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Fusion gene ID: 5078 |
FusionGeneSummary for C7orf25_RALB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: C7orf25_RALB | Fusion gene ID: 5078 | Hgene | Tgene | Gene symbol | C7orf25 | RALB | Gene ID | 79020 | 5899 |
| Gene name | chromosome 7 open reading frame 25 | RAS like proto-oncogene B | |
| Synonyms | - | - | |
| Cytomap | 7p14.1 | 2q14.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | UPF0415 protein C7orf25 | ras-related protein Ral-BRALB Ras like proto-oncogene BRAS-like protein Bras related GTP binding protein Bv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q9BPX7 | P11234 | |
| Ensembl transtripts involved in fusion gene | ENST00000350427, ENST00000447342, ENST00000431882, ENST00000438029, | ENST00000474855, ENST00000272519, ENST00000420510, ENST00000404963, ENST00000470417, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 4 X 4 X 2=32 |
| # samples | 1 | 5 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(5/32*10)=0.643856189774725 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: C7orf25 [Title/Abstract] AND RALB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | RALB | GO:0009267 | cellular response to starvation | 24056301 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AI190624 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000350427 | ENST00000474855 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000350427 | ENST00000272519 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-intron | ENST00000350427 | ENST00000420510 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000350427 | ENST00000404963 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000350427 | ENST00000470417 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-intron | ENST00000447342 | ENST00000474855 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000447342 | ENST00000272519 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-intron | ENST00000447342 | ENST00000420510 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000447342 | ENST00000404963 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000447342 | ENST00000470417 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-intron | ENST00000431882 | ENST00000474855 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000431882 | ENST00000272519 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-intron | ENST00000431882 | ENST00000420510 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000431882 | ENST00000404963 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000431882 | ENST00000470417 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-intron | ENST00000438029 | ENST00000474855 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000438029 | ENST00000272519 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-intron | ENST00000438029 | ENST00000420510 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000438029 | ENST00000404963 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
| intron-3UTR | ENST00000438029 | ENST00000470417 | C7orf25 | chr7 | 42956724 | + | RALB | chr2 | 121052136 | - |
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FusionProtFeatures for C7orf25_RALB |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| C7orf25 | RALB |