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Fusion gene ID: 6676 |
FusionGeneSummary for CDV3_MBP |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CDV3_MBP | Fusion gene ID: 6676 | Hgene | Tgene | Gene symbol | CDV3 | MBP | Gene ID | 55573 | 5553 |
| Gene name | CDV3 homolog | proteoglycan 2, pro eosinophil major basic protein | |
| Synonyms | H41 | BMPG|MBP|MBP1|proMBP | |
| Cytomap | 3q22.1 | 11q12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein CDV3 homologcarnitine deficiency-associated gene expressed in ventricle 3 | bone marrow proteoglycaneosinophil granule major basic proteineosinophil major basic proteinnatural killer cell activatorproteoglycan 2 preproproteinproteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q9UKY7 | P02686 | |
| Ensembl transtripts involved in fusion gene | ENST00000264993, ENST00000431519, ENST00000508481, ENST00000420115, ENST00000511392, ENST00000515421, | ENST00000382582, ENST00000355994, ENST00000397875, ENST00000397866, ENST00000397865, ENST00000527041, ENST00000359645, ENST00000528160, ENST00000397869, ENST00000354542, ENST00000526111, ENST00000580402, ENST00000579129, ENST00000578193, ENST00000397863, ENST00000397860, ENST00000487778, | |
| Fusion gene scores | * DoF score | 4 X 3 X 3=36 | 26 X 20 X 3=1560 |
| # samples | 4 | 27 | |
| ** MAII score | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(27/1560*10)=-2.53051471669878 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CDV3 [Title/Abstract] AND MBP [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DA349409 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-5UTR | ENST00000264993 | ENST00000382582 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000355994 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000397875 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000397866 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000397865 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000527041 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-intron | ENST00000264993 | ENST00000359645 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000528160 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000397869 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000354542 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000526111 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000580402 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000579129 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000578193 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000397863 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000397860 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000264993 | ENST00000487778 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000382582 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000355994 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000397875 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000397866 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000397865 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000527041 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-intron | ENST00000431519 | ENST00000359645 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000528160 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000397869 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000354542 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000526111 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000580402 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000579129 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000578193 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000397863 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000397860 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000431519 | ENST00000487778 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000382582 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000355994 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000397875 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000397866 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000397865 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000527041 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-intron | ENST00000508481 | ENST00000359645 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000528160 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000397869 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000354542 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000526111 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000580402 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000579129 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000578193 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000397863 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000397860 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000508481 | ENST00000487778 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000382582 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000355994 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000397875 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000397866 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000397865 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000527041 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-intron | ENST00000420115 | ENST00000359645 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000528160 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000397869 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000354542 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000526111 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000580402 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000579129 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000578193 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000397863 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000397860 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000420115 | ENST00000487778 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000382582 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000355994 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000397875 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000397866 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000397865 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000527041 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-intron | ENST00000511392 | ENST00000359645 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000528160 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000397869 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000354542 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000526111 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000580402 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000579129 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000578193 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000397863 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000397860 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000511392 | ENST00000487778 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000382582 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000355994 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000397875 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000397866 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000397865 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000527041 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-intron | ENST00000515421 | ENST00000359645 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000528160 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000397869 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000354542 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000526111 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000580402 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000579129 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000578193 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000397863 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000397860 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
| intron-5UTR | ENST00000515421 | ENST00000487778 | CDV3 | chr3 | 133297269 | + | MBP | chr18 | 74729011 | - |
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FusionProtFeatures for CDV3_MBP |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CDV3 | MBP |