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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 10107

FusionGeneSummary for DLG5_RET

check button Fusion gene summary
Fusion gene informationFusion gene name: DLG5_RET
Fusion gene ID: 10107
HgeneTgene
Gene symbol

DLG5

RET

Gene ID

9231

5979

Gene namediscs large MAGUK scaffold protein 5ret proto-oncogene
SynonymsLP-DLG|P-DLG5|PDLGCDHF12|CDHR16|HSCR1|MEN2A|MEN2B|MTC1|PTC|RET-ELE1
Cytomap

10q22.3

10q11.21

Type of geneprotein-codingprotein-coding
Descriptiondisks large homolog 5discs large protein LP-DLGdiscs large protein P-dlgdiscs, large homolog 5large type of P-DLGplacenta and prostate DLGproto-oncogene tyrosine-protein kinase receptor RetRET receptor tyrosine kinasecadherin family member 12cadherin-related family member 16proto-oncogene c-Retrearranged during transfectionret proto-oncogene (multiple endocrine neoplasia and medullary
Modification date2018051920180527
UniProtAcc

Q8TDM6

P07949

Ensembl transtripts involved in fusion geneENST00000372391, ENST00000372388, 
ENST00000459739, 
ENST00000355710, 
ENST00000340058, 
Fusion gene scores* DoF score8 X 6 X 5=24018 X 10 X 7=1260
# samples 965
** MAII scorelog2(9/240*10)=-1.41503749927884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(65/1260*10)=-0.954912110471462
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DLG5 [Title/Abstract] AND RET [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Kinase involved fusion gene, inframe and retained kinase domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRET

GO:0030155

regulation of cell adhesion

21357690

TgeneRET

GO:0030335

positive regulation of cell migration

20702524

TgeneRET

GO:0033619

membrane protein proteolysis

21357690

TgeneRET

GO:0033630

positive regulation of cell adhesion mediated by integrin

20702524

TgeneRET

GO:0035860

glial cell-derived neurotrophic factor receptor signaling pathway

28953886

TgeneRET

GO:0043410

positive regulation of MAPK cascade

28846099


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVTHCATCGA-DE-A69K-01ADLG5chr10

79588640

-RETchr10

43612032

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000372391ENST00000355710DLG5chr10

79588640

-RETchr10

43612032

+
In-frameENST00000372391ENST00000340058DLG5chr10

79588640

-RETchr10

43612032

+
In-frameENST00000372388ENST00000355710DLG5chr10

79588640

-RETchr10

43612032

+
In-frameENST00000372388ENST00000340058DLG5chr10

79588640

-RETchr10

43612032

+
intron-3CDSENST00000459739ENST00000355710DLG5chr10

79588640

-RETchr10

43612032

+
intron-3CDSENST00000459739ENST00000340058DLG5chr10

79588640

-RETchr10

43612032

+

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FusionProtFeatures for DLG5_RET


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DLG5

Q8TDM6

RET

P07949

Receptor tyrosine-protein kinase involved in numerouscellular mechanisms including cell proliferation, neuronalnavigation, cell migration, and cell differentiation upon bindingwith glial cell derived neurotrophic factor family ligands.Phosphorylates PTK2/FAK1. Regulates both cell death/survivalbalance and positional information. Required for the molecularmechanisms orchestration during intestine organogenesis; involvedin the development of enteric nervous system and renalorganogenesis during embryonic life, and promotes the formation ofPeyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Modulates cell adhesion via itscleavage by caspase in sympathetic neurons and mediates cellmigration in an integrin (e.g. ITGB1 and ITGB3)-dependent manner.Involved in the development of the neural crest. Active in theabsence of ligand, triggering apoptosis through a mechanism thatrequires receptor intracellular caspase cleavage. Acts as adependence receptor; in the presence of the ligand GDNF insomatotrophs (within pituitary), promotes survival and downregulates growth hormone (GH) production, but triggers apoptosisin absence of GDNF. Regulates nociceptor survival and size.Triggers the differentiation of rapidly adapting (RA)mechanoreceptors. Mediator of several diseases such asneuroendocrine cancers; these diseases are characterized byaberrant integrins-regulated cell migration. Mediates, throughinteraction with GDF15-receptor GFRAL, GDF15-induced cell-signaling in the brainstem which induces inhibition of food-intake. Activates MAPK- and AKT-signaling pathways(PubMed:28846097, PubMed:28953886, PubMed:28846099). Isoform 1 incomplex with GFRAL induces higher activation of MAPK-signalingpathway than isoform 2 in complex with GFRAL (PubMed:28846099).{ECO:0000269|PubMed:20064382, ECO:0000269|PubMed:20616503,ECO:0000269|PubMed:20702524, ECO:0000269|PubMed:21357690,ECO:0000269|PubMed:21454698, ECO:0000269|PubMed:28846097,ECO:0000269|PubMed:28846099, ECO:0000269|PubMed:28953886}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDLG5chr10:79588640chr10:43612032ENST00000372388-1331383_5997631580Coiled coilOntology_term=ECO:0000255
HgeneDLG5chr10:79588640chr10:43612032ENST00000372391-1332383_5997631920Coiled coilOntology_term=ECO:0000255
HgeneDLG5chr10:79588640chr10:43612032ENST00000372388-1331113_1237631580Compositional biasNote=Poly-Ser
HgeneDLG5chr10:79588640chr10:43612032ENST00000372391-1332113_1237631920Compositional biasNote=Poly-Ser
HgeneDLG5chr10:79588640chr10:43612032ENST00000372388-1331620_7107631580DomainPDZ 1
HgeneDLG5chr10:79588640chr10:43612032ENST00000372391-1332620_7107631920DomainPDZ 1
TgeneRETchr10:79588640chr10:43612032ENST00000340058+1019724_10167121073DomainProtein kinase
TgeneRETchr10:79588640chr10:43612032ENST00000355710+1020724_10167121115DomainProtein kinase
TgeneRETchr10:79588640chr10:43612032ENST00000340058+1019730_7387121073Nucleotide bindingATP
TgeneRETchr10:79588640chr10:43612032ENST00000355710+1020730_7387121115Nucleotide bindingATP
TgeneRETchr10:79588640chr10:43612032ENST00000340058+1019805_8077121073RegionNote=Inhibitors binding
TgeneRETchr10:79588640chr10:43612032ENST00000355710+1020805_8077121115RegionNote=Inhibitors binding

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDLG5chr10:79588640chr10:43612032ENST00000372388-1331982_10667631580Compositional biasNote=Pro-rich
HgeneDLG5chr10:79588640chr10:43612032ENST00000372391-1332982_10667631920Compositional biasNote=Pro-rich
HgeneDLG5chr10:79588640chr10:43612032ENST00000372388-13311350_14297631580DomainPDZ 3
HgeneDLG5chr10:79588640chr10:43612032ENST00000372388-13311501_15827631580DomainPDZ 4
HgeneDLG5chr10:79588640chr10:43612032ENST00000372388-13311593_16617631580DomainSH3
HgeneDLG5chr10:79588640chr10:43612032ENST00000372388-13311722_19057631580DomainGuanylate kinase-like
HgeneDLG5chr10:79588640chr10:43612032ENST00000372388-1331705_7967631580DomainPDZ 2
HgeneDLG5chr10:79588640chr10:43612032ENST00000372391-13321350_14297631920DomainPDZ 3
HgeneDLG5chr10:79588640chr10:43612032ENST00000372391-13321501_15827631920DomainPDZ 4
HgeneDLG5chr10:79588640chr10:43612032ENST00000372391-13321593_16617631920DomainSH3
HgeneDLG5chr10:79588640chr10:43612032ENST00000372391-13321722_19057631920DomainGuanylate kinase-like
HgeneDLG5chr10:79588640chr10:43612032ENST00000372391-1332705_7967631920DomainPDZ 2
TgeneRETchr10:79588640chr10:43612032ENST00000340058+1019168_2727121073DomainCadherin
TgeneRETchr10:79588640chr10:43612032ENST00000355710+1020168_2727121115DomainCadherin
TgeneRETchr10:79588640chr10:43612032ENST00000340058+101929_6357121073Topological domainExtracellular
TgeneRETchr10:79588640chr10:43612032ENST00000340058+1019658_11147121073Topological domainCytoplasmic
TgeneRETchr10:79588640chr10:43612032ENST00000355710+102029_6357121115Topological domainExtracellular
TgeneRETchr10:79588640chr10:43612032ENST00000355710+1020658_11147121115Topological domainCytoplasmic
TgeneRETchr10:79588640chr10:43612032ENST00000340058+1019636_6577121073TransmembraneHelical
TgeneRETchr10:79588640chr10:43612032ENST00000355710+1020636_6577121115TransmembraneHelical


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FusionGeneSequence for DLG5_RET


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_1166aa
MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLLLAKERDHFQDLRAALEKTQPHLLPILYLNG
VVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP
YHRLNPDTERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKR
LHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLTDTAMDKLEVVKKDTDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD
TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQ
TEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI
RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDI
DLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL
HINLSGQKDSGISLENGVTAAAVLPGSPAAKEGSLAVGDRIVAEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKM
LKENASPSELRDLLSEFNVLKQVNHPHVIKLTGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG
DLISFAWQISQGMQTLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVTEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGV
LLWEIVTLGGNPTPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIT

>In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_1124aa
MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLLLAKERDHFQDLRAALEKTQPHLLPILYLNG
VVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP
YHRLNPDTERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKR
LHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLTDTAMDKLEVVKKDTDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD
TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQ
TEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI
RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDI
DLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL
HINLSGQKDSGISLENGVTAAAVLPGSPAAKEGSLAVGDRIVAEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKM
LKENASPSELRDLLSEFNVLKQVNHPHVIKLTGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG
DLISFAWQISQGMQTLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVTEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGV
LLWEIVTLGGNPTPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIT

>In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_1166aa
MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLLLAKERDHFQDLRAALEKTQPHLLPILYLNG
VVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP
YHRLNPDTERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKR
LHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLTDTAMDKLEVVKKDTDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD
TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQ
TEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI
RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDI
DLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL
HINLSGQKDSGISLENGVTAAAVLPGSPAAKEGSLAVGDRIVAEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKM
LKENASPSELRDLLSEFNVLKQVNHPHVIKLTGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG
DLISFAWQISQGMQTLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVTEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGV
LLWEIVTLGGNPTPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIT

>In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_1124aa
MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLLLAKERDHFQDLRAALEKTQPHLLPILYLNG
VVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP
YHRLNPDTERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKR
LHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLTDTAMDKLEVVKKDTDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD
TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQ
TEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI
RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDI
DLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL
HINLSGQKDSGISLENGVTAAAVLPGSPAAKEGSLAVGDRIVAEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKM
LKENASPSELRDLLSEFNVLKQVNHPHVIKLTGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG
DLISFAWQISQGMQTLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVTEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGV
LLWEIVTLGGNPTPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIT


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_3498nt
ATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGGCTGCTC
GAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAGCTGCTC
TTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTGAACGGC
GTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGCAGCTCC
CTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAACCTCTCC
ATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAGAGGCCC
TACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAGCACACC
AACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACTCGGCTG
AAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATGAAGCGG
CTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATTCTCAAC
AAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTCGCCATC
CACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAGAGGGAC
ACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCGCAGAAC
AAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCGGAGAAA
TACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAGCTGCAG
ACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGGCAGATC
AAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAGCTGAAG
GAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGACAGCATC
CGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACCCGCAAG
CAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAGCTGATG
GCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAGGATATT
GACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAAGTGGAC
AAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAGAAGCAG
GCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACGCCGCTG
CACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCTGCCGCT
AAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACT
CTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATG
CTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAA
TTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGC
CGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGC
GACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAAC
ATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGC
CAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTC
CTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGG
ATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCG
GACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTAT
GACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAAC
AAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGA

>In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_3372nt
ATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGGCTGCTC
GAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAGCTGCTC
TTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTGAACGGC
GTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGCAGCTCC
CTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAACCTCTCC
ATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAGAGGCCC
TACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAGCACACC
AACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACTCGGCTG
AAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATGAAGCGG
CTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATTCTCAAC
AAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTCGCCATC
CACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAGAGGGAC
ACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCGCAGAAC
AAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCGGAGAAA
TACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAGCTGCAG
ACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGGCAGATC
AAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAGCTGAAG
GAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGACAGCATC
CGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACCCGCAAG
CAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAGCTGATG
GCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAGGATATT
GACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAAGTGGAC
AAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAGAAGCAG
GCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACGCCGCTG
CACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCTGCCGCT
AAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACT
CTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATG
CTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAA
TTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGC
CGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGC
GACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAAC
ATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGC
CAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTC
CTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGG
ATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCG
GACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTAT
GACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAAC

>In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_3498nt
ATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGGCTGCTC
GAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAGCTGCTC
TTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTGAACGGC
GTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGCAGCTCC
CTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAACCTCTCC
ATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAGAGGCCC
TACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAGCACACC
AACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACTCGGCTG
AAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATGAAGCGG
CTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATTCTCAAC
AAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTCGCCATC
CACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAGAGGGAC
ACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCGCAGAAC
AAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCGGAGAAA
TACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAGCTGCAG
ACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGGCAGATC
AAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAGCTGAAG
GAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGACAGCATC
CGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACCCGCAAG
CAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAGCTGATG
GCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAGGATATT
GACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAAGTGGAC
AAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAGAAGCAG
GCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACGCCGCTG
CACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCTGCCGCT
AAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACT
CTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATG
CTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAA
TTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGC
CGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGC
GACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAAC
ATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGC
CAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTC
CTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGG
ATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCG
GACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTAT
GACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAAC
AAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGA

>In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_3372nt
ATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGGCTGCTC
GAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAGCTGCTC
TTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTGAACGGC
GTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGCAGCTCC
CTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAACCTCTCC
ATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAGAGGCCC
TACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAGCACACC
AACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACTCGGCTG
AAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATGAAGCGG
CTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATTCTCAAC
AAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTCGCCATC
CACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAGAGGGAC
ACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCGCAGAAC
AAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCGGAGAAA
TACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAGCTGCAG
ACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGGCAGATC
AAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAGCTGAAG
GAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGACAGCATC
CGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACCCGCAAG
CAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAGCTGATG
GCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAGGATATT
GACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAAGTGGAC
AAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAGAAGCAG
GCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACGCCGCTG
CACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCTGCCGCT
AAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACT
CTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATG
CTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAA
TTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGC
CGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGC
GACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAAC
ATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGC
CAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTC
CTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGG
ATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCG
GACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTAT
GACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAAC


* Fusion transcript sequences (Full-length transcript).
>In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_5586nt
GCCACCATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGG
CTGCTCGAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAG
CTGCTCTTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTG
AACGGCGTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGC
AGCTCCCTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAAC
CTCTCCATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAG
AGGCCCTACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAG
CACACCAACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACT
CGGCTGAAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATG
AAGCGGCTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATT
CTCAACAAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTC
GCCATCCACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAG
AGGGACACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCG
CAGAACAAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCG
GAGAAATACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAG
CTGCAGACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGG
CAGATCAAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAG
CTGAAGGAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGAC
AGCATCCGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACC
CGCAAGCAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAG
CTGATGGCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAG
GATATTGACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAA
GTGGACAAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAG
AAGCAGGCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACG
CCGCTGCACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCT
GCCGCTAAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGA
AAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTG
AAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTC
ATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGC
GAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACC
ATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCC
AGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAG
AGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTT
GGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGC
CACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTG
TTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTG
ATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATT
GAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTT
CCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTC
TTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCG
AGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTC
CCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGT
TGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAAC
TGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCC
CTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGG
CCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTT
TCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGG
CTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGA
AGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCA
CAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTA
CTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGA
AAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATG
TTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCA
GTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCA
AAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAA
ACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAG
TTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATA
GACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAAT
GCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAA
TTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAAT
TTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCT
ATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCATGTATC

>In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_4128nt
GCCACCATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGG
CTGCTCGAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAG
CTGCTCTTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTG
AACGGCGTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGC
AGCTCCCTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAAC
CTCTCCATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAG
AGGCCCTACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAG
CACACCAACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACT
CGGCTGAAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATG
AAGCGGCTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATT
CTCAACAAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTC
GCCATCCACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAG
AGGGACACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCG
CAGAACAAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCG
GAGAAATACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAG
CTGCAGACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGG
CAGATCAAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAG
CTGAAGGAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGAC
AGCATCCGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACC
CGCAAGCAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAG
CTGATGGCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAG
GATATTGACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAA
GTGGACAAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAG
AAGCAGGCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACG
CCGCTGCACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCT
GCCGCTAAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGA
AAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTG
AAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTC
ATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGC
GAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACC
ATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCC
AGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAG
AGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTT
GGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGC
CACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTG
TTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTG
ATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATT
GAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCT
TTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTT
AGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAA
ACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTT
AACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCA
GGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGT
CCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCT
TTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTG

>In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_5680nt
CGGCGCCCTAGGGCTGCTGCCGAGGTGCTCGCCTGCCCGCCCGCCGGCCTCGGGGGGCCCGGGAGGCGTCCGGCGGGGCGGGGCGGCGCG
GCCCGCCACCATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCT
CGGGCTGCTCGAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCT
CAAGCTGCTCTTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTA
CCTGAACGGCGTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAG
CAGCAGCTCCCTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGA
GAACCTCTCCATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGA
CAAGAGGCCCTACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAA
CCAGCACACCAACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCA
GACTCGGCTGAAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGA
CATGAAGCGGCTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGA
GATTCTCAACAAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAA
AGTCGCCATCCACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCA
GCAGAGGGACACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCAC
GGCGCAGAACAAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGA
GTCGGAGAAATACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGA
CAAGCTGCAGACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCT
GCGGCAGATCAAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCA
GGAGCTGAAGGAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCG
TGACAGCATCCGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGA
CACCCGCAAGCAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCG
ACAGCTGATGGCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGAC
GGAGGATATTGACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCAC
TAAAGTGGACAAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGA
CAAGAAGCAGGCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGT
CACGCCGCTGCACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAG
CCCTGCCGCTAAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCT
TGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGC
CGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACA
TGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCT
CCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCT
CACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGC
AGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGT
GAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTC
TTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGAC
CGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCC
GGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTC
CCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATG
GATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGG
GTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACA
TTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTG
GCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGAT
TTTCCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCA
GTGTTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCT
GAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCT
GGCCCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGA
GGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTG
GTTTTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAG
AGGGCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGT
ATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACAC
CCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAA
CTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGAT
GTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAA
GATGTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCC
TCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATT
ACCAAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCAC
AAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGG
AGAGTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATC
TATAGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAA
AAATGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGG
GGAATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTG
GAATTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAA
ATCTATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCATG

>In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_4222nt
CGGCGCCCTAGGGCTGCTGCCGAGGTGCTCGCCTGCCCGCCCGCCGGCCTCGGGGGGCCCGGGAGGCGTCCGGCGGGGCGGGGCGGCGCG
GCCCGCCACCATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCT
CGGGCTGCTCGAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCT
CAAGCTGCTCTTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTA
CCTGAACGGCGTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAG
CAGCAGCTCCCTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGA
GAACCTCTCCATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGA
CAAGAGGCCCTACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAA
CCAGCACACCAACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCA
GACTCGGCTGAAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGA
CATGAAGCGGCTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGA
GATTCTCAACAAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAA
AGTCGCCATCCACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCA
GCAGAGGGACACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCAC
GGCGCAGAACAAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGA
GTCGGAGAAATACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGA
CAAGCTGCAGACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCT
GCGGCAGATCAAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCA
GGAGCTGAAGGAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCG
TGACAGCATCCGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGA
CACCCGCAAGCAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCG
ACAGCTGATGGCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGAC
GGAGGATATTGACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCAC
TAAAGTGGACAAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGA
CAAGAAGCAGGCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGT
CACGCCGCTGCACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAG
CCCTGCCGCTAAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCT
TGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGC
CGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACA
TGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCT
CCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCT
CACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGC
AGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGT
GAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTC
TTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGAC
CGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCC
GGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTC
CCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATG
GATTGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGA
TGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTAC
ATTTAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGA
AAAAACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTA
CTTTAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACA
GCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCC
CAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACA
TCCTTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGT


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FusionGenePPI for DLG5_RET


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
DLG5SORBS3, CTNNB1, CD81, BTBD10, TERF1, DLST, PFN1, UBC, CUL3, BAG5, MARK3, TPM1, BTRC, MED4, CEP104, CEP152, CEP128, CEP135, CEP89, CNTRL, NINL, ODF2, SASS6, RPGRIP1, CDK1, MARK2, FGFR1OP, GAN, CDH1RETSTAT3, DOK6, DOK5, SRC, SHC1, PTPRF, DOK2, DOK4, DOK1, GRB2, CRK, PLCG1, PDLIM7, GRB7, FRS2, NRTN, GFRA1, GRB10, IKBKG, MCRS1, CBL, CBLC, RET, HSP90AA1, NOTCH2NL, NOTCH3, AIP, EGFR, NTRK1, ZBTB48, HNRNPD, SORT1, SYNCRIP, SGTB, BAG6, HIST1H3A, KYNU, TXNL4A, ZCCHC8, ICE2, MAPK3, PTK2, MAPK1, PTPRR, DUSP26


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for DLG5_RET


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneRETP07949DB05294VandetanibProto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305}small moleculeapproved
TgeneRETP07949DB08896RegorafenibProto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305}small moleculeapproved
TgeneRETP07949DB00398SorafenibProto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305}small moleculeapproved|investigational
TgeneRETP07949DB08875CabozantinibProto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305}small moleculeapproved|investigational
TgeneRETP07949DB08901PonatinibProto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305}small moleculeapproved|investigational

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RelatedDiseases for DLG5_RET


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneRETC3888239HIRSCHSPRUNG DISEASE, SUSCEPTIBILITY TO, 115UNIPROT
TgeneRETC0025268Multiple Endocrine Neoplasia Type 2a14CTD_human;ORPHANET;UNIPROT
TgeneRETC1833921Familial medullary thyroid carcinoma14CTD_human;ORPHANET;UNIPROT
TgeneRETC0025269Multiple Endocrine Neoplasia Type 2b8CTD_human;ORPHANET;UNIPROT
TgeneRETC1275808Congenital central hypoventilation4CTD_human;ORPHANET;UNIPROT
TgeneRETC0009404Colorectal Neoplasms2CTD_human
TgeneRETC0019569Hirschsprung Disease2CTD_human;HPO;ORPHANET
TgeneRETC0006413Burkitt Lymphoma1CTD_human
TgeneRETC0027662Multiple Endocrine Neoplasia1CTD_human
TgeneRETC0031511Pheochromocytoma1CTD_human;HPO;UNIPROT
TgeneRETC0038220Status Epilepticus1CTD_human
TgeneRETC0040136Thyroid Neoplasm1CTD_human
TgeneRETC0206693Medullary carcinoma1CTD_human
TgeneRETC0238462Medullary carcinoma of thyroid1CTD_human;HPO
TgeneRETC0740340Amyloidosis, Familial1CTD_human
TgeneRETC1609433Congenital absence of kidneys syndrome1CTD_human;ORPHANET