCTGTTCTTGGTGGATGAATGTGAGGACATGCAG CTTTCATATATCCACAGCAAAGTGAAAGTCATCTACAAAGCCCCCTCCGAAAACTGGGCCATGGAGGGAGGCATGGATCCCGAGTCCCTG CTGGAGGGGGACGACGGGAAGACCTACTTCTACCAGCTGTGGTATGATCAAGACTACGCGAGATTCGAGTCCCCTCCAAAAACCCAGCCA ACAGAGGACAACAAGTTCAAATTCTGTGTGAGCTGTGCCCGTCTGGCTGAGATGAGGCAAAAAGAAATCCCCAGGGTCCTGGAGCAGCTC GAGGACCTGGATAGCCGGGTCCTCTACTACTCAGCCACCAAGAACGGCATCCTGTACCGAGTTGGTGATGGTGTGTACCTGCCCCCTGAG GCCTTCACGTTCAACATCAAGCTGTCCAGTCCCGTGAAACGCCCACGGAAGGAGCCCGTGGATGAGGACCTGTACCCAGAGCACTACCGG AAATACTCCGACTACATCAAAGGCAGCAACCTGGATGCCCCTGAGCCCTACCGAATTGGCCGGATCAAAGAGATCTTCTGTCCCAAGAAG AGCAACGGCAGGCCCAATGAGACTGACATCAAAATCCGGGTCAACAAGTTCTACAGGCCTGAGAACACCCACAAGTCCACTCCAGCGAGC TACCACGCAGACATCAACCTGCTCTACTGGAGCGACGAGGAGGCCGTGGTGGACTTCAAGGCTGTGCAGGGCCGCTGCACCGTGGAGTAT GGGGAGGACCTGCCCGAGTGCGTCCAGGTGTACTCCATGGGCGGCCCCAACCGCTTCTACTTCCTCGAGGCCTATAATGCAAAGAGCAAA AGCTTTGAAGATCCTCCCAACCATGCCCGTAGCCCTGGAAACAAAGGGAAGGGCAAGGGAAAAGGGAAGGGCAAGCCCAAGTCCCAAGCC TGTGAGCCGAGCGAGCCAGAGATAGAGATCAAGCTGCCCAAGCTGCGGACCCTGGATGTGTTTTCTGGCTGCGGGGGGTTGTCGGAGGGA TTCCACCAAGCAGGCATCTCTGACACGCTGTGGGCCATCGAGATGTGGGACCCTGCGGCCCAGGCGTTCCGGCTGAACAACCCCGGCTCC ACAGTGTTCACAGAGGACTGCAACATCCTGCTGAAGCTGGTCATGGCTGGGGAGACCACCAACTCCCGCGGCCAGCGGCTGCCCCAGAAG GGAGACGTGGAGATGCTGTGCGGCGGGCCGCCCTGCCAGGGCTTCAGCGGCATGAACCGCTTCAATTCGCGCACCTACTCCAAGTTCAAA AACTCTCTGGTGGTTTCCTTCCTCAGCTACTGCGACTACTACCGGCCCCGGTTCTTCCTCCTGGAGAATGTCAGGAACTTTGTCTCCTTC AAGCGCTCCATGGTCCTGAAGCTCACCCTCCGCTGCCTGGTCCGCATGGGCTATCAGTGCACCTTCGGCGTGCTGCAGGCCGGTCAGTAC GGCGTGGCCCAGACTAGGAGGCGGGCCATCATCCTGGCCGCGGCCCCTGGAGAGAAGCTCCCTCTGTTCCCGGAGCCACTGCACGTGTTT GCTCCCCGGGCCTGCCAGCTGAGCGTGGTGGTGGATGACAAGAAGTTTGTGAGCAACATAACCAGGTTGAGCTCGGGTCCTTTCCGGACC ATCACGGTGCGAGACACGATGTCCGACCTGCCGGAGGTGCGGAATGGAGCCTCGGCACTGGAGATCTCCTACAACGGGGAGCCTCAGTCC TGGTTCCAGAGGCAGCTCCGGGGCGCACAGTACCAGCCCATCCTCAGGGACCACATCTGTAAGGACATGAGTGCATTGGTGGCTGCCCGC ATGCGGCACATCCCCTTGGCCCCAGGGTCAGACTGGCGCGATCTGCCCAACATCGAGGTGCGGCTCTCAGACGGCACCATGGCCAGGAAG CTGCGGTATACCCACCATGACAGGAAGAACGGCCGCAGCAGCTCTGGGGCCCTCCGTGGGGTCTGCTCCTGCGTGGAAGCCGGCAAAGCC TGCGACCCCGCAGCCAGGCAGTTCAACACCCTCATCCCCTGGTGCCTGCCCCACACCGGGAACCGGCACAACCACTGGGCTGGCCTCTAT GGAAGGCTCGAGTGGGACGGCTTCTTCAGCACAACCGTCACCAACCCCGAGCCCATGGGCAAGCAGGGCCGCGTGCTCCACCCAGAGCAG CACCGTGTGGTGAGCGTGCGGGAGTGTGCCCGCTCCCAGGGCTTCCCTGACACCTACCGGCTCTTCGGCAACATCCTGGACAAGCACCGG CAGGTCCAGAACGTCTCCCAGTCCATGGAGGTCCTTGAGTTGCGGACGTATCGCGACCTCCAGTATGTACGCGGCATGGAGACCCTCATG CGGAGCCTGGATGCGCGGCTCCGGGCAGCTGATGGGTCCCTCTCGGCCAAGAGCTTCCAGGAGCTGAAGGACAGGATGACGGAACTGTTG CCCCTGAGCTCGGTCCTGGAGCAGTACAAGGCAGACACGCGGACCATTGTACGCTTGCGGGAGGAGGTGAGGAATCTCTCCGGCAGTCTG GCGGCCATTCAGGAGGAGATGGGTGCCTACGGGTATGAGGACCTGCAGCAACGGGTGATGGCCCTGGAGGCCCGGCTCCACGCCTGCGCC CAGAAGCTGGGCTGTGGGAAGCTGACCGGGGTCAGTAACCCCATCACCGTTCGGGCCATGGGGTCCCGCTTCGGCTCCTGGATGACTGAC ACGATGGCCCCCAGTGCGGATAGCCGGGTCTGGTACATGGATGGCTATTACAAAGGCCGCCGGGTCCTGGAGTTCCGTACCCTGGGAGAC TTCATCAAAGGCCAGAACTTTATCCAGCACCTGCTGCCCCAGCCGTGGGCGGGCACGGGCCACGTGGTGTACAACGGCTCCCTGTTCTAT AACAAGTACCAGAGCAACGTGGTGGTCAAATACCACTTCCGCTCGCGCTCTGTGCTGGTGCAGAGGAGCCTCCCGGGCGCCGGTTACAAC AACACCTTCCCCTACTCCTGGGGCGGCTTCTCCGACATGGACTTCATGGTGGACGAGAGCGGGCTCTGGGCTGTGTACACCACCAACCAG AACGCGGGCAACATCGTGGTCAGCCGGCTGGACCCGCACACCCTCGAGGTCATGCGGTCCTGGGACACCGGCTACCCCAAGCGCAGCGCT GGCGAGGCCTTCATGATCTGCGGTGTGCTCTACGTGACCAACTCCCACCTGGCTGGGGCCAAGGTCTACTTCGCCTATTTTACCAACACG TCCAGTTACGAGTACACGGACGTGCCCTTCCACAACCAGTATTCCCACATCTCGATGCTGGATTACAACCCCCGGGAGCGCGCCCTCTAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_DNMT1_ENST00000340748_chr19_10246412_-_OLFM2_ENST00000264833_chr19_9968537_-_6581nt TCCGCGTGGGGGGGGTGTGTGCCCGCCTTGCGCATGCGTGTTCCCTGGGCATGGCCGGCTCCGTTCCATCCTTCTGCACAGGGTATCGCC TCTCTCCGTTTGGTACATCCCCTCCTCCCCCACGCCCGGACTGGGGTGGTAGACGCCGCCTCCGCTCATCGCCCCTCCCCATCGGTTTCC GCGCGAAAAGCCGGGGCGCCTGCGCTGCCGCCGCCGCGTCTGCTGAAGCCTCCGAGATGCCGGCGCGTACCGCCCCAGCCCGGGTGCCCA CACTGGCCGTCCCGGCCATCTCGCTGCCCGACGATGTCCGCAGGCGGCTCAAAGATTTGGAAAGAGACAGCTTAACAGAAAAGGAATGTG TGAAGGAGAAATTGAATCTCTTGCACGAATTTCTGCAAACAGAAATAAAGAATCAGTTATGTGACTTGGAAACCAAATTACGTAAAGAAG AATTATCCGAGGAGGGCTACCTGGCTAAAGTCAAATCCCTTTTAAATAAAGATTTGTCCTTGGAGAACGGTGCTCATGCTTACAACCGGG AAGTGAATGGACGTCTAGAAAACGGGAACCAAGCAAGAAGTGAAGCCCGTAGAGTGGGAATGGCAGATGCCAACAGCCCCCCCAAACCCC TTTCCAAACCTCGCACGCCCAGGAGGAGCAAGTCCGATGGAGAGGCTAAGCCTGAACCTTCACCTAGCCCCAGGATTACAAGGAAAAGCA CCAGGCAAACCACCATCACATCTCATTTTGCAAAGGGCCCTGCCAAACGGAAACCTCAGGAAGAGTCTGAAAGAGCCAAATCGGATGAGT CCATCAAGGAAGAAGACAAAGACCAGGATGAGAAGAGACGTAGAGTTACATCCAGAGAACGAGTTGCTAGACCGCTTCCTGCAGAAGAAC CTGAAAGAGCAAAATCAGGAACGCGCACTGAAAAGGAAGAAGAAAGAGATGAAAAAGAAGAAAAGAGACTCCGAAGTCAAACCAAAGAAC CAACACCCAAACAGAAACTGAAGGAGGAGCCGGACAGAGAAGCCAGGGCAGGCGTGCAGGCTGACGAGGACGAAGATGGAGACGAGAAAG ATGAGAAGAAGCACAGAAGTCAACCCAAAGATCTAGCTGCCAAACGGAGGCCCGAAGAAAAAGAACCTGAAAAAGTAAATCCACAGATTT CTGATGAAAAAGACGAGGATGAAAAGGAGGAGAAGAGACGCAAAACGACCCCCAAAGAACCAACGGAGAAAAAAATGGCTCGCGCCAAAA CAGTCATGAACTCCAAGACCCACCCTCCCAAGTGCATTCAGTGCGGGCAGTACCTGGACGACCCTGACCTCAAATATGGGCAGCACCCAC CAGACGCGGTGGATGAGCCACAGATGCTGACAAATGAGAAGCTGTCCATCTTTGATGCCAACGAGTCTGGCTTTGAGAGTTATGAGGCGC TTCCCCAGCACAAACTGACCTGCTTCAGTGTGTACTGTAAGCACGGTCACCTGTGTCCCATCGACACCGGCCTCATCGAGAAGAATATCG AACTCTTCTTTTCTGGTTCAGCAAAACCAATCTATGATGATGACCCATCTCTTGAAGGTGGTGTTAATGGCAAAAATCTTGGCCCCATAA ATGAATGGTGGATCACTGGCTTTGATGGAGGTGAAAAGGCCCTCATCGGCTTCAGCACCTCATTTGCCGAATACATTCTGATGGATCCCA GTCCCGAGTATGCGCCCATATTTGGGCTGATGCAGGAGAAGATCTACATCAGCAAGATTGTGGTGGAGTTCCTGCAGAGCAATTCCGACT CGACCTATGAGGACCTGATCAACAAGATCGAGACCACGGTTCCTCCTTCTGGCCTCAACTTGAACCGCTTCACAGAGGACTCCCTCCTGC GACACGCGCAGTTTGTGGTGGAGCAGGTGGAGAGTTATGACGAGGCCGGGGACAGTGATGAGCAGCCCATCTTCCTGACACCCTGCATGC GGGACCTGATCAAGCTGGCTGGGGTCACGCTGGGACAGAGGCGAGCCCAGGCGAGGCGGCAGACCATCAGGCATTCTACCAGGGAGAAGG ACAGGGGACCCACGAAAGCCACCACCACCAAGCTGGTCTACCAGATCTTCGATACTTTCTTCGCAGAGCAAATTGAAAAGGATGACAGAG AAGACAAGGAGAACGCCTTTAAGCGCCGGCGATGTGGCGTCTGTGAGGTGTGTCAGCAGCCTGAGTGTGGGAAATGTAAAGCCTGCAAGG ACATGGTTAAATTTGGTGGCAGTGGACGGAGCAAGCAGGCTTGCCAAGAGCGGAGGTGTCCCAATATGGCCATGAAGGAGGCAGATGACG ATGAGGAAGTCGATGATAACATCCCAGAGATGCCGTCACCCAAAAAAATGCACCAGGGGAAGAAGAAGAAACAGAACAAGAATCGCATCT CTTGGGTCGGAGAAGCCGTCAAGACTGATGGGAAGAAGAGTTACTATAAGAAGGTGTGCATTGATGCGGAAACCCTGGAAGTGGGGGACT GTGTCTCTGTTATTCCAGATGATTCCTCAAAACCGCTGTATCTAGCAAGGGTCACGGCGCTGTGGGAGGACAGCAGCAACGGGCAGATGT TTCACGCCCACTGGTTCTGCGCTGGGACAGACACAGTCCTCGGGGCCACGTCGGACCCTCTGGAGCTGTTCTTGGTGGATGAATGTGAGG ACATGCAGCTTTCATATATCCACAGCAAAGTGAAAGTCATCTACAAAGCCCCCTCCGAAAACTGGGCCATGGAGGGAGGCATGGATCCCG AGTCCCTGCTGGAGGGGGACGACGGGAAGACCTACTTCTACCAGCTGTGGTATGATCAAGACTACGCGAGATTCGAGTCCCCTCCAAAAA CCCAGCCAACAGAGGACAACAAGTTCAAATTCTGTGTGAGCTGTGCCCGTCTGGCTGAGATGAGGCAAAAAGAAATCCCCAGGGTCCTGG AGCAGCTCGAGGACCTGGATAGCCGGGTCCTCTACTACTCAGCCACCAAGAACGGCATCCTGTACCGAGTTGGTGATGGTGTGTACCTGC CCCCTGAGGCCTTCACGTTCAACATCAAGCTGTCCAGTCCCGTGAAACGCCCACGGAAGGAGCCCGTGGATGAGGACCTGTACCCAGAGC ACTACCGGAAATACTCCGACTACATCAAAGGCAGCAACCTGGATGCCCCTGAGCCCTACCGAATTGGCCGGATCAAAGAGATCTTCTGTC CCAAGAAGAGCAACGGCAGGCCCAATGAGACTGACATCAAAATCCGGGTCAACAAGTTCTACAGGCCTGAGAACACCCACAAGTCCACTC CAGCGAGCTACCACGCAGACATCAACCTGCTCTACTGGAGCGACGAGGAGGCCGTGGTGGACTTCAAGGCTGTGCAGGGCCGCTGCACCG TGGAGTATGGGGAGGACCTGCCCGAGTGCGTCCAGGTGTACTCCATGGGCGGCCCCAACCGCTTCTACTTCCTCGAGGCCTATAATGCAA AGAGCAAAAGCTTTGAAGATCCTCCCAACCATGCCCGTAGCCCTGGAAACAAAGGGAAGGGCAAGGGAAAAGGGAAGGGCAAGCCCAAGT CCCAAGCCTGTGAGCCGAGCGAGCCAGAGATAGAGATCAAGCTGCCCAAGCTGCGGACCCTGGATGTGTTTTCTGGCTGCGGGGGGTTGT CGGAGGGATTCCACCAAGCAGGCATCTCTGACACGCTGTGGGCCATCGAGATGTGGGACCCTGCGGCCCAGGCGTTCCGGCTGAACAACC CCGGCTCCACAGTGTTCACAGAGGACTGCAACATCCTGCTGAAGCTGGTCATGGCTGGGGAGACCACCAACTCCCGCGGCCAGCGGCTGC CCCAGAAGGGAGACGTGGAGATGCTGTGCGGCGGGCCGCCCTGCCAGGGCTTCAGCGGCATGAACCGCTTCAATTCGCGCACCTACTCCA AGTTCAAAAACTCTCTGGTGGTTTCCTTCCTCAGCTACTGCGACTACTACCGGCCCCGGTTCTTCCTCCTGGAGAATGTCAGGAACTTTG TCTCCTTCAAGCGCTCCATGGTCCTGAAGCTCACCCTCCGCTGCCTGGTCCGCATGGGCTATCAGTGCACCTTCGGCGTGCTGCAGGCCG GTCAGTACGGCGTGGCCCAGACTAGGAGGCGGGCCATCATCCTGGCCGCGGCCCCTGGAGAGAAGCTCCCTCTGTTCCCGGAGCCACTGC ACGTGTTTGCTCCCCGGGCCTGCCAGCTGAGCGTGGTGGTGGATGACAAGAAGTTTGTGAGCAACATAACCAGGTTGAGCTCGGGTCCTT TCCGGACCATCACGGTGCGAGACACGATGTCCGACCTGCCGGAGGTGCGGAATGGAGCCTCGGCACTGGAGATCTCCTACAACGGGGAGC CTCAGTCCTGGTTCCAGAGGCAGCTCCGGGGCGCACAGTACCAGCCCATCCTCAGGGACCACATCTGTAAGGACATGAGTGCATTGGTGG CTGCCCGCATGCGGCACATCCCCTTGGCCCCAGGGTCAGACTGGCGCGATCTGCCCAACATCGAGGTGCGGCTCTCAGACGGCACCATGG CCAGGAAGCTGCGGTATACCCACCATGACAGGAAGAACGGCCGCAGCAGCTCTGGGGCCCTCCGTGGGGTCTGCTCCTGCGTGGAAGCCG GCAAAGCCTGCGACCCCGCAGCCAGGCAGTTCAACACCCTCATCCCCTGGTGCCTGCCCCACACCGGGAACCGGCACAACCACTGGGCTG GCCTCTATGGAAGGCTCGAGTGGGACGGCTTCTTCAGCACAACCGTCACCAACCCCGAGCCCATGGGCAAGCAGGGCCGCGTGCTCCACC CAGAGCAGCACCGTGTGGTGAGCGTGCGGGAGTGTGCCCGCTCCCAGGGCTTCCCTGACACCTACCGGCTCTTCGGCAACATCCTGGACA AGCACCGGCAGGTCCAGAACGTCTCCCAGTCCATGGAGGTCCTTGAGTTGCGGACGTATCGCGACCTCCAGTATGTACGCGGCATGGAGA CCCTCATGCGGAGCCTGGATGCGCGGCTCCGGGCAGCTGATGGGTCCCTCTCGGCCAAGAGCTTCCAGGAGCTGAAGGACAGGATGACGG AACTGTTGCCCCTGAGCTCGGTCCTGGAGCAGTACAAGGCAGACACGCGGACCATTGTACGCTTGCGGGAGGAGGTGAGGAATCTCTCCG GCAGTCTGGCGGCCATTCAGGAGGAGATGGGTGCCTACGGGTATGAGGACCTGCAGCAACGGGTGATGGCCCTGGAGGCCCGGCTCCACG CCTGCGCCCAGAAGCTGGGCTGTGGGAAGCTGACCGGGGTCAGTAACCCCATCACCGTTCGGGCCATGGGGTCCCGCTTCGGCTCCTGGA TGACTGACACGATGGCCCCCAGTGCGGATAGCCGGGTCTGGTACATGGATGGCTATTACAAAGGCCGCCGGGTCCTGGAGTTCCGTACCC TGGGAGACTTCATCAAAGGCCAGAACTTTATCCAGCACCTGCTGCCCCAGCCGTGGGCGGGCACGGGCCACGTGGTGTACAACGGCTCCC TGTTCTATAACAAGTACCAGAGCAACGTGGTGGTCAAATACCACTTCCGCTCGCGCTCTGTGCTGGTGCAGAGGAGCCTCCCGGGCGCCG GTTACAACAACACCTTCCCCTACTCCTGGGGCGGCTTCTCCGACATGGACTTCATGGTGGACGAGAGCGGGCTCTGGGCTGTGTACACCA CCAACCAGAACGCGGGCAACATCGTGGTCAGCCGGCTGGACCCGCACACCCTCGAGGTCATGCGGTCCTGGGACACCGGCTACCCCAAGC GCAGCGCTGGCGAGGCCTTCATGATCTGCGGTGTGCTCTACGTGACCAACTCCCACCTGGCTGGGGCCAAGGTCTACTTCGCCTATTTTA CCAACACGTCCAGTTACGAGTACACGGACGTGCCCTTCCACAACCAGTATTCCCACATCTCGATGCTGGATTACAACCCCCGGGAGCGCG CCCTCTATACCTGGAACAACGGCCACCAGGTGCTCTACAATGTCACCCTGTTTCACGTCATCAGCACCTCTGGGGACCCCTGAGCCAATG CTGTGGCTCGGGCTGCTGCCTGGGGGGCCTCTGGGGGCTGGGGGCCCTTTTCATTCTGCCTGTGTCCCTCAAGGGTGATCTCTCTGTCTC TGTCACGCCCTTTCTCCCCGCCTTTTTGCTGGGCTTTTGTTCTCTGCCTATGTATTTCTGTCTATTTTTTCAATTTCCCCTCTTCTCCTT TATTGATCTCTGCTTTTAATACACCACTTCTTTCTTTCTGCCTTTTTATGGATGTCTTTTTCTTTTTATGGCTCTGGTTCTCCAGTTCTT TCCGTCTCTGCCTCTCTCTGTCTCTCTCTCTCTGTCCTTCCACCCCTCCCTCCTTGCTTCCCACCCATTCCTCATCCCTCACTCCCACCC CCACCCCCACCCCCAGGAGTTGAGTGCATGGATCTGTTTCTTTTTTTATTTACACTTTTTCTTTCCGGTTTGCCGGAATAAACAGGACCT >In-frame_DNMT1_ENST00000540357_chr19_10246412_-_OLFM2_ENST00000264833_chr19_9968537_-_6534nt GGCTCCGTTCCATCCTTCTGCACAGGGTATCGCCTCTCTCCGTTTGGTACATCCCCTCCTCCCCCACGCCCGGACTGGGGTGGTAGACGC CGCCTCCGCTCATCGCCCCTCCCCATCGGTTTCCGCGCGAAAAGCCGGGGCGCCTGCGCTGCCGCCGCCGCGTCTGCTGAAGCCTCCGAG ATGCCGGCGCGTACCGCCCCAGCCCGGGTGCCCACACTGGCCGTCCCGGCCATCTCGCTGCCCGACGATGTCCGCAGGCGGCTCAAAGAT TTGGAAAGAGACAGCTTAACAGAAAAGGAATGTGTGAAGGAGAAATTGAATCTCTTGCACGAATTTCTGCAAACAGAAATAAAGAATCAG TTATGTGACTTGGAAACCAAATTACGTAAAGAAGAATTATCCGAGGAGGGCTACCTGGCTAAAGTCAAATCCCTTTTAAATAAAGATTTG TCCTTGGAGAACGGTGCTCATGCTTACAACCGGGAAGTGAATGGACGTCTAGAAAACGGGAACCAAGCAAGAAGTGAAGCCCGTAGAGTG GGAATGGCAGATGCCAACAGCCCCCCCAAACCCCTTTCCAAACCTCGCACGCCCAGGAGGAGCAAGTCCGATGGAGAGGCTAAGCCTGAA CCTTCACCTAGCCCCAGGATTACAAGGAAAAGCACCAGGCAAACCACCATCACATCTCATTTTGCAAAGGGCCCTGCCAAACGGAAACCT CAGGAAGAGTCTGAAAGAGCCAAATCGGATGAGTCCATCAAGGAAGAAGACAAAGACCAGGATGAGAAGAGACGTAGAGTTACATCCAGA GAACGAGTTGCTAGACCGCTTCCTGCAGAAGAACCTGAAAGAGCAAAATCAGGAACGCGCACTGAAAAGGAAGAAGAAAGAGATGAAAAA GAAGAAAAGAGACTCCGAAGTCAAACCAAAGAACCAACACCCAAACAGAAACTGAAGGAGGAGCCGGACAGAGAAGCCAGGGCAGGCGTG CAGGCTGACGAGGACGAAGATGGAGACGAGAAAGATGAGAAGAAGCACAGAAGTCAACCCAAAGATCTAGCTGCCAAACGGAGGCCCGAA GAAAAAGAACCTGAAAAAGTAAATCCACAGATTTCTGATGAAAAAGACGAGGATGAAAAGGAGGAGAAGAGACGCAAAACGACCCCCAAA GAACCAACGGAGAAAAAAATGGCTCGCGCCAAAACAGTCATGAACTCCAAGACCCACCCTCCCAAGTGCATTCAGTGCGGGCAGTACCTG GACGACCCTGACCTCAAATATGGGCAGCACCCACCAGACGCGGTGGATGAGCCACAGATGCTGACAAATGAGAAGCTGTCCATCTTTGAT GCCAACGAGTCTGGCTTTGAGAGTTATGAGGCGCTTCCCCAGCACAAACTGACCTGCTTCAGTGTGTACTGTAAGCACGGTCACCTGTGT CCCATCGACACCGGCCTCATCGAGAAGAATATCGAACTCTTCTTTTCTGGTTCAGCAAAACCAATCTATGATGATGACCCATCTCTTGAA GGTGGTGTTAATGGCAAAAATCTTGGCCCCATAAATGAATGGTGGATCACTGGCTTTGATGGAGGTGAAAAGGCCCTCATCGGCTTCAGC ACCTCATTTGCCGAATACATTCTGATGGATCCCAGTCCCGAGTATGCGCCCATATTTGGGCTGATGCAGGAGAAGATCTACATCAGCAAG ATTGTGGTGGAGTTCCTGCAGAGCAATTCCGACTCGACCTATGAGGACCTGATCAACAAGATCGAGACCACGGTTCCTCCTTCTGGCCTC AACTTGAACCGCTTCACAGAGGACTCCCTCCTGCGACACGCGCAGTTTGTGGTGGAGCAGGTGGAGAGTTATGACGAGGCCGGGGACAGT GATGAGCAGCCCATCTTCCTGACACCCTGCATGCGGGACCTGATCAAGCTGGCTGGGGTCACGCTGGGACAGAGGCGAGCCCAGGCGAGG CGGCAGACCATCAGGCATTCTACCAGGGAGAAGGACAGGGGACCCACGAAAGCCACCACCACCAAGCTGGTCTACCAGATCTTCGATACT TTCTTCGCAGAGCAAATTGAAAAGGATGACAGAGAAGACAAGGAGAACGCCTTTAAGCGCCGGCGATGTGGCGTCTGTGAGGTGTGTCAG CAGCCTGAGTGTGGGAAATGTAAAGCCTGCAAGGACATGGTTAAATTTGGTGGCAGTGGACGGAGCAAGCAGGCTTGCCAAGAGCGGAGG TGTCCCAATATGGCCATGAAGGAGGCAGATGACGATGAGGAAGTCGATGATAACATCCCAGAGATGCCGTCACCCAAAAAAATGCACCAG GGGAAGAAGAAGAAACAGAACAAGAATCGCATCTCTTGGGTCGGAGAAGCCGTCAAGACTGATGGGAAGAAGAGTTACTATAAGAAGGTG TGCATTGATGCGGAAACCCTGGAAGTGGGGGACTGTGTCTCTGTTATTCCAGATGATTCCTCAAAACCGCTGTATCTAGCAAGGGTCACG GCGCTGTGGGAGGACAGCAGCAACGGGCAGATGTTTCACGCCCACTGGTTCTGCGCTGGGACAGACACAGTCCTCGGGGCCACGTCGGAC CCTCTGGAGCTGTTCTTGGTGGATGAATGTGAGGACATGCAGCTTTCATATATCCACAGCAAAGTGAAAGTCATCTACAAAGCCCCCTCC GAAAACTGGGCCATGGAGGGAGGCATGGATCCCGAGTCCCTGCTGGAGGGGGACGACGGGAAGACCTACTTCTACCAGCTGTGGTATGAT CAAGACTACGCGAGATTCGAGTCCCCTCCAAAAACCCAGCCAACAGAGGACAACAAGTTCAAATTCTGTGTGAGCTGTGCCCGTCTGGCT GAGATGAGGCAAAAAGAAATCCCCAGGGTCCTGGAGCAGCTCGAGGACCTGGATAGCCGGGTCCTCTACTACTCAGCCACCAAGAACGGC ATCCTGTACCGAGTTGGTGATGGTGTGTACCTGCCCCCTGAGGCCTTCACGTTCAACATCAAGCTGTCCAGTCCCGTGAAACGCCCACGG AAGGAGCCCGTGGATGAGGACCTGTACCCAGAGCACTACCGGAAATACTCCGACTACATCAAAGGCAGCAACCTGGATGCCCCTGAGCCC TACCGAATTGGCCGGATCAAAGAGATCTTCTGTCCCAAGAAGAGCAACGGCAGGCCCAATGAGACTGACATCAAAATCCGGGTCAACAAG TTCTACAGGCCTGAGAACACCCACAAGTCCACTCCAGCGAGCTACCACGCAGACATCAACCTGCTCTACTGGAGCGACGAGGAGGCCGTG GTGGACTTCAAGGCTGTGCAGGGCCGCTGCACCGTGGAGTATGGGGAGGACCTGCCCGAGTGCGTCCAGGTGTACTCCATGGGCGGCCCC AACCGCTTCTACTTCCTCGAGGCCTATAATGCAAAGAGCAAAAGCTTTGAAGATCCTCCCAACCATGCCCGTAGCCCTGGAAACAAAGGG AAGGGCAAGGGAAAAGGGAAGGGCAAGCCCAAGTCCCAAGCCTGTGAGCCGAGCGAGCCAGAGATAGAGATCAAGCTGCCCAAGCTGCGG ACCCTGGATGTGTTTTCTGGCTGCGGGGGGTTGTCGGAGGGATTCCACCAAGCAGGCATCTCTGACACGCTGTGGGCCATCGAGATGTGG GACCCTGCGGCCCAGGCGTTCCGGCTGAACAACCCCGGCTCCACAGTGTTCACAGAGGACTGCAACATCCTGCTGAAGCTGGTCATGGCT GGGGAGACCACCAACTCCCGCGGCCAGCGGCTGCCCCAGAAGGGAGACGTGGAGATGCTGTGCGGCGGGCCGCCCTGCCAGGGCTTCAGC GGCATGAACCGCTTCAATTCGCGCACCTACTCCAAGTTCAAAAACTCTCTGGTGGTTTCCTTCCTCAGCTACTGCGACTACTACCGGCCC CGGTTCTTCCTCCTGGAGAATGTCAGGAACTTTGTCTCCTTCAAGCGCTCCATGGTCCTGAAGCTCACCCTCCGCTGCCTGGTCCGCATG GGCTATCAGTGCACCTTCGGCGTGCTGCAGGCCGGTCAGTACGGCGTGGCCCAGACTAGGAGGCGGGCCATCATCCTGGCCGCGGCCCCT GGAGAGAAGCTCCCTCTGTTCCCGGAGCCACTGCACGTGTTTGCTCCCCGGGCCTGCCAGCTGAGCGTGGTGGTGGATGACAAGAAGTTT GTGAGCAACATAACCAGGTTGAGCTCGGGTCCTTTCCGGACCATCACGGTGCGAGACACGATGTCCGACCTGCCGGAGGTGCGGAATGGA GCCTCGGCACTGGAGATCTCCTACAACGGGGAGCCTCAGTCCTGGTTCCAGAGGCAGCTCCGGGGCGCACAGTACCAGCCCATCCTCAGG GACCACATCTGTAAGGACATGAGTGCATTGGTGGCTGCCCGCATGCGGCACATCCCCTTGGCCCCAGGGTCAGACTGGCGCGATCTGCCC AACATCGAGGTGCGGCTCTCAGACGGCACCATGGCCAGGAAGCTGCGGTATACCCACCATGACAGGAAGAACGGCCGCAGCAGCTCTGGG GCCCTCCGTGGGGTCTGCTCCTGCGTGGAAGGTGGGTCCTCCGGCAAAGCCTGCGACCCCGCAGCCAGGCAGTTCAACACCCTCATCCCC TGGTGCCTGCCCCACACCGGGAACCGGCACAACCACTGGGCTGGCCTCTATGGAAGGCTCGAGTGGGACGGCTTCTTCAGCACAACCGTC ACCAACCCCGAGCCCATGGGCAAGCAGGGCCGCGTGCTCCACCCAGAGCAGCACCGTGTGGTGAGCGTGCGGGAGTGTGCCCGCTCCCAG GGCTTCCCTGACACCTACCGGCTCTTCGGCAACATCCTGGACAAGCACCGGCAGGTCCAGAACGTCTCCCAGTCCATGGAGGTCCTTGAG TTGCGGACGTATCGCGACCTCCAGTATGTACGCGGCATGGAGACCCTCATGCGGAGCCTGGATGCGCGGCTCCGGGCAGCTGATGGGTCC CTCTCGGCCAAGAGCTTCCAGGAGCTGAAGGACAGGATGACGGAACTGTTGCCCCTGAGCTCGGTCCTGGAGCAGTACAAGGCAGACACG CGGACCATTGTACGCTTGCGGGAGGAGGTGAGGAATCTCTCCGGCAGTCTGGCGGCCATTCAGGAGGAGATGGGTGCCTACGGGTATGAG GACCTGCAGCAACGGGTGATGGCCCTGGAGGCCCGGCTCCACGCCTGCGCCCAGAAGCTGGGCTGTGGGAAGCTGACCGGGGTCAGTAAC CCCATCACCGTTCGGGCCATGGGGTCCCGCTTCGGCTCCTGGATGACTGACACGATGGCCCCCAGTGCGGATAGCCGGGTCTGGTACATG GATGGCTATTACAAAGGCCGCCGGGTCCTGGAGTTCCGTACCCTGGGAGACTTCATCAAAGGCCAGAACTTTATCCAGCACCTGCTGCCC CAGCCGTGGGCGGGCACGGGCCACGTGGTGTACAACGGCTCCCTGTTCTATAACAAGTACCAGAGCAACGTGGTGGTCAAATACCACTTC CGCTCGCGCTCTGTGCTGGTGCAGAGGAGCCTCCCGGGCGCCGGTTACAACAACACCTTCCCCTACTCCTGGGGCGGCTTCTCCGACATG GACTTCATGGTGGACGAGAGCGGGCTCTGGGCTGTGTACACCACCAACCAGAACGCGGGCAACATCGTGGTCAGCCGGCTGGACCCGCAC ACCCTCGAGGTCATGCGGTCCTGGGACACCGGCTACCCCAAGCGCAGCGCTGGCGAGGCCTTCATGATCTGCGGTGTGCTCTACGTGACC AACTCCCACCTGGCTGGGGCCAAGGTCTACTTCGCCTATTTTACCAACACGTCCAGTTACGAGTACACGGACGTGCCCTTCCACAACCAG TATTCCCACATCTCGATGCTGGATTACAACCCCCGGGAGCGCGCCCTCTATACCTGGAACAACGGCCACCAGGTGCTCTACAATGTCACC CTGTTTCACGTCATCAGCACCTCTGGGGACCCCTGAGCCAATGCTGTGGCTCGGGCTGCTGCCTGGGGGGCCTCTGGGGGCTGGGGGCCC TTTTCATTCTGCCTGTGTCCCTCAAGGGTGATCTCTCTGTCTCTGTCACGCCCTTTCTCCCCGCCTTTTTGCTGGGCTTTTGTTCTCTGC CTATGTATTTCTGTCTATTTTTTCAATTTCCCCTCTTCTCCTTTATTGATCTCTGCTTTTAATACACCACTTCTTTCTTTCTGCCTTTTT ATGGATGTCTTTTTCTTTTTATGGCTCTGGTTCTCCAGTTCTTTCCGTCTCTGCCTCTCTCTGTCTCTCTCTCTCTGTCCTTCCACCCCT CCCTCCTTGCTTCCCACCCATTCCTCATCCCTCACTCCCACCCCCACCCCCACCCCCAGGAGTTGAGTGCATGGATCTGTTTCTTTTTTT >In-frame_DNMT1_ENST00000359526_chr19_10246412_-_OLFM2_ENST00000264833_chr19_9968537_-_6573nt GGCTCCGTTCCATCCTTCTGCACAGGGTATCGCCTCTCTCCGTTTGGTACATCCCCTCCTCCCCCACGCCCGGACTGGGGTGGTAGACGC CGCCTCCGCTCATCGCCCCTCCCCATCGGTTTCCGCGCGAAAAGCCGGGGCGCCTGCGCTGCCGCCGCCGCGTCTGCTGAAGCCTCCGAG ATGCCGGCGCGTACCGCCCCAGCCCGGGTGCCCACACTGGCCGTCCCGGCCATCTCGCTGCCCGACGATGTCCGCAGGCGGCTCAAAGAT TTGGAAAGAGACAGCTTAACAGAAAAGGAATGTGTGAAGGAGAAATTGAATCTCTTGCACGAATTTCTGCAAACAGAAATAAAGAATCAG TTATGTGACTTGGAAACCAAATTACGTAAAGAAGAATTATCCGAGGAGGGCTACCTGGCTAAAGTCAAATCCCTTTTAAATAAAGATTTG TCCTTGGAGAACGGTGCTCATGCTTACAACCGGGAAGTGAATGGACGTCTAGAAAACGGGAACCAAGCAAGAAGTGAAGCCCGTAGAGTG GGAATGGCAGATGCCAACAGCCCCCCCAAACCCCTTTCCAAACCTCGCACGCCCAGGAGGAGCAAGTCCGATGGAGAGGCTAAGCGTTCA AGAGACCCTCCTGCCTCAGCCTCCCAAGTAACTGGGATTAGAGCTGAACCTTCACCTAGCCCCAGGATTACAAGGAAAAGCACCAGGCAA ACCACCATCACATCTCATTTTGCAAAGGGCCCTGCCAAACGGAAACCTCAGGAAGAGTCTGAAAGAGCCAAATCGGATGAGTCCATCAAG GAAGAAGACAAAGACCAGGATGAGAAGAGACGTAGAGTTACATCCAGAGAACGAGTTGCTAGACCGCTTCCTGCAGAAGAACCTGAAAGA GCAAAATCAGGAACGCGCACTGAAAAGGAAGAAGAAAGAGATGAAAAAGAAGAAAAGAGACTCCGAAGTCAAACCAAAGAACCAACACCC AAACAGAAACTGAAGGAGGAGCCGGACAGAGAAGCCAGGGCAGGCGTGCAGGCTGACGAGGACGAAGATGGAGACGAGAAAGATGAGAAG AAGCACAGAAGTCAACCCAAAGATCTAGCTGCCAAACGGAGGCCCGAAGAAAAAGAACCTGAAAAAGTAAATCCACAGATTTCTGATGAA AAAGACGAGGATGAAAAGGAGGAGAAGAGACGCAAAACGACCCCCAAAGAACCAACGGAGAAAAAAATGGCTCGCGCCAAAACAGTCATG AACTCCAAGACCCACCCTCCCAAGTGCATTCAGTGCGGGCAGTACCTGGACGACCCTGACCTCAAATATGGGCAGCACCCACCAGACGCG GTGGATGAGCCACAGATGCTGACAAATGAGAAGCTGTCCATCTTTGATGCCAACGAGTCTGGCTTTGAGAGTTATGAGGCGCTTCCCCAG CACAAACTGACCTGCTTCAGTGTGTACTGTAAGCACGGTCACCTGTGTCCCATCGACACCGGCCTCATCGAGAAGAATATCGAACTCTTC TTTTCTGGTTCAGCAAAACCAATCTATGATGATGACCCATCTCTTGAAGGTGGTGTTAATGGCAAAAATCTTGGCCCCATAAATGAATGG TGGATCACTGGCTTTGATGGAGGTGAAAAGGCCCTCATCGGCTTCAGCACCTCATTTGCCGAATACATTCTGATGGATCCCAGTCCCGAG TATGCGCCCATATTTGGGCTGATGCAGGAGAAGATCTACATCAGCAAGATTGTGGTGGAGTTCCTGCAGAGCAATTCCGACTCGACCTAT GAGGACCTGATCAACAAGATCGAGACCACGGTTCCTCCTTCTGGCCTCAACTTGAACCGCTTCACAGAGGACTCCCTCCTGCGACACGCG CAGTTTGTGGTGGAGCAGGTGGAGAGTTATGACGAGGCCGGGGACAGTGATGAGCAGCCCATCTTCCTGACACCCTGCATGCGGGACCTG ATCAAGCTGGCTGGGGTCACGCTGGGACAGAGGCGAGCCCAGGCGAGGCGGCAGACCATCAGGCATTCTACCAGGGAGAAGGACAGGGGA CCCACGAAAGCCACCACCACCAAGCTGGTCTACCAGATCTTCGATACTTTCTTCGCAGAGCAAATTGAAAAGGATGACAGAGAAGACAAG GAGAACGCCTTTAAGCGCCGGCGATGTGGCGTCTGTGAGGTGTGTCAGCAGCCTGAGTGTGGGAAATGTAAAGCCTGCAAGGACATGGTT AAATTTGGTGGCAGTGGACGGAGCAAGCAGGCTTGCCAAGAGCGGAGGTGTCCCAATATGGCCATGAAGGAGGCAGATGACGATGAGGAA GTCGATGATAACATCCCAGAGATGCCGTCACCCAAAAAAATGCACCAGGGGAAGAAGAAGAAACAGAACAAGAATCGCATCTCTTGGGTC GGAGAAGCCGTCAAGACTGATGGGAAGAAGAGTTACTATAAGAAGGTGTGCATTGATGCGGAAACCCTGGAAGTGGGGGACTGTGTCTCT GTTATTCCAGATGATTCCTCAAAACCGCTGTATCTAGCAAGGGTCACGGCGCTGTGGGAGGACAGCAGCAACGGGCAGATGTTTCACGCC CACTGGTTCTGCGCTGGGACAGACACAGTCCTCGGGGCCACGTCGGACCCTCTGGAGCTGTTCTTGGTGGATGAATGTGAGGACATGCAG CTTTCATATATCCACAGCAAAGTGAAAGTCATCTACAAAGCCCCCTCCGAAAACTGGGCCATGGAGGGAGGCATGGATCCCGAGTCCCTG CTGGAGGGGGACGACGGGAAGACCTACTTCTACCAGCTGTGGTATGATCAAGACTACGCGAGATTCGAGTCCCCTCCAAAAACCCAGCCA ACAGAGGACAACAAGTTCAAATTCTGTGTGAGCTGTGCCCGTCTGGCTGAGATGAGGCAAAAAGAAATCCCCAGGGTCCTGGAGCAGCTC GAGGACCTGGATAGCCGGGTCCTCTACTACTCAGCCACCAAGAACGGCATCCTGTACCGAGTTGGTGATGGTGTGTACCTGCCCCCTGAG GCCTTCACGTTCAACATCAAGCTGTCCAGTCCCGTGAAACGCCCACGGAAGGAGCCCGTGGATGAGGACCTGTACCCAGAGCACTACCGG AAATACTCCGACTACATCAAAGGCAGCAACCTGGATGCCCCTGAGCCCTACCGAATTGGCCGGATCAAAGAGATCTTCTGTCCCAAGAAG AGCAACGGCAGGCCCAATGAGACTGACATCAAAATCCGGGTCAACAAGTTCTACAGGCCTGAGAACACCCACAAGTCCACTCCAGCGAGC TACCACGCAGACATCAACCTGCTCTACTGGAGCGACGAGGAGGCCGTGGTGGACTTCAAGGCTGTGCAGGGCCGCTGCACCGTGGAGTAT GGGGAGGACCTGCCCGAGTGCGTCCAGGTGTACTCCATGGGCGGCCCCAACCGCTTCTACTTCCTCGAGGCCTATAATGCAAAGAGCAAA AGCTTTGAAGATCCTCCCAACCATGCCCGTAGCCCTGGAAACAAAGGGAAGGGCAAGGGAAAAGGGAAGGGCAAGCCCAAGTCCCAAGCC TGTGAGCCGAGCGAGCCAGAGATAGAGATCAAGCTGCCCAAGCTGCGGACCCTGGATGTGTTTTCTGGCTGCGGGGGGTTGTCGGAGGGA TTCCACCAAGCAGGCATCTCTGACACGCTGTGGGCCATCGAGATGTGGGACCCTGCGGCCCAGGCGTTCCGGCTGAACAACCCCGGCTCC ACAGTGTTCACAGAGGACTGCAACATCCTGCTGAAGCTGGTCATGGCTGGGGAGACCACCAACTCCCGCGGCCAGCGGCTGCCCCAGAAG GGAGACGTGGAGATGCTGTGCGGCGGGCCGCCCTGCCAGGGCTTCAGCGGCATGAACCGCTTCAATTCGCGCACCTACTCCAAGTTCAAA AACTCTCTGGTGGTTTCCTTCCTCAGCTACTGCGACTACTACCGGCCCCGGTTCTTCCTCCTGGAGAATGTCAGGAACTTTGTCTCCTTC AAGCGCTCCATGGTCCTGAAGCTCACCCTCCGCTGCCTGGTCCGCATGGGCTATCAGTGCACCTTCGGCGTGCTGCAGGCCGGTCAGTAC GGCGTGGCCCAGACTAGGAGGCGGGCCATCATCCTGGCCGCGGCCCCTGGAGAGAAGCTCCCTCTGTTCCCGGAGCCACTGCACGTGTTT GCTCCCCGGGCCTGCCAGCTGAGCGTGGTGGTGGATGACAAGAAGTTTGTGAGCAACATAACCAGGTTGAGCTCGGGTCCTTTCCGGACC ATCACGGTGCGAGACACGATGTCCGACCTGCCGGAGGTGCGGAATGGAGCCTCGGCACTGGAGATCTCCTACAACGGGGAGCCTCAGTCC TGGTTCCAGAGGCAGCTCCGGGGCGCACAGTACCAGCCCATCCTCAGGGACCACATCTGTAAGGACATGAGTGCATTGGTGGCTGCCCGC ATGCGGCACATCCCCTTGGCCCCAGGGTCAGACTGGCGCGATCTGCCCAACATCGAGGTGCGGCTCTCAGACGGCACCATGGCCAGGAAG CTGCGGTATACCCACCATGACAGGAAGAACGGCCGCAGCAGCTCTGGGGCCCTCCGTGGGGTCTGCTCCTGCGTGGAAGCCGGCAAAGCC TGCGACCCCGCAGCCAGGCAGTTCAACACCCTCATCCCCTGGTGCCTGCCCCACACCGGGAACCGGCACAACCACTGGGCTGGCCTCTAT GGAAGGCTCGAGTGGGACGGCTTCTTCAGCACAACCGTCACCAACCCCGAGCCCATGGGCAAGCAGGGCCGCGTGCTCCACCCAGAGCAG CACCGTGTGGTGAGCGTGCGGGAGTGTGCCCGCTCCCAGGGCTTCCCTGACACCTACCGGCTCTTCGGCAACATCCTGGACAAGCACCGG CAGGTCCAGAACGTCTCCCAGTCCATGGAGGTCCTTGAGTTGCGGACGTATCGCGACCTCCAGTATGTACGCGGCATGGAGACCCTCATG CGGAGCCTGGATGCGCGGCTCCGGGCAGCTGATGGGTCCCTCTCGGCCAAGAGCTTCCAGGAGCTGAAGGACAGGATGACGGAACTGTTG CCCCTGAGCTCGGTCCTGGAGCAGTACAAGGCAGACACGCGGACCATTGTACGCTTGCGGGAGGAGGTGAGGAATCTCTCCGGCAGTCTG GCGGCCATTCAGGAGGAGATGGGTGCCTACGGGTATGAGGACCTGCAGCAACGGGTGATGGCCCTGGAGGCCCGGCTCCACGCCTGCGCC CAGAAGCTGGGCTGTGGGAAGCTGACCGGGGTCAGTAACCCCATCACCGTTCGGGCCATGGGGTCCCGCTTCGGCTCCTGGATGACTGAC ACGATGGCCCCCAGTGCGGATAGCCGGGTCTGGTACATGGATGGCTATTACAAAGGCCGCCGGGTCCTGGAGTTCCGTACCCTGGGAGAC TTCATCAAAGGCCAGAACTTTATCCAGCACCTGCTGCCCCAGCCGTGGGCGGGCACGGGCCACGTGGTGTACAACGGCTCCCTGTTCTAT AACAAGTACCAGAGCAACGTGGTGGTCAAATACCACTTCCGCTCGCGCTCTGTGCTGGTGCAGAGGAGCCTCCCGGGCGCCGGTTACAAC AACACCTTCCCCTACTCCTGGGGCGGCTTCTCCGACATGGACTTCATGGTGGACGAGAGCGGGCTCTGGGCTGTGTACACCACCAACCAG AACGCGGGCAACATCGTGGTCAGCCGGCTGGACCCGCACACCCTCGAGGTCATGCGGTCCTGGGACACCGGCTACCCCAAGCGCAGCGCT GGCGAGGCCTTCATGATCTGCGGTGTGCTCTACGTGACCAACTCCCACCTGGCTGGGGCCAAGGTCTACTTCGCCTATTTTACCAACACG TCCAGTTACGAGTACACGGACGTGCCCTTCCACAACCAGTATTCCCACATCTCGATGCTGGATTACAACCCCCGGGAGCGCGCCCTCTAT ACCTGGAACAACGGCCACCAGGTGCTCTACAATGTCACCCTGTTTCACGTCATCAGCACCTCTGGGGACCCCTGAGCCAATGCTGTGGCT CGGGCTGCTGCCTGGGGGGCCTCTGGGGGCTGGGGGCCCTTTTCATTCTGCCTGTGTCCCTCAAGGGTGATCTCTCTGTCTCTGTCACGC CCTTTCTCCCCGCCTTTTTGCTGGGCTTTTGTTCTCTGCCTATGTATTTCTGTCTATTTTTTCAATTTCCCCTCTTCTCCTTTATTGATC TCTGCTTTTAATACACCACTTCTTTCTTTCTGCCTTTTTATGGATGTCTTTTTCTTTTTATGGCTCTGGTTCTCCAGTTCTTTCCGTCTC TGCCTCTCTCTGTCTCTCTCTCTCTGTCCTTCCACCCCTCCCTCCTTGCTTCCCACCCATTCCTCATCCCTCACTCCCACCCCCACCCCC ACCCCCAGGAGTTGAGTGCATGGATCTGTTTCTTTTTTTATTTACACTTTTTCTTTCCGGTTTGCCGGAATAAACAGGACCTTTGACATT |
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FusionGenePPI for DNMT1_OLFM2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| DNMT1 | RGS6, DNMT3B, CBX5, SUV39H1, CBX1, PCNA, HDAC2, DMAP1, RB1, E2F1, HDAC1, TRIM27, DNMT3A, UHRF1, MBD2, MECP2, CXXC1, USP7, SETD7, SP1, SP3, EHMT2, EZH2, EED, BAZ2A, STAT3, SMARCA5, TP53, CHEK1, HELLS, WT1, SUZ12, TCF3, HSPA4, SNRPG, HSPA5, RAD9A, AKT1, KAT5, GSK3B, CSNK2B, RPS6KA6, DAXX, GADD45A, UHRF2, TRIM28, ZFP57, SIRT1, DNMT1, RUNX1T1, RUNX1, SIRT7, SH3KBP1, KDM1A, NR2C1, NR2C2, MTA1, MTA2, CHD4, RBBP4, MBD3, POLD3, HDAC3, CBX6, RELB, KIAA0101, NRIP1, CTBP1, YWHAQ, PARP1, BRCA1, CDKL4, DNAJC2, GCN1L1, ZFR, NTRK1, HIST3H3, HIST2H2AC, B9D2, HIST1H3E, CDK2, MYH14, BRAP, MKL1, CCNB1, SNAI1, CDC14B, LASP1, FOXA1, BRD1, PRKAA2, RBBP7 | OLFM2 | SRSF5, ST13, BLOC1S6, KRTAP10-3, OLFM1, ZFHX4, RNF40, TUBB1, DVL2, FEM1B, OLFM3, KDM5C, MSTO1, LRIF1, ZSWIM8, CBY1, EGFL7, DTNB, SDF2L1, DPYSL4, METTL3, PEX6, GALNS, BMP7, ZNF507, C15orf39, FUT11, NCOR1, CTDNEP1, BANP, VCPIP1, USP54, GPATCH8, N4BP2L2, DNAJB9, HAUS8 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1_120 | 1575 | 1617 | DMAP1 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1_120 | 1591 | 1633 | DMAP1 |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1_148 | 1575 | 1617 | DNMT3A |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1_148 | 1591 | 1633 | DNMT3A |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 149_217 | 1575 | 1617 | DNMT3B |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 149_217 | 1591 | 1633 | DNMT3B |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 163_174 | 1575 | 1617 | PCNA |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 163_174 | 1591 | 1633 | PCNA |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 308_606 | 1575 | 1617 | the PRC2/EED-EZH2 complex |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 308_606 | 1591 | 1633 | the PRC2/EED-EZH2 complex |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000340748 | - | 38 | 40 | 1121_1616 | 1575 | 1617 | the PRC2/EED-EZH2 complex |
| Hgene | DNMT1 | chr19:10246412 | chr19:9968537 | ENST00000359526 | - | 39 | 41 | 1121_1616 | 1591 | 1633 | the PRC2/EED-EZH2 complex |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DNMT1_OLFM2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | DNMT1 | P26358 | DB01035 | Procainamide | DNA (cytosine-5)-methyltransferase 1 | small molecule | approved |
| Hgene | DNMT1 | P26358 | DB00928 | Azacitidine | DNA (cytosine-5)-methyltransferase 1 | small molecule | approved|investigational |
| Hgene | DNMT1 | P26358 | DB01099 | Flucytosine | DNA (cytosine-5)-methyltransferase 1 | small molecule | approved|investigational |
| Hgene | DNMT1 | P26358 | DB01262 | Decitabine | DNA (cytosine-5)-methyltransferase 1 | small molecule | approved|investigational |
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RelatedDiseases for DNMT1_OLFM2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | DNMT1 | C0036341 | Schizophrenia | 4 | PSYGENET |
| Hgene | DNMT1 | C0005586 | Bipolar Disorder | 2 | PSYGENET |
| Hgene | DNMT1 | C0038356 | Stomach Neoplasms | 2 | CTD_human |
| Hgene | DNMT1 | C0001418 | Adenocarcinoma | 1 | CTD_human |
| Hgene | DNMT1 | C0003469 | Anxiety Disorders | 1 | CTD_human |
| Hgene | DNMT1 | C0004096 | Asthma | 1 | CTD_human |
| Hgene | DNMT1 | C0009375 | Colonic Neoplasms | 1 | CTD_human |
| Hgene | DNMT1 | C0025149 | Medulloblastoma | 1 | CTD_human |
| Hgene | DNMT1 | C0027889 | Hereditary Sensory and Autonomic Neuropathies | 1 | CTD_human |
| Hgene | DNMT1 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | DNMT1 | C0282612 | Prostatic Intraepithelial Neoplasias | 1 | CTD_human |
| Hgene | DNMT1 | C0497327 | Dementia | 1 | CTD_human;HPO |
| Hgene | DNMT1 | C0525045 | Mood Disorders | 1 | PSYGENET |
| Hgene | DNMT1 | C0993582 | Arthritis, Experimental | 1 | CTD_human |
| Hgene | DNMT1 | C1384666 | hearing impairment | 1 | CTD_human |
| Hgene | DNMT1 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| Hgene | DNMT1 | C3279885 | Hereditary Sensory and Autonomic Neuropathy Type Ie | 1 | ORPHANET;UNIPROT |
| Hgene | DNMT1 | C3807295 | CEREBELLAR ATAXIA, DEAFNESS, AND NARCOLEPSY, AUTOSOMAL DOMINANT | 1 | ORPHANET;UNIPROT |
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