|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 10036 |
FusionGeneSummary for DIS3_KLF12 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DIS3_KLF12 | Fusion gene ID: 10036 | Hgene | Tgene | Gene symbol | DIS3 | KLF12 | Gene ID | 22894 | 11278 |
| Gene name | DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease | Kruppel like factor 12 | |
| Synonyms | 2810028N01Rik|EXOSC11|KIAA1008|RRP44|dis3p | AP-2rep|AP2REP|HSPC122 | |
| Cytomap | 13q21.33 | 13q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | exosome complex exonuclease RRP44DIS3 exosome endoribonuclease and 3'-5' exoribonucleaseDIS3 mitotic control homologexosome component 11mitotic control protein dis3 homologribosomal RNA-processing protein 44 | Krueppel-like factor 12AP-2 repressorAP-2rep transcription factorKLF12 zinc finger transcriptional repressortranscriptional repressor AP-2rep | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9Y2L1 | Q9Y4X4 | |
| Ensembl transtripts involved in fusion gene | ENST00000377767, ENST00000377780, ENST00000545453, ENST00000475871, | ENST00000377669, ENST00000377666, ENST00000472022, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 9 X 10 X 4=360 |
| # samples | 1 | 11 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(11/360*10)=-1.71049338280502 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DIS3 [Title/Abstract] AND KLF12 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | KLF12 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 16615998 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | STAD | TCGA-VQ-A922-01A | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000377767 | ENST00000377669 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| In-frame | ENST00000377767 | ENST00000377666 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| 5CDS-5UTR | ENST00000377767 | ENST00000472022 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| In-frame | ENST00000377780 | ENST00000377669 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| In-frame | ENST00000377780 | ENST00000377666 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| 5CDS-5UTR | ENST00000377780 | ENST00000472022 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| Frame-shift | ENST00000545453 | ENST00000377669 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| Frame-shift | ENST00000545453 | ENST00000377666 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| 5CDS-5UTR | ENST00000545453 | ENST00000472022 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| intron-3CDS | ENST00000475871 | ENST00000377669 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| intron-3CDS | ENST00000475871 | ENST00000377666 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
| intron-5UTR | ENST00000475871 | ENST00000472022 | DIS3 | chr13 | 73345933 | - | KLF12 | chr13 | 74420510 | - |
Top |
FusionProtFeatures for DIS3_KLF12 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DIS3 | KLF12 |
| Confers strong transcriptional repression to the AP-2-alpha gene. Binds to a regulatory element (A32) in the AP-2-alphagene promoter. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DIS3 | chr13:73345933 | chr13:74420510 | ENST00000377767 | - | 11 | 21 | 64_182 | 535 | 959 | Domain | Note=PINc |
| Hgene | DIS3 | chr13:73345933 | chr13:74420510 | ENST00000377780 | - | 11 | 21 | 64_182 | 505 | 929 | Domain | Note=PINc |
| Tgene | >KLF12 | chr13:73345933 | chr13:74420510 | ENST00000377666 | - | 2 | 8 | 317_341 | 41 | 403 | Zinc finger | C2H2-type 1 |
| Tgene | >KLF12 | chr13:73345933 | chr13:74420510 | ENST00000377666 | - | 2 | 8 | 347_371 | 41 | 403 | Zinc finger | C2H2-type 2 |
| Tgene | >KLF12 | chr13:73345933 | chr13:74420510 | ENST00000377666 | - | 2 | 8 | 377_399 | 41 | 403 | Zinc finger | C2H2-type 3 |
| Tgene | >KLF12 | chr13:73345933 | chr13:74420510 | ENST00000377669 | - | 1 | 7 | 317_341 | 41 | 403 | Zinc finger | C2H2-type 1 |
| Tgene | >KLF12 | chr13:73345933 | chr13:74420510 | ENST00000377669 | - | 1 | 7 | 347_371 | 41 | 403 | Zinc finger | C2H2-type 2 |
| Tgene | >KLF12 | chr13:73345933 | chr13:74420510 | ENST00000377669 | - | 1 | 7 | 377_399 | 41 | 403 | Zinc finger | C2H2-type 3 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for DIS3_KLF12 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_DIS3_ENST00000377767_chr13_73345933_-_KLF12_ENST00000377669_chr13_74420510_-_897aa MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIV LQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNE ENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS FLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVH NYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSA SSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQM DPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRI >In-frame_DIS3_ENST00000377767_chr13_73345933_-_KLF12_ENST00000377666_chr13_74420510_-_897aa MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIV LQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNE ENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS FLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVH NYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSA SSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQM DPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRI >In-frame_DIS3_ENST00000377780_chr13_73345933_-_KLF12_ENST00000377669_chr13_74420510_-_867aa MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIVSAWRPGTWASVA SSLRLPGSLETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDR LACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQA STLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQ TQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHP VPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNET GSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKP >In-frame_DIS3_ENST00000377780_chr13_73345933_-_KLF12_ENST00000377666_chr13_74420510_-_867aa MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIVSAWRPGTWASVA SSLRLPGSLETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDR LACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQA STLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQ TQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHP VPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNET GSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_DIS3_ENST00000377767_chr13_73345933_-_KLF12_ENST00000377669_chr13_74420510_-_2691nt ATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAGACGACATCGGC TGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTCTGC CCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGATGTTCTTGAGGACCCTGCCATCAGGAATGTAATTGTG CTACAAACAGTTCTTCAAGAAGTGAGAAATCGCAGTGCCCCCGTATATAAACGCATCCGAGATGTGACTAATAACCAAGAGAAGCATTTC TATACTTTCACTAATGAGCACCATAGAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATAGAGCGATTCGA GTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGAAAC AAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAACTCATAGATCGT CTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAAGGC ATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATGGCGACAATGAA GAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAGAGT CAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAGAACGAATGCTT AAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATGCTT TCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAACCAGACAGGCT TCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAATTTA GGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGGCTGTTCTTAGT TTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGACCCA CCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTGCTGATGTGAGC CATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTCCAAACGTCCAC AACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAGATCACTTCCAA ACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCATGACAGCATCT GCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAGTATCTTCAGCG TCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACATTATCCATCCC GTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGGTGCCTGTTGTC TACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCAAAGCACAAATG GACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCGTTAATGAAACT GGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAATGAATAATCAA AAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAAAACGGCGTATC CACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAGGAGAGAAACCT TACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGGGAGTGAAGCCA >In-frame_DIS3_ENST00000377767_chr13_73345933_-_KLF12_ENST00000377666_chr13_74420510_-_2691nt ATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAGACGACATCGGC TGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTCTGC CCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGATGTTCTTGAGGACCCTGCCATCAGGAATGTAATTGTG CTACAAACAGTTCTTCAAGAAGTGAGAAATCGCAGTGCCCCCGTATATAAACGCATCCGAGATGTGACTAATAACCAAGAGAAGCATTTC TATACTTTCACTAATGAGCACCATAGAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATAGAGCGATTCGA GTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGAAAC AAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAACTCATAGATCGT CTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAAGGC ATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATGGCGACAATGAA GAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAGAGT CAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAGAACGAATGCTT AAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATGCTT TCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAACCAGACAGGCT TCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAATTTA GGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGGCTGTTCTTAGT TTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGACCCA CCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTGCTGATGTGAGC CATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTCCAAACGTCCAC AACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAGATCACTTCCAA ACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCATGACAGCATCT GCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAGTATCTTCAGCG TCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACATTATCCATCCC GTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGGTGCCTGTTGTC TACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCAAAGCACAAATG GACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCGTTAATGAAACT GGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAATGAATAATCAA AAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAAAACGGCGTATC CACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAGGAGAGAAACCT TACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGGGAGTGAAGCCA >In-frame_DIS3_ENST00000377780_chr13_73345933_-_KLF12_ENST00000377669_chr13_74420510_-_2601nt ATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAGACGACATCGGC TGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTCTGC CCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGTAAGTGCCTGGAGGCCGGGGACCTGGGCTTCTGTGGCC TCCAGCCTGCGACTCCCAGGCAGCTTAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATAGAGCGATTCGA GTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGAAAC AAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAACTCATAGATCGT CTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAAGGC ATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATGGCGACAATGAA GAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAGAGT CAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAGAACGAATGCTT AAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATGCTT TCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAACCAGACAGGCT TCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAATTTA GGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGGCTGTTCTTAGT TTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGACCCA CCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTGCTGATGTGAGC CATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTCCAAACGTCCAC AACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAGATCACTTCCAA ACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCATGACAGCATCT GCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAGTATCTTCAGCG TCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACATTATCCATCCC GTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGGTGCCTGTTGTC TACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCAAAGCACAAATG GACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCGTTAATGAAACT GGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAATGAATAATCAA AAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAAAACGGCGTATC CACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAGGAGAGAAACCT TACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGGGAGTGAAGCCA >In-frame_DIS3_ENST00000377780_chr13_73345933_-_KLF12_ENST00000377666_chr13_74420510_-_2601nt ATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAGACGACATCGGC TGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTCTGC CCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGTAAGTGCCTGGAGGCCGGGGACCTGGGCTTCTGTGGCC TCCAGCCTGCGACTCCCAGGCAGCTTAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATAGAGCGATTCGA GTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGAAAC AAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAACTCATAGATCGT CTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAAGGC ATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATGGCGACAATGAA GAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAGAGT CAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAGAACGAATGCTT AAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATGCTT TCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAACCAGACAGGCT TCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAATTTA GGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGGCTGTTCTTAGT TTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGACCCA CCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTGCTGATGTGAGC CATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTCCAAACGTCCAC AACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAGATCACTTCCAA ACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCATGACAGCATCT GCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAGTATCTTCAGCG TCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACATTATCCATCCC GTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGGTGCCTGTTGTC TACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCAAAGCACAAATG GACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCGTTAATGAAACT GGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAATGAATAATCAA AAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAAAACGGCGTATC CACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAGGAGAGAAACCT TACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGGGAGTGAAGCCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_DIS3_ENST00000377767_chr13_73345933_-_KLF12_ENST00000377669_chr13_74420510_-_12193nt GGAATGGAAAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGC GGCGAGGCAAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAG ACGACATCGGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGA GCAGCGTCTGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGATGTTCTTGAGGACCCTGCCATCAGGA ATGTAATTGTGCTACAAACAGTTCTTCAAGAAGTGAGAAATCGCAGTGCCCCCGTATATAAACGCATCCGAGATGTGACTAATAACCAAG AGAAGCATTTCTATACTTTCACTAATGAGCACCATAGAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATA GAGCGATTCGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATG ACAGGAGAAACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAAC TCATAGATCGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGC TACAGCAAGGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATG GCGACAATGAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTC TCCCCAAGAGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAG AACGAATGCTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATT GTGGCATGCTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAA CCAGACAGGCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTG TGAGAAATTTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGG CTGTTCTTAGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTA GTGTAGACCCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTG CTGATGTGAGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTC CAAACGTCCACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAG ATCACTTCCAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCA TGACAGCATCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAG TATCTTCAGCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACA TTATCCATCCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGG TGCCTGTTGTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCA AAGCACAAATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCG TTAATGAAACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAA TGAATAATCAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAA AACGGCGTATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAG GAGAGAAACCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGG GAGTGAAGCCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGT GAGGAATGCTACCTGTCCAGCTGAGCGTAAGAGCTGGATCTCTTAGCGGCACCCAATTCAGCAGGGCTGAATCCCCTTCACAGTGTTAAC ACAAAAGGGCATCACCATCCCACGATGTCTGAAACCAGAGCAGGAAAAAGAAGGCACACTTCTTTTGGTCTGAAGGTAACCCCCATCATG ACTAGACGAGAACCGTCTTTACCCGGGCCTGGGAGCTCAGTGACATAAATGCTGAAGAGACAGGCATTGTTTTCCGTGCTGTGTCCTCTG CCATTTAAAGATGTTTGTAGCTTGTACATTTTCTGAGCTGTCAGACATTTTGTTATTGATACCTTAAAGGTCACCTACCACAAATTGATG GCTAGAGCAAGACCTTTTAAATTTGGATGAATCTCCCATCATCCCATCCCTTAACCCCTTTTTACAGAAATTTTAGTTACAATCTGAGTA AGCTAGAACACACATCCAATCTGTTACCAGCAAGCAGCATGAAAGTAGAAACGAAGAAGCAGATGGAGAGGTCCCATTACCTGCAAAGAA AGGGCACTCAGGCAGCCCTTTGCAATCGCGATGGCAGCCACTAGATATCACTCTCAACTTGTCATTCTGCCATGCCCTGAAGAAAACCAA CATTGAATCTTTCATTTGTTTGTCGTTGATTGTTTTTGTTTTGTTTCGATTCTGTTTTGTTCATCTGTTCGAGCAGAGGGGCAGTTGAAG TCTCGTCCTGGTCTCTGCCCTGGCATGGACTGGCACAGAGGTGTTCTGTAGTTGAATAGGAAGAGCCTGTCTAAAAAACTACTGCCCCAC TTCAAATTGCAGTGTTCTGTCACCTAGGCATCATCTCTTCCTGCCCCTAGTATTTGATTACAAGGAACCAGGGGAAAAAAACTTTCTTAG ACACACTGGCACCAAGGTAAGAGGTGGGGCTGCCCAGGCAAAGTCAGTGAACATGAAAACTCAGACAAAGCAGAGATGGAAATAATGCGC CTCTTGAGGAGAAAAGCAATAATGAATAAAAGGACTTTCCTACAATAACTTCACTGAGGACTCACGTTACCAATTTTCATACTTACTAAA GGGATTGTAAAAAACACCCCAGCATTTTAGGTGTCTTGGTTCCATTTACAGCACTGAGGTAATCTTTCTGCTGTTTGTTGTCCTGCTTGG TTGAGTACCACAATTAAAGATTATGCTCCCCTTTTCTTGTTTGAAAACAGTTATTTGGTGACTAGAAAGGCAAGGGAGGCATAGCCGGGA ATTAACTCTTCGGTTAATGGGTCAGTTCTCCTTGGAACTGAATCAGTGGAAAGAGAATGCTTCCCATAGAAAGCCCGACATGGTGCTAGT TTCCTCTCTTGGAGAGCCAAGGATAAGTGACTCTCCAATAGGTTCTTCTATACCGATTTCATTTTCTAAACTGTATCAGGACCCAGGTGT CCTGCATTGGCATCTGCAGGGATATTGAACCCACTCATCCTGTGCAGAGGATGAGAGGAAGGTGTTAGTTCCATCAGCCCCATAAAATTA TGAACCTTTTTGCAACTAGGAACATATACAGTAAACAAGCAATACATCACCAACGAGCATTCTTTCAGAAAAATTACCATATTTTTGTCC CCACCACAAGCTGGGTTTTTTTCCAGCTTTCTGTGGCTGAGGGGCTGGTGAGATTTTTTGTTGTTATTGTTGTTGTTGCTAGAATTTTTT ATAGCTTAGATATAAAAGGTCTCCAACAAAGACCTTTGCAATATATTTTAATTACAAACACTTGATTTTGGGAATTGCACATATTAACCT CACAATATTACTAGCTCATTTTTAAATGTCTGGACATTCTGAAATAATTTCCGGTTACAGAATTACCCTTTTTAGGATCATCTTCTAATT CAGATAATCTTATTCTGATGAAGCGAGAACTATGAACGTTGAAACAAGGACAATTTGTGTTGGATGGTATTCAAAAGGAATTTTTTAAAA CATTAAGCAACAGTGTAATGATTTTCAGGTCAAATTATGGCTTCACAAATATGTGCTCTATATTGTCTGCCAGGTCTCAAAAATTCATCA AGCAATTTCCCTCCAACAAGGGCTGCAGTTCTAGTGATAAATAGCATCTTTAGCTGCACAGTCTACTACTCATCAACCAGTGGGTTTTTT TTAGCACCTGGAAAGTTTTTTTGTACTATATGCAACTCCTACTTCACATTGCCTGTGACCATTCAGAATAGAAAAAGGTCTGTTGATGCA TGCCAGTGCTGGTTACTAGTCAGTGACAGAGAACACAGAGAGGGACAAACACAGCCATGAACCCCCTGGCACTAGTACCAGCACCTAGTT GGCAAGTAGTGGGTGCATCTCTCAAGTGAAGTGTAGATTTGTATTTAGTCCTGCTTGCTCTCATAAAAAGAGCCAGTTCTTTTCTCTGCT GAAAGATGTCTTGAGAGTATTACAGGTAGACTTGGTTTTTAGAATTCATAAAACTGACAGGCAGGGGAATCTTCCTGAGTGACAGCTTGG TTTAAATTTAGCACAGAACTAGATGAGTTGCACTTTTCTAATAACATAGGATGGATTTGGGGAAGGGAACATTTTCCCTCATCCTCTGAA AGTGGAAACCAGACTGAGATGGTAAGTTAACTGATAAAACCTGTCAGCATTCCATCATTTTCCCCTTTTGACGTATCAGTACTTCTAAGA AGGGATCTAAGCACAATTAAGTGAATTGAGTCCCTGGTCTAGCCTCAGGAACTGAAACTTCTTTGGGGCTTGTCTTGAGACGTGGCAAAT TCTCCTTGGTGAGTTTTCTAAAAGTATTTCCCCATGGAAAGGAGAAAGTGGTTTGGGACAGAAAGAAATGGAATGTCTTCAGTCATGGAA GAGCCTCCATTTCATCTCATGTCCATTTCTAGCCTCTTTCAAAAAGCACAGTGCATCATGAGCAACAGAAAAGCAGTAGAATCCTAAAGG ACATAACAGTTGTTCCGTAACTAGAAGCATTCTTTGATTTTAAATTTGAAGCTGTTCAGTTTGCAGCTGGGGATATGTGCATGGTTGGGA ACTTATACACATAGAGCCATTAACTACTTAAGCAGCTGCAGTAGACCTGATTTTCTGTTTGCAGTATAGAGATTGATTTCAAGGGAGTTA CATTATTTGAAAAGTTATGACTTTCAGCCTTTGAGGTTTTAAGAATCCCTTTTCATGGTCTGATCTTAAGTTGTTTGAAAAAAGATTCAC GCTTCTGCATCCACCTCTGCCCTCATTCTGTCAATTGTGTGTGGACTCTGAGAAGCCTGCTTGATAACTTGTCTTAAGTTCTATTAAGGC AGTTAGACTGAGATTTCTAATGACTTCACCATAAAGATTATACTTCTGCCTGGCGTCGTTTCTATAAAACACTATAGGACATTTGTTTTC AAAAGCAGTTGAGTAACAGCAACATAAACCACATTTTTTAAAAAAATGAGCACTTTTCATTCACTTGAAAGCTTAAGTGGGAAAAAGGAA GATGATTGTCAGGGGAAAAACTTACAAAATGCTACAGTGTTTACAAATGCCAGTTCCAGGTGATTAGAAAGGCCGTTTTCATTATGGTTC AGATTTGGAATAGCTTATGCAAAGATTGTGTTCATTTTTATACAATTCTTTTTAACTTTAAATTGCCATCTGTGTTTTAAACATAATTCT GCACTTTGGAATCAGTTCATTAGAATGATAACATTTATATGGATAAAGATGCAGTATTCCTTATTCTGTACTTGATTTATTATACTTACC AAAGCTGCAACTGAATAAATCTGGTGAGGTGAGGCCTTCAAAATGTATTAATACGCCTTTGTTATGTTGTTATGACTGCTTAGAAATGTA GCCATGATGTTGTTCTAAAGATGTCTTAACATTTATAGTGAGGATTGACAGAAATTAAGCAGTGTTAAGAATACCAGCATCCATGTTACA GTCTGCGTATAAGGGACTGAATGTGAGGTAACTCTTATGAATCATAATAGGCCCAGAAAGCCTTAATATTCATAGTTCATAATCCAGTCT CAGATTTTGCTCTTCAATGTTGCCTGTAAACTTAGCAGGTAAATGTATTCTAGTATAAAACATCATTGACCAAATCTCTTCCTTTAGTTT TTCTGAGGTAGTGCATCCCATTAAAAAAGTCTCTTCAATTAGATTTGGCTTTAGTTTAGAAAGGGGTTTGGTAAGTCATGTCTTCCATAT GACATTTCTACTCATCCCCACACTGCCTTCCACTTAACCTGTACAGACAGCCCCAACACATGCACATGTGTGTACACAACTGTATATGCA GCAGCCAGTGGGCTAACAAATATCAGCAAAGAACTTTTTTAAAAAGAATTTGTAATAATCCGTGCTGTCTAGAAATGTGAGTTACTTACC TTATTAGGAAACCGGCTTATAATACTATATATGACTCTGCCTGCATTTTATAGTTAAGAAATGTACATAAAAATTGCTATATTTTCACAG TTTCATTATAATGTCTGTTTAGTAACCCATGTCCACTGATACTTTAAATATGCTAATTACTGAGCAATTGCAATAGAAATCCAGATTTTC ATAAGAAAATGAAATAGAAGGATACTGCATCTTTAAAAAATAGAGTGAAGATATTTTACTGTATTCGTAACATATGTGATAGTGGAAAAA GTATTTTCAAACTCACAAATTTTACAGAGGTTGTAAATAGTTTGATGAAGTATGTTGGGAAAGAGAGCTTCTAGTTTTCATCACAATAAA AAGAAAAAACTTGTTCAGATATGCCTTGTATATCTTACACACAATGAGTGAAATTGCCATGGGAACTCTGTCCAACTTTGTCAGAGCATG CTCTTCGTGTTCTGTTCAAAATAGAGTGGCCACTTGTCATGGTTTAGCCAGGATGGTTTAAAATATAATGAAGTCATTTTAAGTTGCAGA CAACTGATTCCAAACTAGTAATGTCTTTTCCTGAAAAGGGCAAAACAGCTGCACAGGATTTTGCTTGTACTAAAGAGGAGCATCTTACAA TTGTTCTCTTTTCTCAGTTATCTCCCTCCTCAACAGAGTGTGAACAACCATACAGGTGTTTATTCTTGTTTTATTCCAGGGAGACTGCTT TTAGGTATAACTACATGTTGACAAGATTAAGTGCTGTGGATATGGCCACGTGTTAAAGGAATCTATACTCGCAATAGGAATAAGCTAATG CCCATTTTCAGAAATAAATTAAATGCTGAAAGTGCCTGTCAGTAAACCTTATGACCAATGAGATATTCCTATACTTTTACACAGCAATAA TTCTTAATAAGACTGGGTTTTTTCCTGCACATGTGAACACACACACACATACACACAGAGAGAGTAAATACATACACATAGTAAATCAAA TCTGTTCACATGCCCACAAAAAACGCTTTTATAGCTTTCAAATATACCTAATCTTGTTTACATTAACATTTCTTAATTTGATCTTTCTAA CTTGCAGAACGTTAAGAACACAAATCTGAACATTAAGTTTATCTTCAGTGAACACTATTGCATATGGTAATTATAATTTCCAGATAAAAA GTTGACTGTCATTTGCCCCAAACTTATGAAACAGTATGTATGATTCAAAAAGTTTTGCTCAGTTAAAAACACCAATTTATTTGGCGCAAA AGACTGAAGGATATTTGTTTGCTTGTTCATTTTATCCACTCATATCAAACGCACAAATTCATCTTTACATTTCTTCATTCCCCTTTCCCC TAATATTTCCTATTATCATCTTAAGAATCATTTTGGAATGAATATTGACAGAATCATTTCTCCCCAAAAAGTCTGTTGAAGTACCACTGA CACTTAGTAAGCCTAGCCTTTAACCATCTTTGCAGTTAGTCCTAAAAATTACCAGATGCACATTCAGAAGCTCACAGGTTTTTTCCTGTA ATTACTGTACTGCTAAAAGTGGAGTCATGGATAGAAATATACAATGAGACTATATGAATAGACATGAACCCTGGAAATTCTCCAACCCTG CCATCTCAGAGCACAAATTCACCCAAACAAGCTACTGAGGCTATCAGTAAAATTATACTCATGGAGAGTCACACATCGGGTAAGGGCAAT TTTAAAAGTAGGACTGTGATTAAACATTCAGGCTTTAGACTTCCATGATGGACTCAGACCACAGGCCTCAAAAAAACATCCACTGTTTTC TCCTCCCAATGTTAGAAAGAAGAAAAGGGAGACGGAAATGTACCAGGATAAGGGGGTAAAATAACCAATTAAGTGTCAAAGGAAAGCTGC TGGGTTCCTTAATCTCACTGAAGTCAAGTCTTCTGACTGGGCTTCTTACCATGTGTTGTCTGAAAAAACTAAAGTACCTTGAAAGGTTAC ACATTCAGCAAACCATGAAGATAATAGCTATTCTTTATTAAACACTGTGTGCCAAGCAATAGACTAGGCAATTTTTAGATACGTTACCTG CAACCTGTACAACATTTCTACACTTTATGGATGGGAAACGGAGACATGGGAAGTGTGGCTGAGTTGTTCATGGATGTAGAAATAGTAAAC GGCAGAGTAGGAAAGTGAAACCGCCTATCTCTGACCTGGAGGTCTGCCTGTATCTTTCCCACTCCACCACACTGCACGTGGGTGTCCCGA AACCACCTTCCCAGATTCCTGACTCTCAGTAATTTTATTATGGACAACATGCATGAGTAGTCATCATATTTTTCAAGTGAAATATCGGGA CATGATATAACACATGACTTAACAATGGTACTGAATATTTGAAATCAGGCCTTTCCCGGAAAATCATGCATGAAGGATCATTATAAACAA ACAATAGCAACCAGTTGTCTCCCCGAACTTGTCACTTTTCTCATAAATGTCTGGCCTGGAGCTCCAAAATCATCCAAATACTTAGTAGCA TTTTAGCCTGAGTACACTTTCTCAGTTCCTCAACTCTTTGTATACCTTTCCACCAATATAGACATTCTAGAATCTGCTTCAGATGCATTT GAAATTTTCACCCCCATGGAACTAGTGATTAATATCAGAGCCCACTCTTGCAGTTGGTAATGGGGTGGCAATCAAACGTTCAGATGATGA TAAAGGAGAGATAATGGATAATTCTTTTTCAGAGTTCTCACTTAACAGCTCTGTTGTGGAATGTTTTAAATAGTCTTATAAATAATTTGT TTATAGTATTGTTGTTAGTTTAATTGAATTTTATGTAAGAAGCTGTCCAACATCAGAGAAATGAAATTCCTCCCACTTTCTGTGTAGAAC AAGGTCTCTGACAGTATTGATTCATGGAAGTACTAATGGACTTAGAAAACATTAAGAGAATGTCATTTCTCATAGTGTTTCTGTTTCTGA AAATGAATCTCCTGAATTATTATCTTTCTCCCTGTTACTTGGCTGGGGAAAGAGATAGAAGCTGTATAAACAAATTCTCTTCCATGCTCA AAGCAAGTGTTCCATGTGCACAACCTGCTGCAGACTGGGGCCCTTCTCAGTTAATTGGGTTTCACAAGCAATAATTTCTCCACAACAAAA ACCACAACTTGAAGTGAGTTGAAAAGAGATCAATAGTGGAAACAGTCGCCTCAGTACTTTTTCTTTCTGGATTTCATCTCTAGAAATTTG AAGTGTTTGAGACAGAGTCCACCCTTTGTGCAAGGCGAGAACCAATGAATGGACTCCTTGTGTGAATTATTGCATCTTCTTCCAAAGCAG GTTCATCAAGACTTTCACAGAGATTCATTTTTGTTGAGAAGTAAGGGTTAATAGGAGGATAGAATTTGGATCCAAATCTAGTGATAAAAG TGTCCAAGCAATCAAAAAGTAAGATATTTTAGGGACATACCAACATCTTCCCTTTCTGCTAATTTCATGCTCCAAAGATATGGCAAAAAA AAAAATCATAAAAAGTGCTTTTGCCCTACTTGTGTTCTAGTTTTCCCATGGCAGAATTTTGTAATTACATCCAGAATATAGTGTATATTT TGTTCCTCAAACTTTATTACATTGGATGGATATTGTTGAACTGGGGCACTGGTGCCTATATTCAAGGCTCTTTCCTATCAACGTGTCTGT CCACGATTTGTTGTGTTTAAAGCTTCATTTTGAAAAATCACTGTCCCCCTGTGGGGTAGTGACTGTATTGTTTTGTTCATGTCTATGTGG GACACATTGCATCACATGGCAAACCAACTCTCTGTGGATGTGAGATAAGTACTTATAAAACCAGCTTGAAAACATCGTCTTATGTATTAT GTCATCCTGCATCATAATGCAATTATGTGTATCATAACATGCTCATTTAAAAAAAGAGAAACCAGCAAATTCATGTTTGTCCATAGAAGA ATGTACTCAGAACTTTGTGTTGTGAAACGATGAGAACAGACCACCTTTAAGATACCCACCTGCCACTTAAAATGACTTAGTTATAATTAG TAGTAGTCTAGACGTTGTTCTTGGTGTGTGGGGGTCAATTCTAACGTCATGTTCTTTTGAATAAATCTCTCAGTCATATTTGAAAAAAAA ATACATGGGAATAAAGAAAAATATCATCTTTGGCCAAATCAAGCAGGCATCTTTTTTCTTTTCCTTGACGTTTAGCTCATTATACGTGGT GATTGGATCACGAGATCTGTCCGTGTGAAAATACAGAAACATCCTTTAGTTTACAAAACAGTTATTCTAGGCTTGAAGCCTCTGAACAGC AAATTGAATAGATGGGCTGCATCTGATTTGCTTTATGGATGTAATTTTACAAAACACTCTTGGGTCTCTGACCCCAGGGAGTTAAGAGTG CCCAGAGGAGGTCCTACACATTAAAGGATAAAGCCCCCCAGTGATGCTGGCAAGCAAATGTGTTGAGTTCTTAAATCTTCATTTGGTTTT CTGTTCAGGATTTTAATTGCAAATGAATTTATTTCTCCAGTTTATCTAAAGACCTAATTTCCCAATAGTTTCCTCTGCATTTATATACTC TGTAGTGTTTAGGCAACCCTGTTATAAGTTTATTAATATTATGTAAGTGTTGTTCTTGTATTTATGTATAGTGTATGTATTGTAAATATA CTCAGAGCTTTTTTCCTTTTACTGTAAAATGGTGATTTTTTTGCCCTATGATAATGTAAAGGGAGACCCTCCTAATGAGATTCTCTCAGA GGATGATTATTCCAGTCTATTCTCAGAGATTTAAATGAACAAGTGTTATTGTTTTTAATGGTGTCTCAGACATATTCTGTTGGTGCATTG CTTTTCTGTATTCAACTTTCCTATGAATTGAGCTGTGAACTGAAATAGAGTTTAAACCTTTAACTGTATGCATTTGTATAATTATCTGAA >In-frame_DIS3_ENST00000377767_chr13_73345933_-_KLF12_ENST00000377666_chr13_74420510_-_2883nt GGAATGGAAAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGC GGCGAGGCAAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAG ACGACATCGGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGA GCAGCGTCTGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGATGTTCTTGAGGACCCTGCCATCAGGA ATGTAATTGTGCTACAAACAGTTCTTCAAGAAGTGAGAAATCGCAGTGCCCCCGTATATAAACGCATCCGAGATGTGACTAATAACCAAG AGAAGCATTTCTATACTTTCACTAATGAGCACCATAGAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATA GAGCGATTCGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATG ACAGGAGAAACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAAC TCATAGATCGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGC TACAGCAAGGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATG GCGACAATGAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTC TCCCCAAGAGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAG AACGAATGCTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATT GTGGCATGCTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAA CCAGACAGGCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTG TGAGAAATTTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGG CTGTTCTTAGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTA GTGTAGACCCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTG CTGATGTGAGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTC CAAACGTCCACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAG ATCACTTCCAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCA TGACAGCATCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAG TATCTTCAGCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACA TTATCCATCCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGG TGCCTGTTGTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCA AAGCACAAATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCG TTAATGAAACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAA TGAATAATCAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAA AACGGCGTATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAG GAGAGAAACCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGG GAGTGAAGCCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGT GAGGAATGCTACCTGTCCAGCTGAGCGTAAGAGCTGGATCTCTTAGCGGCACCCAATTCAGCAGGGCTGAATCCCCTTCACAGTGTTAAC >In-frame_DIS3_ENST00000377780_chr13_73345933_-_KLF12_ENST00000377669_chr13_74420510_-_12095nt AAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGCGGCGAGGC AAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAGACGACATC GGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTC TGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGTAAGTGCCTGGAGGCCGGGGACCTGGGCTTCTGTG GCCTCCAGCCTGCGACTCCCAGGCAGCTTAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATAGAGCGATT CGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGA AACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAACTCATAGAT CGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAA GGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATGGCGACAAT GAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAG AGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAGAACGAATG CTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATG CTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAACCAGACAG GCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAAT TTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGGCTGTTCTT AGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGAC CCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTGCTGATGTG AGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTCCAAACGTC CACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAGATCACTTC CAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCATGACAGCA TCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAGTATCTTCA GCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACATTATCCAT CCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGGTGCCTGTT GTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCAAAGCACAA ATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCGTTAATGAA ACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAATGAATAAT CAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAAAACGGCGT ATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAGGAGAGAAA CCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGGGAGTGAAG CCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGTGAGGAATG CTACCTGTCCAGCTGAGCGTAAGAGCTGGATCTCTTAGCGGCACCCAATTCAGCAGGGCTGAATCCCCTTCACAGTGTTAACACAAAAGG GCATCACCATCCCACGATGTCTGAAACCAGAGCAGGAAAAAGAAGGCACACTTCTTTTGGTCTGAAGGTAACCCCCATCATGACTAGACG AGAACCGTCTTTACCCGGGCCTGGGAGCTCAGTGACATAAATGCTGAAGAGACAGGCATTGTTTTCCGTGCTGTGTCCTCTGCCATTTAA AGATGTTTGTAGCTTGTACATTTTCTGAGCTGTCAGACATTTTGTTATTGATACCTTAAAGGTCACCTACCACAAATTGATGGCTAGAGC AAGACCTTTTAAATTTGGATGAATCTCCCATCATCCCATCCCTTAACCCCTTTTTACAGAAATTTTAGTTACAATCTGAGTAAGCTAGAA CACACATCCAATCTGTTACCAGCAAGCAGCATGAAAGTAGAAACGAAGAAGCAGATGGAGAGGTCCCATTACCTGCAAAGAAAGGGCACT CAGGCAGCCCTTTGCAATCGCGATGGCAGCCACTAGATATCACTCTCAACTTGTCATTCTGCCATGCCCTGAAGAAAACCAACATTGAAT CTTTCATTTGTTTGTCGTTGATTGTTTTTGTTTTGTTTCGATTCTGTTTTGTTCATCTGTTCGAGCAGAGGGGCAGTTGAAGTCTCGTCC TGGTCTCTGCCCTGGCATGGACTGGCACAGAGGTGTTCTGTAGTTGAATAGGAAGAGCCTGTCTAAAAAACTACTGCCCCACTTCAAATT GCAGTGTTCTGTCACCTAGGCATCATCTCTTCCTGCCCCTAGTATTTGATTACAAGGAACCAGGGGAAAAAAACTTTCTTAGACACACTG GCACCAAGGTAAGAGGTGGGGCTGCCCAGGCAAAGTCAGTGAACATGAAAACTCAGACAAAGCAGAGATGGAAATAATGCGCCTCTTGAG GAGAAAAGCAATAATGAATAAAAGGACTTTCCTACAATAACTTCACTGAGGACTCACGTTACCAATTTTCATACTTACTAAAGGGATTGT AAAAAACACCCCAGCATTTTAGGTGTCTTGGTTCCATTTACAGCACTGAGGTAATCTTTCTGCTGTTTGTTGTCCTGCTTGGTTGAGTAC CACAATTAAAGATTATGCTCCCCTTTTCTTGTTTGAAAACAGTTATTTGGTGACTAGAAAGGCAAGGGAGGCATAGCCGGGAATTAACTC TTCGGTTAATGGGTCAGTTCTCCTTGGAACTGAATCAGTGGAAAGAGAATGCTTCCCATAGAAAGCCCGACATGGTGCTAGTTTCCTCTC TTGGAGAGCCAAGGATAAGTGACTCTCCAATAGGTTCTTCTATACCGATTTCATTTTCTAAACTGTATCAGGACCCAGGTGTCCTGCATT GGCATCTGCAGGGATATTGAACCCACTCATCCTGTGCAGAGGATGAGAGGAAGGTGTTAGTTCCATCAGCCCCATAAAATTATGAACCTT TTTGCAACTAGGAACATATACAGTAAACAAGCAATACATCACCAACGAGCATTCTTTCAGAAAAATTACCATATTTTTGTCCCCACCACA AGCTGGGTTTTTTTCCAGCTTTCTGTGGCTGAGGGGCTGGTGAGATTTTTTGTTGTTATTGTTGTTGTTGCTAGAATTTTTTATAGCTTA GATATAAAAGGTCTCCAACAAAGACCTTTGCAATATATTTTAATTACAAACACTTGATTTTGGGAATTGCACATATTAACCTCACAATAT TACTAGCTCATTTTTAAATGTCTGGACATTCTGAAATAATTTCCGGTTACAGAATTACCCTTTTTAGGATCATCTTCTAATTCAGATAAT CTTATTCTGATGAAGCGAGAACTATGAACGTTGAAACAAGGACAATTTGTGTTGGATGGTATTCAAAAGGAATTTTTTAAAACATTAAGC AACAGTGTAATGATTTTCAGGTCAAATTATGGCTTCACAAATATGTGCTCTATATTGTCTGCCAGGTCTCAAAAATTCATCAAGCAATTT CCCTCCAACAAGGGCTGCAGTTCTAGTGATAAATAGCATCTTTAGCTGCACAGTCTACTACTCATCAACCAGTGGGTTTTTTTTAGCACC TGGAAAGTTTTTTTGTACTATATGCAACTCCTACTTCACATTGCCTGTGACCATTCAGAATAGAAAAAGGTCTGTTGATGCATGCCAGTG CTGGTTACTAGTCAGTGACAGAGAACACAGAGAGGGACAAACACAGCCATGAACCCCCTGGCACTAGTACCAGCACCTAGTTGGCAAGTA GTGGGTGCATCTCTCAAGTGAAGTGTAGATTTGTATTTAGTCCTGCTTGCTCTCATAAAAAGAGCCAGTTCTTTTCTCTGCTGAAAGATG TCTTGAGAGTATTACAGGTAGACTTGGTTTTTAGAATTCATAAAACTGACAGGCAGGGGAATCTTCCTGAGTGACAGCTTGGTTTAAATT TAGCACAGAACTAGATGAGTTGCACTTTTCTAATAACATAGGATGGATTTGGGGAAGGGAACATTTTCCCTCATCCTCTGAAAGTGGAAA CCAGACTGAGATGGTAAGTTAACTGATAAAACCTGTCAGCATTCCATCATTTTCCCCTTTTGACGTATCAGTACTTCTAAGAAGGGATCT AAGCACAATTAAGTGAATTGAGTCCCTGGTCTAGCCTCAGGAACTGAAACTTCTTTGGGGCTTGTCTTGAGACGTGGCAAATTCTCCTTG GTGAGTTTTCTAAAAGTATTTCCCCATGGAAAGGAGAAAGTGGTTTGGGACAGAAAGAAATGGAATGTCTTCAGTCATGGAAGAGCCTCC ATTTCATCTCATGTCCATTTCTAGCCTCTTTCAAAAAGCACAGTGCATCATGAGCAACAGAAAAGCAGTAGAATCCTAAAGGACATAACA GTTGTTCCGTAACTAGAAGCATTCTTTGATTTTAAATTTGAAGCTGTTCAGTTTGCAGCTGGGGATATGTGCATGGTTGGGAACTTATAC ACATAGAGCCATTAACTACTTAAGCAGCTGCAGTAGACCTGATTTTCTGTTTGCAGTATAGAGATTGATTTCAAGGGAGTTACATTATTT GAAAAGTTATGACTTTCAGCCTTTGAGGTTTTAAGAATCCCTTTTCATGGTCTGATCTTAAGTTGTTTGAAAAAAGATTCACGCTTCTGC ATCCACCTCTGCCCTCATTCTGTCAATTGTGTGTGGACTCTGAGAAGCCTGCTTGATAACTTGTCTTAAGTTCTATTAAGGCAGTTAGAC TGAGATTTCTAATGACTTCACCATAAAGATTATACTTCTGCCTGGCGTCGTTTCTATAAAACACTATAGGACATTTGTTTTCAAAAGCAG TTGAGTAACAGCAACATAAACCACATTTTTTAAAAAAATGAGCACTTTTCATTCACTTGAAAGCTTAAGTGGGAAAAAGGAAGATGATTG TCAGGGGAAAAACTTACAAAATGCTACAGTGTTTACAAATGCCAGTTCCAGGTGATTAGAAAGGCCGTTTTCATTATGGTTCAGATTTGG AATAGCTTATGCAAAGATTGTGTTCATTTTTATACAATTCTTTTTAACTTTAAATTGCCATCTGTGTTTTAAACATAATTCTGCACTTTG GAATCAGTTCATTAGAATGATAACATTTATATGGATAAAGATGCAGTATTCCTTATTCTGTACTTGATTTATTATACTTACCAAAGCTGC AACTGAATAAATCTGGTGAGGTGAGGCCTTCAAAATGTATTAATACGCCTTTGTTATGTTGTTATGACTGCTTAGAAATGTAGCCATGAT GTTGTTCTAAAGATGTCTTAACATTTATAGTGAGGATTGACAGAAATTAAGCAGTGTTAAGAATACCAGCATCCATGTTACAGTCTGCGT ATAAGGGACTGAATGTGAGGTAACTCTTATGAATCATAATAGGCCCAGAAAGCCTTAATATTCATAGTTCATAATCCAGTCTCAGATTTT GCTCTTCAATGTTGCCTGTAAACTTAGCAGGTAAATGTATTCTAGTATAAAACATCATTGACCAAATCTCTTCCTTTAGTTTTTCTGAGG TAGTGCATCCCATTAAAAAAGTCTCTTCAATTAGATTTGGCTTTAGTTTAGAAAGGGGTTTGGTAAGTCATGTCTTCCATATGACATTTC TACTCATCCCCACACTGCCTTCCACTTAACCTGTACAGACAGCCCCAACACATGCACATGTGTGTACACAACTGTATATGCAGCAGCCAG TGGGCTAACAAATATCAGCAAAGAACTTTTTTAAAAAGAATTTGTAATAATCCGTGCTGTCTAGAAATGTGAGTTACTTACCTTATTAGG AAACCGGCTTATAATACTATATATGACTCTGCCTGCATTTTATAGTTAAGAAATGTACATAAAAATTGCTATATTTTCACAGTTTCATTA TAATGTCTGTTTAGTAACCCATGTCCACTGATACTTTAAATATGCTAATTACTGAGCAATTGCAATAGAAATCCAGATTTTCATAAGAAA ATGAAATAGAAGGATACTGCATCTTTAAAAAATAGAGTGAAGATATTTTACTGTATTCGTAACATATGTGATAGTGGAAAAAGTATTTTC AAACTCACAAATTTTACAGAGGTTGTAAATAGTTTGATGAAGTATGTTGGGAAAGAGAGCTTCTAGTTTTCATCACAATAAAAAGAAAAA ACTTGTTCAGATATGCCTTGTATATCTTACACACAATGAGTGAAATTGCCATGGGAACTCTGTCCAACTTTGTCAGAGCATGCTCTTCGT GTTCTGTTCAAAATAGAGTGGCCACTTGTCATGGTTTAGCCAGGATGGTTTAAAATATAATGAAGTCATTTTAAGTTGCAGACAACTGAT TCCAAACTAGTAATGTCTTTTCCTGAAAAGGGCAAAACAGCTGCACAGGATTTTGCTTGTACTAAAGAGGAGCATCTTACAATTGTTCTC TTTTCTCAGTTATCTCCCTCCTCAACAGAGTGTGAACAACCATACAGGTGTTTATTCTTGTTTTATTCCAGGGAGACTGCTTTTAGGTAT AACTACATGTTGACAAGATTAAGTGCTGTGGATATGGCCACGTGTTAAAGGAATCTATACTCGCAATAGGAATAAGCTAATGCCCATTTT CAGAAATAAATTAAATGCTGAAAGTGCCTGTCAGTAAACCTTATGACCAATGAGATATTCCTATACTTTTACACAGCAATAATTCTTAAT AAGACTGGGTTTTTTCCTGCACATGTGAACACACACACACATACACACAGAGAGAGTAAATACATACACATAGTAAATCAAATCTGTTCA CATGCCCACAAAAAACGCTTTTATAGCTTTCAAATATACCTAATCTTGTTTACATTAACATTTCTTAATTTGATCTTTCTAACTTGCAGA ACGTTAAGAACACAAATCTGAACATTAAGTTTATCTTCAGTGAACACTATTGCATATGGTAATTATAATTTCCAGATAAAAAGTTGACTG TCATTTGCCCCAAACTTATGAAACAGTATGTATGATTCAAAAAGTTTTGCTCAGTTAAAAACACCAATTTATTTGGCGCAAAAGACTGAA GGATATTTGTTTGCTTGTTCATTTTATCCACTCATATCAAACGCACAAATTCATCTTTACATTTCTTCATTCCCCTTTCCCCTAATATTT CCTATTATCATCTTAAGAATCATTTTGGAATGAATATTGACAGAATCATTTCTCCCCAAAAAGTCTGTTGAAGTACCACTGACACTTAGT AAGCCTAGCCTTTAACCATCTTTGCAGTTAGTCCTAAAAATTACCAGATGCACATTCAGAAGCTCACAGGTTTTTTCCTGTAATTACTGT ACTGCTAAAAGTGGAGTCATGGATAGAAATATACAATGAGACTATATGAATAGACATGAACCCTGGAAATTCTCCAACCCTGCCATCTCA GAGCACAAATTCACCCAAACAAGCTACTGAGGCTATCAGTAAAATTATACTCATGGAGAGTCACACATCGGGTAAGGGCAATTTTAAAAG TAGGACTGTGATTAAACATTCAGGCTTTAGACTTCCATGATGGACTCAGACCACAGGCCTCAAAAAAACATCCACTGTTTTCTCCTCCCA ATGTTAGAAAGAAGAAAAGGGAGACGGAAATGTACCAGGATAAGGGGGTAAAATAACCAATTAAGTGTCAAAGGAAAGCTGCTGGGTTCC TTAATCTCACTGAAGTCAAGTCTTCTGACTGGGCTTCTTACCATGTGTTGTCTGAAAAAACTAAAGTACCTTGAAAGGTTACACATTCAG CAAACCATGAAGATAATAGCTATTCTTTATTAAACACTGTGTGCCAAGCAATAGACTAGGCAATTTTTAGATACGTTACCTGCAACCTGT ACAACATTTCTACACTTTATGGATGGGAAACGGAGACATGGGAAGTGTGGCTGAGTTGTTCATGGATGTAGAAATAGTAAACGGCAGAGT AGGAAAGTGAAACCGCCTATCTCTGACCTGGAGGTCTGCCTGTATCTTTCCCACTCCACCACACTGCACGTGGGTGTCCCGAAACCACCT TCCCAGATTCCTGACTCTCAGTAATTTTATTATGGACAACATGCATGAGTAGTCATCATATTTTTCAAGTGAAATATCGGGACATGATAT AACACATGACTTAACAATGGTACTGAATATTTGAAATCAGGCCTTTCCCGGAAAATCATGCATGAAGGATCATTATAAACAAACAATAGC AACCAGTTGTCTCCCCGAACTTGTCACTTTTCTCATAAATGTCTGGCCTGGAGCTCCAAAATCATCCAAATACTTAGTAGCATTTTAGCC TGAGTACACTTTCTCAGTTCCTCAACTCTTTGTATACCTTTCCACCAATATAGACATTCTAGAATCTGCTTCAGATGCATTTGAAATTTT CACCCCCATGGAACTAGTGATTAATATCAGAGCCCACTCTTGCAGTTGGTAATGGGGTGGCAATCAAACGTTCAGATGATGATAAAGGAG AGATAATGGATAATTCTTTTTCAGAGTTCTCACTTAACAGCTCTGTTGTGGAATGTTTTAAATAGTCTTATAAATAATTTGTTTATAGTA TTGTTGTTAGTTTAATTGAATTTTATGTAAGAAGCTGTCCAACATCAGAGAAATGAAATTCCTCCCACTTTCTGTGTAGAACAAGGTCTC TGACAGTATTGATTCATGGAAGTACTAATGGACTTAGAAAACATTAAGAGAATGTCATTTCTCATAGTGTTTCTGTTTCTGAAAATGAAT CTCCTGAATTATTATCTTTCTCCCTGTTACTTGGCTGGGGAAAGAGATAGAAGCTGTATAAACAAATTCTCTTCCATGCTCAAAGCAAGT GTTCCATGTGCACAACCTGCTGCAGACTGGGGCCCTTCTCAGTTAATTGGGTTTCACAAGCAATAATTTCTCCACAACAAAAACCACAAC TTGAAGTGAGTTGAAAAGAGATCAATAGTGGAAACAGTCGCCTCAGTACTTTTTCTTTCTGGATTTCATCTCTAGAAATTTGAAGTGTTT GAGACAGAGTCCACCCTTTGTGCAAGGCGAGAACCAATGAATGGACTCCTTGTGTGAATTATTGCATCTTCTTCCAAAGCAGGTTCATCA AGACTTTCACAGAGATTCATTTTTGTTGAGAAGTAAGGGTTAATAGGAGGATAGAATTTGGATCCAAATCTAGTGATAAAAGTGTCCAAG CAATCAAAAAGTAAGATATTTTAGGGACATACCAACATCTTCCCTTTCTGCTAATTTCATGCTCCAAAGATATGGCAAAAAAAAAAATCA TAAAAAGTGCTTTTGCCCTACTTGTGTTCTAGTTTTCCCATGGCAGAATTTTGTAATTACATCCAGAATATAGTGTATATTTTGTTCCTC AAACTTTATTACATTGGATGGATATTGTTGAACTGGGGCACTGGTGCCTATATTCAAGGCTCTTTCCTATCAACGTGTCTGTCCACGATT TGTTGTGTTTAAAGCTTCATTTTGAAAAATCACTGTCCCCCTGTGGGGTAGTGACTGTATTGTTTTGTTCATGTCTATGTGGGACACATT GCATCACATGGCAAACCAACTCTCTGTGGATGTGAGATAAGTACTTATAAAACCAGCTTGAAAACATCGTCTTATGTATTATGTCATCCT GCATCATAATGCAATTATGTGTATCATAACATGCTCATTTAAAAAAAGAGAAACCAGCAAATTCATGTTTGTCCATAGAAGAATGTACTC AGAACTTTGTGTTGTGAAACGATGAGAACAGACCACCTTTAAGATACCCACCTGCCACTTAAAATGACTTAGTTATAATTAGTAGTAGTC TAGACGTTGTTCTTGGTGTGTGGGGGTCAATTCTAACGTCATGTTCTTTTGAATAAATCTCTCAGTCATATTTGAAAAAAAAATACATGG GAATAAAGAAAAATATCATCTTTGGCCAAATCAAGCAGGCATCTTTTTTCTTTTCCTTGACGTTTAGCTCATTATACGTGGTGATTGGAT CACGAGATCTGTCCGTGTGAAAATACAGAAACATCCTTTAGTTTACAAAACAGTTATTCTAGGCTTGAAGCCTCTGAACAGCAAATTGAA TAGATGGGCTGCATCTGATTTGCTTTATGGATGTAATTTTACAAAACACTCTTGGGTCTCTGACCCCAGGGAGTTAAGAGTGCCCAGAGG AGGTCCTACACATTAAAGGATAAAGCCCCCCAGTGATGCTGGCAAGCAAATGTGTTGAGTTCTTAAATCTTCATTTGGTTTTCTGTTCAG GATTTTAATTGCAAATGAATTTATTTCTCCAGTTTATCTAAAGACCTAATTTCCCAATAGTTTCCTCTGCATTTATATACTCTGTAGTGT TTAGGCAACCCTGTTATAAGTTTATTAATATTATGTAAGTGTTGTTCTTGTATTTATGTATAGTGTATGTATTGTAAATATACTCAGAGC TTTTTTCCTTTTACTGTAAAATGGTGATTTTTTTGCCCTATGATAATGTAAAGGGAGACCCTCCTAATGAGATTCTCTCAGAGGATGATT ATTCCAGTCTATTCTCAGAGATTTAAATGAACAAGTGTTATTGTTTTTAATGGTGTCTCAGACATATTCTGTTGGTGCATTGCTTTTCTG TATTCAACTTTCCTATGAATTGAGCTGTGAACTGAAATAGAGTTTAAACCTTTAACTGTATGCATTTGTATAATTATCTGAATGAAGGCA >In-frame_DIS3_ENST00000377780_chr13_73345933_-_KLF12_ENST00000377666_chr13_74420510_-_2785nt AAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGCGGCGAGGC AAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAGACGACATC GGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTC TGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGTAAGTGCCTGGAGGCCGGGGACCTGGGCTTCTGTG GCCTCCAGCCTGCGACTCCCAGGCAGCTTAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATAGAGCGATT CGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGA AACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAACTCATAGAT CGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAA GGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATGGCGACAAT GAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAG AGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAGAACGAATG CTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATG CTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAACCAGACAG GCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAAT TTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGGCTGTTCTT AGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGAC CCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTGCTGATGTG AGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTCCAAACGTC CACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAGATCACTTC CAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCATGACAGCA TCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAGTATCTTCA GCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACATTATCCAT CCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGGTGCCTGTT GTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCAAAGCACAA ATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCGTTAATGAA ACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAATGAATAAT CAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAAAACGGCGT ATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAGGAGAGAAA CCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGGGAGTGAAG CCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGTGAGGAATG |
Top |
FusionGenePPI for DIS3_KLF12 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| DIS3 | ZBTB17, BABAM1, SIRT7, CUL3, CUL5, EXOSC7, EXOSC4, EXOSC9, EXOSC5, EXOSC8, EXOSC1, EXOSC2, SKIV2L2, EXOSC10, EXOSC3, PPP5C, SH3PXD2B, WDR1, STXBP3, AICDA, NTMT1, TWF1, EGFR, GAS2L1, DCX, NELFE, SSBP3, RBM23, CYP1A1, NMD3, RCC1, GNAS, KPNB1, RAN, RAVER1, SEPHS1, NTRK1, SORT1, RNF126, IQCF1, C1D, MUS81, SERPINB2, SNRNP27, DLX4, FGB, GTF2E2, ZNF212, CCDC94, EID3, SUB1, SARNP, SEPT7, COPZ1, SCYL2, CDK5, SH3GLB1, CHORDC1, PRCC, DRG1, SEPT11, TES | KLF12 | EHMT2, APP, CTBP1, THAP1, DYNLT1, DNMT3L, IDO2, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for DIS3_KLF12 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for DIS3_KLF12 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | KLF12 | C0036341 | Schizophrenia | 1 | CTD_human |
| Tgene | KLF12 | C0236969 | Substance-Related Disorders | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|