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Fusion gene ID: 10040 |
FusionGeneSummary for DISP2_PHGR1 |
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Fusion gene information | Fusion gene name: DISP2_PHGR1 | Fusion gene ID: 10040 | Hgene | Tgene | Gene symbol | DISP2 | PHGR1 | Gene ID | 85455 | 644844 |
Gene name | dispatched RND transporter family member 2 | proline, histidine and glycine rich 1 | |
Synonyms | C15orf36|DISPB|HsT16908|LINC00594 | - | |
Cytomap | 15q15.1 | 15q15.1 | |
Type of gene | protein-coding | protein-coding | |
Description | protein dispatched homolog 2dispatched Blong intergenic non-protein coding RNA 594 | proline, histidine and glycine-rich protein 1proline-histidine-glycin-rich protein 1proline/histidine/glycine-rich 1 | |
Modification date | 20180329 | 20180329 | |
UniProtAcc | A7MBM2 | C9JFL3 | |
Ensembl transtripts involved in fusion gene | ENST00000267889, | ENST00000448599, | |
Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 1 X 1 X 1=1 |
# samples | 2 | 1 | |
** MAII score | log2(2/8*10)=1.32192809488736 | log2(1/1*10)=3.32192809488736 | |
Context | PubMed: DISP2 [Title/Abstract] AND PHGR1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
TCGA | RV | LUSC | TCGA-66-2756-01A | DISP2 | chr15 | 40650641 | + | PHGR1 | chr15 | 40648274 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
Frame-shift | ENST00000267889 | ENST00000448599 | DISP2 | chr15 | 40650641 | + | PHGR1 | chr15 | 40648274 | + |
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FusionProtFeatures for DISP2_PHGR1 |
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Hgene | Tgene |
DISP2 | PHGR1 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for DISP2_PHGR1 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for DISP2_PHGR1 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
DISP2 | PHGR1 |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DISP2_PHGR1 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DISP2_PHGR1 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |