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Fusion gene ID: 4499 |
FusionGeneSummary for BSG_STAT6 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BSG_STAT6 | Fusion gene ID: 4499 | Hgene | Tgene | Gene symbol | BSG | STAT6 | Gene ID | 682 | 6778 |
| Gene name | basigin (Ok blood group) | signal transducer and activator of transcription 6 | |
| Synonyms | 5F7|CD147|EMMPRIN|EMPRIN|OK|TCSF | D12S1644|IL-4-STAT|STAT6B|STAT6C | |
| Cytomap | 19p13.3 | 12q13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | basiginOK blood group antigencollagenase stimulatory factorextracellular matrix metalloproteinase inducerleukocyte activation antigen M6tumor cell-derived collagenase stimulatory factor | signal transducer and activator of transcription 6STAT, interleukin4-inducedsignal transducer and activator of transcription 6, interleukin-4 inducedtranscription factor IL-4 STAT | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | P35613 | P42226 | |
| Ensembl transtripts involved in fusion gene | ENST00000346916, ENST00000545507, ENST00000333511, ENST00000353555, ENST00000574970, | ENST00000300134, ENST00000538913, ENST00000543873, ENST00000556155, ENST00000537215, ENST00000454075, | |
| Fusion gene scores | * DoF score | 11 X 9 X 7=693 | 37 X 8 X 15=4440 |
| # samples | 17 | 43 | |
| ** MAII score | log2(17/693*10)=-2.02732060599951 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(43/4440*10)=-3.36815111164801 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: BSG [Title/Abstract] AND STAT6 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | STAT6 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 8810328 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | ACC | TCGA-OR-A5J9-01A | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000346916 | ENST00000300134 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000346916 | ENST00000538913 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000346916 | ENST00000543873 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000346916 | ENST00000556155 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000346916 | ENST00000537215 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000346916 | ENST00000454075 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000545507 | ENST00000300134 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000545507 | ENST00000538913 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000545507 | ENST00000543873 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000545507 | ENST00000556155 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000545507 | ENST00000537215 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000545507 | ENST00000454075 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000333511 | ENST00000300134 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000333511 | ENST00000538913 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000333511 | ENST00000543873 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000333511 | ENST00000556155 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000333511 | ENST00000537215 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000333511 | ENST00000454075 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000353555 | ENST00000300134 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000353555 | ENST00000538913 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000353555 | ENST00000543873 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000353555 | ENST00000556155 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000353555 | ENST00000537215 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| 5CDS-intron | ENST00000353555 | ENST00000454075 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| intron-intron | ENST00000574970 | ENST00000300134 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| intron-intron | ENST00000574970 | ENST00000538913 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| intron-intron | ENST00000574970 | ENST00000543873 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| intron-intron | ENST00000574970 | ENST00000556155 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| intron-intron | ENST00000574970 | ENST00000537215 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
| intron-intron | ENST00000574970 | ENST00000454075 | BSG | chr19 | 583492 | + | STAT6 | chr12 | 57496773 | - |
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FusionProtFeatures for BSG_STAT6 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BSG | STAT6 |