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Fusion gene ID: 8018 |
FusionGeneSummary for COLEC12_CLUL1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: COLEC12_CLUL1 | Fusion gene ID: 8018 | Hgene | Tgene | Gene symbol | COLEC12 | CLUL1 | Gene ID | 81035 | 27098 |
| Gene name | collectin subfamily member 12 | clusterin like 1 | |
| Synonyms | CLP1|NSR2|SCARA4|SRCL | RA337M | |
| Cytomap | 18p11.32 | 18p11.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | collectin-12collectin placenta protein 1collectin sub-family member 12hCL-P1nurse cell scavenger receptor 2scavenger receptor class A, member 4scavenger receptor with C-type lectin | clusterin-like protein 1clusterin-like 1 (retinal)retinal clusterin-like proteinretinal-specific clusterin-like protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q5KU26 | Q15846 | |
| Ensembl transtripts involved in fusion gene | ENST00000400256, | ENST00000580436, ENST00000400606, ENST00000540035, ENST00000581619, ENST00000338387, ENST00000579494, | |
| Fusion gene scores | * DoF score | 3 X 5 X 3=45 | 3 X 3 X 3=27 |
| # samples | 4 | 3 | |
| ** MAII score | log2(4/45*10)=-0.169925001442312 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: COLEC12 [Title/Abstract] AND CLUL1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | COLEC12 | GO:0006910 | phagocytosis, recognition | 11564734 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LGG | TCGA-HT-8106-01A | COLEC12 | chr18 | 357400 | - | CLUL1 | chr18 | 606978 | + |
| TCGA | LD | LGG | TCGA-HT-8106-01A | COLEC12 | chr18 | 480707 | - | CLUL1 | chr18 | 606978 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000400256 | ENST00000580436 | COLEC12 | chr18 | 357400 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-intron | ENST00000400256 | ENST00000400606 | COLEC12 | chr18 | 357400 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-5UTR | ENST00000400256 | ENST00000540035 | COLEC12 | chr18 | 357400 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-intron | ENST00000400256 | ENST00000581619 | COLEC12 | chr18 | 357400 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-intron | ENST00000400256 | ENST00000338387 | COLEC12 | chr18 | 357400 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-intron | ENST00000400256 | ENST00000579494 | COLEC12 | chr18 | 357400 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-intron | ENST00000400256 | ENST00000580436 | COLEC12 | chr18 | 480707 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-intron | ENST00000400256 | ENST00000400606 | COLEC12 | chr18 | 480707 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-5UTR | ENST00000400256 | ENST00000540035 | COLEC12 | chr18 | 480707 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-intron | ENST00000400256 | ENST00000581619 | COLEC12 | chr18 | 480707 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-intron | ENST00000400256 | ENST00000338387 | COLEC12 | chr18 | 480707 | - | CLUL1 | chr18 | 606978 | + |
| 5CDS-intron | ENST00000400256 | ENST00000579494 | COLEC12 | chr18 | 480707 | - | CLUL1 | chr18 | 606978 | + |
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FusionProtFeatures for COLEC12_CLUL1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| COLEC12 | CLUL1 |