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Fusion gene ID: 6095 |
FusionGeneSummary for CCT3_GON4L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CCT3_GON4L | Fusion gene ID: 6095 | Hgene | Tgene | Gene symbol | CCT3 | GON4L | Gene ID | 7203 | 54856 |
| Gene name | chaperonin containing TCP1 subunit 3 | gon-4 like | |
| Synonyms | CCT-gamma|CCTG|PIG48|TCP-1-gamma|TRIC5 | GON-4|GON4|YARP | |
| Cytomap | 1q22 | 1q22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | T-complex protein 1 subunit gammaT-complex protein 1, gamma subunitTCP1 (t-complex-1) ring complex, polypeptide 5chaperonin containing TCP1, subunit 3 (gamma)hTRiC5 | GON-4-like protein2610100B20RikYY1AP related proteinYY1AP-related protein1gon-4 homolog | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P49368 | Q3T8J9 | |
| Ensembl transtripts involved in fusion gene | ENST00000295688, ENST00000368259, ENST00000368261, ENST00000472765, ENST00000368256, | ENST00000437809, ENST00000368331, ENST00000271883, ENST00000361040, ENST00000471341, | |
| Fusion gene scores | * DoF score | 16 X 10 X 9=1440 | 7 X 6 X 6=252 |
| # samples | 17 | 8 | |
| ** MAII score | log2(17/1440*10)=-3.08246216019197 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/252*10)=-1.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CCT3 [Title/Abstract] AND GON4L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | PRAD | TCGA-HC-8262-01A | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000295688 | ENST00000437809 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000295688 | ENST00000368331 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000295688 | ENST00000271883 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000295688 | ENST00000361040 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000295688 | ENST00000471341 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000368259 | ENST00000437809 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000368259 | ENST00000368331 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000368259 | ENST00000271883 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000368259 | ENST00000361040 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000368259 | ENST00000471341 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000368261 | ENST00000437809 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000368261 | ENST00000368331 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000368261 | ENST00000271883 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000368261 | ENST00000361040 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000368261 | ENST00000471341 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000472765 | ENST00000437809 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000472765 | ENST00000368331 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000472765 | ENST00000271883 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000472765 | ENST00000361040 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5CDS-intron | ENST00000472765 | ENST00000471341 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5UTR-intron | ENST00000368256 | ENST00000437809 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5UTR-intron | ENST00000368256 | ENST00000368331 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5UTR-intron | ENST00000368256 | ENST00000271883 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5UTR-intron | ENST00000368256 | ENST00000361040 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
| 5UTR-intron | ENST00000368256 | ENST00000471341 | CCT3 | chr1 | 156303338 | - | GON4L | chr1 | 155802741 | - |
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FusionProtFeatures for CCT3_GON4L |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CCT3 | GON4L |