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Fusion gene ID: 6056 |
FusionGeneSummary for CCP110_PTMS |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CCP110_PTMS | Fusion gene ID: 6056 | Hgene | Tgene | Gene symbol | CCP110 | PTMS | Gene ID | 9738 | 5763 |
| Gene name | centriolar coiled-coil protein 110 | parathymosin | |
| Synonyms | CP110|Cep110 | ParaT | |
| Cytomap | 16p12.3 | 12p13.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | centriolar coiled-coil protein of 110 kDacentriolar coiled-coil protein 110kDacentrosomal protein CP110centrosomal protein of 110 kDa | parathymosin | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | O43303 | P20962 | |
| Ensembl transtripts involved in fusion gene | ENST00000396212, ENST00000381396, ENST00000573412, ENST00000396208, | ENST00000389462, ENST00000309083, ENST00000538057, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 7 X 6 X 3=126 |
| # samples | 2 | 7 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CCP110 [Title/Abstract] AND PTMS [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CCP110 | GO:0051298 | centrosome duplication | 20596027 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BM041237 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-intron | ENST00000396212 | ENST00000389462 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 5UTR-3UTR | ENST00000396212 | ENST00000309083 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 5UTR-3UTR | ENST00000396212 | ENST00000538057 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 5UTR-intron | ENST00000381396 | ENST00000389462 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 5UTR-3UTR | ENST00000381396 | ENST00000309083 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 5UTR-3UTR | ENST00000381396 | ENST00000538057 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 3UTR-intron | ENST00000573412 | ENST00000389462 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 3UTR-3UTR | ENST00000573412 | ENST00000309083 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 3UTR-3UTR | ENST00000573412 | ENST00000538057 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 5UTR-intron | ENST00000396208 | ENST00000389462 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 5UTR-3UTR | ENST00000396208 | ENST00000309083 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
| 5UTR-3UTR | ENST00000396208 | ENST00000538057 | CCP110 | chr16 | 19535330 | + | PTMS | chr12 | 6879720 | + |
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FusionProtFeatures for CCP110_PTMS |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CCP110 | PTMS |