	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 43767

FusionGeneSummary for ZNF83_EXOC3L2

Fusion gene summary

Fusion gene information	Fusion gene name: ZNF83_EXOC3L2
	Fusion gene ID: 43767
		Hgene	Tgene
	Gene symbol	ZNF83	EXOC3L2
	Gene ID	55769	90332
	Gene name	zinc finger protein 83	exocyst complex component 3 like 2
	Synonyms	HPF1\|ZNF816B	XTP7
	Cytomap	19q13.41	19q13.32
	Type of gene	protein-coding	protein-coding
	Description	zinc finger protein 83zinc finger protein 816Bzinc finger protein HPF1	exocyst complex component 3-like protein 2HBV X-transactivated gene 7 proteinHBV XAg-transactivated protein 7protein 7 transactivated by hepatitis B virus X antigen (HBxAg)
	Modification date	20180519	20180523
	UniProtAcc	P51522	Q2M3D2
	Ensembl transtripts involved in fusion gene	ENST00000600714, ENST00000601257, ENST00000301096, ENST00000544146, ENST00000536937, ENST00000597597, ENST00000541777, ENST00000545872, ENST00000594682, ENST00000391789, ENST00000596930, ENST00000597161, ENST00000598536, ENST00000600457,	ENST00000252482, ENST00000413988,
Fusion gene scores	* DoF score	6 X 5 X 3=90	4 X 4 X 4=64
	# samples	7	5
	** MAII score	log2(7/90*10)=-0.362570079384708 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ZNF83 [Title/Abstract] AND EXOC3L2 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS3.1			BX283946	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
ChiTaRS3.1			BE735144	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
Frame-shift	ENST00000600714	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000600714	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000601257	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000601257	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
5UTR-3CDS	ENST00000301096	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
5UTR-3CDS	ENST00000301096	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
5UTR-3CDS	ENST00000544146	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
5UTR-3CDS	ENST00000544146	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
5UTR-3CDS	ENST00000536937	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
5UTR-3CDS	ENST00000536937	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
5UTR-3CDS	ENST00000597597	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
5UTR-3CDS	ENST00000597597	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
intron-3CDS	ENST00000541777	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
intron-3CDS	ENST00000541777	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
5UTR-3CDS	ENST00000545872	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
5UTR-3CDS	ENST00000545872	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000594682	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000594682	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
intron-3CDS	ENST00000391789	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
intron-3CDS	ENST00000391789	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000596930	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000596930	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000597161	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000597161	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000598536	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
Frame-shift	ENST00000598536	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
intron-3CDS	ENST00000600457	ENST00000252482	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-
intron-3CDS	ENST00000600457	ENST00000413988	ZNF83	chr19	53138319	-	EXOC3L2	chr19	45728174	-

Top

FusionProtFeatures for ZNF83_EXOC3L2

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ZNF83 P51522	EXOC3L2 Q2M3D2

Home

Download

Statistics

Examples

Help

Contact

Fusion gene ID: 43767

FusionGeneSummary for ZNF83_EXOC3L2

FusionProtFeatures for ZNF83_EXOC3L2