|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 9044 |
FusionGeneSummary for CWC27_CWC27 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CWC27_CWC27 | Fusion gene ID: 9044 | Hgene | Tgene | Gene symbol | CWC27 | CWC27 | Gene ID | 10283 | 10283 |
| Gene name | CWC27 spliceosome associated protein homolog | CWC27 spliceosome associated protein homolog | |
| Synonyms | NY-CO-10|RPSKA|SDCCAG-10|SDCCAG10 | NY-CO-10|RPSKA|SDCCAG-10|SDCCAG10 | |
| Cytomap | 5q12.3 | 5q12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | peptidyl-prolyl cis-trans isomerase CWC27 homologPPIase CWC27PPIase SDCCAG10antigen NY-CO-10peptidyl-prolyl cis-trans isomerase SDCCAG10serologically defined colon cancer antigen 10 | peptidyl-prolyl cis-trans isomerase CWC27 homologPPIase CWC27PPIase SDCCAG10antigen NY-CO-10peptidyl-prolyl cis-trans isomerase SDCCAG10serologically defined colon cancer antigen 10 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q6UX04 | Q6UX04 | |
| Ensembl transtripts involved in fusion gene | ENST00000381070, ENST00000508024, ENST00000545000, | ENST00000381070, ENST00000508024, ENST00000545000, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 4 X 3 X 3=36 |
| # samples | 1 | 4 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: CWC27 [Title/Abstract] AND CWC27 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BG170618 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000381070 | ENST00000381070 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
| 5UTR-3CDS | ENST00000381070 | ENST00000508024 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
| 5UTR-intron | ENST00000381070 | ENST00000545000 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
| 5UTR-3CDS | ENST00000508024 | ENST00000381070 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
| 5UTR-3CDS | ENST00000508024 | ENST00000508024 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
| 5UTR-intron | ENST00000508024 | ENST00000545000 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
| intron-3CDS | ENST00000545000 | ENST00000381070 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
| intron-3CDS | ENST00000545000 | ENST00000508024 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
| intron-intron | ENST00000545000 | ENST00000545000 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
Top |
FusionProtFeatures for CWC27_CWC27 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CWC27 | CWC27 |