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Fusion gene ID: 5827 |
FusionGeneSummary for CCDC175_TNFRSF25 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CCDC175_TNFRSF25 | Fusion gene ID: 5827 | Hgene | Tgene | Gene symbol | CCDC175 | TNFRSF25 | Gene ID | 729665 | 8718 |
| Gene name | coiled-coil domain containing 175 | TNF receptor superfamily member 25 | |
| Synonyms | C14orf38|c14_5395 | APO-3|DDR3|DR3|LARD|TNFRSF12|TR3|TRAMP|WSL-1|WSL-LR | |
| Cytomap | 14q23.1 | 1p36.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | coiled-coil domain-containing protein 175 | tumor necrosis factor receptor superfamily member 25apoptosis inducing receptorapoptosis-inducing receptor AIRapoptosis-mediating receptor DR3apoptosis-mediating receptor TRAMPdeath domain receptor 3 soluble formdeath receptor betalymphocyte-associ | |
| Modification date | 20180403 | 20180522 | |
| UniProtAcc | P0C221 | Q93038 | |
| Ensembl transtripts involved in fusion gene | ENST00000537690, ENST00000281581, ENST00000556996, | ENST00000377782, ENST00000356876, ENST00000351959, ENST00000351748, ENST00000348333, ENST00000461703, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
| # samples | 1 | 1 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: CCDC175 [Title/Abstract] AND TNFRSF25 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AK094488 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000537690 | ENST00000377782 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000537690 | ENST00000356876 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000537690 | ENST00000351959 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000537690 | ENST00000351748 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000537690 | ENST00000348333 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000537690 | ENST00000461703 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000281581 | ENST00000377782 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000281581 | ENST00000356876 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000281581 | ENST00000351959 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000281581 | ENST00000351748 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000281581 | ENST00000348333 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000281581 | ENST00000461703 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000556996 | ENST00000377782 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000556996 | ENST00000356876 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000556996 | ENST00000351959 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000556996 | ENST00000351748 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000556996 | ENST00000348333 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
| intron-intron | ENST00000556996 | ENST00000461703 | CCDC175 | chr14 | 60017911 | - | TNFRSF25 | chr1 | 6523550 | - |
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FusionProtFeatures for CCDC175_TNFRSF25 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CCDC175 | TNFRSF25 |