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Fusion gene ID: 6689 |
FusionGeneSummary for CDYL_ZZZ3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CDYL_ZZZ3 | Fusion gene ID: 6689 | Hgene | Tgene | Gene symbol | CDYL | ZZZ3 | Gene ID | 9425 | 26009 |
| Gene name | chromodomain Y like | zinc finger ZZ-type containing 3 | |
| Synonyms | CDYL1 | ATAC1 | |
| Cytomap | 6p25.1 | 1p31.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | chromodomain Y-like proteinCDY-like, autosomalchromodomain protein, Y-likecrotonyl-CoA hydratasetestis-specific chromodomain Y-like protein | ZZ-type zinc finger-containing protein 3ATAC component 1 homologzinc finger, ZZ domain containing 3 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9Y232 | Q8IYH5 | |
| Ensembl transtripts involved in fusion gene | ENST00000328908, ENST00000397588, ENST00000472453, ENST00000449732, ENST00000343762, | ENST00000370801, ENST00000370798, ENST00000476275, | |
| Fusion gene scores | * DoF score | 8 X 8 X 2=128 | 3 X 2 X 1=6 |
| # samples | 14 | 3 | |
| ** MAII score | log2(14/128*10)=0.129283016944966 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/6*10)=2.32192809488736 | |
| Context | PubMed: CDYL [Title/Abstract] AND ZZZ3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CDYL | GO:0120094 | negative regulation of peptidyl-lysine crotonylation | 28803779 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BE042764 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000328908 | ENST00000370801 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000328908 | ENST00000370798 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000328908 | ENST00000476275 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000397588 | ENST00000370801 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000397588 | ENST00000370798 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000397588 | ENST00000476275 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000472453 | ENST00000370801 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000472453 | ENST00000370798 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000472453 | ENST00000476275 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000449732 | ENST00000370801 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000449732 | ENST00000370798 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000449732 | ENST00000476275 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000343762 | ENST00000370801 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000343762 | ENST00000370798 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
| intron-intron | ENST00000343762 | ENST00000476275 | CDYL | chr6 | 4739546 | + | ZZZ3 | chr1 | 78036110 | + |
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FusionProtFeatures for CDYL_ZZZ3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CDYL | ZZZ3 |