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Fusion gene ID: 10186 |
FusionGeneSummary for DNAH1_PRKCD |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DNAH1_PRKCD | Fusion gene ID: 10186 | Hgene | Tgene | Gene symbol | DNAH1 | PRKCD | Gene ID | 25981 | 5580 |
| Gene name | dynein axonemal heavy chain 1 | protein kinase C delta | |
| Synonyms | CILD37|DNAHC1|HDHC7|HL-11|HL11|HSRF-1|SPGF18|XLHSRF-1 | ALPS3|CVID9|MAY1|PKCD|nPKC-delta | |
| Cytomap | 3p21.1 | 3p21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | dynein heavy chain 1, axonemalaxonemal beta dynein heavy chain 1ciliary dynein heavy chain 1dynein, axonemal, heavy polypeptide 1heat shock regulated protein 1testicular tissue protein Li 60 | protein kinase C delta typeprotein kinase C delta VIIItyrosine-protein kinase PRKCD | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9P2D7 | Q05655 | |
| Ensembl transtripts involved in fusion gene | ENST00000420323, ENST00000466628, | ENST00000394729, ENST00000330452, ENST00000477794, | |
| Fusion gene scores | * DoF score | 5 X 5 X 4=100 | 3 X 4 X 3=36 |
| # samples | 5 | 4 | |
| ** MAII score | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: DNAH1 [Title/Abstract] AND PRKCD [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DNAH1 | GO:0036159 | inner dynein arm assembly | 24360805 |
| Tgene | PRKCD | GO:0006468 | protein phosphorylation | 10713049|16611985 |
| Tgene | PRKCD | GO:0006915 | apoptotic process | 10770950 |
| Tgene | PRKCD | GO:0016572 | histone phosphorylation | 19059439 |
| Tgene | PRKCD | GO:0018105 | peptidyl-serine phosphorylation | 18285462 |
| Tgene | PRKCD | GO:0018107 | peptidyl-threonine phosphorylation | 10770950 |
| Tgene | PRKCD | GO:0032147 | activation of protein kinase activity | 10713049 |
| Tgene | PRKCD | GO:0042119 | neutrophil activation | 10770950 |
| Tgene | PRKCD | GO:0070301 | cellular response to hydrogen peroxide | 10713049 |
| Tgene | PRKCD | GO:0071447 | cellular response to hydroperoxide | 19059439 |
| Tgene | PRKCD | GO:1904385 | cellular response to angiotensin | 18285462 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-24-1603-01A | DNAH1 | chr3 | 52391751 | + | PRKCD | chr3 | 53221356 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000420323 | ENST00000394729 | DNAH1 | chr3 | 52391751 | + | PRKCD | chr3 | 53221356 | + |
| In-frame | ENST00000420323 | ENST00000330452 | DNAH1 | chr3 | 52391751 | + | PRKCD | chr3 | 53221356 | + |
| 5CDS-intron | ENST00000420323 | ENST00000477794 | DNAH1 | chr3 | 52391751 | + | PRKCD | chr3 | 53221356 | + |
| intron-3CDS | ENST00000466628 | ENST00000394729 | DNAH1 | chr3 | 52391751 | + | PRKCD | chr3 | 53221356 | + |
| intron-3CDS | ENST00000466628 | ENST00000330452 | DNAH1 | chr3 | 52391751 | + | PRKCD | chr3 | 53221356 | + |
| intron-intron | ENST00000466628 | ENST00000477794 | DNAH1 | chr3 | 52391751 | + | PRKCD | chr3 | 53221356 | + |
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FusionProtFeatures for DNAH1_PRKCD |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DNAH1 | PRKCD |
| Calcium-independent, phospholipid- and diacylglycerol(DAG)-dependent serine/threonine-protein kinase that playscontrasting roles in cell death and cell survival by functioningas a pro-apoptotic protein during DNA damage-induced apoptosis,but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well assurvival of several cancers, is required for oxygen radicalproduction by NADPH oxidase and acts as positive or negativeregulator in platelet functional responses. Negatively regulates Bcell proliferation and also has an important function in self-antigen induced B cell tolerance induction. Upon DNA damage,activates the promoter of the death-promoting transcription factorBCLAF1/Btf to trigger BCLAF1-mediated p53/TP53 gene transcriptionand apoptosis. In response to oxidative stress, interact with andactivate CHUK/IKKA in the nucleus, causing the phosphorylation ofp53/TP53. In the case of ER stress or DNA damage-inducedapoptosis, can form a complex with the tyrosine-protein kinaseABL1 which trigger apoptosis independently of p53/TP53. In cytosolcan trigger apoptosis by activating MAPK11 or MAPK14, inhibitingAKT1 and decreasing the level of X-linked inhibitor of apoptosisprotein (XIAP), whereas in nucleus induces apoptosis via theactivation of MAPK8 or MAPK9. Upon ionizing radiation treatment,is required for the activation of the apoptosis regulators BAX andBAK, which trigger the mitochondrial cell death pathway. Canphosphorylate MCL1 and target it for degradation which issufficient to trigger for BAX activation and apoptosis. Isrequired for the control of cell cycle progression both at G1/Sand G2/M phases. Mediates phorbol 12-myristate 13-acetate (PMA)-induced inhibition of cell cycle progression at G1/S phase by up-regulating the CDK inhibitor CDKN1A/p21 and inhibiting the cyclinCCNA2 promoter activity. In response to UV irradiation canphosphorylate CDK1, which is important for the G2/M DNA damagecheckpoint activation. Can protect glioma cells from the apoptosisinduced by TNFSF10/TRAIL, probably by inducing increasedphosphorylation and subsequent activation of AKT1. Is highlyexpressed in a number of cancer cells and promotes cell survivaland resistance against chemotherapeutic drugs by inducing cyclinD1 (CCND1) and hyperphosphorylation of RB1, and via several pro-survival pathways, including NF-kappa-B, AKT1 and MAPK1/3(ERK1/2). Can also act as tumor suppressor upon mitogenicstimulation with PMA or TPA. In N-formyl-methionyl-leucyl-phenylalanine (fMLP)-treated cells, is required for NCF1 (p47-phox) phosphorylation and activation of NADPH oxidase activity,and regulates TNF-elicited superoxide anion production inneutrophils, by direct phosphorylation and activation of NCF1 orindirectly through MAPK1/3 (ERK1/2) signaling pathways. May alsoplay a role in the regulation of NADPH oxidase activity ineosinophil after stimulation with IL5, leukotriene B4 or PMA. Incollagen-induced platelet aggregation, acts a negative regulatorof filopodia formation and actin polymerization by interactingwith and negatively regulating VASP phosphorylation. Downstream ofPAR1, PAR4 and CD36/GP4 receptors, regulates differentiallyplatelet dense granule secretion; acts as a positive regulator inPAR-mediated granule secretion, whereas it negatively regulatesCD36/GP4-mediated granule release. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin. The catalytic subunit phosphorylates 14-3-3 proteins(YWHAB, YWHAZ and YWHAH) in a sphingosine-dependent fashion (Bysimilarity). Phosphorylates ELAVL1 in response to angiotensin-2treatment (PubMed:18285462). {ECO:0000250,ECO:0000269|PubMed:11748588, ECO:0000269|PubMed:11877440,ECO:0000269|PubMed:15774464, ECO:0000269|PubMed:16940418,ECO:0000269|PubMed:18285462, ECO:0000269|PubMed:19587372,ECO:0000269|PubMed:19801500}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 1216_1239 | 1326 | 4266 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 968_998 | 1326 | 4266 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >PRKCD | chr3:52391751 | chr3:53221356 | ENST00000330452 | + | 13 | 19 | 604_675 | 450 | 677 | Domain | Note=AGC-kinase C-terminal |
| Tgene | >PRKCD | chr3:52391751 | chr3:53221356 | ENST00000394729 | + | 12 | 18 | 604_675 | 450 | 677 | Domain | Note=AGC-kinase C-terminal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 2836_2917 | 1326 | 4266 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 3062_3123 | 1326 | 4266 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 3185_3211 | 1326 | 4266 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 3433_3500 | 1326 | 4266 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 4095_4115 | 1326 | 4266 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 2167_2172 | 1326 | 4266 | Compositional bias | Note=Poly-Glu |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 1581_1588 | 1326 | 4266 | Motif | Note=GPAGTGKT motif |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 1631_1637 | 1326 | 4266 | Motif | Note=CFDEFNR motif |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 1862_1869 | 1326 | 4266 | Nucleotide binding | ATP |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 2227_2234 | 1326 | 4266 | Nucleotide binding | ATP |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 2586_2593 | 1326 | 4266 | Nucleotide binding | ATP |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 1543_1764 | 1326 | 4266 | Region | AAA 1 |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 1824_2057 | 1326 | 4266 | Region | AAA 2 |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 1_1542 | 1326 | 4266 | Region | Stem |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 2189_2449 | 1326 | 4266 | Region | AAA 3 |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 2547_2799 | 1326 | 4266 | Region | AAA 4 |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 2814_3112 | 1326 | 4266 | Region | Stalk |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 3262_3492 | 1326 | 4266 | Region | AAA 5 |
| Hgene | >DNAH1 | chr3:52391751 | chr3:53221356 | ENST00000420323 | + | 23 | 78 | 3705_3924 | 1326 | 4266 | Region | AAA 6 |
| Tgene | PRKCD | chr3:52391751 | chr3:53221356 | ENST00000330452 | + | 13 | 19 | 1_90 | 450 | 677 | Domain | Note=C2 |
| Tgene | PRKCD | chr3:52391751 | chr3:53221356 | ENST00000330452 | + | 13 | 19 | 349_603 | 450 | 677 | Domain | Protein kinase |
| Tgene | PRKCD | chr3:52391751 | chr3:53221356 | ENST00000394729 | + | 12 | 18 | 1_90 | 450 | 677 | Domain | Note=C2 |
| Tgene | PRKCD | chr3:52391751 | chr3:53221356 | ENST00000394729 | + | 12 | 18 | 349_603 | 450 | 677 | Domain | Protein kinase |
| Tgene | PRKCD | chr3:52391751 | chr3:53221356 | ENST00000330452 | + | 13 | 19 | 355_363 | 450 | 677 | Nucleotide binding | ATP |
| Tgene | PRKCD | chr3:52391751 | chr3:53221356 | ENST00000394729 | + | 12 | 18 | 355_363 | 450 | 677 | Nucleotide binding | ATP |
| Tgene | PRKCD | chr3:52391751 | chr3:53221356 | ENST00000330452 | + | 13 | 19 | 158_208 | 450 | 677 | Zinc finger | Phorbol-ester/DAG-type 1 |
| Tgene | PRKCD | chr3:52391751 | chr3:53221356 | ENST00000330452 | + | 13 | 19 | 230_280 | 450 | 677 | Zinc finger | Phorbol-ester/DAG-type 2 |
| Tgene | PRKCD | chr3:52391751 | chr3:53221356 | ENST00000394729 | + | 12 | 18 | 158_208 | 450 | 677 | Zinc finger | Phorbol-ester/DAG-type 1 |
| Tgene | PRKCD | chr3:52391751 | chr3:53221356 | ENST00000394729 | + | 12 | 18 | 230_280 | 450 | 677 | Zinc finger | Phorbol-ester/DAG-type 2 |
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FusionGeneSequence for DNAH1_PRKCD |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_DNAH1_ENST00000420323_chr3_52391751_+_PRKCD_ENST00000394729_chr3_53221356_+_1553aa MEQPNSKGTSLGRTPQGPECSSAPAVQVGTHRGLETNPGKILPGSDTGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYP LMKQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQCIGSTTRLLAQTDFPLQAYEPKMQVPFQ VLPGQHPRKIEIERRKQQYLSLDIEQLLFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKVFDNEDFDCRTPREWINMGLEPGS LDRKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRPILNAGVTTEGRPPLQVCQYWVPRIQ LLFCAEDPCMFAQRVVQANALRKNTEALLLYNLTVDCMPSDGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDTERSMN KINFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAECNKVTAMSLFHSSLSKYSHLE EFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTC CSVLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHTSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLESVG LHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINT DNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKITEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLY NLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQ QLAMLYNNRERIFSLPITNTDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEV ALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWS TILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQL PVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSETLETKRSAFPRFTAAEIMCGLQFLHSKGIIYRDL KLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDTIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDT PHTPRWITKESKDILEKLFEREPTKRLGVTGNIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDS >In-frame_DNAH1_ENST00000420323_chr3_52391751_+_PRKCD_ENST00000330452_chr3_53221356_+_1553aa MEQPNSKGTSLGRTPQGPECSSAPAVQVGTHRGLETNPGKILPGSDTGLGNPPALDPKLPHLPLPPAPPTLSDLGQPRKSPLTGTDKKYP LMKQRGFYSDILSPGTLDQLGEVCRGPRMSQNLLRQADLDKFTPRVGSFEVPEDFQERMEQQCIGSTTRLLAQTDFPLQAYEPKMQVPFQ VLPGQHPRKIEIERRKQQYLSLDIEQLLFSQGIDSNKLMPRHLDHQHPQTIEQGHDPIFPIYLPLKVFDNEDFDCRTPREWINMGLEPGS LDRKPVPGKALLPTDDFLGHEDPKSQKLKYKWCEVGVLDYDEEKKLYLVHKTDEKGLVRDEMGRPILNAGVTTEGRPPLQVCQYWVPRIQ LLFCAEDPCMFAQRVVQANALRKNTEALLLYNLTVDCMPSDGQHVISEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVSLDTERSMN KINFDHVVSSKPETFSYVTLPKKEEEQVPERGLVSVPKYHFWEQKEDFTFVSLLTRPEVITALSKVRAECNKVTAMSLFHSSLSKYSHLE EFEQIQSQTFSQVQMFLKDSWISSLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELVKYMLQDTLRFLVQDSLASFSQFISDTC CSVLNCTDDMVWGDDLINSPYRPRKNPLFIMDLVLDSSGVHTSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLESVG LHEPLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVVLTHLREKEILDSSLPSSIIIGPFYINT DNVKQSLSKKRKALATSVLDILAKNLHKEVDSICEEFRSISRKITEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLY NLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQ QLAMLYNNRERIFSLPITNTDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTMHKCVKQFKDMPACQEV ALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWS TILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQL PVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSETLETKRSAFPRFTAAEIMCGLQFLHSKGIIYRDL KLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDTIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDT PHTPRWITKESKDILEKLFEREPTKRLGVTGNIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_DNAH1_ENST00000420323_chr3_52391751_+_PRKCD_ENST00000394729_chr3_53221356_+_4659nt ATGGAGCAGCCTAACAGTAAAGGCTATAGCCTGGGAAGGACCCCTCAGGGCCCAGAGTGCAGCAGTGCTCCTGCAGTCCAAGTGGGGACC CACAGGGGCCTAGAGTATAACCCGGGGAAGATTCTTCCAGGATCAGACTATGGGTTGGGAAATCCTCCAGCCCTTGACCCCAAGCTCCCA CATTTACCCCTGCCCCCGGCCCCACCCACACTCTCAGACTTGGGGCAGCCACGGAAGTCACCCCTGACAGGCACTGATAAGAAGTACCCG CTGATGAAGCAGCGTGGGTTCTACTCCGACATCCTCAGCCCTGGAACCTTAGATCAACTTGGGGAGGTATGTCGTGGCCCCCGAATGAGC CAGAACCTCCTGCGGCAGGCTGACCTTGACAAGTTCACCCCAAGAGTCGGAAGCTTTGAGGTTCCTGAAGACTTCCAGGAGCGCATGGAG CAGCAGTGCATCGGGTCCACCACCCGGCTGCTCGCCCAGACTGACTTCCCACTGCAGGCCTACGAGCCCAAGATGCAGGTGCCTTTCCAG GTGCTGCCAGGCCAGCATCCTCGCAAGATTGAGATCGAGAGGAGGAAACAGCAGTACCTGAGCCTGGACATTGAGCAGTTGCTGTTCAGC CAGGGCATCGACTCCAACAAGCTCATGCCCAGGCACCTGGACCACCAGCACCCCCAAACCATCGAACAGGGCCATGACCCAATCTTCCCC ATCTACCTCCCACTGAAGGTATTTGACAATGAGGACTTTGACTGCCGGACTCCCAGAGAGTGGATCAACATGGGCTTGGAGCCAGGGTCT CTGGACAGGAAACCTGTCCCGGGAAAAGCCCTCTTGCCCACTGATGACTTCCTGGGGCATGAGGACCCCAAGAGTCAGAAGCTGAAGTAC AAATGGTGCGAGGTCGGCGTCCTGGACTACGACGAGGAGAAGAAGCTATACCTGGTACACAAGACAGACGAGAAAGGCCTGGTGCGAGAT GAGATGGGGAGGCCCATCCTGAATGCAGGGGTCACCACTGAAGGAAGGCCACCCCTTCAGGTCTGTCAGTACTGGGTGCCACGGATCCAG CTTCTCTTCTGCGCTGAGGACCCTTGCATGTTCGCACAACGTGTGGTCCAGGCCAACGCCCTGCGCAAGAACACGGAAGCACTGCTGCTC TACAACTTGTATGTGGACTGCATGCCCTCTGACGGCCAGCATGTCATCAGTGAACAGAGCCTGAGCAAGATCAAGCAGTGGGCCCTGAGC ACGCCTCGGATGCGCAAAGGCCCCTCGGTTCTAGAGCACCTCAGCAGTCTTGCCAGAGAAGTGAGCCTGGACTATGAGCGCAGCATGAAC AAGATCAACTTTGACCACGTTGTCTCTTCCAAGCCCGAGACCTTCTCCTACGTCACCCTCCCCAAGAAGGAGGAGGAGCAGGTGCCTGAG CGAGGGCTGGTGAGTGTCCCCAAGTACCACTTCTGGGAGCAGAAGGAGGACTTCACTTTCGTGTCCCTGCTCACACGGCCAGAGGTCATC ACGGCCCTCAGCAAGGTGAGGGCCGAGTGCAACAAGGTGACCGCCATGTCCCTGTTCCACTCGAGCCTCTCCAAGTACAGCCACCTGGAG GAATTTGAGCAGATCCAGTCACAGACCTTCTCCCAGGTGCAGATGTTCCTCAAGGACAGCTGGATCAGCTCGCTAAAGGTGGCCATGCGC AGCAGCCTGCGCGACATGAGCAAGGGCTGGTACAACCTCTACGAGACCAACTGGGAGGTGTACCTCATGTCCAAGCTGCGCAAGCTGATG GAGCTGGTGAAGTACATGCTGCAGGACACACTGCGCTTCCTGGTGCAGGACTCACTTGCCAGCTTCTCACAGTTCATCAGCGACACCTGT TGCAGCGTGCTCAACTGCACCGATGACATGGTCTGGGGTGACGACTTAATTAACAGCCCCTACAGGCCCCGGAAGAATCCCCTGTTCATC ATGGACCTGGTGCTGGACAGCTCTGGGGTGCACTATAGCACCCCACTGGAGCAGTTTGAGGCATCTCTGCTGAACCTCTTCGACAAGGGC ATCCTGGCCACCCATGCCGTGCCCCAGCTGGAGAAGCTGGTGATGGAGGACATCTTCATCAGCGGTGACCCCCTGCTGGAGTCCGTGGGC CTTCATGAGCCACTGGTGGAAGAGCTACGGGCCACCATTGCCAGTGCCGTGTCCAAGGCCATGATCCCACTGCAGGCCTACGCCAAGGAG TACCGAAAGTACCTGGAGCTGAACAACAATGACATTGCCTCCTTTCTCAAAACCTACCAGACGCAGGGCCTGTTGGCCCAGGAGGTGCGG GAGGTAGTGCTCACCCACCTGCGGGAGAAGGAGATCCTGGACAGCTCGCTGCCCAGCAGCATCATCATTGGGCCTTTCTACATCAACACC GACAATGTCAAGCAGAGCCTGTCCAAGAAACGCAAGGCCCTGGCCACTTCCGTGCTGGACATCCTTGCCAAGAACCTGCATAAGGAGGTG GATAGCATCTGCGAGGAGTTCCGCAGCATCAGCCGCAAGATCTATGAGAAGCCCAACAGCATTGAGGAGCTGGCTGAGCTGCGAGAGTGG ATGAAGGGCATCCCGGAGAGGCTGGTGGGCCTGGAGGAGCGGATTGTGAAGGTCATGGATGACTACCAGGTCATGGATGAATTCCTCTAC AACCTCAGCTCAGATGACTTCAATGACAAATGGATTGCCAGCAACTGGCCTTCTAAGATCCTTGGGCAGATAGAGCTGGTGCAGCAGCAG CATGTGGAGGATGAGGAGAAGTTCCGCAAAATCCAGATCATGGATCAGAACAACTTCCAAGAGAAGCTGGAAGGGCTGCAGCTGGTAGTA GCTGGCTTCTCCATCCATGTGGAGATTTCACGTGCACACGAGATCGCCAACGAGGTGCGGCGTGTCAAGAAGCAGCTGAAGGACTGCCAG CAGCTGGCCATGCTCTACAACAACCGCGAGCGCATCTTCAGCTTGCCCATCACCAATTATGACAAGCTCTCCAGGATGGTGAAGGAGTTC CAACCCTACCTGGACCTTTGGACCACAGCGTCTGACTGGCTGCGCTGGTCGGAGAGCTGGATGAATGACCCCCTCTCTGCCATCGATGCT GAGCAGCTGGAGAAGAACGTGGTTGAAGCCTTCAAGACCATGCACAAGTGCGTGAAGCAGTTTAAGGACATGCCAGCCTGCCAGGAAGTG GCCTTGGACATCCGGGCCCGCATCGAGGAGTTCAAACCATACATCCCACTGATCCAGGGGCTGCGCAACCCTGGCATGCGGATCCGGCAC TGGGAGACACTGTCCAACCAGATCAACATCAATGTCAGGCCCAAGGCCAACCTGACCTTTGCTCGCTGCCTGGAGATGAACCTGCAGGAC CATATCGAGAGCATCAGCAAGGTGGCTGAGGTGGCTGGCAAGGAGTACGCCATCGAGCAGGCACTGGACAAGATGGAGAAGGAGTGGTCG ACCATCCTGTTCAATGTACTGCCCTACAAGGCGACAGACACCTACATCCTGAAGAGCCCGGACGAGGCCTCACAGCTGCTGGACGACCAC ATCGTCATGACCCAGAATATGTCATTTTCACCCTACAAGAAGCCCTTTGAGCAGCGCATCAACTCCTGGGAGAACAAACTGAAGCTGACC CAGGAGGTTCTGGAGGAGTGGCTGAACTGTCAGCGGTCCTGGCTCTACCTGGAGCCCATCTTTAGCTCTGAGGACATCAACCAGCAGCTG CCTGTGGAGAGCAAGCGCTACCAGACCATGGAGCGGATCTGGAAGAAGATCATGAAGAATGCCTACGAGAACCGGGAGGTGATCAATGTG TGTTCCGACCTGAGAATGCTGGACAGCCTGCGGGACTGCAACAAGATTCTGGACCTGGTGCAGAAGGGCCTCAGCGAGTATCTGGAGACC AAGAGGAGCGCCTTCCCCAGGTTTTATGCCGCTGAGATAATGTGTGGACTGCAGTTTCTACACAGCAAGGGCATCATTTACAGGGACCTC AAACTGGACAATGTGCTGCTGGACCGGGATGGCCACATCAAGATTGCCGACTTTGGGATGTGCAAAGAGAACATATTCGGGGAGAGCCGG GCCAGCACCTTCTGCGGCACCCCTGACTATATCGCCCCTGAGATCCTACAGGGCCTGAAGTACACATTCTCTGTGGACTGGTGGTCTTTC GGGGTCCTTCTGTACGAGATGCTCATTGGCCAGTCCCCCTTCCATGGTGATGATGAGGATGAACTCTTCGAGTCCATCCGTGTGGACACG CCACATTATCCCCGCTGGATCACCAAGGAGTCCAAGGACATCCTGGAGAAGCTCTTTGAAAGGGAACCAACCAAGAGGCTGGGAGTGACC GGAAACATCAAAATCCACCCCTTCTTCAAGACCATAAACTGGACTCTGCTGGAAAAGCGGAGGTTGGAGCCACCTTTCAGGCCCAAAGTG AAGTCACCCAGAGACTACAGTAACTTTGACCAGGAGTTCCTGAACGAGAAGGCGCGCCTCTCCTACAGCGACAAGAACCTCATCGACTCC >In-frame_DNAH1_ENST00000420323_chr3_52391751_+_PRKCD_ENST00000330452_chr3_53221356_+_4659nt ATGGAGCAGCCTAACAGTAAAGGCTATAGCCTGGGAAGGACCCCTCAGGGCCCAGAGTGCAGCAGTGCTCCTGCAGTCCAAGTGGGGACC CACAGGGGCCTAGAGTATAACCCGGGGAAGATTCTTCCAGGATCAGACTATGGGTTGGGAAATCCTCCAGCCCTTGACCCCAAGCTCCCA CATTTACCCCTGCCCCCGGCCCCACCCACACTCTCAGACTTGGGGCAGCCACGGAAGTCACCCCTGACAGGCACTGATAAGAAGTACCCG CTGATGAAGCAGCGTGGGTTCTACTCCGACATCCTCAGCCCTGGAACCTTAGATCAACTTGGGGAGGTATGTCGTGGCCCCCGAATGAGC CAGAACCTCCTGCGGCAGGCTGACCTTGACAAGTTCACCCCAAGAGTCGGAAGCTTTGAGGTTCCTGAAGACTTCCAGGAGCGCATGGAG CAGCAGTGCATCGGGTCCACCACCCGGCTGCTCGCCCAGACTGACTTCCCACTGCAGGCCTACGAGCCCAAGATGCAGGTGCCTTTCCAG GTGCTGCCAGGCCAGCATCCTCGCAAGATTGAGATCGAGAGGAGGAAACAGCAGTACCTGAGCCTGGACATTGAGCAGTTGCTGTTCAGC CAGGGCATCGACTCCAACAAGCTCATGCCCAGGCACCTGGACCACCAGCACCCCCAAACCATCGAACAGGGCCATGACCCAATCTTCCCC ATCTACCTCCCACTGAAGGTATTTGACAATGAGGACTTTGACTGCCGGACTCCCAGAGAGTGGATCAACATGGGCTTGGAGCCAGGGTCT CTGGACAGGAAACCTGTCCCGGGAAAAGCCCTCTTGCCCACTGATGACTTCCTGGGGCATGAGGACCCCAAGAGTCAGAAGCTGAAGTAC AAATGGTGCGAGGTCGGCGTCCTGGACTACGACGAGGAGAAGAAGCTATACCTGGTACACAAGACAGACGAGAAAGGCCTGGTGCGAGAT GAGATGGGGAGGCCCATCCTGAATGCAGGGGTCACCACTGAAGGAAGGCCACCCCTTCAGGTCTGTCAGTACTGGGTGCCACGGATCCAG CTTCTCTTCTGCGCTGAGGACCCTTGCATGTTCGCACAACGTGTGGTCCAGGCCAACGCCCTGCGCAAGAACACGGAAGCACTGCTGCTC TACAACTTGTATGTGGACTGCATGCCCTCTGACGGCCAGCATGTCATCAGTGAACAGAGCCTGAGCAAGATCAAGCAGTGGGCCCTGAGC ACGCCTCGGATGCGCAAAGGCCCCTCGGTTCTAGAGCACCTCAGCAGTCTTGCCAGAGAAGTGAGCCTGGACTATGAGCGCAGCATGAAC AAGATCAACTTTGACCACGTTGTCTCTTCCAAGCCCGAGACCTTCTCCTACGTCACCCTCCCCAAGAAGGAGGAGGAGCAGGTGCCTGAG CGAGGGCTGGTGAGTGTCCCCAAGTACCACTTCTGGGAGCAGAAGGAGGACTTCACTTTCGTGTCCCTGCTCACACGGCCAGAGGTCATC ACGGCCCTCAGCAAGGTGAGGGCCGAGTGCAACAAGGTGACCGCCATGTCCCTGTTCCACTCGAGCCTCTCCAAGTACAGCCACCTGGAG GAATTTGAGCAGATCCAGTCACAGACCTTCTCCCAGGTGCAGATGTTCCTCAAGGACAGCTGGATCAGCTCGCTAAAGGTGGCCATGCGC AGCAGCCTGCGCGACATGAGCAAGGGCTGGTACAACCTCTACGAGACCAACTGGGAGGTGTACCTCATGTCCAAGCTGCGCAAGCTGATG GAGCTGGTGAAGTACATGCTGCAGGACACACTGCGCTTCCTGGTGCAGGACTCACTTGCCAGCTTCTCACAGTTCATCAGCGACACCTGT TGCAGCGTGCTCAACTGCACCGATGACATGGTCTGGGGTGACGACTTAATTAACAGCCCCTACAGGCCCCGGAAGAATCCCCTGTTCATC ATGGACCTGGTGCTGGACAGCTCTGGGGTGCACTATAGCACCCCACTGGAGCAGTTTGAGGCATCTCTGCTGAACCTCTTCGACAAGGGC ATCCTGGCCACCCATGCCGTGCCCCAGCTGGAGAAGCTGGTGATGGAGGACATCTTCATCAGCGGTGACCCCCTGCTGGAGTCCGTGGGC CTTCATGAGCCACTGGTGGAAGAGCTACGGGCCACCATTGCCAGTGCCGTGTCCAAGGCCATGATCCCACTGCAGGCCTACGCCAAGGAG TACCGAAAGTACCTGGAGCTGAACAACAATGACATTGCCTCCTTTCTCAAAACCTACCAGACGCAGGGCCTGTTGGCCCAGGAGGTGCGG GAGGTAGTGCTCACCCACCTGCGGGAGAAGGAGATCCTGGACAGCTCGCTGCCCAGCAGCATCATCATTGGGCCTTTCTACATCAACACC GACAATGTCAAGCAGAGCCTGTCCAAGAAACGCAAGGCCCTGGCCACTTCCGTGCTGGACATCCTTGCCAAGAACCTGCATAAGGAGGTG GATAGCATCTGCGAGGAGTTCCGCAGCATCAGCCGCAAGATCTATGAGAAGCCCAACAGCATTGAGGAGCTGGCTGAGCTGCGAGAGTGG ATGAAGGGCATCCCGGAGAGGCTGGTGGGCCTGGAGGAGCGGATTGTGAAGGTCATGGATGACTACCAGGTCATGGATGAATTCCTCTAC AACCTCAGCTCAGATGACTTCAATGACAAATGGATTGCCAGCAACTGGCCTTCTAAGATCCTTGGGCAGATAGAGCTGGTGCAGCAGCAG CATGTGGAGGATGAGGAGAAGTTCCGCAAAATCCAGATCATGGATCAGAACAACTTCCAAGAGAAGCTGGAAGGGCTGCAGCTGGTAGTA GCTGGCTTCTCCATCCATGTGGAGATTTCACGTGCACACGAGATCGCCAACGAGGTGCGGCGTGTCAAGAAGCAGCTGAAGGACTGCCAG CAGCTGGCCATGCTCTACAACAACCGCGAGCGCATCTTCAGCTTGCCCATCACCAATTATGACAAGCTCTCCAGGATGGTGAAGGAGTTC CAACCCTACCTGGACCTTTGGACCACAGCGTCTGACTGGCTGCGCTGGTCGGAGAGCTGGATGAATGACCCCCTCTCTGCCATCGATGCT GAGCAGCTGGAGAAGAACGTGGTTGAAGCCTTCAAGACCATGCACAAGTGCGTGAAGCAGTTTAAGGACATGCCAGCCTGCCAGGAAGTG GCCTTGGACATCCGGGCCCGCATCGAGGAGTTCAAACCATACATCCCACTGATCCAGGGGCTGCGCAACCCTGGCATGCGGATCCGGCAC TGGGAGACACTGTCCAACCAGATCAACATCAATGTCAGGCCCAAGGCCAACCTGACCTTTGCTCGCTGCCTGGAGATGAACCTGCAGGAC CATATCGAGAGCATCAGCAAGGTGGCTGAGGTGGCTGGCAAGGAGTACGCCATCGAGCAGGCACTGGACAAGATGGAGAAGGAGTGGTCG ACCATCCTGTTCAATGTACTGCCCTACAAGGCGACAGACACCTACATCCTGAAGAGCCCGGACGAGGCCTCACAGCTGCTGGACGACCAC ATCGTCATGACCCAGAATATGTCATTTTCACCCTACAAGAAGCCCTTTGAGCAGCGCATCAACTCCTGGGAGAACAAACTGAAGCTGACC CAGGAGGTTCTGGAGGAGTGGCTGAACTGTCAGCGGTCCTGGCTCTACCTGGAGCCCATCTTTAGCTCTGAGGACATCAACCAGCAGCTG CCTGTGGAGAGCAAGCGCTACCAGACCATGGAGCGGATCTGGAAGAAGATCATGAAGAATGCCTACGAGAACCGGGAGGTGATCAATGTG TGTTCCGACCTGAGAATGCTGGACAGCCTGCGGGACTGCAACAAGATTCTGGACCTGGTGCAGAAGGGCCTCAGCGAGTATCTGGAGACC AAGAGGAGCGCCTTCCCCAGGTTTTATGCCGCTGAGATAATGTGTGGACTGCAGTTTCTACACAGCAAGGGCATCATTTACAGGGACCTC AAACTGGACAATGTGCTGCTGGACCGGGATGGCCACATCAAGATTGCCGACTTTGGGATGTGCAAAGAGAACATATTCGGGGAGAGCCGG GCCAGCACCTTCTGCGGCACCCCTGACTATATCGCCCCTGAGATCCTACAGGGCCTGAAGTACACATTCTCTGTGGACTGGTGGTCTTTC GGGGTCCTTCTGTACGAGATGCTCATTGGCCAGTCCCCCTTCCATGGTGATGATGAGGATGAACTCTTCGAGTCCATCCGTGTGGACACG CCACATTATCCCCGCTGGATCACCAAGGAGTCCAAGGACATCCTGGAGAAGCTCTTTGAAAGGGAACCAACCAAGAGGCTGGGAGTGACC GGAAACATCAAAATCCACCCCTTCTTCAAGACCATAAACTGGACTCTGCTGGAAAAGCGGAGGTTGGAGCCACCTTTCAGGCCCAAAGTG AAGTCACCCAGAGACTACAGTAACTTTGACCAGGAGTTCCTGAACGAGAAGGCGCGCCTCTCCTACAGCGACAAGAACCTCATCGACTCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_DNAH1_ENST00000420323_chr3_52391751_+_PRKCD_ENST00000394729_chr3_53221356_+_5371nt GGGGGGTACCCAACCTATACGCAGACCCATTGAGCAGCCAGACTGCCCTAAACAGGGCTATGGAGTCCTTGTCCCTTCTAAGAGCTGTGG ACACCTTGCCTCCAGTTCCCCTCACAGTCCTTTCTTCCTTCTGCAGTGATCACTGAGTACCTGTGTGAATGCCAACAAGAAAAATAAAAC CACAGTTTGGATTCAGGAAAGGTTGCACCACCATCAGGTCTTGAAGGGAGCTTCGGCTGGGGCATCTCCCTGAGAAGCAGCATGGAGCAG CCTAACAGTAAAGGCTATAGCCTGGGAAGGACCCCTCAGGGCCCAGAGTGCAGCAGTGCTCCTGCAGTCCAAGTGGGGACCCACAGGGGC CTAGAGTATAACCCGGGGAAGATTCTTCCAGGATCAGACTATGGGTTGGGAAATCCTCCAGCCCTTGACCCCAAGCTCCCACATTTACCC CTGCCCCCGGCCCCACCCACACTCTCAGACTTGGGGCAGCCACGGAAGTCACCCCTGACAGGCACTGATAAGAAGTACCCGCTGATGAAG CAGCGTGGGTTCTACTCCGACATCCTCAGCCCTGGAACCTTAGATCAACTTGGGGAGGTATGTCGTGGCCCCCGAATGAGCCAGAACCTC CTGCGGCAGGCTGACCTTGACAAGTTCACCCCAAGAGTCGGAAGCTTTGAGGTTCCTGAAGACTTCCAGGAGCGCATGGAGCAGCAGTGC ATCGGGTCCACCACCCGGCTGCTCGCCCAGACTGACTTCCCACTGCAGGCCTACGAGCCCAAGATGCAGGTGCCTTTCCAGGTGCTGCCA GGCCAGCATCCTCGCAAGATTGAGATCGAGAGGAGGAAACAGCAGTACCTGAGCCTGGACATTGAGCAGTTGCTGTTCAGCCAGGGCATC GACTCCAACAAGCTCATGCCCAGGCACCTGGACCACCAGCACCCCCAAACCATCGAACAGGGCCATGACCCAATCTTCCCCATCTACCTC CCACTGAAGGTATTTGACAATGAGGACTTTGACTGCCGGACTCCCAGAGAGTGGATCAACATGGGCTTGGAGCCAGGGTCTCTGGACAGG AAACCTGTCCCGGGAAAAGCCCTCTTGCCCACTGATGACTTCCTGGGGCATGAGGACCCCAAGAGTCAGAAGCTGAAGTACAAATGGTGC GAGGTCGGCGTCCTGGACTACGACGAGGAGAAGAAGCTATACCTGGTACACAAGACAGACGAGAAAGGCCTGGTGCGAGATGAGATGGGG AGGCCCATCCTGAATGCAGGGGTCACCACTGAAGGAAGGCCACCCCTTCAGGTCTGTCAGTACTGGGTGCCACGGATCCAGCTTCTCTTC TGCGCTGAGGACCCTTGCATGTTCGCACAACGTGTGGTCCAGGCCAACGCCCTGCGCAAGAACACGGAAGCACTGCTGCTCTACAACTTG TATGTGGACTGCATGCCCTCTGACGGCCAGCATGTCATCAGTGAACAGAGCCTGAGCAAGATCAAGCAGTGGGCCCTGAGCACGCCTCGG ATGCGCAAAGGCCCCTCGGTTCTAGAGCACCTCAGCAGTCTTGCCAGAGAAGTGAGCCTGGACTATGAGCGCAGCATGAACAAGATCAAC TTTGACCACGTTGTCTCTTCCAAGCCCGAGACCTTCTCCTACGTCACCCTCCCCAAGAAGGAGGAGGAGCAGGTGCCTGAGCGAGGGCTG GTGAGTGTCCCCAAGTACCACTTCTGGGAGCAGAAGGAGGACTTCACTTTCGTGTCCCTGCTCACACGGCCAGAGGTCATCACGGCCCTC AGCAAGGTGAGGGCCGAGTGCAACAAGGTGACCGCCATGTCCCTGTTCCACTCGAGCCTCTCCAAGTACAGCCACCTGGAGGAATTTGAG CAGATCCAGTCACAGACCTTCTCCCAGGTGCAGATGTTCCTCAAGGACAGCTGGATCAGCTCGCTAAAGGTGGCCATGCGCAGCAGCCTG CGCGACATGAGCAAGGGCTGGTACAACCTCTACGAGACCAACTGGGAGGTGTACCTCATGTCCAAGCTGCGCAAGCTGATGGAGCTGGTG AAGTACATGCTGCAGGACACACTGCGCTTCCTGGTGCAGGACTCACTTGCCAGCTTCTCACAGTTCATCAGCGACACCTGTTGCAGCGTG CTCAACTGCACCGATGACATGGTCTGGGGTGACGACTTAATTAACAGCCCCTACAGGCCCCGGAAGAATCCCCTGTTCATCATGGACCTG GTGCTGGACAGCTCTGGGGTGCACTATAGCACCCCACTGGAGCAGTTTGAGGCATCTCTGCTGAACCTCTTCGACAAGGGCATCCTGGCC ACCCATGCCGTGCCCCAGCTGGAGAAGCTGGTGATGGAGGACATCTTCATCAGCGGTGACCCCCTGCTGGAGTCCGTGGGCCTTCATGAG CCACTGGTGGAAGAGCTACGGGCCACCATTGCCAGTGCCGTGTCCAAGGCCATGATCCCACTGCAGGCCTACGCCAAGGAGTACCGAAAG TACCTGGAGCTGAACAACAATGACATTGCCTCCTTTCTCAAAACCTACCAGACGCAGGGCCTGTTGGCCCAGGAGGTGCGGGAGGTAGTG CTCACCCACCTGCGGGAGAAGGAGATCCTGGACAGCTCGCTGCCCAGCAGCATCATCATTGGGCCTTTCTACATCAACACCGACAATGTC AAGCAGAGCCTGTCCAAGAAACGCAAGGCCCTGGCCACTTCCGTGCTGGACATCCTTGCCAAGAACCTGCATAAGGAGGTGGATAGCATC TGCGAGGAGTTCCGCAGCATCAGCCGCAAGATCTATGAGAAGCCCAACAGCATTGAGGAGCTGGCTGAGCTGCGAGAGTGGATGAAGGGC ATCCCGGAGAGGCTGGTGGGCCTGGAGGAGCGGATTGTGAAGGTCATGGATGACTACCAGGTCATGGATGAATTCCTCTACAACCTCAGC TCAGATGACTTCAATGACAAATGGATTGCCAGCAACTGGCCTTCTAAGATCCTTGGGCAGATAGAGCTGGTGCAGCAGCAGCATGTGGAG GATGAGGAGAAGTTCCGCAAAATCCAGATCATGGATCAGAACAACTTCCAAGAGAAGCTGGAAGGGCTGCAGCTGGTAGTAGCTGGCTTC TCCATCCATGTGGAGATTTCACGTGCACACGAGATCGCCAACGAGGTGCGGCGTGTCAAGAAGCAGCTGAAGGACTGCCAGCAGCTGGCC ATGCTCTACAACAACCGCGAGCGCATCTTCAGCTTGCCCATCACCAATTATGACAAGCTCTCCAGGATGGTGAAGGAGTTCCAACCCTAC CTGGACCTTTGGACCACAGCGTCTGACTGGCTGCGCTGGTCGGAGAGCTGGATGAATGACCCCCTCTCTGCCATCGATGCTGAGCAGCTG GAGAAGAACGTGGTTGAAGCCTTCAAGACCATGCACAAGTGCGTGAAGCAGTTTAAGGACATGCCAGCCTGCCAGGAAGTGGCCTTGGAC ATCCGGGCCCGCATCGAGGAGTTCAAACCATACATCCCACTGATCCAGGGGCTGCGCAACCCTGGCATGCGGATCCGGCACTGGGAGACA CTGTCCAACCAGATCAACATCAATGTCAGGCCCAAGGCCAACCTGACCTTTGCTCGCTGCCTGGAGATGAACCTGCAGGACCATATCGAG AGCATCAGCAAGGTGGCTGAGGTGGCTGGCAAGGAGTACGCCATCGAGCAGGCACTGGACAAGATGGAGAAGGAGTGGTCGACCATCCTG TTCAATGTACTGCCCTACAAGGCGACAGACACCTACATCCTGAAGAGCCCGGACGAGGCCTCACAGCTGCTGGACGACCACATCGTCATG ACCCAGAATATGTCATTTTCACCCTACAAGAAGCCCTTTGAGCAGCGCATCAACTCCTGGGAGAACAAACTGAAGCTGACCCAGGAGGTT CTGGAGGAGTGGCTGAACTGTCAGCGGTCCTGGCTCTACCTGGAGCCCATCTTTAGCTCTGAGGACATCAACCAGCAGCTGCCTGTGGAG AGCAAGCGCTACCAGACCATGGAGCGGATCTGGAAGAAGATCATGAAGAATGCCTACGAGAACCGGGAGGTGATCAATGTGTGTTCCGAC CTGAGAATGCTGGACAGCCTGCGGGACTGCAACAAGATTCTGGACCTGGTGCAGAAGGGCCTCAGCGAGTATCTGGAGACCAAGAGGAGC GCCTTCCCCAGGTTTTATGCCGCTGAGATAATGTGTGGACTGCAGTTTCTACACAGCAAGGGCATCATTTACAGGGACCTCAAACTGGAC AATGTGCTGCTGGACCGGGATGGCCACATCAAGATTGCCGACTTTGGGATGTGCAAAGAGAACATATTCGGGGAGAGCCGGGCCAGCACC TTCTGCGGCACCCCTGACTATATCGCCCCTGAGATCCTACAGGGCCTGAAGTACACATTCTCTGTGGACTGGTGGTCTTTCGGGGTCCTT CTGTACGAGATGCTCATTGGCCAGTCCCCCTTCCATGGTGATGATGAGGATGAACTCTTCGAGTCCATCCGTGTGGACACGCCACATTAT CCCCGCTGGATCACCAAGGAGTCCAAGGACATCCTGGAGAAGCTCTTTGAAAGGGAACCAACCAAGAGGCTGGGAGTGACCGGAAACATC AAAATCCACCCCTTCTTCAAGACCATAAACTGGACTCTGCTGGAAAAGCGGAGGTTGGAGCCACCTTTCAGGCCCAAAGTGAAGTCACCC AGAGACTACAGTAACTTTGACCAGGAGTTCCTGAACGAGAAGGCGCGCCTCTCCTACAGCGACAAGAACCTCATCGACTCCATGGACCAG TCTGCATTCGCTGGCTTCTCCTTTGTGAACCCCAAATTCGAGCACCTCCTGGAAGATTGAGGTTCCTGGACAGATCAGGCTAGCCCTGCC CTCCACCCACACCTGCCCGCTCCCCACGATAAGCACCAGTGGGACTGTGGTGACTTCTGCTGCTGGCCCCGCCCCTGCCCCCAGAGCGTC CTTGGCTGCCGTCTGGCCGGGCTCTCATGGTACTTCCTCTGTGAACTGTGTGTGAATCTGCTTTTCCTCTGCCTTCGGAGGGAAATTGTA AATCCTGTGTTTCATTACTTGAATGTAGTTATCTATTGAAAATATATATTATATACATAGACATATATATATATATAATAGGCTGTATAT ATTGCTCAGTAGAGAAAAACCATGGGGGACTGGTGATATGTTGATCTTTTTCAAAAAAATATATATATGACAAAAAAAAAAAAAAAGGAG >In-frame_DNAH1_ENST00000420323_chr3_52391751_+_PRKCD_ENST00000330452_chr3_53221356_+_5208nt GGGGGGTACCCAACCTATACGCAGACCCATTGAGCAGCCAGACTGCCCTAAACAGGGCTATGGAGTCCTTGTCCCTTCTAAGAGCTGTGG ACACCTTGCCTCCAGTTCCCCTCACAGTCCTTTCTTCCTTCTGCAGTGATCACTGAGTACCTGTGTGAATGCCAACAAGAAAAATAAAAC CACAGTTTGGATTCAGGAAAGGTTGCACCACCATCAGGTCTTGAAGGGAGCTTCGGCTGGGGCATCTCCCTGAGAAGCAGCATGGAGCAG CCTAACAGTAAAGGCTATAGCCTGGGAAGGACCCCTCAGGGCCCAGAGTGCAGCAGTGCTCCTGCAGTCCAAGTGGGGACCCACAGGGGC CTAGAGTATAACCCGGGGAAGATTCTTCCAGGATCAGACTATGGGTTGGGAAATCCTCCAGCCCTTGACCCCAAGCTCCCACATTTACCC CTGCCCCCGGCCCCACCCACACTCTCAGACTTGGGGCAGCCACGGAAGTCACCCCTGACAGGCACTGATAAGAAGTACCCGCTGATGAAG CAGCGTGGGTTCTACTCCGACATCCTCAGCCCTGGAACCTTAGATCAACTTGGGGAGGTATGTCGTGGCCCCCGAATGAGCCAGAACCTC CTGCGGCAGGCTGACCTTGACAAGTTCACCCCAAGAGTCGGAAGCTTTGAGGTTCCTGAAGACTTCCAGGAGCGCATGGAGCAGCAGTGC ATCGGGTCCACCACCCGGCTGCTCGCCCAGACTGACTTCCCACTGCAGGCCTACGAGCCCAAGATGCAGGTGCCTTTCCAGGTGCTGCCA GGCCAGCATCCTCGCAAGATTGAGATCGAGAGGAGGAAACAGCAGTACCTGAGCCTGGACATTGAGCAGTTGCTGTTCAGCCAGGGCATC GACTCCAACAAGCTCATGCCCAGGCACCTGGACCACCAGCACCCCCAAACCATCGAACAGGGCCATGACCCAATCTTCCCCATCTACCTC CCACTGAAGGTATTTGACAATGAGGACTTTGACTGCCGGACTCCCAGAGAGTGGATCAACATGGGCTTGGAGCCAGGGTCTCTGGACAGG AAACCTGTCCCGGGAAAAGCCCTCTTGCCCACTGATGACTTCCTGGGGCATGAGGACCCCAAGAGTCAGAAGCTGAAGTACAAATGGTGC GAGGTCGGCGTCCTGGACTACGACGAGGAGAAGAAGCTATACCTGGTACACAAGACAGACGAGAAAGGCCTGGTGCGAGATGAGATGGGG AGGCCCATCCTGAATGCAGGGGTCACCACTGAAGGAAGGCCACCCCTTCAGGTCTGTCAGTACTGGGTGCCACGGATCCAGCTTCTCTTC TGCGCTGAGGACCCTTGCATGTTCGCACAACGTGTGGTCCAGGCCAACGCCCTGCGCAAGAACACGGAAGCACTGCTGCTCTACAACTTG TATGTGGACTGCATGCCCTCTGACGGCCAGCATGTCATCAGTGAACAGAGCCTGAGCAAGATCAAGCAGTGGGCCCTGAGCACGCCTCGG ATGCGCAAAGGCCCCTCGGTTCTAGAGCACCTCAGCAGTCTTGCCAGAGAAGTGAGCCTGGACTATGAGCGCAGCATGAACAAGATCAAC TTTGACCACGTTGTCTCTTCCAAGCCCGAGACCTTCTCCTACGTCACCCTCCCCAAGAAGGAGGAGGAGCAGGTGCCTGAGCGAGGGCTG GTGAGTGTCCCCAAGTACCACTTCTGGGAGCAGAAGGAGGACTTCACTTTCGTGTCCCTGCTCACACGGCCAGAGGTCATCACGGCCCTC AGCAAGGTGAGGGCCGAGTGCAACAAGGTGACCGCCATGTCCCTGTTCCACTCGAGCCTCTCCAAGTACAGCCACCTGGAGGAATTTGAG CAGATCCAGTCACAGACCTTCTCCCAGGTGCAGATGTTCCTCAAGGACAGCTGGATCAGCTCGCTAAAGGTGGCCATGCGCAGCAGCCTG CGCGACATGAGCAAGGGCTGGTACAACCTCTACGAGACCAACTGGGAGGTGTACCTCATGTCCAAGCTGCGCAAGCTGATGGAGCTGGTG AAGTACATGCTGCAGGACACACTGCGCTTCCTGGTGCAGGACTCACTTGCCAGCTTCTCACAGTTCATCAGCGACACCTGTTGCAGCGTG CTCAACTGCACCGATGACATGGTCTGGGGTGACGACTTAATTAACAGCCCCTACAGGCCCCGGAAGAATCCCCTGTTCATCATGGACCTG GTGCTGGACAGCTCTGGGGTGCACTATAGCACCCCACTGGAGCAGTTTGAGGCATCTCTGCTGAACCTCTTCGACAAGGGCATCCTGGCC ACCCATGCCGTGCCCCAGCTGGAGAAGCTGGTGATGGAGGACATCTTCATCAGCGGTGACCCCCTGCTGGAGTCCGTGGGCCTTCATGAG CCACTGGTGGAAGAGCTACGGGCCACCATTGCCAGTGCCGTGTCCAAGGCCATGATCCCACTGCAGGCCTACGCCAAGGAGTACCGAAAG TACCTGGAGCTGAACAACAATGACATTGCCTCCTTTCTCAAAACCTACCAGACGCAGGGCCTGTTGGCCCAGGAGGTGCGGGAGGTAGTG CTCACCCACCTGCGGGAGAAGGAGATCCTGGACAGCTCGCTGCCCAGCAGCATCATCATTGGGCCTTTCTACATCAACACCGACAATGTC AAGCAGAGCCTGTCCAAGAAACGCAAGGCCCTGGCCACTTCCGTGCTGGACATCCTTGCCAAGAACCTGCATAAGGAGGTGGATAGCATC TGCGAGGAGTTCCGCAGCATCAGCCGCAAGATCTATGAGAAGCCCAACAGCATTGAGGAGCTGGCTGAGCTGCGAGAGTGGATGAAGGGC ATCCCGGAGAGGCTGGTGGGCCTGGAGGAGCGGATTGTGAAGGTCATGGATGACTACCAGGTCATGGATGAATTCCTCTACAACCTCAGC TCAGATGACTTCAATGACAAATGGATTGCCAGCAACTGGCCTTCTAAGATCCTTGGGCAGATAGAGCTGGTGCAGCAGCAGCATGTGGAG GATGAGGAGAAGTTCCGCAAAATCCAGATCATGGATCAGAACAACTTCCAAGAGAAGCTGGAAGGGCTGCAGCTGGTAGTAGCTGGCTTC TCCATCCATGTGGAGATTTCACGTGCACACGAGATCGCCAACGAGGTGCGGCGTGTCAAGAAGCAGCTGAAGGACTGCCAGCAGCTGGCC ATGCTCTACAACAACCGCGAGCGCATCTTCAGCTTGCCCATCACCAATTATGACAAGCTCTCCAGGATGGTGAAGGAGTTCCAACCCTAC CTGGACCTTTGGACCACAGCGTCTGACTGGCTGCGCTGGTCGGAGAGCTGGATGAATGACCCCCTCTCTGCCATCGATGCTGAGCAGCTG GAGAAGAACGTGGTTGAAGCCTTCAAGACCATGCACAAGTGCGTGAAGCAGTTTAAGGACATGCCAGCCTGCCAGGAAGTGGCCTTGGAC ATCCGGGCCCGCATCGAGGAGTTCAAACCATACATCCCACTGATCCAGGGGCTGCGCAACCCTGGCATGCGGATCCGGCACTGGGAGACA CTGTCCAACCAGATCAACATCAATGTCAGGCCCAAGGCCAACCTGACCTTTGCTCGCTGCCTGGAGATGAACCTGCAGGACCATATCGAG AGCATCAGCAAGGTGGCTGAGGTGGCTGGCAAGGAGTACGCCATCGAGCAGGCACTGGACAAGATGGAGAAGGAGTGGTCGACCATCCTG TTCAATGTACTGCCCTACAAGGCGACAGACACCTACATCCTGAAGAGCCCGGACGAGGCCTCACAGCTGCTGGACGACCACATCGTCATG ACCCAGAATATGTCATTTTCACCCTACAAGAAGCCCTTTGAGCAGCGCATCAACTCCTGGGAGAACAAACTGAAGCTGACCCAGGAGGTT CTGGAGGAGTGGCTGAACTGTCAGCGGTCCTGGCTCTACCTGGAGCCCATCTTTAGCTCTGAGGACATCAACCAGCAGCTGCCTGTGGAG AGCAAGCGCTACCAGACCATGGAGCGGATCTGGAAGAAGATCATGAAGAATGCCTACGAGAACCGGGAGGTGATCAATGTGTGTTCCGAC CTGAGAATGCTGGACAGCCTGCGGGACTGCAACAAGATTCTGGACCTGGTGCAGAAGGGCCTCAGCGAGTATCTGGAGACCAAGAGGAGC GCCTTCCCCAGGTTTTATGCCGCTGAGATAATGTGTGGACTGCAGTTTCTACACAGCAAGGGCATCATTTACAGGGACCTCAAACTGGAC AATGTGCTGCTGGACCGGGATGGCCACATCAAGATTGCCGACTTTGGGATGTGCAAAGAGAACATATTCGGGGAGAGCCGGGCCAGCACC TTCTGCGGCACCCCTGACTATATCGCCCCTGAGATCCTACAGGGCCTGAAGTACACATTCTCTGTGGACTGGTGGTCTTTCGGGGTCCTT CTGTACGAGATGCTCATTGGCCAGTCCCCCTTCCATGGTGATGATGAGGATGAACTCTTCGAGTCCATCCGTGTGGACACGCCACATTAT CCCCGCTGGATCACCAAGGAGTCCAAGGACATCCTGGAGAAGCTCTTTGAAAGGGAACCAACCAAGAGGCTGGGAGTGACCGGAAACATC AAAATCCACCCCTTCTTCAAGACCATAAACTGGACTCTGCTGGAAAAGCGGAGGTTGGAGCCACCTTTCAGGCCCAAAGTGAAGTCACCC AGAGACTACAGTAACTTTGACCAGGAGTTCCTGAACGAGAAGGCGCGCCTCTCCTACAGCGACAAGAACCTCATCGACTCCATGGACCAG TCTGCATTCGCTGGCTTCTCCTTTGTGAACCCCAAATTCGAGCACCTCCTGGAAGATTGAGGTTCCTGGACAGATCAGGCTAGCCCTGCC CTCCACCCACACCTGCCCGCTCCCCACGATAAGCACCAGTGGGACTGTGGTGACTTCTGCTGCTGGCCCCGCCCCTGCCCCCAGAGCGTC CTTGGCTGCCGTCTGGCCGGGCTCTCATGGTACTTCCTCTGTGAACTGTGTGTGAATCTGCTTTTCCTCTGCCTTCGGAGGGAAATTGTA |
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FusionGenePPI for DNAH1_PRKCD |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| DNAH1 | PRKCD | RASGRP3, PLSCR3, INPP5D, SHC1, RIPK4, YWHAG, PDPK1, C1QBP, GNA12, GNA13, MTOR, STAT1, PTK2B, ADAM9, INSR, PDP1, PDP2, PPP2CA, IRS1, PIK3CB, PTPN6, YWHAZ, TIAM1, PLD2, AFAP1, IL6ST, MUC1, GABRA1, CHUK, IKBKB, SP1, NFE2L2, PRKCD, HDAC5, STAT3, TRIM41, HSPB1, KLF4, VHL, HIST1H1A, TP53, IBTK, IRAK1, TRO, HIST1H1B, SNCA, NCF1, APP, ITGB2, TNFRSF1A, GSK3A, ELAVL1, PHB, SQSTM1, PRKCB, PRKCQ, DYNC1H1, HSPA4, HSP90AA1, ITPR1, MACF1, ART3, VCP, RANBP10, RANBP9, IL32, EP300, FLI1, DIABLO, PTGES3, MYC, DAB2, RPL37A, TKT, ZNF131, FXR1, DHX16, PRPF4B, PPRC1, CWC15, H2BFS, TRAPPC13, FAM192A, CHD9, BUD13, LYSMD2, ACTBL2, FYN, GRM5, NOTCH1, CARD11, TRAF6, MALT1, NGEF, TP73, MBP |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DNAH1_PRKCD |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | PRKCD | Q05655 | DB05013 | Ingenol Mebutate | Protein kinase C delta type | small molecule | approved |
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RelatedDiseases for DNAH1_PRKCD |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PRKCD | C0011853 | Diabetes Mellitus, Experimental | 1 | CTD_human |
| Tgene | PRKCD | C0020538 | Hypertensive disease | 1 | CTD_human |
| Tgene | PRKCD | C0021841 | Intestinal Neoplasms | 1 | CTD_human |
| Tgene | PRKCD | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | PRKCD | C0036572 | Seizures | 1 | CTD_human |
| Tgene | PRKCD | C0235032 | Neurotoxicity Syndromes | 1 | CTD_human |
| Tgene | PRKCD | C0242422 | Parkinsonian Disorders | 1 | CTD_human |
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