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Fusion gene ID: 10107 |
FusionGeneSummary for DLG5_RET |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DLG5_RET | Fusion gene ID: 10107 | Hgene | Tgene | Gene symbol | DLG5 | RET | Gene ID | 9231 | 5979 |
| Gene name | discs large MAGUK scaffold protein 5 | ret proto-oncogene | |
| Synonyms | LP-DLG|P-DLG5|PDLG | CDHF12|CDHR16|HSCR1|MEN2A|MEN2B|MTC1|PTC|RET-ELE1 | |
| Cytomap | 10q22.3 | 10q11.21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | disks large homolog 5discs large protein LP-DLGdiscs large protein P-dlgdiscs, large homolog 5large type of P-DLGplacenta and prostate DLG | proto-oncogene tyrosine-protein kinase receptor RetRET receptor tyrosine kinasecadherin family member 12cadherin-related family member 16proto-oncogene c-Retrearranged during transfectionret proto-oncogene (multiple endocrine neoplasia and medullary | |
| Modification date | 20180519 | 20180527 | |
| UniProtAcc | Q8TDM6 | P07949 | |
| Ensembl transtripts involved in fusion gene | ENST00000372391, ENST00000372388, ENST00000459739, | ENST00000355710, ENST00000340058, | |
| Fusion gene scores | * DoF score | 8 X 6 X 5=240 | 18 X 10 X 7=1260 |
| # samples | 9 | 65 | |
| ** MAII score | log2(9/240*10)=-1.41503749927884 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(65/1260*10)=-0.954912110471462 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DLG5 [Title/Abstract] AND RET [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | RET | GO:0030155 | regulation of cell adhesion | 21357690 |
| Tgene | RET | GO:0030335 | positive regulation of cell migration | 20702524 |
| Tgene | RET | GO:0033619 | membrane protein proteolysis | 21357690 |
| Tgene | RET | GO:0033630 | positive regulation of cell adhesion mediated by integrin | 20702524 |
| Tgene | RET | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway | 28953886 |
| Tgene | RET | GO:0043410 | positive regulation of MAPK cascade | 28846099 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | THCA | TCGA-DE-A69K-01A | DLG5 | chr10 | 79588640 | - | RET | chr10 | 43612032 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000372391 | ENST00000355710 | DLG5 | chr10 | 79588640 | - | RET | chr10 | 43612032 | + |
| In-frame | ENST00000372391 | ENST00000340058 | DLG5 | chr10 | 79588640 | - | RET | chr10 | 43612032 | + |
| In-frame | ENST00000372388 | ENST00000355710 | DLG5 | chr10 | 79588640 | - | RET | chr10 | 43612032 | + |
| In-frame | ENST00000372388 | ENST00000340058 | DLG5 | chr10 | 79588640 | - | RET | chr10 | 43612032 | + |
| intron-3CDS | ENST00000459739 | ENST00000355710 | DLG5 | chr10 | 79588640 | - | RET | chr10 | 43612032 | + |
| intron-3CDS | ENST00000459739 | ENST00000340058 | DLG5 | chr10 | 79588640 | - | RET | chr10 | 43612032 | + |
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FusionProtFeatures for DLG5_RET |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DLG5 | RET |
| Receptor tyrosine-protein kinase involved in numerouscellular mechanisms including cell proliferation, neuronalnavigation, cell migration, and cell differentiation upon bindingwith glial cell derived neurotrophic factor family ligands.Phosphorylates PTK2/FAK1. Regulates both cell death/survivalbalance and positional information. Required for the molecularmechanisms orchestration during intestine organogenesis; involvedin the development of enteric nervous system and renalorganogenesis during embryonic life, and promotes the formation ofPeyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Modulates cell adhesion via itscleavage by caspase in sympathetic neurons and mediates cellmigration in an integrin (e.g. ITGB1 and ITGB3)-dependent manner.Involved in the development of the neural crest. Active in theabsence of ligand, triggering apoptosis through a mechanism thatrequires receptor intracellular caspase cleavage. Acts as adependence receptor; in the presence of the ligand GDNF insomatotrophs (within pituitary), promotes survival and downregulates growth hormone (GH) production, but triggers apoptosisin absence of GDNF. Regulates nociceptor survival and size.Triggers the differentiation of rapidly adapting (RA)mechanoreceptors. Mediator of several diseases such asneuroendocrine cancers; these diseases are characterized byaberrant integrins-regulated cell migration. Mediates, throughinteraction with GDF15-receptor GFRAL, GDF15-induced cell-signaling in the brainstem which induces inhibition of food-intake. Activates MAPK- and AKT-signaling pathways(PubMed:28846097, PubMed:28953886, PubMed:28846099). Isoform 1 incomplex with GFRAL induces higher activation of MAPK-signalingpathway than isoform 2 in complex with GFRAL (PubMed:28846099).{ECO:0000269|PubMed:20064382, ECO:0000269|PubMed:20616503,ECO:0000269|PubMed:20702524, ECO:0000269|PubMed:21357690,ECO:0000269|PubMed:21454698, ECO:0000269|PubMed:28846097,ECO:0000269|PubMed:28846099, ECO:0000269|PubMed:28953886}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372388 | - | 13 | 31 | 383_599 | 763 | 1580 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372391 | - | 13 | 32 | 383_599 | 763 | 1920 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372388 | - | 13 | 31 | 113_123 | 763 | 1580 | Compositional bias | Note=Poly-Ser |
| Hgene | DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372391 | - | 13 | 32 | 113_123 | 763 | 1920 | Compositional bias | Note=Poly-Ser |
| Hgene | DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372388 | - | 13 | 31 | 620_710 | 763 | 1580 | Domain | PDZ 1 |
| Hgene | DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372391 | - | 13 | 32 | 620_710 | 763 | 1920 | Domain | PDZ 1 |
| Tgene | >RET | chr10:79588640 | chr10:43612032 | ENST00000340058 | + | 10 | 19 | 724_1016 | 712 | 1073 | Domain | Protein kinase |
| Tgene | >RET | chr10:79588640 | chr10:43612032 | ENST00000355710 | + | 10 | 20 | 724_1016 | 712 | 1115 | Domain | Protein kinase |
| Tgene | >RET | chr10:79588640 | chr10:43612032 | ENST00000340058 | + | 10 | 19 | 730_738 | 712 | 1073 | Nucleotide binding | ATP |
| Tgene | >RET | chr10:79588640 | chr10:43612032 | ENST00000355710 | + | 10 | 20 | 730_738 | 712 | 1115 | Nucleotide binding | ATP |
| Tgene | >RET | chr10:79588640 | chr10:43612032 | ENST00000340058 | + | 10 | 19 | 805_807 | 712 | 1073 | Region | Note=Inhibitors binding |
| Tgene | >RET | chr10:79588640 | chr10:43612032 | ENST00000355710 | + | 10 | 20 | 805_807 | 712 | 1115 | Region | Note=Inhibitors binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372388 | - | 13 | 31 | 982_1066 | 763 | 1580 | Compositional bias | Note=Pro-rich |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372391 | - | 13 | 32 | 982_1066 | 763 | 1920 | Compositional bias | Note=Pro-rich |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372388 | - | 13 | 31 | 1350_1429 | 763 | 1580 | Domain | PDZ 3 |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372388 | - | 13 | 31 | 1501_1582 | 763 | 1580 | Domain | PDZ 4 |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372388 | - | 13 | 31 | 1593_1661 | 763 | 1580 | Domain | SH3 |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372388 | - | 13 | 31 | 1722_1905 | 763 | 1580 | Domain | Guanylate kinase-like |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372388 | - | 13 | 31 | 705_796 | 763 | 1580 | Domain | PDZ 2 |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372391 | - | 13 | 32 | 1350_1429 | 763 | 1920 | Domain | PDZ 3 |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372391 | - | 13 | 32 | 1501_1582 | 763 | 1920 | Domain | PDZ 4 |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372391 | - | 13 | 32 | 1593_1661 | 763 | 1920 | Domain | SH3 |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372391 | - | 13 | 32 | 1722_1905 | 763 | 1920 | Domain | Guanylate kinase-like |
| Hgene | >DLG5 | chr10:79588640 | chr10:43612032 | ENST00000372391 | - | 13 | 32 | 705_796 | 763 | 1920 | Domain | PDZ 2 |
| Tgene | RET | chr10:79588640 | chr10:43612032 | ENST00000340058 | + | 10 | 19 | 168_272 | 712 | 1073 | Domain | Cadherin |
| Tgene | RET | chr10:79588640 | chr10:43612032 | ENST00000355710 | + | 10 | 20 | 168_272 | 712 | 1115 | Domain | Cadherin |
| Tgene | RET | chr10:79588640 | chr10:43612032 | ENST00000340058 | + | 10 | 19 | 29_635 | 712 | 1073 | Topological domain | Extracellular |
| Tgene | RET | chr10:79588640 | chr10:43612032 | ENST00000340058 | + | 10 | 19 | 658_1114 | 712 | 1073 | Topological domain | Cytoplasmic |
| Tgene | RET | chr10:79588640 | chr10:43612032 | ENST00000355710 | + | 10 | 20 | 29_635 | 712 | 1115 | Topological domain | Extracellular |
| Tgene | RET | chr10:79588640 | chr10:43612032 | ENST00000355710 | + | 10 | 20 | 658_1114 | 712 | 1115 | Topological domain | Cytoplasmic |
| Tgene | RET | chr10:79588640 | chr10:43612032 | ENST00000340058 | + | 10 | 19 | 636_657 | 712 | 1073 | Transmembrane | Helical |
| Tgene | RET | chr10:79588640 | chr10:43612032 | ENST00000355710 | + | 10 | 20 | 636_657 | 712 | 1115 | Transmembrane | Helical |
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FusionGeneSequence for DLG5_RET |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_1166aa MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLLLAKERDHFQDLRAALEKTQPHLLPILYLNG VVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP YHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKR LHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQ TEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDI DLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL HINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKM LKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGV LLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIY >In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_1124aa MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLLLAKERDHFQDLRAALEKTQPHLLPILYLNG VVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP YHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKR LHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQ TEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDI DLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL HINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKM LKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGV LLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIY >In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_1166aa MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLLLAKERDHFQDLRAALEKTQPHLLPILYLNG VVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP YHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKR LHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQ TEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDI DLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL HINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKM LKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGV LLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIY >In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_1124aa MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGGAKAELLLKLLLAKERDHFQDLRAALEKTQPHLLPILYLNG VVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDKRP YHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKR LHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRD TAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQ TEVELAESKLKSSTSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSI RTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDI DLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPL HINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKM LKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGV LLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIY |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_3498nt ATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGGCTGCTC GAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAGCTGCTC TTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTGAACGGC GTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGCAGCTCC CTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAACCTCTCC ATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAGAGGCCC TACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAGCACACC AACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACTCGGCTG AAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATGAAGCGG CTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATTCTCAAC AAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTCGCCATC CACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAGAGGGAC ACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCGCAGAAC AAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCGGAGAAA TACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAGCTGCAG ACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGGCAGATC AAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAGCTGAAG GAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGACAGCATC CGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACCCGCAAG CAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAGCTGATG GCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAGGATATT GACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAAGTGGAC AAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAGAAGCAG GCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACGCCGCTG CACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCTGCCGCT AAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACT CTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATG CTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAA TTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGC CGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGC GACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAAC ATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGC CAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTC CTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGG ATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCG GACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTAT GACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAAC AAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGA >In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_3372nt ATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGGCTGCTC GAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAGCTGCTC TTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTGAACGGC GTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGCAGCTCC CTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAACCTCTCC ATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAGAGGCCC TACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAGCACACC AACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACTCGGCTG AAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATGAAGCGG CTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATTCTCAAC AAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTCGCCATC CACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAGAGGGAC ACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCGCAGAAC AAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCGGAGAAA TACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAGCTGCAG ACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGGCAGATC AAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAGCTGAAG GAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGACAGCATC CGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACCCGCAAG CAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAGCTGATG GCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAGGATATT GACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAAGTGGAC AAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAGAAGCAG GCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACGCCGCTG CACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCTGCCGCT AAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACT CTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATG CTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAA TTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGC CGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGC GACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAAC ATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGC CAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTC CTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGG ATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCG GACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTAT GACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAAC >In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_3498nt ATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGGCTGCTC GAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAGCTGCTC TTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTGAACGGC GTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGCAGCTCC CTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAACCTCTCC ATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAGAGGCCC TACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAGCACACC AACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACTCGGCTG AAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATGAAGCGG CTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATTCTCAAC AAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTCGCCATC CACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAGAGGGAC ACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCGCAGAAC AAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCGGAGAAA TACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAGCTGCAG ACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGGCAGATC AAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAGCTGAAG GAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGACAGCATC CGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACCCGCAAG CAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAGCTGATG GCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAGGATATT GACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAAGTGGAC AAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAGAAGCAG GCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACGCCGCTG CACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCTGCCGCT AAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACT CTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATG CTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAA TTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGC CGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGC GACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAAC ATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGC CAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTC CTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGG ATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCG GACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTAT GACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAAC AAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGA >In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_3372nt ATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGGCTGCTC GAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAGCTGCTC TTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTGAACGGC GTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGCAGCTCC CTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAACCTCTCC ATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAGAGGCCC TACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAGCACACC AACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACTCGGCTG AAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATGAAGCGG CTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATTCTCAAC AAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTCGCCATC CACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAGAGGGAC ACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCGCAGAAC AAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCGGAGAAA TACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAGCTGCAG ACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGGCAGATC AAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAGCTGAAG GAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGACAGCATC CGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACCCGCAAG CAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAGCTGATG GCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAGGATATT GACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAAGTGGAC AAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAGAAGCAG GCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACGCCGCTG CACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCTGCCGCT AAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACT CTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATG CTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAA TTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGC CGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGC GACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAAC ATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGC CAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTC CTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGG ATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCG GACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTAT GACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_5586nt GCCACCATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGG CTGCTCGAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAG CTGCTCTTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTG AACGGCGTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGC AGCTCCCTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAAC CTCTCCATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAG AGGCCCTACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAG CACACCAACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACT CGGCTGAAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATG AAGCGGCTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATT CTCAACAAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTC GCCATCCACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAG AGGGACACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCG CAGAACAAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCG GAGAAATACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAG CTGCAGACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGG CAGATCAAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAG CTGAAGGAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGAC AGCATCCGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACC CGCAAGCAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAG CTGATGGCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAG GATATTGACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAA GTGGACAAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAG AAGCAGGCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACG CCGCTGCACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCT GCCGCTAAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGA AAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTG AAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTC ATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGC GAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACC ATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCC AGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAG AGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTT GGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGC CACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTG TTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTG ATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATT GAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTT CCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTC TTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCG AGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTC CCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGT TGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAAC TGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCC CTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGG CCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTT TCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGG CTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGA AGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCA CAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTA CTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGA AAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATG TTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCA GTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCA AAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAA ACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAG TTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATA GACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAAT GCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAA TTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAAT TTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCT ATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCATGTATC >In-frame_DLG5_ENST00000372391_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_4128nt GCCACCATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCTCGGG CTGCTCGAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAG CTGCTCTTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTACCTG AACGGCGTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAGCAGC AGCTCCCTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGAGAAC CTCTCCATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGACAAG AGGCCCTACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAACCAG CACACCAACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCAGACT CGGCTGAAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGACATG AAGCGGCTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGAGATT CTCAACAAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAAAGTC GCCATCCACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCAGCAG AGGGACACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCACGGCG CAGAACAAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGAGTCG GAGAAATACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGACAAG CTGCAGACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGG CAGATCAAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCAGGAG CTGAAGGAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCGTGAC AGCATCCGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGACACC CGCAAGCAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAG CTGATGGCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGACGGAG GATATTGACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCACTAAA GTGGACAAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGACAAG AAGCAGGCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACG CCGCTGCACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAGCCCT GCCGCTAAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGA AAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTG AAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTC ATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGC GAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACC ATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCC AGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAG AGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTT GGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGC CACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTG TTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTG ATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATT GAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCT TTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTT AGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAA ACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTT AACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCA GGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGT CCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCT TTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTG >In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000355710_chr10_43612032_+_5680nt CGGCGCCCTAGGGCTGCTGCCGAGGTGCTCGCCTGCCCGCCCGCCGGCCTCGGGGGGCCCGGGAGGCGTCCGGCGGGGCGGGGCGGCGCG GCCCGCCACCATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCT CGGGCTGCTCGAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCT CAAGCTGCTCTTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTA CCTGAACGGCGTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAG CAGCAGCTCCCTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGA GAACCTCTCCATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGA CAAGAGGCCCTACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAA CCAGCACACCAACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCA GACTCGGCTGAAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGA CATGAAGCGGCTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGA GATTCTCAACAAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAA AGTCGCCATCCACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCA GCAGAGGGACACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCAC GGCGCAGAACAAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGA GTCGGAGAAATACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGA CAAGCTGCAGACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCT GCGGCAGATCAAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCA GGAGCTGAAGGAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCG TGACAGCATCCGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGA CACCCGCAAGCAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCG ACAGCTGATGGCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGAC GGAGGATATTGACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCAC TAAAGTGGACAAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGA CAAGAAGCAGGCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGT CACGCCGCTGCACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAG CCCTGCCGCTAAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCT TGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGC CGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACA TGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCT CCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCT CACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGC AGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGT GAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTC TTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGAC CGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCC GGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTC CCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATG GATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGG GTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACA TTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTG GCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGAT TTTCCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCA GTGTTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCT GAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCT GGCCCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGA GGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTG GTTTTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAG AGGGCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGT ATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACAC CCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAA CTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGAT GTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAA GATGTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCC TCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATT ACCAAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCAC AAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGG AGAGTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATC TATAGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAA AAATGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGG GGAATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTG GAATTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAA ATCTATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCATG >In-frame_DLG5_ENST00000372388_chr10_79588640_-_RET_ENST00000340058_chr10_43612032_+_4222nt CGGCGCCCTAGGGCTGCTGCCGAGGTGCTCGCCTGCCCGCCCGCCGGCCTCGGGGGGCCCGGGAGGCGTCCGGCGGGGCGGGGCGGCGCG GCCCGCCACCATGGAGCCCCAGCGCCGGGAGCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCT CGGGCTGCTCGAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGAGGCGGGAGGCGCCAAGGCGGAGCTGCTGCT CAAGCTGCTCTTGGCCAAGGAGCGGGACCACTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTA CCTGAACGGCGTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGTCCTGTCCACCATGCCCTCAGACTCAGAAAG CAGCAGCTCCCTCAGCAGTGTGGGCACTACCGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCAGCAAGTGAATGAGAAGGTGGA GAACCTCTCCATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCTGGCCTTTGCTACGCATGGCACGGCCTTTGA CAAGAGGCCCTACCACAGGCTGAATCCTGACTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAA CCAGCACACCAACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCACACACTCCACAGCCGGCTCCTGAGTGACCA GACTCGGCTGAAGGATGACGTGGACATGCTGAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGA CATGAAGCGGCTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCAGCAGGTGTTGAAGCACAACGGGTCATCCGA GATTCTCAACAAACTGTATGACACGGCCATGGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAA AGTCGCCATCCACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCGGTTGCTGAAGCAGACAGAGATGCTGACCCA GCAGAGGGACACGGCCATCCAGCTGCAGCACCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCAC GGCGCAGAACAAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCTGAGAACCACGCAGGTGAAGACAGCAAAGGA GTCGGAGAAATACAGGGAGGAGCGGGACGCTGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGA CAAGCTGCAGACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAAGAAGGCGGCCAATGAGGAGATGGAGGCGCT GCGGCAGATCAAAGACACGGTGACAATGGATGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCA GGAGCTGAAGGAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTTCCAGGAGCGAGACAAGATTGTAGCAGAGCG TGACAGCATCCGGACACTGTGTGACAACCTGAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGA CACCCGCAAGCAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGAATCCCAGTTGGAAAAGGAGGCCCGGTTCCG ACAGCTGATGGCCCACAGCTCCCACGACTCGGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGAC GGAGGATATTGACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTGTTTCCCGGGGGACTGTGGCATATTTGTCAC TAAAGTGGACAAAGGAAGCATTGCTGATGGCCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGA CAAGAAGCAGGCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCGGCGGAGGAAGTCCCTGGGTGGGAAGGTGGT CACGCCGCTGCACATCAACCTCAGTGGACAGAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAG CCCTGCCGCTAAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCT TGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGC CGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACA TGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCT CCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCT CACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGC AGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGT GAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTC TTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGAC CGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCC GGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTC CCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATG GATTGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGA TGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTAC ATTTAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGA AAAAACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTA CTTTAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACA GCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCC CAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACA TCCTTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGT |
Top |
FusionGenePPI for DLG5_RET |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| DLG5 | SORBS3, CTNNB1, CD81, BTBD10, TERF1, DLST, PFN1, UBC, CUL3, BAG5, MARK3, TPM1, BTRC, MED4, CEP104, CEP152, CEP128, CEP135, CEP89, CNTRL, NINL, ODF2, SASS6, RPGRIP1, CDK1, MARK2, FGFR1OP, GAN, CDH1 | RET | STAT3, DOK6, DOK5, SRC, SHC1, PTPRF, DOK2, DOK4, DOK1, GRB2, CRK, PLCG1, PDLIM7, GRB7, FRS2, NRTN, GFRA1, GRB10, IKBKG, MCRS1, CBL, CBLC, RET, HSP90AA1, NOTCH2NL, NOTCH3, AIP, EGFR, NTRK1, ZBTB48, HNRNPD, SORT1, SYNCRIP, SGTB, BAG6, HIST1H3A, KYNU, TXNL4A, ZCCHC8, ICE2, MAPK3, PTK2, MAPK1, PTPRR, DUSP26 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DLG5_RET |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | RET | P07949 | DB05294 | Vandetanib | Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305} | small molecule | approved |
| Tgene | RET | P07949 | DB08896 | Regorafenib | Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305} | small molecule | approved |
| Tgene | RET | P07949 | DB00398 | Sorafenib | Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305} | small molecule | approved|investigational |
| Tgene | RET | P07949 | DB08875 | Cabozantinib | Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305} | small molecule | approved|investigational |
| Tgene | RET | P07949 | DB08901 | Ponatinib | Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305} | small molecule | approved|investigational |
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RelatedDiseases for DLG5_RET |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | RET | C3888239 | HIRSCHSPRUNG DISEASE, SUSCEPTIBILITY TO, 1 | 15 | UNIPROT |
| Tgene | RET | C0025268 | Multiple Endocrine Neoplasia Type 2a | 14 | CTD_human;ORPHANET;UNIPROT |
| Tgene | RET | C1833921 | Familial medullary thyroid carcinoma | 14 | CTD_human;ORPHANET;UNIPROT |
| Tgene | RET | C0025269 | Multiple Endocrine Neoplasia Type 2b | 8 | CTD_human;ORPHANET;UNIPROT |
| Tgene | RET | C1275808 | Congenital central hypoventilation | 4 | CTD_human;ORPHANET;UNIPROT |
| Tgene | RET | C0009404 | Colorectal Neoplasms | 2 | CTD_human |
| Tgene | RET | C0019569 | Hirschsprung Disease | 2 | CTD_human;HPO;ORPHANET |
| Tgene | RET | C0006413 | Burkitt Lymphoma | 1 | CTD_human |
| Tgene | RET | C0027662 | Multiple Endocrine Neoplasia | 1 | CTD_human |
| Tgene | RET | C0031511 | Pheochromocytoma | 1 | CTD_human;HPO;UNIPROT |
| Tgene | RET | C0038220 | Status Epilepticus | 1 | CTD_human |
| Tgene | RET | C0040136 | Thyroid Neoplasm | 1 | CTD_human |
| Tgene | RET | C0206693 | Medullary carcinoma | 1 | CTD_human |
| Tgene | RET | C0238462 | Medullary carcinoma of thyroid | 1 | CTD_human;HPO |
| Tgene | RET | C0740340 | Amyloidosis, Familial | 1 | CTD_human |
| Tgene | RET | C1609433 | Congenital absence of kidneys syndrome | 1 | CTD_human;ORPHANET |
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