FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 8708

FusionGeneSummary for CSTF2_CSTF2

check button Fusion gene summary
Fusion gene informationFusion gene name: CSTF2_CSTF2
Fusion gene ID: 8708
HgeneTgene
Gene symbol

CSTF2

CSTF2

Gene ID

1478

1478

Gene namecleavage stimulation factor subunit 2cleavage stimulation factor subunit 2
SynonymsCstF-64CstF-64
Cytomap

Xq22.1

Xq22.1

Type of geneprotein-codingprotein-coding
Descriptioncleavage stimulation factor subunit 2CF-1 64 kDa subunitCSTF 64 kDa subunitbetaCstF-64 variant 2cleavage stimulation factor 64 kDa subunitcleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDcleavage stimulation factor, 3' pre-RNA, subunit 2, 64kcleavage stimulation factor subunit 2CF-1 64 kDa subunitCSTF 64 kDa subunitbetaCstF-64 variant 2cleavage stimulation factor 64 kDa subunitcleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDcleavage stimulation factor, 3' pre-RNA, subunit 2, 64k
Modification date2018052320180523
UniProtAcc

P33240

P33240

Ensembl transtripts involved in fusion geneENST00000415585, ENST00000372972, 
ENST00000415585, ENST00000372972, 
Fusion gene scores* DoF score1 X 1 X 1=12 X 2 X 1=4
# samples 12
** MAII scorelog2(1/1*10)=3.32192809488736log2(2/4*10)=2.32192809488736
Context

PubMed: CSTF2 [Title/Abstract] AND CSTF2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1AA653671CSTF2chrX

100095725

-CSTF2chrX

100093304

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000415585ENST00000415585CSTF2chrX

100095725

-CSTF2chrX

100093304

+
3UTR-3CDSENST00000415585ENST00000372972CSTF2chrX

100095725

-CSTF2chrX

100093304

+
3UTR-3CDSENST00000372972ENST00000415585CSTF2chrX

100095725

-CSTF2chrX

100093304

+
3UTR-3CDSENST00000372972ENST00000372972CSTF2chrX

100095725

-CSTF2chrX

100093304

+

Top

FusionProtFeatures for CSTF2_CSTF2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CSTF2

P33240

CSTF2

P33240