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Fusion gene ID: 7844 |
FusionGeneSummary for COL12A1_TMC5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: COL12A1_TMC5 | Fusion gene ID: 7844 | Hgene | Tgene | Gene symbol | COL12A1 | TMC5 | Gene ID | 1303 | 79838 |
| Gene name | collagen type XII alpha 1 chain | transmembrane channel like 5 | |
| Synonyms | BA209D8.1|BTHLM2|COL12A1L|DJ234P15.1|EDSMYP|UCMD2 | - | |
| Cytomap | 6q13-q14.1 | 16p12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | collagen alpha-1(XII) chaincollagen type XII proteoglycancollagen, type XII, alpha 1 | transmembrane channel-like protein 5 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q99715 | Q6UXY8 | |
| Ensembl transtripts involved in fusion gene | ENST00000322507, ENST00000345356, ENST00000416123, ENST00000483888, ENST00000511023, | ENST00000563675, ENST00000541464, ENST00000381414, ENST00000396229, ENST00000542583, ENST00000219821, ENST00000561503, ENST00000564959, | |
| Fusion gene scores | * DoF score | 4 X 6 X 2=48 | 6 X 8 X 3=144 |
| # samples | 6 | 7 | |
| ** MAII score | log2(6/48*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(7/144*10)=-1.04064198449735 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: COL12A1 [Title/Abstract] AND TMC5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BM987506 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000322507 | ENST00000563675 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000322507 | ENST00000541464 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000322507 | ENST00000381414 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000322507 | ENST00000396229 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000322507 | ENST00000542583 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000322507 | ENST00000219821 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000322507 | ENST00000561503 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000322507 | ENST00000564959 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000345356 | ENST00000563675 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000345356 | ENST00000541464 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000345356 | ENST00000381414 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000345356 | ENST00000396229 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000345356 | ENST00000542583 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000345356 | ENST00000219821 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000345356 | ENST00000561503 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000345356 | ENST00000564959 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000416123 | ENST00000563675 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000416123 | ENST00000541464 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000416123 | ENST00000381414 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000416123 | ENST00000396229 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000416123 | ENST00000542583 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000416123 | ENST00000219821 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000416123 | ENST00000561503 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000416123 | ENST00000564959 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000483888 | ENST00000563675 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000483888 | ENST00000541464 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000483888 | ENST00000381414 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000483888 | ENST00000396229 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000483888 | ENST00000542583 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000483888 | ENST00000219821 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000483888 | ENST00000561503 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000483888 | ENST00000564959 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000511023 | ENST00000563675 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000511023 | ENST00000541464 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000511023 | ENST00000381414 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000511023 | ENST00000396229 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000511023 | ENST00000542583 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000511023 | ENST00000219821 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000511023 | ENST00000561503 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
| intron-intron | ENST00000511023 | ENST00000564959 | COL12A1 | chr6 | 75796003 | + | TMC5 | chr16 | 19462412 | - |
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FusionProtFeatures for COL12A1_TMC5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| COL12A1 | TMC5 |