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Fusion gene ID: 5865 |
FusionGeneSummary for CCDC53_C19orf48 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CCDC53_C19orf48 | Fusion gene ID: 5865 | Hgene | Tgene | Gene symbol | CCDC53 | C19orf48 | Gene ID | 51019 | 84798 |
| Gene name | WASH complex subunit 3 | chromosome 19 open reading frame 48 | |
| Synonyms | CCDC53|CGI-116 | - | |
| Cytomap | 12q23.2 | 19q13.33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | WASH complex subunit 3WASH complex subunit CCDC53coiled-coil domain containing 53coiled-coil domain-containing protein 53 | uncharacterized protein C19orf48multidrug resistance-related protein | |
| Modification date | 20180522 | 20180329 | |
| UniProtAcc | Q6RUI8 | ||
| Ensembl transtripts involved in fusion gene | ENST00000240079, ENST00000545679, ENST00000539515, | ENST00000598463, ENST00000345523, ENST00000391812, ENST00000596655, ENST00000595794, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 2 X 2 X 2=8 |
| # samples | 1 | 2 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: CCDC53 [Title/Abstract] AND C19orf48 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF921302 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-5UTR | ENST00000240079 | ENST00000598463 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000240079 | ENST00000345523 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000240079 | ENST00000391812 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000240079 | ENST00000596655 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000240079 | ENST00000595794 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000545679 | ENST00000598463 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000545679 | ENST00000345523 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000545679 | ENST00000391812 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000545679 | ENST00000596655 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000545679 | ENST00000595794 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000539515 | ENST00000598463 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000539515 | ENST00000345523 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000539515 | ENST00000391812 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000539515 | ENST00000596655 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
| intron-5UTR | ENST00000539515 | ENST00000595794 | CCDC53 | chr12 | 102455797 | + | C19orf48 | chr19 | 51302029 | - |
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FusionProtFeatures for CCDC53_C19orf48 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CCDC53 | C19orf48 |