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Fusion gene ID: 43854 |
FusionGeneSummary for ZSCAN5A_TESK1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZSCAN5A_TESK1 | Fusion gene ID: 43854 | Hgene | Tgene | Gene symbol | ZSCAN5A | TESK1 | Gene ID | 79149 | 7016 |
| Gene name | zinc finger and SCAN domain containing 5A | testis associated actin remodelling kinase 1 | |
| Synonyms | ZNF495|ZSCAN5 | - | |
| Cytomap | 19q13.43 | 9p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger and SCAN domain-containing protein 5Azinc finger and SCAN domain containing 5zinc finger protein 495 | dual specificity testis-specific protein kinase 1testicular protein kinase 1testis-specific kinase 1 | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q9BUG6 | Q15569 | |
| Ensembl transtripts involved in fusion gene | ENST00000587340, ENST00000254165, ENST00000587492, ENST00000391713, ENST00000592355, ENST00000591078, | ENST00000336395, ENST00000498522, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 1 X 1 X 1=1 |
| # samples | 2 | 1 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ZSCAN5A [Title/Abstract] AND TESK1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BG982433 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000587340 | ENST00000336395 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3UTR | ENST00000587340 | ENST00000498522 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3CDS | ENST00000254165 | ENST00000336395 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3UTR | ENST00000254165 | ENST00000498522 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3CDS | ENST00000587492 | ENST00000336395 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3UTR | ENST00000587492 | ENST00000498522 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3CDS | ENST00000391713 | ENST00000336395 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3UTR | ENST00000391713 | ENST00000498522 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3CDS | ENST00000592355 | ENST00000336395 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3UTR | ENST00000592355 | ENST00000498522 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3CDS | ENST00000591078 | ENST00000336395 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
| intron-3UTR | ENST00000591078 | ENST00000498522 | ZSCAN5A | chr19 | 56802734 | + | TESK1 | chr9 | 35608434 | + |
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FusionProtFeatures for ZSCAN5A_TESK1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZSCAN5A | TESK1 |