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Fusion gene ID: 9836 |
FusionGeneSummary for DGKG_TECPR2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DGKG_TECPR2 | Fusion gene ID: 9836 | Hgene | Tgene | Gene symbol | DGKG | TECPR2 | Gene ID | 1608 | 9895 |
| Gene name | diacylglycerol kinase gamma | tectonin beta-propeller repeat containing 2 | |
| Synonyms | DAGK3|DGK-GAMMA | KIAA0329|SPG49 | |
| Cytomap | 3q27.2-q27.3 | 14q32.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | diacylglycerol kinase gammaDAG kinase gammadiacylglycerol kinase, gamma 90kDadiacylglyerol kinase gammadiglyceride kinase gamma | tectonin beta-propeller repeat-containing protein 2 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | P49619 | O15040 | |
| Ensembl transtripts involved in fusion gene | ENST00000447054, ENST00000265022, ENST00000344484, ENST00000382164, ENST00000544847, | ENST00000359520, ENST00000561228, ENST00000558678, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 4 X 3 X 6=72 |
| # samples | 4 | 6 | |
| ** MAII score | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(6/72*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DGKG [Title/Abstract] AND TECPR2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DGKG | GO:0046486 | glycerolipid metabolic process | 22627129 |
| Hgene | DGKG | GO:0046834 | lipid phosphorylation | 22627129 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF902754 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000447054 | ENST00000359520 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000447054 | ENST00000561228 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000447054 | ENST00000558678 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000265022 | ENST00000359520 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000265022 | ENST00000561228 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000265022 | ENST00000558678 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000344484 | ENST00000359520 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000344484 | ENST00000561228 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000344484 | ENST00000558678 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000382164 | ENST00000359520 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000382164 | ENST00000561228 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000382164 | ENST00000558678 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000544847 | ENST00000359520 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000544847 | ENST00000561228 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
| intron-intron | ENST00000544847 | ENST00000558678 | DGKG | chr3 | 185882770 | - | TECPR2 | chr14 | 102846174 | - |
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FusionProtFeatures for DGKG_TECPR2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DGKG | TECPR2 |