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Fusion gene ID: 5889 |
FusionGeneSummary for CCDC69_SLC35D2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CCDC69_SLC35D2 | Fusion gene ID: 5889 | Hgene | Tgene | Gene symbol | CCDC69 | SLC35D2 | Gene ID | 26112 | 11046 |
| Gene name | coiled-coil domain containing 69 | solute carrier family 35 member D2 | |
| Synonyms | - | HFRC1|SQV7L|UGTrel8|hfrc | |
| Cytomap | 5q33.1 | 9q22.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | coiled-coil domain-containing protein 69 | UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporterSQV7-like proteinUDP-N-acetylglucosamine transporterUDP-galactose transporter-related protein 8fringe connectionhomolog of Fringe connection protein 1solute carrier family 35 (UDP-GlcNAc/UDP | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | A6NI79 | Q76EJ3 | |
| Ensembl transtripts involved in fusion gene | ENST00000521308, ENST00000355417, | ENST00000253270, ENST00000375259, ENST00000375257, ENST00000482643, | |
| Fusion gene scores | * DoF score | 4 X 4 X 1=16 | 3 X 3 X 3=27 |
| # samples | 5 | 3 | |
| ** MAII score | log2(5/16*10)=1.64385618977472 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: CCDC69 [Title/Abstract] AND SLC35D2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF085006 | CCDC69 | chr5 | 150581162 | + | SLC35D2 | chr9 | 99113415 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000521308 | ENST00000253270 | CCDC69 | chr5 | 150581162 | + | SLC35D2 | chr9 | 99113415 | - |
| intron-3CDS | ENST00000521308 | ENST00000375259 | CCDC69 | chr5 | 150581162 | + | SLC35D2 | chr9 | 99113415 | - |
| intron-3CDS | ENST00000521308 | ENST00000375257 | CCDC69 | chr5 | 150581162 | + | SLC35D2 | chr9 | 99113415 | - |
| intron-5UTR | ENST00000521308 | ENST00000482643 | CCDC69 | chr5 | 150581162 | + | SLC35D2 | chr9 | 99113415 | - |
| intron-3CDS | ENST00000355417 | ENST00000253270 | CCDC69 | chr5 | 150581162 | + | SLC35D2 | chr9 | 99113415 | - |
| intron-3CDS | ENST00000355417 | ENST00000375259 | CCDC69 | chr5 | 150581162 | + | SLC35D2 | chr9 | 99113415 | - |
| intron-3CDS | ENST00000355417 | ENST00000375257 | CCDC69 | chr5 | 150581162 | + | SLC35D2 | chr9 | 99113415 | - |
| intron-5UTR | ENST00000355417 | ENST00000482643 | CCDC69 | chr5 | 150581162 | + | SLC35D2 | chr9 | 99113415 | - |
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FusionProtFeatures for CCDC69_SLC35D2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CCDC69 | SLC35D2 |