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Fusion gene ID: 5744 |
FusionGeneSummary for CC2D2A_FANCF |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CC2D2A_FANCF | Fusion gene ID: 5744 | Hgene | Tgene | Gene symbol | CC2D2A | FANCF | Gene ID | 57545 | 2188 |
| Gene name | coiled-coil and C2 domain containing 2A | FA complementation group F | |
| Synonyms | JBTS9|MKS6 | FAF | |
| Cytomap | 4p15.32 | 11p14.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | coiled-coil and C2 domain-containing protein 2A | Fanconi anemia group F proteinFanconi anemia complementation group F | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q9P2K1 | Q9NPI8 | |
| Ensembl transtripts involved in fusion gene | ENST00000424120, ENST00000413206, ENST00000503292, ENST00000389652, ENST00000438599, ENST00000511544, ENST00000513811, ENST00000507954, ENST00000515124, ENST00000503658, | ENST00000327470, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 1 X 1 X 1=1 |
| # samples | 3 | 2 | |
| ** MAII score | log2(3/8*10)=1.90689059560852 | log2(2/1*10)=4.32192809488736 | |
| Context | PubMed: CC2D2A [Title/Abstract] AND FANCF [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BC017792 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - | ||
| ChiTaRS3.1 | BG494289 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000424120 | ENST00000327470 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
| intron-3UTR | ENST00000413206 | ENST00000327470 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
| intron-3UTR | ENST00000503292 | ENST00000327470 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
| intron-3UTR | ENST00000389652 | ENST00000327470 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
| 3UTR-3UTR | ENST00000438599 | ENST00000327470 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
| 3UTR-3UTR | ENST00000511544 | ENST00000327470 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
| intron-3UTR | ENST00000513811 | ENST00000327470 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
| 5CDS-3UTR | ENST00000507954 | ENST00000327470 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
| 5CDS-3UTR | ENST00000515124 | ENST00000327470 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
| 3UTR-3UTR | ENST00000503658 | ENST00000327470 | CC2D2A | chr4 | 15482848 | + | FANCF | chr11 | 22645292 | - |
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FusionProtFeatures for CC2D2A_FANCF |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CC2D2A | FANCF |