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Fusion gene ID: 6652 |
FusionGeneSummary for CDR1_AIF1L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CDR1_AIF1L | Fusion gene ID: 6652 | Hgene | Tgene | Gene symbol | CDR1 | AIF1L | Gene ID | 1038 | 83543 |
| Gene name | cerebellar degeneration related protein 1 | allograft inflammatory factor 1 like | |
| Synonyms | CDR|CDR34|CDR62A | C9orf58|IBA2 | |
| Cytomap | Xq27.1 | 9q34.12-q34.13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cerebellar degeneration-related antigen 1cerebellar degeneration-related protein 1, 34kDa | allograft inflammatory factor 1-likeionized calcium binding adapter molecule 2 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | P51861 | Q9BQI0 | |
| Ensembl transtripts involved in fusion gene | ENST00000370532, | ENST00000372309, ENST00000372302, ENST00000247291, ENST00000372300, ENST00000472942, ENST00000372298, ENST00000372297, ENST00000372312, ENST00000372301, | |
| Fusion gene scores | * DoF score | 4 X 6 X 1=24 | 2 X 2 X 2=8 |
| # samples | 25 | 2 | |
| ** MAII score | log2(25/24*10)=3.38082178394093 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: CDR1 [Title/Abstract] AND AIF1L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DA389009 | CDR1 | chrX | 139866784 | + | AIF1L | chr9 | 133971918 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-5UTR | ENST00000370532 | ENST00000372309 | CDR1 | chrX | 139866784 | + | AIF1L | chr9 | 133971918 | + |
| intron-intron | ENST00000370532 | ENST00000372302 | CDR1 | chrX | 139866784 | + | AIF1L | chr9 | 133971918 | + |
| intron-intron | ENST00000370532 | ENST00000247291 | CDR1 | chrX | 139866784 | + | AIF1L | chr9 | 133971918 | + |
| intron-intron | ENST00000370532 | ENST00000372300 | CDR1 | chrX | 139866784 | + | AIF1L | chr9 | 133971918 | + |
| intron-intron | ENST00000370532 | ENST00000472942 | CDR1 | chrX | 139866784 | + | AIF1L | chr9 | 133971918 | + |
| intron-intron | ENST00000370532 | ENST00000372298 | CDR1 | chrX | 139866784 | + | AIF1L | chr9 | 133971918 | + |
| intron-intron | ENST00000370532 | ENST00000372297 | CDR1 | chrX | 139866784 | + | AIF1L | chr9 | 133971918 | + |
| intron-intron | ENST00000370532 | ENST00000372312 | CDR1 | chrX | 139866784 | + | AIF1L | chr9 | 133971918 | + |
| intron-intron | ENST00000370532 | ENST00000372301 | CDR1 | chrX | 139866784 | + | AIF1L | chr9 | 133971918 | + |
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FusionProtFeatures for CDR1_AIF1L |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CDR1 | AIF1L |