|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 6134 |
FusionGeneSummary for CD164_PNRC1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CD164_PNRC1 | Fusion gene ID: 6134 | Hgene | Tgene | Gene symbol | CD164 | PNRC1 | Gene ID | 8763 | 10957 |
| Gene name | CD164 molecule | proline rich nuclear receptor coactivator 1 | |
| Synonyms | DFNA66|MGC-24|MGC-24v|MUC-24|endolyn | B4-2|PNAS-145|PROL2|PRR2 | |
| Cytomap | 6q21 | 6q15 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sialomucin core protein 24CD164 antigen, sialomucinmulti-glycosylated core protein 24 | proline-rich nuclear receptor coactivator 1proline rich 2 proteinproline-rich polypeptide 2proline-rich protein 2proline-rich protein with nuclear targeting signalprotein B4-2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q04900 | Q12796 | |
| Ensembl transtripts involved in fusion gene | ENST00000413644, ENST00000368961, ENST00000310786, ENST00000275080, ENST00000324953, ENST00000512821, ENST00000504373, ENST00000506649, | ENST00000369472, ENST00000336032, ENST00000354922, | |
| Fusion gene scores | * DoF score | 3 X 3 X 1=9 | 2 X 2 X 1=4 |
| # samples | 3 | 2 | |
| ** MAII score | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: CD164 [Title/Abstract] AND PNRC1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CD164 | GO:0007155 | cell adhesion | 10491205 |
| Hgene | CD164 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | 10491205 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BU655987 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000413644 | ENST00000369472 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000413644 | ENST00000336032 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000413644 | ENST00000354922 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000368961 | ENST00000369472 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000368961 | ENST00000336032 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000368961 | ENST00000354922 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000310786 | ENST00000369472 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000310786 | ENST00000336032 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000310786 | ENST00000354922 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000275080 | ENST00000369472 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000275080 | ENST00000336032 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000275080 | ENST00000354922 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000324953 | ENST00000369472 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000324953 | ENST00000336032 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000324953 | ENST00000354922 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000512821 | ENST00000369472 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000512821 | ENST00000336032 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| 5CDS-5UTR | ENST00000512821 | ENST00000354922 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| intron-5UTR | ENST00000504373 | ENST00000369472 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| intron-5UTR | ENST00000504373 | ENST00000336032 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| intron-5UTR | ENST00000504373 | ENST00000354922 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| intron-5UTR | ENST00000506649 | ENST00000369472 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| intron-5UTR | ENST00000506649 | ENST00000336032 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
| intron-5UTR | ENST00000506649 | ENST00000354922 | CD164 | chr6 | 109703405 | - | PNRC1 | chr6 | 89793470 | + |
Top |
FusionProtFeatures for CD164_PNRC1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CD164 | PNRC1 |