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Fusion gene ID: 7279 |
FusionGeneSummary for CKAP5_STATH |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CKAP5_STATH | Fusion gene ID: 7279 | Hgene | Tgene | Gene symbol | CKAP5 | STATH | Gene ID | 9793 | 6779 |
| Gene name | cytoskeleton associated protein 5 | statherin | |
| Synonyms | CHTOG|MSPS|TOG|TOGp|ch-TOG | STR | |
| Cytomap | 11p11.2 | 4q13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cytoskeleton-associated protein 5colonic and hepatic tumor over-expressed gene proteincolonic and hepatic tumor overexpressed gene protein | statherin | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q14008 | P02808 | |
| Ensembl transtripts involved in fusion gene | ENST00000529230, ENST00000415402, ENST00000312055, ENST00000354558, ENST00000532321, | ENST00000246895, ENST00000381060, | |
| Fusion gene scores | * DoF score | 4 X 4 X 4=64 | 2 X 2 X 1=4 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: CKAP5 [Title/Abstract] AND STATH [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AX747668 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-5UTR | ENST00000529230 | ENST00000246895 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
| intron-5UTR | ENST00000529230 | ENST00000381060 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
| intron-5UTR | ENST00000415402 | ENST00000246895 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
| intron-5UTR | ENST00000415402 | ENST00000381060 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
| intron-5UTR | ENST00000312055 | ENST00000246895 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
| intron-5UTR | ENST00000312055 | ENST00000381060 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
| intron-5UTR | ENST00000354558 | ENST00000246895 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
| intron-5UTR | ENST00000354558 | ENST00000381060 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
| intron-5UTR | ENST00000532321 | ENST00000246895 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
| intron-5UTR | ENST00000532321 | ENST00000381060 | CKAP5 | chr11 | 46829625 | - | STATH | chr4 | 70861681 | + |
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FusionProtFeatures for CKAP5_STATH |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CKAP5 | STATH |