	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 9280

FusionGeneSummary for DAP3_ATP8B2

Fusion gene summary

Fusion gene information	Fusion gene name: DAP3_ATP8B2
	Fusion gene ID: 9280
		Hgene	Tgene
	Gene symbol	DAP3	ATP8B2
	Gene ID	58512	57198
	Gene name	DLG associated protein 3	ATPase phospholipid transporting 8B2
	Synonyms	DAP3\|SAPAP3	ATPID
	Cytomap	1p34.3	1q21.3
	Type of gene	protein-coding	protein-coding
	Description	disks large-associated protein 3DAP-3PSD-95/SAP90-binding protein 3SAP90/PSD-95-associated protein 3discs large homolog associated protein 3	phospholipid-transporting ATPase ID36/8-9 fusion protein with epitope for anti-lectin antibodyATPase, aminophospholipid transporter, class I, type 8B, member 2ATPase, class I, type 8B, member 2P4-ATPase flippase complex alpha subunit ATP8B2probable p
	Modification date	20180519	20180523
	UniProtAcc	P51398	P98198
	Ensembl transtripts involved in fusion gene	ENST00000471642, ENST00000368336, ENST00000343043, ENST00000496863, ENST00000535183, ENST00000421487, ENST00000465375,	ENST00000368487, ENST00000368489, ENST00000426445, ENST00000341822,
Fusion gene scores	* DoF score	5 X 5 X 4=100	1 X 1 X 1=1
	# samples	5	1
	** MAII score	log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(1/1*10)=3.32192809488736
Context	PubMed: DAP3 [Title/Abstract] AND ATP8B2 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
TCGA	LD	PRAD	TCGA-G9-6363-01A	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5UTR-intron	ENST00000471642	ENST00000368487	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000471642	ENST00000368489	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000471642	ENST00000426445	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000471642	ENST00000341822	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000368336	ENST00000368487	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000368336	ENST00000368489	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000368336	ENST00000426445	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000368336	ENST00000341822	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000343043	ENST00000368487	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000343043	ENST00000368489	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000343043	ENST00000426445	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000343043	ENST00000341822	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
3UTR-intron	ENST00000496863	ENST00000368487	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
3UTR-intron	ENST00000496863	ENST00000368489	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
3UTR-intron	ENST00000496863	ENST00000426445	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
3UTR-intron	ENST00000496863	ENST00000341822	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000535183	ENST00000368487	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000535183	ENST00000368489	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000535183	ENST00000426445	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000535183	ENST00000341822	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000421487	ENST00000368487	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000421487	ENST00000368489	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000421487	ENST00000426445	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000421487	ENST00000341822	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000465375	ENST00000368487	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000465375	ENST00000368489	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000465375	ENST00000426445	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+
5UTR-intron	ENST00000465375	ENST00000341822	DAP3	chr1	155658965	+	ATP8B2	chr1	154317447	+

Top

FusionProtFeatures for DAP3_ATP8B2

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
DAP3 P51398	ATP8B2 P98198

Home

Download

Statistics

Examples

Help

Contact

Fusion gene ID: 9280

FusionGeneSummary for DAP3_ATP8B2

FusionProtFeatures for DAP3_ATP8B2