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Fusion gene ID: 8708 |
FusionGeneSummary for CSTF2_CSTF2 |
Fusion gene summary |
| Fusion gene information | Fusion gene name: CSTF2_CSTF2 | Fusion gene ID: 8708 | Hgene | Tgene | Gene symbol | CSTF2 | CSTF2 | Gene ID | 1478 | 1478 |
| Gene name | cleavage stimulation factor subunit 2 | cleavage stimulation factor subunit 2 | |
| Synonyms | CstF-64 | CstF-64 | |
| Cytomap | Xq22.1 | Xq22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cleavage stimulation factor subunit 2CF-1 64 kDa subunitCSTF 64 kDa subunitbetaCstF-64 variant 2cleavage stimulation factor 64 kDa subunitcleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDcleavage stimulation factor, 3' pre-RNA, subunit 2, 64k | cleavage stimulation factor subunit 2CF-1 64 kDa subunitCSTF 64 kDa subunitbetaCstF-64 variant 2cleavage stimulation factor 64 kDa subunitcleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDcleavage stimulation factor, 3' pre-RNA, subunit 2, 64k | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P33240 | P33240 | |
| Ensembl transtripts involved in fusion gene | ENST00000415585, ENST00000372972, | ENST00000415585, ENST00000372972, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 2 X 2 X 1=4 |
| # samples | 1 | 2 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: CSTF2 [Title/Abstract] AND CSTF2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AA653671 | CSTF2 | chrX | 100095725 | - | CSTF2 | chrX | 100093304 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000415585 | ENST00000415585 | CSTF2 | chrX | 100095725 | - | CSTF2 | chrX | 100093304 | + |
| 3UTR-3CDS | ENST00000415585 | ENST00000372972 | CSTF2 | chrX | 100095725 | - | CSTF2 | chrX | 100093304 | + |
| 3UTR-3CDS | ENST00000372972 | ENST00000415585 | CSTF2 | chrX | 100095725 | - | CSTF2 | chrX | 100093304 | + |
| 3UTR-3CDS | ENST00000372972 | ENST00000372972 | CSTF2 | chrX | 100095725 | - | CSTF2 | chrX | 100093304 | + |
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FusionProtFeatures for CSTF2_CSTF2 |
Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CSTF2 | CSTF2 |