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Fusion gene ID: 4431 |
FusionGeneSummary for BRE_PTPN1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BRE_PTPN1 | Fusion gene ID: 4431 | Hgene | Tgene | Gene symbol | BRE | PTPN1 | Gene ID | 5770 |
| Gene name | protein tyrosine phosphatase, non-receptor type 1 | ||
| Synonyms | PTP1B | ||
| Cytomap | 20q13.13 | ||
| Type of gene | protein-coding | ||
| Description | tyrosine-protein phosphatase non-receptor type 1protein tyrosine phosphatase, placentalprotein-tyrosine phosphatase 1B | ||
| Modification date | 20180522 | ||
| UniProtAcc | P18031 | ||
| Ensembl transtripts involved in fusion gene | ENST00000344773, ENST00000379624, ENST00000342045, ENST00000379632, ENST00000361704, ENST00000603461, | ENST00000371621, ENST00000541713, | |
| Fusion gene scores | * DoF score | 7 X 7 X 6=294 | 7 X 5 X 5=175 |
| # samples | 9 | 10 | |
| ** MAII score | log2(9/294*10)=-1.70781924850669 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/175*10)=-0.807354922057604 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: BRE [Title/Abstract] AND PTPN1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |