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Fusion gene ID: 4424 |
FusionGeneSummary for BRD9_TPPP |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BRD9_TPPP | Fusion gene ID: 4424 | Hgene | Tgene | Gene symbol | BRD9 | TPPP | Gene ID | 65980 | 11076 |
| Gene name | bromodomain containing 9 | tubulin polymerization promoting protein | |
| Synonyms | LAVS3040|PRO9856 | TPPP/p25|TPPP1|p24|p25|p25alpha | |
| Cytomap | 5p15.33 | 5p15.33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | bromodomain-containing protein 9rhabdomyosarcoma antigen MU-RMS-40.8sarcoma antigen NY-SAR-29 | tubulin polymerization-promoting protein25 kDa brain-specific proteinbrain specific protein p25 alphaglycogen synthase kinase 3 (GSK3) inhibitor p24p25-alpha | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9H8M2 | O94811 | |
| Ensembl transtripts involved in fusion gene | ENST00000388890, ENST00000323510, ENST00000483173, ENST00000467963, ENST00000435709, ENST00000494422, | ENST00000360578, | |
| Fusion gene scores | * DoF score | 8 X 9 X 6=432 | 4 X 2 X 3=24 |
| # samples | 10 | 4 | |
| ** MAII score | log2(10/432*10)=-2.11103131238874 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/24*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: BRD9 [Title/Abstract] AND TPPP [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | TPPP | GO:0001578 | microtubule bundle formation | 17105200 |
| Tgene | TPPP | GO:0032273 | positive regulation of protein polymerization | 15590652 |
| Tgene | TPPP | GO:0046785 | microtubule polymerization | 18028908 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUAD | TCGA-83-5908-01A | BRD9 | chr5 | 886707 | - | TPPP | chr5 | 666238 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000388890 | ENST00000360578 | BRD9 | chr5 | 886707 | - | TPPP | chr5 | 666238 | - |
| In-frame | ENST00000323510 | ENST00000360578 | BRD9 | chr5 | 886707 | - | TPPP | chr5 | 666238 | - |
| In-frame | ENST00000483173 | ENST00000360578 | BRD9 | chr5 | 886707 | - | TPPP | chr5 | 666238 | - |
| In-frame | ENST00000467963 | ENST00000360578 | BRD9 | chr5 | 886707 | - | TPPP | chr5 | 666238 | - |
| Frame-shift | ENST00000435709 | ENST00000360578 | BRD9 | chr5 | 886707 | - | TPPP | chr5 | 666238 | - |
| 5UTR-3CDS | ENST00000494422 | ENST00000360578 | BRD9 | chr5 | 886707 | - | TPPP | chr5 | 666238 | - |
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FusionProtFeatures for BRD9_TPPP |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BRD9 | TPPP |
| May play a role in the polymerization of tubulin intomicrotubules, microtubule bundling and the stabilization ofexisting microtubules, thus maintaining the integrity of themicrotubule network. May play a role in mitotic spindle assemblyand nuclear envelope breakdown. {ECO:0000269|PubMed:17105200,ECO:0000269|PubMed:17693641, ECO:0000269|PubMed:18028908}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | BRD9 | chr5:886707 | chr5:666238 | ENST00000323510 | - | 4 | 13 | 64_95 | 181 | 502 | Compositional bias | Note=Lys-rich |
| Hgene | BRD9 | chr5:886707 | chr5:666238 | ENST00000388890 | - | 4 | 13 | 64_95 | 161 | 482 | Compositional bias | Note=Lys-rich |
| Hgene | BRD9 | chr5:886707 | chr5:666238 | ENST00000467963 | - | 7 | 16 | 64_95 | 277 | 598 | Compositional bias | Note=Lys-rich |
| Hgene | BRD9 | chr5:886707 | chr5:666238 | ENST00000483173 | - | 7 | 16 | 64_95 | 224 | 545 | Compositional bias | Note=Lys-rich |
| Hgene | BRD9 | chr5:886707 | chr5:666238 | ENST00000467963 | - | 7 | 16 | 153_223 | 277 | 598 | Domain | Bromo |
| Hgene | BRD9 | chr5:886707 | chr5:666238 | ENST00000483173 | - | 7 | 16 | 153_223 | 224 | 545 | Domain | Bromo |
| Hgene | BRD9 | chr5:886707 | chr5:666238 | ENST00000467963 | - | 7 | 16 | 214_216 | 277 | 598 | Region | Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu |
| Hgene | BRD9 | chr5:886707 | chr5:666238 | ENST00000483173 | - | 7 | 16 | 214_216 | 224 | 545 | Region | Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >BRD9 | chr5:886707 | chr5:666238 | ENST00000323510 | - | 4 | 13 | 153_223 | 181 | 502 | Domain | Bromo |
| Hgene | >BRD9 | chr5:886707 | chr5:666238 | ENST00000388890 | - | 4 | 13 | 153_223 | 161 | 482 | Domain | Bromo |
| Hgene | >BRD9 | chr5:886707 | chr5:666238 | ENST00000323510 | - | 4 | 13 | 214_216 | 181 | 502 | Region | Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu |
| Hgene | >BRD9 | chr5:886707 | chr5:666238 | ENST00000388890 | - | 4 | 13 | 214_216 | 161 | 482 | Region | Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu |
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FusionGeneSequence for BRD9_TPPP |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_BRD9_ENST00000388890_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_278aa MKGYQSLVFNFFFLKLSAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFK LMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVIRGKSCRTITFEQFQEALEE LAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGTYD >In-frame_BRD9_ENST00000323510_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_298aa MKGYQSLVFNFFFLKLSAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFK LMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMSFMQDMDFSQQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREV IRGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGR >In-frame_BRD9_ENST00000483173_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_341aa MMTGQTMSERGTKKRKRRRRRSPRRRSIWTMRKEGSERKRRSGSERGSTVTRRERLTTLILGRRWRWSRPQIGQSERAGHSQPKMRAHLF SNSWNTSSASFRDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAG FKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVIRGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGKAP >In-frame_BRD9_ENST00000467963_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_394aa MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKE EKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSK KPSREVIRGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_BRD9_ENST00000388890_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_834nt ATGAAGGGATACCAAAGTCTTGTATTCAATTTTTTTTTCCTTAAATTGTCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAA CACTTCCTCCGCCAGCTTCAGAGAAAAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATA ATAAAACATCCCATGGATTTTGGCACCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAG CTGATGTGTGATAATGCAATGACATACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATG ATGAGCAAACAGGCAGCTCTTTTGGGCAATGAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCC AAGAAATCCAAAAAGCCGAGTAGAGAAGTTATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAG CTCGCCAAGAAGCGATTCAAAGACAAGAGCAGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCA GGGGTGACGAAAGCCATCTCGTCGCCCACAGTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCC TCTGGCAAGGGCAAGGGCAAGGCTGGCCGCGTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGAC >In-frame_BRD9_ENST00000323510_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_894nt ATGAAGGGATACCAAAGTCTTGTATTCAATTTTTTTTTCCTTAAATTGTCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAA CACTTCCTCCGCCAGCTTCAGAGAAAAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATA ATAAAACATCCCATGGATTTTGGCACCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAG CTGATGTGTGATAATGCAATGACATACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATG ATGAGCAAAGAGCGGCTGTTAGCTTTGAAGCGCAGCATGTCGTTTATGCAGGACATGGATTTTTCTCAGCAGGCAGCTCTTTTGGGCAAT GAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAGAAGTT ATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACAAGAGC AGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAAGCCATCTCGTCGCCCACA GTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTGGCCGC >In-frame_BRD9_ENST00000483173_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_1023nt ATGATGACAGGTCAGACCATGAGCGAGAGAGGCACAAAGAAAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACG ATGAGGAAAGAAGGAAGCGAAAGGAAGAGAAGAAGCGGAAGCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATC CTGGGAAGAAGGTGGAGGTGGAGCCGCCCCCAGATCGGCCAGTCCGAGCGTGCCGGACACAGCCAGCCGAAAATGAGAGCACACCTATTC AGCAACTCCTGGAACACTTCCTCCGCCAGCTTCAGAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATAT TCAATGATAATAAAACATCCCATGGATTTTGGCACCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCA GATTTCAAGCTGATGTGTGATAATGCAATGACATACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGC TTTAAGATGATGAGCAAACAGGCAGCTCTTTTGGGCAATGAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTA GAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAGAAGTTATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCG CTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACAAGAGCAGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCC ATCATCTCAGGGGTGACGAAAGCCATCTCGTCGCCCACAGTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGC TTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTGGCCGCGTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGC >In-frame_BRD9_ENST00000467963_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_1182nt ATGGGCAAGAAGCACAAGAAGCACAAGGCCGAGTGGCGCTCGTCCTACGAGGATTATGCCGACAAGCCCCTGGAGAAGCCTCTAAAGCTA GTCCTGAAGGTCGGAGGAAGTGAAGTGACTGAACTCTCAGGATCCGGCCACGACTCCAGTTACTATGATGACAGGTCAGACCATGAGCGA GAGAGGCACAAAGAAAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACGATGAGGAAAGAAGGAAGCGAAAGGAA GAGAAGAAGCGGAAGCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATCCTGGGAAGAAGGTGGAGGTGGAGCCG CCCCCAGATCGGCCAGTCCGAGCGTGCCGGACACAGCCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAACACTTCCTCCGC CAGCTTCAGAGAAAAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATAATAAAACATCCC ATGGATTTTGGCACCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAGCTGATGTGTGAT AATGCAATGACATACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATGATGAGCAAACAG GCAGCTCTTTTGGGCAATGAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAA AAGCCGAGTAGAGAAGTTATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAG CGATTCAAAGACAAGAGCAGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAA GCCATCTCGTCGCCCACAGTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGC AAGGGCAAGGCTGGCCGCGTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGACCAGAAGGTGCAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_BRD9_ENST00000388890_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_5168nt ATGAAGGGATACCAAAGTCTTGTATTCAATTTTTTTTTCCTTAAATTGTCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAA CACTTCCTCCGCCAGCTTCAGAGAAAAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATA ATAAAACATCCCATGGATTTTGGCACCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAG CTGATGTGTGATAATGCAATGACATACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATG ATGAGCAAACAGGCAGCTCTTTTGGGCAATGAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCC AAGAAATCCAAAAAGCCGAGTAGAGAAGTTATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAG CTCGCCAAGAAGCGATTCAAAGACAAGAGCAGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCA GGGGTGACGAAAGCCATCTCGTCGCCCACAGTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCC TCTGGCAAGGGCAAGGGCAAGGCTGGCCGCGTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGAC CAGAAGGTGCAAGGGGGCAAGTAGCCCCCGCTCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTC ATTACATTCCTGTACTAACTGGGGCAGAACTCAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCC TCCTCCTACCGGATGCCCCCAGCACTCCCCTCTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCA GCCATTTCCAAAGTGTCTCGCGGATCACACCACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGC AACAGGAGGCTGTGCTGACCTCCTGAGCGGCAGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAA CACGGAATTGGCCCCACACCGGACGTGGGAGGTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCT TTCCTGGGCAGAGGGCAGAGTGAGGCCACCTGGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTG TGCACACATGCCTACAGGCCAGCTCTGTGCCAAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACC ACAGTGGCTTGGACTGTGAGGGTAGAGTAGGCTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGG AAGATTCAGAATGTCCGGTCCCTGTGGTGTTGCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTC TGCCCGGCCCTCCCGTTCGCCCGTCCTCACTAGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAAC TCTCCCAAAATGGCTCAGCCTAACCTCTCCTGGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTC TGTGGGGGTTTCTCTGCCAGCAGGGGGCTGAGCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGC CTGTCTGCACCTGGGGAGAAGCCGGCGCTCCTGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCC ACTGTCCCTTGGCACGCACACAGCCACAGCCACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAG TCCTGGGGAAACTTTTCCAGAGCCTGTTAGCCCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGT ACAGGAGGGTGGCGAGGCCCCTCCCTCACTGGCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAG CTCCGTGGAAGGACTCCCCCTACCTGAGCAGAGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGG TCTCCGAGGCCCCTCAACAGAGAAGCCTCCACCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGC CTGGAAATAAAGAGCAAGGAAAAATGGACCTCAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCC CAAGCCCAGCCCTGTGCCCCCGCTGAACCTGGCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAA TGTGCGGTTCGGAATCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAG ACGAGCGGTCACCGGAATCGCCCGATCACAGACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCA CAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGA TCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACC CGATCACAGACGAGTGGCCACCGGAATCACCCGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGT CACCAAACAGGGTGGCTCCCCAGGTCCCGAAGCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCC TCCCTGGCCCCAGCGCGGCTCCACCCTGGGCTGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCA CAGTCACGGCCAAGCCACGCAGAACGAACATGACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGG GCGGGTTGGGGTCCGCGGGTCCTCACACCGCACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGA GGAGAGGTGCTGGGCACCAGGACGCTGCCTCCTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGG AGCACACCAGAAACCGGCCCTGAGCACGAGAAGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGA CGGGTCACCTCGCCCACACGGCCAGCACCGACTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTC CCATCTTGGCCCCTGGAGGTGAGCTCATTCACAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGC CACGCCTGTGGGTTTCGTGAATGAGATCGAGGCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGG CCCCACGCCCCCACTCTCCCTCCACACTTCCAGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTC AGACATGCGGGAGCCAGGAGAGCACCCTTCTCCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCT AGCCAGGAGGGGTAGCAAAAATAAAGTCACGAGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCT GTGTGCCGCCTCCGAACACAGAACATTGTTTGGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAAT ATTGTGAATTCAGGCAGGTGTGTGTTCTCTTCTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAA ATGTGTATTTGTGAATAACAAACTGCACAACCTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAG GTTCTGTCGGGGGTGACACCAGGACACAGGGACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACC AGGAGAGAGGGACAGGTTCTGTTGGGGGTGACAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCT GTCAGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGAT CGTGTCTCAGCATCAGGAAAGGAGAAAGGCAGAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTG CTATAGGATAAGCAACCAGGTAGTGTTCCTAACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATA TATATTTATACTGGACTACTTTTACACCTTCTAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTG GCCGCCCCACTTGCCTGTTGGTGCCACTCCATCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCAC >In-frame_BRD9_ENST00000323510_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_5228nt ATGAAGGGATACCAAAGTCTTGTATTCAATTTTTTTTTCCTTAAATTGTCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAA CACTTCCTCCGCCAGCTTCAGAGAAAAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATA ATAAAACATCCCATGGATTTTGGCACCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAG CTGATGTGTGATAATGCAATGACATACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATG ATGAGCAAAGAGCGGCTGTTAGCTTTGAAGCGCAGCATGTCGTTTATGCAGGACATGGATTTTTCTCAGCAGGCAGCTCTTTTGGGCAAT GAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAGAAGTT ATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACAAGAGC AGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAAGCCATCTCGTCGCCCACA GTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTGGCCGC GTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGACCAGAAGGTGCAAGGGGGCAAGTAGCCCCCG CTCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTCATTACATTCCTGTACTAACTGGGGCAGAAC TCAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCCTCCTCCTACCGGATGCCCCCAGCACTCCCC TCTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCAGCCATTTCCAAAGTGTCTCGCGGATCACAC CACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGCAACAGGAGGCTGTGCTGACCTCCTGAGCGG CAGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAACACGGAATTGGCCCCACACCGGACGTGGGA GGTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCTTTCCTGGGCAGAGGGCAGAGTGAGGCCACC TGGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTGTGCACACATGCCTACAGGCCAGCTCTGTGC CAAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACCACAGTGGCTTGGACTGTGAGGGTAGAGTAG GCTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGGAAGATTCAGAATGTCCGGTCCCTGTGGTGT TGCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTCTGCCCGGCCCTCCCGTTCGCCCGTCCTCAC TAGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAACTCTCCCAAAATGGCTCAGCCTAACCTCTCC TGGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTCTGTGGGGGTTTCTCTGCCAGCAGGGGGCTG AGCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGCCTGTCTGCACCTGGGGAGAAGCCGGCGCTC CTGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCCACTGTCCCTTGGCACGCACACAGCCACAGC CACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAGTCCTGGGGAAACTTTTCCAGAGCCTGTTAG CCCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGTACAGGAGGGTGGCGAGGCCCCTCCCTCACT GGCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAGCTCCGTGGAAGGACTCCCCCTACCTGAGCA GAGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGGTCTCCGAGGCCCCTCAACAGAGAAGCCTCC ACCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGCCTGGAAATAAAGAGCAAGGAAAAATGGACC TCAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCCCAAGCCCAGCCCTGTGCCCCCGCTGAACCT GGCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAATGTGCGGTTCGGAATCACCCGATCACAGAC GAGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGATCACA GACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCGATC ACAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCG ATCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGTGGCCACCGGAATCAC CCGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGTCACCAAACAGGGTGGCTCCCCAGGTCCCGA AGCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCCTCCCTGGCCCCAGCGCGGCTCCACCCTGGG CTGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCACAGTCACGGCCAAGCCACGCAGAACGAACA TGACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGGGCGGGTTGGGGTCCGCGGGTCCTCACACCG CACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGAGGAGAGGTGCTGGGCACCAGGACGCTGCCT CCTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGGAGCACACCAGAAACCGGCCCTGAGCACGAG AAGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGACGGGTCACCTCGCCCACACGGCCAGCACCG ACTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTCCCATCTTGGCCCCTGGAGGTGAGCTCATTC ACAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGCCACGCCTGTGGGTTTCGTGAATGAGATCGA GGCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGGCCCCACGCCCCCACTCTCCCTCCACACTTC CAGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTCAGACATGCGGGAGCCAGGAGAGCACCCTTC TCCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCTAGCCAGGAGGGGTAGCAAAAATAAAGTCAC GAGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCTGTGTGCCGCCTCCGAACACAGAACATTGTT TGGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAATATTGTGAATTCAGGCAGGTGTGTGTTCTCT TCTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAAATGTGTATTTGTGAATAACAAACTGCACAA CCTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAGGTTCTGTCGGGGGTGACACCAGGACACAGG GACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGGGGGTG ACAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGAGAGAGGGACAG GTTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGATCGTGTCTCAGCATCAGGAAAGGAGAAAGGC AGAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTGCTATAGGATAAGCAACCAGGTAGTGTTCCT AACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATATATATTTATACTGGACTACTTTTACACCTT CTAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTGGCCGCCCCACTTGCCTGTTGGTGCCACTCC ATCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCACCTCCTACCCCAGCCCCCATCCTGGGCTGCT >In-frame_BRD9_ENST00000483173_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_5497nt TCCGGGCACGCGGACGGGGGTCCTGGGCACCGGGCGAGATTATGCCGACAAGCCCCTGGAGAAGCCTCTAAAGCTAGTCCTGAAGGTCGG AGGAAGTGAAGTGACTGAACTCTCAGGATCCGGCCACGACTCCAGTTACTATGATGACAGGTCAGACCATGAGCGAGAGAGGCACAAAGA AAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACGATGAGGAAAGAAGGAAGCGAAAGGAAGAGAAGAAGCGGAA GCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATCCTGGGAAGAAGGTGGAGGTGGAGCCGCCCCCAGATCGGCC AGTCCGAGCGTGCCGGACACAGCCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAACACTTCCTCCGCCAGCTTCAGAGATC CCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATAATAAAACATCCCATGGATTTTGGCACCATGA AAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAGCTGATGTGTGATAATGCAATGACATACAATA GGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATGATGAGCAAACAGGCAGCTCTTTTGGGCAATG AAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAGAAGTTA TCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACAAGAGCA GCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAAGCCATCTCGTCGCCCACAG TGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTGGCCGCG TGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGACCAGAAGGTGCAAGGGGGCAAGTAGCCCCCGC TCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTCATTACATTCCTGTACTAACTGGGGCAGAACT CAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCCTCCTCCTACCGGATGCCCCCAGCACTCCCCT CTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCAGCCATTTCCAAAGTGTCTCGCGGATCACACC ACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGCAACAGGAGGCTGTGCTGACCTCCTGAGCGGC AGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAACACGGAATTGGCCCCACACCGGACGTGGGAG GTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCTTTCCTGGGCAGAGGGCAGAGTGAGGCCACCT GGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTGTGCACACATGCCTACAGGCCAGCTCTGTGCC AAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACCACAGTGGCTTGGACTGTGAGGGTAGAGTAGG CTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGGAAGATTCAGAATGTCCGGTCCCTGTGGTGTT GCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTCTGCCCGGCCCTCCCGTTCGCCCGTCCTCACT AGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAACTCTCCCAAAATGGCTCAGCCTAACCTCTCCT GGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTCTGTGGGGGTTTCTCTGCCAGCAGGGGGCTGA GCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGCCTGTCTGCACCTGGGGAGAAGCCGGCGCTCC TGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCCACTGTCCCTTGGCACGCACACAGCCACAGCC ACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAGTCCTGGGGAAACTTTTCCAGAGCCTGTTAGC CCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGTACAGGAGGGTGGCGAGGCCCCTCCCTCACTG GCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAGCTCCGTGGAAGGACTCCCCCTACCTGAGCAG AGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGGTCTCCGAGGCCCCTCAACAGAGAAGCCTCCA CCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGCCTGGAAATAAAGAGCAAGGAAAAATGGACCT CAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCCCAAGCCCAGCCCTGTGCCCCCGCTGAACCTG GCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAATGTGCGGTTCGGAATCACCCGATCACAGACG AGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGATCACAG ACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCGATCA CAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCGA TCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGTGGCCACCGGAATCACC CGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGTCACCAAACAGGGTGGCTCCCCAGGTCCCGAA GCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCCTCCCTGGCCCCAGCGCGGCTCCACCCTGGGC TGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCACAGTCACGGCCAAGCCACGCAGAACGAACAT GACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGGGCGGGTTGGGGTCCGCGGGTCCTCACACCGC ACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGAGGAGAGGTGCTGGGCACCAGGACGCTGCCTC CTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGGAGCACACCAGAAACCGGCCCTGAGCACGAGA AGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGACGGGTCACCTCGCCCACACGGCCAGCACCGA CTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTCCCATCTTGGCCCCTGGAGGTGAGCTCATTCA CAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGCCACGCCTGTGGGTTTCGTGAATGAGATCGAG GCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGGCCCCACGCCCCCACTCTCCCTCCACACTTCC AGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTCAGACATGCGGGAGCCAGGAGAGCACCCTTCT CCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCTAGCCAGGAGGGGTAGCAAAAATAAAGTCACG AGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCTGTGTGCCGCCTCCGAACACAGAACATTGTTT GGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAATATTGTGAATTCAGGCAGGTGTGTGTTCTCTT CTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAAATGTGTATTTGTGAATAACAAACTGCACAAC CTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAGGTTCTGTCGGGGGTGACACCAGGACACAGGG ACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGGGGGTGA CAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGAGAGAGGGACAGG TTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGATCGTGTCTCAGCATCAGGAAAGGAGAAAGGCA GAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTGCTATAGGATAAGCAACCAGGTAGTGTTCCTA ACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATATATATTTATACTGGACTACTTTTACACCTTC TAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTGGCCGCCCCACTTGCCTGTTGGTGCCACTCCA TCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCACCTCCTACCCCAGCCCCCATCCTGGGCTGCTG >In-frame_BRD9_ENST00000467963_chr5_886707_-_TPPP_ENST00000360578_chr5_666238_-_5683nt CTGCCGCGGCCCCGCCTCGCCCCGTTTCCGGCGCGGCCCAGCGAGCTCGGCAACCTCGGCGCAGCGAGCGCGGGCGGCCAGCCAGGGCCA GGGGGCGGTGGCGGCCAAGGTCCGACCGGGTGCCAGCTGTTCCCAGCCCCCGCCTCGGGCCCGCCGCCGGCGCCGCCATGGGCAAGAAGC ACAAGAAGCACAAGGCCGAGTGGCGCTCGTCCTACGAGGATTATGCCGACAAGCCCCTGGAGAAGCCTCTAAAGCTAGTCCTGAAGGTCG GAGGAAGTGAAGTGACTGAACTCTCAGGATCCGGCCACGACTCCAGTTACTATGATGACAGGTCAGACCATGAGCGAGAGAGGCACAAAG AAAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACGATGAGGAAAGAAGGAAGCGAAAGGAAGAGAAGAAGCGGA AGCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATCCTGGGAAGAAGGTGGAGGTGGAGCCGCCCCCAGATCGGC CAGTCCGAGCGTGCCGGACACAGCCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAACACTTCCTCCGCCAGCTTCAGAGAA AAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATAATAAAACATCCCATGGATTTTGGCA CCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAGCTGATGTGTGATAATGCAATGACAT ACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATGATGAGCAAACAGGCAGCTCTTTTGG GCAATGAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAG AAGTTATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACA AGAGCAGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAAGCCATCTCGTCGC CCACAGTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTG GCCGCGTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGACCAGAAGGTGCAAGGGGGCAAGTAGC CCCCGCTCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTCATTACATTCCTGTACTAACTGGGGC AGAACTCAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCCTCCTCCTACCGGATGCCCCCAGCAC TCCCCTCTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCAGCCATTTCCAAAGTGTCTCGCGGAT CACACCACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGCAACAGGAGGCTGTGCTGACCTCCTG AGCGGCAGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAACACGGAATTGGCCCCACACCGGACG TGGGAGGTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCTTTCCTGGGCAGAGGGCAGAGTGAGG CCACCTGGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTGTGCACACATGCCTACAGGCCAGCTC TGTGCCAAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACCACAGTGGCTTGGACTGTGAGGGTAG AGTAGGCTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGGAAGATTCAGAATGTCCGGTCCCTGT GGTGTTGCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTCTGCCCGGCCCTCCCGTTCGCCCGTC CTCACTAGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAACTCTCCCAAAATGGCTCAGCCTAACC TCTCCTGGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTCTGTGGGGGTTTCTCTGCCAGCAGGG GGCTGAGCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGCCTGTCTGCACCTGGGGAGAAGCCGG CGCTCCTGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCCACTGTCCCTTGGCACGCACACAGCC ACAGCCACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAGTCCTGGGGAAACTTTTCCAGAGCCT GTTAGCCCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGTACAGGAGGGTGGCGAGGCCCCTCCC TCACTGGCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAGCTCCGTGGAAGGACTCCCCCTACCT GAGCAGAGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGGTCTCCGAGGCCCCTCAACAGAGAAG CCTCCACCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGCCTGGAAATAAAGAGCAAGGAAAAAT GGACCTCAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCCCAAGCCCAGCCCTGTGCCCCCGCTG AACCTGGCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAATGTGCGGTTCGGAATCACCCGATCA CAGACGAGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGA TCACAGACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACC CGATCACAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTC ACCCGATCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGTGGCCACCGGA ATCACCCGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGTCACCAAACAGGGTGGCTCCCCAGGT CCCGAAGCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCCTCCCTGGCCCCAGCGCGGCTCCACC CTGGGCTGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCACAGTCACGGCCAAGCCACGCAGAAC GAACATGACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGGGCGGGTTGGGGTCCGCGGGTCCTCA CACCGCACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGAGGAGAGGTGCTGGGCACCAGGACGC TGCCTCCTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGGAGCACACCAGAAACCGGCCCTGAGC ACGAGAAGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGACGGGTCACCTCGCCCACACGGCCAG CACCGACTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTCCCATCTTGGCCCCTGGAGGTGAGCT CATTCACAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGCCACGCCTGTGGGTTTCGTGAATGAG ATCGAGGCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGGCCCCACGCCCCCACTCTCCCTCCAC ACTTCCAGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTCAGACATGCGGGAGCCAGGAGAGCAC CCTTCTCCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCTAGCCAGGAGGGGTAGCAAAAATAAA GTCACGAGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCTGTGTGCCGCCTCCGAACACAGAACA TTGTTTGGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAATATTGTGAATTCAGGCAGGTGTGTGT TCTCTTCTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAAATGTGTATTTGTGAATAACAAACTG CACAACCTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAC ACAGGGACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGG GGGTGACAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGAGAGAGG GACAGGTTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGATCGTGTCTCAGCATCAGGAAAGGAGA AAGGCAGAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTGCTATAGGATAAGCAACCAGGTAGTG TTCCTAACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATATATATTTATACTGGACTACTTTTAC ACCTTCTAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTGGCCGCCCCACTTGCCTGTTGGTGCC ACTCCATCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCACCTCCTACCCCAGCCCCCATCCTGGG |
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FusionGenePPI for BRD9_TPPP |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| BRD9 | BRD4, WHSC1L1, CATIP, SS18, SMARCD1, MUS81, NFE2L1, CXXC4, BCL7C, BCL7A, SMARCC2, TRIM25, UBE2A | TPPP | HDAC6, SNCA, APP, CDK11B, HIST1H1A, C2orf27B, FADD, GRPEL1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for BRD9_TPPP |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for BRD9_TPPP |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | BRD9 | C0036920 | Sezary Syndrome | 1 | CTD_human |
| Tgene | TPPP | C3826462 | Depression in children | 1 | PSYGENET |
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