|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 4746 |
FusionGeneSummary for C16orf72_ACSM2A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: C16orf72_ACSM2A | Fusion gene ID: 4746 | Hgene | Tgene | Gene symbol | C16orf72 | ACSM2A | Gene ID | 29035 | 123876 |
| Gene name | chromosome 16 open reading frame 72 | acyl-CoA synthetase medium chain family member 2A | |
| Synonyms | PRO0149 | A-923A4.1|ACSM2 | |
| Cytomap | 16p13.2 | 16p12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | UPF0472 protein C16orf72 | acyl-coenzyme A synthetase ACSM2A, mitochondrialacyl-CoA synthetase medium-chain family member 2butyrate--CoA ligase 2Abutyryl-coenzyme A synthetase 2Amiddle-chain acyl-CoA synthetase 2A | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q14CZ0 | Q08AH3 | |
| Ensembl transtripts involved in fusion gene | ENST00000327827, | ENST00000417235, ENST00000424070, ENST00000575558, ENST00000536134, ENST00000573854, ENST00000219054, ENST00000575690, ENST00000396104, | |
| Fusion gene scores | * DoF score | 5 X 5 X 3=75 | 1 X 1 X 1=1 |
| # samples | 6 | 1 | |
| ** MAII score | log2(6/75*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: C16orf72 [Title/Abstract] AND ACSM2A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ACSM2A | GO:0036112 | medium-chain fatty-acyl-CoA metabolic process | 19345228 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-C8-A278-01A | C16orf72 | chr16 | 9186858 | + | ACSM2A | chr16 | 20471429 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000327827 | ENST00000417235 | C16orf72 | chr16 | 9186858 | + | ACSM2A | chr16 | 20471429 | + |
| 5CDS-5UTR | ENST00000327827 | ENST00000424070 | C16orf72 | chr16 | 9186858 | + | ACSM2A | chr16 | 20471429 | + |
| 5CDS-intron | ENST00000327827 | ENST00000575558 | C16orf72 | chr16 | 9186858 | + | ACSM2A | chr16 | 20471429 | + |
| 5CDS-5UTR | ENST00000327827 | ENST00000536134 | C16orf72 | chr16 | 9186858 | + | ACSM2A | chr16 | 20471429 | + |
| 5CDS-5UTR | ENST00000327827 | ENST00000573854 | C16orf72 | chr16 | 9186858 | + | ACSM2A | chr16 | 20471429 | + |
| 5CDS-5UTR | ENST00000327827 | ENST00000219054 | C16orf72 | chr16 | 9186858 | + | ACSM2A | chr16 | 20471429 | + |
| 5CDS-5UTR | ENST00000327827 | ENST00000575690 | C16orf72 | chr16 | 9186858 | + | ACSM2A | chr16 | 20471429 | + |
| 5CDS-5UTR | ENST00000327827 | ENST00000396104 | C16orf72 | chr16 | 9186858 | + | ACSM2A | chr16 | 20471429 | + |
Top |
FusionProtFeatures for C16orf72_ACSM2A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| C16orf72 | ACSM2A |