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Fusion gene ID: 8818 |
FusionGeneSummary for CTNNA2_RNU5F-1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CTNNA2_RNU5F-1 | Fusion gene ID: 8818 | Hgene | Tgene | Gene symbol | CTNNA2 | RNU5F-1 | Gene ID | 1496 | 26828 |
| Gene name | catenin alpha 2 | RNA, U5F small nuclear 1 | |
| Synonyms | CAP-R|CAPR|CT114|CTNR | RNU5F|U5F | |
| Cytomap | 2p12 | 1p34.1 | |
| Type of gene | protein-coding | snRNA | |
| Description | catenin alpha-2alpha-N-cateninalpha-catenin-related proteincadherin-associated protein, relatedcancer/testis antigen 114catenin (cadherin-associated protein), alpha 2 | - | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | P26232 | ||
| Ensembl transtripts involved in fusion gene | ENST00000466387, ENST00000496558, ENST00000361291, ENST00000402739, ENST00000540488, ENST00000541047, ENST00000343114, ENST00000496251, ENST00000409266, | ENST00000362507, | |
| Fusion gene scores | * DoF score | 4 X 5 X 2=40 | 5 X 6 X 1=30 |
| # samples | 5 | 6 | |
| ** MAII score | log2(5/40*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(6/30*10)=1 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: CTNNA2 [Title/Abstract] AND RNU5F-1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BM666334 | CTNNA2 | chr2 | 79664036 | - | RNU5F-1 | chr1 | 220238518 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000466387 | ENST00000362507 | CTNNA2 | chr2 | 79664036 | - | RNU5F-1 | chr1 | 220238518 | + |
| intron-intron | ENST00000496558 | ENST00000362507 | CTNNA2 | chr2 | 79664036 | - | RNU5F-1 | chr1 | 220238518 | + |
| intron-intron | ENST00000361291 | ENST00000362507 | CTNNA2 | chr2 | 79664036 | - | RNU5F-1 | chr1 | 220238518 | + |
| intron-intron | ENST00000402739 | ENST00000362507 | CTNNA2 | chr2 | 79664036 | - | RNU5F-1 | chr1 | 220238518 | + |
| intron-intron | ENST00000540488 | ENST00000362507 | CTNNA2 | chr2 | 79664036 | - | RNU5F-1 | chr1 | 220238518 | + |
| intron-intron | ENST00000541047 | ENST00000362507 | CTNNA2 | chr2 | 79664036 | - | RNU5F-1 | chr1 | 220238518 | + |
| intron-intron | ENST00000343114 | ENST00000362507 | CTNNA2 | chr2 | 79664036 | - | RNU5F-1 | chr1 | 220238518 | + |
| intron-intron | ENST00000496251 | ENST00000362507 | CTNNA2 | chr2 | 79664036 | - | RNU5F-1 | chr1 | 220238518 | + |
| intron-intron | ENST00000409266 | ENST00000362507 | CTNNA2 | chr2 | 79664036 | - | RNU5F-1 | chr1 | 220238518 | + |
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FusionProtFeatures for CTNNA2_RNU5F-1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CTNNA2 | RNU5F-1 |