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Fusion gene ID: 7364 |
FusionGeneSummary for CLEC16A_NBAS |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CLEC16A_NBAS | Fusion gene ID: 7364 | Hgene | Tgene | Gene symbol | CLEC16A | NBAS | Gene ID | 23274 | 51594 |
| Gene name | C-type lectin domain containing 16A | neuroblastoma amplified sequence | |
| Synonyms | Gop-1|KIAA0350 | ILFS2|NAG|SOPH | |
| Cytomap | 16p13.13 | 2p24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein CLEC16AC-type lectin domain family 16 member A | neuroblastoma-amplified sequenceNAG/BC035112 fusionNAG/FAM49A fusionneuroblastoma-amplified gene protein | |
| Modification date | 20180527 | 20180519 | |
| UniProtAcc | Q2KHT3 | A2RRP1 | |
| Ensembl transtripts involved in fusion gene | ENST00000409790, ENST00000409552, ENST00000465491, ENST00000381822, | ENST00000441750, ENST00000281513, | |
| Fusion gene scores | * DoF score | 9 X 7 X 6=378 | 8 X 9 X 3=216 |
| # samples | 12 | 9 | |
| ** MAII score | log2(12/378*10)=-1.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/216*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CLEC16A [Title/Abstract] AND NBAS [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BQ380493 | CLEC16A | chr16 | 11102571 | + | NBAS | chr2 | 15315355 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000409790 | ENST00000441750 | CLEC16A | chr16 | 11102571 | + | NBAS | chr2 | 15315355 | + |
| intron-intron | ENST00000409790 | ENST00000281513 | CLEC16A | chr16 | 11102571 | + | NBAS | chr2 | 15315355 | + |
| intron-intron | ENST00000409552 | ENST00000441750 | CLEC16A | chr16 | 11102571 | + | NBAS | chr2 | 15315355 | + |
| intron-intron | ENST00000409552 | ENST00000281513 | CLEC16A | chr16 | 11102571 | + | NBAS | chr2 | 15315355 | + |
| intron-intron | ENST00000465491 | ENST00000441750 | CLEC16A | chr16 | 11102571 | + | NBAS | chr2 | 15315355 | + |
| intron-intron | ENST00000465491 | ENST00000281513 | CLEC16A | chr16 | 11102571 | + | NBAS | chr2 | 15315355 | + |
| intron-intron | ENST00000381822 | ENST00000441750 | CLEC16A | chr16 | 11102571 | + | NBAS | chr2 | 15315355 | + |
| intron-intron | ENST00000381822 | ENST00000281513 | CLEC16A | chr16 | 11102571 | + | NBAS | chr2 | 15315355 | + |
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FusionProtFeatures for CLEC16A_NBAS |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CLEC16A | NBAS |