|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 9512 |
FusionGeneSummary for DDC_KIAA0040 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DDC_KIAA0040 | Fusion gene ID: 9512 | Hgene | Tgene | Gene symbol | DDC | KIAA0040 | Gene ID | 1644 | 9674 |
| Gene name | dopa decarboxylase | KIAA0040 | |
| Synonyms | AADC | - | |
| Cytomap | 7p12.2-p12.1 | 1q25.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | aromatic-L-amino-acid decarboxylasedopa decarboxylase (aromatic L-amino acid decarboxylase) | uncharacterized protein KIAA0040 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | P20711 | ||
| Ensembl transtripts involved in fusion gene | ENST00000357936, ENST00000431062, ENST00000426377, ENST00000444124, ENST00000380984, ENST00000489162, | ENST00000423313, ENST00000444639, ENST00000545251, ENST00000567124, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 2 X 2 X 2=8 |
| # samples | 1 | 2 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: DDC [Title/Abstract] AND KIAA0040 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUAD | TCGA-55-8620-01A | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000357936 | ENST00000423313 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000357936 | ENST00000444639 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000357936 | ENST00000545251 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000357936 | ENST00000567124 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000431062 | ENST00000423313 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000431062 | ENST00000444639 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000431062 | ENST00000545251 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000431062 | ENST00000567124 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000426377 | ENST00000423313 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000426377 | ENST00000444639 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000426377 | ENST00000545251 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000426377 | ENST00000567124 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000444124 | ENST00000423313 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000444124 | ENST00000444639 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000444124 | ENST00000545251 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000444124 | ENST00000567124 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000380984 | ENST00000423313 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000380984 | ENST00000444639 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000380984 | ENST00000545251 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| 5CDS-5UTR | ENST00000380984 | ENST00000567124 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| intron-5UTR | ENST00000489162 | ENST00000423313 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| intron-5UTR | ENST00000489162 | ENST00000444639 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| intron-5UTR | ENST00000489162 | ENST00000545251 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
| intron-5UTR | ENST00000489162 | ENST00000567124 | DDC | chr7 | 50571691 | - | KIAA0040 | chr1 | 175135873 | - |
Top |
FusionProtFeatures for DDC_KIAA0040 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DDC | KIAA0040 |